TB-Profiler result

Run: ERR176643
Summary

Run ID: ERR176643

Sample name:

Date: 2024-04-14T13:54:03.123965

Number of reads: 514838

Percentage reads mapped: 19.56

Median coverage: 9.0

Strain: La3;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.2.2 West-Africa 2 RD702 0.06
La1.2.BCG M.bovis None 0.13
lineage4 Euro-American None 0.89
lineage4.9 Euro-American (H37Rv-like) None 0.92
La3 M.orygis None 0.1
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.787_789delGACinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.796_798delATCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2269_2271delGCGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491569 c.787_789delGACinsCT frameshift_variant&missense_variant 0.5 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491578 c.796_798delATCinsCG frameshift_variant&missense_variant 0.5 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305199 c.2269_2271delGCGinsTC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.89 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 558 c.558G>C synonymous_variant 0.67 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.7 isoniazid
dnaA 597 c.597C>G synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>G synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.75 isoniazid
dnaA 645 c.645A>T synonymous_variant 1.0 isoniazid
dnaA 652 c.652_654delCTAinsTG frameshift_variant&stop_gained 1.0 isoniazid Uncertain significance
dnaA 660 c.660G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 1.0 isoniazid
dnaA 669 c.669C>T synonymous_variant 1.0 isoniazid
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>A synonymous_variant 1.0 isoniazid
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 693 c.693A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 711 c.711C>G synonymous_variant 0.96 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.91 isoniazid
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.9 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.93 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.79 isoniazid
dnaA 945 c.945G>A synonymous_variant 1.0 isoniazid
dnaA 1050 c.1050G>T synonymous_variant 0.62 isoniazid
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1065 c.1065C>T synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.54 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.46 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.54 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.92 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.62 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.69 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 1.0 isoniazid
dnaA 1239 c.1239G>C synonymous_variant 0.38 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.62 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.64 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>G synonymous_variant 0.65 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.57 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 1.0 isoniazid
dnaA 1311 c.1311C>T synonymous_variant 0.47 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>C synonymous_variant 1.0 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1416 c.1416C>G synonymous_variant 1.0 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.65 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.65 isoniazid
dnaA 1440 c.1440C>T synonymous_variant 0.65 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 1.0 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 1.0 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.79 isoniazid
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.76 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.44 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.57 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.9 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6262 c.1023G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6355 c.-947G>A upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6397 c.1158G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6412 c.-890G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6688 c.-614C>A upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.65 levofloxacin Uncertain significance
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 6803 c.-499C>T upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6889 c.-413G>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7162 c.1923C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7347 p.Glu16Gln missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7445 c.144C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7508 c.207C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7577 c.276C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7592 c.291G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7853 c.552C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8228 c.927G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8337 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.76 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.76 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8369 c.1068G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8492 c.1191G>A synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8537 p.Glu412Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8570 c.1269G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Arg missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8849 c.1548C>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8963 c.1662C>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 0.84 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9110 c.1809G>A synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9122 c.1821C>T synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9134 c.1833C>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9184 p.Arg628Gln missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>A synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9203 c.1902G>A synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9263 c.1962C>T synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9267 p.Asn656Gly missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9318 c.2017C>T synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9329 c.2028C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13879 c.-321T>G upstream_gene_variant 0.82 isoniazid
Rv0010c 13884 c.-326A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13891 c.-335_-333delTCGinsGT upstream_gene_variant 0.8 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.88 isoniazid
fgd1 490797 c.15G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490858 p.Ala26Thr missense_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490984 c.202C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>T synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491052 c.270C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491070 c.288G>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491083 p.Val101Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491088 c.306C>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491110 p.Ala110Ser missense_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491124 c.342C>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491160 c.378G>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491560 p.His260Thr missense_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491568 c.786C>T synonymous_variant 0.5 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574640 c.-708G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.8 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574715 c.-633C>G upstream_gene_variant 0.9 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 0.9 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.5 ethionamide
isoniazid
mshA 575692 c.345G>C synonymous_variant 0.58 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.47 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.6 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.81 ethionamide
isoniazid
mshA 575764 c.417C>T synonymous_variant 0.81 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.94 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.88 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.84 ethionamide
isoniazid
mshA 575818 c.471G>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>A synonymous_variant 0.78 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.64 ethionamide
isoniazid
mshA 575860 c.513G>T synonymous_variant 0.38 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 0.64 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576193 c.846T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576197 c.850C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576202 c.855T>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 576211 c.864C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576215 c.868T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576233 c.886_888delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576247 c.900A>G synonymous_variant 1.0 ethionamide
isoniazid
ccsA 619528 c.-363C>A upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619618 c.-273C>G upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>G upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620157 c.267G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620313 c.423G>A synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.35 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.59 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>G synonymous_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620454 c.564C>T synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 0.9 capreomycin
amikacin
kanamycin
Rv0565c 656031 c.1440A>G synonymous_variant 1.0 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656085 c.1386A>G synonymous_variant 1.0 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 1.0 ethionamide
Rv0565c 656112 c.1359C>G synonymous_variant 1.0 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.9 ethionamide
Rv0565c 656502 c.967_969delCACinsAA frameshift_variant&missense_variant 0.92 ethionamide Uncertain significance
Rv0565c 656511 p.His320Gln missense_variant 1.0 ethionamide
Rv0565c 656533 c.937_938delCGinsAGA frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656535 c.936C>G synonymous_variant 1.0 ethionamide
Rv0565c 656539 c.931delA frameshift_variant 1.0 ethionamide Uncertain significance
Rv0565c 656559 c.912C>T synonymous_variant 1.0 ethionamide
Rv0565c 656571 c.900C>T synonymous_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657608 c.-138C>G upstream_gene_variant 0.67 ethionamide
Rv0565c 657620 c.-150C>T upstream_gene_variant 0.68 ethionamide
Rv0565c 657626 c.-156C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.68 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.73 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.73 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.66 ethionamide
Rv0565c 657680 c.-210G>A upstream_gene_variant 0.66 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 0.93 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.96 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.97 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.89 ethionamide
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.78 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.72 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.72 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.69 isoniazid
hadA 731817 c.-113C>A upstream_gene_variant 0.31 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732214 c.285A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
hadA 732226 c.297G>C synonymous_variant 0.92 isoniazid
hadA 732247 c.318C>T synonymous_variant 0.67 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.95 isoniazid
hadA 732265 c.336G>C synonymous_variant 0.39 isoniazid
hadA 732268 c.339T>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
hadA 732269 p.Glu114Met missense_variant 0.35 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.94 isoniazid
hadA 732301 c.372G>A synonymous_variant 0.79 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.79 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.81 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.97 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.97 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.97 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 0.98 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.94 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.95 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.72 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.93 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.93 isoniazid
nusG 734072 c.-182C>G upstream_gene_variant 0.73 rifampicin
nusG 734078 c.-176C>A upstream_gene_variant 1.0 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 1.0 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.75 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.76 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734123 c.-131C>T upstream_gene_variant 0.7 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 1.0 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.71 rifampicin
nusG 734135 c.-119G>T upstream_gene_variant 0.71 rifampicin
nusG 734144 c.-110G>T upstream_gene_variant 0.72 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734222 c.-31_-27delGGCTC upstream_gene_variant 1.0 rifampicin
nusG 734229 c.-25A>C upstream_gene_variant 1.0 rifampicin
nusG 734247 c.-7_-6delGAinsC upstream_gene_variant 1.0 rifampicin
nusG 734275 p.Thr8Pro missense_variant 1.0 rifampicin
nusG 734362 p.Ala37Thr missense_variant 0.73 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.72 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.73 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.71 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.74 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.78 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.75 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734520 c.267C>G synonymous_variant 0.78 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734631 c.378G>C synonymous_variant 1.0 rifampicin
nusG 734637 c.384G>C synonymous_variant 1.0 rifampicin
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734733 c.480T>C synonymous_variant 1.0 rifampicin
nusG 734750 p.Ser166Thr missense_variant 0.58 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.54 rifampicin
nusG 734771 p.Ala173Val missense_variant 0.5 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.47 rifampicin
nusG 734792 p.Val180Ala missense_variant 0.53 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.53 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.55 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.62 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.41 rifampicin
nusG 734877 c.624C>T synonymous_variant 0.5 rifampicin
nusG 734882 p.Ala210Gly missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
rpoB 760088 c.282C>G synonymous_variant 0.71 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.96 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.78 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.82 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.82 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.85 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.84 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 0.84 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760451 c.645C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>G synonymous_variant 0.83 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>T synonymous_variant 0.79 rifampicin
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760589 c.783C>G synonymous_variant 0.77 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 1.0 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.86 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760784 c.978G>C synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 0.87 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>T synonymous_variant 0.92 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 0.95 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.92 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>A synonymous_variant 0.76 rifampicin
rpoB 761207 c.1401C>G synonymous_variant 0.73 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.8 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761286 c.1480C>T synonymous_variant 0.86 rifampicin
rpoB 761289 p.Ser495Ala missense_variant 0.83 rifampicin
rpoB 761292 p.Val496Thr missense_variant 0.82 rifampicin
rpoB 761297 c.1491C>T synonymous_variant 0.8 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>A synonymous_variant 1.0 rifampicin
rpoB 761345 c.1539G>T synonymous_variant 0.82 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761358 c.1552_1554delGTTinsAC frameshift_variant&missense_variant 0.77 rifampicin
rpoB 761373 p.Val523His missense_variant 0.79 rifampicin
rpoB 761408 c.1602G>A synonymous_variant 0.32 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 0.43 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.66 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.39 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.71 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761651 c.1845C>T synonymous_variant 0.68 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>G synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.67 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.62 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.62 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762095 c.2289C>T synonymous_variant 0.85 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762138 c.2332C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>G synonymous_variant 0.93 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>T synonymous_variant 0.92 rifampicin
rpoB 762233 c.2427G>T synonymous_variant 0.87 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>A synonymous_variant 0.88 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.93 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.84 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.97 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.81 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 0.71 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 0.71 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.88 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 0.89 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 1.0 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.9 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 0.89 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoC 762818 c.-552C>A upstream_gene_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.78 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.79 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.77 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763178 c.-192G>C upstream_gene_variant 0.75 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 0.78 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.84 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.8 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.76 rifampicin
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763495 c.126G>A synonymous_variant 0.88 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 1.0 rifampicin
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.82 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>A synonymous_variant 0.75 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.98 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.83 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.84 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.97 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.97 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.97 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.96 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763831 c.462A>G synonymous_variant 0.92 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.94 rifampicin
rpoC 763853 c.484_486delGTCinsAT frameshift_variant&missense_variant 0.91 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.76 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.56 rifampicin
rpoC 763949 c.580_582delCGGinsAC frameshift_variant&missense_variant 0.57 rifampicin
rpoC 763960 c.591T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763972 c.603C>T synonymous_variant 0.4 rifampicin
rpoC 763978 c.609C>G synonymous_variant 0.56 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.38 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.47 rifampicin
rpoC 764002 c.633C>T synonymous_variant 0.55 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.95 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.94 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.67 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.67 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.96 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.93 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.96 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.67 rifampicin
rpoC 764110 c.741C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.98 rifampicin
rpoC 764159 c.790C>T synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Thr missense_variant 0.84 rifampicin
rpoC 764198 c.829C>T synonymous_variant 0.84 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.97 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.97 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.82 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>T synonymous_variant 0.82 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.84 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.97 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.74 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.97 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.74 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.97 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.67 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.94 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 1.0 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764593 c.1224C>A synonymous_variant 0.79 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>A synonymous_variant 0.78 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.85 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764959 c.1590G>A synonymous_variant 0.84 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764971 c.1602C>T synonymous_variant 0.77 rifampicin
rpoC 764995 c.1626C>G synonymous_variant 0.73 rifampicin Not assoc w R
rpoC 765005 c.1637_1638insGC frameshift_variant 1.0 rifampicin
rpoC 765010 p.Leu547Phe missense_variant 0.68 rifampicin
rpoC 765011 p.Ser548Gly missense_variant 0.71 rifampicin
rpoC 765014 c.1646_1647delCC frameshift_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>T synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.91 rifampicin
rpoC 765310 c.1941G>A synonymous_variant 0.86 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765352 c.1983G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765370 c.2001G>A synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765371 c.2002C>T synonymous_variant 0.81 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.79 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.82 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>T synonymous_variant 0.84 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.81 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.79 rifampicin
rpoC 765583 c.2214G>C synonymous_variant 0.78 rifampicin
rpoC 765613 p.His748Gln missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.77 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.86 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.84 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.84 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.81 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.81 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.76 rifampicin
rpoC 766061 c.2692_2694delGTCinsCG frameshift_variant&missense_variant 0.75 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766087 c.2718C>G synonymous_variant 0.77 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766097 p.Leu910Val missense_variant 0.77 rifampicin
rpoC 766108 c.2739C>T synonymous_variant 0.79 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766147 c.2778C>T synonymous_variant 0.82 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.82 rifampicin Uncertain significance
rpoC 766294 c.2925C>T synonymous_variant 0.9 rifampicin
rpoC 766312 c.2943T>G synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.76 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.75 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766435 c.3066G>A synonymous_variant 0.72 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.74 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 1.0 rifampicin
rpoC 766477 c.3108G>A synonymous_variant 0.75 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 0.75 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.75 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>T synonymous_variant 0.69 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.97 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.96 rifampicin
rpoC 766540 c.3171C>T synonymous_variant 0.36 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.97 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.97 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.79 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.82 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.97 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.89 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.98 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.98 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.98 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766813 c.3444G>C synonymous_variant 0.77 rifampicin
rpoC 766861 c.3492G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.89 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766978 c.3609C>A synonymous_variant 0.88 rifampicin
rpoC 766996 c.3627C>A synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.74 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>G synonymous_variant 1.0 rifampicin
rpoC 767212 c.3843G>C synonymous_variant 0.73 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.69 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.69 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775912 c.2569C>A synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 775913 c.2568C>G synonymous_variant 0.33 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775922 c.2559G>C synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.95 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 776036 c.2445G>A synonymous_variant 0.86 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.94 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.87 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.87 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.97 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.84 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.97 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.76 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.78 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.97 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.82 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.97 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.97 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.82 streptomycin
rpsL 781772 c.213C>G synonymous_variant 0.82 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>G synonymous_variant 0.93 streptomycin
rpsL 781817 c.258G>A synonymous_variant 1.0 streptomycin
rpsL 781820 c.261G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.81 streptomycin
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781853 c.294C>T synonymous_variant 0.73 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.71 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.65 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.62 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.42 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.97 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.96 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.98 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.98 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.8 linezolid
rplC 800594 c.-215C>T upstream_gene_variant 0.83 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.87 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.98 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.86 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.97 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.98 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.87 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.98 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.91 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.91 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.93 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.93 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>C upstream_gene_variant 1.0 linezolid
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.64 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 0.92 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 801136 p.Ser110Gly missense_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801150 c.342G>C synonymous_variant 0.86 linezolid
rplC 801153 c.345G>C synonymous_variant 0.86 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801195 c.387G>C synonymous_variant 0.77 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801249 c.441T>C synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 0.89 linezolid
rplC 801282 c.474G>T synonymous_variant 0.91 linezolid
rplC 801309 c.501C>G synonymous_variant 0.91 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801321 c.513C>T synonymous_variant 0.85 linezolid Not assoc w R - Interim
rplC 801323 p.Asn172Ser missense_variant 0.85 linezolid
rplC 801327 c.519C>T synonymous_variant 0.85 linezolid
rplC 801339 c.531T>C synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801420 c.612A>G synonymous_variant 0.8 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801427 p.Met207Val missense_variant 0.8 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
rplC 801442 p.Ile212Val missense_variant 0.8 linezolid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 0.74 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303479 c.549G>A synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303542 c.612C>G synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303647 c.717G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303716 c.786C>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303785 c.855G>A synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303812 c.882C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303821 c.891C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303935 c.1005G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303938 c.1008C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304778 c.1848T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304796 c.1866G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304904 c.1974G>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304988 c.2058G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 0.82 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305222 c.2292C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305279 p.His783Gln missense_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305348 c.2418C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305349 c.2419C>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305430 p.Val834Ile missense_variant 0.91 clofazimine
pretomanid
delamanid
sigE 1365015 c.603G>C synonymous_variant 0.9 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.92 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 1.0 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 1.0 pyrazinamide
sigE 1365075 c.663G>A synonymous_variant 1.0 pyrazinamide
sigE 1365081 c.669G>C synonymous_variant 1.0 pyrazinamide
sigE 1365084 c.672G>T synonymous_variant 1.0 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 1.0 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 1.0 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 1.0 pyrazinamide
sigE 1365111 c.699C>T synonymous_variant 1.0 pyrazinamide
atpE 1460816 c.-229T>C upstream_gene_variant 0.91 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>C upstream_gene_variant 1.0 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 1.0 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460915 c.-130C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460918 c.-127A>C upstream_gene_variant 1.0 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.88 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461194 c.150C>T synonymous_variant 0.84 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1473981 n.324_325insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474036 n.379G>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474104 n.447G>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474110 n.453A>G non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475201 n.1544G>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673490 c.-712A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673499 c.-703T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673502 c.-700C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673505 c.-697A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673535 c.-667A>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673541 c.-661G>A upstream_gene_variant 0.86 ethionamide
isoniazid Uncertain significance
inhA 1673547 c.-655T>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.92 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 0.92 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 1.0 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 1.0 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673682 c.-520G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1673710 p.Leu91Ile missense_variant 1.0 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673763 c.-439C>G upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673799 c.-403T>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673934 c.-268C>T upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.91 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 1.0 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 0.82 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674084 c.-118C>G upstream_gene_variant 0.83 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674368 p.Ala56Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674375 c.174C>G synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674382 p.Leu61Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674501 c.300G>A synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.81 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.81 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674636 c.435C>G synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674669 c.468G>T synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674672 c.471C>T synonymous_variant 0.9 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674690 c.489C>G synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCA frameshift_variant&missense_variant 0.93 ethionamide
isoniazid
inhA 1674729 c.528G>A synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674738 c.537C>G synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674746 p.Tyr182Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674813 c.612C>T synonymous_variant 0.77 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.75 ethionamide
isoniazid
inhA 1674840 c.639C>G synonymous_variant 0.75 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674849 c.648G>A synonymous_variant 0.7 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.74 ethionamide
isoniazid
inhA 1674873 c.672G>A synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674934 c.733C>T synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674939 c.738G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674966 c.765T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 0.91 ethionamide
isoniazid
rpsA 1833489 c.-53T>A upstream_gene_variant 1.0 pyrazinamide
rpsA 1833495 c.-46_-45delCC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.89 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.81 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
rpsA 1833721 c.180A>G synonymous_variant 0.78 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833772 c.231C>T synonymous_variant 0.82 pyrazinamide
rpsA 1833782 p.Ser81Thr missense_variant 0.83 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.81 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.93 pyrazinamide
rpsA 1833844 c.303C>T synonymous_variant 0.92 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833901 c.360G>A synonymous_variant 0.91 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.84 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.78 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.8 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.85 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.81 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834192 c.651C>T synonymous_variant 0.58 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.73 pyrazinamide
rpsA 1834213 c.672G>A synonymous_variant 0.74 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 0.83 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 0.66 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 0.63 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.66 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 0.71 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.82 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834477 c.936C>G synonymous_variant 0.81 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 0.83 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.84 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834570 c.1029C>T synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
rpsA 1834606 c.1065C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 0.95 linezolid
tsnR 1853361 c.-245T>C upstream_gene_variant 0.95 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.96 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 0.88 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.96 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.96 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.97 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.96 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.95 linezolid
tsnR 1853441 c.-165C>T upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
bacA 2063254 p.Glu492Ala missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063259 p.Glu490Asp missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063265 p.Gly488Glu missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063271 c.1458G>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063275 p.His485Cys missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063280 c.1449C>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063289 c.1440A>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063292 c.1437C>T synonymous_variant 0.91 streptomycin
kanamycin Not assoc w R - Interim
capreomycin
amikacin
bacA 2063295 c.1434C>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063538 c.1191A>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063541 c.1188A>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063544 c.1185C>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063553 c.1176G>T synonymous_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063556 c.1173T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063565 c.1164C>T synonymous_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063588 c.1141T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063610 c.1117_1119delTCCinsGA frameshift_variant&stop_gained 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063613 c.1116T>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063625 c.1104G>T synonymous_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063628 c.1101C>G synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063640 p.Asp363Ala missense_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101744 p.Asp433Glu missense_variant 0.54 ethionamide
delamanid
isoniazid
ndh 2101756 c.1287G>C synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2101762 c.1281C>T synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2101765 c.1278C>G synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.92 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101795 c.1248G>C synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101808 p.Thr412Ser missense_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2101830 p.Ile405Val missense_variant 0.53 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101966 c.1077T>G synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101993 c.1050A>G synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>T synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2102230 c.813G>T synonymous_variant 0.83 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.71 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102239 c.804C>T synonymous_variant 0.68 ethionamide
delamanid
isoniazid
ndh 2102244 c.799C>A synonymous_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102254 c.789C>T synonymous_variant 0.3 ethionamide
delamanid
isoniazid
ndh 2102275 c.768C>G synonymous_variant 0.77 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102334 p.Gln237Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102337 c.706T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155659 c.453C>G synonymous_variant 0.54 isoniazid
pncA 2289930 c.-689A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289937 c.-696C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289945 c.-704T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289958 c.-717T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289964 c.-723C>A upstream_gene_variant 1.0 pyrazinamide
pncA 2289967 c.-726C>A upstream_gene_variant 1.0 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.88 pyrazinamide
kasA 2517926 c.-189G>A upstream_gene_variant 0.95 isoniazid
kasA 2517956 c.-159G>A upstream_gene_variant 1.0 isoniazid
kasA 2517965 c.-150C>T upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.94 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.94 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.8 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.94 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.96 isoniazid
kasA 2518183 c.69G>T synonymous_variant 0.97 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.97 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.93 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.92 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.95 isoniazid
kasA 2518265 p.Val51Ile missense_variant 0.82 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.46 isoniazid
kasA 2518475 c.361A>C synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518513 c.399C>G synonymous_variant 0.58 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518537 c.423C>G synonymous_variant 0.53 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.56 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518579 c.465T>A synonymous_variant 1.0 isoniazid
kasA 2518582 c.468G>T synonymous_variant 0.56 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.59 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518618 c.504G>T synonymous_variant 0.68 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.67 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.61 isoniazid
kasA 2518645 c.531G>A synonymous_variant 0.65 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.73 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.81 isoniazid
kasA 2518696 c.582C>G synonymous_variant 1.0