TB-Profiler result

Run: ERR2446566

Summary

Run ID: ERR2446566

Sample name:

Date: 2024-03-26T20:22:25.985011

Number of reads: 215299

Percentage reads mapped: 65.67

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other


Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.94
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ofloxacin
levofloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.820_822delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrB 6738 p.Thr500Asn missense_variant 0.94 moxifloxacin Uncertain significance Mutation from literature
levofloxacin Uncertain significance Mutation from literature
fbiC 1303750 c.820_822delTTAinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.95 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 540 c.540C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 541 p.Ala181Thr missense_variant 1.0 isoniazid
dnaA 552 c.552G>C synonymous_variant 1.0 isoniazid
dnaA 555 c.555C>T synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 576 c.576G>C synonymous_variant 1.0 isoniazid
dnaA 579 c.579C>T synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>C synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 1.0 isoniazid
dnaA 600 c.600T>C synonymous_variant 1.0 isoniazid
dnaA 633 c.633T>G synonymous_variant 1.0 isoniazid
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 663 c.663A>C synonymous_variant 1.0 isoniazid
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 673 p.Ala225Thr missense_variant 1.0 isoniazid Uncertain significance
dnaA 678 c.678A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 690 c.690G>C synonymous_variant 1.0 isoniazid
dnaA 699 c.699G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 948 c.948C>T synonymous_variant 1.0 isoniazid
dnaA 955 c.955A>C synonymous_variant 1.0 isoniazid
dnaA 963 c.963C>A synonymous_variant 1.0 isoniazid
dnaA 966 c.966T>C synonymous_variant 1.0 isoniazid
dnaA 969 c.969G>A synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>C synonymous_variant 1.0 isoniazid
dnaA 976 c.976C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
gyrB 6170 p.His311Val missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6202 c.963C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6203 c.964_965delAGinsTC synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGC synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6229 c.990G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.88 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6310 c.-992G>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6326 c.-976_-975delAGinsTC upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6329 c.1090_1092delGAAinsCG frameshift_variant&missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>T synonymous_variant 0.95 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6724 c.-578G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7460 c.159C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7577 c.276C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7614 c.313C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7640 c.339G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7670 c.369A>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7671 p.Pro124Ala missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCT frameshift_variant&missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7706 c.405C>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7745 c.444G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7748 c.447A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7752 p.Asp151Asn missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7758 c.457_459delATCinsGT frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7778 c.477G>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7799 c.498A>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7808 c.507G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7850 c.549C>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7853 c.552C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>T synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8769 p.His490Tyr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8885 c.1584C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9064 p.Ser588Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9212 c.1911G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9281 c.1980C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9329 c.2028C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCT frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9398 c.2097T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9407 c.2106C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491307 c.525C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491447 p.Val222Ala missense_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491453 p.Gly224Ala missense_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491502 c.720G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491520 c.738C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491536 c.754C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491546 p.Thr255Ser missense_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575714 p.Tyr123Asn missense_variant 1.0 ethionamide
isoniazid
mshA 575725 c.378C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575780 c.433_435delCCGinsGC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575788 c.441C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 1.0 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575812 c.465C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575818 c.471G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.92 ethionamide
isoniazid
hadA 731732 c.-198G>C upstream_gene_variant 0.8 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.91 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 0.91 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.87 isoniazid
hadA 731831 c.-99G>A upstream_gene_variant 0.73 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.73 isoniazid
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.92 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.96 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.96 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.97 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.98 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.98 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.98 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734505 c.252G>T synonymous_variant 0.98 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>T synonymous_variant 1.0 rifampicin
nusG 734595 c.342C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734596 c.343_345delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734614 c.361_363delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734832 c.579C>G synonymous_variant 1.0 rifampicin
nusG 734841 c.588G>C synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734859 c.606G>C synonymous_variant 1.0 rifampicin
nusG 734863 c.610_612delACGinsTC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734886 c.633A>G synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734904 c.651G>T synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734922 c.669C>A synonymous_variant 1.0 rifampicin
nusG 734928 c.675A>G synonymous_variant 1.0 rifampicin
nusG 734934 c.681G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.85 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.86 rifampicin
rpoB 760155 p.Lys117Arg missense_variant 0.88 rifampicin
rpoB 760175 c.369C>T synonymous_variant 0.93 rifampicin
rpoB 760178 c.372G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 1.0 rifampicin
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.9 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.87 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 0.87 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.83 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.8 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.78 rifampicin
rpoB 760354 p.Glu183Ala missense_variant 0.71 rifampicin
rpoB 760357 p.Thr184Asn missense_variant 0.71 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.53 rifampicin Uncertain significance
rpoB 760439 c.633C>T synonymous_variant 0.6 rifampicin
rpoB 760449 p.Thr215Leu missense_variant 0.6 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.75 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760494 c.688_690delGTGinsAC frameshift_variant&missense_variant 0.82 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.92 rifampicin Uncertain significance
rpoB 760580 c.774G>A synonymous_variant 0.92 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.9 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.91 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760668 p.Thr288Ala missense_variant 1.0 rifampicin Uncertain significance
rpoB 760671 c.865_867delCTGinsTA frameshift_variant&stop_gained 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 1.0 rifampicin
rpoB 760718 c.912C>G synonymous_variant 1.0 rifampicin
rpoB 760916 c.1110C>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761003 c.1197C>G synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761012 c.1206C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.94 rifampicin
rpoB 761189 c.1383T>G synonymous_variant 0.94 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761201 c.1395G>A synonymous_variant 0.91 rifampicin
rpoB 761261 c.1455G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 1.0 rifampicin
rpoB 761300 c.1494G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761373 p.Val523His missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.92 rifampicin
rpoB 761482 p.Ala559Gly missense_variant 0.9 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.95 rifampicin
rpoB 761502 c.1696_1698delCCCinsTT frameshift_variant&missense_variant 0.95 rifampicin
rpoB 761508 c.1702_1704delTCTinsGC frameshift_variant&missense_variant 0.95 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 1.0 rifampicin
rpoB 761534 c.1728G>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761627 c.1821C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 1.0 rifampicin
rpoB 761712 p.Val636Ile missense_variant 1.0 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 1.0 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761728 p.Ser641Thr missense_variant 1.0 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761760 p.Ile652Val missense_variant 1.0 rifampicin
rpoB 761765 c.1959T>G synonymous_variant 0.96 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761789 c.1983G>C synonymous_variant 1.0 rifampicin
rpoB 761791 p.Arg662Gln missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761814 p.Ala670Asn missense_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 1.0 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 1.0 rifampicin
rpoB 761897 c.2091C>G synonymous_variant 1.0 rifampicin
rpoB 761903 c.2097T>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762006 c.2200_2202delCGCinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762024 p.Val740Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762275 c.2469C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>A synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762490 p.Val895Ala missense_variant 1.0 rifampicin
rpoC 762512 c.-858C>G upstream_gene_variant 0.9 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoB 762560 c.2754A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762563 c.-807G>T upstream_gene_variant 1.0 rifampicin
rpoC 762575 c.-795C>T upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762911 c.-459C>T upstream_gene_variant 1.0 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 1.0 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoB 763203 p.Ser1133Ala missense_variant 1.0 rifampicin Uncertain significance
rpoB 763207 p.Ser1134Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763247 c.-123G>A upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 1.0 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 1.0 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 0.98 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>A synonymous_variant 0.97 rifampicin
rpoC 763618 c.249C>T synonymous_variant 0.97 rifampicin
rpoC 763657 c.288G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>A synonymous_variant 0.97 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763921 c.552G>C synonymous_variant 0.91 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763939 c.570G>A synonymous_variant 0.92 rifampicin
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.95 rifampicin
rpoC 764085 p.Asn239Thr missense_variant 0.95 rifampicin Uncertain significance
rpoC 764087 p.Leu240Val missense_variant 0.95 rifampicin Uncertain significance
rpoC 764098 c.729A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764104 c.735C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764107 c.738C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.97 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 0.93 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 0.93 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.91 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Ile missense_variant 0.9 rifampicin
rpoC 764213 p.Arg282Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 764227 c.858G>C synonymous_variant 1.0 rifampicin
rpoC 764254 c.885G>A synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.97 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.97 rifampicin
rpoC 764353 c.984G>C synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 1.0 rifampicin
rpoC 764428 c.1059G>T synonymous_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764482 c.1113G>A synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 1.0 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 1.0 rifampicin
rpoC 764573 c.1204_1206delCTTinsTG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764656 c.1287C>G synonymous_variant 0.96 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>C synonymous_variant 0.96 rifampicin
rpoC 764680 c.1311G>A synonymous_variant 0.97 rifampicin
rpoC 764689 c.1320G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 0.98 rifampicin
rpoC 764746 c.1377G>A synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>C synonymous_variant 1.0 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764846 p.Glu493Gln missense_variant 0.87 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.89 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.82 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.85 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.85 rifampicin Uncertain significance
rpoC 764932 c.1563C>G synonymous_variant 0.89 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.91 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.94 rifampicin
rpoC 764959 c.1590G>A synonymous_variant 0.97 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.98 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>T synonymous_variant 0.98 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.97 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765115 c.1746G>C synonymous_variant 1.0 rifampicin
rpoC 765118 c.1749C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>C synonymous_variant 1.0 rifampicin
rpoC 765358 p.Met663Ile missense_variant 0.93 rifampicin Uncertain significance
rpoC 765382 c.2013G>C synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765404 p.Leu679Ala missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765422 p.Asn685Asp missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765453 p.Ala695Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765544 c.2175C>G synonymous_variant 1.0 rifampicin
rpoC 765547 c.2178C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>G synonymous_variant 1.0 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765611 p.His748Ala missense_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765635 c.2266_2268delGTCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765640 c.2271A>G synonymous_variant 1.0 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765662 c.2293_2295delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765669 p.His767Arg missense_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765718 p.Asp783Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765724 c.2355C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 1.0 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765937 c.2568T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Gly missense_variant 1.0 rifampicin
rpoC 766048 c.2679C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766061 p.Val898Ile missense_variant 0.95 rifampicin
rpoC 766069 p.Glu900Asp missense_variant 0.94 rifampicin
rpoC 766070 c.2701C>T synonymous_variant 0.93 rifampicin Not assoc w R
rpoC 766078 c.2710delC frameshift_variant 0.85 rifampicin
rpoC 766085 c.2716delCinsGG frameshift_variant&missense_variant 0.75 rifampicin
rpoC 766093 c.2724C>A synonymous_variant 0.75 rifampicin
rpoC 766094 p.Thr909Ser missense_variant 0.75 rifampicin
rpoC 766106 p.Asp913Asn missense_variant 0.64 rifampicin
rpoC 766113 p.Tyr915Phe missense_variant 0.62 rifampicin
rpoC 766115 p.Ile916Val missense_variant 0.62 rifampicin Uncertain significance
rpoC 766120 c.2751A>G synonymous_variant 0.62 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.55 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766280 c.2911_2913delAGCinsGA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 1.0 rifampicin
rpoC 766291 c.2922G>C synonymous_variant 1.0 rifampicin
rpoC 766297 c.2928G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766300 c.2931C>G synonymous_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.96 rifampicin
rpoC 766321 c.2952C>A synonymous_variant 0.97 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766351 c.2982C>G synonymous_variant 0.98 rifampicin
rpoC 766357 c.2988C>T synonymous_variant 0.98 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.98 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.97 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.97 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.98 rifampicin
rpoC 766435 c.3066G>A synonymous_variant 0.98 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766468 c.3099G>A synonymous_variant 0.98 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.97 rifampicin
rpoC 766517 p.Thr1050Ala missense_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.97 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 1.0 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766547 p.Arg1060Lys missense_variant 1.0 rifampicin
rpoC 766564 c.3195C>G synonymous_variant 1.0 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766610 p.Ser1081Pro missense_variant 0.95 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.95 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.95 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.95 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.94 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.94 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.94 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 0.94 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.94 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 0.94 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 0.94 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.9 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>G synonymous_variant 1.0 rifampicin
rpoC 766753 c.3384C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Asn missense_variant 1.0 rifampicin
rpoC 766787 p.Glu1140Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 1.0 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>G synonymous_variant 1.0 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766931 c.3562_3564delGCAinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766935 p.Glu1189Ala missense_variant 1.0 rifampicin
rpoC 766942 c.3573C>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766961 p.Gly1198Leu missense_variant 1.0 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767041 c.3672G>C synonymous_variant 1.0 rifampicin
rpoC 767044 c.3675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767110 c.3741T>C synonymous_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767182 c.3813G>C synonymous_variant 0.98 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.98 rifampicin
rpoC 767197 c.3828G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>T synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767266 c.3897G>C synonymous_variant 1.0 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
rpoC 767302 c.3933C>G synonymous_variant 1.0 rifampicin
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781586 c.27C>T synonymous_variant 0.87 streptomycin
rpsL 781592 c.33T>C synonymous_variant 0.87 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.87 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.87 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.87 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.87 streptomycin
rpsL 781616 c.57C>G synonymous_variant 0.87 streptomycin
rpsL 781622 c.63C>T synonymous_variant 0.88 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.88 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.88 streptomycin
rpsL 781652 c.93T>G synonymous_variant 0.88 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.88 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.88 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.91 streptomycin
rpsL 781685 c.126G>C synonymous_variant 0.91 streptomycin
rpsL 781703 c.144G>A synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.94 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>G synonymous_variant 0.94 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.94 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.94 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.94 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.94 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.94 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.94 streptomycin
rpsL 781742 c.183C>G synonymous_variant 0.94 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.94 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.94 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.94 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.95 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.95 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.95 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.96 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.97 streptomycin
rpsL 781814 c.255C>G synonymous_variant 0.97 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.97 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.95 streptomycin
rpsL 781853 c.294C>T synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>A synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781910 c.351C>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>G synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.98 streptomycin Uncertain significance
rplC 800645 c.-164C>G upstream_gene_variant 0.93 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.92 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.93 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.95 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.95 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.93 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 0.92 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801150 c.342G>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>A synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801176 p.Phe123Tyr missense_variant 1.0 linezolid
rplC 801205 p.Arg133Ala missense_variant 1.0 linezolid
rplC 801210 c.402T>C synonymous_variant 1.0 linezolid
rplC 801220 p.Ser138Gly missense_variant 1.0 linezolid
fbiC 1303488 c.558G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303554 c.624G>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303768 p.Ser280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303791 c.861C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303800 c.870G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305197 p.Ala756Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305207 c.2277C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305213 c.2283C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305216 c.2286C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305252 c.2322G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305264 c.2334C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305318 c.2388C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305339 c.2409C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305381 c.2451G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305399 c.2469A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364920 p.Glu170Gln missense_variant 1.0 pyrazinamide
sigE 1364926 p.Asn172Asp missense_variant 1.0 pyrazinamide
sigE 1364952 c.540A>G synonymous_variant 1.0 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 1.0 pyrazinamide
sigE 1364960 p.Gly183Asp missense_variant 1.0 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>A synonymous_variant 1.0 pyrazinamide
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364992 p.Pro194Ala missense_variant 1.0 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
atpE 1461128 c.84C>T synonymous_variant 0.92 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.93 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.92 bedaquiline
atpE 1461153 p.Ser37Ala missense_variant 0.92 bedaquiline Uncertain significance
atpE 1461158 c.114T>A synonymous_variant 0.92 bedaquiline
atpE 1461159 c.115_117delGTCinsAT frameshift_variant&missense_variant 0.92 bedaquiline
atpE 1461167 c.123G>C synonymous_variant 0.92 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.92 bedaquiline
atpE 1461179 c.135G>T synonymous_variant 0.92 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.92 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.92 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.91 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472292 n.447A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472302 n.457_458insT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472310 n.465_466insG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838_839insTA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473111 n.1266A>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473752 n.95G>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473810 n.153C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474026 n.369C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474106 n.449A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474107 n.450T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474108 n.451C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474109 n.452A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474110 n.453A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474284 n.629dupC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474290 n.633T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474292 n.636_644delTCCTCTCCG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474414 n.757C>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474415 n.758C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474420 n.763C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474421 n.764G>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474423 n.767_768delCA non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474427 n.770A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474428 n.771C>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474430 n.773C>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474716 n.1059_1060insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475375 n.1718G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475378 n.1721A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475379 n.1722G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475395 n.1740_1741delGC non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475400 n.1743C>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475402 n.1745_1746insATA non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475408 n.1752delT non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475433 n.1776A>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475614 n.1957A>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476108 n.2451T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476717 n.3060C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
inhA 1674295 p.Gln32Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674312 c.111G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674313 p.Leu38Cys missense_variant 1.0 ethionamide
isoniazid
inhA 1674443 p.Ala81Val missense_variant 0.9 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 0.93 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674483 c.282G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674489 c.288G>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674514 p.Ile105Val missense_variant 0.97 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.95 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.98 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 0.98 ethionamide
isoniazid
inhA 1674597 c.396G>A synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 0.97 ethionamide
isoniazid
inhA 1674619 c.418_420delCCCinsGG frameshift_variant&missense_variant 0.97 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674636 c.435C>G synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674651 c.450C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.97 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833547 c.6G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.98 pyrazinamide
rpsA 1833770 p.Asn77His missense_variant 0.98 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.98 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833797 p.Val86Ile missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1833802 c.261A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833814 c.273C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.99 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834042 c.501G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834172 p.Ile211Val missense_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834183 c.642T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834499 c.958C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834522 c.981C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834527 p.Arg329His missense_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834573 c.1032G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834603 p.Glu354Asp missense_variant 0.98 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.97 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834650 p.Thr370Ser missense_variant 0.97 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.97 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834751 c.1210_1212delCTTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834756 p.Glu405Asp missense_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
kasA 2517926 c.-189G>A upstream_gene_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517992 c.-123C>G upstream_gene_variant 1.0 isoniazid
kasA 2517995 c.-120C>G upstream_gene_variant 1.0 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 0.9 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.73 isoniazid
kasA 2518300 c.186T>A synonymous_variant 0.91 isoniazid
kasA 2518312 c.198T>C synonymous_variant 0.91 isoniazid
kasA 2518492 c.378C>T synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518564 c.450C>G synonymous_variant 1.0 isoniazid
kasA 2518570 c.456G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 1.0 isoniazid
kasA 2518582 c.468G>T synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518594 c.480C>T synonymous_variant 1.0 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518630 c.516G>C synonymous_variant 1.0 isoniazid
kasA 2518636 c.522C>T synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.97 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.97 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.97 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.97 isoniazid
kasA 2518678 c.564C>A synonymous_variant 0.97 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.97 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.97 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.97 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.97 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.97 isoniazid
kasA 2518727 c.613C>T synonymous_variant 0.94 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.93 isoniazid
kasA 2518739 p.Ala209Thr missense_variant 0.93 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.92 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.88 isoniazid
kasA 2518759 c.645C>G synonymous_variant 0.87 isoniazid
kasA 2518771 c.657C>T synonymous_variant 0.75 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.92 isoniazid
ahpC 2726604 p.Val138Ile missense_variant 0.93 isoniazid
ahpC 2726612 c.420C>G synonymous_variant 0.94 isoniazid
ahpC 2726618 c.426C>T synonymous_variant 0.94 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.95 isoniazid
ahpC 2726642 c.450C>G synonymous_variant 0.95 isoniazid
ahpC 2726645 c.453C>A synonymous_variant 0.95 isoniazid
ahpC 2726648 c.456T>A synonymous_variant 0.95 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 0.91 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.91 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.95 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.95 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.92 isoniazid
folC 2746966 c.633G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746975 c.624T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746978 c.621C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747007 p.Ser198Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747032 c.567A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747035 c.562_564delAACinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747038 c.559_561delATCinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747098 c.501C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747122 c.477G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747128 p.Ala157Gly missense_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782462 c.1581C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782465 c.1578G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782494 p.Asp517Asn missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782513 c.1530G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783084 p.Val320Gln missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783098 c.945C>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783126 p.Phe306Tyr missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 c.885A>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783182 c.861C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783506 c.537C>T synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783516 c.526_527delTCinsAG synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783545 c.498C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783557 c.486T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783963 p.Ser27Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783967 c.76T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783974 c.69C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783986 c.57G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783989 c.54G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784001 c.42G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784004 c.39G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784010 c.33C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784047 c.-5G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996554 c.-185A>C upstream_gene_variant 0.96 capreomycin
Rv2681 2996560 c.-179G>C upstream_gene_variant 0.96 capreomycin
Rv2681 2996563 c.-176A>C upstream_gene_variant 0.96 capreomycin
Rv2680 2996576 p.Ser158Ala missense_variant 0.97 capreomycin
Rv2681 2996590 c.-149C>G upstream_gene_variant 0.97 capreomycin
Rv2680 2996592 p.Ala163Gly missense_variant 0.97 capreomycin
Rv2681 2996605 c.-134G>A upstream_gene_variant 0.97 capreomycin
Rv2681 2996608 c.-131A>G upstream_gene_variant 0.94 capreomycin
Rv2681 2996611 c.-128G>C upstream_gene_variant 0.97 capreomycin
Rv2681 2996632 c.-107C>A upstream_gene_variant 0.97 capreomycin
Rv2680 2996638 p.Asp178Glu missense_variant 0.97 capreomycin
Rv2680 2996645 p.Ala181Ser missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2996665 c.-74C>T upstream_gene_variant 1.0 capreomycin
Rv2680 2996668 p.Asp188Glu missense_variant 1.0 capreomycin
Rv2752c 3065972 p.Ile74Val missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065988 p.Glu68Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066000 p.Met64Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066024 c.168T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066036 c.156C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066042 c.150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 c.142T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066071 c.121T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066078 c.114C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066081 c.111G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066096 c.96G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067304 c.642A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067309 p.Ile213Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067328 c.618G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067364 c.582C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067382 c.564C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067423 c.523C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067770 p.Gly59Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 1.0 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3073887 p.Ser195Gly missense_variant 0.94 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073926 c.546G>A synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073965 c.507C>T synonymous_variant 0.77 para-aminosalicylic_acid
lpqB 3624365 c.546T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624386 c.525C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624396 p.Ala172Val missense_variant 0.96 bedaquiline
rifampicin
lpqB 3624404 c.507G>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624410 c.501C>T synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624422 c.487_489delACGinsGC frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin Uncertain significance
lpqB 3624425 p.Glu162Ala missense_variant 0.95 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624452 c.459T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624455 c.456G>A synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624464 c.447A>G synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3624467 c.444C>G synonymous_variant 0.87 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 0.87 bedaquiline
rifampicin
lpqB 3624482 c.429T>G synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624485 p.Asp142Glu missense_variant 0.82 bedaquiline
rifampicin
lpqB 3625609 c.-699C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625612 c.-702G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625623 p.Thr331Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625627 p.Asp329Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625637 p.Ala326Asp missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625639 c.-729C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625648 c.964_966delTATinsCC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625695 c.-785C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625702 c.-792C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625761 p.Gln285Glu missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625765 c.-855C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625819 c.795G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625879 c.-969G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625882 c.732G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625885 c.-975G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625891 c.723G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626696 c.-83T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3626731 p.Lys207Gln missense_variant 0.94 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626735 c.-122C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3626741 c.609C>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 0.93 bedaquiline
rifampicin
mtrA 3626942 c.406_408delGTAinsAC frameshift_variant&missense_variant 0.93 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626962 p.Met130Leu missense_variant 0.93 bedaquiline
rifampicin
mtrB 3626966 c.-353C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626999 c.-386G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627002 c.-389G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627016 c.-403C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627053 c.297C>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627056 c.294C>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627068 c.282T>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627125 c.-512C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627131 p.Ala73Lys missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627134 c.-521C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627149 c.-536G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>A upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627197 c.-584T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
rpoA 3877534 p.Val325Ala missense_variant 1.0 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877548 c.960C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877553 p.Glu319Gln missense_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877596 c.912G>C synonymous_variant 1.0 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 1.0 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>T synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877689 c.819C>G synonymous_variant 1.0 rifampicin
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877788 c.720G>A synonymous_variant 1.0 rifampicin
rpoA 3877803 c.705G>C synonymous_variant 1.0 rifampicin
rpoA 3877815 c.693C>G synonymous_variant 1.0 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877827 c.681C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877842 c.666A>G synonymous_variant 1.0 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 0.93 rifampicin
rpoA 3877893 c.615C>G synonymous_variant 0.94 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.89 rifampicin
rpoA 3877929 c.577_579delATCinsGG frameshift_variant&missense_variant 0.89 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.94 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.93 rifampicin Uncertain significance
rpoA 3877995 c.513G>A synonymous_variant 0.8 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878093 p.Val139Ile missense_variant 0.95 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.95 rifampicin
rpoA 3878100 c.408C>G synonymous_variant 0.96 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.96 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.96 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.97 rifampicin
rpoA 3878121 c.387C>T synonymous_variant 0.97 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.98 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.98 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878202 c.306G>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878232 c.276G>C synonymous_variant 1.0 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>T synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>T synonymous_variant 1.0 rifampicin
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.97 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.97 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878394 c.114G>T synonymous_variant 0.97 rifampicin
rpoA 3878400 c.108T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 0.97 rifampicin
rpoA 3878421 c.87A>C synonymous_variant 0.94 rifampicin
rpoA 3878430 c.78G>C synonymous_variant 0.93 rifampicin
rpoA 3878433 c.75G>C synonymous_variant 0.92 rifampicin
rpoA 3878716 c.-209C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878725 c.-220_-218delCTAinsTG upstream_gene_variant 1.0 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878758 c.-251G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878773 c.-268_-266delAGCinsGT upstream_gene_variant 1.0 rifampicin
rpoA 3878782 c.-275G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878785 c.-278T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878796 c.-289G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878806 c.-299C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878830 c.-325_-323delCTGinsAC upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878843 c.-337_-336delCGinsAA upstream_gene_variant 1.0 rifampicin
rpoA 3878845 c.-338G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878873 c.-366G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878889 c.-382A>G upstream_gene_variant 0.96 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 0.96 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.96 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.96 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.96 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.96 rifampicin
rpoA 3878947 c.-440G>T upstream_gene_variant 0.92 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 0.92 rifampicin
rpoA 3878962 c.-455G>T upstream_gene_variant 0.91 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-572A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879097 c.-590C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.97 rifampicin
rpoA 3879124 c.-618_-617delTGinsGC upstream_gene_variant 0.97 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.97 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.94 rifampicin
rpoA 3879178 c.-671T>G upstream_gene_variant 0.88 rifampicin
rpoA 3879190 c.-683C>A upstream_gene_variant 0.88 rifampicin
rpoA 3879199 c.-692C>T upstream_gene_variant 0.83 rifampicin
ddn 3986616 c.-228_-227delAGinsGC upstream_gene_variant 0.91 delamanid
pretomanid
ddn 3986622 c.-222C>T upstream_gene_variant 0.91 delamanid
pretomanid
clpC1 4038317 c.2388G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038325 p.Val794Ile missense_variant 1.0 pyrazinamide
clpC1 4038329 c.2376G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038335 c.2370C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.93 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.93 pyrazinamide
clpC1 4038533 p.Arg724Lys missense_variant 0.93 pyrazinamide
clpC1 4038538 p.Thr723Ser missense_variant 0.94 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038602 c.2103G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038621 p.Gln695Leu missense_variant 0.92 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.92 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.92 pyrazinamide
clpC1 4038644 p.Glu687Asp missense_variant 0.93 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.93 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.93 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.93 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038674 c.2031C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.88 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4038692 c.2011_2013delTCCinsGG frameshift_variant&missense_variant 0.83 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.8 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 0.92 pyrazinamide
clpC1 4038722 c.1983G>C synonymous_variant 0.92 pyrazinamide
clpC1 4038725 p.Thr660Cys missense_variant 0.92 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038782 c.1923G>A synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038790 c.1915C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038809 p.Gln632Ser missense_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.97 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.95 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.95 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.92 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039001 c.1702_1704delAACinsGG frameshift_variant&missense_variant 0.95 pyrazinamide
clpC1 4039004 c.1701C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039031 c.1674T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 1.0 pyrazinamide
clpC1