TB-Profiler result

Run: ERR5311091

Summary

Run ID: ERR5311091

Sample name:

Date: 2024-03-26T20:50:37.825711

Number of reads: 792936

Percentage reads mapped: 33.55

Median coverage: 24.0

Strain: La3;lineage4.2;lineage4.6.4;lineage4.9;lineage6.3

Spoligotype:

Drug-resistance: Other


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.3 West-Africa 2 RD702 0.06
lineage4.2 Euro-American None 0.14
lineage4.6.4 Euro-American None 0.12
lineage6.1.3 West-Africa 2 RD702 0.1
lineage4 Euro-American None 0.52
lineage1.1.1 Indo-Oceanic RD239 0.05
lineage4.9 Euro-American (H37Rv-like) None 0.83
La3 M.orygis None 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Tyr384Asn Mutation from literature
p.Thr437Ala Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide ethA c.193_195delCGAinsAG Assoc w R
clofazimine pepQ c.1056_1057insCA Assoc w R - Interim
c.1047_1048delGA Assoc w R - Interim
c.1033_1035delGCTinsCC Assoc w R - Interim
c.865_867delCACinsAT Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.196_198delAACinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.205_207delCTGinsTT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.421_423delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.562_564delTTGinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2065_2067delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.391_393delACCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.190_192delCTCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.1056_1057insCA Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.1047_1048delGA Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.1033_1035delGCTinsCC Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.865_867delCACinsAT Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490978 c.196_198delAACinsCA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490987 c.205_207delCTGinsTT frameshift_variant&synonymous_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491203 c.421_423delCAGinsGA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303492 c.562_564delTTGinsCT frameshift_variant&synonymous_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsAG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304995 c.2065_2067delTTGinsCA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pepQ 2859362 c.1056_1057insCA frameshift_variant 1.0 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
pepQ 2859370 c.1047_1048delGA frameshift_variant 1.0 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
pepQ 2859384 c.1033_1035delGCTinsCC frameshift_variant&synonymous_variant 1.0 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
pepQ 2859552 c.865_867delCACinsAT frameshift_variant&synonymous_variant 1.0 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
fbiB 3641925 c.391_393delACCinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987033 c.190_192delCTCinsTG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247663 p.Tyr384Asn missense_variant 1.0 ethambutol Mutation from literature
embB 4247822 p.Thr437Ala missense_variant 1.0 ethambutol Mutation from literature
ethA 4327279 c.193_195delCGAinsAG frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 1.0 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>C synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 1.0 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 888 c.888C>G synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 930 c.930G>A synonymous_variant 1.0 isoniazid
dnaA 939 c.939C>G synonymous_variant 1.0 isoniazid
dnaA 945 c.945G>A synonymous_variant 1.0 isoniazid
dnaA 955 c.955_957delAGAinsCG frameshift_variant&synonymous_variant 1.0 isoniazid Uncertain significance
dnaA 963 c.963C>G synonymous_variant 1.0 isoniazid
dnaA 966 c.966T>C synonymous_variant 1.0 isoniazid
dnaA 969 c.969G>A synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>C synonymous_variant 1.0 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 987 c.987C>T synonymous_variant 1.0 isoniazid
dnaA 990 c.990A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 1.0 isoniazid
dnaA 1003 c.1003C>T synonymous_variant 1.0 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 1.0 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 1.0 isoniazid
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>A synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1206 c.1206G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 1.0 isoniazid
dnaA 1269 c.1269C>T synonymous_variant 1.0 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 1.0 isoniazid
dnaA 1315 c.1315_1317delGCAinsTG frameshift_variant&stop_gained 1.0 isoniazid Uncertain significance
dnaA 1329 c.1329A>C synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 1.0 isoniazid
dnaA 1350 c.1350G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1359 c.1359G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1374 c.1374G>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1395 c.1395G>A synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 1.0 isoniazid
gyrB 5284 c.45G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5293 c.54C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5302 c.63A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5305 c.66G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5308 c.69G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5326 c.87T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5362 c.123T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5404 c.165C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5410 c.171G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5812 c.573C>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 5926 c.687G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6046 c.807C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6049 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6079 c.840C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6139 c.900G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6196 c.957C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6217 c.978G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6322 c.-980G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6343 c.-959G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6352 c.-950C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6787 c.-515G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6820 c.-482C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6931 c.-371A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6941 c.-361C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6961 c.-341G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6964 c.1725C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6965 c.-337_-335delAGTinsTCC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6991 c.-311C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7151 c.1912C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7207 c.-95C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7219 c.-83C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7258 c.-44G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7430 c.129G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7460 c.159C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7463 c.162G>A synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7556 c.255C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7778 c.477G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7941 p.Glu214Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7970 c.669T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7973 c.672A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7976 c.675C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7988 c.687G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8020 p.Thr240Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8030 c.729C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8042 c.741C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8048 c.747C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8051 c.750C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8054 c.753T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8102 c.801C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsGG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8306 c.1005C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8310 c.1009C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8573 c.1272G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8628 c.1327C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8882 c.1581G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8912 c.1611G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9002 c.1701C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9003 c.1702C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9065 c.1764C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9077 c.1776C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9146 c.1845C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9149 c.1848C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 c.1951_1953delGTCinsAT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9266 c.1965C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9455 c.2154T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9476 c.2175G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9548 c.2247T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9551 c.2250G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9572 c.2271C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9641 c.2340C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 490863 c.81C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490945 c.163C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490977 c.195C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491010 c.228C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491034 c.252C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491208 c.426G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491223 c.441C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491229 c.447C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491262 c.480C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491316 c.534C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491355 c.573C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491370 c.588C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491652 c.870C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491688 c.906A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491697 c.915G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575506 c.159C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575512 c.165A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575545 c.198C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575548 c.201C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575572 c.225T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575633 c.286_288delGCAinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575652 p.Arg102Gln missense_variant 1.0 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575671 c.324G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575686 c.339G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575732 c.385_387delCTTinsTG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575737 c.390T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575851 c.504C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575878 c.531A>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575892 p.Ala182Val missense_variant 1.0 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575946 p.Thr200Met missense_variant 1.0 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575956 c.609G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575965 c.618C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576385 c.1038T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576400 c.1053C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 576403 c.1056C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576415 c.1068C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576421 c.1074T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576424 c.1077T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576425 c.1078_1080delGTGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576430 c.1083G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 576433 c.1086C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576436 c.1089A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576439 c.1092G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576445 c.1098C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 576448 c.1101A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576460 c.1113C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576469 c.1122G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576472 c.1125C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576481 c.1134C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576510 p.Thr388Ile missense_variant 1.0 ethionamide
isoniazid
mshA 576517 c.1170G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 576518 p.Ser391Ala missense_variant 1.0 ethionamide
isoniazid
ccsA 619654 c.-237A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619681 c.-210G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619708 c.-183G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619713 c.-178_-177delCGinsTC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619720 c.-171C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619727 c.-164A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619729 c.-162delGinsCGCCGAT upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619733 c.-158_-156delGCGinsCC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619744 c.-147A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619766 c.-125_-123delACGinsGA upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619771 c.-120C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619786 c.-105G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620214 c.324C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620238 c.348G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620280 c.390C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620290 p.Tyr134Asn missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620314 c.424C>T synonymous_variant 1.0 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620317 p.Val143Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620325 c.435G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620404 c.514C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620457 c.567C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620685 c.795G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620709 c.819G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620760 c.870C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620780 p.Val297Ala missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
Rv0565c 656922 c.547_549delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656936 p.Thr179Ala missense_variant 1.0 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 1.0 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 1.0 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 1.0 ethionamide
Rv0565c 656964 c.507C>G synonymous_variant 1.0 ethionamide
Rv0565c 656967 c.504T>C synonymous_variant 1.0 ethionamide
Rv0565c 656973 c.498A>G synonymous_variant 1.0 ethionamide
Rv0565c 656976 c.493_495delGCGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656990 p.Lys161Gln missense_variant 1.0 ethionamide
Rv0565c 656991 c.480G>A synonymous_variant 1.0 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657006 p.Asp155Glu missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657267 c.202_204delTCGinsAGC synonymous_variant 1.0 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657587 c.-117C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657590 c.-120G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657623 c.-153C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsAT upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.97 ethionamide
Rv0565c 657728 c.-258C>T upstream_gene_variant 0.97 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.97 ethionamide
hadA 731687 c.-243G>C upstream_gene_variant 1.0 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 1.0 isoniazid
hadA 731693 c.-237_-236insGTTTGACACCAGAT upstream_gene_variant 1.0 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 1.0 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 1.0 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731738 c.-192G>C upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 1.0 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 1.0 isoniazid
hadA 731837 c.-93C>T upstream_gene_variant 1.0 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 732223 c.294G>T synonymous_variant 1.0 isoniazid
hadA 732226 c.297G>C synonymous_variant 1.0 isoniazid
hadA 732229 c.300C>T synonymous_variant 1.0 isoniazid
hadA 732238 c.309G>C synonymous_variant 1.0 isoniazid
hadA 732250 c.321C>G synonymous_variant 1.0 isoniazid
hadA 732263 p.Val112Met missense_variant 1.0 isoniazid
hadA 732295 c.366G>C synonymous_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732317 c.388_390delGAGinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732322 p.Glu131Asp missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Ile missense_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732355 c.426G>C synonymous_variant 1.0 isoniazid
hadA 732361 c.432C>G synonymous_variant 1.0 isoniazid
hadA 732378 c.449_450insGGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732391 c.462T>A synonymous_variant 1.0 isoniazid
nusG 734331 c.78G>A synonymous_variant 1.0 rifampicin
nusG 734337 c.84G>C synonymous_variant 1.0 rifampicin
nusG 734352 c.99T>C synonymous_variant 1.0 rifampicin
nusG 734361 c.108C>T synonymous_variant 1.0 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734376 c.123G>A synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>A synonymous_variant 1.0 rifampicin
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734616 c.363C>A synonymous_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734631 c.378G>A synonymous_variant 1.0 rifampicin
nusG 734634 c.381G>C synonymous_variant 1.0 rifampicin
nusG 734640 c.387C>A synonymous_variant 1.0 rifampicin
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734652 c.399T>C synonymous_variant 1.0 rifampicin
nusG 734661 c.408A>C synonymous_variant 1.0 rifampicin
nusG 734664 c.411T>G synonymous_variant 1.0 rifampicin
nusG 734670 c.417G>A synonymous_variant 1.0 rifampicin
nusG 734673 c.420A>G synonymous_variant 1.0 rifampicin
nusG 734680 p.Ala143Ser missense_variant 1.0 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734712 c.459G>C synonymous_variant 1.0 rifampicin
nusG 734718 c.465G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 1.0 rifampicin
nusG 734722 p.Thr157Ala missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734733 c.480T>G synonymous_variant 1.0 rifampicin
nusG 734736 c.483C>G synonymous_variant 1.0 rifampicin
nusG 734742 c.489T>G synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>C synonymous_variant 1.0 rifampicin
nusG 734762 p.Ala170Val missense_variant 1.0 rifampicin
nusG 734769 c.516G>A synonymous_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734793 c.540C>T synonymous_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 1.0 rifampicin
nusG 734880 c.627C>T synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734904 c.651G>A synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 1.0 rifampicin
rpoB 759635 c.-172C>T upstream_gene_variant 1.0 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 1.0 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759661 c.-146G>C upstream_gene_variant 1.0 rifampicin
rpoB 759670 c.-137C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 1.0 rifampicin
rpoB 759676 c.-131A>G upstream_gene_variant 1.0 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>T synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760124 c.318C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760178 c.372G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 1.0 rifampicin
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760211 c.405C>T synonymous_variant 1.0 rifampicin
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760304 c.498G>A synonymous_variant 1.0 rifampicin
rpoB 760307 c.501T>G synonymous_variant 1.0 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760409 c.603C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 1.0 rifampicin
rpoB 760415 c.609C>G synonymous_variant 1.0 rifampicin
rpoB 760418 c.612G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760427 c.621G>A synonymous_variant 1.0 rifampicin
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>G synonymous_variant 1.0 rifampicin
rpoB 760497 c.691C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760528 p.Gln241Arg missense_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760577 c.771G>A synonymous_variant 1.0 rifampicin
rpoB 760580 c.774G>A synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760604 c.798G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760610 c.804G>A synonymous_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760658 c.852G>A synonymous_variant 1.0 rifampicin
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761030 c.1224G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>A synonymous_variant 1.0 rifampicin
rpoB 761066 c.1260G>C synonymous_variant 1.0 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761175 c.1369C>T synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761201 c.1395G>A synonymous_variant 1.0 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 1.0 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761210 c.1404C>T synonymous_variant 1.0 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 1.0 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761439 c.1633_1635delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761459 c.1653G>C synonymous_variant 1.0 rifampicin
rpoB 761462 c.1656C>G synonymous_variant 1.0 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 1.0 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 1.0 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 1.0 rifampicin
rpoB 761528 c.1722C>T synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>A synonymous_variant 1.0 rifampicin
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>A synonymous_variant 1.0 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761651 c.1845C>T synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 1.0 rifampicin
rpoB 761721 c.1917delA frameshift_variant 1.0 rifampicin
rpoB 761727 p.Ser641Val missense_variant 1.0 rifampicin
rpoB 761732 c.1926delCinsGG frameshift_variant&synonymous_variant 1.0 rifampicin
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761822 c.2016C>T synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>G synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>G synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>A synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>A synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563_2565delTTGinsCT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 1.0 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762449 c.-921C>G upstream_gene_variant 1.0 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762482 c.-888C>A upstream_gene_variant 1.0 rifampicin
rpoB 762485 c.2679G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 1.0 rifampicin
rpoB 762489 p.Val895Gln missense_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762518 c.-852C>G upstream_gene_variant 1.0 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoB 762537 c.2731_2733delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 c.3007_3009delATGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 1.0 rifampicin
rpoC 762836 c.-534C>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762890 c.-480C>T upstream_gene_variant 1.0 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 1.0 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763179 c.-191C>T upstream_gene_variant 1.0 rifampicin
rpoB 763193 c.3387C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763435 c.66A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763501 c.132C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 1.0 rifampicin
rpoC 763639 c.270G>A synonymous_variant 1.0 rifampicin
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.96 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>A synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763789 c.420C>T synonymous_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763819 c.450G>C synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763867 c.498C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763882 c.513G>A synonymous_variant 1.0 rifampicin
rpoC 763885 c.516C>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763904 p.Ala179Thr missense_variant 1.0 rifampicin
rpoC 763916 p.Glu183Gln missense_variant 1.0 rifampicin
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764062 c.693C>A synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764110 c.741C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764119 c.750G>A synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764224 c.855G>A synonymous_variant 1.0 rifampicin
rpoC 764230 c.861G>A synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764266 c.897T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764272 c.903G>T synonymous_variant 0.97 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 1.0 rifampicin
rpoC 764308 c.939G>C synonymous_variant 1.0 rifampicin
rpoC 764311 c.942C>G synonymous_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764374 c.1005C>T synonymous_variant 1.0 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764398 c.1029G>C synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764648 c.1279C>A synonymous_variant 1.0 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 1.0 rifampicin
rpoC 764656 c.1287C>G synonymous_variant 1.0 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764681 c.1312C>T synonymous_variant 1.0 rifampicin
rpoC 764714 c.1345C>T synonymous_variant 1.0 rifampicin
rpoC 764720 c.1351C>T synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764869 c.1500C>G synonymous_variant 1.0 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764918 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764938 c.1569G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765022 c.1653G>C synonymous_variant 1.0 rifampicin
rpoC 765034 c.1665T>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>A synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>T synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765122 c.1753C>T synonymous_variant 1.0 rifampicin
rpoC 765131 c.1762C>T synonymous_variant 1.0 rifampicin
rpoC 765146 p.Pro593Asp missense_variant 1.0 rifampicin
rpoC 765151 c.1782G>C synonymous_variant 1.0 rifampicin
rpoC 765311 p.Ala648Ser missense_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>G synonymous_variant 1.0 rifampicin
rpoC 765326 p.His653Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765340 p.Gln657His missense_variant 1.0 rifampicin
rpoC 765349 p.Asp660Glu missense_variant 1.0 rifampicin
rpoC 765350 c.1981_1983delGCGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765358 p.Met663Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765405 p.Leu679Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765445 c.2076G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765526 c.2157C>A synonymous_variant 1.0 rifampicin
rpoC 765529 c.2160C>G synonymous_variant 1.0 rifampicin
rpoC 765535 c.2166C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>A synonymous_variant 1.0 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 1.0 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 1.0 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 1.0 rifampicin
rpoC 765612 p.His748Arg missense_variant 1.0 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765676 c.2307G>A synonymous_variant 1.0 rifampicin
rpoC 765688 c.2319G>C synonymous_variant 1.0 rifampicin
rpoC 765689 c.2320C>T synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 1.0 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 1.0 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765760 c.2391C>T synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>G synonymous_variant 1.0 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766018 c.2649C>T synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 0.96 rifampicin
rpoC 766063 c.2694C>G synonymous_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766093 c.2724C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766094 p.Thr909Ala missense_variant 1.0 rifampicin
rpoC 766114 c.2745C>T synonymous_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 1.0 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766306 c.2937C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766351 c.2982C>G synonymous_variant 1.0 rifampicin
rpoC 766357 c.2988C>T synonymous_variant 0.97 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 1.0 rifampicin
rpoC 766375 c.3006C>G synonymous_variant 1.0 rifampicin
rpoC 766378 c.3009C>T synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766397 c.3028C>T synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>A synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 1.0 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 1.0 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 1.0 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766915 c.3546C>T synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767032 c.3663G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767035 c.3666G>T synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>G synonymous_variant 1.0 rifampicin
rpoC 767086 c.3717C>T synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767170 c.3801C>T synonymous_variant 1.0 rifampicin
rpoC 767203 c.3834C>G synonymous_variant 1.0 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>G synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767288 c.3919C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781667 c.108C>G synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>A synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>T synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781847 c.288G>A synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>A synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800225 c.-584T>C upstream_gene_variant 1.0 linezolid
rplC 800232 c.-577G>A upstream_gene_variant 1.0 linezolid
rplC 800237 c.-572T>C upstream_gene_variant 1.0 linezolid
rplC 800244 c.-565A>G upstream_gene_variant 1.0 linezolid
rplC 800267 c.-542T>C upstream_gene_variant 1.0 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 1.0 linezolid
rplC 800278 c.-531A>G upstream_gene_variant 1.0 linezolid
rplC 800285 c.-524_-523insC upstream_gene_variant 1.0 linezolid
rplC 800293 c.-516_-515insGC upstream_gene_variant 1.0 linezolid
rplC 800297 c.-511_-498delTGAAATTGATCGCG upstream_gene_variant 1.0 linezolid
rplC 800321 c.-488T>C upstream_gene_variant 1.0 linezolid
rplC 800341 c.-468G>C upstream_gene_variant 1.0 linezolid
rplC 800349 c.-460delCinsGT upstream_gene_variant 1.0 linezolid
rplC 800358 c.-450delT upstream_gene_variant 1.0 linezolid
rplC 800386 c.-423T>C upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 0.94 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.96 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.96 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.97 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.97 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.97 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 0.97 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.97 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.97 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.97 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.96 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.97 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.97 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.97 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.97 linezolid
rplC 800726 c.-83G>C upstream_gene_variant 0.97 linezolid
rplC 800729 c.-80G>T upstream_gene_variant 0.97 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.97 linezolid
rplC 800744 c.-65G>A upstream_gene_variant 0.97 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.97 linezolid
rplC 800796 c.-13A>T upstream_gene_variant 1.0 linezolid
rplC 800797 c.-12T>C upstream_gene_variant 1.0 linezolid
rplC 800799 c.-9_-8delGA upstream_gene_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800889 c.81C>A synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800901 c.93C>G synonymous_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 0.94 linezolid
rplC 800907 c.99C>G synonymous_variant 0.97 linezolid
rplC 800913 c.105G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800919 c.111C>G synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800976 c.168G>A synonymous_variant 1.0 linezolid
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>C synonymous_variant 1.0 linezolid
rplC 800996 p.Asn63Thr missense_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801216 c.408C>A synonymous_variant 1.0 linezolid
rplC 801219 c.411C>T synonymous_variant 1.0 linezolid
rplC 801220 p.Ser138Ala missense_variant 1.0 linezolid
rplC 801246 c.438C>G synonymous_variant 1.0 linezolid
rplC 801252 c.444G>C synonymous_variant 1.0 linezolid
rplC 801267 c.459A>T synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801333 c.525G>A synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801372 c.564G>A synonymous_variant 1.0 linezolid
rplC 801375 c.567C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801417 c.609T>C synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
rplC 801456 c.648G>A synonymous_variant 1.0 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 1.0 linezolid
fbiC 1303441 c.511T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303458 c.528G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303467 c.537C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303479 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303653 c.723G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303654 c.724C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303713 c.783C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303758 c.828G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303768 p.Ser280Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303842 c.912C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303866 p.Glu312Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303874 p.Leu315Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303887 c.957G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303902 c.972G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304120 p.Lys397Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304124 c.1194C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304511 c.1581C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304515 p.Ala529Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304679 c.1749G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304706 c.1776C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304712 c.1782C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304736 c.1806G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304904 c.1974G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305001 p.Ile691Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305014 p.Thr695Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305027 c.2097G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305036 c.2106G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305051 c.2121G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305088 p.Val720Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305144 c.2214G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305165 c.2235G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305192 c.2262C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305219 p.His763Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364661 c.249C>G synonymous_variant 1.0 pyrazinamide
sigE 1364671 c.259C>T synonymous_variant 1.0 pyrazinamide
sigE 1364676 c.264C>A synonymous_variant 1.0 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364751 c.339C>G synonymous_variant 1.0 pyrazinamide
sigE 1364754 c.342G>A synonymous_variant 1.0 pyrazinamide
sigE 1364757 c.345G>A synonymous_variant 1.0 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364772 c.360G>T synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>G synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364866 c.454_456delGCTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 1.0 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 1.0 pyrazinamide
sigE 1364955 c.543G>T synonymous_variant 1.0 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 1.0 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364967 c.555C>T synonymous_variant 1.0 pyrazinamide
sigE 1364968 c.556_558delCTGinsTA frameshift_variant&stop_gained 0.92 pyrazinamide Uncertain significance
sigE 1364980 c.568_570delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
atpE 1461107 c.63C>G synonymous_variant 1.0 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461161 c.117C>T synonymous_variant 1.0 bedaquiline
atpE 1461164 c.120C>T synonymous_variant 1.0 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>A synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 1.0 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>T synonymous_variant 1.0 bedaquiline
atpE 1461245 c.201C>T synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
atpE 1461260 c.216G>A synonymous_variant 1.0 bedaquiline
atpE 1461261 c.217C>T synonymous_variant 1.0 bedaquiline
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
fabG1 1672337 c.-1102_27del conservative_inframe_deletion 1.0 ethionamide
isoniazid
inhA 1673487 c.-715T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673499 c.-703T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673505 c.-697A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673520 c.-682C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673523 c.-679G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673538 c.-664G>A upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673568 c.-634C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673571 c.-631C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673658 c.-544G>A upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673685 c.-517C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673697 c.-505G>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsGG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1673721 c.-481C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1673736 c.-466G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
inhA 1673766 c.-436C>T upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1673767 p.Asn110Asp missense_variant 1.0 ethionamide
isoniazid
fabG1 1673797 p.Ala120Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673809 c.370_372delTCGinsGT frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1673826 c.-376C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1673832 c.-370A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673842 p.Met135Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673849 p.Phe137Tyr missense_variant 1.0 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673859 c.-343G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673871 c.-331C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673892 c.-310C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673916 c.-286A>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673946 c.-256C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673982 c.-220G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673991 c.-211C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674015 c.-187C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674018 c.-184G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674037 p.Gln200Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674045 c.-157G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674096 c.-106G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674117 c.-85C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674133 p.Ile232Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674273 c.72C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674279 c.78A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674285 c.84A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674303 c.102C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674315 c.114C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674321 c.120G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674328 c.127C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674331 c.130C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674337 c.136C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674348 c.147C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674361 c.160C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674367 p.Ala56Gln missense_variant 1.0 ethionamide
isoniazid
inhA 1674375 c.174C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674384 c.183C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674477 c.276G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674501 c.300G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674513 c.312C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674558 c.357C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674594 c.393C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674609 c.408G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674620 p.Pro140His missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674702 c.501G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674762 c.561T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674799 p.Ser200Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674804 c.603G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674840 c.639C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674882 c.681G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674927 c.726G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674945 p.Asp248Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674954 c.753G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674977 p.Tyr259Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1675002 c.801A>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833593 c.52_54delTCTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833727 c.186G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833754 c.213G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833799 c.258C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833805 c.264C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833806 c.265C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833817 c.276C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833904 p.Glu121Asp missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833916 c.375C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833919 c.378C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833937 c.396G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833961 c.420C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834033 c.492C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834045 c.504G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0