TB-Profiler result

Run: ERR3797015

Summary

Run ID: ERR3797015

Sample name:

Date: 2024-04-14T07:19:04.096410

Number of reads: 343115

Percentage reads mapped: 11.59

Median coverage: 2.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB


Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3.1.2.2 East-African-Indian RD750 0.06
lineage4 Euro-American None 0.97
lineage4.9 Euro-American (H37Rv-like) None 0.98
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser140Asn Uncertain significance Mutation from literature
c.316_318delGCGinsAC Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.508_510delGTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.709_711delCCCinsAA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.916_918delTTCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.952_954delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.961_963delGCGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1189_1191delAAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1585_1587delGCCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1825_1827delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1960_1961insCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1964_1965delGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491290 c.508_510delGTGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491491 c.709_711delCCCinsAA frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303882 c.952_954delGTTinsAC frameshift_variant&missense_variant 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303891 c.961_963delGCGinsAC frameshift_variant&missense_variant 0.79 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304119 c.1189_1191delAAAinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304515 c.1585_1587delGCCinsAT frameshift_variant&missense_variant 0.88 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304755 c.1825_1827delCTAinsTG frameshift_variant&stop_gained 0.87 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304890 c.1960_1961insCG frameshift_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304893 c.1964_1965delGC frameshift_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155693 p.Ser140Asn missense_variant 0.9 isoniazid Uncertain significance Mutation from literature
katG 2155794 c.316_318delGCGinsAC frameshift_variant&missense_variant 0.96 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 682 c.682T>C synonymous_variant 1.0 isoniazid
dnaA 690 c.690G>C synonymous_variant 1.0 isoniazid
dnaA 693 c.693A>C synonymous_variant 1.0 isoniazid
dnaA 702 c.702C>G synonymous_variant 1.0 isoniazid
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 762 c.763_767delAAGGT frameshift_variant 1.0 isoniazid Uncertain significance
dnaA 771 c.771delAinsGCGTCG frameshift_variant&synonymous_variant 1.0 isoniazid Uncertain significance
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 782 p.Ser261Thr missense_variant 1.0 isoniazid Uncertain significance
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 p.Glu280Asp missense_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.94 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.94 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.94 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.89 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.94 isoniazid
dnaA 900 c.900C>T synonymous_variant 0.89 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.94 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.94 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 933 c.933C>G synonymous_variant 0.94 isoniazid
dnaA 954 c.954G>C synonymous_variant 0.8 isoniazid
dnaA 955 c.955_957delAGAinsCC frameshift_variant&missense_variant 0.9 isoniazid Uncertain significance
dnaA 966 c.966T>C synonymous_variant 0.9 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.91 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6202 c.963C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6203 p.Ser322Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6775 c.-527G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554_1555delTAinsCCTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6796 c.1558_1559delGG frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7466 c.165G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7506 c.205_207delAGCinsGA frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7775 c.474C>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7823 c.522G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7868 p.Ile189Met missense_variant 0.86 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8168 c.867A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8190 p.Ala297Thr missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8228 c.927G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Val missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8462 c.1161A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Ser missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8591 c.1290C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8885 c.1584C>G synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.92 levofloxacin
moxifloxacin
fgd1 491049 c.267T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491055 c.273C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491248 p.Arg156Lys missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491251 p.Leu157Thr missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491320 p.Ala180Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491337 c.555C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 c.720G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491631 c.849C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575618 c.271C>A synonymous_variant 0.6 ethionamide
isoniazid
mshA 575652 p.Arg102Pro missense_variant 0.77 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.83 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575692 c.345G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.96 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575714 p.Tyr123Asn missense_variant 0.92 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.97 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.95 ethionamide
isoniazid Uncertain significance
mshA 575764 c.417C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.97 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575806 c.459G>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575818 c.471G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575824 c.477T>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575843 p.Arg166Ala missense_variant 0.9 ethionamide
isoniazid
mshA 575856 p.Ala170Gly missense_variant 0.88 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 575878 c.531A>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.85 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.84 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.84 ethionamide
isoniazid
mshA 575906 p.Ala187Ser missense_variant 0.8 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 0.75 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575924 c.577_579delGGAinsTC frameshift_variant&missense_variant 0.75 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575929 c.582C>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575932 c.585G>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 575939 p.Leu198Met missense_variant 0.75 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575945 p.Thr200Ser missense_variant 0.75 ethionamide
isoniazid
mshA 575948 p.Val201Ile missense_variant 0.75 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.9 ethionamide
isoniazid Not assoc w R - Interim
mshA 575974 c.627G>A synonymous_variant 0.9 ethionamide
isoniazid
mshA 575977 c.630G>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.9 ethionamide
isoniazid
ccsA 620337 c.447C>G synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620350 p.Arg154Lys missense_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620586 c.696C>A synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620589 c.699G>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620605 c.715_717delGTTinsAA frameshift_variant&missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
nusG 734484 c.231C>T synonymous_variant 0.9 rifampicin
nusG 734499 c.246G>C synonymous_variant 0.91 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760145 c.339C>T synonymous_variant 0.95 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>T synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760373 c.567C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760400 c.594G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.96 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.97 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.97 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.97 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 0.97 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760563 c.757delCinsAT frameshift_variant&synonymous_variant 0.96 rifampicin
rpoB 760566 p.Ser254Ala missense_variant 0.96 rifampicin
rpoB 760567 c.762delG frameshift_variant 0.96 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.97 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>A synonymous_variant 0.96 rifampicin
rpoB 760649 c.843G>C synonymous_variant 0.96 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.92 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760712 c.906G>C synonymous_variant 0.96 rifampicin
rpoB 760715 c.909C>G synonymous_variant 0.96 rifampicin
rpoB 760721 c.915C>G synonymous_variant 0.96 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.93 rifampicin
rpoB 760965 c.1159_1161delATGinsCC frameshift_variant&missense_variant 0.93 rifampicin
rpoB 760973 c.1167G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 1.0 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 0.97 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761075 c.1269G>A synonymous_variant 0.95 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761175 c.1369C>T synonymous_variant 0.96 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761217 c.1411_1413delCCGinsTC frameshift_variant&missense_variant 0.94 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761346 p.Val514Ile missense_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Asp missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.94 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.92 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.95 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.92 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.88 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 0.92 rifampicin
rpoB 761718 p.Ala638Thr missense_variant 0.91 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762078 c.2272C>T synonymous_variant 0.96 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762287 c.2481C>G synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>T synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.98 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.96 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.96 rifampicin Uncertain significance
rpoC 762533 c.-837T>C upstream_gene_variant 0.95 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.95 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.95 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.95 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.9 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762917 c.-453C>T upstream_gene_variant 1.0 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.97 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 0.94 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 0.94 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.9 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.91 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763200 c.3394_3396delCTAinsTG frameshift_variant&stop_gained 1.0 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-163delAGinsTC upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 1.0 rifampicin
rpoB 763265 c.3459G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763274 c.-96G>C upstream_gene_variant 1.0 rifampicin
rpoC 763411 c.42T>C synonymous_variant 1.0 rifampicin
rpoC 763414 c.45T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 0.93 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.93 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 1.0 rifampicin
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>T synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.97 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.97 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763771 c.402C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.97 rifampicin
rpoC 763787 p.Asp140Asn missense_variant 0.97 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763822 c.453C>G synonymous_variant 1.0 rifampicin
rpoC 763825 c.456G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763837 c.468G>C synonymous_variant 1.0 rifampicin
rpoC 763840 c.471G>C synonymous_variant 1.0 rifampicin
rpoC 763852 c.483C>G synonymous_variant 1.0 rifampicin
rpoC 763853 p.Val162Ile missense_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763861 c.492C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.94 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.94 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.94 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.94 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.92 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.92 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.92 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>G synonymous_variant 0.94 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.94 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764843 p.Ala492Ser missense_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.97 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>T synonymous_variant 0.92 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.92 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.92 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765445 c.2076G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.93 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765466 c.2097C>T synonymous_variant 0.73 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765856 c.2487T>C synonymous_variant 0.81 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.86 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.96 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765898 c.2529C>T synonymous_variant 0.88 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.95 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 0.93 rifampicin
rpoC 766012 c.2643C>A synonymous_variant 0.9 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.81 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 0.87 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.88 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.82 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.82 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766425 c.3056_3057insTGTCAC disruptive_inframe_insertion 0.85 rifampicin
rpoC 766428 p.Val1020Gly missense_variant 0.85 rifampicin
rpoC 766434 p.Glu1022Ala missense_variant 0.85 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 0.88 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 0.89 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 0.8 rifampicin
rpoC 766517 p.Thr1050Ser missense_variant 0.6 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.83 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.87 rifampicin
rpoC 766703 p.Met1112Leu missense_variant 0.9 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766726 c.3357T>C synonymous_variant 0.95 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.95 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.96 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.96 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.96 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.89 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.85 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.85 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766920 p.Ala1184Gly missense_variant 0.85 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.94 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>A synonymous_variant 0.97 rifampicin
rpoC 767152 c.3783T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.97 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.94 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767269 c.3900C>G synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
mmpL5 775856 c.2625T>C synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Thr missense_variant 0.54 clofazimine
bedaquiline
mmpL5 775871 p.Ile870Met missense_variant 0.57 clofazimine
bedaquiline
mmpL5 775880 p.Asn867Lys missense_variant 0.67 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.67 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775907 c.2574C>G synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 775910 c.2571G>C synonymous_variant 0.57 clofazimine
bedaquiline
mmpL5 775919 c.2560_2562delCTGinsGC frameshift_variant&missense_variant 0.56 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775924 c.2557C>T synonymous_variant 0.36 clofazimine Not assoc w R - Interim
bedaquiline
mmpL5 775940 c.2541C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775972 p.Ala837Pro missense_variant 0.87 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.74 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776015 c.2464_2466delATCinsGG frameshift_variant&missense_variant 0.86 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776039 c.2442C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776048 c.2433G>C synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 0.58 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781586 c.27C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781628 c.69T>A synonymous_variant 1.0 streptomycin
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781634 c.75G>A synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781679 c.120C>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.96 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.95 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.95 streptomycin
rpsL 781725 p.Lys56Arg missense_variant 0.95 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.95 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.95 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.95 streptomycin
rpsL 781737 p.Gln60Ala missense_variant 0.95 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.96 streptomycin
rpsL 781754 c.195G>A synonymous_variant 0.92 streptomycin Not assoc w R - Interim
rpsL 781760 c.201T>C synonymous_variant 0.92 streptomycin
rpsL 781769 c.210G>A synonymous_variant 0.93 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.95 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.97 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.97 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.97 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.96 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.96 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.98 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.98 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.98 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.98 streptomycin
rpsL 781895 c.336G>A synonymous_variant 0.98 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.98 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.98 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.98 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.93 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.92 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.96 linezolid
rplC 800549 c.-260G>T upstream_gene_variant 0.92 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.96 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.92 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.92 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 0.92 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.96 linezolid
rplC 800585 c.-224T>A upstream_gene_variant 0.92 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.92 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.92 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 0.96 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.93 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.97 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.97 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.96 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.96 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.96 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.96 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.96 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.97 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.97 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.97 linezolid
rplC 800753 c.-56C>T upstream_gene_variant 0.96 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.96 linezolid
rplC 800796 c.-12_-9delTTGG upstream_gene_variant 0.94 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 0.94 linezolid
rplC 800808 c.-1A>C upstream_gene_variant 0.94 linezolid Uncertain significance
rplC 800815 c.7C>A synonymous_variant 0.94 linezolid
rplC 800820 c.12G>A synonymous_variant 0.94 linezolid
rplC 800829 c.21C>G synonymous_variant 0.94 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800873 p.Arg22Lys missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800892 c.84G>C synonymous_variant 1.0 linezolid
rplC 800910 c.102C>T synonymous_variant 0.93 linezolid
rplC 800913 c.105G>C synonymous_variant 0.92 linezolid
rplC 800916 c.108A>G synonymous_variant 0.92 linezolid
rplC 800919 c.111C>G synonymous_variant 0.92 linezolid
rplC 800928 c.120C>T synonymous_variant 0.92 linezolid
rplC 800931 c.123G>C synonymous_variant 0.91 linezolid
rplC 800934 c.126C>G synonymous_variant 0.91 linezolid
rplC 800937 c.129A>G synonymous_variant 0.91 linezolid
rplC 800940 c.132C>T synonymous_variant 0.91 linezolid
rplC 800949 c.141T>C synonymous_variant 0.83 linezolid
fbiC 1303492 c.562T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303497 c.567G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303519 c.589_590delAGinsTC synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303536 c.606G>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303653 c.723G>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303866 p.Glu312Asp missense_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303871 p.Tyr314Phe missense_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303881 c.951G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303903 p.Leu325Met missense_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303951 p.Asp341Ser missense_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303977 c.1047C>A synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>A synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304058 c.1128G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304103 c.1173G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304106 c.1176G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304109 c.1179C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304151 c.1221C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304481 c.1551T>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304487 c.1557C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304502 c.1572G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304503 c.1573C>T synonymous_variant 0.88 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304514 c.1584T>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304547 c.1617C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304652 c.1722C>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304688 p.Asp586Glu missense_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304709 c.1779C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304871 c.1941G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304877 c.1947T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304880 c.1950C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304919 c.1989C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305001 p.Ile691Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305007 p.Ile693Val missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305043 c.2113_2115delTCAinsAGC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364676 c.264C>G synonymous_variant 0.95 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 0.96 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 0.96 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.96 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.96 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 0.96 pyrazinamide
sigE 1364716 c.304_306delCTCinsTG frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
sigE 1364721 c.309C>G synonymous_variant 0.96 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 0.96 pyrazinamide
sigE 1364751 c.339C>G synonymous_variant 0.89 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.89 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.96 pyrazinamide
sigE 1364767 c.355_357delAGGinsCC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
sigE 1364784 c.372C>G synonymous_variant 0.97 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.97 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.93 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.93 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.98 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 0.92 pyrazinamide Uncertain significance
sigE 1364835 c.423C>G synonymous_variant 0.97 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.97 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.92 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.91 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 0.94 pyrazinamide
sigE 1364865 c.453G>T synonymous_variant 0.97 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.94 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.98 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 0.96 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.98 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.96 pyrazinamide
sigE 1364950 c.538_540delGCAinsTC frameshift_variant&missense_variant 0.97 pyrazinamide Uncertain significance
sigE 1364958 c.546G>C synonymous_variant 1.0 pyrazinamide
sigE 1364961 c.549A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>G synonymous_variant 1.0 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
sigE 1364992 c.580_582delCCGinsGC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.94 pyrazinamide
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>T non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473813 n.156C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_644delTCCTTTTCCTCTCCGinsCTCCTTC non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474421 n.764_767delGCGCinsA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474630 n.973T>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474631 n.974G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474636 n.979A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053delTinsACAC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474718 n.1061A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474720 n.1065_1066delTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475324 n.1667G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475376 n.1719A>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid Uncertain significance
rrl 1475380 n.1723C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475387 n.1730C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475397 n.1740G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475403 n.1746T>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475406 n.1749T>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476744 n.3087G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476755 n.3098G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673646 c.-556T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673658 c.-544G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673673 c.-529C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673706 c.-496C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1673718 c.-484G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673750 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
fabG1 1673755 p.Glu106Gln missense_variant 1.0 ethionamide
isoniazid
fabG1 1673767 p.Asn110Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1673772 c.-430C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673778 c.-424C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673784 c.-418G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673787 c.-415G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673937 c.-265G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673967 c.-235G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674435 c.234G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674440 p.Glu80Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674443 p.Ala81Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674483 c.282G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674498 c.297G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 0.88 ethionamide
isoniazid
inhA 1674621 c.420C>G synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 0.8 ethionamide
isoniazid
inhA 1674639 c.438C>G synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.85 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674669 c.468G>T synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCA frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674745 p.Tyr182Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674765 c.564C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674819 c.618G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674840 c.639C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674855 c.654C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 c.682_684delATCinsCG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674927 c.726G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674937 p.Leu246Met missense_variant 0.94 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674949 c.748C>T synonymous_variant 0.93 ethionamide
isoniazid
rpsA 1833578 p.Val13Ile missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833868 c.327C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833877 c.336C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612_613delTAinsCCAGCTC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616_621delTTGCAAinsC frameshift_variant&synonymous_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.96 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834573 c.1032G>A synonymous_variant 0.94 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.97 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834649 p.Thr370Ser missense_variant 0.94 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 p.Glu399Asp missense_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.97 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.97 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834776 p.Ala412Asp missense_variant 0.97 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834828 c.1287C>T synonymous_variant 0.92 pyrazinamide
katG 2155668 c.444G>C synonymous_variant 0.69 isoniazid
katG 2155676 c.436C>A synonymous_variant 0.71 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.95 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.73 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.33 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.92 isoniazid
katG 2155728 c.384G>T synonymous_variant 0.85 isoniazid
katG 2155740 p.Gly124Ala missense_variant 0.68 isoniazid Uncertain significance
katG 2155743 c.369G>T synonymous_variant 1.0 isoniazid
katG 2155765 p.His116Ser missense_variant 0.89 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.68 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.68 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.67 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.96 isoniazid
katG 2155806 c.306T>C synonymous_variant 0.94 isoniazid
katG 2155809 c.303G>T synonymous_variant 0.56 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.92 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.91 isoniazid
kasA 2519105 p.Cys331Val missense_variant 1.0 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 1.0 isoniazid
kasA 2519113 p.Gln333His missense_variant 1.0 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 1.0 isoniazid
kasA 2519161 c.1047G>C synonymous_variant 1.0 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 1.0 isoniazid
kasA 2519170 c.1056G>C synonymous_variant 1.0 isoniazid
kasA 2519179 c.1065G>T synonymous_variant 1.0 isoniazid
kasA 2519181 p.Val356Ala missense_variant 1.0 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 1.0 isoniazid
kasA 2519195 c.1081_1083delACGinsGC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519209 c.1095C>A synonymous_variant 1.0 isoniazid
kasA 2519224 c.1110C>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>G synonymous_variant 1.0 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 1.0 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 1.0 isoniazid
folC 2747272 c.327G>C synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747287 c.310_312delCCGinsGC frameshift_variant&missense_variant 0.91 para-aminosalicylic_acid
folC 2747290 c.309A>C synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747311 c.288C>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747317 c.282C>A synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsCG frameshift_variant&missense_variant 0.82 para-aminosalicylic_acid
folC 2747346 c.253C>T synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747349 p.Ala84Ser missense_variant 0.82 para-aminosalicylic_acid
Rv2477c 2782465 c.1578G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782480 c.1563G>A synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782486 c.1557G>A synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782496 p.Asp516Ser missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.92 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1486_1488delTCGinsAGC synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782586 p.Leu486Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782602 c.1441C>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782606 c.1435_1437delGGTinsAC frameshift_variant&missense_variant 0.96 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782612 c.1431T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782618 c.1425C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782624 c.1419G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782651 c.1392T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782759 c.1284A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782771 c.1272C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782774 c.1269G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782777 c.1266A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782786 c.1257A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782790 p.Thr418Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782792 c.1251A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782803 p.Gln414Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782807 c.1236T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782816 c.1227T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782840 c.1203C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782852 c.1191T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782894 c.1149C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782909 c.1134C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782912 p.Ser377Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782924 c.1119G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783014 p.Ser343Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783026 c.1017C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783086 c.957C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783101 c.942G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783107 c.936G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783432 p.Ser204Asp missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783506 c.537C>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783523 c.520C>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783524 c.519G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin