TB-Profiler result

Run: ERR2660539
Summary

Run ID: ERR2660539

Sample name:

Date: 2025-02-11T18:21:35.465512

Number of reads: 1625617

Percentage reads mapped: 62.94

Median coverage: 65.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.99
lineage4.9 Euro-American (H37Rv-like) None 0.94
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ofloxacin
levofloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrB 6738 p.Thr500Asn missense_variant 0.29 levofloxacin Uncertain significance Mutation from literature
moxifloxacin Uncertain significance Mutation from literature
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 645 c.645A>C synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.16 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.17 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 0.17 isoniazid
dnaA 1088 p.Ser363Thr missense_variant 0.19 isoniazid Uncertain significance
dnaA 1092 c.1092T>C synonymous_variant 0.19 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.26 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.28 isoniazid
dnaA 1132 c.1132C>A synonymous_variant 0.29 isoniazid Not assoc w R - Interim
dnaA 1140 c.1140C>G synonymous_variant 0.28 isoniazid
gyrB 5389 c.150C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6115 c.876A>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.19 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6170 p.His311Ala missense_variant 0.25 levofloxacin
moxifloxacin
gyrB 6175 c.936G>A synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrB 6202 c.963C>T synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6203 c.964_966delAGCinsTCG synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGC synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrB 6229 c.990G>A synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.34 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrB 6271 c.1032C>T synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>A upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6310 c.-992G>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrB 6324 c.1085_1086insGTCC frameshift_variant 0.3 levofloxacin Uncertain significance
moxifloxacin
gyrB 6327 c.1090_1093delGAAC frameshift_variant 0.31 levofloxacin Uncertain significance
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.3 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6385 c.-917G>A upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6403 c.-899T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6490 c.-812T>G upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrB 6493 p.Ile418Met missense_variant 0.19 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6502 c.-800T>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 6514 c.1275G>A synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6515 c.-787T>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrB 6542 p.Ile435Leu missense_variant 0.25 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrB 6582 p.Thr448Asn missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.26 levofloxacin
moxifloxacin
gyrB 6597 p.Ser453Cys missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6625 c.-677G>A upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>A upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 6724 c.1485G>T synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6748 c.-554G>A upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 6941 c.-361C>T upstream_gene_variant 0.16 levofloxacin
moxifloxacin
gyrB 6965 p.Ser576Gly missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6970 p.Asp577Glu missense_variant 0.19 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>T upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrB 7047 p.Lys603Met missense_variant 0.21 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.21 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7078 c.-224A>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7096 c.-206G>A upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.3 levofloxacin
moxifloxacin
gyrB 7222 c.1983C>T synonymous_variant 0.24 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7225 c.-77T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 7231 c.-71C>A upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7243 c.-59G>A upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7249 c.-53T>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7252 c.-50G>T upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7299 c.-3T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 7313 c.12G>A synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 7317 c.16T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 7322 c.21G>A synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7325 c.24delTinsCGGA conservative_inframe_insertion&synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 7340 p.Asp13Glu missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 7490 c.189C>A synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7520 c.219G>T synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7556 c.255C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 0.53 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7613 c.312G>A synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7637 c.336C>A synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7673 c.372G>A synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7736 c.435C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7758 p.Ile153Val missense_variant 0.56 levofloxacin Uncertain significance
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7775 c.474C>T synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7818 c.517C>T synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7829 c.528C>T synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>T synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7871 c.570G>A synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7886 c.585T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8309 c.1008G>A synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8382 p.Leu361Met missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.3 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>A synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>A synonymous_variant 0.19 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8740 p.Arg480His missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8761 p.Val487Ala missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 8767 p.Arg489Lys missense_variant 0.36 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8769 p.His490Tyr missense_variant 0.31 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>G synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.43 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8930 c.1629C>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8981 c.1680G>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491181 c.399T>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491206 c.424C>T synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491220 c.438C>T synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491223 c.441C>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491226 c.444C>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491229 c.447C>T synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491238 c.456C>T synonymous_variant 0.19 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491244 c.462T>C synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491248 p.Arg156Thr missense_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.32 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 0.32 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491307 c.525C>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491313 c.531C>T synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491316 c.534C>A synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491319 c.537G>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491340 c.558C>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491343 c.561C>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>A synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491352 c.570C>T synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491367 c.585G>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491370 c.588C>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491379 c.597C>T synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491382 c.600G>A synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491415 c.633A>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491417 p.Arg212Leu missense_variant 0.44 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fgd1 491421 p.Glu213Asp missense_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491427 c.645C>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491430 c.648T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491433 c.651C>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491436 c.654T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491439 p.Asp219Glu missense_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491442 c.660A>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491443 p.Ser221Asp missense_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491447 p.Val222Ala missense_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491454 c.672C>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491472 c.690A>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491493 c.711C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491503 c.721C>T synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491509 c.727T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491523 c.741G>A synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 491571 c.789C>T synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491595 c.813C>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491640 c.858G>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fgd1 491643 c.861G>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
mshA 575714 p.Tyr123Asn missense_variant 0.17 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 0.17 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
nusG 734460 c.207G>C synonymous_variant 0.24 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734544 c.291C>T synonymous_variant 0.28 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.28 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.3 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.22 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.22 rifampicin
nusG 734614 p.Ala121Ser missense_variant 0.18 rifampicin
rpoB 760178 c.372G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>G synonymous_variant 0.19 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 0.21 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.33 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.31 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 0.32 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.34 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.34 rifampicin
rpoB 760354 p.Glu183Ala missense_variant 0.35 rifampicin
rpoB 760357 p.Thr184Asn missense_variant 0.35 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.37 rifampicin Uncertain significance
rpoB 760389 c.583_585delAGCinsTCG synonymous_variant 0.33 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.39 rifampicin Uncertain significance
rpoB 760418 c.612G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760427 c.621G>A synonymous_variant 0.39 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760449 p.Thr215Leu missense_variant 0.37 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760523 c.717C>T synonymous_variant 0.4 rifampicin
rpoB 760527 p.Gln241Ala missense_variant 0.4 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Arg missense_variant 0.4 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.41 rifampicin Uncertain significance
rpoB 760587 p.Thr261Ala missense_variant 0.42 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.4 rifampicin
rpoB 760593 p.Gly263Asn missense_variant 0.4 rifampicin
rpoB 760596 p.Thr264Ser missense_variant 0.4 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.34 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.29 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>G synonymous_variant 0.19 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.27 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760979 c.1173G>A synonymous_variant 0.31 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.3 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.36 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.41 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.41 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.41 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.42 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 0.42 rifampicin
rpoB 761198 c.1392G>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.43 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 0.41 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 0.4 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761289 p.Ser495Ala missense_variant 0.33 rifampicin
rpoB 761292 p.Val496Thr missense_variant 0.31 rifampicin
rpoB 761330 c.1524G>C synonymous_variant 0.25 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.22 rifampicin
rpoB 761346 p.Val514Asn missense_variant 0.21 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.22 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761366 c.1560C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761375 c.1569G>C synonymous_variant 0.22 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761834 c.2028T>C synonymous_variant 0.22 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 0.23 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 0.23 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.23 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761868 p.Asp688Gln missense_variant 0.24 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 0.25 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.25 rifampicin
rpoB 761897 c.2091C>G synonymous_variant 0.26 rifampicin
rpoB 761903 c.2097T>C synonymous_variant 0.25 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.24 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.23 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.23 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.23 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.26 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762006 c.2200_2202delCGCinsAGG synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762024 p.Val740Thr missense_variant 0.4 rifampicin Uncertain significance
rpoB 762029 c.2223C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.51 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.52 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.53 rifampicin
rpoB 762134 c.2328C>A synonymous_variant 0.52 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.52 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.52 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 0.47 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>A synonymous_variant 0.46 rifampicin
rpoB 762212 c.2406G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762227 c.2421G>A synonymous_variant 0.43 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762281 c.2475G>A synonymous_variant 0.5 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.51 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.53 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.51 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.51 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.51 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 0.51 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.43 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.43 rifampicin
rpoC 762407 c.-963G>C upstream_gene_variant 0.41 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762490 p.Val895Ala missense_variant 0.26 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.23 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.23 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 0.21 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.2 rifampicin
rpoB 762768 p.Pro988Ala missense_variant 0.19 rifampicin Uncertain significance
rpoB 762782 c.2976T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762788 c.2982G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.17 rifampicin Uncertain significance
rpoB 762795 p.Asp997Asn missense_variant 0.18 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 0.17 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762818 c.3012C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 762827 c.-543G>T upstream_gene_variant 0.27 rifampicin
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762894 c.3088C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762926 c.3120C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.28 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.28 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.28 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.31 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 0.27 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.21 rifampicin
rpoB 763203 p.Ser1133Ala missense_variant 0.21 rifampicin Uncertain significance
rpoB 763207 p.Ser1134Lys missense_variant 0.21 rifampicin Uncertain significance
rpoB 763227 c.3421C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763430 c.61A>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 763447 c.78C>T synonymous_variant 0.37 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 0.4 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 0.32 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.32 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.34 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.3 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.28 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.28 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763774 c.405G>C synonymous_variant 0.25 rifampicin
rpoC 763780 c.411C>T synonymous_variant 0.19 rifampicin
rpoC 763781 p.Ser138Thr missense_variant 0.16 rifampicin
rpoC 763822 c.453C>G synonymous_variant 0.17 rifampicin
rpoC 763825 c.456G>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 0.17 rifampicin
rpoC 763844 p.Arg159Asn missense_variant 0.17 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.19 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.22 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.24 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.24 rifampicin
rpoC 763888 c.519G>T synonymous_variant 0.24 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.24 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.26 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 0.27 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.25 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.25 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763991 p.Ile208Leu missense_variant 0.31 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.31 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.31 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.32 rifampicin
rpoC 764020 c.651C>T synonymous_variant 0.32 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.32 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.33 rifampicin
rpoC 764030 p.Asp221Asn missense_variant 0.33 rifampicin Uncertain significance
rpoC 764039 p.Ser224Asp missense_variant 0.33 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.32 rifampicin
rpoC 764048 p.Thr227Val missense_variant 0.33 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.33 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.32 rifampicin
rpoC 764085 p.Asn239Thr missense_variant 0.32 rifampicin Uncertain significance
rpoC 764087 p.Leu240Val missense_variant 0.32 rifampicin Uncertain significance
rpoC 764095 c.726C>G synonymous_variant 0.36 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764116 c.747C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764134 c.765C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 0.41 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 0.42 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.43 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Thr missense_variant 0.43 rifampicin Uncertain significance
rpoC 764213 p.Arg282Lys missense_variant 0.43 rifampicin Uncertain significance
rpoC 764236 c.867G>A synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.44 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.45 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.45 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.46 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.49 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.53 rifampicin
rpoC 764341 c.972G>T synonymous_variant 0.5 rifampicin
rpoC 764347 c.978G>C synonymous_variant 0.49 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.46 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 0.48 rifampicin
rpoC 764429 c.1060C>T synonymous_variant 0.46 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.45 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.45 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.46 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.46 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.47 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 0.42 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 0.41 rifampicin
rpoC 764635 c.1266C>G synonymous_variant 0.41 rifampicin
rpoC 764638 c.1269C>T synonymous_variant 0.38 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.36 rifampicin
rpoC 764650 c.1281G>C synonymous_variant 0.36 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 0.36 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.35 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764665 c.1296C>G synonymous_variant 0.37 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>A synonymous_variant 0.34 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>G synonymous_variant 0.35 rifampicin
rpoC 764809 c.1440C>G synonymous_variant 0.35 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.37 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.34 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.34 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764941 c.1572G>C synonymous_variant 0.4 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.38 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.38 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.34 rifampicin
rpoC 765076 c.1707A>T synonymous_variant 0.35 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.35 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>T synonymous_variant 0.33 rifampicin
rpoC 765157 c.1788C>A synonymous_variant 0.16 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 0.21 rifampicin
rpoC 765234 p.Ala622Val missense_variant 0.23 rifampicin
rpoC 765246 p.Val626Ala missense_variant 0.24 rifampicin
rpoC 765277 c.1908G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765280 c.1911G>C synonymous_variant 0.24 rifampicin
rpoC 765281 p.Thr638Asp missense_variant 0.25 rifampicin Uncertain significance
rpoC 765292 c.1923G>T synonymous_variant 0.25 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.24 rifampicin Uncertain significance
rpoC 765303 p.Glu645Ala missense_variant 0.24 rifampicin
rpoC 765305 p.Ile646Val missense_variant 0.24 rifampicin Uncertain significance
rpoC 765311 p.Ala648Thr missense_variant 0.26 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Glu missense_variant 0.26 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.26 rifampicin Uncertain significance
rpoC 765339 p.Gln657Arg missense_variant 0.26 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765404 p.Leu679Thr missense_variant 0.27 rifampicin Uncertain significance
rpoC 765409 c.2040T>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765421 c.2052C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765453 p.Ala695Val missense_variant 0.4 rifampicin Uncertain significance
rpoC 765478 c.2109T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765547 c.2178C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.37 rifampicin
rpoC 765553 c.2184C>G synonymous_variant 0.38 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 0.39 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.39 rifampicin
rpoC 765611 p.His748Ser missense_variant 0.45 rifampicin Uncertain significance
rpoC 765625 c.2256C>T synonymous_variant 0.46 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765662 c.2293_2295delTTGinsCTC synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765718 p.Asp783Glu missense_variant 0.5 rifampicin Uncertain significance
rpoC 765724 c.2355C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.52 rifampicin
rpoC 765742 p.Glu791Asp missense_variant 0.54 rifampicin Uncertain significance
rpoC 765751 c.2382C>G synonymous_variant 0.54 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.54 rifampicin Uncertain significance
rpoC 765787 c.2418C>T synonymous_variant 0.57 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.55 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.55 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.53 rifampicin Uncertain significance
rpoC 765904 c.2535C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>G synonymous_variant 0.45 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766303 c.2934C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766309 c.2940G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.19 rifampicin
rpoC 766345 c.2976T>G synonymous_variant 0.28 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.28 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.3 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.34 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.35 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766423 c.3054T>C synonymous_variant 0.38 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.38 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.38 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 0.38 rifampicin
rpoC 766468 c.3099G>A synonymous_variant 0.4 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 0.34 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.34 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.37 rifampicin
rpoC 766517 p.Thr1050Ala missense_variant 0.34 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.33 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.33 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.32 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.32 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.32 rifampicin
rpoC 766547 p.Arg1060Lys missense_variant 0.33 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 0.35 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.35 rifampicin
rpoC 766576 c.3207C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.38 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.4 rifampicin
rpoC 766610 p.Ser1081Pro missense_variant 0.4 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.42 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.41 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.39 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.39 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 0.39 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.36 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 0.38 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 0.38 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.41 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 0.38 rifampicin
rpoC 766696 c.3327G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766702 c.3333G>C synonymous_variant 0.41 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.4 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.4 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.41 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.31 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.33 rifampicin
rpoC 766787 p.Glu1140Gln missense_variant 0.34 rifampicin Uncertain significance
rpoC 766798 c.3429C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.38 rifampicin Uncertain significance
rpoC 766888 c.3519G>C synonymous_variant 0.37 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.38 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.38 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.38 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.36 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.35 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.35 rifampicin
rpoC 766918 c.3549C>G synonymous_variant 0.34 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 0.35 rifampicin
rpoC 766931 p.Ala1188Thr missense_variant 0.34 rifampicin Uncertain significance
rpoC 766945 c.3576A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 767030 c.3661C>T synonymous_variant 0.36 rifampicin
rpoC 767059 c.3690T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.35 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767191 c.3822C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>T synonymous_variant 0.27 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
mmpL5 775915 p.Ala856Ser missense_variant 0.19 bedaquiline
clofazimine
mmpL5 775916 c.2565T>G synonymous_variant 0.2 bedaquiline
clofazimine
mmpL5 775937 c.2544G>C synonymous_variant 0.18 bedaquiline
clofazimine
mmpL5 775961 c.2520C>G synonymous_variant 0.18 bedaquiline
clofazimine
rpsL 781628 c.69T>C synonymous_variant 0.19 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.19 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.31 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.31 streptomycin
rpsL 781664 c.105C>T synonymous_variant 0.36 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.46 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.48 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>G synonymous_variant 0.48 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.44 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.45 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.46 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.45 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.44 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.44 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.43 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.43 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.45 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.46 streptomycin Not assoc w R - Interim
rpsL 781799 c.240G>A synonymous_variant 0.46 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.45 streptomycin
rpsL 781829 c.270G>T synonymous_variant 0.42 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.42 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.38 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.38 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.36 streptomycin
rpsL 781877 c.318T>G synonymous_variant 0.37 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.35 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.35 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.33 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.31 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.33 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.18 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.24 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.25 linezolid
rplC 800558 c.-251G>A upstream_gene_variant 0.27 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.29 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.28 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.28 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.29 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.29 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.28 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.28 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.27 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.27 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.25 linezolid
fbiC 1303611 c.681G>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
sigE 1364826 c.414C>G synonymous_variant 0.17 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.17 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 0.17 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.17 pyrazinamide
sigE 1364872 p.Ile154Val missense_variant 0.18 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.18 pyrazinamide
sigE 1364895 c.483G>A synonymous_variant 0.2 pyrazinamide
sigE 1364901 c.489C>T synonymous_variant 0.22 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.26 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.25 pyrazinamide
sigE 1364926 p.Asn172Asp missense_variant 0.24 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.27 pyrazinamide
sigE 1364960 p.Gly183Asp missense_variant 0.24 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>G synonymous_variant 0.26 pyrazinamide
sigE 1364979 c.567C>G synonymous_variant 0.24 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.25 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
sigE 1364992 p.Pro194Ala missense_variant 0.25 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.25 pyrazinamide
sigE 1365006 c.594T>G synonymous_variant 0.25 pyrazinamide
sigE 1365009 c.597C>G synonymous_variant 0.25 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.24 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.25 pyrazinamide
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.28 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.3 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>C non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472292 n.447A>G non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453delGinsCT non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472300 n.455C>G non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468G>C non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470delTinsGG non_coding_transcript_exon_variant 0.73 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.76 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.76 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838_839insTA non_coding_transcript_exon_variant 0.77 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.74 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473084 n.1239T>C non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>T non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.55 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1473812 n.155G>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473828 n.171_175delGGTGCinsCCGGTG non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1473982 n.325_326delGAinsTGT non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1473985 n.328A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473989 n.333delT non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1473992 n.335A>G non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1473994 n.337C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.26 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474005 n.348T>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474007 n.350A>G non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474008 n.351G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474016 n.359C>G non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474026 n.369C>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474105 n.448_449delTAinsCGATG non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474107 n.451_453delCAA non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1474287 n.630_644delTCCTTTTCCTCTCCGinsCTCCCTT non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474415 n.760_765delACACGC non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474426 n.769T>C non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474428 n.771C>A non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474430 n.773C>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474708 n.1052dupG non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474711 n.1054_1055insA non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474715 n.1061delA non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474952 n.1296delC non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474956 n.1299C>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474957 n.1301_1308delACCTTGTG non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474968 n.1311G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474969 n.1312G>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474972 n.1315delGinsAT non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474995 n.1338T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474997 n.1340A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475008 n.1351C>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475015 n.1358_1360delCCGinsTCTA non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1475374 n.1717_1718insAC non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475379 n.1722G>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475380 n.1724_1725delGA non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475395 n.1738T>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475402 n.1745delCinsTA non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475405 n.1748A>G non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1475408 n.1752delT non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1475428 n.1771G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475433 n.1776A>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475482 n.1825A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1476108 n.2451T>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476746 n.3089T>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
inhA 1673778 c.-424C>G upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673805 c.-397G>C upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1673808 c.-394A>C upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1673811 c.-391G>A upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673829 c.-373C>G upstream_gene_variant 0.2 isoniazid
ethionamide
inhA 1673830 c.-372_-370delAAAinsCGG upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673841 c.-361A>G upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673844 c.-358G>C upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673853 c.-349A>C upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673856 c.-346T>G upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673865 c.-337C>G upstream_gene_variant 0.2 isoniazid
ethionamide
inhA 1673870 c.-332_-331delGCinsTG upstream_gene_variant 0.2 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 0.23 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.23 isoniazid
ethionamide
inhA 1673916 c.-286A>T upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1673941 c.-261_-259delGCCinsTCG upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673982 c.-220G>C upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673985 c.-217C>A upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673988 c.-214G>C upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 0.23 isoniazid
ethionamide
inhA 1674699 c.498C>T synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674830 p.Glu210Gly missense_variant 0.21 isoniazid
ethionamide
inhA 1674837 c.636C>T synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674839 p.Ala213Glu missense_variant 0.21 isoniazid
ethionamide
inhA 1674848 p.Gln216Arg missense_variant 0.19 isoniazid Uncertain significance
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.22 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674883 p.Ile228Val missense_variant 0.19 isoniazid Uncertain significance
ethionamide Uncertain significance
rpsA 1833578 p.Val13Ile missense_variant 0.19 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 0.19 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.2 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.23 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.27 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.3 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.3 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.3 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.34 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.34 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.35 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.37 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.37 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.37 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.36 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.38 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 0.35 pyrazinamide
rpsA 1833770 p.Asn77His missense_variant 0.35 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 0.39 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.39 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.39 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833814 c.273C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.42 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.44 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.44 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.44 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.43 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.43 pyrazinamide
rpsA 1833919 c.378C>T synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
rpsA 1833928 c.387G>C synonymous_variant 0.4 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.38 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.39 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834040 p.Lys167Arg missense_variant 0.41 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.38 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.3 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.3 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.3 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.3 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.3 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834172 p.Ile211Val missense_variant 0.3 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.38 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834297 c.756C>G synonymous_variant 0.42 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.42 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.48 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
rpsA 1834411 c.870T>C synonymous_variant 0.46 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834432 c.891G>T synonymous_variant 0.47 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.49 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.45 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.46 pyrazinamide
rpsA 1834527 p.Arg329Gln missense_variant 0.45 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.42 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834558 c.1017C>G synonymous_variant 0.43 pyrazinamide
rpsA 1834603 p.Glu354Asp missense_variant 0.47 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 0.46 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.44 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.46 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.51 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.51 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.39 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.38 pyrazinamide
rpsA 1834751 p.Leu404Ile missense_variant 0.34 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.34 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 0.36 pyrazinamide
rpsA 1834762 c.1221C>T synonymous_variant 0.36 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.36 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.38 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.38 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.38 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.39 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.34 linezolid
tsnR 1853370 c.-236_-234delGCAinsACC upstream_gene_variant 0.36 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.32 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.32 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.31 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.25 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.25 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.23 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.23 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.2 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.18 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.19 linezolid
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
kasA 2518504 c.390T>C synonymous_variant 0.2 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.22 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.29 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.33 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.38 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.39 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.38 isoniazid
kasA 2518585 c.471G>A synonymous_variant 0.35 isoniazid
kasA 2518588 c.474T>G synonymous_variant 0.34 isoniazid
kasA 2518591 c.477G>T synonymous_variant 0.36 isoniazid
kasA 2518594 c.480C>T synonymous_variant 0.36 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.36 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.37 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.45 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.46 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.49 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.47 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.45 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.45 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.43 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.42 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.42 isoniazid
kasA 2518726 c.612G>A synonymous_variant 0.39 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.38 isoniazid
kasA 2518741 c.627G>A synonymous_variant 0.39 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.36 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.27 isoniazid
kasA 2518759 c.645C>G synonymous_variant 0.27 isoniazid
kasA 2518765 c.651G>C synonymous_variant 0.25 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.26 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.27 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.26 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.25 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.25 isoniazid
kasA 2518811 p.Asp233Asn missense_variant 0.24 isoniazid
kasA 2518816 c.702C>G synonymous_variant 0.24 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.19 isoniazid
Rv2477c 2782777 c.1266A>T synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782816 c.1227T>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782828 c.1215T>G synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782840 c.1203C>G synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782858 c.1185C>T synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782869 p.Ala392Ser missense_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782876 c.1167G>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782894 c.1149C>G synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782900 c.1143C>T synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783373 p.Glu224Gln missense_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>G synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783433 p.Ser204Gly missense_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783439 c.604C>T synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783444 p.Gln200Ala missense_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.21 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783517 p.Ser176Ala missense_variant 0.23 kanamycin Uncertain significance
levofloxacin
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783520 c.523T>C synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783523 c.520C>T synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783617 c.426G>A synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783626 p.Ala139Ser missense_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783646 p.Asp133Asn missense_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783767 c.276C>T synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783837 p.Thr69Ser missense_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783842 c.201C>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783847 p.Thr66Pro missense_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>A synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783875 p.Lys56Thr missense_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>G synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.28 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783926 c.117C>G synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783950 c.93C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Leu missense_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783986 c.57G>C synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3066018 c.174T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066045 c.147T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067406 c.540A>G synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067680 p.Cys89Ser missense_variant 0.18 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067694 c.252G>A synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067706 c.240C>T synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067710 p.Ser79Arg missense_variant 0.19 para-aminosalicylic_acid
thyX 3067716 p.Ser77Val missense_variant 0.19 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067748 c.198C>T synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067763 c.183C>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 0.26 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067847 c.99C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.2 para-aminosalicylic_acid
thyX 3067874 p.Pro24Ala missense_variant 0.2 para-aminosalicylic_acid
mtrB 3625623 p.Thr331Ser missense_variant 0.16 rifampicin
bedaquiline
lpqB 3625630 c.-720C>G upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3625637 p.Ala326Asp missense_variant 0.24 rifampicin
bedaquiline
mtrB 3625648 p.Tyr322His missense_variant 0.22 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625657 c.-747C>T upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625663 c.-753G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625696 c.-786A>G upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625720 c.-810G>A upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625732 c.882C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.43 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625804 c.-896_-894delAGGinsCGC upstream_gene_variant 0.42 rifampicin
bedaquiline
lpqB 3625816 c.-906C>T upstream_gene_variant 0.41 rifampicin
bedaquiline
lpqB 3625822 c.-912C>T upstream_gene_variant 0.37 rifampicin
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625848 c.766C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625849 c.-939T>C upstream_gene_variant 0.35 rifampicin
bedaquiline
lpqB 3625852 c.-942A>C upstream_gene_variant 0.35 rifampicin
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 0.36 rifampicin
bedaquiline
lpqB 3625882 c.-972G>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3625899 p.Val239Leu missense_variant 0.29 rifampicin
bedaquiline
lpqB 3625909 c.-999T>G upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3625924 c.690G>A synonymous_variant 0.24 rifampicin
bedaquiline
mtrB 3625927 c.687T>C synonymous_variant 0.23 rifampicin
bedaquiline
mtrB 3625936 c.678C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626750 c.-137T>C upstream_gene_variant 0.18 rifampicin
bedaquiline
mtrB 3626756 c.-143C>T upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3626776 c.-163A>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626789 c.561C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3626804 c.-191A>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrA 3626822 p.Asp176Glu missense_variant 0.33 rifampicin
bedaquiline
mtrB 3626843 c.-230G>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626849 c.-236C>T upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626858 c.-245A>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626864 c.-253_-251delTTGinsCTA upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626881 c.-268C>T upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3626891 c.-278G>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrA 3626907 p.Asn148Ala missense_variant 0.3 rifampicin
bedaquiline
mtrA 3626912 p.Thr146Ser missense_variant 0.29 rifampicin
bedaquiline
mtrB 3626915 c.-302C>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrA 3626939 p.Glu137Asp missense_variant 0.34 rifampicin
bedaquiline
mtrA 3626942 p.Val136Ile missense_variant 0.35 rifampicin
bedaquiline
mtrB 3626954 c.-341C>G upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrA 3626969 c.381C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626996 c.-383G>C upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrA 3627026 c.324G>A synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrA 3627056 c.294C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627068 c.-455T>A upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrA 3627131 p.Ala73Lys missense_variant 0.27 rifampicin
bedaquiline
mtrB 3627139 c.-526T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627140 c.-527G>A upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTG upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3627191 c.-578G>C upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrA 3627212 p.Arg46His missense_variant 0.31 rifampicin
bedaquiline
mtrB 3627224 c.-611G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627227 c.-614T>A upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627247 p.Ile35Val missense_variant 0.27 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3627301 c.-688T>C upstream_gene_variant 0.22 rifampicin
bedaquiline
rpoA 3877545 c.963G>C synonymous_variant 0.19 rifampicin
rpoA 3877548 c.960C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877553 p.Glu319Gln missense_variant 0.2 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877569 p.Pro313Ala missense_variant 0.26 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877623 c.885C>T synonymous_variant 0.29 rifampicin
rpoA 3877629 c.879C>G synonymous_variant 0.32 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.35 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.38 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877803 c.705G>C synonymous_variant 0.44 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.37 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.38 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 0.34 rifampicin
rpoA 3877893 c.615C>G synonymous_variant 0.33 rifampicin
rpoA 3877905 c.603A>C synonymous_variant 0.34 rifampicin
rpoA 3877908 c.600T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3877929 p.Ile193Val missense_variant 0.33 rifampicin Uncertain significance
rpoA 3877959 c.549C>G synonymous_variant 0.34 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.3 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 0.3 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3878091 p.Val139Ile missense_variant 0.17 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.17 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.19 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.2 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.22 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.21 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.25 rifampicin Uncertain significance
rpoA 3878145 c.363C>T synonymous_variant 0.25 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.31 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.34 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.45 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 0.49 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.5 rifampicin
rpoA 3878276 c.232C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.52 rifampicin Uncertain significance
rpoA 3878295 c.213A>G synonymous_variant 0.51 rifampicin
rpoA 3878304 c.204G>C synonymous_variant 0.53 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.52 rifampicin
rpoA 3878322 c.186A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.48 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.48 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.47 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3878394 c.114G>T synonymous_variant 0.44 rifampicin
rpoA 3878400 c.108T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 0.42 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.4 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.37 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.31 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.3 rifampicin
rpoA 3878465 p.Thr15Ala missense_variant 0.19 rifampicin
rpoA 3878725 c.-218A>T upstream_gene_variant 0.32 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.31 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.38 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.39 rifampicin Uncertain significance
rpoA 3878758 c.-251G>C upstream_gene_variant 0.38 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.38 rifampicin
rpoA 3878775 c.-268A>G upstream_gene_variant 0.4 rifampicin Uncertain significance
rpoA 3878779 c.-272C>T upstream_gene_variant 0.4 rifampicin Uncertain significance
rpoA 3878785 c.-278T>C upstream_gene_variant 0.41 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.41 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.42 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.4 rifampicin
rpoA 3878830 c.-325_-323delCTGinsATC upstream_gene_variant 0.34 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.34 rifampicin
rpoA 3878843 c.-337_-336delCGinsAA upstream_gene_variant 0.33 rifampicin
rpoA 3878845 c.-338G>C upstream_gene_variant 0.32 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.34 rifampicin
rpoA 3878873 c.-366G>A upstream_gene_variant 0.29 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.28 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 0.27 rifampicin
rpoA 3878887 c.-382_-380delAACinsGAT upstream_gene_variant 0.29 rifampicin
rpoA 3878893 c.-388_-386delCACinsAAG upstream_gene_variant 0.26 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.29 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.29 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.31 rifampicin
rpoA 3878947 c.-440G>T upstream_gene_variant 0.32 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 0.31 rifampicin
rpoA 3878962 c.-455G>C upstream_gene_variant 0.3 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoA 3878977 c.-470C>G upstream_gene_variant 0.22 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoA 3879073 c.-566A>G upstream_gene_variant 0.22 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.23 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.28 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.29 rifampicin
rpoA 3879097 c.-590C>G upstream_gene_variant 0.31 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.32 rifampicin
rpoA 3879125 c.-618T>G upstream_gene_variant 0.28 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.29 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.3 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.29 rifampicin
rpoA 3879166 c.-659C>T upstream_gene_variant 0.28 rifampicin
rpoA 3879190 c.-683C>A upstream_gene_variant 0.27 rifampicin
rpoA 3879199 c.-692C>T upstream_gene_variant 0.26 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.25 rifampicin
ddn 3986618 c.-226C>T upstream_gene_variant 0.27 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.22 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.21 pretomanid
delamanid
ddn 3986690 c.-154C>A upstream_gene_variant 0.17 pretomanid
delamanid
clpC1 4038519 p.Arg729Gln missense_variant 0.16 pyrazinamide
clpC1 4038530 c.2175G>A synonymous_variant 0.16 pyrazinamide
clpC1 4038535 p.Arg724Ser missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038563 c.2142C>T synonymous_variant 0.23 pyrazinamide
clpC1 4038587 c.2118C>T synonymous_variant 0.25 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.27 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.27 pyrazinamide
clpC1 4038605 c.2100G>A synonymous_variant 0.29 pyrazinamide
clpC1 4038611 c.2094C>T synonymous_variant 0.27 pyrazinamide
clpC1 4038620 p.Gln695Leu missense_variant 0.27 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.28 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.28 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.27 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.27 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.25 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.26 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.29 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4038698 c.2007C>T synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 0.37 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.38 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.38 pyrazinamide
clpC1 4038726 p.Thr660Cys missense_variant 0.42 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.4 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.44 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.42 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.4 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.4 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4038794 c.1909_1911delAGCinsTCG synonymous_variant 0.41 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.39 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 0.38 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>T synonymous_variant 0.4 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.33 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.32 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.31 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.32 pyrazinamide
clpC1 4038923 c.1782A>C synonymous_variant 0.34 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.29 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.28 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.24 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.26 pyrazinamide
clpC1 4038995 c.1708_1710delTTGinsCTC synonymous_variant 0.25 pyrazinamide
clpC1 4039001 p.Asn568Glu missense_variant 0.25 pyrazinamide
clpC1 4039004 c.1701C>G synonymous_variant 0.25 pyrazinamide
clpC1 4039010 c.1695G>A synonymous_variant 0.28 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.29 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.31 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.3 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 0.3 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039127 p.Lys526Ala missense_variant 0.31 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039141 p.Glu522Lys missense_variant 0.31 pyrazinamide
clpC1 4039166 c.1539G>A synonymous_variant 0.3 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.29 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.3 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 0.31 pyrazinamide
clpC1 4039243 c.1462C>T synonymous_variant 0.34 pyrazinamide
clpC1 4039250 c.1455C>T synonymous_variant 0.3 pyrazinamide
clpC1 4039271 c.1434G>A synonymous_variant 0.3 pyrazinamide
clpC1 4039274 c.1431G>A synonymous_variant 0.29 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 0.29 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.27 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.26 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.26 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.26 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4039328 c.1377A>G synonymous_variant 0.26 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.28 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.26 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.25 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.23 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.24 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.24 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.25 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.31 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.34 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.34 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039501 c.1204C>T synonymous_variant 0.34 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039559 c.1146C>A synonymous_variant 0.34 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.35 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 0.36 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Ser missense_variant 0.37 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4039581 p.Thr375Ser missense_variant 0.36 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.31 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039652 c.1053G>A synonymous_variant 0.29 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.28 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039688 c.1017G>A synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4039694 c.1011G>T synonymous_variant 0.3 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.35 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039736 c.969C>T synonymous_variant 0.34 pyrazinamide
clpC1 4039739 c.966C>T synonymous_variant 0.35 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.36 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.36 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.37 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.37 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.33 pyrazinamide
clpC1 4039856 c.849C>T synonymous_variant 0.34 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.33 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.33 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.32 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 0.34 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.29 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.29 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.34 pyrazinamide
clpC1 4040001 p.His235Ala missense_variant 0.33 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.36 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 0.36 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.36 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 0.36 pyrazinamide
clpC1 4040054 c.651G>A synonymous_variant 0.39 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.4 pyrazinamide
clpC1 4040081 c.624C>T synonymous_variant 0.38 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.34 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040108 c.597G>A synonymous_variant 0.37 pyrazinamide
clpC1 4040126 c.579C>G synonymous_variant 0.38 pyrazinamide
clpC1 4040135 c.570C>G synonymous_variant 0.39 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.37 pyrazinamide
clpC1 4040165 c.540G>C synonymous_variant 0.35 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.34 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.34 pyrazinamide
clpC1 4040177 c.528C>T synonymous_variant 0.36 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.38 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.37 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.37 pyrazinamide
clpC1 4040213 c.492T>G synonymous_variant 0.38 pyrazinamide
clpC1 4040216 c.489C>T synonymous_variant 0.38 pyrazinamide
clpC1 4040225 c.480A>G synonymous_variant 0.38 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.34 pyrazinamide
clpC1 4040231 c.474C>G synonymous_variant 0.35 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.3 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.29 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.28 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.3 pyrazinamide
clpC1 4040315 p.Glu130Asp missense_variant 0.31 pyrazinamide
clpC1 4040336 c.369G>A synonymous_variant 0.29 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.27 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.26 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.26 pyrazinamide
clpC1 4040363 c.342A>G synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040369 c.336C>G synonymous_variant 0.26 pyrazinamide
clpC1 4040372 c.333C>T synonymous_variant 0.26 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.25 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.26 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.26 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.28 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4040432 c.273C>T synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
clpC1 4040444 c.261C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040465 c.240T>C synonymous_variant 0.34 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.35 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040513 c.192G>A synonymous_variant 0.41 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.4 pyrazinamide
clpC1 4040540 c.165G>C synonymous_variant 0.4 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.38 pyrazinamide
clpC1 4040573 c.132T>G synonymous_variant 0.38 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.36 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.36 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.33 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTC synonymous_variant 0.32 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.32 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.34 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.31 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.25 pyrazinamide
clpC1 4040645 c.60C>G synonymous_variant 0.25 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040660 c.45G>C synonymous_variant 0.24 pyrazinamide
clpC1 4040669 c.36C>T synonymous_variant 0.23 pyrazinamide
clpC1 4040681 c.24T>G synonymous_variant 0.21 pyrazinamide
glpK 4138464 p.Gly431Ala missense_variant 0.22 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138472 c.1284G>T synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138478 c.1278T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138481 c.1275G>A synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138490 c.1266G>T synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138494 p.Gln421Gly missense_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138500 p.Arg419His missense_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138502 c.1254T>G synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138511 c.1245C>T synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138523 c.1233C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138526 p.Asp410Glu missense_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138529 p.Val409Ala missense_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138532 c.1224G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138538 c.1218C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138547 c.1209C>T synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138550 c.1206C>T synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138568 c.1188A>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138571 c.1185C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138574 c.1182G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138598 c.1158G>A synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138601 c.1155G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138622 c.1134C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138631 c.1125C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>T synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138643 c.1113A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138655 c.1101G>A synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138661 c.1095T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138664 c.1092G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138667 c.1089G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138676 c.1080T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138685 c.1071C>G synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embA 4244930 c.1698G>C synonymous_variant 0.22 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.22 ethambutol
embA 4244945 c.1713C>G synonymous_variant 0.19 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.17 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.18 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.18 ethambutol
embB 4247536 c.1023C>G synonymous_variant 0.2 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.19 ethambutol
embB 4247543 c.1030_1031delAGinsTC synonymous_variant 0.19 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.19 ethambutol
embB 4247555 p.Leu348Ile missense_variant 0.19 ethambutol
embB 4247563 p.Met350Ile missense_variant 0.19 ethambutol
embB 4247566 c.1053C>G synonymous_variant 0.19 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.19 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.18 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embB 4247609 p.Ser366Thr missense_variant 0.16 ethambutol
embB 4247626 c.1113C>T synonymous_variant 0.18 ethambutol
embB 4247630 p.Leu373Phe missense_variant 0.18 ethambutol
embB 4247635 c.1122G>C synonymous_variant 0.18 ethambutol
embB 4247646 p.Glu378Ala missense_variant 0.21 ethambutol Not assoc w R
embB 4248035 p.Val508Ile missense_variant 0.22 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.21 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.22 ethambutol
embB 4248052 c.1539G>C synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embB 4248055 c.1542G>C synonymous_variant 0.21 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.23 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.24 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.27 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.25 ethambutol
embB 4248121 c.1608G>A synonymous_variant 0.25 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.25 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.24 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.23 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.23 ethambutol
embB 4248149 p.Thr546Cys missense_variant 0.23 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embB 4248173 p.Val554Met missense_variant 0.22 ethambutol
embB 4248190 c.1677G>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embB 4248199 c.1686A>G synonymous_variant 0.19 ethambutol
embB 4248202 c.1689T>C synonymous_variant 0.18 ethambutol
embB 4248203 p.Pro564Ala missense_variant 0.18 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.18 ethambutol Uncertain significance
embB 4248215 p.Arg568Ser missense_variant 0.19 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.19 ethambutol
embB 4248225 p.Ala571Val missense_variant 0.19 ethambutol Uncertain significance
whiB6 4338593 c.-73delT upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
whiB6 4338596 c.-75G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin