TB-Profiler result

Run: ERR403298

Summary

Run ID: ERR403298

Sample name:

Date: 2024-04-16T12:25:32.378410

Number of reads: 1100555

Percentage reads mapped: 32.25

Median coverage: 28.0

Strain: M.canetti;lineage4.2

Spoligotype:

Drug-resistance: MDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.2 Euro-American None 0.11
lineage4 Euro-American None 0.08
M.canetti M.canetti None 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Thr437Ala Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.865_867delCACinsAT Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.562_564delTTGinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1144_1146delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1270_1272delCTGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1591_1593delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.706_708delGCAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1150_1152delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.316_318delGTGinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.865_867delCACinsAT Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsCG frameshift_variant&missense_variant 0.63 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.84 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303492 c.562_564delTTGinsCT frameshift_variant&synonymous_variant 0.58 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 0.78 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.7 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsAG frameshift_variant&missense_variant 0.32 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304074 c.1144_1146delGCCinsTG frameshift_variant&missense_variant 0.48 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304200 c.1270_1272delCTGinsTC frameshift_variant&missense_variant 0.52 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304521 c.1591_1593delCTGinsGA frameshift_variant&missense_variant 0.5 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.62 isoniazid Assoc w R High-level resistance
pepQ 2859552 c.865_867delCACinsAT frameshift_variant&synonymous_variant 0.63 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
fbiA 3641248 c.706_708delGCAinsAC frameshift_variant&missense_variant 0.53 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642684 c.1150_1152delTTGinsCA frameshift_variant&missense_variant 0.45 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987159 c.316_318delGTGinsAT frameshift_variant&missense_variant 0.5 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.83 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.7 ethambutol Mutation from literature
embB 4247822 p.Thr437Ala missense_variant 0.54 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 0.33 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.33 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 0.43 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 0.43 isoniazid Uncertain significance
dnaA 753 c.753C>T synonymous_variant 0.43 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.45 isoniazid
dnaA 762 c.762C>T synonymous_variant 0.43 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.48 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.58 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.58 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 0.55 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.5 isoniazid Uncertain significance
dnaA 810 c.810C>G synonymous_variant 0.48 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.52 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.58 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.69 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.7 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 849 c.849A>G synonymous_variant 0.71 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.78 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.76 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.7 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.7 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.72 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.69 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.71 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.7 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.64 isoniazid
dnaA 939 c.939C>A synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 945 c.945G>A synonymous_variant 0.56 isoniazid
dnaA 1003 c.1003C>T synonymous_variant 0.43 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.74 isoniazid
dnaA 1059 c.1059C>A synonymous_variant 0.78 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.71 isoniazid
dnaA 1083 c.1083C>T synonymous_variant 0.73 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.64 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.56 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 0.45 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 1179 c.1179G>C synonymous_variant 0.57 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.57 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 0.57 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.58 isoniazid
dnaA 1200 c.1200C>T synonymous_variant 0.6 isoniazid
dnaA 1206 c.1206G>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Thr missense_variant 0.7 isoniazid
dnaA 1222 p.Thr408Ala missense_variant 0.7 isoniazid Uncertain significance
dnaA 1245 c.1245G>C synonymous_variant 0.78 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.8 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.64 isoniazid
dnaA 1281 c.1281C>G synonymous_variant 0.62 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.62 isoniazid
dnaA 1299 c.1299G>A synonymous_variant 0.53 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.52 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 0.4 isoniazid
dnaA 1350 c.1350G>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 0.33 isoniazid
dnaA 1356 c.1356T>G synonymous_variant 0.37 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.48 isoniazid
dnaA 1374 c.1374G>T synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1375 c.1375T>C synonymous_variant 0.5 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.61 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.61 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.62 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.66 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.69 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.68 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.67 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.67 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.62 isoniazid
dnaA 1458 c.1458G>A synonymous_variant 0.58 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.58 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 1488 c.1488A>G synonymous_variant 0.48 isoniazid
dnaA 1494 c.1494C>G synonymous_variant 0.45 isoniazid
dnaA 1497 c.1497T>A synonymous_variant 0.42 isoniazid
dnaA 1498 c.1498_1500delCGCinsAG frameshift_variant&missense_variant 0.4 isoniazid Uncertain significance
gyrB 5238 c.-2T>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 5254 c.15A>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 5284 c.45G>A synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 5293 c.54C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5302 c.63A>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 5305 c.66G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 5308 c.69G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5359 c.120C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin
gyrB 5377 c.138T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5422 c.183T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5425 c.186A>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5426 p.Thr63Ala missense_variant 0.67 levofloxacin
moxifloxacin
gyrB 5431 c.192A>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5434 c.195G>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrB 5436 p.Asn66Ser missense_variant 0.64 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 5440 c.201A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 5449 c.210T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5455 c.216T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5470 c.231C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5485 c.246C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrB 5488 c.249C>A synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5491 c.252T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 5500 c.261C>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 5502 p.Thr88Met missense_variant 0.62 levofloxacin
moxifloxacin
gyrB 5527 c.288C>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrB 5542 c.303A>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrB 5545 c.306A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 5548 c.309A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5551 c.312T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 5560 c.321C>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 5569 c.330C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrB 5572 c.333G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 5767 c.528C>T synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5771 p.Ala178Asn missense_variant 0.71 levofloxacin
moxifloxacin
gyrB 5779 c.540C>T synonymous_variant 0.75 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 5782 c.543A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 5788 c.549G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5791 c.552A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 5812 c.573C>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5815 c.576C>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5819 c.580C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5824 c.585A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 5836 c.597C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5851 c.612G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5860 c.621C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 5869 c.630C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5870 p.Glu211Gln missense_variant 0.8 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5884 c.645A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrB 6013 c.774G>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 6022 c.783G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6025 c.786A>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6037 c.798C>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6049 c.810G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6079 c.840C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrB 6085 c.846C>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.77 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.88 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.76 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6421 c.-881C>T upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6565 c.-737G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6625 c.-677G>A upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>T synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6826 c.-476G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6886 c.-416C>T upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>T upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>A upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 7151 c.1912C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7165 c.-137C>A upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7207 c.-95C>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7219 c.-83C>A upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7231 c.-71C>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7523 c.222C>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7652 c.351C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7703 c.402G>A synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7715 c.414G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 7940 c.639G>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7941 p.Glu214Thr missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7958 c.657C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.62 levofloxacin
moxifloxacin
gyrA 7970 c.669T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7973 c.672A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7988 c.687G>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7997 c.696A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8000 c.699G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8030 c.729C>A synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8042 c.741C>T synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8048 c.747C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8105 c.804G>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsGG frameshift_variant&missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.41 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8282 c.981G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 0.78 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.75 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.72 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.84 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9065 c.1764C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9197 c.1896G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9218 c.1917C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.91 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9476 c.2175G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9585 c.2284T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 0.77 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9722 c.2421C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>A synonymous_variant 0.69 levofloxacin
moxifloxacin
Rv0010c 13891 c.-333G>C upstream_gene_variant 0.58 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.62 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.62 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.62 isoniazid
fgd1 490781 c.-2T>G upstream_gene_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 490782 c.-1G>A upstream_gene_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.79 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 490809 c.27A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490853 p.Ala24Gly missense_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 490863 c.81C>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490945 c.163C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 490984 p.Leu68Val missense_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491154 p.Glu124Asp missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fgd1 491265 c.483G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.7 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491298 c.516C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491331 c.549G>A synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.5 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>A synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
mshA 574688 c.-660G>C upstream_gene_variant 0.35 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.33 ethionamide
isoniazid
mshA 574703 c.-645C>T upstream_gene_variant 0.32 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 0.33 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 0.35 ethionamide
isoniazid
mshA 574721 c.-627C>G upstream_gene_variant 0.35 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 0.4 ethionamide
isoniazid
mshA 574738 c.-610_-609delGTinsAC upstream_gene_variant 0.38 ethionamide
isoniazid
mshA 574763 c.-585T>C upstream_gene_variant 0.4 ethionamide
isoniazid Uncertain significance
mshA 575506 c.159C>T synonymous_variant 0.53 ethionamide
isoniazid
mshA 575512 c.165A>G synonymous_variant 0.6 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.61 ethionamide
isoniazid
mshA 575530 c.183C>G synonymous_variant 0.67 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.68 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.71 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575548 c.201C>A synonymous_variant 0.77 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.79 ethionamide
isoniazid
mshA 575586 p.Ala80Gly missense_variant 0.77 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575593 c.246G>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 0.75 ethionamide
isoniazid
mshA 575629 c.282A>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 575633 c.286_288delGCAinsAG frameshift_variant&missense_variant 0.76 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575652 p.Arg102Gln missense_variant 0.76 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575662 c.315C>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.76 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575686 c.339G>A synonymous_variant 0.79 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575692 c.345G>A synonymous_variant 0.82 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.78 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.79 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 0.81 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.77 ethionamide
isoniazid
mshA 575824 c.477T>C synonymous_variant 0.76 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.8 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 0.78 ethionamide
isoniazid
mshA 575878 c.531A>T synonymous_variant 0.76 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.77 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.73 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 0.68 ethionamide
isoniazid Not assoc w R - Interim
mshA 575908 c.561A>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.81 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 0.83 ethionamide
isoniazid
mshA 576460 c.1113C>G synonymous_variant 0.39 ethionamide
isoniazid
mshA 576463 c.1116G>T synonymous_variant 0.37 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 576469 c.1122G>C synonymous_variant 0.43 ethionamide
isoniazid
mshA 576481 c.1134C>G synonymous_variant 0.47 ethionamide
isoniazid
mshA 576490 c.1143G>T synonymous_variant 0.53 ethionamide
isoniazid
mshA 576511 c.1164C>G synonymous_variant 0.47 ethionamide
isoniazid
mshA 576517 c.1170G>A synonymous_variant 0.39 ethionamide
isoniazid
mshA 576523 c.1176G>A synonymous_variant 0.39 ethionamide
isoniazid
ccsA 619624 c.-267C>T upstream_gene_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619648 c.-243C>G upstream_gene_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 619681 c.-210G>A upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194A>C upstream_gene_variant 0.68 capreomycin
amikacin
kanamycin
ccsA 619744 c.-147A>G upstream_gene_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620214 c.324C>A synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620314 c.424C>T synonymous_variant 0.84 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620325 c.435G>T synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620404 c.514C>T synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.84 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620479 c.589_591delCTTinsTG frameshift_variant&missense_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620487 c.597C>G synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>C synonymous_variant 0.61 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620571 c.681A>G synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>A synonymous_variant 0.79 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620622 c.732G>C synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>T synonymous_variant 0.76 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 0.76 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.68 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>T synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 620760 c.870C>G synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.69 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620829 c.939G>T synonymous_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620838 c.948C>T synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620839 c.949C>T synonymous_variant 0.55 capreomycin
amikacin
kanamycin
Rv0565c 656067 c.1404C>T synonymous_variant 0.56 ethionamide
Rv0565c 656073 p.Leu466Phe missense_variant 0.71 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 0.73 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 0.76 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.76 ethionamide
Rv0565c 656103 c.1368G>A synonymous_variant 0.74 ethionamide
Rv0565c 656112 c.1359C>A synonymous_variant 0.7 ethionamide
Rv0565c 656116 p.Lys452Arg missense_variant 0.67 ethionamide
Rv0565c 656129 p.Tyr448His missense_variant 0.59 ethionamide
Rv0565c 656131 p.Pro447Leu missense_variant 0.56 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 0.56 ethionamide
Rv0565c 656136 c.1335G>C synonymous_variant 0.6 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 0.56 ethionamide
Rv0565c 656277 c.1194C>T synonymous_variant 0.47 ethionamide
Rv0565c 656282 c.1189C>T synonymous_variant 0.47 ethionamide Not assoc w R - Interim
Rv0565c 656295 c.1176C>T synonymous_variant 0.45 ethionamide
Rv0565c 656301 c.1170C>T synonymous_variant 0.45 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.45 ethionamide
Rv0565c 656922 c.547_549delATCinsGG frameshift_variant&missense_variant 0.55 ethionamide Uncertain significance
Rv0565c 656936 p.Thr179Ala missense_variant 0.46 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.43 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 0.43 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 0.43 ethionamide
Rv0565c 656964 c.507C>G synonymous_variant 0.5 ethionamide
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657171 c.300T>C synonymous_variant 0.47 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.55 ethionamide
Rv0565c 657196 p.Asp92Thr missense_variant 0.55 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 0.62 ethionamide
Rv0565c 657207 c.264G>A synonymous_variant 0.68 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 0.75 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.7 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.69 ethionamide Uncertain significance
Rv0565c 657243 c.228C>A synonymous_variant 0.69 ethionamide
Rv0565c 657267 c.202_204delTCGinsAGC synonymous_variant 0.77 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.77 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.75 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.74 ethionamide
Rv0565c 657340 p.Ala44Glu missense_variant 0.61 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 0.53 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.5 ethionamide
Rv0565c 657587 c.-117C>T upstream_gene_variant 0.57 ethionamide
Rv0565c 657590 c.-120G>C upstream_gene_variant 0.57 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.59 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 0.75 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.75 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsAT upstream_gene_variant 0.76 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.86 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.84 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 0.82 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.82 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.89 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.76 ethionamide
hadA 731687 c.-243G>C upstream_gene_variant 0.39 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 0.39 isoniazid
hadA 731693 c.-237_-236insGTTTGACACCAGAT upstream_gene_variant 0.38 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.43 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.57 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.62 isoniazid
hadA 731738 c.-192G>T upstream_gene_variant 0.81 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.81 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.84 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.87 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 0.86 isoniazid
hadA 731837 c.-93C>T upstream_gene_variant 0.81 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.79 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.7 isoniazid
hadA 731858 c.-72G>A upstream_gene_variant 0.68 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.56 isoniazid
hadA 732247 c.318C>T synonymous_variant 0.65 isoniazid
hadA 732250 c.321C>G synonymous_variant 0.72 isoniazid
hadA 732263 p.Val112Met missense_variant 0.72 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.77 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.75 isoniazid
hadA 732322 p.Glu131Asp missense_variant 0.8 isoniazid
hadA 732329 c.400_402delCTCinsAT frameshift_variant&missense_variant 0.82 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 0.85 isoniazid
hadA 732361 c.432C>T synonymous_variant 0.89 isoniazid
hadA 732376 c.447T>C synonymous_variant 0.82 isoniazid
hadA 732378 c.449_450insGGA disruptive_inframe_insertion 0.84 isoniazid
hadA 732381 p.Glu151Val missense_variant 0.86 isoniazid
hadA 732391 c.462T>A synonymous_variant 0.91 isoniazid
nusG 734352 c.99T>C synonymous_variant 0.64 rifampicin
nusG 734361 c.108C>T synonymous_variant 0.72 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.78 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.78 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.85 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.88 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.88 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.84 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.82 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.85 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.83 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.8 rifampicin
nusG 734616 c.363C>A synonymous_variant 0.8 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.78 rifampicin
nusG 734631 c.378G>A synonymous_variant 0.74 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.73 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.74 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.75 rifampicin
nusG 734661 c.408A>C synonymous_variant 0.76 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.76 rifampicin
nusG 734670 c.417G>A synonymous_variant 0.81 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.8 rifampicin
nusG 734680 p.Ala143Ser missense_variant 0.79 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.86 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.83 rifampicin
nusG 734712 c.459G>C synonymous_variant 0.83 rifampicin
nusG 734718 c.465G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 0.85 rifampicin
nusG 734722 p.Thr157Ala missense_variant 0.85 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.88 rifampicin
nusG 734733 c.480T>A synonymous_variant 0.91 rifampicin
nusG 734736 c.483C>G synonymous_variant 0.88 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.81 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.81 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.79 rifampicin
nusG 734769 c.516G>A synonymous_variant 0.79 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.8 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.79 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.8 rifampicin
nusG 734793 c.540C>T synonymous_variant 0.81 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.85 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.86 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.85 rifampicin
nusG 734874 c.621G>A synonymous_variant 0.84 rifampicin
nusG 734880 c.627C>T synonymous_variant 0.85 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.8 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.7 rifampicin
nusG 734928 c.675A>G synonymous_variant 0.48 rifampicin
rpoB 759583 c.-224T>G upstream_gene_variant 0.67 rifampicin
rpoB 759587 c.-220T>A upstream_gene_variant 0.7 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 0.82 rifampicin
rpoB 759635 c.-172C>T upstream_gene_variant 0.85 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.85 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.85 rifampicin Uncertain significance
rpoB 759661 c.-146G>C upstream_gene_variant 0.83 rifampicin
rpoB 759670 c.-137C>T upstream_gene_variant 0.83 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.86 rifampicin
rpoB 759676 c.-131A>G upstream_gene_variant 0.85 rifampicin
rpoB 759692 c.-115T>C upstream_gene_variant 0.85 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 0.81 rifampicin
rpoB 759914 c.108T>C synonymous_variant 0.79 rifampicin
rpoB 759920 c.114G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 759929 c.123A>G synonymous_variant 0.82 rifampicin
rpoB 759932 c.126T>G synonymous_variant 0.74 rifampicin
rpoB 759944 c.138A>G synonymous_variant 0.7 rifampicin
rpoB 759945 c.139_141delCTCinsTG frameshift_variant&missense_variant 0.7 rifampicin
rpoB 759956 c.150C>G synonymous_variant 0.67 rifampicin
rpoB 759965 c.159T>C synonymous_variant 0.74 rifampicin
rpoB 759989 c.183G>C synonymous_variant 0.53 rifampicin
rpoB 759991 p.Pro62Gln missense_variant 0.5 rifampicin
rpoB 760059 p.Tyr85Asp missense_variant 0.64 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.68 rifampicin
rpoB 760070 c.264T>A synonymous_variant 0.68 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.82 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.8 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.85 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 0.87 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.84 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 0.86 rifampicin
rpoB 760196 c.390C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.89 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.88 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.86 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.82 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.76 rifampicin
rpoB 760409 c.603C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 0.75 rifampicin
rpoB 760415 c.609C>G synonymous_variant 0.75 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 0.8 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 0.79 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.8 rifampicin
rpoB 760528 p.Gln241Arg missense_variant 0.79 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.79 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.92 rifampicin Uncertain significance
rpoB 760577 c.771G>A synonymous_variant 0.93 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.85 rifampicin
rpoB 760604 c.798G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 0.8 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>A synonymous_variant 0.81 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760664 c.858G>C synonymous_variant 0.75 rifampicin
rpoB 760670 c.864G>C synonymous_variant 0.73 rifampicin
rpoB 760673 c.867G>A synonymous_variant 0.73 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.71 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760727 c.921C>A synonymous_variant 0.69 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760805 c.999G>C synonymous_variant 0.68 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.76 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.87 rifampicin
rpoB 760859 c.1053T>G synonymous_variant 0.88 rifampicin
rpoB 760868 c.1062C>G synonymous_variant 0.91 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.88 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.88 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.88 rifampicin
rpoB 760994 c.1188G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.85 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>A synonymous_variant 0.8 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761066 c.1260G>C synonymous_variant 0.85 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 0.83 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.84 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.85 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.81 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 0.81 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.82 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.82 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 0.81 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.81 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761408 c.1602G>C synonymous_variant 0.61 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 0.69 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.75 rifampicin
rpoB 761438 c.1632G>T synonymous_variant 0.77 rifampicin
rpoB 761441 p.Asp545Glu missense_variant 0.8 rifampicin Uncertain significance
rpoB 761444 c.1638T>C synonymous_variant 0.8 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.8 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 0.8 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.84 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.82 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 0.85 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 0.83 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.87 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.86 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 0.85 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.85 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.89 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.81 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.9 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.88 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.82 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 0.8 rifampicin
rpoB 761735 c.1929C>G synonymous_variant 0.53 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.61 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.63 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.59 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.57 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.52 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.62 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.67 rifampicin
rpoB 761822 c.2016C>G synonymous_variant 0.67 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.65 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.62 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 0.59 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 0.59 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.62 rifampicin
rpoB 761876 c.2070C>A synonymous_variant 0.73 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.8 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.83 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.71 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.71 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 0.71 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.73 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.72 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 0.7 rifampicin
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 0.7 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762071 c.2265C>T synonymous_variant 0.77 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.86 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 0.85 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.87 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.91 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 0.93 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 0.94 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.89 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.88 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.88 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>G synonymous_variant 0.86 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.72 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.71 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.75 rifampicin
rpoB 762369 c.2563_2565delTTGinsCT frameshift_variant&synonymous_variant 0.65 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.7 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.8 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.72 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.74 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.74 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.78 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.84 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 0.76 rifampicin
rpoB 762489 p.Val895Gln missense_variant 0.76 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.79 rifampicin
rpoC 762518 c.-852C>G upstream_gene_variant 0.78 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.73 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.71 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.71 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.8 rifampicin
rpoC 762557 c.-813G>C upstream_gene_variant 0.78 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.72 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.72 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.71 rifampicin
rpoC 762599 c.-771T>A upstream_gene_variant 0.71 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 0.7 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 0.76 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762813 c.3007_3009delATGinsGC frameshift_variant&missense_variant 0.76 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 0.8 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>T upstream_gene_variant 0.78 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.8 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 0.81 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.86 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.84 rifampicin
rpoB 763193 c.3387C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.71 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.67 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.71 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.53 rifampicin Uncertain significance
rpoC 763375 c.6C>A synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.85 rifampicin
rpoC 763430 c.61A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763435 c.66A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 0.9 rifampicin
rpoC 763561 c.192G>A synonymous_variant 0.93 rifampicin
rpoC 763600 c.231C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.96 rifampicin
rpoC 763618 c.249C>A synonymous_variant 0.94 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 0.92 rifampicin
rpoC 763639 c.270G>A synonymous_variant 0.95 rifampicin
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 763666 c.297G>A synonymous_variant 0.92 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.87 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.87 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.86 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.87 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.89 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.87 rifampicin
rpoC 763771 c.402C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.83 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.86 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.84 rifampicin
rpoC 763819 c.450G>C synonymous_variant 0.79 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.67 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.6 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.62 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.62 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.65 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.74 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.72 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.79 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.8 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.76 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.72 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.68 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.73 rifampicin
rpoC 764101 c.732C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.74 rifampicin
rpoC 764119 c.750G>A synonymous_variant 0.79 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.78 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 0.8 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.76 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.75 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.78 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.76 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.72 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.76 rifampicin
rpoC 764272 c.903G>T synonymous_variant 0.78 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.82 rifampicin
rpoC 764317 c.948C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>T synonymous_variant 0.81 rifampicin
rpoC 764347 c.978G>C synonymous_variant 0.85 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.68 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>A synonymous_variant 0.66 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.57 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.52 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.52 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.53 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.56 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.58 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.64 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>A synonymous_variant 0.65 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 0.64 rifampicin
rpoC 764536 c.1167G>A synonymous_variant 0.65 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.61 rifampicin
rpoC 764587 c.1218C>G synonymous_variant 0.76 rifampicin
rpoC 764648 c.1279C>A synonymous_variant 0.86 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 0.84 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.86 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764674 c.1305G>A synonymous_variant 0.84 rifampicin
rpoC 764681 c.1312C>T synonymous_variant 0.85 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.81 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>C synonymous_variant 0.82 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 0.83 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.81 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.8 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 0.8 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.72 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 0.81 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.8 rifampicin
rpoC 764918 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 0.77 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.79 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765067 c.1698G>C synonymous_variant 0.47 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.45 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 0.47 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 0.5 rifampicin
rpoC 765088 c.1719G>C synonymous_variant 0.53 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765100 c.1731G>C synonymous_variant 0.53 rifampicin
rpoC 765103 c.1734G>A synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765115 c.1746G>A synonymous_variant 0.5 rifampicin
rpoC 765122 c.1753C>T synonymous_variant 0.5 rifampicin
rpoC 765287 c.1918C>T synonymous_variant 0.38 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.4 rifampicin
rpoC 765296 c.1927_1929delCCGinsTT frameshift_variant&missense_variant 0.35 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.35 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>G synonymous_variant 0.38 rifampicin
rpoC 765326 p.His653Thr missense_variant 0.35 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.4 rifampicin Uncertain significance
rpoC 765340 p.Gln657His missense_variant 0.53 rifampicin
rpoC 765349 p.Asp660Glu missense_variant 0.55 rifampicin
rpoC 765350 c.1981_1983delGCGinsCC frameshift_variant&missense_variant 0.53 rifampicin
rpoC 765358 p.Met663Ile missense_variant 0.63 rifampicin Uncertain significance
rpoC 765364 p.Glu665Asp missense_variant 0.63 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 0.68 rifampicin
rpoC 765376 c.2007C>G synonymous_variant 0.73 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.78 rifampicin Uncertain significance
rpoC 765395 c.2026C>T synonymous_variant 0.77 rifampicin
rpoC 765405 p.Leu679Pro missense_variant 0.78 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 0.85 rifampicin
rpoC 765430 c.2061G>A synonymous_variant 0.85 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.8 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.8 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 0.8 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765526 c.2157C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>A synonymous_variant 0.78 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.81 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.79 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.79 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.78 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 0.81 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 0.82 rifampicin
rpoC 765610 c.2241C>T synonymous_variant 0.73 rifampicin
rpoC 765612 p.His748Arg missense_variant 0.73 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.76 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765676 c.2307G>A synonymous_variant 0.85 rifampicin
rpoC 765688 c.2319G>C synonymous_variant 0.84 rifampicin
rpoC 765689 c.2320C>T synonymous_variant 0.84 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 0.87 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 0.82 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 0.74 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 0.72 rifampicin
rpoC 765757 c.2388C>T synonymous_variant 0.73 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.72 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.72 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.72 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.73 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>A synonymous_variant 0.8 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.86 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.86 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.88 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 0.85 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 0.8 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.76 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 0.76 rifampicin
rpoC 766070 c.2701C>T synonymous_variant 0.67 rifampicin Not assoc w R
rpoC 766082 p.Ala905Gln missense_variant 0.44 rifampicin
rpoC 766249 c.2880C>A synonymous_variant 0.55 rifampicin
rpoC 766255 c.2886G>T synonymous_variant 0.54 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.69 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.8 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.84 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 0.71 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 766306 c.2937C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.77 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.75 rifampicin
rpoC 766324 c.2955C>T synonymous_variant 0.79 rifampicin
rpoC 766351 c.2982C>G synonymous_variant 0.76 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 0.74 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.71 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.68 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.75 rifampicin
rpoC 766397 c.3028C>T synonymous_variant 0.76 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766417 c.3048C>T synonymous_variant 0.75 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.73 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.87 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.86 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.83 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766519 c.3150C>A synonymous_variant 0.86 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.85 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.86 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.84 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.85 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 0.85 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 0.83 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.81 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.81 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.8 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.8 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.83 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 0.83 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.91 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.79 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.78 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.78 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.81 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.79 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 0.79 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.83 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.85 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.87 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.82 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.82 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766795 c.3426C>T synonymous_variant 0.85 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.87 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.92 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.87 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.84 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.85 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.85 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766918 c.3549C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.92 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.91 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.89 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.84 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.87 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>T synonymous_variant 0.82 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.78 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.72 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.74 rifampicin
rpoC 767206 c.3837C>A synonymous_variant 0.67 rifampicin
rpoC 767209 c.3840T>G synonymous_variant 0.64 rifampicin
rpoC 767212 c.3843G>C synonymous_variant 0.62 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.43 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpS5 779615 c.-710C>G upstream_gene_variant 0.93 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 0.73 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.57 streptomycin
rpsL 781586 c.27C>A synonymous_variant 0.7 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.67 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.69 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.66 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.71 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.69 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.69 streptomycin
rpsL 781664 c.105C>T synonymous_variant 0.66 streptomycin
rpsL 781667 c.108C>G synonymous_variant 0.66 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.76 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.74 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.73 streptomycin
rpsL 781721 c.162C>G synonymous_variant 0.75 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.8 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.84 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.88 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.85 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.88 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.91 streptomycin
rpsL 781847 c.288G>A synonymous_variant 0.91 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.85 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.83 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.85 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.83 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.83 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.84 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.82 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.8 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.79 streptomycin Uncertain significance
rplC 800209 c.-600C>T upstream_gene_variant 0.78 linezolid
rplC 800224 c.-585G>C upstream_gene_variant 0.76 linezolid
rplC 800225 c.-584T>C upstream_gene_variant 0.76 linezolid
rplC 800237 c.-572T>C upstream_gene_variant 0.79 linezolid
rplC 800244 c.-565A>G upstream_gene_variant 0.79 linezolid
rplC 800267 c.-542T>C upstream_gene_variant 0.73 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 0.68 linezolid
rplC 800278 c.-531A>G upstream_gene_variant 0.62 linezolid
rplC 800285 c.-524_-523insC upstream_gene_variant 0.5 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.68 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.68 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.67 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.67 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.68 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.77 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.74 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 0.73 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.77 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.79 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.81 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.8 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.73 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.73 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.72 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.72 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.72 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.72 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.77 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.75 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.77 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 0.85 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 0.8 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 0.8 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 0.83 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 0.8 linezolid
rplC 800817 c.9A>C synonymous_variant 0.91 linezolid
rplC 800844 c.36T>C synonymous_variant 0.91 linezolid
rplC 800865 c.57A>G synonymous_variant 0.93 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.93 linezolid
rplC 800877 c.69A>C synonymous_variant 0.93 linezolid
rplC 800907 c.99C>G synonymous_variant 0.93 linezolid
rplC 800913 c.105G>C synonymous_variant 0.88 linezolid
rplC 800916 c.108A>T synonymous_variant 0.88 linezolid
rplC 800922 c.114C>G synonymous_variant 0.88 linezolid
rplC 800934 c.126C>G synonymous_variant 0.82 linezolid
rplC 800937 c.129A>G synonymous_variant 0.82 linezolid
rplC 800946 c.138T>G synonymous_variant 0.83 linezolid
rplC 800949 c.141T>C synonymous_variant 0.81 linezolid
rplC 800955 c.147C>G synonymous_variant 0.79 linezolid
rplC 800958 c.150G>A synonymous_variant 0.75 linezolid
rplC 800970 c.162T>C synonymous_variant 0.76 linezolid Not assoc w R - Interim
rplC 800976 c.168G>A synonymous_variant 0.74 linezolid
rplC 800982 c.174C>T synonymous_variant 0.74 linezolid
rplC 800996 p.Asn63Thr missense_variant 0.65 linezolid
rplC 801009 c.201A>C synonymous_variant 0.62 linezolid
rplC 801132 c.324T>C synonymous_variant 0.43 linezolid
rplC 801144 c.336C>G synonymous_variant 0.53 linezolid
rplC 801147 c.339T>C synonymous_variant 0.59 linezolid
rplC 801153 c.345G>C synonymous_variant 0.71 linezolid
rplC 801174 c.366T>C synonymous_variant 0.82 linezolid
rplC 801201 c.393C>T synonymous_variant 0.86 linezolid
rplC 801210 c.402T>C synonymous_variant 0.85 linezolid
rplC 801216 c.408C>A synonymous_variant 0.83 linezolid
rplC 801219 c.411C>T synonymous_variant 0.78 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.78 linezolid
rplC 801246 c.438C>G synonymous_variant 0.85 linezolid
rplC 801252 c.444G>C synonymous_variant 0.82 linezolid
rplC 801267 c.459A>T synonymous_variant 0.76 linezolid
rplC 801276 c.468G>C synonymous_variant 0.71 linezolid
rplC 801297 c.489C>T synonymous_variant 0.69 linezolid Not assoc w R - Interim
rplC 801312 c.504G>C synonymous_variant 0.73 linezolid
rplC 801339 c.531T>G synonymous_variant 0.73 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.73 linezolid
rplC 801348 c.540T>G synonymous_variant 0.74 linezolid
rplC 801357 c.549T>C synonymous_variant 0.81 linezolid
rplC 801372 c.564G>A synonymous_variant 0.82 linezolid
rplC 801385 c.577C>T synonymous_variant 0.86 linezolid
rplC 801396 c.588T>C synonymous_variant 0.86 linezolid
rplC 801405 c.597T>C synonymous_variant 0.84 linezolid
rplC 801417 c.609T>C synonymous_variant 0.81 linezolid
rplC 801423 c.615G>C synonymous_variant 0.8 linezolid
rplC 801426 c.618C>G synonymous_variant 0.8 linezolid
rplC 801438 c.630T>C synonymous_variant 0.79 linezolid
rplC 801447 c.639A>G synonymous_variant 0.7 linezolid
fbiC 1303464 c.534A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303467 c.537C>A synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>A synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1303479 c.549G>A synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303591 c.661C>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 0.78 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303632 c.702T>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.83 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303768 p.Ser280Ala missense_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304055 p.Asp375Glu missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 0.48 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304059 c.1129C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304091 c.1161C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304112 c.1182G>A synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304120 p.Lys397Arg missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304124 c.1194C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304164 p.Gly412Arg missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304181 c.1251G>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304217 p.Asn429Lys missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304343 c.1413T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304355 c.1425G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304361 c.1431C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304362 p.Glu478Ser missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304376 p.Glu482Asp missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304384 p.Val485Ala missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304388 c.1458C>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304394 c.1464G>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304403 c.1473T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304415 c.1485G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304502 c.1572G>A synonymous_variant 0.55 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304511 c.1581C>T synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304598 c.1668C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304649 c.1719C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304679 c.1749G>A synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>T synonymous_variant 0.79 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304715 c.1785G>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.72 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304809 p.Ser627Glu missense_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.76 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1305001 p.Ile691Val missense_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305027 c.2097G>A synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305036 c.2106G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305051 c.2121G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1305088 p.Val720Ile missense_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 0.66 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1305162 c.2232C>T synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305165 c.2235G>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1305192 c.2262C>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>A synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305219 p.His763Gln missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>A synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
sigE 1364839 c.427T>C synonymous_variant 0.43 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 0.41 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.43 pyrazinamide
sigE 1364866 c.454_456delGCTinsAC frameshift_variant&missense_variant 0.55 pyrazinamide Uncertain significance
sigE 1364889 c.477A>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 0.65 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
sigE 1364919 c.507T>C synonymous_variant 0.53 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.54 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.5 pyrazinamide
sigE 1364955 c.543G>T synonymous_variant 0.36 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.33 pyrazinamide
Rv1258c 1406270 c.1071C>T synonymous_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406291 c.1050G>A synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406297 c.1044A>G synonymous_variant 0.43 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406314 p.His343Tyr missense_variant 0.4 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406315 p.Gln342His missense_variant 0.4 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406318 c.1021_1023delGCAinsCG frameshift_variant&synonymous_variant 0.4 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406327 c.1014G>C synonymous_variant 0.38 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406330 c.1011G>A synonymous_variant 0.38 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406333 p.Ile336Met missense_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406345 c.996T>C synonymous_variant 0.38 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406351 c.990G>C synonymous_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406553 p.Ala263Val missense_variant 0.33 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406556 p.Trp262Ser missense_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406558 c.783T>C synonymous_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406567 p.Val258Ala missense_variant 0.4 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406576 p.Gln255His missense_variant 0.33 streptomycin
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406580 p.His254Arg missense_variant 0.33 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406587 p.Thr252Ala missense_variant 0.37 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406594 c.747A>G synonymous_variant 0.39 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406597 c.744G>C synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406612 c.729G>A synonymous_variant 0.47 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407167 c.172_174delGCCinsTG frameshift_variant&missense_variant 0.64 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1407175 c.166T>C synonymous_variant 0.6 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407185 p.Met52Thr missense_variant 0.5 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407194 c.145_147delAGTinsGC frameshift_variant&synonymous_variant 0.45 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1407200 c.141G>T synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407203 c.138C>T synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407209 c.132C>G synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407218 c.123T>G synonymous_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407443 c.-103C>A upstream_gene_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407455 c.-115C>T upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407459 c.-119T>C upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407464 c.-124G>A upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407470 c.-130T>G upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407473 c.-133C>A upstream_gene_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407479 c.-139A>G upstream_gene_variant 0.44 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407480 c.-140A>T upstream_gene_variant 0.44 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407491 c.-151T>C upstream_gene_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407494 c.-154A>G upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407524 c.-184A>C upstream_gene_variant 0.33 streptomycin
isoniazid
pyrazinamide
atpE 1461025 c.-20C>T upstream_gene_variant 0.75 bedaquiline
atpE 1461041 c.-4_-2delGGAinsAAGG upstream_gene_variant 0.83 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.82 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.81 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 0.84 bedaquiline
atpE 1461161 c.117C>T synonymous_variant 0.89 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 0.9 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.85 bedaquiline
atpE 1461185 c.141G>A synonymous_variant 0.85 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.86 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.85 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.85 bedaquiline
atpE 1461230 c.186G>T synonymous_variant 0.84 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.84 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.62 bedaquiline
atpE 1461275 c.231T>C synonymous_variant 0.48 bedaquiline
rrs 1471935 n.90T>C non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471984 n.139T>A non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473517 n.-141A>G upstream_gene_variant 0.57 capreomycin
linezolid
rrl 1473519 n.-139_-138insC upstream_gene_variant 0.57 capreomycin
linezolid
rrl 1473525 n.-133C>G upstream_gene_variant 0.55 capreomycin
linezolid
rrl 1473528 n.-130_-129delGTinsA upstream_gene_variant 0.55 capreomycin
linezolid
rrl 1473541 n.-117G>A upstream_gene_variant 0.5 capreomycin
linezolid
rrl 1473542 n.-116C>T upstream_gene_variant 0.5 capreomycin
linezolid
rrl 1473571 n.-87C>T upstream_gene_variant 0.75 capreomycin
linezolid
rrl 1473592 n.-66_-65insA upstream_gene_variant 0.66 capreomycin
linezolid
rrl 1473600 n.-58A>G upstream_gene_variant 0.62 capreomycin
linezolid
rrl 1473603 n.-55C>T upstream_gene_variant 0.64 capreomycin
linezolid
rrl 1473607 n.-50_-49delGG upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473613 n.-45G>C upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473614 n.-44C>G upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473618 n.-40G>A upstream_gene_variant 0.7 capreomycin
linezolid
rrl 1473626 n.-32_-31insT upstream_gene_variant 0.78 capreomycin
linezolid
rrl 1473635 n.-23_-22insTTT upstream_gene_variant 0.78 capreomycin
linezolid
rrl 1473648 n.-9_-7delTTG upstream_gene_variant 0.82 capreomycin
linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1473981 n.324delGinsTC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474103