TB-Profiler result

Run: SRR23961558

Summary

Run ID: SRR23961558

Sample name:

Date: 2024-03-24T15:17:49.105090

Number of reads: 3496070

Percentage reads mapped: 54.01

Median coverage: 27.0

Strain: lineage2.1;lineage4.9;lineage6.3

Spoligotype:

Drug-resistance: RR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.1.2 Indo-Oceanic RD239 0.11
lineage6.3 West-Africa 2 RD702 0.19
La1.2.BCG M.bovis None 0.26
lineage4 Euro-American None 0.62
lineage2.1 East-Asian (non-Beijing) None 0.23
lineage4.9 Euro-American (H37Rv-like) None 0.87
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.196_198delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.205_207delCTGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.295_297delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.409_411delGGGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.604_606delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.772_774delACGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490978 c.196_198delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490987 c.205_207delCTGinsGC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491077 c.295_297delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491191 c.409_411delGGGinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303534 c.604_606delTCGinsGC frameshift_variant&missense_variant 0.99 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
fbiA 3641314 c.772_774delACGinsGC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 22 c.22_24delGGCinsAT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 33 c.33A>C synonymous_variant 1.0 isoniazid
dnaA 51 c.51C>G synonymous_variant 1.0 isoniazid
dnaA 594 c.594C>G synonymous_variant 1.0 isoniazid
dnaA 600 c.600T>C synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 633 c.633T>G synonymous_variant 1.0 isoniazid
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>T synonymous_variant 1.0 isoniazid
dnaA 651 c.651G>A synonymous_variant 1.0 isoniazid
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 660 c.660G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>T synonymous_variant 1.0 isoniazid
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>A synonymous_variant 1.0 isoniazid
dnaA 682 c.682T>C synonymous_variant 1.0 isoniazid
dnaA 693 c.693A>C synonymous_variant 1.0 isoniazid
dnaA 699 c.699G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 1.0 isoniazid
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 765 c.765G>A synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>T synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 864 c.864C>T synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>G synonymous_variant 1.0 isoniazid
dnaA 912 c.912T>G synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1179 c.1179G>C synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>A synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1206 c.1206G>T synonymous_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>A synonymous_variant 1.0 isoniazid
dnaA 1314 c.1314A>C synonymous_variant 1.0 isoniazid
dnaA 1320 c.1320G>C synonymous_variant 1.0 isoniazid
dnaA 1323 c.1323C>G synonymous_variant 1.0 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 1.0 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1368 c.1368T>C synonymous_variant 1.0 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1375 c.1375_1377delTTGinsCA frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1383 c.1383A>G synonymous_variant 0.97 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.97 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.97 isoniazid
dnaA 1401 c.1401C>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1404 c.1404T>C synonymous_variant 0.96 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.96 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.96 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.96 isoniazid
dnaA 1425 c.1425C>T synonymous_variant 0.96 isoniazid
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6142 c.903G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6259 p.Asp340Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6266 p.Pro343Ala missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6274 c.1035C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6334 c.-968G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6721 c.1482C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6724 c.-578G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6766 c.-536G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6965 c.-337_-335delAGTinsTCC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7028 p.Ala597Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7051 c.1812A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7072 c.-230G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7093 c.-209T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7096 c.-206G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7781 c.480G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 0.93 levofloxacin
moxifloxacin
gyrA 7805 c.504C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7832 c.531G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7874 c.573G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7880 c.579C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 7901 c.600G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7937 c.636A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7942 p.Glu214Ala missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7958 c.657C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8639 c.1338G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8690 c.1389C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8706 c.1405C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8735 c.1434C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8819 c.1518C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8894 c.1593C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8936 c.1635G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8982 p.Cys561Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9146 c.1845C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9147 c.1846_1848delGGCinsAT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9152 c.1851C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491010 c.228C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491070 c.288G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491076 c.294G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491175 c.393G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491178 c.396G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491265 c.483G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491328 c.546C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491393 p.Thr204Lys missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491397 p.Glu205Asp missense_variant 0.97 clofazimine
pretomanid
delamanid
mshA 574619 c.-729C>G upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574643 c.-705C>A upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574671 c.-677_-675delGCAinsCTG upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574683 c.-665_-663delTCGinsCC upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574688 c.-660G>C upstream_gene_variant 0.93 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574712 c.-636A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574742 c.-606G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574763 c.-585T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574766 c.-582T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574782 c.-566C>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575545 c.198C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.97 ethionamide
isoniazid
mshA 575566 c.219G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.97 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575587 c.240C>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575590 c.243T>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575644 c.297G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575649 p.Val101Ala missense_variant 0.99 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.99 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575692 c.345G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.99 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.99 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.99 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.99 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575809 c.462C>T synonymous_variant 0.99 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575824 c.477T>A synonymous_variant 0.99 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 0.99 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 0.99 ethionamide
isoniazid
mshA 575938 c.591G>A synonymous_variant 0.99 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575947 c.600G>A synonymous_variant 0.99 ethionamide
isoniazid Not assoc w R - Interim
mshA 575948 p.Val201Ile missense_variant 0.99 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.99 ethionamide
isoniazid Not assoc w R - Interim
mshA 575980 c.633T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 0.98 ethionamide
isoniazid
mshA 576004 c.657T>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 576017 p.Val224Leu missense_variant 0.94 ethionamide
isoniazid
ccsA 619503 c.-388A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619513 c.-378G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619520 c.-371C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619549 c.-342C>T upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620166 c.276G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620169 c.279G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620204 p.Val105Ala missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620268 c.378G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Phe missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620400 c.510C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620406 c.516G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620427 c.537C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620449 p.Leu187Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620475 c.585G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620688 c.798G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656889 c.582A>G synonymous_variant 0.91 ethionamide
Rv0565c 656943 c.528G>C synonymous_variant 0.97 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.97 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 0.96 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 0.96 ethionamide
Rv0565c 656967 c.504T>C synonymous_variant 0.96 ethionamide
Rv0565c 656973 c.498A>C synonymous_variant 0.96 ethionamide
Rv0565c 656976 p.Ala165Val missense_variant 0.96 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 0.96 ethionamide
Rv0565c 656989 p.Lys161Thr missense_variant 0.96 ethionamide
Rv0565c 656991 c.480G>A synonymous_variant 0.96 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 0.96 ethionamide
Rv0565c 657018 c.453C>A synonymous_variant 1.0 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657039 c.432C>T synonymous_variant 1.0 ethionamide
Rv0565c 657056 p.Val139Leu missense_variant 1.0 ethionamide
Rv0565c 657060 c.411G>A synonymous_variant 1.0 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.92 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 0.93 ethionamide
Rv0565c 657602 c.-134_-132delGCCinsTG upstream_gene_variant 0.93 ethionamide
Rv0565c 657608 c.-138C>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657626 c.-156C>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657668 c.-198C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657724 c.-254A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
hadA 731686 c.-244_-243insAT upstream_gene_variant 1.0 isoniazid
hadA 731689 c.-241_-240insCTTTTGAG upstream_gene_variant 1.0 isoniazid
hadA 731693 c.-237C>T upstream_gene_variant 1.0 isoniazid
hadA 731694 c.-235_-234delCG upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 1.0 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 1.0 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 1.0 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 1.0 isoniazid
hadA 731817 c.-113C>A upstream_gene_variant 1.0 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 731864 c.-66C>T upstream_gene_variant 1.0 isoniazid
hadA 732241 c.312C>T synonymous_variant 1.0 isoniazid
hadA 732250 c.321C>T synonymous_variant 1.0 isoniazid
hadA 732253 c.324T>C synonymous_variant 1.0 isoniazid
hadA 732259 c.330T>C synonymous_variant 1.0 isoniazid
hadA 732260 p.Ser111Ala missense_variant 1.0 isoniazid Uncertain significance
hadA 732268 c.339T>G synonymous_variant 1.0 isoniazid
hadA 732270 p.Glu114Val missense_variant 1.0 isoniazid
hadA 732272 p.Ala115Ser missense_variant 1.0 isoniazid
hadA 732319 c.390G>A synonymous_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Val missense_variant 1.0 isoniazid Uncertain significance
hadA 732334 c.405G>T synonymous_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732370 c.441C>T synonymous_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734102 c.-152G>C upstream_gene_variant 0.94 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.98 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.98 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.99 rifampicin Uncertain significance
nusG 734129 c.-125G>A upstream_gene_variant 0.99 rifampicin Uncertain significance
nusG 734147 c.-107T>C upstream_gene_variant 0.99 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 0.98 rifampicin
nusG 734175 c.-79_-77delGGTinsCTC upstream_gene_variant 0.99 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 0.99 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 0.99 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.99 rifampicin Uncertain significance
nusG 734192 c.-62G>C upstream_gene_variant 0.99 rifampicin
nusG 734201 c.-53G>T upstream_gene_variant 0.99 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 0.99 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.99 rifampicin
nusG 734223 c.-30_-28delGCT upstream_gene_variant 1.0 rifampicin
nusG 734231 c.-22_-21delGT upstream_gene_variant 1.0 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 1.0 rifampicin
nusG 734289 c.36G>A synonymous_variant 1.0 rifampicin
nusG 734352 c.99T>C synonymous_variant 1.0 rifampicin
nusG 734358 c.105C>G synonymous_variant 1.0 rifampicin
nusG 734359 p.Ala36Thr missense_variant 1.0 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734388 c.135G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734391 c.138C>A synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734448 c.195C>T synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734457 c.204C>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734544 c.291C>T synonymous_variant 1.0 rifampicin
nusG 734556 c.303C>T synonymous_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>C synonymous_variant 1.0 rifampicin
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734595 c.342C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734637 c.384G>C synonymous_variant 1.0 rifampicin
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734733 c.480T>C synonymous_variant 1.0 rifampicin
nusG 734742 c.489T>C synonymous_variant 1.0 rifampicin
nusG 734750 p.Ser166Thr missense_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734761 p.Ala170Thr missense_variant 1.0 rifampicin Uncertain significance
nusG 734772 c.519G>C synonymous_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734787 c.534T>C synonymous_variant 1.0 rifampicin
nusG 734790 c.537G>T synonymous_variant 1.0 rifampicin
nusG 734792 p.Val180Ala missense_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>G synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 1.0 rifampicin
nusG 734882 p.Ala210Gly missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734928 c.675A>G synonymous_variant 1.0 rifampicin
nusG 734931 c.678A>G synonymous_variant 1.0 rifampicin
nusG 734934 c.681G>C synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734941 c.688C>T synonymous_variant 1.0 rifampicin
nusG 734946 c.693C>G synonymous_variant 1.0 rifampicin
nusG 734949 c.696T>C synonymous_variant 1.0 rifampicin
nusG 734950 p.Gly233Ser missense_variant 1.0 rifampicin
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760185 c.379C>T synonymous_variant 1.0 rifampicin
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760271 c.465C>G synonymous_variant 1.0 rifampicin
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760313 c.507G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>C synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760496 c.690G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760577 c.771G>A synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 1.0 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760869 p.Val355Ile missense_variant 1.0 rifampicin Uncertain significance
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760938 c.1132C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.96 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761285 c.1479G>C synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 1.0 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761373 p.Val523His missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761436 c.1630_1632delGCGinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761440 p.Asp545Gly missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.97 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.96 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.97 rifampicin
rpoB 761531 c.1725C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761537 c.1731C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.99 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.98 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.99 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>T synonymous_variant 0.98 rifampicin
rpoB 761675 c.1869G>A synonymous_variant 0.98 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.98 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.96 rifampicin
rpoB 761714 c.1908C>G synonymous_variant 0.96 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 0.95 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.95 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 1.0 rifampicin
rpoB 761882 c.2076C>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761903 c.2097T>G synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.97 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762545 c.-825C>G upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.91 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 0.98 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.98 rifampicin
rpoC 763187 c.-183C>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.96 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.98 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.82 rifampicin
rpoC 763214 c.-156T>G upstream_gene_variant 0.98 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.98 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.97 rifampicin
rpoB 763272 c.3466C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763399 c.30C>T synonymous_variant 0.99 rifampicin
rpoC 763405 c.36C>T synonymous_variant 0.99 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.99 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.99 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 763711 c.342G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>T synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763729 c.360G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764134 c.765C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764191 c.822C>G synonymous_variant 1.0 rifampicin
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Ile missense_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764392 c.1023C>T synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>C synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 1.0 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764848 c.1479G>A synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639_1641delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>G synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>A synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765523 c.2154C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>C synonymous_variant 1.0 rifampicin
rpoC 765631 p.Asp754Glu missense_variant 1.0 rifampicin
rpoC 765655 c.2286T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365_2367delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.9 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.9 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.9 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766354 c.2985C>T synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 1.0 rifampicin
rpoC 766375 c.3006C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>T synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 1.0 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766618 c.3249G>C synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>T synonymous_variant 1.0 rifampicin
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766879 c.3510G>C synonymous_variant 1.0 rifampicin
rpoC 766882 c.3513C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.99 rifampicin Uncertain significance
rpoC 766888 c.3519G>C synonymous_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>G synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 1.0 rifampicin
rpoC 766984 c.3615G>C synonymous_variant 1.0 rifampicin
rpoC 766988 c.3619C>T synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767080 c.3711G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.99 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767194 c.3825C>G synonymous_variant 0.99 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.97 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpsL 781568 c.9C>G synonymous_variant 0.97 streptomycin
rpsL 781571 c.12C>T synonymous_variant 0.97 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.98 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.98 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.99 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.99 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781664 c.105C>T synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.99 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.99 streptomycin
rpsL 781817 c.258G>A synonymous_variant 1.0 streptomycin
rpsL 781820 c.261G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>A upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800789 c.-20G>A upstream_gene_variant 1.0 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 1.0 linezolid
rplC 800796 c.-13A>C upstream_gene_variant 1.0 linezolid
rplC 800801 c.-8_-6delACAinsT upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 0.97 linezolid
rplC 800808 c.-1delAinsTC upstream_gene_variant 1.0 linezolid
rplC 800815 c.7C>A synonymous_variant 0.97 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 1.0 linezolid
rplC 800877 c.69A>T synonymous_variant 1.0 linezolid
rplC 800880 c.72A>T synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800901 c.93C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>C synonymous_variant 1.0 linezolid
rplC 800931 c.123G>A synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800958 c.150G>T synonymous_variant 1.0 linezolid
rplC 800961 c.153G>A synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800985 c.177A>C synonymous_variant 1.0 linezolid
rplC 800994 c.186C>G synonymous_variant 1.0 linezolid
rplC 801004 p.Leu66Val missense_variant 1.0 linezolid
rplC 801009 c.201A>C synonymous_variant 1.0 linezolid
rplC 801020 p.Thr71Ser missense_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801136 p.Ser110Ala missense_variant 1.0 linezolid
rplC 801141 c.333C>T synonymous_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>A synonymous_variant 1.0 linezolid
rplC 801168 c.360C>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801195 c.387G>C synonymous_variant 1.0 linezolid
rplC 801210 c.402T>C synonymous_variant 1.0 linezolid
rplC 801219 c.411C>T synonymous_variant 1.0 linezolid
rplC 801231 c.423C>G synonymous_variant 1.0 linezolid
rplC 801249 c.441T>G synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>T synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801282 c.474G>T synonymous_variant 0.98 linezolid
rplC 801285 c.477G>T synonymous_variant 0.98 linezolid
rplC 801288 c.480G>C synonymous_variant 1.0 linezolid
rplC 801301 c.493C>A synonymous_variant 1.0 linezolid
rplC 801309 c.501C>G synonymous_variant 0.97 linezolid
rplC 801312 c.504G>C synonymous_variant 0.98 linezolid
rplC 801324 c.516T>C synonymous_variant 0.96 linezolid
rplC 801336 c.528C>G synonymous_variant 0.94 linezolid
rplC 801339 c.531T>C synonymous_variant 0.94 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.94 linezolid
rplC 801348 c.540T>G synonymous_variant 0.94 linezolid
rplC 801349 p.Leu181Val missense_variant 0.94 linezolid
rplC 801357 c.549T>C synonymous_variant 0.94 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.94 linezolid
rplC 801385 c.577C>T synonymous_variant 0.88 linezolid
rplC 801402 c.594T>C synonymous_variant 0.84 linezolid
rplC 801405 c.597T>C synonymous_variant 0.84 linezolid
rplC 801420 c.612A>C synonymous_variant 0.84 linezolid
rplC 801423 c.615G>C synonymous_variant 0.84 linezolid
rplC 801426 c.618C>G synonymous_variant 0.84 linezolid
rplC 801427 p.Met207Val missense_variant 0.85 linezolid
rplC 801438 c.630T>C synonymous_variant 0.84 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 0.82 linezolid
fbiC 1303431 c.501T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303458 c.528G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303479 c.549G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303542 c.612C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303554 c.624G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303650 c.720G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303665 c.735G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303698 c.768C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303746 p.Asp272Glu missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.99 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303857 c.927C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303866 p.Glu312Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303908 c.978C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303944 c.1014G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.8 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304826 c.1896G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304871 c.1941G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Glu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305006 p.Glu692Asp missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364904 p.Asp164Glu missense_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 1.0 pyrazinamide
sigE 1364935 p.Gln175Glu missense_variant 1.0 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 1.0 pyrazinamide
sigE 1364952 c.540A>G synonymous_variant 1.0 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 1.0 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 1.0 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364967 c.555C>T synonymous_variant 1.0 pyrazinamide
sigE 1364976 c.564T>G synonymous_variant 1.0 pyrazinamide
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365048 c.636G>A synonymous_variant 1.0 pyrazinamide
sigE 1365060 c.648C>G synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 1.0 pyrazinamide
sigE 1365078 c.666C>G synonymous_variant 1.0 pyrazinamide
sigE 1365081 c.669G>A synonymous_variant 1.0 pyrazinamide
Rv1258c 1406230 p.Thr371Ala missense_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406234 c.1107A>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
pyrazinamide
Rv1258c 1406245 p.Leu366Val missense_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406251 c.1090C>T synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406252 c.1089T>C synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406271 c.1069_1070insGATGT frameshift_variant&stop_gained 1.0 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406276 c.1060_1064delTCGCT frameshift_variant 1.0 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406297 c.1044A>G synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406315 p.Gln342His missense_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406318 c.1021_1023delGCAinsCG frameshift_variant&synonymous_variant 1.0 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406321 c.1020A>G synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406327 c.1014G>C synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406333 p.Ile336Met missense_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406336 c.1005G>C synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406345 c.996T>C synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406360 c.981C>G synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406363 c.978A>C synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406369 c.972G>C synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406379 p.Val321Thr missense_variant 1.0 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406385 p.Ala319Gly missense_variant 1.0 streptomycin
isoniazid
pyrazinamide
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460822 c.-223C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460841 c.-204C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460885 c.-160G>C upstream_gene_variant 1.0 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 1.0 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460906 c.-139G>T upstream_gene_variant 1.0 bedaquiline
atpE 1461086 c.42A>C synonymous_variant 1.0 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 1.0 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 1.0 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 1.0 bedaquiline
atpE 1461119 c.75T>C synonymous_variant 1.0 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 1.0 bedaquiline
atpE 1461132 c.88_90delGTCinsAT frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
atpE 1461261 c.217C>T synonymous_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473571 n.-87C>T upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473593 n.-65_-63delAATinsTAAAC upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473600 n.-58A>G upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473603 n.-55C>T upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473610 n.-47delT upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473613 n.-45G>A upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473627 n.-31T>G upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473628 n.-30_-29insTGAAA upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473633 n.-25C>T upstream_gene_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473637 n.-21delAinsTTC upstream_gene_variant 0.96 capreomycin
linezolid
rrl 1473653 n.-5_2delTGTGTTTinsGTGTAA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474995 n.1338T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475007 n.1350C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475017 n.1360_1361insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475609 n.1952C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476790 n.3134dupC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673877 c.-325C>G upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1673898 c.-304C>T upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.91 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.91 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673931 c.-271C>G upstream_gene_variant 0.93 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.94 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673961 c.-241A>T upstream_gene_variant 0.96 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 0.96 ethionamide
isoniazid
inhA 1673973 c.-229G>C upstream_gene_variant 0.96 ethionamide
isoniazid Uncertain significance
inhA 1673976 c.-226T>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673982 c.-220G>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1673991 c.-211C>T upstream_gene_variant 0.98 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.98 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.98 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 0.98 ethionamide
isoniazid
inhA 1674042 c.-160G>T upstream_gene_variant 0.98 ethionamide
isoniazid
fabG1 1674049 p.Gln204Glu missense_variant 0.98 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
fabG1 1674083 p.Ala215Glu missense_variant 1.0 ethionamide
isoniazid
fabG1 1674098 p.Val220Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674216 c.15G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674237 c.36T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674238 c.37_39delAGCinsTCG synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674279 c.78A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674280 p.Arg27Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674285 c.84A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674294 c.93G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674295 p.Gln32Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674309 c.108G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674315 c.114C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674318 c.117C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674321 c.120G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid
inhA 1674368 p.Ala56Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674382 p.Leu61Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1674399 c.198A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674428 p.Gly76Asp missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674436 p.Thr79Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674440 p.Glu80Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674443 p.Ala81Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674465 c.264C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674604 c.403C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674630 c.429C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674735 c.534G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674738 c.537C>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674765 c.564C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674799 c.598_600delAGTinsTCG synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674849 c.648G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674855 c.654C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674918 c.717C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674933 c.732G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674934 p.Leu245Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674939 c.738G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833517 c.-24delC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833610 c.69C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833771 p.Asn77Ser missense_variant 1.0 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.99 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.99 pyrazinamide
rpsA 1833995 c.454C>T synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834000 c.459G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.99 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834288 c.747C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834411 c.870T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834498 c.957C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834549 c.1008G>A synonymous_variant 0.99 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 1.0 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834846 c.1305C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834852 c.1311C>G synonymous_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 1.0 linezolid
tsnR 1853393 c.-213C>G upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 1.0 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.99 linezolid
tsnR 1853492 c.-114G>C upstream_gene_variant 0.99 linezolid
tsnR 1853504 c.-102C>G upstream_gene_variant 1.0 linezolid
tsnR 1853522 c.-84C>G upstream_gene_variant 1.0 linezolid
tsnR 1853528 c.-78G>C upstream_gene_variant 1.0 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 1.0 linezolid
tsnR 1853540 c.-66A>G upstream_gene_variant 1.0 linezolid
bacA 2062945 p.Ser595Thr missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062952 p.Leu593Met missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062955 c.1774T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062968 p.Phe587Tyr missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062971 c.1758G>A synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062980 p.Thr583Glu missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062998 p.Ser577Ala missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063001 c.1728A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063013 c.1716C>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063016 c.1713G>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063043 c.1686T>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063046 c.1683T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063055 c.1674T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063058 c.1671A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063067 c.1662T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063070 c.1659C>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063076 c.1653C>A synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063517 c.1212G>C synonymous_variant 0.91 streptomycin
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
bacA 2063523 c.1206T>C synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063529 c.1200A>G synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063538 c.1189_1191delGCAinsTG frameshift_variant&missense_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063541 c.1188A>G synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063544 c.1185C>G synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063552 p.Ser393Ala missense_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063553 c.1176G>C synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063556 c.1173T>C synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063588 c.1141T>C synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063592 c.1137C>T synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063595 p.His378Gln missense_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063598 c.1131T>C synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063607 c.1122C>T synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063612 p.Ser373Ala missense_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063613 c.1116T>G synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063619 p.Thr370Ser missense_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063625 c.1104G>A synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063631 c.1098T>C synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064963 c.-235G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064996 c.-268G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101783 c.1260T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101786 c.1257G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101808 p.Thr412Ser missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101812 p.Ile411Val missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101830 p.Ile405Val missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101837 p.Ala402Val missense_variant 1.0 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101867 c.1176C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101888 c.1153_1155delGTTinsCG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101891 c.1152C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101899 p.Ile382Val missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101915 c.1128T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101920 c.1123A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101927 c.1116G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101936 c.1107G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101954 c.1089G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101966 c.1077T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155650 c.462G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>C synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
pncA 2289930 c.-689A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289937 c.-696C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289943 c.-704_-702delTTTinsCG upstream_gene_variant 1.0 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289970 c.-731_-729delTTCinsCG upstream_gene_variant 1.0 pyrazinamide
pncA 2289973 c.-732T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289994 c.-753A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289997 c.-756G>T upstream_gene_variant 1.0 pyrazinamide
pncA 2290006 c.-765T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290021 c.-780C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 1.0 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290038 c.-797G>A upstream_gene_variant 1.0 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290071 c.-830A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290072 c.-831T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290075 c.-834C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290078 c.-837C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2290087 c.-846T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290108 c.-867C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290111 c.-870G>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290114 c.-873T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290122 c.-881A>G upstream_gene_variant 1.0 pyrazinamide
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.99 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.99 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.99 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.98 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.98 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.98 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.97 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.99 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.99 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.99 isoniazid
kasA 2518053 c.-62_-60delATTinsCG upstream_gene_variant 0.99 isoniazid
kasA 2518059 c.-56T>A upstream_gene_variant 0.99 isoniazid
kasA 2518073 c.-42T>C upstream_gene_variant 0.98 isoniazid
kasA 2518079 c.-36T>C upstream_gene_variant 0.97 isoniazid
kasA 2518088 c.-27T>C upstream_gene_variant 0.94 isoniazid
kasA 2518089 c.-26C>A upstream_gene_variant 0.92 isoniazid
kasA 2518120 c.6T>C synonymous_variant 1.0 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 1.0 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 1.0 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 1.0 isoniazid
kasA 2518162 c.48G>A synonymous_variant 1.0 isoniazid
kasA 2518174 c.60A>G synonymous_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518234 c.120G>A synonymous_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 0.96 isoniazid
kasA 2518282 c.168A>G synonymous_variant 1.0 isoniazid
kasA 2518283 c.169_171delGCGinsCC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518288 c.174C>G synonymous_variant 1.0 isoniazid
kasA 2518297 c.183C>G synonymous_variant 1.0 isoniazid
kasA 2518447 c.333T>G synonymous_variant 1.0 isoniazid
kasA 2518459 c.345T>G synonymous_variant 1.0 isoniazid
kasA 2518462 c.348A>C synonymous_variant 1.0 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518474 c.360G>A synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA