TB-Profiler result

Run: SRR10315567
Summary

Run ID: SRR10315567

Sample name:

Date: 2024-04-15T22:06:56.498652

Number of reads: 4809757

Percentage reads mapped: 33.64

Median coverage: 120.0

Strain: lineage2.2.1

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.99
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 0.99
lineage2.2 East-Asian (Beijing) RD105;RD207 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.346_348delCACinsGG Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.766_768delGCTinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.21 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491548 c.766_768delGCTinsCC frameshift_variant&missense_variant 0.2 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 0.19 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance Mutation from literature
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance Mutation from literature
amikacin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.67 amikacin Assoc w R
kanamycin Assoc w R
capreomycin Assoc w R
katG 2155764 c.346_348delCACinsGG frameshift_variant&missense_variant 0.2 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 840 c.840G>A synonymous_variant 0.15 isoniazid
gyrB 6793 c.1554T>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.17 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6811 c.1572C>T synonymous_variant 0.19 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7123 c.-179C>G upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.15 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7433 c.132G>A synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.17 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.19 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 8549 c.1248C>T synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>T synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>A synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.16 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.16 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8946 c.1645T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9293 c.1992G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9323 c.2022C>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCC frameshift_variant&missense_variant 0.22 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9407 c.2106C>T synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491490 c.708C>T synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fgd1 491536 c.754C>T synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>T synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fgd1 491562 c.780C>T synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fgd1 491571 c.789C>T synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>T synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.15 ethionamide
isoniazid
mshA 575725 c.378C>G synonymous_variant 0.27 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.28 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.29 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>A synonymous_variant 0.29 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 0.3 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.29 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 0.3 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.28 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.3 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.31 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.31 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.31 ethionamide
isoniazid Not assoc w R - Interim
mshA 575821 c.474G>C synonymous_variant 0.27 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.28 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.2 ethionamide
isoniazid
mshA 575907 p.Ala187Val missense_variant 0.9 ethionamide Not assoc w R
isoniazid Not assoc w R
ccsA 620625 p.Ile245Met missense_variant 0.97 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Uncertain significance
ccsA 620661 c.771C>G synonymous_variant 0.16 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 0.18 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.16 capreomycin
amikacin
kanamycin
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
nusG 734454 c.201A>G synonymous_variant 0.17 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.2 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760061 p.Tyr85* stop_gained 0.16 rifampicin
rpoB 760070 c.264T>C synonymous_variant 0.18 rifampicin
rpoB 760082 c.276C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 0.25 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.25 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.28 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.34 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 0.3 rifampicin
rpoB 760139 c.333A>T synonymous_variant 0.3 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.29 rifampicin
rpoB 760178 c.372G>A synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760206 p.Ile134Val missense_variant 0.17 rifampicin
rpoB 760212 p.Asn136Tyr missense_variant 0.17 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760275 p.Lys157Arg missense_variant 0.16 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.41 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.4 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.42 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.41 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.41 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.45 rifampicin Uncertain significance
rpoB 760406 c.600G>T synonymous_variant 0.36 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.4 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.34 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.36 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.23 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.27 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.26 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.24 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.26 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.26 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.3 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.3 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.3 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.23 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.26 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.25 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.24 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 0.24 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.25 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.25 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.25 rifampicin
rpoB 760784 c.978G>T synonymous_variant 0.25 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.27 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.26 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.24 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.25 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.25 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.21 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.21 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.22 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.24 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.18 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.27 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.16 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.26 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.28 rifampicin Uncertain significance
rpoB 760982 c.1176G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.19 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.18 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.44 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 0.25 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.34 rifampicin
rpoB 761288 c.1482G>T synonymous_variant 0.38 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.29 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.3 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.29 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.31 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.27 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.27 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.19 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.26 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.19 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.32 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.23 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.2 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.17 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.17 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 0.16 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.17 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.18 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.18 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.17 rifampicin
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 0.18 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 0.17 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.16 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.18 rifampicin
rpoB 761892 p.Ile696Val missense_variant 0.16 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.2 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.2 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.2 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.21 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.21 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.29 rifampicin
rpoB 762030 p.Thr742Ser missense_variant 0.24 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762057 p.Ile751Val missense_variant 0.23 rifampicin Uncertain significance
rpoB 762062 c.2256T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 0.28 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 762084 c.2278_2280delGCGinsCC frameshift_variant&missense_variant 0.29 rifampicin
rpoB 762098 c.2292C>G synonymous_variant 0.35 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.64 rifampicin Uncertain significance
rpoB 762122 p.Asp772Glu missense_variant 0.36 rifampicin
rpoB 762125 p.Glu773Asp missense_variant 0.35 rifampicin
rpoB 762128 c.2322G>C synonymous_variant 0.36 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.62 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762137 c.2331C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.64 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.65 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 0.4 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762177 p.Arg791Gly missense_variant 0.38 rifampicin
rpoB 762181 p.Asp792Ala missense_variant 0.38 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762189 p.Ile795Val missense_variant 0.41 rifampicin
rpoB 762209 c.2403C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.42 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>C synonymous_variant 0.32 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.29 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.29 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 0.3 rifampicin
rpoB 762284 c.2478G>T synonymous_variant 0.23 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762299 c.2493G>C synonymous_variant 0.23 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.44 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.36 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.38 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.37 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 0.34 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.4 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.36 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.34 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.31 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.37 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.29 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.31 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.31 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.3 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.23 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.23 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.2 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.2 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.2 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.18 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.16 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.14 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.23 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.38 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.6 rifampicin Not assoc w R
rpoB 763031 c.3225T>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.21 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.17 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.22 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.26 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.26 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 0.24 rifampicin
rpoC 763199 c.-171G>C upstream_gene_variant 0.2 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.19 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.18 rifampicin
rpoC 763206 c.-164_-163delAGinsTC upstream_gene_variant 0.18 rifampicin
rpoC 763217 c.-153G>C upstream_gene_variant 0.18 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.18 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.19 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.18 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.18 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.18 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.15 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.26 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.23 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.22 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.24 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.24 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.25 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.16 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.28 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>A synonymous_variant 0.38 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.39 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.55 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.45 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.44 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.45 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>G synonymous_variant 0.64 rifampicin
rpoC 763622 c.253_255delGCCinsTG frameshift_variant&missense_variant 0.51 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763642 c.273G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.23 rifampicin
rpoC 763669 c.300C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763686 p.Tyr106Phe missense_variant 0.49 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.43 rifampicin
rpoC 763709 c.340_342delCTGinsTC frameshift_variant&missense_variant 0.27 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.68 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.39 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.27 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.29 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.36 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.3 rifampicin
rpoC 763751 p.Ile128Val missense_variant 0.26 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763768 c.399C>G synonymous_variant 0.21 rifampicin
rpoC 763772 p.Val135Met missense_variant 0.2 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.34 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.32 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.28 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.27 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.28 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.29 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.29 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.27 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.27 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.26 rifampicin
rpoC 763882 c.513G>A synonymous_variant 0.26 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.25 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.25 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.23 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.2 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.21 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.2 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.21 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAC frameshift_variant&missense_variant 0.16 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.16 rifampicin
rpoC 764207 p.Val280Ile missense_variant 0.16 rifampicin
rpoC 764227 c.858G>T synonymous_variant 0.17 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.27 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.26 rifampicin
rpoC 764263 c.894G>T synonymous_variant 0.28 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.28 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.31 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.3 rifampicin
rpoC 764338 p.Glu323Asp missense_variant 0.19 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.25 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.26 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.5 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.51 rifampicin
rpoC 764419 c.1050C>G synonymous_variant 0.3 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCT frameshift_variant&missense_variant 0.49 rifampicin
rpoC 764440 c.1071G>C synonymous_variant 0.3 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.29 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.45 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.16 rifampicin
rpoC 764491 c.1122G>C synonymous_variant 0.42 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764498 p.Ser377Ala missense_variant 0.33 rifampicin
rpoC 764507 p.Ala380Ser missense_variant 0.36 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 0.45 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 0.52 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 0.53 rifampicin
rpoC 764573 c.1204_1206delCTTinsAC frameshift_variant&missense_variant 0.53 rifampicin
rpoC 764578 c.1209C>G synonymous_variant 0.54 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.53 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.53 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.55 rifampicin
rpoC 764605 c.1236G>T synonymous_variant 0.65 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 0.45 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764706 p.Leu446His missense_variant 0.45 rifampicin
rpoC 764713 c.1344G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764737 c.1368G>C synonymous_variant 0.48 rifampicin
rpoC 764746 c.1377G>C synonymous_variant 0.61 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.49 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764785 c.1416C>G synonymous_variant 0.44 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.42 rifampicin
rpoC 764801 c.1433_1434insTG frameshift_variant 0.49 rifampicin
rpoC 764804 c.1436_1437delAG frameshift_variant 0.38 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.28 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.37 rifampicin
rpoC 764813 p.Gln482Val missense_variant 0.37 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764843 p.Ala492Thr missense_variant 0.35 rifampicin
rpoC 764854 c.1485G>C synonymous_variant 0.31 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.39 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.51 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.15 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.39 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.39 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.31 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.19 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765358 p.Met663Ile missense_variant 0.17 rifampicin Uncertain significance
rpoC 765361 c.1992C>G synonymous_variant 0.17 rifampicin
rpoC 765383 c.2014_2016delATGinsCC frameshift_variant&missense_variant 0.27 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 0.25 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.2 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.2 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.23 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.2 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.25 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.26 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.35 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.23 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.21 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.21 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.17 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.17 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.18 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.15 rifampicin
rpoC 765814 c.2445A>C synonymous_variant 0.16 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.16 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.31 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.32 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.35 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.33 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.29 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.26 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.24 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.22 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.26 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766690 c.3321G>C synonymous_variant 0.19 rifampicin
rpoC 766694 c.3325_3327delCAGinsGC frameshift_variant&missense_variant 0.17 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.24 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 0.24 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.23 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.25 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.24 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.22 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.22 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.2 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.2 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.2 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 766981 c.3612T>C synonymous_variant 0.26 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.26 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.26 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.31 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.32 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.25 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 775814 c.2667C>G synonymous_variant 0.19 clofazimine
bedaquiline
mmpL5 775817 c.2664T>C synonymous_variant 0.2 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.16 clofazimine
bedaquiline
mmpL5 775829 c.2652C>G synonymous_variant 0.22 clofazimine
bedaquiline
mmpL5 775834 p.Ala883Ser missense_variant 0.17 clofazimine
bedaquiline
mmpL5 775838 c.2643G>C synonymous_variant 0.18 clofazimine
bedaquiline
mmpL5 775847 c.2634G>T synonymous_variant 0.26 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 0.23 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.31 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 0.24 clofazimine
bedaquiline
mmpL5 775877 c.2604C>G synonymous_variant 0.21 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsTG frameshift_variant&missense_variant 0.22 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.26 clofazimine
bedaquiline
mmpL5 775892 c.2589C>T synonymous_variant 0.25 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.34 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.26 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 0.26 clofazimine
bedaquiline
mmpL5 775916 c.2565T>C synonymous_variant 0.29 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.26 clofazimine
bedaquiline
mmpL5 775924 c.2557C>T synonymous_variant 0.27 clofazimine Not assoc w R - Interim
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.36 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.25 clofazimine
bedaquiline
mmpL5 775970 c.2511G>C synonymous_variant 0.24 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.25 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.28 clofazimine
bedaquiline
mmpL5 775994 c.2485_2487delATCinsCG frameshift_variant&missense_variant 0.21 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775997 c.2484T>G synonymous_variant 0.21 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.21 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 0.21 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.21 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.21 clofazimine
bedaquiline
mmpL5 776045 c.2436G>C synonymous_variant 0.16 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776182 p.Asp767Asn missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.16 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.18 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.16 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.21 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.23 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.22 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.22 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.28 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.28 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.26 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 0.23 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 0.24 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 0.24 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.29 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.32 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.31 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.27 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.3 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.29 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.31 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.29 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.27 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.31 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.32 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.32 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.36 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.36 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.39 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.35 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.33 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.32 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.3 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.31 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.2 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.25 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.26 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.28 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.29 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.29 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.28 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.28 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.28 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.3 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.34 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.34 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.35 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.35 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.36 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.36 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.26 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.24 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.25 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.2 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.29 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.21 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.2 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.2 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.28 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.17 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 0.99 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1304526 c.1596T>A synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304649 c.1719C>T synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.26 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
sigE 1364898 c.486C>T synonymous_variant 0.17 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.16 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.16 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.16 pyrazinamide
sigE 1364931 c.519C>T synonymous_variant 0.16 pyrazinamide
sigE 1364950 c.538_540delGCAinsTC frameshift_variant&missense_variant 0.17 pyrazinamide Uncertain significance
sigE 1364964 c.552T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.22 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.29 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.3 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.26 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472434 n.589_590insC non_coding_transcript_exon_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472438 n.594delC non_coding_transcript_exon_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.19 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>A non_coding_transcript_exon_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.19 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.5 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472469 n.625_626insATC non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472473 n.629_631delCGA non_coding_transcript_exon_variant 0.18 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472583 n.738T>C non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472701 n.856T>A non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.26 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.26 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.26 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.36 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443_1444delCTinsGTTCG non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.16 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473722 n.65G>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1473750 n.93C>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473782 n.125A>G non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1473788 n.131A>C non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1473797 n.140G>C non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473845 n.188G>C non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474053 n.396G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.15 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474108 n.451C>G non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474292 n.635_650delTTCCTCTCCGGAGGAGinsGGCT non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474309 n.653delT non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474356 n.699T>A non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474381 n.724T>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475068 n.1411A>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475078 n.1421T>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475174 n.1517C>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1475176 n.1519G>A non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1475187 n.1530C>T non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475382 n.1725A>G non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475395 n.1738T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid Uncertain significance
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.72 capreomycin
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1475604 n.1950_1951delAT non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475608 n.1951T>G non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475634 n.1977_1981delGGATCinsTGGA non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475752 n.2095C>G non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.79 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.55 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.57 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.57 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.75 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.76 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.72 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.8 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.37 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rpsA 1833589 c.48A>C synonymous_variant 0.2 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.2 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.2 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.2 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.28 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.23 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.24 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.26 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.28 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.39 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.33 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.29 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.34 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.28 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
rpsA 1833709 c.168C>T synonymous_variant 0.35 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.35 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.4 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.3 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.32 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.41 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.38 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.37 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.38 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.3 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.4 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.36 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.36 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.46 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.47 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.35 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.46 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.46 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.48 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.34 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.28 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.31 pyrazinamide
rpsA 1833893 p.Ala118Lys missense_variant 0.28 pyrazinamide
rpsA 1833896 p.Leu119Ile missense_variant 0.28 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.19 pyrazinamide
rpsA 1833905 p.Lys122Glu missense_variant 0.27 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.28 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.28 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.29 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.58 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.19 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 0.44 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.5 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.39 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.55 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.59 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.38 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.17 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.21 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.61 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.22 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.56 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.33 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.34 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.33 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.19 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.27 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.18 pyrazinamide
rpsA 1834219 c.678C>G synonymous_variant 0.19 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.19 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834243 c.702G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.27 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.31 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.59 pyrazinamide
rpsA 1834307 c.766_768delGACinsCG frameshift_variant&missense_variant 0.31 pyrazinamide Uncertain significance
rpsA 1834318 c.777C>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
rpsA 1834327 c.786G>T synonymous_variant 0.35 pyrazinamide
rpsA 1834330 c.789C>G synonymous_variant 0.28 pyrazinamide
rpsA 1834340 c.799_801delATGinsTC frameshift_variant&missense_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834345 c.804C>T synonymous_variant 0.28 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>G synonymous_variant 0.16 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.39 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.46 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.46 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.29 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.5 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.33 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.54 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.54 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.36 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.33 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.22 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.18 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.27 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.26 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.17 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.23 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.15 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.22 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.21 pyrazinamide
rpsA 1834776 p.Ala412Asp missense_variant 0.21 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.21 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.2 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.17 linezolid
tsnR 1853372 c.-234A>G upstream_gene_variant 0.16 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.15 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.16 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.16 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.16 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.15 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155696 p.Ala139Val missense_variant 0.16 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.18 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.17 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.17 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.18 isoniazid
katG 2155747 p.Ala122Gly missense_variant 0.18 isoniazid
katG 2155749 c.363C>T synonymous_variant 0.18 isoniazid Not assoc w R - Interim
katG 2155752 c.360C>T synonymous_variant 0.18 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.2 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.19 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.17 isoniazid
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
kasA 2517941 c.-174C>G upstream_gene_variant 0.27 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.23 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.26 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.19 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.21 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 0.14 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.17 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.16 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.16 isoniazid
kasA 2518716 p.Pro201Arg missense_variant 0.15 isoniazid
kasA 2518726 c.612G>A synonymous_variant 0.15 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.16 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.17 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.17 isoniazid
Rv2477c 2783311 c.732T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2752c 3065126 p.Ser356Ala missense_variant 0.15 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.15 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>G synonymous_variant 0.18 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.17 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065154 c.1038G>A synonymous_variant 0.15 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065160 c.1032C>T synonymous_variant 0.15 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
ald 3086728 c.-92C>T upstream_gene_variant 1.0 cycloserine
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0 pyrazinamide Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 0.99 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625183 c.-273G>C upstream_gene_variant 0.17 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.17 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 0.17 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.21 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625243 c.-333T>G upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3625252 c.1362G>C synonymous_variant 0.21 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>C upstream_gene_variant 0.2 bedaquiline
rifampicin
lpqB 3625258 c.-348G>T upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3625264 c.1350C>T synonymous_variant 0.19 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625267 c.1347T>C synonymous_variant 0.19 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.19 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 0.19 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.19 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.19 bedaquiline
rifampicin
lpqB 3625297 c.-387C>G upstream_gene_variant 0.18 bedaquiline
rifampicin
lpqB 3625312 c.-402G>C upstream_gene_variant 0.16 bedaquiline
rifampicin
lpqB 3625663 c.-753G>A upstream_gene_variant 0.17 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3625711 c.903C>T synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.25 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.2 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3625753 p.Ala287Gln missense_variant 0.22 bedaquiline
rifampicin
lpqB 3625762 c.-852A>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625804 c.808_810delAGGinsCC frameshift_variant&missense_variant 0.24 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625822 c.-912C>T upstream_gene_variant 0.27 bedaquiline
rifampicin
lpqB 3625828 c.-918G>C upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrB 3625837 c.777C>G synonymous_variant 0.2 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 0.19 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.17 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 0.18 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626562 p.Pro18Ser missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3626704 c.-91C>T upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.16 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.22 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626969 c.381C>T synonymous_variant 0.19 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.2 bedaquiline
rifampicin Uncertain significance
mtrB 3626999 c.-386G>C upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrB 3627002 c.-389G>C upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrB 3627005 c.-392G>A upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 0.22 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.2 bedaquiline
rifampicin
mtrB 3627044 c.-431C>T upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrB 3627062 c.-449G>A upstream_gene_variant 0.18 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.22 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.2 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.2 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.18 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.23 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 0.17 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.2 bedaquiline
rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.18 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.22 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.18 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.17 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.23 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.19 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.24 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.24 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.25 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.21 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.23 rifampicin
rpoA 3877875 c.633T>A synonymous_variant 0.25 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.24 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.27 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3877899 c.609C>T synonymous_variant 0.22 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.25 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.31 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.32 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>C synonymous_variant 0.31 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 0.28 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.3 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.27 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.31 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.3 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>G synonymous_variant 0.28 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.32 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.33 rifampicin
rpoA 3878061 c.447G>A synonymous_variant 0.33 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.37 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.32 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.37 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.42 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.35 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.39 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.31 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>A synonymous_variant 0.33 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.47 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878238 c.270C>T synonymous_variant 0.29 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 0.28 rifampicin
rpoA 3878247 c.261G>A synonymous_variant 0.28 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.29 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.24 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.33 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.25 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.22 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.21 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.22 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
clpC1 4038383 c.2322G>C synonymous_variant 0.15 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.15 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.15 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4038519 p.Arg729Gln missense_variant 0.16 pyrazinamide
clpC1 4038584 c.2121G>A synonymous_variant 0.16 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.17 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.22 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.23 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.25 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.23 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.23 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.21 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.21 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.27 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.27 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.25 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.25 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.25 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.25 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.28 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.31 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.34 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.19 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.35 pyrazinamide
clpC1 4038776 p.Glu643Asp missense_variant 0.22 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.17 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.17 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Ile missense_variant 0.22 pyrazinamide
clpC1 4038799 p.Asn636Asp missense_variant 0.21 pyrazinamide
clpC1 4038801 p.Tyr635Phe missense_variant 0.21 pyrazinamide
clpC1 4038805 p.Ile634Val missense_variant 0.2 pyrazinamide Uncertain significance
clpC1 4038809 p.Gln632Pro missense_variant 0.2 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.43 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.2 pyrazinamide
clpC1 4038826 p.Ile627Val missense_variant 0.21 pyrazinamide
clpC1 4038835 p.Phe624Leu missense_variant 0.2 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.43 pyrazinamide
clpC1 4038849 p.Phe619Tyr missense_variant 0.19 pyrazinamide
clpC1 4038855 p.Lys617Arg missense_variant 0.19 pyrazinamide
clpC1 4038857 c.1848C>T synonymous_variant 0.19 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4038863 c.1842G>C synonymous_variant 0.18 pyrazinamide
clpC1 4038866 p.Lys613Ala missense_variant 0.18 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.17 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 0.29 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.35 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.27 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.22 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.26 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.35 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.35 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.35 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.33 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.35 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.39 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.4 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4039064 c.1641C>T synonymous_variant 0.34 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.35 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.34 pyrazinamide
clpC1 4039100 c.1605C>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4039103 c.1602T>C synonymous_variant 0.26 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.29 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.3 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.38 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.37 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.36 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.36 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.37 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.3 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.32 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.27 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.27 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.26 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 0.26 pyrazinamide
clpC1 4039320 p.Ala462Gly missense_variant 0.24 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 0.25 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.24 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.22 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4039361 c.1344C>G synonymous_variant 0.27 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.29 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.28 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.24 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.27 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.36 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.39 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.39 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.36 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.39 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.39 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.4 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.3 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.14 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.53 pyrazinamide
clpC1 4039550 c.1155G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039564 p.Ala381Ser missense_variant 0.16 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.47 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Cys missense_variant 0.4 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4039580 c.1125C>G synonymous_variant 0.19 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.52 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.6 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.3 pyrazinamide
clpC1 4039642 p.Thr355Ala missense_variant 0.23 pyrazinamide
clpC1 4039647 p.Glu353Pro missense_variant 0.21 pyrazinamide
clpC1 4039649 c.1054_1056delGTGinsCC frameshift_variant&missense_variant 0.54 pyrazinamide
clpC1 4039652 c.1051_1053delACGinsTC frameshift_variant&missense_variant 0.28 pyrazinamide
clpC1 4039661 p.Gly348Ala missense_variant 0.26 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039670 c.1033_1035delGTGinsAC frameshift_variant&missense_variant 0.45 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.29 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039697 c.1006_1008delGCCinsCG frameshift_variant&synonymous_variant 0.23 pyrazinamide
clpC1 4039711 p.Ile332Val missense_variant 0.28 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.29 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.55 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039736 c.969C>G synonymous_variant 0.24 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.25 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.46 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.45 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.44 pyrazinamide
clpC1 4039766 c.939T>G synonymous_variant 0.17 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039773 p.Lys311Met missense_variant 0.16 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.45 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.17 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.29 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.42 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.45 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.38 pyrazinamide
clpC1 4039832 c.873C>A synonymous_variant 0.21 pyrazinamide
clpC1 4039838 c.865_867delCTGinsAC frameshift_variant&missense_variant 0.19 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.51 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039871 c.834C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039875 p.Asn277Arg missense_variant 0.18 pyrazinamide
clpC1 4039883 c.822G>A synonymous_variant 0.23 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.25 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.45 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.24 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.4 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.43 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.55 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039985 c.720G>A synonymous_variant 0.29 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.42 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.5 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.49 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>T synonymous_variant 0.29 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.39 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.2 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.19 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040171 c.534C>G synonymous_variant 0.16 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.17 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.2 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.22 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.21 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.2 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.2 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.23 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.23 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.22 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.24 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>A synonymous_variant 0.25 pyrazinamide
clpC1 4040492 c.213G>A synonymous_variant 0.27 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.27 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.27 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.22 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.24 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.24 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.22 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.22 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.24 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.24 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.24 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.23 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.22 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.2 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.2 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.2 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
panD 4044180 p.Asp34Glu missense_variant 0.17 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.17 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.17 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.17 pyrazinamide
glpK 4138661 c.1095T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.22 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138696 p.Pro354Thr missense_variant 0.22 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138697 c.1059C>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138727 c.1029C>G synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138747 c.1009C>T synonymous_variant 0.26 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.26 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>A synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>A synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138781 c.975G>T synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138799 c.957T>G synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 0.14 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139585 c.171G>A synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139594 c.162C>A synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139602 c.154C>A synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139609 c.147C>T synonymous_variant 0.16 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4243460 c.228C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247470 c.957T>C synonymous_variant 0.2 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.23 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.23 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 0.24 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.23 ethambutol
embB 4247536 c.1023C>G synonymous_variant 0.22 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.18 ethambutol
embB 4247555 c.1042_1044delCTGinsAC frameshift_variant&missense_variant 0.18 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.19 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.19 ethambutol
embB 4247578 c.1065_1066insATCTGT conservative_inframe_insertion 0.19 ethambutol
embB 4247581 c.1069_1074delGCCGGG conservative_inframe_deletion 0.21 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embB 4248112 c.1599C>G synonymous_variant 0.2 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.23 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.23 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.24 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.24 ethambutol
embB 4248143 c.1630_1632delTTGinsAC frameshift_variant&missense_variant 0.24 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.26 ethambutol
embB 4248167 p.Thr552Ala missense_variant 0.27 ethambutol
embB 4248170 p.Ala553Ser missense_variant 0.28 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.28 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.32 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.32 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.33 ethambutol Uncertain significance
embB 4248220 c.1707A>G synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.27 ethambutol Uncertain significance
embB 4248233 c.1720C>T synonymous_variant 0.24 ethambutol
embB 4248242 p.Val577Ile missense_variant 0.25 ethambutol
aftB 4267647 p.Asp397Gly missense_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407620 p.Tyr195His missense_variant 1.0 streptomycin Not assoc w R
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Not assoc w R