Run ID: SRR14801749
Sample name:
Date: 2024-04-15T14:56:40.077876
Number of reads: 398453
Percentage reads mapped: 12.02
Median coverage: 2.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.94 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | c.451_453delGTCinsCG | Assoc w R | High-level resistance |
| c.343_345delATCinsGG | Assoc w R | High-level resistance | ||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.766_768delGCTinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| fbiC | c.1189_1191delAAAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 491548 | c.766_768delGCTinsCC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1304119 | c.1189_1191delAAAinsCG | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| katG | 2155659 | c.451_453delGTCinsCG | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
| katG | 2155767 | c.343_345delATCinsGG | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 741 | c.741T>C | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
| dnaA | 756 | c.756T>C | synonymous_variant | 0.9 | isoniazid | |
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6706 | c.-596G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6715 | c.1476C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6727 | c.-575G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7135 | c.-167G>A | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7153 | c.-149G>T | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7159 | c.1920C>T | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7165 | c.-137C>A | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7168 | c.-134C>T | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7210 | p.Asp657Glu | missense_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7213 | c.-89G>A | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7225 | c.-77T>C | upstream_gene_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7397 | c.96G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7421 | c.120G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7424 | c.123G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7436 | c.135C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7517 | c.216G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7520 | c.219G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7553 | c.252C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7569 | p.Ala90Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7614 | c.313C>T | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7725 | c.424C>T | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7754 | p.Asp151Glu | missense_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7787 | c.486G>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7790 | c.489G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7826 | c.525C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7829 | c.528C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7847 | c.546G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7853 | c.552C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8174 | c.873C>G | synonymous_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 0.87 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8228 | c.927G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8235 | c.934T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8240 | c.939C>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8246 | c.945C>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8247 | c.946_948delATCinsGG | frameshift_variant&missense_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8253 | p.Ile318Leu | missense_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8270 | c.969G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8273 | c.972C>G | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8279 | c.978G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8366 | c.1065G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8372 | c.1071G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8390 | c.1089C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8396 | c.1095C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8401 | p.Asp367Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8405 | c.1104C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8421 | c.1120_1122delGTGinsAC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8433 | p.Thr378Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8442 | c.1141C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8492 | c.1191G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8501 | c.1200G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8513 | c.1212C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8535 | p.Glu412Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | p.Asp415Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8573 | c.1272G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8813 | p.Asp504Glu | missense_variant | 0.8 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8825 | c.1524G>A | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8846 | c.1545C>T | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8849 | c.1548C>G | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 0.82 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 0.84 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>G | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8900 | c.1599G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8967 | p.Ala556Asn | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9236 | c.1935G>C | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.91 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9258 | c.1957C>T | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9263 | c.1962C>T | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9275 | c.1974G>A | synonymous_variant | 0.88 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 0.95 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9314 | c.2013G>C | synonymous_variant | 0.89 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9324 | c.2023_2025delTCGinsAGT | synonymous_variant | 0.86 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9341 | c.2040C>G | synonymous_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9353 | c.2052G>C | synonymous_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9362 | c.2061C>T | synonymous_variant | 0.86 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9374 | c.2073G>C | synonymous_variant | 0.86 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 0.86 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>G | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9386 | c.2085T>G | synonymous_variant | 0.79 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9398 | c.2097T>C | synonymous_variant | 0.77 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491563 | c.781_783delAGCinsTCG | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491574 | c.792C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491604 | c.822G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491649 | c.867C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491655 | c.873C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575710 | c.363C>T | synonymous_variant | 0.8 | ethionamide | |
| isoniazid | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 0.8 | ethionamide | |
| isoniazid | ||||||
| mshA | 575732 | c.385_387delCTTinsTG | frameshift_variant&missense_variant | 0.92 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575744 | p.Ala133Thr | missense_variant | 0.93 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 575749 | c.402C>G | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Thr | missense_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| mshA | 575788 | c.441C>T | synonymous_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| mshA | 575795 | p.Ile150Val | missense_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| mshA | 575800 | c.453G>T | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575845 | c.498C>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 0.87 | ethionamide | |
| isoniazid | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 0.82 | ethionamide | |
| isoniazid | ||||||
| mshA | 575881 | c.534C>T | synonymous_variant | 0.8 | ethionamide | |
| isoniazid | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 0.8 | ethionamide | |
| isoniazid | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 0.8 | ethionamide | |
| isoniazid | ||||||
| ccsA | 620337 | c.447C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620346 | c.456C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620358 | c.468C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620362 | p.Ala158Ser | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620418 | c.528G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620436 | c.546T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620439 | c.549T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620454 | c.564C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620598 | c.708C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620605 | c.715_717delGTTinsAC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620619 | c.729G>C | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| nusG | 734415 | c.162C>T | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734424 | c.171G>T | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 0.96 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 0.96 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 0.96 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| nusG | 734484 | c.231C>T | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734499 | c.246G>C | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 0.76 | rifampicin | |
| nusG | 734571 | c.318C>G | synonymous_variant | 0.75 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760088 | c.282C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760104 | c.298_300delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>T | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760235 | c.429T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760244 | c.438G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760316 | c.510C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760317 | c.511_512delAGinsTC | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760325 | c.519G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760331 | c.525G>T | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760334 | c.528G>T | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760355 | p.Glu183Asp | missense_variant | 0.89 | rifampicin | |
| rpoB | 760357 | p.Thr184Ser | missense_variant | 0.9 | rifampicin | Uncertain significance |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.91 | rifampicin | Uncertain significance |
| rpoB | 760406 | c.600G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 0.94 | rifampicin | Uncertain significance |
| rpoB | 760415 | c.609C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760457 | c.651C>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760460 | c.654G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760478 | c.672C>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>T | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 760499 | c.693G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760502 | c.696C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760508 | c.702G>A | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760520 | c.714C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760535 | c.729C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760561 | c.757_758delCG | frameshift_variant | 0.92 | rifampicin | |
| rpoB | 760567 | p.Ser254Trp | missense_variant | 0.92 | rifampicin | |
| rpoB | 760568 | c.762_763insGC | frameshift_variant | 0.92 | rifampicin | |
| rpoB | 760571 | c.765G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760574 | c.768G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 760585 | p.Asn260Ser | missense_variant | 0.92 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.92 | rifampicin | |
| rpoB | 760595 | c.789C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760596 | p.Thr264Pro | missense_variant | 0.92 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760721 | c.915C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760730 | c.924T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760748 | c.942C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760751 | c.945G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760755 | c.949_951delCATinsAC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
| rpoB | 760759 | p.Val318Ala | missense_variant | 0.97 | rifampicin | |
| rpoB | 760764 | p.Glu320Gln | missense_variant | 0.97 | rifampicin | |
| rpoB | 760769 | c.963C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760784 | c.978G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760787 | c.981G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760808 | c.1002C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760829 | c.1023C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760838 | c.1032G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760859 | c.1053T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760877 | c.1071G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760883 | c.1077G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760887 | p.Thr361Val | missense_variant | 0.95 | rifampicin | Uncertain significance |
| rpoB | 760910 | c.1104C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760916 | c.1110C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 760919 | c.1113C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760964 | c.1158C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760965 | c.1159_1161delATGinsCC | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoB | 760970 | c.1164G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760973 | c.1167G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760988 | c.1182C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760997 | c.1191G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761054 | c.1248G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761063 | c.1257C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761147 | c.1341C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761217 | c.1411_1413delCCGinsTC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761220 | c.1414_1416delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761288 | c.1482G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761300 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761318 | c.1512G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761345 | c.1539G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761346 | p.Val514Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761361 | c.1555_1556delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761367 | p.Glu521Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761374 | p.Val523Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 761552 | c.1746G>T | synonymous_variant | 0.87 | rifampicin | |
| rpoB | 761555 | c.1749G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>C | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761669 | c.1863C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761682 | c.1876C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761687 | c.1881C>T | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761708 | c.1902C>T | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761712 | p.Val636Ile | missense_variant | 0.93 | rifampicin | |
| rpoB | 761718 | c.1912_1913delGCinsT | frameshift_variant&missense_variant | 0.92 | rifampicin | |
| rpoB | 761722 | p.Glu639Gly | missense_variant | 0.85 | rifampicin | Uncertain significance |
| rpoB | 761727 | p.Ser641Gly | missense_variant | 0.93 | rifampicin | |
| rpoB | 761729 | c.1925dupG | frameshift_variant | 0.92 | rifampicin | |
| rpoB | 761736 | p.Ile644Val | missense_variant | 0.93 | rifampicin | Uncertain significance |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761753 | c.1947C>G | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 0.93 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 0.93 | rifampicin | |
| rpoB | 761784 | p.Thr660Ser | missense_variant | 0.96 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 0.97 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 761837 | c.2031C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761847 | c.2041_2043delTGCinsCT | frameshift_variant&missense_variant | 0.92 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 761867 | c.2061C>G | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761868 | c.2062_2064delGACinsCG | frameshift_variant&missense_variant | 0.88 | rifampicin | |
| rpoB | 761873 | c.2067A>T | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 761892 | p.Ile696Val | missense_variant | 0.9 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 0.92 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 0.92 | rifampicin | |
| rpoB | 761921 | c.2115C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761999 | c.2193G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 762002 | c.2196C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 762038 | c.2232C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762047 | c.2241G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762137 | c.2331C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762245 | c.2439G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 762284 | c.2478G>T | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762293 | c.2487T>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762308 | c.2502G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 762314 | c.2508C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 762341 | c.2535G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 762350 | c.2544C>G | synonymous_variant | 0.87 | rifampicin | |
| rpoB | 762353 | c.2547C>T | synonymous_variant | 0.87 | rifampicin | |
| rpoB | 762359 | c.2553C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.93 | rifampicin | |
| rpoB | 762368 | c.2562G>A | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762374 | c.-996G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762866 | c.3060C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762879 | c.3073_3075delATGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 762911 | c.-459C>T | upstream_gene_variant | 0.97 | rifampicin | |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 762959 | c.3153G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.97 | rifampicin | |
| rpoB | 762989 | c.3183G>A | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 763004 | c.3198G>A | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 763007 | c.3201C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763022 | c.-348C>G | upstream_gene_variant | 0.97 | rifampicin | |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 763053 | c.3247T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763076 | c.-294C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763088 | c.3282C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763103 | c.-267G>C | upstream_gene_variant | 0.98 | rifampicin | |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 763130 | c.3324G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763133 | c.-237G>C | upstream_gene_variant | 0.98 | rifampicin | |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763160 | c.-210G>T | upstream_gene_variant | 0.96 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.95 | rifampicin | |
| rpoC | 763193 | c.-177C>T | upstream_gene_variant | 0.91 | rifampicin | |
| rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.88 | rifampicin | |
| rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.88 | rifampicin | |
| rpoC | 763208 | c.-162T>C | upstream_gene_variant | 0.88 | rifampicin | |
| rpoB | 763214 | c.3408T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 763227 | p.Leu1141Met | missense_variant | 0.86 | rifampicin | |
| rpoC | 763232 | c.-138C>T | upstream_gene_variant | 0.86 | rifampicin | |
| rpoB | 763235 | p.Glu1143Asp | missense_variant | 0.86 | rifampicin | |
| rpoB | 763241 | p.Glu1145Asp | missense_variant | 0.8 | rifampicin | |
| rpoC | 763259 | c.-111G>C | upstream_gene_variant | 0.8 | rifampicin | |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763423 | p.Glu18Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763430 | c.61_63delAGGinsCT | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoC | 763433 | c.64_66delCAAinsAC | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoC | 763443 | p.Tyr25Phe | missense_variant | 0.93 | rifampicin | |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763492 | c.123G>T | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763531 | c.162G>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>T | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763573 | c.204G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763699 | c.330G>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763709 | c.340C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763747 | c.378G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763765 | c.396T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763831 | c.462A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763837 | c.468G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763840 | c.471G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763867 | c.498C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763871 | p.Gly168Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763921 | c.552G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763933 | c.564C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763940 | p.Ala191Ser | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoC | 763945 | c.576T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 763947 | p.Ala193Val | missense_variant | 0.92 | rifampicin | Uncertain significance |
| rpoC | 763951 | c.582G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763960 | c.591T>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763978 | c.609C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763991 | p.Ile208Leu | missense_variant | 0.96 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764029 | p.Glu220Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764084 | p.Asn239Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 764089 | c.720C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764102 | p.Val245Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 764153 | p.Gln262Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 764161 | c.792G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764182 | p.Asp271Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764207 | p.Val280Thr | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoC | 764215 | c.846A>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764217 | p.Asn283Ser | missense_variant | 0.96 | rifampicin | |
| rpoC | 764227 | c.858G>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764239 | c.870T>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764254 | c.885G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764263 | c.894G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764287 | c.918C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764293 | c.924G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764297 | p.Met310Leu | missense_variant | 0.96 | rifampicin | |
| rpoC | 764311 | c.942C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764341 | c.972G>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764344 | c.975C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764353 | c.984G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764371 | c.1002G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764387 | c.1018T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 0.96 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764455 | c.1086G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764485 | c.1116G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764491 | c.1122G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764500 | c.1131C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764605 | c.1236G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764671 | c.1302G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764677 | c.1308C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764701 | c.1332C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764713 | c.1344G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764797 | c.1428G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764818 | c.1449G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764830 | c.1461C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764833 | c.1464A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764836 | c.1467G>A | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764839 | c.1470C>A | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764875 | c.1506C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765425 | p.Lys686Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765445 | c.2076G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765452 | p.Ala695Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765466 | c.2097C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765480 | p.Tyr704Phe | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765496 | c.2127C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765533 | p.Tyr722His | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765778 | c.2409C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765779 | c.2410_2412delGACinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765800 | p.Phe811Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765817 | c.2448G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765823 | c.2454C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765871 | c.2502T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765908 | c.2539C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765940 | c.2571A>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765946 | c.2577C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765947 | c.2578T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765952 | c.2583G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765961 | c.2592G>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765962 | c.2593T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 0.89 | rifampicin | |
| rpoC | 766027 | c.2658G>T | synonymous_variant | 0.88 | rifampicin | |
| rpoC | 766034 | p.His889Thr | missense_variant | 0.93 | rifampicin | |
| rpoC | 766042 | c.2673C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 0.92 | rifampicin | |
| rpoC | 766061 | p.Val898Ile | missense_variant | 0.9 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766390 | c.3021C>T | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 766393 | c.3024C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 766408 | c.3039C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 766428 | c.3059_3060insTAC | disruptive_inframe_insertion | 0.94 | rifampicin | |
| rpoC | 766433 | c.3065delA | frameshift_variant | 0.94 | rifampicin | |
| rpoC | 766442 | p.Thr1025Val | missense_variant | 0.95 | rifampicin | |
| rpoC | 766456 | c.3087C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766459 | c.3090G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766493 | p.Gly1042Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 766504 | c.3135G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766517 | c.3148_3150delACCinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766534 | c.3165C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766539 | c.3171_3174delCGGC | frameshift_variant | 1.0 | rifampicin | |
| rpoC | 766548 | c.3179_3180insACAA | frameshift_variant | 1.0 | rifampicin | |
| rpoC | 766554 | p.Tyr1062Phe | missense_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766579 | c.3210C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766594 | c.3225G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766702 | c.3333G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766720 | c.3351C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766732 | c.3363G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766741 | c.3372G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766807 | c.3438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766837 | c.3468G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766858 | c.3489C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766867 | c.3498C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766876 | c.3507C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766882 | c.3513C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | c.3514_3516delTCGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766909 | c.3540G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766911 | p.Ile1181Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766915 | p.Asp1182Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 767008 | c.3639G>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767020 | c.3651C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767023 | c.3654C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767068 | c.3699G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | c.3736_3738delAACinsCG | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 767162 | p.Asn1265Ala | missense_variant | 0.95 | rifampicin | |
| rpoC | 767167 | c.3798C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 767174 | p.Asn1269Asp | missense_variant | 0.95 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.95 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 767197 | c.3828G>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775793 | c.2688C>G | synonymous_variant | 0.94 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775796 | c.2683_2685delTTTinsAG | frameshift_variant&stop_gained | 0.94 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775814 | c.2667C>G | synonymous_variant | 0.84 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775817 | c.2664T>C | synonymous_variant | 0.95 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mmpL5 | 775826 | c.2655G>C | synonymous_variant | 0.88 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775829 | c.2652C>G | synonymous_variant | 0.71 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775832 | c.2647_2649delGCCinsTG | frameshift_variant&missense_variant | 0.9 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775835 | c.2646C>G | synonymous_variant | 0.71 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775838 | c.2643G>C | synonymous_variant | 0.71 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775851 | p.Ser877Thr | missense_variant | 0.76 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775856 | c.2625T>C | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775885 | p.Ile866Leu | missense_variant | 0.7 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775886 | c.2595A>T | synonymous_variant | 0.92 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775889 | c.2592C>G | synonymous_variant | 0.77 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775895 | c.2586C>A | synonymous_variant | 0.83 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775904 | c.2577G>A | synonymous_variant | 0.92 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775915 | p.Ala856Ser | missense_variant | 0.83 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775916 | c.2565T>C | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.81 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775951 | c.2530C>T | synonymous_variant | 0.75 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.56 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.53 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775970 | c.2511G>C | synonymous_variant | 0.47 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.94 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.94 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775991 | c.2490G>A | synonymous_variant | 0.85 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781595 | c.36T>C | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 0.92 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 0.92 | streptomycin | |
| rpsL | 781616 | c.57C>G | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781622 | c.63C>G | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781631 | c.72G>C | synonymous_variant | 0.94 | streptomycin | |
| rpsL | 781649 | c.90T>C | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781652 | c.93T>C | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 0.94 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 0.97 | streptomycin | Not assoc w R - Interim |
| rpsL | 781728 | c.169T>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781737 | p.Gln60Gly | missense_variant | 0.97 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 0.97 | streptomycin | Not assoc w R - Interim |
| rpsL | 781772 | c.213C>T | synonymous_variant | 0.97 | streptomycin | Not assoc w R - Interim |
| rpsL | 781814 | c.255C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781829 | c.270G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781841 | c.282C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781901 | c.342C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 0.97 | streptomycin | Uncertain significance |
| rplC | 800516 | c.-293G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800543 | c.-266C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800570 | c.-239C>G | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800574 | c.-235_-234delGTinsAC | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800579 | c.-230C>T | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800594 | c.-215C>G | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800597 | c.-212A>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800600 | c.-209G>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800603 | c.-206G>T | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800633 | c.-176T>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800642 | c.-167C>T | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800648 | c.-161A>G | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800678 | c.-131C>T | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800684 | c.-125G>A | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800702 | c.-107G>A | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800735 | c.-74C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
| fbiC | 1304013 | c.1083G>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304019 | c.1089C>T | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304049 | c.1119T>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304050 | c.1120T>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304058 | p.Glu376Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304066 | p.Ala379Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304070 | c.1140C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304079 | c.1149A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304097 | c.1167G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304118 | c.1188C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304127 | c.1197A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304136 | c.1206C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304475 | c.1545G>C | synonymous_variant | 0.8 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304481 | c.1551T>G | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304490 | c.1560C>A | synonymous_variant | 0.88 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304496 | c.1566T>G | synonymous_variant | 0.88 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304499 | c.1569T>G | synonymous_variant | 0.94 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304515 | p.Ala529Thr | missense_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304553 | c.1623C>G | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304556 | c.1626C>T | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304571 | c.1641G>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.89 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304671 | p.Val581Thr | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304682 | c.1752C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304715 | c.1785G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304739 | c.1809C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304757 | c.1827A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304769 | c.1839C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304772 | c.1842C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304830 | c.1900_1901delTCinsAG | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364778 | c.366G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364784 | c.372C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364802 | c.390C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364811 | c.399A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364814 | c.402C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364818 | c.406_408delCTAinsTG | frameshift_variant&stop_gained | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364865 | c.453G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364867 | p.Ala152Gly | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364877 | c.465G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364883 | c.471G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364913 | c.501C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364922 | p.Glu170Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364925 | c.513C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364950 | c.538_540delGCAinsTG | frameshift_variant&stop_gained | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364962 | c.550_552delCCTinsGC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364967 | c.555C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364970 | c.558G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364976 | c.564T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364980 | c.568T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364984 | p.Ala191Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364992 | c.580_582delCCGinsGC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1365000 | c.588G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1365003 | c.591T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365006 | c.594T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365018 | c.606G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365042 | c.630G>C | synonymous_variant | 0.9 | pyrazinamide | |
| rrs | 1471866 | n.21C>T | non_coding_transcript_exon_variant | 0.73 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471922 | n.78delT | non_coding_transcript_exon_variant | 0.89 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.89 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471931 | n.87delA | non_coding_transcript_exon_variant | 0.89 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.89 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 0.95 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472019 | n.174G>A | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472023 | n.178G>T | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472028 | n.183A>G | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472031 | n.186G>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472032 | n.187G>A | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472033 | n.188A>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472035 | n.190G>T | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472037 | n.192A>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472040 | n.195T>G | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472042 | n.197T>G | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Not assoc w R | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Not assoc w R | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472337 | n.492C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472380 | n.535G>C | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472755 | n.910G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472848 | n.1003T>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472859 | n.1014G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTC | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.95 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473696 | n.39T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473697 | n.40C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473699 | n.42A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473717 | n.60G>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473746 | n.89T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473811 | n.154C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1473823 | n.166T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1473833 | n.176G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473887 | n.230T>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1473888 | n.231T>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473922 | n.265A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1473923 | n.266C>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1473935 | n.278C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474135 | n.478G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474266 | n.609T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474284 | n.629dupC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474292 | n.635_644delTTCCTCTCCGinsC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474303 | n.646A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474306 | n.649A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.653_654delTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474413 | n.756_757delACinsTAT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474420 | n.764_769delGCGCAT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474428 | n.771C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474429 | n.772G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474430 | n.773C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474432 | n.775C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474438 | n.781delAinsGT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474439 | n.782A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474446 | n.789C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474629 | n.972G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474640 | n.983C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474677 | n.1020A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474710 | n.1053T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474711 | n.1054G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474712 | n.1055G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474713 | n.1056T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474716 | n.1059_1063delAAAGCinsCCAAGAAT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475061 | n.1404C>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475062 | n.1405A>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475120 | n.1463G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475353 | n.1696A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475354 | n.1697A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475363 | n.1706C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475378 | n.1721A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475379 | n.1722G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475380 | n.1723C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475397 | n.1740G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475398 | n.1741C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475399 | n.1742T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475479 | n.1822C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475603 | n.1946G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475615 | n.1958C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475618 | n.1961C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475626 | n.1969delTinsCC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475629 | n.1972G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475643 | n.1986C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475647 | n.1990G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475753 | n.2096C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475762 | n.2105G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475764 | n.2107A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475775 | n.2118G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1475991 | n.2334T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476032 | n.2375C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476105 | n.2448G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476540 | n.2883C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476665 | n.3008T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476679 | n.3022T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476725 | n.3068C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476731 | n.3074G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476746 | n.3089T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476747 | n.3090C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476754 | n.3097G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673505 | c.-697A>T | upstream_gene_variant | 0.83 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673523 | c.-679G>C | upstream_gene_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673526 | c.-676G>T | upstream_gene_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673541 | c.-661G>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673556 | c.-646C>G | upstream_gene_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673580 | c.-622T>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673596 | c.157_159delAAGinsGA | frameshift_variant&missense_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673615 | p.Glu59Val | missense_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673633 | p.Ser65Asn | missense_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673637 | p.Asp66Glu | missense_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673652 | c.-550C>G | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673657 | p.Thr73Lys | missense_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673660 | p.Ala74Glu | missense_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673691 | c.-511G>T | upstream_gene_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673709 | c.-493C>T | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673710 | c.271_273delCTAinsAC | frameshift_variant&missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673716 | p.Ala93Gln | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673730 | c.-472C>G | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673748 | c.-454A>G | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673749 | p.Lys104Arg | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673760 | p.Lys107Asn | missense_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673772 | c.-430C>G | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673799 | c.-403T>G | upstream_gene_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673808 | c.-394A>C | upstream_gene_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673829 | p.Asn130Lys | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673830 | p.Lys131Arg | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673838 | c.-364T>C | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673841 | c.-361A>G | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673844 | p.Met135Ile | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673847 | c.-355A>C | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673853 | c.-349A>C | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673856 | c.-346T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673865 | c.-337C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673870 | p.Ser144Met | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673901 | c.-301A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673904 | c.-298C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673905 | p.Ser156Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673916 | c.-286A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673917 | p.Val160Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673941 | p.Ala168Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673946 | c.-256C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673949 | c.-253G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673955 | c.-247G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833554 | p.Thr5Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833596 | p.Ser19Ala | missense_variant | 0.93 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1833628 | c.87G>C | synonymous_variant | 0.91 | pyrazinamide | |
| rpsA | 1833634 | c.93G>A | synonymous_variant | 0.92 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833664 | c.123C>A | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833685 | c.144G>T | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833709 | c.168C>T | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833724 | c.183C>T | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833730 | c.189C>T | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833733 | c.192C>T | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 0.93 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833808 | c.267G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833829 | c.288A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833877 | c.336C>T | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833970 | c.429G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833976 | c.435C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833991 | c.450C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834192 | c.651C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834231 | c.690T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834234 | c.693G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834279 | c.738C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834345 | c.804C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834361 | c.820T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834396 | c.855G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834520 | p.Ala327Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834554 | c.1014_1015delTG | frameshift_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834558 | c.1017_1018insAG | frameshift_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834606 | c.1065C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834774 | c.1233C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834776 | p.Ala412Glu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853375 | c.-231G>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853417 | c.-189G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.97 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.97 | linezolid | |
| tsnR | 1853441 | c.-165C>A | upstream_gene_variant | 0.97 | linezolid | |
| tsnR | 1853453 | c.-153G>C | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 0.94 | linezolid | |
| tsnR | 1853474 | c.-132C>G | upstream_gene_variant | 0.93 | linezolid | |
| tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853480 | c.-126G>C | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853481 | c.-125A>G | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853489 | c.-117C>T | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853490 | c.-116_-114delCCGinsGC | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853495 | c.-111G>C | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853516 | c.-90C>G | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853523 | c.-83_-82delCGinsAA | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853528 | c.-78G>C | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853531 | c.-75A>C | upstream_gene_variant | 0.92 | linezolid | |
| tsnR | 1853540 | c.-66A>G | upstream_gene_variant | 0.85 | linezolid | |
| tsnR | 1853552 | c.-54C>G | upstream_gene_variant | 0.69 | linezolid | |
| katG | 2155668 | c.444G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155674 | c.438G>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155677 | c.435C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155680 | c.432G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155696 | p.Ala139Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155737 | c.375C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155742 | p.Gly124Arg | missense_variant | 1.0 | isoniazid | |
| katG | 2155743 | c.369G>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155747 | p.Ala122Gly | missense_variant | 1.0 | isoniazid | |
| katG | 2155752 | c.360C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155764 | p.His116Gln | missense_variant | 1.0 | isoniazid | |
| katG | 2155782 | c.330C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155785 | c.327T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.94 | isoniazid | |
| kasA | 2517953 | c.-162C>T | upstream_gene_variant | 0.93 | isoniazid | |
| kasA | 2517959 | c.-156C>T | upstream_gene_variant | 0.92 | isoniazid | |
| kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.92 | isoniazid | |
| kasA | 2517968 | c.-147T>C | upstream_gene_variant | 0.91 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.91 | isoniazid | |
| kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.85 | isoniazid | |
| kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.81 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518633 | c.519G>A | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518636 | c.522C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518639 | c.525G>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518656 | p.Ala181Gly | missense_variant | 0.92 | isoniazid | |
| kasA | 2518663 | c.549T>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518688 | p.Val192Phe | missense_variant | 0.91 | isoniazid | |
| kasA | 2518696 | c.582C>T | synonymous_variant | 0.83 | isoniazid | |
| kasA | 2518697 | p.Cys195Val | missense_variant | 0.82 | isoniazid | |
| kasA | 2518708 | c.594C>G | synonymous_variant | 0.82 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 0.82 | isoniazid | |
| kasA | 2518715 | p.Pro201Gly | missense_variant | 0.82 | isoniazid | |
| kasA | 2518726 | c.612G>A | synonymous_variant | 0.89 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518756 | c.642G>T | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518779 | c.665_666insTCCC | frameshift_variant | 0.96 | isoniazid | |
| kasA | 2518783 | c.669T>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518788 | c.675_678delGGCC | frameshift_variant | 0.96 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518813 | c.699C>T | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518834 | c.720C>T | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518843 | c.729T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518847 | p.Leu245Met | missense_variant | 1.0 | isoniazid | |
| kasA | 2518853 | p.Leu247Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518867 | c.753G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518877 | p.Lys255Leu | missense_variant | 1.0 | isoniazid | |
| kasA | 2519041 | c.927C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519044 | c.930G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519056 | c.942G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519059 | c.945G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519062 | c.948T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519068 | c.954C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519072 | p.Ala320Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2519077 | c.963G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519098 | c.984C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519104 | c.990T>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519107 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519110 | p.Asp332Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2519111 | c.997_999delCAGinsAT | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2519122 | c.1008G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519131 | c.1017G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519137 | c.1023T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519146 | c.1032C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519158 | c.1044C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519183 | c.1069_1071delCTCinsTG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.88 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783499 | c.544T>C | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.89 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783506 | c.537C>T | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783509 | c.534C>G | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.85 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783526 | c.517C>T | synonymous_variant | 0.85 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.85 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.87 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.88 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.91 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>C | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783568 | p.Asn159His | missense_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783575 | c.468G>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783626 | c.415_417delGCGinsTC | frameshift_variant&missense_variant | 0.97 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783634 | p.Leu137Ile | missense_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783641 | c.402G>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783644 | c.399C>T | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783651 | p.His131Ala | missense_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783671 | p.Arg124His | missense_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783689 | c.354G>C | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783695 | c.348C>T | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2752c | 3065058 | c.1134C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065085 | c.1105_1107delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065097 | c.1095C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065106 | c.1086C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065109 | c.1081_1083delAGAinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065126 | p.Ser356Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065130 | c.1062A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065139 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065154 | c.1038G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067619 | c.327A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067622 | c.324C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067631 | c.315C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067640 | c.306G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067680 | p.Cys89Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067685 | c.261A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067688 | c.258G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067694 | c.252G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067698 | p.Thr83Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067709 | c.237G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067715 | c.229_231delAGCinsTCG | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067721 | c.225T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067724 | c.222G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067742 | c.204A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067760 | c.186G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3625216 | c.-306G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625231 | c.-321G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625243 | c.-333T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625246 | c.-336G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625252 | c.1362G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625255 | c.-345T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625258 | c.-348G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625285 | c.-375G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625291 | c.-381A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625312 | c.-402G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625315 | c.-405G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625325 | p.His430Arg | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625333 | c.-423C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625711 | c.903C>T | synonymous_variant | 0.89 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.89 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 0.89 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.89 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625741 | c.-831G>A | upstream_gene_variant | 0.85 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 0.85 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625753 | p.Ala287Gln | missense_variant | 0.84 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.82 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 0.82 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625770 | c.-860C>T | upstream_gene_variant | 0.82 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 0.75 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627059 | c.-446G>C | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627062 | c.-449G>A | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 0.9 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| rpoA | 3877647 | c.861C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877671 | c.837C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | c.831G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877683 | c.825G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877695 | c.813C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877728 | c.780C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877731 | c.777G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877734 | c.774G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877749 | c.759C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877785 | c.723C>A | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3877803 | c.705G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877856 | c.652T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877875 | c.633T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877887 | c.621G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877893 | c.615C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877923 | c.585C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877962 | c.546G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877995 | c.513G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878019 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878034 | c.474A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878046 | c.462T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878050 | p.Arg153Lys | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878079 | c.429C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878145 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878175 | c.333G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878197 | p.Glu104Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.82 | pyrazinamide | |
| clpC1 | 4038310 | p.Val799Leu | missense_variant | 0.82 | pyrazinamide | |
| clpC1 | 4038320 | c.2385G>C | synonymous_variant | 0.85 | pyrazinamide | |
| clpC1 | 4038325 | p.Val794Leu | missense_variant | 0.85 | pyrazinamide | |
| clpC1 | 4038329 | c.2376G>A | synonymous_variant | 0.85 | pyrazinamide | |
| clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038401 | c.2302_2304delTTGinsCC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038410 | c.2295C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038461 | c.2244G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038474 | p.Ser744Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038488 | p.Ala739Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038519 | p.Arg729Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038533 | p.Arg724Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038536 | c.2169C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038551 | c.2154C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038563 | c.2142C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038584 | c.2121G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038587 | c.2118C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038721 | c.1984C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038725 | c.1980C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038767 | c.1938G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038779 | c.1926C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038842 | c.1863G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038905 | c.1800A>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038980 | c.1725C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039021 | c.1684C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039031 | c.1674T>A | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039067 | c.1638G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039070 | c.1635G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039073 | c.1632C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039079 | c.1626C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039091 | c.1614G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039124 | c.1581C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039187 | c.1518G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039241 | c.1464G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039250 | c.1455C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039280 | c.1425G>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039283 | c.1422C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039310 | c.1395A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039313 | c.1392C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039320 | p.Ala462Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039346 | c.1359G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039361 | c.1344C>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039394 | c.1311G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.98 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039454 | c.1251A>T | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039472 | c.1233G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.98 | pyrazinamide | Uncertain significance |
| clpC1 | 4039574 | p.Ala377Gly | missense_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039592 | c.1113G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039649 | c.1056G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039652 | c.1053G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039670 | c.1035G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039685 | c.1020C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039763 | c.942C>T | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039814 | c.891C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>T | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039829 | c.874_876delTTGinsCC | frameshift_variant&missense_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039832 | c.873C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039913 | c.792C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039925 | c.780C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039943 | c.762G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039964 | c.741C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040087 | c.618G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040126 | c.579C>T | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.82 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.82 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.82 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.82 | pyrazinamide | |
| clpC1 | 4040303 | c.402G>C | synonymous_variant | 0.83 | pyrazinamide | |
| clpC1 | 4040411 | c.294T>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040433 | c.271_272delAGinsTC | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040441 | c.264C>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040444 | c.261C>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040456 | c.249C>T | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040462 | c.243C>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040468 | c.237G>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040495 | c.210C>A | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>A | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040600 | c.105A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040618 | c.87C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.93 | pyrazinamide | |
| glpK | 4138511 | c.1245C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138514 | c.1242A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138526 | p.Asp410Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138529 | c.1227G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138535 | c.1221T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138562 | c.1194G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138565 | c.1191G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138583 | c.1173G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138598 | c.1158G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138607 | c.1149G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138616 | p.Ala380Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138622 | c.1134C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138628 | c.1128T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138634 | c.1122G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138661 | c.1095T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138670 | c.1086G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138696 | p.Pro354Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138697 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138703 | c.1051_1053delCGCinsAG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138727 | c.1029C>G | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138730 | c.1026C>T | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138784 | c.972G>T | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138787 | c.969C>T | synonymous_variant | 0.96 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138796 | c.960A>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138802 | c.954G>C | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138808 | c.948G>T | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138811 | c.945C>G | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240779 | p.His306Arg | missense_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240828 | c.966G>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240837 | c.975C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240858 | c.996G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247511 | p.Tyr333Phe | missense_variant | 0.92 | ethambutol | |
| embB | 4248007 | c.1494C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248011 | p.Ser500Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248020 | c.1507T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248028 | c.1515C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4248041 | p.Ala510Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248044 | p.Lys511Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248052 | c.1539G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248061 | c.1548G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248063 | p.Ala517Glu | missense_variant | 1.0 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248106 | c.1593C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248118 | c.1605T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248133 | c.1620C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630_1632delTTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248158 | p.Cys549Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248167 | p.Thr552Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248170 | p.Ala553Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248173 | p.Val554Leu | missense_variant | 1.0 | ethambutol | |
| embB | 4248199 | c.1686A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | c.1693_1695delAGCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248225 | p.Ala571Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248242 | p.Val577Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4248252 | p.Gly580Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248264 | p.Phe584Cys | missense_variant | 1.0 | ethambutol | |
| embB | 4248277 | c.1764G>C | synonymous_variant | 1.0 | ethambutol | |
| ubiA | 4269149 | p.Val229Met | missense_variant | 0.9 | ethambutol | |
| aftB | 4269156 | c.-320C>G | upstream_gene_variant | 0.9 | ethambutol | |
| aftB | 4269177 | c.-341G>T | upstream_gene_variant | 0.9 | ethambutol | |
| aftB | 4269183 | c.-347T>C | upstream_gene_variant | 0.9 | ethambutol | |
| ubiA | 4269187 | p.Thr216Ser | missense_variant | 0.9 | ethambutol | Uncertain significance |
| aftB | 4269198 | c.-362C>T | upstream_gene_variant | 0.9 | ethambutol | |
| aftB | 4269201 | c.-365A>G | upstream_gene_variant | 0.9 | ethambutol | |
| ubiA | 4269220 | p.Ala205Lys | missense_variant | 0.9 | ethambutol | |
| ubiA | 4269222 | c.612T>C | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
| aftB | 4269228 | c.-392C>G | upstream_gene_variant | 0.9 | ethambutol | |
| aftB | 4269234 | c.-398A>G | upstream_gene_variant | 0.9 | ethambutol | |
| ubiA | 4269243 | p.His197Gln | missense_variant | 0.9 | ethambutol | |
| aftB | 4269249 | c.-413G>A | upstream_gene_variant | 0.9 | ethambutol | |
| ubiA | 4269256 | p.Tyr193Phe | missense_variant | 0.9 | ethambutol | |
| aftB | 4269258 | c.-422C>G | upstream_gene_variant | 0.9 | ethambutol |
