TB-Profiler result

Run: ERR405219
Summary

Run ID: ERR405219

Sample name:

Date: 2024-04-16T09:46:52.849726

Number of reads: 869906

Percentage reads mapped: 16.95

Median coverage: 13.0

Strain: La1.7;lineage3.1;lineage4

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.7 M.bovis None 0.14
lineage4 Euro-American None 0.16
lineage3.1 East-African-Indian RD750 0.57
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser140Asn Uncertain significance Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.778_780delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2077_2079delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1303708 c.778_780delTTGinsCC frameshift_variant&missense_variant 0.5 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsAG frameshift_variant&missense_variant 0.59 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 0.38 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305007 c.2077_2079delATCinsGG frameshift_variant&missense_variant 0.65 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155693 p.Ser140Asn missense_variant 0.8 isoniazid Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.64 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.62 isoniazid
dnaA 765 c.766_767insCG frameshift_variant 0.56 isoniazid Uncertain significance
dnaA 769 c.770_771delCA frameshift_variant 0.55 isoniazid Uncertain significance
dnaA 783 c.783C>T synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.62 isoniazid Uncertain significance
dnaA 805 c.805T>C synonymous_variant 0.63 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.63 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.61 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.63 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.63 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.62 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.63 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.62 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.66 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.69 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.7 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.68 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.64 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.62 isoniazid
gyrB 6100 c.861G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6204 p.Ser322Thr missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.8 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 6565 c.-737G>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.54 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.72 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.74 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6838 c.-464C>A upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7355 c.54T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 7415 c.114C>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7418 c.117C>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7694 c.393A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7763 c.462T>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8120 c.819G>A synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 8252 c.951G>A synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8279 c.978G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.79 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8357 c.1056G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8402 p.Asp367Glu missense_variant 0.67 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8405 c.1104C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8636 c.1335A>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8930 c.1629C>T synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.79 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.8 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9056 c.1755C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 9114 c.1813_1815delGAGinsAC frameshift_variant&missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9174 c.1873C>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9206 c.1905C>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9207 p.Lys636Arg missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 9210 c.1909C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9254 c.1953C>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9332 p.Asn677Lys missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9389 c.2088C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.47 isoniazid
fgd1 491547 c.765A>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491605 c.823C>T synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491631 c.849C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
mshA 575539 c.192C>T synonymous_variant 0.48 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575548 c.201C>G synonymous_variant 0.58 ethionamide
isoniazid
mshA 575557 c.210C>G synonymous_variant 0.58 ethionamide
isoniazid
mshA 575561 c.214_216delATGinsGA frameshift_variant&missense_variant 0.58 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575569 c.222A>G synonymous_variant 0.57 ethionamide
isoniazid
mshA 575572 c.225T>C synonymous_variant 0.57 ethionamide
isoniazid
mshA 575582 p.Leu79Met missense_variant 0.57 ethionamide
isoniazid
mshA 575587 c.240C>G synonymous_variant 0.63 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.57 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.59 ethionamide
isoniazid
mshA 575597 p.Ile84Val missense_variant 0.6 ethionamide
isoniazid
mshA 575620 c.273G>C synonymous_variant 0.56 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.43 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.52 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.73 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.72 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.75 ethionamide
isoniazid Uncertain significance
mshA 575767 c.420G>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.74 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.78 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 0.79 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575878 c.531A>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 0.64 ethionamide
isoniazid
ccsA 620388 c.498A>G synonymous_variant 0.42 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.42 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.56 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.58 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620451 c.561G>C synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620456 p.Ala189Gly missense_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>A synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>C synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>G synonymous_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>G synonymous_variant 0.85 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620781 c.891C>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
Rv0565c 657613 c.-143G>A upstream_gene_variant 0.64 ethionamide
Rv0565c 657620 c.-150C>T upstream_gene_variant 0.74 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.74 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.77 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.8 ethionamide
Rv0565c 657670 c.-200A>G upstream_gene_variant 0.71 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.71 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.71 ethionamide
Rv0565c 657686 c.-216C>T upstream_gene_variant 0.69 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.68 ethionamide
Rv0565c 657703 c.-233C>A upstream_gene_variant 0.63 ethionamide
Rv0565c 657722 c.-254_-252delAACinsCG upstream_gene_variant 0.31 ethionamide
Rv0565c 657732 c.-262G>C upstream_gene_variant 0.3 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.27 ethionamide
hadA 731732 c.-198G>C upstream_gene_variant 0.47 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.58 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.62 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.68 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.68 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.7 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.7 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.69 isoniazid
hadA 731825 c.-105G>C upstream_gene_variant 0.67 isoniazid
nusG 734421 c.168A>C synonymous_variant 0.62 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.65 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.76 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.78 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.82 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.84 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.93 rifampicin
nusG 734508 c.255C>G synonymous_variant 0.92 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.78 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.68 rifampicin
nusG 734574 c.321C>T synonymous_variant 0.64 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
nusG 734820 c.567A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 0.71 rifampicin
nusG 734841 c.588G>C synonymous_variant 0.73 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.73 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.73 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.73 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.73 rifampicin
nusG 734859 c.606G>C synonymous_variant 0.77 rifampicin
nusG 734863 p.Thr204Ser missense_variant 0.74 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.78 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.75 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.69 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.64 rifampicin
nusG 734922 c.669C>T synonymous_variant 0.43 rifampicin
nusG 734925 c.672C>T synonymous_variant 0.42 rifampicin
nusG 734928 c.675A>G synonymous_variant 0.42 rifampicin
nusG 734950 p.Gly233Asn missense_variant 0.47 rifampicin
nusG 734955 c.702A>G synonymous_variant 0.41 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.77 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.79 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.89 rifampicin Uncertain significance
rpoB 760181 c.375T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 0.83 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.94 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.93 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.91 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.91 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.89 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 0.91 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.88 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.8 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.8 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.85 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.82 rifampicin
rpoB 760508 c.702G>C synonymous_variant 0.84 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.85 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.82 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.76 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760551 c.745_746delTCinsAG synonymous_variant 0.71 rifampicin
rpoB 760563 c.757delCinsAT frameshift_variant&synonymous_variant 0.55 rifampicin
rpoB 760566 p.Ser254Ala missense_variant 0.5 rifampicin
rpoB 760567 c.762delG frameshift_variant 0.52 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.58 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.69 rifampicin
rpoB 760625 c.819C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.8 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.52 rifampicin
rpoB 760965 c.1159_1161delATGinsCC frameshift_variant&missense_variant 0.5 rifampicin
rpoB 760973 c.1167G>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 760979 c.1173G>A synonymous_variant 0.43 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.43 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.68 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.68 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.68 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.67 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.71 rifampicin
rpoB 761347 p.Val514Glu missense_variant 0.66 rifampicin
rpoB 761349 p.Asp515Asn missense_variant 0.7 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.7 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.74 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.71 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.72 rifampicin
rpoB 761381 c.1575G>C synonymous_variant 0.69 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.58 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.75 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.74 rifampicin
rpoB 761636 c.1830G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.7 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.68 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.59 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.5 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.57 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.59 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.58 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.62 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.59 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.59 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.56 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.59 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.52 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.76 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.8 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762068 c.2262C>T synonymous_variant 0.83 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.76 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.74 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.75 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.76 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 0.84 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 0.63 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.63 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 0.62 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.48 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 0.48 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.5 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.45 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.45 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.45 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.48 rifampicin
rpoB 762359 c.2553C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 0.41 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.41 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.44 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.56 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.44 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.5 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.5 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.82 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.79 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.77 rifampicin Uncertain significance
rpoC 762530 c.-840C>T upstream_gene_variant 0.77 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.78 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.75 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.75 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.73 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.68 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.68 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.6 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.6 rifampicin
rpoC 762827 c.-543G>A upstream_gene_variant 0.53 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.66 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.8 rifampicin
rpoB 762923 c.3117C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.84 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.95 rifampicin Not assoc w R
rpoB 763040 c.3234C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 0.83 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763082 c.-288C>G upstream_gene_variant 0.82 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.8 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.8 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.8 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763200 c.3394_3396delCTAinsTG frameshift_variant&stop_gained 0.68 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.64 rifampicin
rpoC 763206 c.-164_-163delAGinsTC upstream_gene_variant 0.64 rifampicin
rpoC 763217 c.-153G>C upstream_gene_variant 0.68 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.67 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.67 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.65 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.62 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.62 rifampicin
rpoC 763259 c.-111G>T upstream_gene_variant 0.52 rifampicin
rpoB 763265 c.3459G>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>G synonymous_variant 0.65 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.68 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.68 rifampicin
rpoC 763420 c.51G>C synonymous_variant 0.68 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.68 rifampicin Uncertain significance
rpoC 763429 c.60C>T synonymous_variant 0.72 rifampicin
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763435 c.66A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763501 c.132C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.84 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.78 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.83 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.8 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.8 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763774 c.405G>C synonymous_variant 0.79 rifampicin
rpoC 763781 p.Ser138Asp missense_variant 0.72 rifampicin
rpoC 763787 p.Asp140Asn missense_variant 0.72 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.74 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.7 rifampicin
rpoC 763819 c.450G>C synonymous_variant 0.67 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.53 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.39 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.48 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.52 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.58 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.58 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.61 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.65 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.66 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 0.65 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.65 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.65 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 0.6 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.52 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.48 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.44 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.41 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.47 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.47 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.63 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.68 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.66 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.67 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764153 p.Gln262Lys missense_variant 0.78 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.76 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.67 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 0.4 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.4 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.4 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.4 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.4 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.4 rifampicin
rpoC 764227 c.858G>T synonymous_variant 0.7 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.73 rifampicin
rpoC 764254 c.885G>A synonymous_variant 0.7 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.67 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.65 rifampicin
rpoC 764278 c.909_912delACAGinsGACGAA frameshift_variant&missense_variant 0.69 rifampicin
rpoC 764283 c.916_917delGG frameshift_variant 0.7 rifampicin
rpoC 764296 c.927G>C synonymous_variant 0.8 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.85 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.87 rifampicin
rpoC 764429 c.1060C>T synonymous_variant 0.87 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.84 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.85 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.85 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.86 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.9 rifampicin
rpoC 764491 c.1122G>C synonymous_variant 0.9 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.87 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 0.88 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>A synonymous_variant 0.75 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>T synonymous_variant 0.8 rifampicin
rpoC 764665 c.1296C>G synonymous_variant 0.82 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>T synonymous_variant 0.84 rifampicin
rpoC 764677 c.1308C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 0.84 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.81 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.8 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764857 c.1488G>T synonymous_variant 0.73 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.66 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.58 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.65 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.65 rifampicin Uncertain significance
rpoC 764920 c.1551G>C synonymous_variant 0.62 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764926 c.1557C>T synonymous_variant 0.64 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.64 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.64 rifampicin
rpoC 764956 c.1587T>C synonymous_variant 0.67 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>T synonymous_variant 0.62 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.62 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.68 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765379 c.2010G>C synonymous_variant 0.47 rifampicin
rpoC 765403 c.2034_2035insAT frameshift_variant 0.68 rifampicin
rpoC 765406 c.2037G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765407 c.2039_2040delGT frameshift_variant 0.65 rifampicin
rpoC 765419 p.Val684Ile missense_variant 0.7 rifampicin Uncertain significance
rpoC 765425 p.Lys686Glu missense_variant 0.72 rifampicin
rpoC 765452 p.Ala695Arg missense_variant 0.77 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.75 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.74 rifampicin Uncertain significance
rpoC 765493 c.2124G>C synonymous_variant 0.76 rifampicin
rpoC 765499 c.2130C>A synonymous_variant 0.76 rifampicin
rpoC 765529 c.2160C>T synonymous_variant 0.74 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.75 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.69 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.71 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.71 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.69 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.59 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.62 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.68 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765812 c.2443C>A synonymous_variant 0.68 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.83 rifampicin Uncertain significance
rpoC 765883 c.2514C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 0.79 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.71 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765958 c.2589C>G synonymous_variant 0.64 rifampicin
rpoC 765961 c.2592G>A synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.6 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 0.55 rifampicin
rpoC 766009 c.2640G>T synonymous_variant 0.4 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.27 rifampicin
rpoC 766095 p.Thr909Ser missense_variant 0.29 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.27 rifampicin
rpoC 766276 c.2907C>G synonymous_variant 0.27 rifampicin
rpoC 766277 c.2908_2910delACCinsTG frameshift_variant&missense_variant 0.27 rifampicin
rpoC 766280 p.Ser971Ala missense_variant 0.27 rifampicin
rpoC 766297 c.2928G>C synonymous_variant 0.5 rifampicin
rpoC 766299 p.Thr977Met missense_variant 0.48 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 0.6 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.62 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.69 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 0.79 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.78 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.81 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.82 rifampicin
rpoC 766423 c.3054T>C synonymous_variant 0.76 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.79 rifampicin
rpoC 766429 c.3060C>G synonymous_variant 0.79 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.73 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 0.72 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 0.66 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.67 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.66 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 0.68 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 0.66 rifampicin
rpoC 766517 p.Thr1050Ser missense_variant 0.76 rifampicin
rpoC 766525 c.3156G>T synonymous_variant 0.74 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.74 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.75 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.79 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.79 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.82 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 0.86 rifampicin
rpoC 766573 c.3204T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.86 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.82 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.82 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 0.82 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.8 rifampicin
rpoC 766634 p.Phe1089Ile missense_variant 0.78 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.75 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.73 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.67 rifampicin
rpoC 766658 c.3289_3291delCGGinsGC frameshift_variant&missense_variant 0.71 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.62 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.64 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766720 c.3351C>T synonymous_variant 0.73 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.79 rifampicin
rpoC 766732 c.3363G>C synonymous_variant 0.79 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.81 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.77 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.73 rifampicin
rpoC 766753 c.3384C>T synonymous_variant 0.74 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.7 rifampicin
rpoC 766776 p.Arg1136His missense_variant 0.7 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.61 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.55 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.55 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.53 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.57 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.4 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.36 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766931 c.3562_3564delGCAinsTG frameshift_variant&stop_gained 0.32 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.66 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.86 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.81 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.74 rifampicin
rpoC 767269 c.3900C>G synonymous_variant 0.81 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.81 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767302 c.3933C>A synonymous_variant 0.74 rifampicin
mmpL5 775874 c.2607C>G synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 775886 c.2595A>G synonymous_variant 0.69 clofazimine
bedaquiline
mmpL5 775889 c.2592C>G synonymous_variant 0.69 clofazimine
bedaquiline
mmpL5 775892 p.His863Pro missense_variant 0.69 clofazimine
bedaquiline
mmpL5 775907 c.2574C>G synonymous_variant 0.41 clofazimine
bedaquiline
mmpL5 775910 c.2571G>C synonymous_variant 0.42 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 0.42 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>C synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.35 clofazimine
bedaquiline
mmpL5 775922 c.2559G>C synonymous_variant 0.43 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.26 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.51 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.64 clofazimine
bedaquiline
mmpL5 775975 p.Leu836Met missense_variant 0.79 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.79 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 775997 c.2484T>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.76 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 0.81 clofazimine
bedaquiline
mmpL5 776021 c.2460G>A synonymous_variant 0.82 clofazimine
bedaquiline
mmpL5 776024 c.2457G>C synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 0.84 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 776075 c.2406C>G synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 776080 p.Ala801Ser missense_variant 0.71 clofazimine
bedaquiline
mmpL5 776084 c.2397C>G synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 776087 c.2394C>G synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 0.98 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776104 p.Ile793Leu missense_variant 0.65 clofazimine
bedaquiline
mmpL5 776126 p.Cys785Ala missense_variant 0.38 clofazimine
bedaquiline
mmpL5 776132 c.2347_2349delGCAinsTG frameshift_variant&missense_variant 0.39 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776137 p.Ser782Ala missense_variant 0.39 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776142 p.Gly780Ala missense_variant 0.4 clofazimine
bedaquiline
mmpL5 776152 p.Met777Leu missense_variant 0.35 clofazimine
bedaquiline
mmpL5 776155 c.2326T>C synonymous_variant 0.34 clofazimine
bedaquiline
mmpL5 776159 c.2322T>C synonymous_variant 0.34 clofazimine
bedaquiline
mmpL5 776175 p.Ser769Asn missense_variant 0.43 clofazimine
bedaquiline
mmpL5 776179 p.Leu768Met missense_variant 0.44 clofazimine
bedaquiline
mmpL5 776195 c.2286G>C synonymous_variant 0.38 clofazimine Not assoc w R - Interim
bedaquiline
mmpL5 776199 p.Thr761Ser missense_variant 0.33 clofazimine
bedaquiline
mmpL5 776681 c.1800G>C synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 776682 c.1798_1799insGA frameshift_variant 0.68 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776686 c.1793_1794delGG frameshift_variant 0.7 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776704 p.Asp593Asn missense_variant 0.68 clofazimine
bedaquiline
mmpL5 776715 p.Lys589Pro missense_variant 0.72 clofazimine
bedaquiline
mmpL5 777182 c.1299C>A synonymous_variant 0.46 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.38 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.38 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.35 clofazimine
bedaquiline
mmpL5 777209 c.1272C>T synonymous_variant 0.35 clofazimine
bedaquiline
mmpL5 777212 c.1269C>G synonymous_variant 0.35 clofazimine
bedaquiline
mmpL5 777218 c.1263G>T synonymous_variant 0.35 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781559 c.-1G>C upstream_gene_variant 0.63 streptomycin
rpsL 781572 c.13_15delCAGinsAC frameshift_variant&missense_variant 0.64 streptomycin Uncertain significance
rpsL 781595 c.36T>C synonymous_variant 0.76 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.76 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.77 streptomycin
rpsL 781616 c.57C>G synonymous_variant 0.85 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.88 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.88 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.87 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.88 streptomycin
rpsL 781676 c.117C>G synonymous_variant 0.9 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.88 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.88 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.88 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.87 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.87 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.85 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.85 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.88 streptomycin
rpsL 781754 c.195G>A synonymous_variant 0.88 streptomycin Not assoc w R - Interim
rpsL 781760 c.201T>C synonymous_variant 0.89 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.89 streptomycin Not assoc w R - Interim
rpsL 781811 c.252C>T synonymous_variant 0.85 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.86 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.86 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.85 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.85 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.87 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.79 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.78 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.78 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.72 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.68 streptomycin
rpsL 781895 c.336G>A synonymous_variant 0.66 streptomycin
rpsL 781898 c.339A>G synonymous_variant 0.66 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.69 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.68 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.63 streptomycin Uncertain significance
rplC 800594 c.-215C>G upstream_gene_variant 0.64 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.64 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.67 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.66 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.72 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.76 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.77 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.78 linezolid
rplC 800672 c.-137G>T upstream_gene_variant 0.8 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.8 linezolid
rplC 800693 c.-116A>T upstream_gene_variant 0.82 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.84 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.85 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.82 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.82 linezolid
rplC 800780 c.-29C>G upstream_gene_variant 0.74 linezolid
rplC 800797 c.-12_-8delTTGGAinsC upstream_gene_variant 0.62 linezolid
rplC 800803 c.-6A>C upstream_gene_variant 0.62 linezolid
rplC 800804 c.-5G>A upstream_gene_variant 0.59 linezolid
rplC 800807 c.-2C>A upstream_gene_variant 0.59 linezolid
rplC 800817 c.9A>T synonymous_variant 0.67 linezolid
rplC 800820 c.12G>A synonymous_variant 0.67 linezolid
rplC 800829 c.21C>G synonymous_variant 0.67 linezolid
rplC 800832 c.24T>C synonymous_variant 0.67 linezolid
rplC 800844 c.36T>C synonymous_variant 0.62 linezolid
rplC 800856 c.48A>G synonymous_variant 0.37 linezolid
rplC 800985 c.177A>C synonymous_variant 0.5 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 0.9 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1303695 c.765T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303701 c.771C>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303716 c.786C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303746 p.Asp272Glu missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>T synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303932 c.1002G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303965 c.1035G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303995 c.1065C>T synonymous_variant 0.43 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303998 c.1068T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>T synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304502 c.1572G>T synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1304523 c.1593G>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304797 p.Ala623Lys missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304826 c.1896G>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.53 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304904 c.1974G>A synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1305006 p.Glu692Asp missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1305043 c.2113_2115delTCAinsAGT synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1305351 c.2421G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305357 c.2427C>G synonymous_variant 0.57 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305361 c.2431C>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1305381 c.2451G>A synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305399 c.2469A>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1305400 p.His824Asn missense_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1305426 c.2496G>A synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1305429 c.2499G>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1305447 c.2517C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
sigE 1364847 c.435G>C synonymous_variant 0.56 pyrazinamide
sigE 1364859 c.447C>G synonymous_variant 0.57 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.57 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.59 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.71 pyrazinamide Uncertain significance
sigE 1364919 c.507T>C synonymous_variant 0.64 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.59 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.55 pyrazinamide
sigE 1364931 c.519C>G synonymous_variant 0.53 pyrazinamide
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.84 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>T non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>A non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.81 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_635delTCCTTTinsCTCGACTTG non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474708 n.1052_1053insACAAG non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474711 n.1055_1058delGTGT non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475232 n.1575A>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475286 n.1629T>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475297 n.1640C>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036delGinsAA non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1476746 n.3089T>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476755 n.3098G>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
inhA 1673730 c.-472C>G upstream_gene_variant 0.57 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.64 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.64 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.67 ethionamide
isoniazid
inhA 1673772 c.-430C>G upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673778 c.-424C>G upstream_gene_variant 0.55 ethionamide
isoniazid
inhA 1673784 c.-418G>C upstream_gene_variant 0.44 ethionamide
isoniazid
inhA 1673787 c.-415G>C upstream_gene_variant 0.44 ethionamide
isoniazid
fabG1 1673798 p.Ala120Val missense_variant 0.44 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.44 ethionamide
isoniazid
inhA 1673805 c.-397G>C upstream_gene_variant 0.47 ethionamide
isoniazid
inhA 1673808 c.-394A>G upstream_gene_variant 0.47 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.54 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.54 ethionamide
isoniazid
fabG1 1673941 c.502_504delGCCinsTG frameshift_variant&missense_variant 0.67 ethionamide
isoniazid
inhA 1673949 c.-253G>A upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1673953 p.Ser172Ala missense_variant 0.75 ethionamide
isoniazid
inhA 1673958 c.-244G>A upstream_gene_variant 0.75 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.75 ethionamide
isoniazid
inhA 1673967 c.-235G>C upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673973 c.-229G>C upstream_gene_variant 0.63 ethionamide
isoniazid Uncertain significance
fabG1 1674098 p.Val220Ala missense_variant 0.41 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 0.44 ethionamide
isoniazid
fabG1 1674128 p.Ser230Asn missense_variant 0.44 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.41 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.41 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.39 ethionamide
isoniazid
inhA 1674153 c.-49G>C upstream_gene_variant 0.35 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674483 c.282G>C synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.48 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674531 c.330C>T synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.7 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.69 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.64 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.6 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 0.59 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 0.56 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.46 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 0.46 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.44 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 0.38 ethionamide
isoniazid
inhA 1674639 c.438C>G synonymous_variant 0.46 ethionamide
isoniazid
inhA 1674645 c.444C>T synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 0.47 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.47 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 0.47 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 0.59 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCC frameshift_variant&missense_variant 0.61 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 0.59 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674732 c.531C>T synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674742 p.Lys181Pro missense_variant 0.62 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.6 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 0.6 ethionamide
isoniazid
inhA 1674777 c.576C>A synonymous_variant 0.6 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674795 c.594G>C synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.57 ethionamide
isoniazid
inhA 1674804 c.603G>C synonymous_variant 0.58 ethionamide Not assoc w R - Interim
isoniazid
inhA 1674827 p.Glu209Ala missense_variant 0.64 ethionamide
isoniazid
inhA 1674837 c.636C>T synonymous_variant 0.62 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674839 p.Ala213Glu missense_variant 0.6 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.66 ethionamide
isoniazid
inhA 1674847 p.Gln216Lys missense_variant 0.66 ethionamide
isoniazid
inhA 1674864 c.663C>T synonymous_variant 0.7 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.69 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 0.62 ethionamide
isoniazid
rpsA 1833589 c.48A>C synonymous_variant 0.62 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.55 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.55 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.52 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.53 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.53 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.57 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.6 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.64 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.65 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.56 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.57 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.57 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.58 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.58 pyrazinamide
rpsA 1833695 c.154_156delCTCinsTG frameshift_variant&missense_variant 0.59 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>T synonymous_variant 0.62 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.61 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.61 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.61 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.63 pyrazinamide
rpsA 1833745 c.204G>T synonymous_variant 0.72 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 0.71 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 0.73 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.71 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.73 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.71 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.69 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.67 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 0.74 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.79 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.78 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.75 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.75 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.75 pyrazinamide
rpsA 1833859 c.318C>G synonymous_variant 0.76 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.79 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.84 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.81 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.83 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.83 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.81 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.85 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.82 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.83 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.87 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.87 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.9 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.71 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.76 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.74 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.74 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.78 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.79 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
rpsA 1834234 c.693G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834282 c.741C>T synonymous_variant 0.78 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834298 p.Gln253Thr missense_variant 0.76 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.78 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.79 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.88 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.85 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 0.84 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.83 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.82 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.75 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.76 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.76 pyrazinamide Uncertain significance
rpsA 1834600 c.1059G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.83 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.85 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.86 pyrazinamide
rpsA 1834678 c.1137C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.75 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.73 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.66 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.5 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.69 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.71 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.67 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.7 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.67 linezolid
tsnR 1853394 c.-212_-210delCTCinsGCG upstream_gene_variant 0.67 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.71 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.6 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
ndh 2102203 c.840T>G synonymous_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>G synonymous_variant 0.47 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.48 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102245 c.796_798delGTCinsCG frameshift_variant&missense_variant 0.45 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102248 p.Thr265Lys missense_variant 0.44 ethionamide
delamanid
isoniazid
ndh 2102259 p.Ser262Pro missense_variant 0.41 ethionamide
delamanid
isoniazid
ndh 2102266 c.777C>G synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2102842 c.201A>G synonymous_variant 0.44 ethionamide
delamanid
isoniazid
ndh 2102845 c.198A>T synonymous_variant 0.47 ethionamide
delamanid
isoniazid
ndh 2102857 c.186T>C synonymous_variant 0.64 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 0.7 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102866 c.177C>G synonymous_variant 0.75 ethionamide
delamanid
isoniazid
ndh 2102872 c.171A>G synonymous_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2102911 c.132G>C synonymous_variant 0.63 ethionamide
delamanid
isoniazid
ndh 2102929 c.114T>C synonymous_variant 0.48 ethionamide
delamanid
isoniazid
ndh 2102932 c.111C>T synonymous_variant 0.5 ethionamide
delamanid
isoniazid
ndh 2102938 c.105G>C synonymous_variant 0.41 ethionamide
delamanid
isoniazid
katG 2154724 p.Arg463Leu missense_variant 0.77 isoniazid Not assoc w R
katG 2155626 c.486G>C synonymous_variant 0.62 isoniazid
katG 2155632 c.480A>C synonymous_variant 0.7 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.7 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.68 isoniazid Uncertain significance
katG 2155655 p.Lys153Gln missense_variant 0.71 isoniazid Uncertain significance
katG 2155656 c.456G>A synonymous_variant 0.67 isoniazid
katG 2155661 p.Val151Ile missense_variant 0.69 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.75 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.8 isoniazid
katG 2155716 c.396T>C synonymous_variant 0.79 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.77 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.68 isoniazid
katG 2155735 p.Met126Ser missense_variant 0.65 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.66 isoniazid
katG 2155752 c.360C>T synonymous_variant 0.62 isoniazid
katG 2155765 p.His116Phe missense_variant 0.55 isoniazid
PPE35 2170461 p.Gly51Glu missense_variant 0.86 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
pncA 2289047 c.195C>T synonymous_variant 0.8 pyrazinamide Not assoc w R
pncA 2289365 c.-125delC upstream_gene_variant 0.91 pyrazinamide
kasA 2517941 c.-174C>G upstream_gene_variant 0.81 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.76 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 0.7 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.57 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.76 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.84 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.73 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.73 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.71 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.71 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.69 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.71 isoniazid
kasA 2518811 p.Asp233Asn missense_variant 0.77 isoniazid
kasA 2518822 c.708C>G synonymous_variant 0.68 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.66 isoniazid
kasA 2518837 c.723G>A synonymous_variant 0.61 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.56 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.52 isoniazid
kasA 2519044 c.930G>A synonymous_variant 0.44 isoniazid
kasA 2519049 p.Gly312Ala missense_variant 0.44 isoniazid
kasA 2519053 c.939G>C synonymous_variant 0.47 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.56 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.56 isoniazid
kasA 2519072 c.958_960delGCCinsAG frameshift_variant&missense_variant 0.56 isoniazid
kasA 2519077 c.963G>C synonymous_variant 0.65 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.71 isoniazid
kasA 2519105 p.Cys331Val missense_variant 0.71 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 0.69 isoniazid
kasA 2519113 p.Gln333His missense_variant 0.7 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.79 isoniazid
kasA 2519143 c.1029G>C synonymous_variant 0.82 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 0.8 isoniazid
kasA 2519158 c.1044C>G synonymous_variant 0.81 isoniazid
kasA 2519180 c.1066_1068delGTGinsAC frameshift_variant&missense_variant 0.74 isoniazid
kasA 2519194 c.1080G>C synonymous_variant 0.71 isoniazid
kasA 2519195 c.1081_1083delACGinsGA frameshift_variant&missense_variant 0.71 isoniazid
kasA 2519203 c.1089C>T synonymous_variant 0.71 isoniazid
kasA 2519224 c.1110C>A synonymous_variant 0.64 isoniazid
kasA 2519242 c.1128C>G synonymous_variant 0.47 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 0.42 isoniazid
ahpC 2726105 c.-88G>A upstream_gene_variant 0.79 isoniazid Not assoc w R
folC 2746575 p.Met342Leu missense_variant 0.4 para-aminosalicylic_acid
folC 2746576 c.1023C>G synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746599 p.Thr334Ala missense_variant 0.43 para-aminosalicylic_acid
folC 2746600 p.Val333Ala missense_variant 0.46 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 0.5 para-aminosalicylic_acid
folC 2746612 c.987C>A synonymous_variant 0.5 para-aminosalicylic_acid
folC 2746621 c.978C>G synonymous_variant 0.5 para-aminosalicylic_acid
Rv2477c 2782453 c.1590C>T synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782465 c.1578G>A synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782480 c.1563G>A synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782486 c.1557G>A synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.39 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782987 c.1056C>G synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.59 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783047 p.Asp332Glu missense_variant 0.5 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783516 c.526_527delTCinsAG synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.59 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783662 c.381G>A synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2752c 3065025 p.Arg389Lys missense_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065028 c.1164G>C synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065031 c.1161G>C synonymous_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 0.62 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065076 c.1116T>C synonymous_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 0.61 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 0.59 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065091 p.Gln367His missense_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065100 c.1092C>G synonymous_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065109 c.1083A>G synonymous_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065115 c.1077C>G synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067613 c.333G>A synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067646 c.300C>G synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067688 c.258G>C synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067697 c.249C>G synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.63 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3073872 c.598_600delATCinsGG frameshift_variant&missense_variant 0.57 para-aminosalicylic_acid
thyA 3073881 c.591C>T synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3073887 p.Ser195Gly missense_variant 0.55 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3073893 c.579C>A synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.63 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.78 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073971 c.501C>T synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3073993 c.478_479delAGinsTC synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3073995 c.477G>C synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.72 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.36 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
lpqB 3624074 c.837G>C synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624080 p.Arg277Asn missense_variant 0.5 bedaquiline
rifampicin
lpqB 3624087 p.Asp275Gly missense_variant 0.54 bedaquiline
rifampicin
lpqB 3624094 c.817A>C synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624096 p.Ala272Asn missense_variant 0.5 bedaquiline
rifampicin
lpqB 3624098 c.811_813delTTGinsCC frameshift_variant&missense_variant 0.5 bedaquiline
rifampicin Uncertain significance
lpqB 3624116 c.795A>G synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3624122 c.789T>G synonymous_variant 0.41 bedaquiline
rifampicin
lpqB 3624125 c.784_786delTTAinsCG frameshift_variant&missense_variant 0.41 bedaquiline
rifampicin Uncertain significance
lpqB 3624365 c.546T>C synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3624371 c.540T>C synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3624374 c.537G>C synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3624380 p.Lys177Thr missense_variant 0.33 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3624396 p.Ala172Val missense_variant 0.38 bedaquiline
rifampicin
lpqB 3624710 c.201G>C synonymous_variant 0.56 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625060 c.-150G>C upstream_gene_variant 0.38 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 0.5 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625065 p.Met517Leu missense_variant 0.5 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 0.52 bedaquiline
rifampicin
lpqB 3625090 c.-180C>G upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3625093 c.1519_1521delGAGinsAC frameshift_variant&missense_variant 0.5 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625102 c.-192A>G upstream_gene_variant 0.46 bedaquiline
rifampicin
lpqB 3625105 c.-195C>G upstream_gene_variant 0.46 bedaquiline
rifampicin
lpqB 3625111 c.-201G>C upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625117 c.-207T>C upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.52 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 0.55 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625149 p.Val489Ile missense_variant 0.6 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625230 c.-320C>T upstream_gene_variant 0.61 bedaquiline
rifampicin
lpqB 3625231 c.-321G>A upstream_gene_variant 0.61 bedaquiline
rifampicin
lpqB 3625240 c.-330T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
lpqB 3625251 c.-341C>T upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrB 3625252 c.1362G>C synonymous_variant 0.61 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>C upstream_gene_variant 0.61 bedaquiline
rifampicin
lpqB 3625258 c.-348G>A upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.66 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.74 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 0.71 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625342 c.1272C>G synonymous_variant 0.6 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625345 c.-435T>C upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625354 c.-444G>C upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625366 c.-456C>T upstream_gene_variant 0.57 bedaquiline
rifampicin
lpqB 3625369 c.-459G>C upstream_gene_variant 0.53 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.52 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625723 c.-813C>G upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625735 c.879C>A synonymous_variant 0.65 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 0.66 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 0.66 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.66 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3625765 p.Ser283Gln missense_variant 0.64 bedaquiline
rifampicin
lpqB 3625792 c.-882G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625837 c.-927C>T upstream_gene_variant 0.67 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 0.57 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 0.78 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 0.73 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3626792 c.558G>T synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626849 c.-236C>T upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626852 c.-239G>A upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrA 3627247 p.Ile35Val missense_variant 0.67 bedaquiline
rifampicin
mtrB 3627251 c.-638G>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627263 c.-650C>A upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3627272 c.-659G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3627305 c.43_45delGCTinsCC frameshift_variant&synonymous_variant 0.71 bedaquiline
rifampicin
mtrB 3627308 c.-695C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3627325 c.-712T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.65 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.45 bedaquiline
rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.82 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.89 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 0.88 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.87 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.86 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.87 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 0.87 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.89 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.89 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>T synonymous_variant 0.7 rifampicin
rpoA 3877842 c.666A>G synonymous_variant 0.67 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.74 rifampicin
rpoA 3877881 c.627G>C synonymous_variant 0.76 rifampicin
rpoA 3877884 c.624G>C synonymous_variant 0.74 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 0.75 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.87 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.73 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.71 rifampicin Uncertain significance
rpoA 3877989 c.519A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoA 3878157 c.351C>G synonymous_variant 0.55 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>C synonymous_variant 0.65 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.67 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 0.78 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.48 rifampicin
rpoA 3878358 c.150C>G synonymous_variant 0.48 rifampicin
rpoA 3878361 c.147G>A synonymous_variant 0.48 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.46 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.48 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.48 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3878394 c.114G>C synonymous_variant 0.44 rifampicin
rpoA 3878400 c.108T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878409 c.99C>G synonymous_variant 0.38 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.39 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.3 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.32 rifampicin
rpoA 3878842 c.-335G>C upstream_gene_variant 0.38 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.55 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.63 rifampicin Uncertain significance
rpoA 3878886 c.-379G>A upstream_gene_variant 0.65 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 0.63 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 0.67 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.67 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.66 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.67 rifampicin
rpoA 3878929 c.-422G>C upstream_gene_variant 0.62 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.65 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.55 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 0.45 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.43 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 0.4 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.35 rifampicin
rpoA 3879040 c.-535_-533delGTGinsAAC upstream_gene_variant 0.46 rifampicin
rpoA 3879049 c.-542A>C upstream_gene_variant 0.46 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.56 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 0.55 rifampicin
rpoA 3879078 c.-571A>C upstream_gene_variant 0.56 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.59 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.66 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.67 rifampicin
rpoA 3879121 c.-616_-614delCTTinsACC upstream_gene_variant 0.65 rifampicin
rpoA 3879124 c.-618_-617delTGinsGC upstream_gene_variant 0.67 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.69 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.67 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.66 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.48 rifampicin
clpC1 4038499 p.Ser736Gly missense_variant 0.6 pyrazinamide
clpC1 4038519 p.Arg729Lys missense_variant 0.7 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.77 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.79 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.8 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.83 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.83 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.84 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.82 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.78 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.76 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.77 pyrazinamide
clpC1 4038683 c.2020_2022delTCTinsAGC synonymous_variant 0.77 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.74 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.74 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.72 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>T synonymous_variant 0.74 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.77 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.88 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.88 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.86 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.79 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.59 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.56 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.6 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.62 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.65 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.67 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.7 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.76 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 0.8 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039016 c.1689C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039019 c.1686G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.91 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039073 c.1632C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.77 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.95 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.9 pyrazinamide
clpC1 4039193 c.1512C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.87 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 0.72 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.71 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4039328 c.1377A>T synonymous_variant 0.71 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.69 pyrazinamide
clpC1 4039347 p.Arg453Lys missense_variant 0.64 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.67 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.62 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.61 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.62 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.64 pyrazinamide
clpC1 4039445 c.1260C>T synonymous_variant 0.68 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>T synonymous_variant 0.76 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.77 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.77 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.78 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039501 c.1204C>T synonymous_variant 0.72 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 0.84 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039688 c.1017G>A synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4039694 c.1011G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.78 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.71 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.45 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.52 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.46 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.46 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.59 pyrazinamide
clpC1 4039901 c.804C>T synonymous_variant 0.6 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.6 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.65 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.66 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.6 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.57 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.6 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.62 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.63 pyrazinamide
clpC1 4040069 c.636G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.59 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.58 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4040138 c.567G>C synonymous_variant 0.52 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.5 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.47 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.44 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.3 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.43 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.64 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 0.61 pyrazinamide
clpC1 4040257 p.Ala150Ser missense_variant 0.61 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040279 c.426C>G synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.61 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.54 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040315 c.390G>A synonymous_variant 0.53 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.44 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.39 pyrazinamide
clpC1 4040333 c.372G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040336 c.369G>T synonymous_variant 0.42 pyrazinamide
clpC1 4040342 c.363C>T synonymous_variant 0.43 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.43 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.41 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.6 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.6 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.52 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.68 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.73 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.76 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.76 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>T synonymous_variant 0.77 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.71 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.7 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040558 c.147G>C synonymous_variant 0.61 pyrazinamide
clpC1 4040561 c.144A>T synonymous_variant 0.59 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.7 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.7 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.7 pyrazinamide
clpC1 4040693 c.12A>T synonymous_variant 0.81 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.69 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.37 pyrazinamide
panD 4044204 c.78G>C synonymous_variant 0.39 pyrazinamide
panD 4044225 c.57C>T synonymous_variant 0.37 pyrazinamide
panD 4044230 c.52delGinsAGT frameshift_variant&missense_variant 0.35 pyrazinamide Uncertain significance
panD 4044237 c.45G>C synonymous_variant 0.35 pyrazinamide
panD 4044240 c.42G>C synonymous_variant 0.33 pyrazinamide
panD 4044246 c.36C>A synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
glpK 4138517 c.1239A>G synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138532 c.1224G>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138577 c.1177_1179delCTGinsGC frameshift_variant&missense_variant 0.71 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138583 c.1173G>C synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138616 c.1140G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>G synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139143 c.613T>C synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139150 c.606G>C synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>C synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>T synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139189 c.567G>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139408 c.348T>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139417 c.339A>G synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139420 c.336T>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139435 c.321C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139441 c.315A>G synonymous_variant 0.44 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
embC 4239512 c.-351G>C upstream_gene_variant 0.5 ethambutol Uncertain significance
embC 4239526 c.-337_-336delGGinsAC upstream_gene_variant 0.56 ethambutol
embC 4239530 c.-333C>G upstream_gene_variant 0.53 ethambutol
embC 4239533 c.-330T>C upstream_gene_variant 0.56 ethambutol
embC 4239539 c.-324G>C upstream_gene_variant 0.56 ethambutol
embC 4239540 c.-323T>C upstream_gene_variant 0.56 ethambutol
embC 4239545 c.-318G>A upstream_gene_variant 0.5 ethambutol Uncertain significance
embC 4239546 c.-317_-315delCCGinsTC upstream_gene_variant 0.5 ethambutol
embC 4239569 c.-294A>G upstream_gene_variant 0.41 ethambutol Uncertain significance
embC 4239579 c.-284A>C upstream_gene_variant 0.4 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.59 ethambutol Not assoc w R - Interim
embC 4240736 p.Ser292Ala missense_variant 0.67 ethambutol
embC 4240756 c.894G>C synonymous_variant 0.78 ethambutol
embC 4240768 c.906G>T synonymous_variant 0.8 ethambutol
embC 4240771 c.909G>C synonymous_variant 0.8 ethambutol
embC 4240777 c.915G>A synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embC 4240779 p.His306Arg missense_variant 0.78 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.81 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.8 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.78 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.72 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.71 ethambutol
embC 4240855 c.993G>C synonymous_variant 0.48 ethambutol
embC 4240858 c.996G>C synonymous_variant 0.48 ethambutol
embC 4240865 c.1003_1005delGCTinsTG frameshift_variant&missense_variant 0.43 ethambutol
embC 4240870 p.His336Gln missense_variant 0.48 ethambutol Uncertain significance
embC 4241024 p.Val388Phe missense_variant 0.33 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.4 ethambutol
embC 4241047 c.1185C>T synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4241050 c.1188T>G synonymous_variant 0.53 ethambutol
embC 4241071 c.1209C>G synonymous_variant 0.62 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.65 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.62 ethambutol
embC 4241109 p.Ala416Gly missense_variant 0.62 ethambutol
embC 4241116 c.1254C>G synonymous_variant 0.68 ethambutol
embC 4241125 c.1263G>C synonymous_variant 0.61 ethambutol
embC 4241137 c.1275G>C synonymous_variant 0.52 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4241147 p.Cys429Val missense_variant 0.38 ethambutol
embC 4242075 p.Arg738Gln missense_variant 1.0 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247401 c.888T>C synonymous_variant 0.38 ethambutol
embB 4247404 c.891G>A synonymous_variant 0.41 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.43 ethambutol
embB 4247416 c.903C>A synonymous_variant 0.44 ethambutol
embB 4247426 p.Gly305Gln missense_variant 0.46 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.56 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.56 ethambutol Not assoc w R - Interim
embB 4247464 c.951C>G synonymous_variant 0.66 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.67 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.65 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.57 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.48 ethambutol
embB 4248025 c.1512A>G synonymous_variant 0.4 ethambutol
embB 4248035 c.1522_1524delGTTinsAC frameshift_variant&missense_variant 0.35 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.35 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.35 ethambutol
embB 4248052 c.1539G>C synonymous_variant 0.36 ethambutol Not assoc w R - Interim
embB 4248055 c.1542G>C synonymous_variant 0.4 ethambutol
embB 4248063 p.Ala517Glu missense_variant 0.35 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.33 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.46 ethambutol
embB 4248202 c.1689T>C synonymous_variant 0.46 ethambutol
embB 4248206 c.1693_1695delAGCinsGG frameshift_variant&missense_variant 0.46 ethambutol
embB 4248211 c.1698G>T synonymous_variant 0.45 ethambutol
embB 4248214 c.1701C>G synonymous_variant 0.45 ethambutol
embB 4248223 c.1710G>C synonymous_variant 0.51 ethambutol
embB 4248226 c.1713G>C synonymous_variant 0.51 ethambutol
embB 4248242 p.Val577Ile missense_variant 0.68 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.71 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.71 ethambutol
embB 4248259 p.Met582Ile missense_variant 0.69 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.5 ethambutol
embB 4248290 c.1777_1779delGTGinsAC frameshift_variant&missense_variant 0.43 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.4 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 0.47 ethambutol
aftB 4267567 p.Leu424Met missense_variant 0.5 ethambutol
aftB 4267571 c.1266T>C synonymous_variant 0.53 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 0.53 ethambutol
aftB 4267586 c.1251C>G synonymous_variant 0.64 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 0.64 ethambutol Not assoc w R - Interim
aftB 4267622 c.1213_1215delTCGinsAC frameshift_variant&missense_variant 0.68 ethambutol Uncertain significance
aftB 4267625 c.1210_1212delTATinsGC frameshift_variant&missense_variant 0.68 ethambutol Uncertain significance
aftB 4267646 p.Asp397Pro missense_variant 0.59 ethambutol
aftB 4267655 c.1182C>G synonymous_variant 0.62 ethambutol
aftB 4267658 c.1179G>C synonymous_variant 0.59 ethambutol
aftB 4267664 c.1173C>T synonymous_variant 0.59 ethambutol
aftB 4267667 c.1170A>C synonymous_variant 0.59 ethambutol
aftB 4268386 c.451T>C synonymous_variant 0.45 ethambutol
aftB 4268393 c.444G>C synonymous_variant 0.45 ethambutol Not assoc w R - Interim
aftB 4268396 c.441T>C synonymous_variant 0.43 ethambutol
aftB 4268402 c.433_435delTTGinsCC frameshift_variant&missense_variant 0.38 ethambutol Uncertain significance
aftB 4268405 c.432G>T synonymous_variant 0.37 ethambutol
aftB 4268415 p.Ser141Asn missense_variant 0.36 ethambutol
aftB 4268422 c.415C>T synonymous_variant 0.39 ethambutol
aftB 4268423 c.414C>G synonymous_variant 0.41 ethambutol
aftB 4268444 c.393C>G synonymous_variant 0.34 ethambutol Not assoc w R - Interim
aftB 4268450 c.387A>C synonymous_variant 0.4 ethambutol
aftB 4268462 c.375T>C synonymous_variant 0.3 ethambutol
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4407588 c.615A>G synonymous_variant 0.75 streptomycin Not assoc w R