TB-Profiler result

Run: SRR9971114
Summary

Run ID: SRR9971114

Sample name:

Date: 2024-04-15T10:48:23.372796

Number of reads: 5639572

Percentage reads mapped: 34.67

Median coverage: 133.0

Strain: lineage2.2.1

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 1.0
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 1.0
lineage2.2 East-Asian (Beijing) RD105;RD207 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance Mutation from literature
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
amikacin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.61 kanamycin Assoc w R
amikacin Assoc w R
capreomycin Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 660 c.660G>C synonymous_variant 0.18 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.18 isoniazid
dnaA 666 c.666C>G synonymous_variant 0.19 isoniazid
dnaA 675 c.675C>G synonymous_variant 0.19 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.18 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>T synonymous_variant 0.18 isoniazid
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 0.18 isoniazid Uncertain significance
dnaA 687 c.687C>T synonymous_variant 0.18 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.24 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.27 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.29 isoniazid
dnaA 714 c.714C>T synonymous_variant 0.26 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.29 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.37 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>T synonymous_variant 0.33 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 0.33 isoniazid Uncertain significance
dnaA 763 p.Lys255Arg missense_variant 0.35 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.42 isoniazid
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.42 isoniazid Uncertain significance
dnaA 801 c.801G>T synonymous_variant 0.39 isoniazid
dnaA 804 c.804G>C synonymous_variant 0.37 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.42 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 0.41 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.38 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.38 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.35 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.36 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.36 isoniazid Not assoc w R - Interim
dnaA 877 c.877T>C synonymous_variant 0.33 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.3 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.3 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.29 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>C synonymous_variant 0.22 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.22 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.18 isoniazid
gyrA 6652 c.-650C>T upstream_gene_variant 0.16 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>T upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.32 levofloxacin Uncertain significance
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6754 c.-548C>T upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.35 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6808 c.1569C>G synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.33 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6838 c.-464C>T upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6872 c.-430T>C upstream_gene_variant 0.15 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7024 c.-278G>C upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>T upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.2 levofloxacin
moxifloxacin
gyrB 7054 c.1815C>T synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7123 c.-179C>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 7126 c.1887G>C synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7132 c.-170T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7189 c.-113C>T upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 7234 c.-68C>A upstream_gene_variant 0.15 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7442 c.141G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.18 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7763 c.462T>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Ser missense_variant 0.22 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8817 p.Ser506Ala missense_variant 0.21 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8829 c.1528_1530delTTGinsCC frameshift_variant&missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 8837 c.1536C>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8840 c.1539C>T synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8846 c.1545C>T synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Lys missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 8978 c.1677C>T synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8993 c.1692C>T synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.29 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9002 c.1701C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9018 p.Gln573Lys missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9047 c.1746C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.16 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.18 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>A synonymous_variant 0.17 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 0.18 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.18 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 0.18 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.18 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.21 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.19 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.19 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.18 ethionamide
isoniazid Not assoc w R - Interim
mshA 575821 c.474G>C synonymous_variant 0.2 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.19 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.18 ethionamide
isoniazid
mshA 575907 p.Ala187Val missense_variant 0.91 ethionamide Not assoc w R
isoniazid Not assoc w R
mshA 576108 p.Ala254Gly missense_variant 0.35 ethionamide
isoniazid
ccsA 620625 p.Ile245Met missense_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Uncertain significance
ccsA 620694 c.804C>G synonymous_variant 0.15 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.16 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 620764 p.Ala292Ser missense_variant 0.16 capreomycin
amikacin
kanamycin
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
nusG 734445 c.192C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
nusG 734452 c.199_201delGAAinsCG frameshift_variant&missense_variant 0.16 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734497 c.244_246delGTGinsAC frameshift_variant&missense_variant 0.22 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
nusG 734535 c.282C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
nusG 734807 p.Tyr185Phe missense_variant 0.14 rifampicin
rpoB 760079 c.273G>A synonymous_variant 0.15 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760110 c.304_306delTCTinsAGC synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760118 c.312T>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.27 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.21 rifampicin Uncertain significance
rpoB 760276 p.Lys157Met missense_variant 0.23 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760340 c.534G>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.21 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.22 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.32 rifampicin Uncertain significance
rpoB 760382 c.576G>C synonymous_variant 0.27 rifampicin
rpoB 760388 c.582C>T synonymous_variant 0.28 rifampicin
rpoB 760400 c.594G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.3 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.35 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>A synonymous_variant 0.33 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.38 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.44 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760541 c.735G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.32 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.32 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.32 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.34 rifampicin
rpoB 760588 p.Thr261Ile missense_variant 0.33 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.38 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.38 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.4 rifampicin
rpoB 760608 c.802C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760668 c.862_864delACGinsGC frameshift_variant&missense_variant 0.24 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.18 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.2 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.27 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.35 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.37 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.31 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760865 c.1059C>G synonymous_variant 0.33 rifampicin
rpoB 760886 p.Glu360Asp missense_variant 0.38 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.41 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760928 c.1122G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.34 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.38 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760979 c.1173G>A synonymous_variant 0.22 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.24 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.32 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761048 c.1242C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>T synonymous_variant 0.31 rifampicin
rpoB 761060 c.1254C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.38 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.38 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761178 c.1372_1374delTCAinsAC frameshift_variant&missense_variant 0.31 rifampicin
rpoB 761186 p.Glu460Asp missense_variant 0.36 rifampicin Uncertain significance
rpoB 761189 c.1383T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.18 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761231 c.1425C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>T synonymous_variant 0.31 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761276 c.1470G>C synonymous_variant 0.31 rifampicin
rpoB 761297 c.1491C>T synonymous_variant 0.26 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761339 c.1533C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.23 rifampicin
rpoB 761346 p.Val514Ser missense_variant 0.18 rifampicin
rpoB 761354 c.1548C>A synonymous_variant 0.19 rifampicin
rpoB 761357 c.1551G>T synonymous_variant 0.2 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.26 rifampicin
rpoB 761366 c.1560C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761373 p.Val523His missense_variant 0.19 rifampicin
rpoB 761393 c.1587G>A synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761537 c.1731C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.19 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761627 c.1821C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>A synonymous_variant 0.17 rifampicin
rpoB 761636 c.1830G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761657 c.1851C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.2 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.17 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.18 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.17 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.18 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.18 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.18 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.17 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.18 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.2 rifampicin
rpoB 761936 c.2130C>T synonymous_variant 0.16 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>A synonymous_variant 0.19 rifampicin
rpoB 761955 p.Ile717Val missense_variant 0.19 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762098 c.2292C>G synonymous_variant 0.15 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.57 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.36 rifampicin
rpoB 762125 p.Glu773Asp missense_variant 0.16 rifampicin
rpoB 762128 c.2322G>C synonymous_variant 0.16 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.58 rifampicin
rpoB 762134 c.2328C>A synonymous_variant 0.39 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.6 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.61 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 0.18 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>G synonymous_variant 0.47 rifampicin
rpoB 762177 p.Arg791Gly missense_variant 0.16 rifampicin
rpoB 762181 p.Asp792Ala missense_variant 0.16 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762189 p.Ile795Val missense_variant 0.17 rifampicin
rpoB 762194 c.2388G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.18 rifampicin
rpoB 762227 c.2421G>A synonymous_variant 0.32 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.32 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.34 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 0.17 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.22 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762323 c.2517C>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.32 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.32 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.31 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 0.21 rifampicin
rpoB 762353 c.2547C>T synonymous_variant 0.18 rifampicin
rpoB 762356 p.Glu850Asp missense_variant 0.18 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.34 rifampicin
rpoB 762368 p.Glu854Asp missense_variant 0.22 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.35 rifampicin
rpoC 762374 c.-996G>T upstream_gene_variant 0.26 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.23 rifampicin
rpoC 762383 c.-987C>G upstream_gene_variant 0.26 rifampicin
rpoC 762392 c.-978G>C upstream_gene_variant 0.27 rifampicin
rpoC 762395 c.-975G>T upstream_gene_variant 0.31 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.39 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762410 c.2604T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.27 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.27 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.27 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.26 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.26 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.23 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.16 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762866 c.3060C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.28 rifampicin Uncertain significance
rpoB 762894 c.3088C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.46 rifampicin Not assoc w R
rpoB 763031 c.3225T>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763145 c.3339G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763157 c.3351G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.19 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.18 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.19 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.2 rifampicin
rpoC 763450 c.81G>A synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>A synonymous_variant 0.2 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.2 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.32 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.29 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.25 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.25 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763609 c.240C>T synonymous_variant 0.19 rifampicin
rpoC 763618 c.249C>G synonymous_variant 0.32 rifampicin
rpoC 763622 c.253_255delGCCinsTG frameshift_variant&missense_variant 0.3 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763642 c.273G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763686 p.Tyr106Phe missense_variant 0.23 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.25 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.41 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.41 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.47 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.15 rifampicin
rpoC 763732 c.363C>A synonymous_variant 0.27 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.31 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.36 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.3 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763774 c.405G>C synonymous_variant 0.19 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.18 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.28 rifampicin
rpoC 763796 c.427_429delATGinsCC frameshift_variant&missense_variant 0.16 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.19 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.23 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.22 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.22 rifampicin
rpoC 763870 c.501C>T synonymous_variant 0.15 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.23 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.22 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.22 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.22 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.22 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763933 c.564C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.25 rifampicin Uncertain significance
rpoC 763947 p.Ala193Val missense_variant 0.25 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763972 c.603C>T synonymous_variant 0.19 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.21 rifampicin
rpoC 763991 c.622_624delATCinsCT frameshift_variant&missense_variant 0.19 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.2 rifampicin
rpoC 763999 c.630C>T synonymous_variant 0.19 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.19 rifampicin
rpoC 764003 p.Ala212Ser missense_variant 0.19 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.21 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.21 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.2 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.21 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.22 rifampicin
rpoC 764054 c.685C>T synonymous_variant 0.2 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.17 rifampicin
rpoC 764110 c.741C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764147 c.778_780delTCGinsGC frameshift_variant&missense_variant 0.19 rifampicin
rpoC 764150 c.781_783delATCinsGG frameshift_variant&missense_variant 0.19 rifampicin
rpoC 764165 p.Glu266Gln missense_variant 0.18 rifampicin
rpoC 764176 c.807C>T synonymous_variant 0.15 rifampicin
rpoC 764182 c.813C>T synonymous_variant 0.17 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 0.21 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.21 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.22 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.22 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.22 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.23 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.24 rifampicin
rpoC 764311 c.942C>G synonymous_variant 0.19 rifampicin
rpoC 764317 c.948C>G synonymous_variant 0.21 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.2 rifampicin
rpoC 764338 p.Glu323Asp missense_variant 0.31 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.23 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.52 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.57 rifampicin
rpoC 764419 c.1050C>G synonymous_variant 0.24 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.58 rifampicin
rpoC 764440 c.1071G>C synonymous_variant 0.22 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.22 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.28 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764491 c.1122G>C synonymous_variant 0.21 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764498 p.Ser377Ala missense_variant 0.18 rifampicin
rpoC 764507 p.Ala380Ser missense_variant 0.19 rifampicin
rpoC 764510 c.1141C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.4 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 0.29 rifampicin
rpoC 764573 c.1204_1206delCTTinsAG frameshift_variant&missense_variant 0.29 rifampicin
rpoC 764578 c.1209C>G synonymous_variant 0.29 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.28 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.29 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.35 rifampicin
rpoC 764605 c.1236G>T synonymous_variant 0.37 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>T synonymous_variant 0.21 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 0.3 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764705 p.Leu446* stop_gained 0.23 rifampicin
rpoC 764713 c.1344G>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764737 c.1368G>C synonymous_variant 0.34 rifampicin
rpoC 764746 c.1377G>C synonymous_variant 0.43 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.32 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764785 c.1416C>G synonymous_variant 0.28 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.27 rifampicin
rpoC 764801 c.1433_1434insTG frameshift_variant 0.28 rifampicin
rpoC 764804 c.1436_1437delAG frameshift_variant 0.25 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.31 rifampicin Not assoc w R
rpoC 764810 c.1441_1443delCCCinsGG frameshift_variant&missense_variant 0.22 rifampicin
rpoC 764813 p.Gln482Val missense_variant 0.25 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764843 p.Ala492Thr missense_variant 0.25 rifampicin
rpoC 764854 c.1485G>C synonymous_variant 0.22 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.25 rifampicin
rpoC 764884 c.1515C>T synonymous_variant 0.22 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.3 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.3 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.18 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765403 c.2034G>C synonymous_variant 0.21 rifampicin
rpoC 765405 p.Leu679His missense_variant 0.21 rifampicin Uncertain significance
rpoC 765409 c.2040T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765421 c.2052C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765449 c.2080_2082delGCCinsTG frameshift_variant&missense_variant 0.24 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765469 c.2100G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>G synonymous_variant 0.27 rifampicin
rpoC 765480 p.Tyr704Phe missense_variant 0.3 rifampicin Uncertain significance
rpoC 765499 c.2130C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.22 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.21 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.16 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.15 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.16 rifampicin
rpoC 765861 p.Phe831Tyr missense_variant 0.17 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.31 rifampicin Uncertain significance
rpoC 765895 c.2526G>A synonymous_variant 0.2 rifampicin
rpoC 765907 c.2538G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.28 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>G synonymous_variant 0.2 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 766513 c.3144C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 766534 c.3165C>G synonymous_variant 0.17 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.18 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.19 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.16 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 0.16 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.15 rifampicin
rpoC 766837 c.3468G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766867 c.3498C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766909 c.3540G>C synonymous_variant 0.15 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.16 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.16 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.17 rifampicin
rpoC 766931 c.3562_3564delGCAinsTG frameshift_variant&stop_gained 0.2 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>T synonymous_variant 0.28 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 767080 c.3711G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 767107 c.3738C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Ser missense_variant 0.36 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.28 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.29 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Ser missense_variant 0.16 rifampicin Uncertain significance
rpoC 767281 c.3912C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 775904 c.2577G>A synonymous_variant 0.18 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.23 clofazimine
bedaquiline
mmpL5 775970 c.2511G>C synonymous_variant 0.15 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.17 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776182 p.Asp767Asn missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781572 c.13_15delCAGinsAC frameshift_variant&missense_variant 0.21 streptomycin Uncertain significance
rpsL 781586 c.27C>T synonymous_variant 0.21 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.23 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.24 streptomycin
rpsL 781616 c.57C>G synonymous_variant 0.2 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.25 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.32 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.31 streptomycin
rpsL 781658 c.99A>C synonymous_variant 0.27 streptomycin Not assoc w R - Interim
rpsL 781670 c.111G>C synonymous_variant 0.28 streptomycin
rpsL 781706 c.147T>C synonymous_variant 0.24 streptomycin
rpsL 781715 c.156T>G synonymous_variant 0.22 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.18 streptomycin
rpsL 781725 p.Lys56Arg missense_variant 0.16 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.26 streptomycin
rpsL 781738 p.Gln60Pro missense_variant 0.17 streptomycin
rpsL 781742 c.183C>G synonymous_variant 0.2 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.33 streptomycin
rpsL 781754 c.195G>T synonymous_variant 0.2 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.37 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.19 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.23 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.41 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.35 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.15 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.49 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.5 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.49 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.5 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.16 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.45 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 0.16 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.53 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.52 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.35 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.51 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.41 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.17 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.48 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.47 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.43 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.24 streptomycin
rplC 800612 c.-197A>G upstream_gene_variant 0.17 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.3 linezolid
rplC 800639 c.-170C>T upstream_gene_variant 0.17 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.33 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.33 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.35 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 0.22 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.18 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.3 linezolid
rplC 800703 c.-106_-104delTTGinsCC upstream_gene_variant 0.35 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.29 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.28 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.28 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.34 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.23 linezolid
rplC 800856 c.48A>G synonymous_variant 0.16 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.16 linezolid
rplC 800880 c.72A>C synonymous_variant 0.15 linezolid
rplC 800892 c.84G>C synonymous_variant 0.17 linezolid
rplC 800904 c.96G>C synonymous_variant 0.21 linezolid
rplC 800916 c.108A>G synonymous_variant 0.22 linezolid
rplC 800931 c.123G>C synonymous_variant 0.2 linezolid
rplC 800937 c.129A>G synonymous_variant 0.19 linezolid
rplC 800946 c.138T>C synonymous_variant 0.19 linezolid
rplC 800949 c.141T>C synonymous_variant 0.19 linezolid
rplC 800964 c.156G>C synonymous_variant 0.19 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1304580 c.1650T>C synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.16 clofazimine
pretomanid
delamanid
sigE 1364691 c.279T>C synonymous_variant 0.17 pyrazinamide
sigE 1364694 c.282G>C synonymous_variant 0.17 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 0.18 pyrazinamide
sigE 1364709 c.297T>G synonymous_variant 0.2 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.22 pyrazinamide
sigE 1364718 c.306C>T synonymous_variant 0.22 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.23 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 0.22 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.23 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 0.24 pyrazinamide
sigE 1364751 c.339C>G synonymous_variant 0.26 pyrazinamide
sigE 1364757 c.345G>A synonymous_variant 0.27 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.28 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 0.28 pyrazinamide
sigE 1364781 c.369G>A synonymous_variant 0.28 pyrazinamide
sigE 1364782 c.370_372delGTCinsTG frameshift_variant&missense_variant 0.28 pyrazinamide Uncertain significance
sigE 1364790 c.378T>C synonymous_variant 0.28 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.33 pyrazinamide
sigE 1364814 c.402C>T synonymous_variant 0.31 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.31 pyrazinamide
sigE 1364823 c.411C>T synonymous_variant 0.26 pyrazinamide
sigE 1364838 c.426C>T synonymous_variant 0.27 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.26 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.25 pyrazinamide
sigE 1364856 c.444C>T synonymous_variant 0.2 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 0.18 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.22 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.2 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
sigE 1364883 c.471G>A synonymous_variant 0.18 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.19 pyrazinamide Uncertain significance
sigE 1364950 c.538_540delGCAinsTC frameshift_variant&missense_variant 0.15 pyrazinamide Uncertain significance
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
atpE 1461113 c.69C>T synonymous_variant 0.2 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.27 bedaquiline
atpE 1461146 c.102G>T synonymous_variant 0.25 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.3 bedaquiline
atpE 1461161 c.117C>G synonymous_variant 0.27 bedaquiline
atpE 1461164 c.120C>T synonymous_variant 0.27 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 0.32 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.31 bedaquiline
atpE 1461179 c.135G>T synonymous_variant 0.27 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.3 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.3 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.29 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.26 bedaquiline
atpE 1461230 c.186G>T synonymous_variant 0.19 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.21 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.16 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.16 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.27 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.21 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.42 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472043 n.198T>A non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472050 n.205G>C non_coding_transcript_exon_variant 0.18 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.16 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.33 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472434 n.589_590insC non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.22 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472438 n.594delC non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>A non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.22 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472469 n.625_626insATC non_coding_transcript_exon_variant 0.22 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472473 n.629_631delCGA non_coding_transcript_exon_variant 0.22 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472583 n.738T>C non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472701 n.856T>A non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.16 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.15 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.15 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.58 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443_1444delCTinsGTTCG non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.16 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473294 n.1449_1455delAGGGAGCinsGGGAGT non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473707 n.50T>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473722 n.65G>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1473750 n.93C>A non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1473782 n.125A>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1473788 n.131A>C non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1473797 n.140G>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1473839 n.182G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473845 n.188G>C non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524_525insT non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474381 n.724T>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756A>C non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474415 n.759_781delCACACGCGCATACGCGCGTGTGA non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053_1058delTGGTGTinsGTAAGTG non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.75 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.15 capreomycin
linezolid
rrl 1475061 n.1404_1408delCAAGGinsAAGA non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475068 n.1411A>G non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475078 n.1421T>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475174 n.1517C>G non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1475176 n.1519G>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1475220 n.1563G>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.73 capreomycin
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475604 n.1950_1951delAT non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475608 n.1951T>G non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475634 n.1977_1981delGGATCinsTGGA non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475752 n.2095C>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.71 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.51 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.51 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.51 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.6 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.64 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.57 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.63 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.64 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.4 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rpsA 1833547 c.6G>A synonymous_variant 0.24 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.35 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.35 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.34 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.3 pyrazinamide
rpsA 1833616 c.75A>T synonymous_variant 0.34 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.39 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.33 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.42 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.48 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.44 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.35 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.4 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833700 c.159C>T synonymous_variant 0.35 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.4 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 0.29 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.41 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.34 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.38 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.32 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.4 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.42 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.41 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.38 pyrazinamide
rpsA 1833823 c.282G>A synonymous_variant 0.26 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.19 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.47 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.43 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.49 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.5 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.53 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.46 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.34 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.46 pyrazinamide
rpsA 1833893 p.Ala118Lys missense_variant 0.16 pyrazinamide
rpsA 1833896 p.Leu119Ile missense_variant 0.16 pyrazinamide
rpsA 1833905 p.Lys122Glu missense_variant 0.18 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.17 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.18 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.33 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 0.28 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.28 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.28 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.61 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.26 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.33 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.63 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.3 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.3 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.28 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.31 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.31 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.62 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.59 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.59 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.33 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.57 pyrazinamide
rpsA 1834033 c.492C>T synonymous_variant 0.28 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.25 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.26 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834073 p.Lys178Arg missense_variant 0.19 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.22 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.15 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.21 pyrazinamide
rpsA 1834228 c.687C>A synonymous_variant 0.33 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.38 pyrazinamide
rpsA 1834234 c.693G>T synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834243 c.702G>C synonymous_variant 0.2 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.32 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.37 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.59 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>T synonymous_variant 0.46 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.44 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.17 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.53 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834307 c.766_768delGACinsCG frameshift_variant&missense_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834318 c.777C>G synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834327 c.786G>T synonymous_variant 0.55 pyrazinamide
rpsA 1834330 c.789C>G synonymous_variant 0.16 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.44 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.37 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834429 c.888C>T synonymous_variant 0.36 pyrazinamide
rpsA 1834438 c.897C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
rpsA 1834451 c.910T>C synonymous_variant 0.51 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.51 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.54 pyrazinamide
rpsA 1834513 c.972C>T synonymous_variant 0.41 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834520 c.979_981delGCCinsTG frameshift_variant&missense_variant 0.44 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.46 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.3 pyrazinamide
rpsA 1834558 c.1017C>T synonymous_variant 0.32 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.34 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.28 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.32 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834645 c.1104C>T synonymous_variant 0.21 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.33 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.33 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834700 p.Gln387Ala missense_variant 0.24 pyrazinamide
rpsA 1834705 c.1164C>G synonymous_variant 0.24 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 0.25 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.34 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.34 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.31 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.3 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.2 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.28 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.28 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.26 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.17 linezolid
tsnR 1853372 c.-234A>G upstream_gene_variant 0.17 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.16 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.16 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.16 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.16 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.17 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
kasA 2517917 c.-198G>C upstream_gene_variant 0.23 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.38 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.16 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.3 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.29 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.19 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.26 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 0.15 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.19 isoniazid
kasA 2518795 c.681C>T synonymous_variant 0.17 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.15 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.17 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.15 isoniazid
Rv2477c 2783059 c.984T>C synonymous_variant 0.14 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783086 c.957C>T synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>A synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783098 c.945C>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783105 p.Val313Thr missense_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783119 c.924G>A synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783137 c.906C>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783157 p.Ala296Thr missense_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 p.Ala295Val missense_variant 0.19 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783173 c.870C>G synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783182 c.861C>T synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>T synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783192 p.Ser284Asn missense_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783203 c.840C>G synonymous_variant 0.13 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783584 c.457_459delGCCinsCG frameshift_variant&synonymous_variant 0.14 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783883 c.160T>C synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>A synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783897 p.Arg49Lys missense_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783901 c.142T>C synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783902 c.141C>G synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783908 c.135G>C synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
thyA 3073959 c.513T>C synonymous_variant 0.17 para-aminosalicylic_acid
thyA 3074013 c.459C>T synonymous_variant 0.17 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.16 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.16 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0 pyrazinamide Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625711 c.903C>T synonymous_variant 0.18 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.18 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.18 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.18 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 0.18 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626562 p.Pro18Ser missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3626704 c.-91C>T upstream_gene_variant 0.25 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.26 bedaquiline
rifampicin
mtrB 3626717 c.-104C>T upstream_gene_variant 0.26 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.3 bedaquiline
rifampicin
mtrA 3626741 c.609C>G synonymous_variant 0.3 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626756 c.594C>G synonymous_variant 0.32 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626759 c.591T>C synonymous_variant 0.32 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626762 c.588G>C synonymous_variant 0.31 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626786 c.564A>G synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.36 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626804 c.546A>G synonymous_variant 0.38 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 0.31 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 0.21 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.18 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.15 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.16 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.16 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.17 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.15 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.26 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 0.26 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 0.24 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627110 c.-497G>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.15 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>G upstream_gene_variant 0.16 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.22 bedaquiline
rifampicin
mtrA 3627133 p.Ala73Ser missense_variant 0.15 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3627143 c.-530G>C upstream_gene_variant 0.16 bedaquiline
rifampicin
mtrB 3627149 c.-536G>A upstream_gene_variant 0.16 bedaquiline
rifampicin
rpoA 3877542 c.966C>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877545 c.963G>C synonymous_variant 0.19 rifampicin
rpoA 3877554 c.954G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsAC frameshift_variant&missense_variant 0.25 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.38 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877665 c.843C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877677 c.831G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.32 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 0.27 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.3 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.31 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.26 rifampicin
rpoA 3877758 c.750G>C synonymous_variant 0.27 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.36 rifampicin
rpoA 3877797 c.711G>A synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>A synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>A synonymous_variant 0.3 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3877929 c.577_579delATCinsGG frameshift_variant&missense_variant 0.28 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.39 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877977 p.Lys177Asn missense_variant 0.26 rifampicin Uncertain significance
rpoA 3877989 c.519A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>C synonymous_variant 0.33 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.28 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.42 rifampicin
rpoA 3878028 c.480G>T synonymous_variant 0.35 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.43 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.43 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 0.34 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.45 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.44 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.34 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.46 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 0.31 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.17 rifampicin
rpoA 3878102 p.Val136Ile missense_variant 0.32 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.47 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.52 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.42 rifampicin
rpoA 3878142 p.Gly122Asp missense_variant 0.4 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.42 rifampicin Uncertain significance
rpoA 3878202 c.306G>C synonymous_variant 0.42 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3878250 c.258C>T synonymous_variant 0.34 rifampicin
rpoA 3878259 c.249G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.34 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3878343 c.165C>G synonymous_variant 0.17 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 0.18 rifampicin
clpC1 4038602 c.2103G>C synonymous_variant 0.17 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.19 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.17 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.17 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.17 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.17 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.17 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.18 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.2 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.22 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.21 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.22 pyrazinamide
clpC1 4038737 c.1968C>T synonymous_variant 0.16 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.37 pyrazinamide
clpC1 4038749 c.1956C>A synonymous_variant 0.21 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.44 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.45 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.4 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.48 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.32 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.31 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.56 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.39 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.55 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.39 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.57 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.54 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.52 pyrazinamide
clpC1 4038923 c.1782A>T synonymous_variant 0.51 pyrazinamide
clpC1 4038928 c.1777C>A synonymous_variant 0.48 pyrazinamide
clpC1 4038929 c.1776G>A synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4038932 c.1773G>C synonymous_variant 0.47 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.54 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.51 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.51 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4038977 c.1728G>A synonymous_variant 0.43 pyrazinamide
clpC1 4038986 c.1719C>T synonymous_variant 0.44 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.57 pyrazinamide
clpC1 4039031 c.1674T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.15 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039077 p.Lys543Arg missense_variant 0.34 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.49 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.4 pyrazinamide
clpC1 4039094 c.1611C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4039097 c.1608G>T synonymous_variant 0.51 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.52 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.51 pyrazinamide
clpC1 4039124 c.1581C>A synonymous_variant 0.35 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.17 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.49 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.34 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.28 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.45 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.3 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.23 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.24 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.25 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.4 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039262 c.1443C>T synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4039265 c.1440C>T synonymous_variant 0.21 pyrazinamide
clpC1 4039271 c.1434G>A synonymous_variant 0.21 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 0.17 pyrazinamide
clpC1 4039286 c.1417_1419delCTTinsTA frameshift_variant&synonymous_variant 0.18 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 0.18 pyrazinamide
clpC1 4039316 p.Glu463Asp missense_variant 0.16 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4039337 p.Thr456Gln missense_variant 0.26 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4039360 p.Ser449Arg missense_variant 0.18 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.46 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.45 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.46 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.41 pyrazinamide Uncertain significance
clpC1 4039427 c.1278G>A synonymous_variant 0.4 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.48 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4039517 c.1188C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.32 pyrazinamide
clpC1 4039528 c.1177C>A synonymous_variant 0.29 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 0.28 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039565 c.1140G>T synonymous_variant 0.25 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.32 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 0.22 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.41 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.3 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.25 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039619 c.1086G>A synonymous_variant 0.24 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.39 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.39 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.24 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.15 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.51 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.26 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.35 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.31 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.43 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.41 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.41 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4039769 c.936C>G synonymous_variant 0.36 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.45 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.41 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.27 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4039913 c.792C>T synonymous_variant 0.27 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039937 c.768G>A synonymous_variant 0.27 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.24 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.37 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.38 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039964 c.739_741delCTCinsTG frameshift_variant&synonymous_variant 0.25 pyrazinamide
clpC1 4039975 p.Asp244Asn missense_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.26 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4040009 c.696C>G synonymous_variant 0.29 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 0.33 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.4 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.41 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.39 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.37 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.36 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.36 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.35 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>T synonymous_variant 0.31 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.32 pyrazinamide
clpC1 4040174 c.531C>T synonymous_variant 0.3 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.14 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 0.15 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.17 pyrazinamide
clpC1 4040309 c.396C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040333 c.372G>C synonymous_variant 0.21 pyrazinamide
clpC1 4040342 c.363C>A synonymous_variant 0.19 pyrazinamide
clpC1 4040348 c.357G>T synonymous_variant 0.19 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.22 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.21 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.21 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.23 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.23 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.23 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.16 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.28 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.28 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.35 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.36 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.36 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.35 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.35 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.34 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>T synonymous_variant 0.35 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.41 pyrazinamide
clpC1 4040540 c.165G>T synonymous_variant 0.37 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040558 c.147G>C synonymous_variant 0.28 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.36 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.28 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.28 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.26 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCG frameshift_variant&missense_variant 0.26 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.25 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.26 pyrazinamide
glpK 4138550 c.1206C>T synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138556 c.1200G>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138559 c.1197G>A synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138562 c.1194G>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138579 c.1177C>T synonymous_variant 0.23 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138601 c.1155G>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>T synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138616 c.1140G>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>A synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 0.28 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138643 c.1113A>G synonymous_variant 0.31 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138664 c.1092G>C synonymous_variant 0.26 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.28 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138694 p.Pro354Glu missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138706 c.1050C>G synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138711 c.1045C>T synonymous_variant 0.15 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138718 c.1038T>C synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.15 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138726 p.Ala344Ser missense_variant 0.15 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240765 c.903C>A synonymous_variant 0.15 ethambutol
embC 4240779 p.His306Arg missense_variant 0.14 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.29 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.29 ethambutol
embC 4240826 p.Ala322Ser missense_variant 0.17 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.26 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4243460 c.228C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247491 c.978G>C synonymous_variant 0.19 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.18 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 0.18 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.18 ethambutol
embB 4247536 c.1023C>G synonymous_variant 0.17 ethambutol
aftB 4267647 p.Asp397Gly missense_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407620 p.Tyr195His missense_variant 1.0 streptomycin Not assoc w R
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Not assoc w R