TB-Profiler result

Run: ERR403298
Summary

Run ID: ERR403298

Sample name:

Date: 2024-04-16T12:25:32.378410

Number of reads: 1100555

Percentage reads mapped: 32.25

Median coverage: 28.0

Strain: M.canetti;lineage4.2

Spoligotype:

Drug-resistance: MDR-TB

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.2 Euro-American None 0.11
lineage4 Euro-American None 0.08
M.canetti M.canetti None 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Thr437Ala Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.865_867delCACinsAT Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.562_564delTTGinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1144_1146delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1270_1272delCTGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1591_1593delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.706_708delGCAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1150_1152delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.316_318delGTGinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.865_867delCACinsAT Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsCG frameshift_variant&missense_variant 0.63 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.84 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303492 c.562_564delTTGinsCT frameshift_variant&synonymous_variant 0.58 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 0.78 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.7 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsAG frameshift_variant&missense_variant 0.32 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304074 c.1144_1146delGCCinsTG frameshift_variant&missense_variant 0.48 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304200 c.1270_1272delCTGinsTC frameshift_variant&missense_variant 0.52 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304521 c.1591_1593delCTGinsGA frameshift_variant&missense_variant 0.5 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.62 isoniazid Assoc w R High-level resistance
pepQ 2859552 c.865_867delCACinsAT frameshift_variant&synonymous_variant 0.63 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
fbiA 3641248 c.706_708delGCAinsAC frameshift_variant&missense_variant 0.53 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642684 c.1150_1152delTTGinsCA frameshift_variant&missense_variant 0.45 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987159 c.316_318delGTGinsAT frameshift_variant&missense_variant 0.5 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.83 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.7 ethambutol Mutation from literature
embB 4247822 p.Thr437Ala missense_variant 0.54 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 0.33 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.33 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 0.43 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 0.43 isoniazid Uncertain significance
dnaA 753 c.753C>T synonymous_variant 0.43 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.45 isoniazid
dnaA 762 c.762C>T synonymous_variant 0.43 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.48 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.58 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.58 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 0.55 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.5 isoniazid Uncertain significance
dnaA 810 c.810C>G synonymous_variant 0.48 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.52 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.58 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.69 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.7 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 849 c.849A>G synonymous_variant 0.71 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.78 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.76 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.7 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.7 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.72 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.69 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.71 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.7 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.64 isoniazid
dnaA 939 c.939C>A synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 945 c.945G>A synonymous_variant 0.56 isoniazid
dnaA 1003 c.1003C>T synonymous_variant 0.43 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.74 isoniazid
dnaA 1059 c.1059C>A synonymous_variant 0.78 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.71 isoniazid
dnaA 1083 c.1083C>T synonymous_variant 0.73 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.64 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.56 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 0.45 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 1179 c.1179G>C synonymous_variant 0.57 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.57 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 0.57 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.58 isoniazid
dnaA 1200 c.1200C>T synonymous_variant 0.6 isoniazid
dnaA 1206 c.1206G>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Thr missense_variant 0.7 isoniazid
dnaA 1222 p.Thr408Ala missense_variant 0.7 isoniazid Uncertain significance
dnaA 1245 c.1245G>C synonymous_variant 0.78 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.8 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.64 isoniazid
dnaA 1281 c.1281C>G synonymous_variant 0.62 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.62 isoniazid
dnaA 1299 c.1299G>A synonymous_variant 0.53 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.52 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 0.4 isoniazid
dnaA 1350 c.1350G>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 0.33 isoniazid
dnaA 1356 c.1356T>G synonymous_variant 0.37 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.48 isoniazid
dnaA 1374 c.1374G>T synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1375 c.1375T>C synonymous_variant 0.5 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.61 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.61 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.62 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.66 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.69 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.68 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.67 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.67 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.62 isoniazid
dnaA 1458 c.1458G>A synonymous_variant 0.58 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.58 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 1488 c.1488A>G synonymous_variant 0.48 isoniazid
dnaA 1494 c.1494C>G synonymous_variant 0.45 isoniazid
dnaA 1497 c.1497T>A synonymous_variant 0.42 isoniazid
dnaA 1498 c.1498_1500delCGCinsAG frameshift_variant&missense_variant 0.4 isoniazid Uncertain significance
gyrB 5238 c.-2T>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 5254 c.15A>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 5284 c.45G>A synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 5293 c.54C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5302 c.63A>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 5305 c.66G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 5308 c.69G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5359 c.120C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin
gyrB 5377 c.138T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5422 c.183T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5425 c.186A>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5426 p.Thr63Ala missense_variant 0.67 levofloxacin
moxifloxacin
gyrB 5431 c.192A>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 5434 c.195G>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrB 5436 p.Asn66Ser missense_variant 0.64 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 5440 c.201A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 5449 c.210T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5455 c.216T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5470 c.231C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5485 c.246C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrB 5488 c.249C>A synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5491 c.252T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 5500 c.261C>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 5502 p.Thr88Met missense_variant 0.62 levofloxacin
moxifloxacin
gyrB 5527 c.288C>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrB 5542 c.303A>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrB 5545 c.306A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 5548 c.309A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5551 c.312T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 5560 c.321C>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 5569 c.330C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrB 5572 c.333G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 5767 c.528C>T synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5771 p.Ala178Asn missense_variant 0.71 levofloxacin
moxifloxacin
gyrB 5779 c.540C>T synonymous_variant 0.75 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 5782 c.543A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 5788 c.549G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5791 c.552A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 5812 c.573C>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5815 c.576C>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5819 c.580C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5824 c.585A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 5836 c.597C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5851 c.612G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5860 c.621C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 5869 c.630C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5870 p.Glu211Gln missense_variant 0.8 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5884 c.645A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrB 6013 c.774G>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 6022 c.783G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6025 c.786A>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6037 c.798C>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6049 c.810G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6079 c.840C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrB 6085 c.846C>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.77 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.88 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.76 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6421 c.-881C>T upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6565 c.-737G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6625 c.-677G>A upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>T synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6826 c.-476G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6886 c.-416C>T upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>T upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>A upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 7151 c.1912C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7165 c.-137C>A upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7207 c.-95C>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7219 c.-83C>A upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7231 c.-71C>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7523 c.222C>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7652 c.351C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7703 c.402G>A synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7715 c.414G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 7940 c.639G>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7941 p.Glu214Thr missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7958 c.657C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.62 levofloxacin
moxifloxacin
gyrA 7970 c.669T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7973 c.672A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7988 c.687G>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7997 c.696A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8000 c.699G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8030 c.729C>A synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8042 c.741C>T synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8048 c.747C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8105 c.804G>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsGG frameshift_variant&missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.41 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8282 c.981G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 0.78 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.75 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.72 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.84 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9065 c.1764C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9197 c.1896G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9218 c.1917C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.91 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9476 c.2175G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9585 c.2284T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 0.77 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9722 c.2421C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>A synonymous_variant 0.69 levofloxacin
moxifloxacin
Rv0010c 13891 c.-333G>C upstream_gene_variant 0.58 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.62 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.62 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.62 isoniazid
fgd1 490781 c.-2T>G upstream_gene_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 490782 c.-1G>A upstream_gene_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.79 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 490809 c.27A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490853 p.Ala24Gly missense_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 490863 c.81C>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490945 c.163C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 490984 p.Leu68Val missense_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491154 p.Glu124Asp missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fgd1 491265 c.483G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.7 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491298 c.516C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491331 c.549G>A synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.5 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>A synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
mshA 574688 c.-660G>C upstream_gene_variant 0.35 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.33 ethionamide
isoniazid
mshA 574703 c.-645C>T upstream_gene_variant 0.32 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 0.33 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 0.35 ethionamide
isoniazid
mshA 574721 c.-627C>G upstream_gene_variant 0.35 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 0.4 ethionamide
isoniazid
mshA 574738 c.-610_-609delGTinsAC upstream_gene_variant 0.38 ethionamide
isoniazid
mshA 574763 c.-585T>C upstream_gene_variant 0.4 ethionamide
isoniazid Uncertain significance
mshA 575506 c.159C>T synonymous_variant 0.53 ethionamide
isoniazid
mshA 575512 c.165A>G synonymous_variant 0.6 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.61 ethionamide
isoniazid
mshA 575530 c.183C>G synonymous_variant 0.67 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.68 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.71 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575548 c.201C>A synonymous_variant 0.77 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.79 ethionamide
isoniazid
mshA 575586 p.Ala80Gly missense_variant 0.77 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575593 c.246G>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 0.75 ethionamide
isoniazid
mshA 575629 c.282A>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 575633 c.286_288delGCAinsAG frameshift_variant&missense_variant 0.76 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575652 p.Arg102Gln missense_variant 0.76 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575662 c.315C>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.76 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575686 c.339G>A synonymous_variant 0.79 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575692 c.345G>A synonymous_variant 0.82 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.78 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.79 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 0.81 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.77 ethionamide
isoniazid
mshA 575824 c.477T>C synonymous_variant 0.76 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.8 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 0.78 ethionamide
isoniazid
mshA 575878 c.531A>T synonymous_variant 0.76 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.77 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.73 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 0.68 ethionamide
isoniazid Not assoc w R - Interim
mshA 575908 c.561A>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.81 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 0.83 ethionamide
isoniazid
mshA 576460 c.1113C>G synonymous_variant 0.39 ethionamide
isoniazid
mshA 576463 c.1116G>T synonymous_variant 0.37 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 576469 c.1122G>C synonymous_variant 0.43 ethionamide
isoniazid
mshA 576481 c.1134C>G synonymous_variant 0.47 ethionamide
isoniazid
mshA 576490 c.1143G>T synonymous_variant 0.53 ethionamide
isoniazid
mshA 576511 c.1164C>G synonymous_variant 0.47 ethionamide
isoniazid
mshA 576517 c.1170G>A synonymous_variant 0.39 ethionamide
isoniazid
mshA 576523 c.1176G>A synonymous_variant 0.39 ethionamide
isoniazid
ccsA 619624 c.-267C>T upstream_gene_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619648 c.-243C>G upstream_gene_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 619681 c.-210G>A upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194A>C upstream_gene_variant 0.68 capreomycin
amikacin
kanamycin
ccsA 619744 c.-147A>G upstream_gene_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620214 c.324C>A synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620314 c.424C>T synonymous_variant 0.84 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620325 c.435G>T synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620404 c.514C>T synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.84 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620479 c.589_591delCTTinsTG frameshift_variant&missense_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620487 c.597C>G synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>C synonymous_variant 0.61 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620571 c.681A>G synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>A synonymous_variant 0.79 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620622 c.732G>C synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>T synonymous_variant 0.76 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 0.76 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.68 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>T synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 620760 c.870C>G synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.69 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620829 c.939G>T synonymous_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620838 c.948C>T synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620839 c.949C>T synonymous_variant 0.55 capreomycin
amikacin
kanamycin
Rv0565c 656067 c.1404C>T synonymous_variant 0.56 ethionamide
Rv0565c 656073 p.Leu466Phe missense_variant 0.71 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 0.73 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 0.76 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.76 ethionamide
Rv0565c 656103 c.1368G>A synonymous_variant 0.74 ethionamide
Rv0565c 656112 c.1359C>A synonymous_variant 0.7 ethionamide
Rv0565c 656116 p.Lys452Arg missense_variant 0.67 ethionamide
Rv0565c 656129 p.Tyr448His missense_variant 0.59 ethionamide
Rv0565c 656131 p.Pro447Leu missense_variant 0.56 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 0.56 ethionamide
Rv0565c 656136 c.1335G>C synonymous_variant 0.6 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 0.56 ethionamide
Rv0565c 656277 c.1194C>T synonymous_variant 0.47 ethionamide
Rv0565c 656282 c.1189C>T synonymous_variant 0.47 ethionamide Not assoc w R - Interim
Rv0565c 656295 c.1176C>T synonymous_variant 0.45 ethionamide
Rv0565c 656301 c.1170C>T synonymous_variant 0.45 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.45 ethionamide
Rv0565c 656922 c.547_549delATCinsGG frameshift_variant&missense_variant 0.55 ethionamide Uncertain significance
Rv0565c 656936 p.Thr179Ala missense_variant 0.46 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.43 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 0.43 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 0.43 ethionamide
Rv0565c 656964 c.507C>G synonymous_variant 0.5 ethionamide
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657171 c.300T>C synonymous_variant 0.47 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.55 ethionamide
Rv0565c 657196 p.Asp92Thr missense_variant 0.55 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 0.62 ethionamide
Rv0565c 657207 c.264G>A synonymous_variant 0.68 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 0.75 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.7 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.69 ethionamide Uncertain significance
Rv0565c 657243 c.228C>A synonymous_variant 0.69 ethionamide
Rv0565c 657267 c.202_204delTCGinsAGC synonymous_variant 0.77 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.77 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.75 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.74 ethionamide
Rv0565c 657340 p.Ala44Glu missense_variant 0.61 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 0.53 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.5 ethionamide
Rv0565c 657587 c.-117C>T upstream_gene_variant 0.57 ethionamide
Rv0565c 657590 c.-120G>C upstream_gene_variant 0.57 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.59 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 0.75 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.75 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsAT upstream_gene_variant 0.76 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.86 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.84 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 0.82 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.82 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.89 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.76 ethionamide
hadA 731687 c.-243G>C upstream_gene_variant 0.39 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 0.39 isoniazid
hadA 731693 c.-237_-236insGTTTGACACCAGAT upstream_gene_variant 0.38 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.43 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.57 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.62 isoniazid
hadA 731738 c.-192G>T upstream_gene_variant 0.81 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.81 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.84 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.87 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 0.86 isoniazid
hadA 731837 c.-93C>T upstream_gene_variant 0.81 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.79 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.7 isoniazid
hadA 731858 c.-72G>A upstream_gene_variant 0.68 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.56 isoniazid
hadA 732247 c.318C>T synonymous_variant 0.65 isoniazid
hadA 732250 c.321C>G synonymous_variant 0.72 isoniazid
hadA 732263 p.Val112Met missense_variant 0.72 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.77 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.75 isoniazid
hadA 732322 p.Glu131Asp missense_variant 0.8 isoniazid
hadA 732329 c.400_402delCTCinsAT frameshift_variant&missense_variant 0.82 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 0.85 isoniazid
hadA 732361 c.432C>T synonymous_variant 0.89 isoniazid
hadA 732376 c.447T>C synonymous_variant 0.82 isoniazid
hadA 732378 c.449_450insGGA disruptive_inframe_insertion 0.84 isoniazid
hadA 732381 p.Glu151Val missense_variant 0.86 isoniazid
hadA 732391 c.462T>A synonymous_variant 0.91 isoniazid
nusG 734352 c.99T>C synonymous_variant 0.64 rifampicin
nusG 734361 c.108C>T synonymous_variant 0.72 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.78 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.78 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.85 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.88 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.88 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.84 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.82 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.85 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.83 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.8 rifampicin
nusG 734616 c.363C>A synonymous_variant 0.8 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.78 rifampicin
nusG 734631 c.378G>A synonymous_variant 0.74 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.73 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.74 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.75 rifampicin
nusG 734661 c.408A>C synonymous_variant 0.76 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.76 rifampicin
nusG 734670 c.417G>A synonymous_variant 0.81 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.8 rifampicin
nusG 734680 p.Ala143Ser missense_variant 0.79 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.86 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.83 rifampicin
nusG 734712 c.459G>C synonymous_variant 0.83 rifampicin
nusG 734718 c.465G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 0.85 rifampicin
nusG 734722 p.Thr157Ala missense_variant 0.85 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.88 rifampicin
nusG 734733 c.480T>A synonymous_variant 0.91 rifampicin
nusG 734736 c.483C>G synonymous_variant 0.88 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.81 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.81 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.79 rifampicin
nusG 734769 c.516G>A synonymous_variant 0.79 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.8 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.79 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.8 rifampicin
nusG 734793 c.540C>T synonymous_variant 0.81 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.85 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.86 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.85 rifampicin
nusG 734874 c.621G>A synonymous_variant 0.84 rifampicin
nusG 734880 c.627C>T synonymous_variant 0.85 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.8 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.7 rifampicin
nusG 734928 c.675A>G synonymous_variant 0.48 rifampicin
rpoB 759583 c.-224T>G upstream_gene_variant 0.67 rifampicin
rpoB 759587 c.-220T>A upstream_gene_variant 0.7 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 0.82 rifampicin
rpoB 759635 c.-172C>T upstream_gene_variant 0.85 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.85 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.85 rifampicin Uncertain significance
rpoB 759661 c.-146G>C upstream_gene_variant 0.83 rifampicin
rpoB 759670 c.-137C>T upstream_gene_variant 0.83 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.86 rifampicin
rpoB 759676 c.-131A>G upstream_gene_variant 0.85 rifampicin
rpoB 759692 c.-115T>C upstream_gene_variant 0.85 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 0.81 rifampicin
rpoB 759914 c.108T>C synonymous_variant 0.79 rifampicin
rpoB 759920 c.114G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 759929 c.123A>G synonymous_variant 0.82 rifampicin
rpoB 759932 c.126T>G synonymous_variant 0.74 rifampicin
rpoB 759944 c.138A>G synonymous_variant 0.7 rifampicin
rpoB 759945 c.139_141delCTCinsTG frameshift_variant&missense_variant 0.7 rifampicin
rpoB 759956 c.150C>G synonymous_variant 0.67 rifampicin
rpoB 759965 c.159T>C synonymous_variant 0.74 rifampicin
rpoB 759989 c.183G>C synonymous_variant 0.53 rifampicin
rpoB 759991 p.Pro62Gln missense_variant 0.5 rifampicin
rpoB 760059 p.Tyr85Asp missense_variant 0.64 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.68 rifampicin
rpoB 760070 c.264T>A synonymous_variant 0.68 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.82 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.8 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.85 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 0.87 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.84 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 0.86 rifampicin
rpoB 760196 c.390C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.89 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.88 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.86 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.82 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.76 rifampicin
rpoB 760409 c.603C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 0.75 rifampicin
rpoB 760415 c.609C>G synonymous_variant 0.75 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 0.8 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 0.79 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.8 rifampicin
rpoB 760528 p.Gln241Arg missense_variant 0.79 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.79 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.92 rifampicin Uncertain significance
rpoB 760577 c.771G>A synonymous_variant 0.93 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.85 rifampicin
rpoB 760604 c.798G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 0.8 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>A synonymous_variant 0.81 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760664 c.858G>C synonymous_variant 0.75 rifampicin
rpoB 760670 c.864G>C synonymous_variant 0.73 rifampicin
rpoB 760673 c.867G>A synonymous_variant 0.73 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.71 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760727 c.921C>A synonymous_variant 0.69 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760805 c.999G>C synonymous_variant 0.68 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.76 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.87 rifampicin
rpoB 760859 c.1053T>G synonymous_variant 0.88 rifampicin
rpoB 760868 c.1062C>G synonymous_variant 0.91 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.88 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.88 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.88 rifampicin
rpoB 760994 c.1188G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.85 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>A synonymous_variant 0.8 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761066 c.1260G>C synonymous_variant 0.85 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 0.83 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.84 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.85 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.81 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 0.81 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.82 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.82 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 0.81 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.81 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761408 c.1602G>C synonymous_variant 0.61 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 0.69 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.75 rifampicin
rpoB 761438 c.1632G>T synonymous_variant 0.77 rifampicin
rpoB 761441 p.Asp545Glu missense_variant 0.8 rifampicin Uncertain significance
rpoB 761444 c.1638T>C synonymous_variant 0.8 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.8 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 0.8 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.84 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.82 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 0.85 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 0.83 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.87 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.86 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 0.85 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.85 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.89 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.81 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.9 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.88 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.82 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 0.8 rifampicin
rpoB 761735 c.1929C>G synonymous_variant 0.53 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.61 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.63 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.59 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.57 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.52 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.62 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.67 rifampicin
rpoB 761822 c.2016C>G synonymous_variant 0.67 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.65 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.62 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 0.59 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 0.59 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.62 rifampicin
rpoB 761876 c.2070C>A synonymous_variant 0.73 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.8 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.83 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.71 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.71 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 0.71 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.73 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.72 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 0.7 rifampicin
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 0.7 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762071 c.2265C>T synonymous_variant 0.77 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.86 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 0.85 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.87 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.91 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 0.93 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 0.94 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.89 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.88 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.88 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>G synonymous_variant 0.86 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.72 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.71 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.75 rifampicin
rpoB 762369 c.2563_2565delTTGinsCT frameshift_variant&synonymous_variant 0.65 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.7 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.8 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.72 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.74 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.74 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.78 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.84 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 0.76 rifampicin
rpoB 762489 p.Val895Gln missense_variant 0.76 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.79 rifampicin
rpoC 762518 c.-852C>G upstream_gene_variant 0.78 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.73 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.71 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.71 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.8 rifampicin
rpoC 762557 c.-813G>C upstream_gene_variant 0.78 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.72 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.72 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.71 rifampicin
rpoC 762599 c.-771T>A upstream_gene_variant 0.71 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 0.7 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 0.76 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762813 c.3007_3009delATGinsGC frameshift_variant&missense_variant 0.76 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 0.8 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>T upstream_gene_variant 0.78 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.8 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 0.81 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.86 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.84 rifampicin
rpoB 763193 c.3387C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.71 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.67 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.71 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.53 rifampicin Uncertain significance
rpoC 763375 c.6C>A synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.85 rifampicin
rpoC 763430 c.61A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763435 c.66A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 0.9 rifampicin
rpoC 763561 c.192G>A synonymous_variant 0.93 rifampicin
rpoC 763600 c.231C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.96 rifampicin
rpoC 763618 c.249C>A synonymous_variant 0.94 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 0.92 rifampicin
rpoC 763639 c.270G>A synonymous_variant 0.95 rifampicin
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 763666 c.297G>A synonymous_variant 0.92 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.87 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.87 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.86 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.87 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.89 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.87 rifampicin
rpoC 763771 c.402C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.83 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.86 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.84 rifampicin
rpoC 763819 c.450G>C synonymous_variant 0.79 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.67 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.6 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.62 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.62 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.65 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.74 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.72 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.79 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.8 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.76 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.72 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.68 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.73 rifampicin
rpoC 764101 c.732C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.74 rifampicin
rpoC 764119 c.750G>A synonymous_variant 0.79 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.78 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 0.8 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.76 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.75 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.78 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.76 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.72 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.76 rifampicin
rpoC 764272 c.903G>T synonymous_variant 0.78 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.82 rifampicin
rpoC 764317 c.948C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>T synonymous_variant 0.81 rifampicin
rpoC 764347 c.978G>C synonymous_variant 0.85 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.68 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>A synonymous_variant 0.66 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.57 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.52 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.52 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.53 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.56 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.58 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.64 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>A synonymous_variant 0.65 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 0.64 rifampicin
rpoC 764536 c.1167G>A synonymous_variant 0.65 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.61 rifampicin
rpoC 764587 c.1218C>G synonymous_variant 0.76 rifampicin
rpoC 764648 c.1279C>A synonymous_variant 0.86 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 0.84 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.86 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764674 c.1305G>A synonymous_variant 0.84 rifampicin
rpoC 764681 c.1312C>T synonymous_variant 0.85 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.81 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>C synonymous_variant 0.82 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 0.83 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.81 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.8 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 0.8 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.72 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 0.81 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.8 rifampicin
rpoC 764918 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 0.77 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.79 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765067 c.1698G>C synonymous_variant 0.47 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.45 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 0.47 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 0.5 rifampicin
rpoC 765088 c.1719G>C synonymous_variant 0.53 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765100 c.1731G>C synonymous_variant 0.53 rifampicin
rpoC 765103 c.1734G>A synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765115 c.1746G>A synonymous_variant 0.5 rifampicin
rpoC 765122 c.1753C>T synonymous_variant 0.5 rifampicin
rpoC 765287 c.1918C>T synonymous_variant 0.38 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.4 rifampicin
rpoC 765296 c.1927_1929delCCGinsTT frameshift_variant&missense_variant 0.35 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.35 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>G synonymous_variant 0.38 rifampicin
rpoC 765326 p.His653Thr missense_variant 0.35 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.4 rifampicin Uncertain significance
rpoC 765340 p.Gln657His missense_variant 0.53 rifampicin
rpoC 765349 p.Asp660Glu missense_variant 0.55 rifampicin
rpoC 765350 c.1981_1983delGCGinsCC frameshift_variant&missense_variant 0.53 rifampicin
rpoC 765358 p.Met663Ile missense_variant 0.63 rifampicin Uncertain significance
rpoC 765364 p.Glu665Asp missense_variant 0.63 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 0.68 rifampicin
rpoC 765376 c.2007C>G synonymous_variant 0.73 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.78 rifampicin Uncertain significance
rpoC 765395 c.2026C>T synonymous_variant 0.77 rifampicin
rpoC 765405 p.Leu679Pro missense_variant 0.78 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 0.85 rifampicin
rpoC 765430 c.2061G>A synonymous_variant 0.85 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.8 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.8 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 0.8 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765526 c.2157C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>A synonymous_variant 0.78 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.81 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.79 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.79 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.78 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 0.81 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 0.82 rifampicin
rpoC 765610 c.2241C>T synonymous_variant 0.73 rifampicin
rpoC 765612 p.His748Arg missense_variant 0.73 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.76 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765676 c.2307G>A synonymous_variant 0.85 rifampicin
rpoC 765688 c.2319G>C synonymous_variant 0.84 rifampicin
rpoC 765689 c.2320C>T synonymous_variant 0.84 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 0.87 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 0.82 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 0.74 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 0.72 rifampicin
rpoC 765757 c.2388C>T synonymous_variant 0.73 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.72 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.72 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.72 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.73 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>A synonymous_variant 0.8 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.86 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.86 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.88 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 0.85 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 0.8 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.76 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 0.76 rifampicin
rpoC 766070 c.2701C>T synonymous_variant 0.67 rifampicin Not assoc w R
rpoC 766082 p.Ala905Gln missense_variant 0.44 rifampicin
rpoC 766249 c.2880C>A synonymous_variant 0.55 rifampicin
rpoC 766255 c.2886G>T synonymous_variant 0.54 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.69 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.8 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.84 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 0.71 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 766306 c.2937C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.77 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.75 rifampicin
rpoC 766324 c.2955C>T synonymous_variant 0.79 rifampicin
rpoC 766351 c.2982C>G synonymous_variant 0.76 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 0.74 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.71 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.68 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.75 rifampicin
rpoC 766397 c.3028C>T synonymous_variant 0.76 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766417 c.3048C>T synonymous_variant 0.75 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.73 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.87 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.86 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.83 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766519 c.3150C>A synonymous_variant 0.86 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.85 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.86 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.84 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.85 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 0.85 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 0.83 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.81 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.81 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.8 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.8 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.83 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 0.83 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.91 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.79 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.78 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.78 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.81 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.79 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 0.79 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.83 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.85 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.87 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.82 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.82 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766795 c.3426C>T synonymous_variant 0.85 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.87 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.92 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.87 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.84 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.85 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.85 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766918 c.3549C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.92 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.91 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.89 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.84 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.87 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>T synonymous_variant 0.82 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.78 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.72 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.74 rifampicin
rpoC 767206 c.3837C>A synonymous_variant 0.67 rifampicin
rpoC 767209 c.3840T>G synonymous_variant 0.64 rifampicin
rpoC 767212 c.3843G>C synonymous_variant 0.62 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.43 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpS5 779615 c.-710C>G upstream_gene_variant 0.93 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 0.73 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.57 streptomycin
rpsL 781586 c.27C>A synonymous_variant 0.7 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.67 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.69 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.66 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.71 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.69 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.69 streptomycin
rpsL 781664 c.105C>T synonymous_variant 0.66 streptomycin
rpsL 781667 c.108C>G synonymous_variant 0.66 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.76 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.74 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.73 streptomycin
rpsL 781721 c.162C>G synonymous_variant 0.75 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.8 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.84 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.88 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.85 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.88 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.91 streptomycin
rpsL 781847 c.288G>A synonymous_variant 0.91 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.85 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.83 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.85 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.83 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.83 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.84 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.82 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.8 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.79 streptomycin Uncertain significance
rplC 800209 c.-600C>T upstream_gene_variant 0.78 linezolid
rplC 800224 c.-585G>C upstream_gene_variant 0.76 linezolid
rplC 800225 c.-584T>C upstream_gene_variant 0.76 linezolid
rplC 800237 c.-572T>C upstream_gene_variant 0.79 linezolid
rplC 800244 c.-565A>G upstream_gene_variant 0.79 linezolid
rplC 800267 c.-542T>C upstream_gene_variant 0.73 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 0.68 linezolid
rplC 800278 c.-531A>G upstream_gene_variant 0.62 linezolid
rplC 800285 c.-524_-523insC upstream_gene_variant 0.5 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.68 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.68 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.67 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.67 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.68 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.77 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.74 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 0.73 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.77 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.79 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.81 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.8 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.73 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.73 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.72 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.72 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.72 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.72 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.77 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.75 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.77 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 0.85 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 0.8 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 0.8 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 0.83 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 0.8 linezolid
rplC 800817 c.9A>C synonymous_variant 0.91 linezolid
rplC 800844 c.36T>C synonymous_variant 0.91 linezolid
rplC 800865 c.57A>G synonymous_variant 0.93 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.93 linezolid
rplC 800877 c.69A>C synonymous_variant 0.93 linezolid
rplC 800907 c.99C>G synonymous_variant 0.93 linezolid
rplC 800913 c.105G>C synonymous_variant 0.88 linezolid
rplC 800916 c.108A>T synonymous_variant 0.88 linezolid
rplC 800922 c.114C>G synonymous_variant 0.88 linezolid
rplC 800934 c.126C>G synonymous_variant 0.82 linezolid
rplC 800937 c.129A>G synonymous_variant 0.82 linezolid
rplC 800946 c.138T>G synonymous_variant 0.83 linezolid
rplC 800949 c.141T>C synonymous_variant 0.81 linezolid
rplC 800955 c.147C>G synonymous_variant 0.79 linezolid
rplC 800958 c.150G>A synonymous_variant 0.75 linezolid
rplC 800970 c.162T>C synonymous_variant 0.76 linezolid Not assoc w R - Interim
rplC 800976 c.168G>A synonymous_variant 0.74 linezolid
rplC 800982 c.174C>T synonymous_variant 0.74 linezolid
rplC 800996 p.Asn63Thr missense_variant 0.65 linezolid
rplC 801009 c.201A>C synonymous_variant 0.62 linezolid
rplC 801132 c.324T>C synonymous_variant 0.43 linezolid
rplC 801144 c.336C>G synonymous_variant 0.53 linezolid
rplC 801147 c.339T>C synonymous_variant 0.59 linezolid
rplC 801153 c.345G>C synonymous_variant 0.71 linezolid
rplC 801174 c.366T>C synonymous_variant 0.82 linezolid
rplC 801201 c.393C>T synonymous_variant 0.86 linezolid
rplC 801210 c.402T>C synonymous_variant 0.85 linezolid
rplC 801216 c.408C>A synonymous_variant 0.83 linezolid
rplC 801219 c.411C>T synonymous_variant 0.78 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.78 linezolid
rplC 801246 c.438C>G synonymous_variant 0.85 linezolid
rplC 801252 c.444G>C synonymous_variant 0.82 linezolid
rplC 801267 c.459A>T synonymous_variant 0.76 linezolid
rplC 801276 c.468G>C synonymous_variant 0.71 linezolid
rplC 801297 c.489C>T synonymous_variant 0.69 linezolid Not assoc w R - Interim
rplC 801312 c.504G>C synonymous_variant 0.73 linezolid
rplC 801339 c.531T>G synonymous_variant 0.73 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.73 linezolid
rplC 801348 c.540T>G synonymous_variant 0.74 linezolid
rplC 801357 c.549T>C synonymous_variant 0.81 linezolid
rplC 801372 c.564G>A synonymous_variant 0.82 linezolid
rplC 801385 c.577C>T synonymous_variant 0.86 linezolid
rplC 801396 c.588T>C synonymous_variant 0.86 linezolid
rplC 801405 c.597T>C synonymous_variant 0.84 linezolid
rplC 801417 c.609T>C synonymous_variant 0.81 linezolid
rplC 801423 c.615G>C synonymous_variant 0.8 linezolid
rplC 801426 c.618C>G synonymous_variant 0.8 linezolid
rplC 801438 c.630T>C synonymous_variant 0.79 linezolid
rplC 801447 c.639A>G synonymous_variant 0.7 linezolid
fbiC 1303464 c.534A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303467 c.537C>A synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>A synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1303479 c.549G>A synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303591 c.661C>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 0.78 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303632 c.702T>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.83 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303768 p.Ser280Ala missense_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304055 p.Asp375Glu missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 0.48 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304059 c.1129C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304091 c.1161C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304112 c.1182G>A synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304120 p.Lys397Arg missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304124 c.1194C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304164 p.Gly412Arg missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304181 c.1251G>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304217 p.Asn429Lys missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304343 c.1413T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304355 c.1425G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304361 c.1431C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304362 p.Glu478Ser missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304376 p.Glu482Asp missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304384 p.Val485Ala missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304388 c.1458C>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304394 c.1464G>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304403 c.1473T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304415 c.1485G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304502 c.1572G>A synonymous_variant 0.55 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304511 c.1581C>T synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304598 c.1668C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304649 c.1719C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304679 c.1749G>A synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>T synonymous_variant 0.79 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304715 c.1785G>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.72 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304809 p.Ser627Glu missense_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.76 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1305001 p.Ile691Val missense_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305027 c.2097G>A synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305036 c.2106G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305051 c.2121G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1305088 p.Val720Ile missense_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 0.66 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1305162 c.2232C>T synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305165 c.2235G>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1305192 c.2262C>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>A synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305219 p.His763Gln missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>A synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
sigE 1364839 c.427T>C synonymous_variant 0.43 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 0.41 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.43 pyrazinamide
sigE 1364866 c.454_456delGCTinsAC frameshift_variant&missense_variant 0.55 pyrazinamide Uncertain significance
sigE 1364889 c.477A>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 0.65 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
sigE 1364919 c.507T>C synonymous_variant 0.53 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.54 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.5 pyrazinamide
sigE 1364955 c.543G>T synonymous_variant 0.36 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.33 pyrazinamide
Rv1258c 1406270 c.1071C>T synonymous_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406291 c.1050G>A synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406297 c.1044A>G synonymous_variant 0.43 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406314 p.His343Tyr missense_variant 0.4 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406315 p.Gln342His missense_variant 0.4 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406318 c.1021_1023delGCAinsCG frameshift_variant&synonymous_variant 0.4 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406327 c.1014G>C synonymous_variant 0.38 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406330 c.1011G>A synonymous_variant 0.38 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406333 p.Ile336Met missense_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406345 c.996T>C synonymous_variant 0.38 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406351 c.990G>C synonymous_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406553 p.Ala263Val missense_variant 0.33 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406556 p.Trp262Ser missense_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406558 c.783T>C synonymous_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406567 p.Val258Ala missense_variant 0.4 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406576 p.Gln255His missense_variant 0.33 streptomycin
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406580 p.His254Arg missense_variant 0.33 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406587 p.Thr252Ala missense_variant 0.37 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406594 c.747A>G synonymous_variant 0.39 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406597 c.744G>C synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406612 c.729G>A synonymous_variant 0.47 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407167 c.172_174delGCCinsTG frameshift_variant&missense_variant 0.64 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1407175 c.166T>C synonymous_variant 0.6 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407185 p.Met52Thr missense_variant 0.5 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407194 c.145_147delAGTinsGC frameshift_variant&synonymous_variant 0.45 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1407200 c.141G>T synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407203 c.138C>T synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407209 c.132C>G synonymous_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407218 c.123T>G synonymous_variant 0.35 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407443 c.-103C>A upstream_gene_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407455 c.-115C>T upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407459 c.-119T>C upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407464 c.-124G>A upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407470 c.-130T>G upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407473 c.-133C>A upstream_gene_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407479 c.-139A>G upstream_gene_variant 0.44 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407480 c.-140A>T upstream_gene_variant 0.44 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407491 c.-151T>C upstream_gene_variant 0.42 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407494 c.-154A>G upstream_gene_variant 0.41 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407524 c.-184A>C upstream_gene_variant 0.33 streptomycin
isoniazid
pyrazinamide
atpE 1461025 c.-20C>T upstream_gene_variant 0.75 bedaquiline
atpE 1461041 c.-4_-2delGGAinsAAGG upstream_gene_variant 0.83 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.82 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.81 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 0.84 bedaquiline
atpE 1461161 c.117C>T synonymous_variant 0.89 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 0.9 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.85 bedaquiline
atpE 1461185 c.141G>A synonymous_variant 0.85 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.86 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.85 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.85 bedaquiline
atpE 1461230 c.186G>T synonymous_variant 0.84 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.84 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.62 bedaquiline
atpE 1461275 c.231T>C synonymous_variant 0.48 bedaquiline
rrs 1471935 n.90T>C non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471984 n.139T>A non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473517 n.-141A>G upstream_gene_variant 0.57 capreomycin
linezolid
rrl 1473519 n.-139_-138insC upstream_gene_variant 0.57 capreomycin
linezolid
rrl 1473525 n.-133C>G upstream_gene_variant 0.55 capreomycin
linezolid
rrl 1473528 n.-130_-129delGTinsA upstream_gene_variant 0.55 capreomycin
linezolid
rrl 1473541 n.-117G>A upstream_gene_variant 0.5 capreomycin
linezolid
rrl 1473542 n.-116C>T upstream_gene_variant 0.5 capreomycin
linezolid
rrl 1473571 n.-87C>T upstream_gene_variant 0.75 capreomycin
linezolid
rrl 1473592 n.-66_-65insA upstream_gene_variant 0.66 capreomycin
linezolid
rrl 1473600 n.-58A>G upstream_gene_variant 0.62 capreomycin
linezolid
rrl 1473603 n.-55C>T upstream_gene_variant 0.64 capreomycin
linezolid
rrl 1473607 n.-50_-49delGG upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473613 n.-45G>C upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473614 n.-44C>G upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473618 n.-40G>A upstream_gene_variant 0.7 capreomycin
linezolid
rrl 1473626 n.-32_-31insT upstream_gene_variant 0.78 capreomycin
linezolid
rrl 1473635 n.-23_-22insTTT upstream_gene_variant 0.78 capreomycin
linezolid
rrl 1473648 n.-9_-7delTTG upstream_gene_variant 0.82 capreomycin
linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1473981 n.324delGinsTC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474285 n.630_631delTC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474293 n.636_649delTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474419 n.762A>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474425 n.768_770delATAinsG non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474430 n.773C>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475273 n.1616T>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475290 n.1633A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.81 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.82 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1476759 n.3102T>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
inhA 1673517 c.-685G>A upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1673568 c.-634C>G upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673589 c.-613A>C upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.74 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.74 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.77 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 0.76 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 0.79 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.57 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.55 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.55 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.53 ethionamide
isoniazid
inhA 1673679 c.-523T>G upstream_gene_variant 0.66 ethionamide
isoniazid
inhA 1673682 c.-520G>C upstream_gene_variant 0.67 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.69 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsGC frameshift_variant&missense_variant 0.68 ethionamide
isoniazid
inhA 1673715 c.-487C>T upstream_gene_variant 0.66 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 0.64 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.65 ethionamide
isoniazid
inhA 1673736 c.-466G>A upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673745 c.-457G>A upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.69 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.65 ethionamide
isoniazid
fabG1 1673767 p.Asn110Asp missense_variant 0.73 ethionamide
isoniazid
inhA 1673871 c.-331C>T upstream_gene_variant 0.59 ethionamide
isoniazid
inhA 1673916 c.-286A>T upstream_gene_variant 0.69 ethionamide
isoniazid
inhA 1673919 c.-283G>C upstream_gene_variant 0.69 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.69 ethionamide
isoniazid
inhA 1673925 c.-277C>G upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673946 c.-256C>A upstream_gene_variant 0.69 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1673960 p.Ala174Val missense_variant 0.69 ethionamide
isoniazid
inhA 1673970 c.-232C>G upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 0.69 ethionamide
isoniazid
inhA 1673982 c.-220G>C upstream_gene_variant 0.65 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 0.59 ethionamide
isoniazid
inhA 1673991 c.-211C>G upstream_gene_variant 0.61 ethionamide
isoniazid
inhA 1674015 c.-187C>A upstream_gene_variant 0.74 ethionamide
isoniazid
inhA 1674018 c.-184G>C upstream_gene_variant 0.72 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.72 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.73 ethionamide
isoniazid
fabG1 1674037 p.Gln200Glu missense_variant 0.72 ethionamide
isoniazid
inhA 1674045 c.-157G>A upstream_gene_variant 0.74 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.77 ethionamide
isoniazid
fabG1 1674079 c.640_642delCCCinsGT frameshift_variant&missense_variant 0.76 ethionamide
isoniazid
inhA 1674105 c.-97C>T upstream_gene_variant 0.75 ethionamide
isoniazid
inhA 1674108 c.-94C>T upstream_gene_variant 0.7 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674111 c.-91G>A upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 0.68 ethionamide
isoniazid
inhA 1674117 c.-85C>G upstream_gene_variant 0.68 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 0.68 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 0.63 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.68 ethionamide
isoniazid
inhA 1674156 c.-46C>T upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 0.38 ethionamide
isoniazid
inhA 1674273 c.72C>T synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674279 c.78A>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674285 c.84A>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674315 c.114C>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674321 c.120G>T synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674331 c.130C>T synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674348 c.147C>G synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674361 c.160_162delCTGinsTA frameshift_variant&stop_gained 0.54 ethionamide
isoniazid
inhA 1674368 p.Ala56Glu missense_variant 0.54 ethionamide
isoniazid
inhA 1674375 c.174C>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674384 c.183C>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674387 c.186A>G synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674472 p.Val91Leu missense_variant 0.53 ethionamide
isoniazid
inhA 1674477 c.276G>C synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.52 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.52 ethionamide
isoniazid
inhA 1674501 c.300G>A synonymous_variant 0.52 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 0.52 ethionamide
isoniazid
inhA 1674513 c.312C>G synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.62 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674561 c.360C>T synonymous_variant 0.6 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674675 c.474C>T synonymous_variant 0.85 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674703 c.502T>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.76 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674762 c.561T>C synonymous_variant 0.77 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674799 p.Ser200Ala missense_variant 0.87 ethionamide
isoniazid
inhA 1674804 c.603G>A synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674852 c.651G>A synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674882 c.681G>C synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674885 c.684C>T synonymous_variant 0.78 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674903 c.702T>C synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.81 ethionamide
isoniazid
inhA 1674912 c.711G>C synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674927 c.726G>C synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674933 c.732G>A synonymous_variant 0.64 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674942 c.741T>G synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674945 p.Asp248Glu missense_variant 0.65 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674966 c.765T>G synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674977 p.Tyr259Phe missense_variant 0.8 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674999 c.798C>T synonymous_variant 0.85 ethionamide
isoniazid
inhA 1675002 c.801A>G synonymous_variant 0.85 ethionamide
isoniazid
rpsA 1833256 c.-286C>G upstream_gene_variant 0.82 pyrazinamide
rpsA 1833262 c.-280T>A upstream_gene_variant 0.86 pyrazinamide
rpsA 1833271 c.-271G>A upstream_gene_variant 0.78 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 0.71 pyrazinamide
rpsA 1833295 c.-247C>G upstream_gene_variant 0.65 pyrazinamide
rpsA 1833298 c.-244G>A upstream_gene_variant 0.64 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.56 pyrazinamide
rpsA 1833317 c.-225_-223delCTCinsTG upstream_gene_variant 0.5 pyrazinamide
rpsA 1833325 c.-217C>T upstream_gene_variant 0.52 pyrazinamide
rpsA 1833334 c.-208G>A upstream_gene_variant 0.44 pyrazinamide
rpsA 1833515 c.-27_-26delCAinsG upstream_gene_variant 0.62 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.85 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 0.85 pyrazinamide
rpsA 1833593 c.52_54delTCTinsAC frameshift_variant&missense_variant 0.83 pyrazinamide Uncertain significance
rpsA 1833604 c.63C>T synonymous_variant 0.86 pyrazinamide
rpsA 1833610 c.69C>A synonymous_variant 0.86 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.91 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.92 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.88 pyrazinamide
rpsA 1833718 c.177C>T synonymous_variant 0.83 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.82 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.81 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.79 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.8 pyrazinamide
rpsA 1833754 c.213G>A synonymous_variant 0.77 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.84 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.9 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.9 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.87 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.81 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.8 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.79 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834024 c.483G>A synonymous_variant 0.8 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.78 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.75 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 0.73 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.75 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 0.58 pyrazinamide
rpsA 1834148 c.607C>T synonymous_variant 0.62 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834154 c.613_615delAACinsCA frameshift_variant&missense_variant 0.56 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.64 pyrazinamide
rpsA 1834174 c.633C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.73 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.76 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.88 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.88 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 0.89 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.76 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 0.76 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.85 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.88 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 0.85 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834615 c.1074C>T synonymous_variant 0.77 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.79 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.46 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 0.78 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.75 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.69 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 0.64 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.64 linezolid
tsnR 1853408 c.-198C>T upstream_gene_variant 0.65 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.62 linezolid
tsnR 1853426 c.-180G>A upstream_gene_variant 0.53 linezolid
tsnR 1853429 c.-177G>T upstream_gene_variant 0.53 linezolid
tsnR 1854004 c.399T>G synonymous_variant 0.46 linezolid
tsnR 1854013 c.408G>C synonymous_variant 0.4 linezolid
tsnR 1854022 c.417C>T synonymous_variant 0.35 linezolid
tsnR 1854028 c.423G>A synonymous_variant 0.38 linezolid
tsnR 1854030 p.Arg142His missense_variant 0.4 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917948 c.9A>G synonymous_variant 0.47 capreomycin
tlyA 1917965 p.Ala9Val missense_variant 0.75 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.79 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.8 capreomycin
tlyA 1917987 c.48G>C synonymous_variant 0.79 capreomycin
tlyA 1917996 c.57A>C synonymous_variant 0.75 capreomycin
tlyA 1918002 p.Gln21His missense_variant 0.7 capreomycin
tlyA 1918008 c.69C>T synonymous_variant 0.71 capreomycin
tlyA 1918014 c.75G>A synonymous_variant 0.68 capreomycin
tlyA 1918022 p.Gly28Glu missense_variant 0.68 capreomycin
tlyA 1918047 c.108G>C synonymous_variant 0.66 capreomycin
tlyA 1918055 p.Ala39Val missense_variant 0.56 capreomycin
bacA 2062995 c.1734C>G synonymous_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062998 c.1731T>C synonymous_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063001 c.1728A>G synonymous_variant 0.47 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063013 c.1716C>A synonymous_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063016 c.1713G>C synonymous_variant 0.57 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063019 c.1710G>A synonymous_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063043 c.1686T>C synonymous_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063046 c.1683T>C synonymous_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063055 c.1674T>C synonymous_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063058 c.1671A>G synonymous_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063067 c.1662T>C synonymous_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063076 c.1653C>G synonymous_variant 0.62 streptomycin Not assoc w R - Interim
kanamycin
capreomycin
amikacin
bacA 2063205 c.1524T>G synonymous_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063211 c.1518G>T synonymous_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063214 c.1515G>C synonymous_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063238 c.1491G>C synonymous_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063253 c.1476G>A synonymous_variant 0.72 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
bacA 2063259 p.Glu490Asp missense_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063262 c.1467C>T synonymous_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063266 p.Gly488Asp missense_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063271 c.1458G>T synonymous_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063275 p.His485Arg missense_variant 0.72 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin
bacA 2063280 c.1449C>A synonymous_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063289 c.1440A>C synonymous_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063295 c.1434C>G synonymous_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063301 c.1428G>A synonymous_variant 0.67 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
bacA 2063307 c.1422G>C synonymous_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063484 c.1245C>T synonymous_variant 0.48 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063490 c.1239C>G synonymous_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063496 c.1233C>T synonymous_variant 0.58 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063499 c.1230A>G synonymous_variant 0.57 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063514 c.1215C>T synonymous_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063520 c.1209G>C synonymous_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063523 c.1204_1206delCATinsTC frameshift_variant&missense_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063529 c.1200A>G synonymous_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063538 c.1191A>G synonymous_variant 0.63 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063541 c.1188A>G synonymous_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063550 c.1179C>G synonymous_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063553 c.1176G>C synonymous_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063556 c.1173T>C synonymous_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063643 c.1086C>T synonymous_variant 0.47 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063646 c.1083G>A synonymous_variant 0.47 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063658 c.1071A>G synonymous_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063667 c.1062G>A synonymous_variant 0.64 streptomycin
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
bacA 2063676 c.1053C>G synonymous_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063697 c.1032A>G synonymous_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063703 c.1026C>T synonymous_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063715 c.1014T>C synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063724 c.1005T>C synonymous_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063730 c.999A>T synonymous_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063742 c.987G>C synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063751 c.978C>A synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063754 c.975T>C synonymous_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063760 c.969T>C synonymous_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063868 c.861T>G synonymous_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063892 c.837T>C synonymous_variant 0.62 streptomycin Not assoc w R - Interim
kanamycin
capreomycin
amikacin
bacA 2063895 c.834C>A synonymous_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063901 c.828C>T synonymous_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063916 c.813C>A synonymous_variant 0.48 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064063 c.666C>T synonymous_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064069 c.660G>A synonymous_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064096 p.Ala211Gly missense_variant 0.47 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064099 c.630G>C synonymous_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064155 p.Val192Ile missense_variant 0.37 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
bacA 2064165 c.564T>C synonymous_variant 0.48 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064192 c.537A>G synonymous_variant 0.55 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064207 c.522C>T synonymous_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064210 c.519A>G synonymous_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064219 c.510C>G synonymous_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064222 c.507G>A synonymous_variant 0.83 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
bacA 2064240 c.487_489delCAAinsAG frameshift_variant&synonymous_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064243 c.486A>C synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064254 p.His159Asp missense_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064258 c.471A>G synonymous_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064264 c.465C>G synonymous_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064269 c.460A>C synonymous_variant 0.84 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064296 c.433T>C synonymous_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064297 c.432C>T synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064312 c.417C>G synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064319 p.Thr137Val missense_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064327 c.400_402delCTGinsAA frameshift_variant&missense_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064339 c.388_390delGTGinsAC frameshift_variant&missense_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064357 c.372G>A synonymous_variant 0.47 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.35 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.38 streptomycin
kanamycin
capreomycin
amikacin
bacA 2065002 c.-274C>G upstream_gene_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101726 c.1317A>C synonymous_variant 0.46 ethionamide
delamanid
isoniazid
ndh 2101732 c.1311T>C synonymous_variant 0.59 ethionamide
delamanid
isoniazid
ndh 2101744 p.Asp433Glu missense_variant 0.6 ethionamide
delamanid
isoniazid
ndh 2101765 c.1278C>G synonymous_variant 0.63 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>G synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.67 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>C synonymous_variant 0.6 ethionamide
delamanid
isoniazid
ndh 2101795 c.1248G>C synonymous_variant 0.64 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2101807 p.Thr412Ser missense_variant 0.58 ethionamide
delamanid
isoniazid
ndh 2101812 p.Ile411Val missense_variant 0.58 ethionamide
delamanid
isoniazid
ndh 2101888 c.1155T>G synonymous_variant 0.79 ethionamide
delamanid
isoniazid
ndh 2101891 c.1152C>G synonymous_variant 0.79 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101899 p.Ile382Val missense_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2101920 c.1123A>C synonymous_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 0.83 ethionamide
delamanid
isoniazid
ndh 2101936 c.1107G>C synonymous_variant 0.81 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>G synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>C synonymous_variant 0.78 ethionamide
delamanid
isoniazid
ndh 2101963 c.1080G>A synonymous_variant 0.76 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101971 p.Glu358Gln missense_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2101972 c.1069_1071delGCGinsAT frameshift_variant&missense_variant 0.65 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101980 p.Asn355Asp missense_variant 0.65 ethionamide
delamanid
isoniazid
ndh 2101984 c.1059C>G synonymous_variant 0.65 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 0.59 ethionamide
delamanid
isoniazid
ndh 2101999 c.1044G>A synonymous_variant 0.55 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102010 p.Ser345Gly missense_variant 0.48 ethionamide
delamanid
isoniazid
ndh 2102015 p.Val343Ala missense_variant 0.42 ethionamide
delamanid
isoniazid
ndh 2102247 p.Val266Ile missense_variant 0.69 ethionamide
delamanid
isoniazid
ndh 2102263 c.780G>A synonymous_variant 0.78 ethionamide
delamanid
isoniazid
ndh 2102287 c.756C>A synonymous_variant 0.79 ethionamide
delamanid
isoniazid
ndh 2102302 c.741G>C synonymous_variant 0.79 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 0.61 ethionamide
delamanid
isoniazid
ndh 2102332 c.709_711delCAGinsGA frameshift_variant&missense_variant 0.58 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102337 c.706T>C synonymous_variant 0.53 ethionamide Not assoc w R - Interim
delamanid
isoniazid
ndh 2102344 c.699T>C synonymous_variant 0.5 ethionamide
delamanid
isoniazid
ndh 2102350 c.693G>C synonymous_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2102626 c.417G>A synonymous_variant 0.43 ethionamide
delamanid
isoniazid
ndh 2102635 c.408C>G synonymous_variant 0.5 ethionamide
delamanid
isoniazid
ndh 2102638 c.405A>G synonymous_variant 0.53 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.71 ethionamide
delamanid
isoniazid
ndh 2102653 c.390T>C synonymous_variant 0.71 ethionamide
delamanid
isoniazid
ndh 2102668 c.375T>C synonymous_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>C synonymous_variant 0.65 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102677 c.366C>G synonymous_variant 0.65 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 0.65 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>G synonymous_variant 0.65 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 0.65 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>G synonymous_variant 0.68 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>C synonymous_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102908 c.135C>T synonymous_variant 0.92 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102911 c.132G>C synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102919 c.124C>T synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102932 c.111C>T synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102938 c.105G>T synonymous_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2102962 c.81A>C synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2102965 c.78G>C synonymous_variant 0.85 ethionamide
delamanid
isoniazid
ndh 2102974 c.69G>A synonymous_variant 0.79 ethionamide
delamanid
isoniazid
ndh 2102989 c.54G>C synonymous_variant 0.68 ethionamide
delamanid
isoniazid
ndh 2102992 c.51T>C synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2103008 p.Pro12Arg missense_variant 0.6 ethionamide
delamanid
isoniazid
ndh 2103012 p.Pro11Thr missense_variant 0.57 ethionamide
delamanid
isoniazid
katG 2155017 c.1095G>C synonymous_variant 0.57 isoniazid
katG 2155032 c.1080T>C synonymous_variant 0.56 isoniazid Not assoc w R - Interim
katG 2155047 c.1065C>T synonymous_variant 0.5 isoniazid
katG 2155054 p.Tyr353Phe missense_variant 0.5 isoniazid
katG 2155056 c.1056A>G synonymous_variant 0.5 isoniazid
katG 2155062 c.1050T>C synonymous_variant 0.5 isoniazid
katG 2155065 c.1047C>A synonymous_variant 0.5 isoniazid Not assoc w R - Interim
katG 2155068 c.1044T>C synonymous_variant 0.53 isoniazid
katG 2155071 c.1041T>A synonymous_variant 0.5 isoniazid
katG 2155080 c.1032G>C synonymous_variant 0.5 isoniazid
katG 2155581 c.531C>A synonymous_variant 0.41 isoniazid
katG 2155596 c.516G>C synonymous_variant 0.52 isoniazid
katG 2155600 p.Cys171Val missense_variant 0.5 isoniazid
katG 2155617 c.495T>C synonymous_variant 0.6 isoniazid Not assoc w R - Interim
katG 2155632 c.480A>C synonymous_variant 0.74 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.74 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.76 isoniazid Uncertain significance
katG 2155649 p.Tyr155His missense_variant 0.77 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.75 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.73 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.74 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.8 isoniazid
kasA 2517956 c.-159G>A upstream_gene_variant 0.73 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.67 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.65 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.62 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.61 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.58 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.58 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.6 isoniazid
kasA 2518046 c.-69C>G upstream_gene_variant 0.6 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.64 isoniazid
kasA 2518053 c.-62_-60delATTinsCC upstream_gene_variant 0.62 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 0.5 isoniazid
kasA 2518076 c.-39C>T upstream_gene_variant 0.48 isoniazid
kasA 2518187 p.Ile25Val missense_variant 0.56 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.68 isoniazid
kasA 2518252 c.138C>T synonymous_variant 0.7 isoniazid
kasA 2518279 c.165T>C synonymous_variant 0.71 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.72 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.67 isoniazid
kasA 2518300 c.186T>C synonymous_variant 0.67 isoniazid
kasA 2518312 c.198T>C synonymous_variant 0.63 isoniazid
kasA 2518318 c.204C>G synonymous_variant 0.66 isoniazid
kasA 2518323 p.Ser70Asn missense_variant 0.67 isoniazid
kasA 2518334 c.220_222delCGAinsAG frameshift_variant&synonymous_variant 0.69 isoniazid
kasA 2518339 c.225C>G synonymous_variant 0.67 isoniazid
kasA 2518348 c.234A>G synonymous_variant 0.69 isoniazid
kasA 2518360 c.246C>T synonymous_variant 0.64 isoniazid
kasA 2518374 p.Gly87Ala missense_variant 0.7 isoniazid
kasA 2518379 c.265T>C synonymous_variant 0.7 isoniazid
kasA 2518384 c.270G>C synonymous_variant 0.73 isoniazid
kasA 2518385 p.Gly91Ser missense_variant 0.73 isoniazid
kasA 2518393 p.Gln93His missense_variant 0.8 isoniazid
kasA 2518396 c.282A>C synonymous_variant 0.8 isoniazid
kasA 2518408 c.294C>G synonymous_variant 0.86 isoniazid
kasA 2518417 c.303G>C synonymous_variant 0.88 isoniazid
kasA 2518429 c.315A>G synonymous_variant 0.88 isoniazid
kasA 2518439 p.Ala109Thr missense_variant 0.86 isoniazid
kasA 2518444 c.330T>C synonymous_variant 0.86 isoniazid
kasA 2518447 c.333T>G synonymous_variant 0.86 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.7 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.7 isoniazid
kasA 2518468 c.354A>G synonymous_variant 0.68 isoniazid
kasA 2518471 c.357C>G synonymous_variant 0.68 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.73 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.76 isoniazid
kasA 2518492 c.378C>T synonymous_variant 0.72 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.62 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.62 isoniazid
kasA 2518513 c.399C>G synonymous_variant 0.64 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.63 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.69 isoniazid
kasA 2518537 c.423C>G synonymous_variant 0.68 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.79 isoniazid
kasA 2518567 c.453G>T synonymous_variant 0.79 isoniazid
kasA 2518573 c.459G>C synonymous_variant 0.74 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.74 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.78 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.76 isoniazid
kasA 2518618 c.504G>C synonymous_variant 0.78 isoniazid
kasA 2518633 c.519G>C synonymous_variant 0.78 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.77 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.75 isoniazid
kasA 2518648 c.534C>T synonymous_variant 0.76 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.8 isoniazid
kasA 2518681 c.567C>T synonymous_variant 0.8 isoniazid
kasA 2518684 c.570C>A synonymous_variant 0.81 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.81 isoniazid
kasA 2518714 c.600A>T synonymous_variant 0.81 isoniazid
kasA 2518735 c.621C>A synonymous_variant 0.82 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.83 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.86 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.85 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.8 isoniazid
kasA 2518789 c.675G>T synonymous_variant 0.8 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.81 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.82 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.82 isoniazid
kasA 2518822 c.708C>T synonymous_variant 0.81 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.82 isoniazid
kasA 2518855 c.741C>G synonymous_variant 0.82 isoniazid
kasA 2518856 p.Ile248Leu missense_variant 0.83 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.84 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.85 isoniazid
kasA 2518894 c.780G>A synonymous_variant 0.84 isoniazid
kasA 2518903 c.789C>T synonymous_variant 0.82 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.83 isoniazid
kasA 2518910 c.796C>T synonymous_variant 0.83 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.82 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.8 isoniazid
kasA 2518951 c.837G>A synonymous_variant 0.83 isoniazid
kasA 2518960 c.846C>G synonymous_variant 0.81 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.81 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.81 isoniazid
kasA 2518978 c.864T>C synonymous_variant 0.77 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.77 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.83 isoniazid
kasA 2518993 c.879C>G synonymous_variant 0.8 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 0.64 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 0.67 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 0.64 isoniazid
kasA 2519293 p.Asp393Glu missense_variant 0.55 isoniazid
kasA 2519295 p.Tyr394Phe missense_variant 0.55 isoniazid
kasA 2519302 c.1188C>T synonymous_variant 0.55 isoniazid
kasA 2519305 c.1191A>C synonymous_variant 0.55 isoniazid
kasA 2519306 p.Val398Ile missense_variant 0.55 isoniazid
ahpC 2726264 c.72C>G synonymous_variant 0.44 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 0.57 isoniazid
ahpC 2726304 p.Ile38Val missense_variant 0.57 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.57 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.61 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.59 isoniazid
ahpC 2726324 c.132A>G synonymous_variant 0.59 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 0.69 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.79 isoniazid
ahpC 2726354 c.162G>C synonymous_variant 0.77 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.76 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 0.8 isoniazid
ahpC 2726378 c.186T>G synonymous_variant 0.76 isoniazid
ahpC 2726393 c.201G>C synonymous_variant 0.78 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 0.75 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 0.78 isoniazid
ahpC 2726430 c.238_240delGCCinsAG frameshift_variant&missense_variant 0.67 isoniazid Uncertain significance
ahpC 2726441 c.249G>C synonymous_variant 0.5 isoniazid
folC 2746648 c.951G>C synonymous_variant 0.48 para-aminosalicylic_acid
folC 2746654 c.945C>G synonymous_variant 0.5 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.43 para-aminosalicylic_acid
folC 2746677 p.Ser308Ala missense_variant 0.43 para-aminosalicylic_acid
folC 2746678 c.921T>C synonymous_variant 0.43 para-aminosalicylic_acid
folC 2746681 c.918C>G synonymous_variant 0.41 para-aminosalicylic_acid
folC 2746684 c.915C>G synonymous_variant 0.41 para-aminosalicylic_acid
folC 2746687 c.910_912delCTCinsGG frameshift_variant&missense_variant 0.4 para-aminosalicylic_acid
folC 2746728 c.871T>C synonymous_variant 0.39 para-aminosalicylic_acid
folC 2747041 c.558G>C synonymous_variant 0.72 para-aminosalicylic_acid
folC 2747059 c.540T>A synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.73 para-aminosalicylic_acid
folC 2747071 c.528C>T synonymous_variant 0.74 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.72 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.72 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.68 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 0.68 para-aminosalicylic_acid
folC 2747221 c.378G>A synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747230 c.369C>G synonymous_variant 0.72 para-aminosalicylic_acid
folC 2747239 c.360T>C synonymous_variant 0.76 para-aminosalicylic_acid
folC 2747263 c.336C>A synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747278 c.321C>G synonymous_variant 0.81 para-aminosalicylic_acid
folC 2747288 p.Pro104Val missense_variant 0.87 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.73 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.57 para-aminosalicylic_acid
folC 2747398 c.201C>T synonymous_variant 0.6 para-aminosalicylic_acid
folC 2747404 c.195G>C synonymous_variant 0.7 para-aminosalicylic_acid
folC 2747414 p.Arg62Leu missense_variant 0.76 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747422 c.177G>A synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747425 c.174C>T synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747439 p.Met54Leu missense_variant 0.79 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747454 c.145C>A synonymous_variant 0.81 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 0.86 para-aminosalicylic_acid
folC 2747491 c.108A>G synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747497 c.102C>G synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747500 c.99A>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747503 c.96T>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747509 c.90T>C synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747520 c.79C>T synonymous_variant 0.69 para-aminosalicylic_acid
folC 2747521 c.78C>G synonymous_variant 0.67 para-aminosalicylic_acid
folC 2747524 c.75G>T synonymous_variant 0.67 para-aminosalicylic_acid
Rv2477c 2782441 c.1602G>A synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782459 c.1584C>T synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782462 c.1581C>G synonymous_variant 0.81 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782496 p.Asp516Ala missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782498 c.1545C>T synonymous_variant 0.85 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R
kanamycin Not assoc w R
rifampicin Not assoc w R
amikacin Not assoc w R
Rv2477c 2782504 c.1539G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>T synonymous_variant 0.68 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782570 c.1473C>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782576 c.1467C>T synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782587 p.Leu486Val missense_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782897 c.1146G>A synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782905 p.Val380Ile missense_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782918 c.1125C>T synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782928 p.Thr372Glu missense_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782930 c.1113G>A synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783122 c.921G>A synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783131 c.912C>T synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783143 c.900G>A synonymous_variant 0.66 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783188 c.855G>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783238 c.804_805insAC frameshift_variant 0.4 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783241 p.Glu268Lys missense_variant 0.4 ethambutol Uncertain significance
moxifloxacin
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783243 c.798_799delGA frameshift_variant 0.43 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783247 c.796T>C synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783248 c.795G>T synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783308 c.735G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>T synonymous_variant 0.76 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783356 c.687C>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783373 p.Glu224Gln missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783415 c.628C>T synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783416 c.627C>T synonymous_variant 0.68 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783419 c.624G>T synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 0.68 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783432 p.Ser204Ala missense_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>A synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783476 c.567C>T synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>T synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783515 c.528C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.62 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>A synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783587 c.456G>A synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783601 c.442C>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783602 c.441G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783632 c.411C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>A synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783644 p.Asp133Glu missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783658 c.385C>T synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783668 c.375G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.86 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783749 c.292_294delATCinsGA frameshift_variant&missense_variant 0.76 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783761 c.282G>A synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>T synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783842 c.201C>G synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783848 c.195C>T synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>T synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783866 c.177C>T synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783926 c.117C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783950 c.93C>T synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 c.87T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784016 c.27G>A synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784051 c.-9C>T upstream_gene_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784348 c.-306G>C upstream_gene_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784351 c.-309C>G upstream_gene_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784354 c.-312T>C upstream_gene_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784358 c.-316T>A upstream_gene_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784366 c.-324G>C upstream_gene_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784489 c.-447C>A upstream_gene_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784492 c.-450C>G upstream_gene_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784519 c.-477G>A upstream_gene_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784525 c.-483G>A upstream_gene_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784561 c.-519T>C upstream_gene_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859305 c.1114C>T synonymous_variant 0.48 clofazimine
bedaquiline
pepQ 2859318 c.1101A>G synonymous_variant 0.5 clofazimine
bedaquiline
pepQ 2859351 c.1068G>A synonymous_variant 0.42 clofazimine
bedaquiline
pepQ 2859431 c.988T>C synonymous_variant 0.76 clofazimine
bedaquiline
pepQ 2859438 c.981T>C synonymous_variant 0.77 clofazimine
bedaquiline
pepQ 2859468 c.951G>T synonymous_variant 0.87 clofazimine
bedaquiline
pepQ 2859489 p.Val310Ala missense_variant 0.89 clofazimine
bedaquiline
pepQ 2859510 c.909T>C synonymous_variant 0.84 clofazimine
bedaquiline
pepQ 2859528 c.891T>C synonymous_variant 0.75 clofazimine
bedaquiline
pepQ 2859540 c.879A>T synonymous_variant 0.69 clofazimine
bedaquiline
pepQ 2859546 c.873T>C synonymous_variant 0.65 clofazimine
bedaquiline
pepQ 2859555 p.Glu288Asp missense_variant 0.62 clofazimine
bedaquiline
pepQ 2859567 c.852C>G synonymous_variant 0.62 clofazimine
bedaquiline
pepQ 2859575 p.Ala282Thr missense_variant 0.55 clofazimine
bedaquiline
pepQ 2859581 c.838C>T synonymous_variant 0.5 clofazimine
bedaquiline
pepQ 2860259 c.160T>C synonymous_variant 0.69 clofazimine
bedaquiline
pepQ 2860263 c.156C>G synonymous_variant 0.69 clofazimine
bedaquiline
pepQ 2860266 p.Asp51Glu missense_variant 0.71 clofazimine
bedaquiline
pepQ 2860272 c.147G>A synonymous_variant 0.71 clofazimine
bedaquiline
pepQ 2860275 c.144T>C synonymous_variant 0.75 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2860293 c.126A>G synonymous_variant 0.75 clofazimine
bedaquiline
pepQ 2860314 c.105C>T synonymous_variant 0.61 clofazimine
bedaquiline
pepQ 2860317 c.102A>C synonymous_variant 0.61 clofazimine
bedaquiline
pepQ 2860329 c.90G>C synonymous_variant 0.57 clofazimine
bedaquiline
pepQ 2860332 c.87C>T synonymous_variant 0.55 clofazimine
bedaquiline
pepQ 2860345 p.Ser25Thr missense_variant 0.54 clofazimine
bedaquiline
pepQ 2860349 p.Ile24Val missense_variant 0.5 clofazimine
bedaquiline
pepQ 2860364 c.55T>C synonymous_variant 0.43 clofazimine
bedaquiline
pepQ 2860392 p.Lys9Asn missense_variant 0.52 clofazimine
bedaquiline
pepQ 2860397 p.Asp8His missense_variant 0.52 clofazimine
bedaquiline
pepQ 2860423 c.-5G>C upstream_gene_variant 0.67 clofazimine
bedaquiline
pepQ 2860447 c.-29A>G upstream_gene_variant 0.65 clofazimine
bedaquiline
pepQ 2860448 c.-30C>A upstream_gene_variant 0.65 clofazimine
bedaquiline
pepQ 2860475 c.-57C>T upstream_gene_variant 0.63 clofazimine
bedaquiline
pepQ 2860476 c.-58A>G upstream_gene_variant 0.63 clofazimine
bedaquiline
pepQ 2860480 c.-62G>A upstream_gene_variant 0.71 clofazimine
bedaquiline
pepQ 2860499 c.-81C>G upstream_gene_variant 0.53 clofazimine
bedaquiline
pepQ 2860503 c.-87_-85delGAGinsCC upstream_gene_variant 0.5 clofazimine
bedaquiline
Rv2681 2996200 c.-539G>C upstream_gene_variant 0.5 capreomycin
Rv2681 2996221 c.-518G>C upstream_gene_variant 0.53 capreomycin
Rv2681 2996227 c.-512A>G upstream_gene_variant 0.53 capreomycin
Rv2681 2996239 c.-500C>T upstream_gene_variant 0.53 capreomycin
Rv2681 2996248 c.-491A>T upstream_gene_variant 0.44 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 0.39 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 0.42 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>C upstream_gene_variant 0.47 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.55 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.48 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.45 capreomycin
Rv2681 2996539 c.-200T>C upstream_gene_variant 0.46 capreomycin
Rv2681 2996563 c.-176A>C upstream_gene_variant 0.48 capreomycin
Rv2681 2996575 c.-164C>T upstream_gene_variant 0.5 capreomycin
Rv2681 2996581 c.-158G>A upstream_gene_variant 0.5 capreomycin
Rv2681 2996593 c.-146T>C upstream_gene_variant 0.5 capreomycin
Rv2681 2996596 c.-143C>T upstream_gene_variant 0.48 capreomycin
Rv2681 2996602 c.-137G>C upstream_gene_variant 0.46 capreomycin
Rv2681 2996608 c.-131A>G upstream_gene_variant 0.48 capreomycin
Rv2681 2996668 c.-71C>T upstream_gene_variant 0.47 capreomycin
Rv2681 2996671 c.-68C>T upstream_gene_variant 0.5 capreomycin
Rv2681 2996674 c.-65G>C upstream_gene_variant 0.47 capreomycin
Rv2681 2996680 c.-59C>T upstream_gene_variant 0.5 capreomycin
Rv2681 2996683 c.-56G>C upstream_gene_variant 0.47 capreomycin
Rv2681 2996686 c.-53C>G upstream_gene_variant 0.44 capreomycin
Rv2681 2996692 c.-47G>A upstream_gene_variant 0.41 capreomycin
Rv2681 2996695 c.-44G>C upstream_gene_variant 0.41 capreomycin
Rv2680 2996708 p.Thr202Val missense_variant 0.44 capreomycin
Rv2680 2996717 p.Gly205Ser missense_variant 0.37 capreomycin
Rv2681 2996906 c.168A>G synonymous_variant 0.54 capreomycin
Rv2681 2996930 c.192C>T synonymous_variant 0.6 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 0.6 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 0.53 capreomycin
Rv2681 2996951 c.213C>T synonymous_variant 0.5 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 0.55 capreomycin
Rv2681 2996966 c.228G>T synonymous_variant 0.58 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 0.63 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 0.61 capreomycin
Rv2681 2996996 c.258C>T synonymous_variant 0.61 capreomycin
Rv2681 2997071 c.333C>T synonymous_variant 0.71 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 0.76 capreomycin
Rv2681 2997098 c.360C>G synonymous_variant 0.78 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 0.81 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 0.81 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 0.81 capreomycin Not assoc w R - Interim
Rv2681 2997126 c.388_390delCCAinsTG frameshift_variant&stop_gained 0.77 capreomycin Uncertain significance
Rv2681 2997134 c.396A>C synonymous_variant 0.76 capreomycin
Rv2681 2997149 c.411T>C synonymous_variant 0.77 capreomycin
Rv2681 2997155 c.417G>A synonymous_variant 0.78 capreomycin
Rv2681 2997176 c.438A>G synonymous_variant 0.74 capreomycin
Rv2681 2997183 c.445C>T synonymous_variant 0.73 capreomycin
Rv2681 2997189 p.Ala151Thr missense_variant 0.76 capreomycin
Rv2681 2997203 c.465G>A synonymous_variant 0.7 capreomycin
Rv2681 2997206 c.468A>G synonymous_variant 0.67 capreomycin
Rv2681 2997209 c.471T>G synonymous_variant 0.66 capreomycin Not assoc w R - Interim
Rv2681 2997212 c.474A>T synonymous_variant 0.68 capreomycin
Rv2681 2997218 c.480A>G synonymous_variant 0.7 capreomycin
Rv2681 2997219 c.481T>C synonymous_variant 0.7 capreomycin
Rv2681 2997222 p.Thr162Ala missense_variant 0.7 capreomycin
Rv2681 2997257 c.519C>T synonymous_variant 0.6 capreomycin
Rv2681 2997260 c.522G>A synonymous_variant 0.57 capreomycin
Rv2681 2997263 c.525A>G synonymous_variant 0.56 capreomycin
Rv2681 2997266 c.528C>A synonymous_variant 0.56 capreomycin
Rv2681 2997267 p.Ser177Pro missense_variant 0.56 capreomycin
Rv2752c 3064557 c.1635T>C synonymous_variant 0.68 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064566 c.1626G>C synonymous_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064590 c.1602C>T synonymous_variant 0.74 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064596 c.1596G>C synonymous_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064599 c.1593A>G synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064602 c.1590T>G synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064612 p.Ile527Thr missense_variant 0.72 ethambutol Uncertain significance
moxifloxacin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064614 c.1578G>C synonymous_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064635 c.1557G>C synonymous_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064640 c.1552T>C synonymous_variant 0.68 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064653 c.1539A>G synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064656 c.1536G>A synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064659 c.1533G>C synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065163 c.1029C>A synonymous_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.988_990delGCTinsTG frameshift_variant&missense_variant 0.78 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065210 c.982T>C synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065211 c.981G>T synonymous_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065217 c.975C>T synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065226 c.966G>A synonymous_variant 0.68 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065229 c.963G>C synonymous_variant 0.68 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.68 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 0.63 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065244 c.948G>T synonymous_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065262 c.930G>A synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065400 c.792A>G synonymous_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065406 c.786C>G synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065412 c.780G>A synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065430 c.762A>T synonymous_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065442 c.750T>C synonymous_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065451 c.741G>A synonymous_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>T synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065502 p.Asp230Glu missense_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 0.63 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065517 c.673_675delCTCinsTG frameshift_variant&synonymous_variant 0.76 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065532 c.660A>C synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065556 c.636G>A synonymous_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065583 c.609G>C synonymous_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065594 c.598C>T synonymous_variant 0.7 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065612 p.Thr194Ala missense_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065625 c.567G>C synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 0.68 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065652 c.540C>A synonymous_variant 0.66 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065658 p.Pro178Leu missense_variant 0.61 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.63 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065666 c.526T>C synonymous_variant 0.63 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065699 p.Ile165Val missense_variant 0.62 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065703 c.489A>C synonymous_variant 0.59 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065889 c.303G>C synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065892 c.300C>T synonymous_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>T synonymous_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065916 c.276T>C synonymous_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065919 c.273G>C synonymous_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065925 c.267G>C synonymous_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065947 p.Gly82Ala missense_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065952 c.240C>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065982 c.210G>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065993 p.Val67Ile missense_variant 0.5 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066498 c.-307C>G upstream_gene_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-311_-310delCGinsTC upstream_gene_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066513 c.-322C>A upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>T upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066552 c.-361C>T upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066592 c.-401A>C upstream_gene_variant 0.76 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066630 c.-439G>C upstream_gene_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066648 c.-457C>T upstream_gene_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.48 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066657 c.-466C>A upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066783 c.-592G>C upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066816 c.-625G>T upstream_gene_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-633_-631delGCTinsTC upstream_gene_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066855 c.-664T>C upstream_gene_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>G upstream_gene_variant 0.59 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>G upstream_gene_variant 0.63 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066945 c.-754C>G upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066957 c.-766C>T upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066972 c.-781C>T upstream_gene_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>C upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066984 c.-793C>T upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066990 c.-799G>A upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066996 c.-805T>C upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066999 c.-808C>G upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067006 c.-815A>G upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067008 c.-817C>T upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067011 c.-820C>G upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067017 c.-826G>T upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067028 c.-837A>G upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067044 c.-853C>G upstream_gene_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067051 c.-860G>C upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067055 c.-864A>G upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067056 c.-865T>C upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067059 c.-868G>A upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067083 c.-892C>A upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067086 c.-895A>G upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067089 c.-900_-898delCTAinsTG upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067100 c.-909G>C upstream_gene_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067247 c.699C>A synonymous_variant 0.63 para-aminosalicylic_acid
thyX 3067250 c.696G>C synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067277 c.669C>A synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067280 p.Val222Ser missense_variant 0.71 para-aminosalicylic_acid
thyX 3067284 p.Ala221Asp missense_variant 0.71 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067331 c.615C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067394 c.552G>T synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067430 c.516C>T synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067445 c.501C>A synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067742 c.204A>T synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.71 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067784 c.162C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 0.72 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067832 c.114C>T synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067847 c.97_99delCCCinsTG frameshift_variant&missense_variant 0.71 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.63 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067889 c.55_57delGCCinsAG frameshift_variant&missense_variant 0.65 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.61 para-aminosalicylic_acid
thyX 3067916 p.Gln10His missense_variant 0.55 para-aminosalicylic_acid
thyX 3067925 c.21G>A synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3073878 c.594G>A synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3073887 p.Ser195Asp missense_variant 0.5 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3073894 p.Gly193Asp missense_variant 0.5 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.53 para-aminosalicylic_acid
thyA 3073902 c.570C>A synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073932 c.540C>T synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3073947 c.525G>C synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.84 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 0.84 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.84 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.84 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.74 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.76 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 0.76 para-aminosalicylic_acid
thyA 3074091 c.381C>G synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3074123 p.Asp117Asn missense_variant 0.75 para-aminosalicylic_acid
thyA 3074127 c.345G>T synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3074133 c.339C>T synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3074151 c.321G>A synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074160 c.312A>T synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074163 c.309T>C synonymous_variant 0.78 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.78 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.65 para-aminosalicylic_acid
thyA 3074190 c.282C>T synonymous_variant 0.65 para-aminosalicylic_acid
thyA 3074196 c.276G>T synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3074199 c.273G>A synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.75 para-aminosalicylic_acid
thyA 3074208 c.264C>T synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3074214 p.Asp86Glu missense_variant 0.73 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3074247 c.225C>T synonymous_variant 0.76 para-aminosalicylic_acid
thyA 3074252 p.Glu74Gln missense_variant 0.74 para-aminosalicylic_acid
thyA 3074256 c.216G>A synonymous_variant 0.72 para-aminosalicylic_acid
thyA 3074262 c.210T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3074283 c.189G>A synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 0.75 para-aminosalicylic_acid
thyA 3074355 c.117G>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3074367 c.103_105delCGCinsAG frameshift_variant&missense_variant 0.71 para-aminosalicylic_acid
thyA 3074370 p.Met34Ile missense_variant 0.71 para-aminosalicylic_acid
thyA 3074391 c.81C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074397 c.75A>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3074409 c.63C>T synonymous_variant 0.6 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087699 p.Leu294Val missense_variant 0.39 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.43 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.43 cycloserine
ald 3087727 p.Ala303Gly missense_variant 0.45 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.45 cycloserine
ald 3087738 p.Lys307Arg missense_variant 0.42 cycloserine
ald 3087743 c.924G>A synonymous_variant 0.42 cycloserine
ald 3087746 c.927G>C synonymous_variant 0.42 cycloserine
ald 3087749 c.930C>G synonymous_variant 0.42 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 0.4 cycloserine
ald 3087771 p.Met318Leu missense_variant 0.43 cycloserine
ald 3087776 c.957G>C synonymous_variant 0.5 cycloserine
fbiD 3339171 c.54C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339177 c.60C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339180 c.63G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339186 c.69A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339190 c.73A>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339639 c.522C>T synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiD 3339642 c.525T>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiD 3339651 c.534G>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiD 3339654 c.537A>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiD 3339666 c.549G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiD 3339675 c.558C>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
Rv3236c 3612628 c.489G>C synonymous_variant 0.5 pyrazinamide
Rv3236c 3612667 c.450T>G synonymous_variant 0.72 pyrazinamide
Rv3236c 3612673 c.444G>C synonymous_variant 0.72 pyrazinamide
Rv3236c 3612679 c.438G>C synonymous_variant 0.72 pyrazinamide
Rv3236c 3612688 c.429C>G synonymous_variant 0.68 pyrazinamide
Rv3236c 3612691 c.426G>C synonymous_variant 0.68 pyrazinamide
Rv3236c 3612694 c.423T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
Rv3236c 3612706 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.62 pyrazinamide Uncertain significance
Rv3236c 3612712 c.405G>A synonymous_variant 0.62 pyrazinamide
Rv3236c 3612721 c.396G>C synonymous_variant 0.53 pyrazinamide
Rv3236c 3612805 c.312T>C synonymous_variant 0.59 pyrazinamide
Rv3236c 3612829 c.288T>C synonymous_variant 0.55 pyrazinamide
Rv3236c 3612835 c.282T>C synonymous_variant 0.55 pyrazinamide
Rv3236c 3612838 c.279G>C synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
Rv3236c 3612850 c.267C>T synonymous_variant 0.58 pyrazinamide
Rv3236c 3612853 c.264C>T synonymous_variant 0.61 pyrazinamide
Rv3236c 3612856 c.261C>T synonymous_variant 0.65 pyrazinamide
Rv3236c 3612862 c.255T>C synonymous_variant 0.65 pyrazinamide
lpqB 3623384 c.1527C>T synonymous_variant 0.47 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623388 p.Thr508Asn missense_variant 0.5 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 0.53 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 0.65 bedaquiline
rifampicin
lpqB 3623428 c.1483T>C synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3623443 p.Ser490Thr missense_variant 0.66 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 0.69 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623471 c.1440C>T synonymous_variant 0.78 bedaquiline
rifampicin
lpqB 3623489 c.1422C>T synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623492 c.1419T>C synonymous_variant 0.69 bedaquiline
rifampicin
lpqB 3623510 c.1401C>T synonymous_variant 0.64 bedaquiline
rifampicin
lpqB 3623531 p.Gly460Asp missense_variant 0.58 bedaquiline
rifampicin
lpqB 3623549 c.1362C>G synonymous_variant 0.45 bedaquiline
rifampicin
lpqB 3623561 c.1350T>C synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3623564 c.1347C>T synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 0.42 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3623576 c.1335T>C synonymous_variant 0.46 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 0.46 bedaquiline
rifampicin
lpqB 3623588 c.1323G>C synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3623684 c.1227T>C synonymous_variant 0.29 bedaquiline
rifampicin
lpqB 3623690 c.1221G>C synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3623699 c.1212C>G synonymous_variant 0.42 bedaquiline
rifampicin
lpqB 3623714 c.1197G>A synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3623732 c.1179G>T synonymous_variant 0.54 bedaquiline
rifampicin
lpqB 3623736 p.Ser392Asn missense_variant 0.54 bedaquiline
rifampicin
lpqB 3623738 c.1173C>T synonymous_variant 0.54 bedaquiline
rifampicin
lpqB 3623741 c.1170G>C synonymous_variant 0.52 bedaquiline
rifampicin
lpqB 3623750 c.1161C>G synonymous_variant 0.59 bedaquiline
rifampicin
lpqB 3623756 c.1155G>C synonymous_variant 0.56 bedaquiline
rifampicin
lpqB 3623782 p.Val377Ile missense_variant 0.65 bedaquiline
rifampicin
lpqB 3623789 c.1122T>C synonymous_variant 0.61 bedaquiline
rifampicin
lpqB 3623792 c.1119G>C synonymous_variant 0.59 bedaquiline
rifampicin
lpqB 3623799 p.Glu371Val missense_variant 0.5 bedaquiline
rifampicin
lpqB 3623987 c.924G>C synonymous_variant 0.45 bedaquiline
rifampicin
lpqB 3624002 c.909G>C synonymous_variant 0.52 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624008 c.903T>C synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624014 c.897T>C synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624017 p.Thr298Asn missense_variant 0.59 bedaquiline
rifampicin
lpqB 3624023 c.888G>A synonymous_variant 0.62 bedaquiline
rifampicin
lpqB 3624026 c.885G>A synonymous_variant 0.64 bedaquiline
rifampicin
lpqB 3624041 p.Glu290Asp missense_variant 0.68 bedaquiline
rifampicin
lpqB 3624071 c.840C>T synonymous_variant 0.81 bedaquiline
rifampicin
lpqB 3624080 c.831G>A synonymous_variant 0.86 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624094 c.817A>C synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3624098 c.813G>A synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624101 c.810C>A synonymous_variant 0.78 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>C synonymous_variant 0.7 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.65 bedaquiline
rifampicin
lpqB 3624152 c.759C>G synonymous_variant 0.66 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.5 bedaquiline
rifampicin
lpqB 3624290 c.621C>T synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624301 p.Ala204Ser missense_variant 0.72 bedaquiline
rifampicin
lpqB 3624302 c.609G>A synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624308 c.603A>G synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624314 c.597C>G synonymous_variant 0.7 bedaquiline
rifampicin
lpqB 3624317 c.594C>G synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 0.74 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 0.74 bedaquiline
rifampicin
lpqB 3624341 c.570C>T synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3624356 c.555C>T synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624368 c.543C>G synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 0.84 bedaquiline
rifampicin
lpqB 3624406 c.505C>T synonymous_variant 0.84 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 0.84 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 0.84 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3624467 c.444C>G synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3624482 c.429T>C synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624486 p.Asp142Gly missense_variant 0.76 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624490 p.Ser141Pro missense_variant 0.77 bedaquiline
rifampicin
lpqB 3624491 c.420G>C synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3624503 c.408G>A synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3624521 c.390G>C synonymous_variant 0.62 bedaquiline
rifampicin
lpqB 3624527 c.384A>G synonymous_variant 0.61 bedaquiline
rifampicin
lpqB 3624530 c.381T>C synonymous_variant 0.59 bedaquiline
rifampicin
lpqB 3624629 c.282G>T synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624635 c.276C>T synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624650 c.261G>C synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624671 c.240C>A synonymous_variant 0.58 bedaquiline
rifampicin
lpqB 3624680 c.231T>A synonymous_variant 0.58 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 0.64 bedaquiline
rifampicin Uncertain significance
lpqB 3624704 c.207G>A synonymous_variant 0.68 bedaquiline
rifampicin
lpqB 3624707 c.204G>A synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624713 c.198C>T synonymous_variant 0.74 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 0.56 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624749 c.162G>A synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624752 c.159C>G synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 0.5 bedaquiline
rifampicin Uncertain significance
lpqB 3624776 c.135T>C synonymous_variant 0.6 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 0.56 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 0.56 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624807 p.Val35Ala missense_variant 0.5 bedaquiline
rifampicin
lpqB 3624815 c.96A>G synonymous_variant 0.53 bedaquiline
rifampicin
mtrB 3625032 c.1582C>T synonymous_variant 0.62 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625045 c.-135C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3625089 p.Ala509Ser missense_variant 0.83 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Gln missense_variant 0.86 bedaquiline
rifampicin
lpqB 3625099 c.-189C>G upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625105 c.-195C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625111 c.-201G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625114 c.-204G>A upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.5 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.47 bedaquiline
rifampicin
lpqB 3625177 c.-267C>G upstream_gene_variant 0.48 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3625204 c.1408_1410delTCGinsGC frameshift_variant&missense_variant 0.56 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625216 c.-306G>A upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625231 c.-321G>A upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 0.71 bedaquiline
rifampicin
lpqB 3625273 c.-363C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625282 c.-372C>G upstream_gene_variant 0.77 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.8 bedaquiline
rifampicin
lpqB 3625309 c.-399C>T upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625327 c.-417A>G upstream_gene_variant 0.77 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
lpqB 3625366 c.-456C>A upstream_gene_variant 0.68 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
lpqB 3625384 c.-474G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
lpqB 3625387 c.-477T>C upstream_gene_variant 0.7 bedaquiline
rifampicin
lpqB 3625396 c.-486G>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3625405 c.1207_1209delCAGinsGA frameshift_variant&missense_variant 0.48 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625408 c.1204_1206delGAGinsCC frameshift_variant&missense_variant 0.48 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625414 c.-504C>G upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3625419 c.1195C>T synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625420 p.Asp398Glu missense_variant 0.52 bedaquiline
rifampicin
lpqB 3625426 c.-516G>C upstream_gene_variant 0.55 bedaquiline
rifampicin
lpqB 3625432 c.-522G>A upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625459 c.-549C>G upstream_gene_variant 0.74 bedaquiline
rifampicin
lpqB 3625465 c.-555T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
lpqB 3625471 c.-561C>G upstream_gene_variant 0.74 bedaquiline
rifampicin
lpqB 3625474 c.-564G>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3625480 p.Asn378Lys missense_variant 0.71 bedaquiline
rifampicin
lpqB 3625486 c.-576G>C upstream_gene_variant 0.74 bedaquiline
rifampicin
lpqB 3625489 c.-579A>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625497 c.1117T>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625510 c.-600T>G upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625518 c.-608T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
lpqB 3625522 c.-612C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.83 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.84 bedaquiline
rifampicin
lpqB 3625588 c.-678G>A upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625612 c.-702G>T upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625615 c.-705G>C upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625648 c.-738T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625663 c.-753G>C upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625684 c.-774G>A upstream_gene_variant 0.86 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625747 c.-837G>T upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3625750 c.864G>A synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.82 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.84 bedaquiline
rifampicin
lpqB 3625798 c.-888G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625803 c.-893C>T upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3625804 c.808_810delAGGinsCA frameshift_variant&missense_variant 0.83 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625819 c.795G>A synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625837 c.-927C>A upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625840 c.-930A>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3625945 c.669A>G synonymous_variant 0.56 bedaquiline
rifampicin
mtrB 3625951 c.663A>G synonymous_variant 0.62 bedaquiline
rifampicin
mtrB 3625959 p.Gly219Ser missense_variant 0.68 bedaquiline
rifampicin
mtrB 3625963 c.651C>G synonymous_variant 0.71 bedaquiline
rifampicin
mtrB 3625966 c.648C>A synonymous_variant 0.71 bedaquiline
rifampicin
mtrB 3625972 c.642G>C synonymous_variant 0.76 bedaquiline
rifampicin
mtrB 3625978 c.636T>C synonymous_variant 0.76 bedaquiline
rifampicin
mtrB 3625989 p.Thr209Ala missense_variant 0.7 bedaquiline
rifampicin
mtrB 3625993 c.621G>C synonymous_variant 0.7 bedaquiline
rifampicin
mtrB 3625999 c.615A>G synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626006 p.Ser203Asn missense_variant 0.63 bedaquiline
rifampicin
mtrB 3626008 c.606G>T synonymous_variant 0.63 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626029 c.585A>G synonymous_variant 0.61 bedaquiline
rifampicin
mtrB 3626043 p.Ala191Thr missense_variant 0.61 bedaquiline
rifampicin
mtrB 3626372 p.Ile81Thr missense_variant 0.5 bedaquiline
rifampicin
mtrB 3626383 c.231G>C synonymous_variant 0.5 bedaquiline
rifampicin
mtrB 3626386 c.228G>C synonymous_variant 0.5 bedaquiline
rifampicin
mtrB 3626390 p.Arg75Lys missense_variant 0.5 bedaquiline
rifampicin
mtrB 3626394 p.Val74Leu missense_variant 0.5 bedaquiline
rifampicin
mtrB 3626395 c.219G>A synonymous_variant 0.5 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 0.56 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 0.58 bedaquiline
rifampicin
mtrB 3626410 c.204T>G synonymous_variant 0.6 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626437 c.177T>C synonymous_variant 0.85 bedaquiline
rifampicin
mtrB 3626440 c.174C>G synonymous_variant 0.84 bedaquiline
rifampicin
mtrB 3626443 c.171T>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626455 c.159C>G synonymous_variant 0.95 bedaquiline
rifampicin
mtrB 3626458 c.156C>A synonymous_variant 0.9 bedaquiline
rifampicin
mtrB 3626461 c.153A>G synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626467 c.147G>T synonymous_variant 0.89 bedaquiline
rifampicin
mtrB 3626473 c.141T>G synonymous_variant 0.89 bedaquiline
rifampicin
mtrB 3626476 c.138C>G synonymous_variant 0.89 bedaquiline
rifampicin
mtrB 3626497 c.117G>A synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626502 c.112C>T synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626711 c.-98T>A upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626776 c.-163A>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626849 c.-236C>T upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3626852 c.-239G>A upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>C upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626936 c.-323C>A upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 0.72 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3626963 c.387G>A synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3626981 c.-368C>T upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626990 c.-377G>A upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3627002 c.-389G>A upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627056 c.294C>T synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3627140 c.-527G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3627155 c.-542C>T upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.9 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrA 3627227 c.123T>C synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627242 c.108C>T synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627266 c.-653A>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627296 c.-683T>A upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrA 3627311 c.39C>T synonymous_variant 0.68 bedaquiline Not assoc w R - Interim
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrA 3627323 c.25_27delTTGinsCC frameshift_variant&missense_variant 0.68 bedaquiline
rifampicin
mtrB 3627354 c.-741A>C upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrA 3627358 c.-9G>A upstream_gene_variant 0.56 bedaquiline
rifampicin Uncertain significance
mtrB 3627360 c.-747G>C upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3627362 c.-749A>T upstream_gene_variant 0.5 bedaquiline
rifampicin
fbiA 3640232 c.-311T>C upstream_gene_variant 0.5 clofazimine
pretomanid
delamanid
fbiA 3640247 c.-296T>G upstream_gene_variant 0.64 clofazimine
pretomanid
delamanid
fbiA 3640260 c.-283T>C upstream_gene_variant 0.63 clofazimine
pretomanid
delamanid
fbiA 3640261 c.-282C>T upstream_gene_variant 0.66 clofazimine
pretomanid
delamanid
fbiA 3640262 c.-281G>A upstream_gene_variant 0.68 clofazimine
pretomanid
delamanid
fbiA 3640269 c.-274A>C upstream_gene_variant 0.69 clofazimine
pretomanid
delamanid
fbiA 3640282 c.-261C>G upstream_gene_variant 0.74 clofazimine
pretomanid
delamanid
fbiA 3640298 c.-245A>G upstream_gene_variant 0.81 clofazimine
pretomanid
delamanid
fbiA 3640318 c.-225A>T upstream_gene_variant 0.83 clofazimine
pretomanid
delamanid
fbiA 3640365 c.-178C>G upstream_gene_variant 0.88 clofazimine
pretomanid
delamanid
fbiA 3640392 c.-151A>G upstream_gene_variant 0.62 clofazimine
pretomanid
delamanid
fbiA 3640393 c.-150A>C upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiA 3640394 c.-149G>A upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiA 3640400 c.-143G>C upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiA 3640402 c.-141C>G upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiA 3640403 c.-140G>C upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiA 3640413 c.-130T>C upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiA 3640414 c.-129G>A upstream_gene_variant 0.6 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiA 3640416 c.-127G>T upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiA 3640433 c.-110T>C upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiA 3640442 c.-101A>G upstream_gene_variant 0.58 clofazimine
pretomanid
delamanid
fbiA 3640445 c.-98A>C upstream_gene_variant 0.58 clofazimine
pretomanid
delamanid
fbiA 3641208 c.666C>T synonymous_variant 0.57 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiB 3641217 c.-318C>G upstream_gene_variant 0.62 clofazimine
pretomanid
delamanid
fbiB 3641226 c.-309G>C upstream_gene_variant 0.62 clofazimine
pretomanid
delamanid
fbiB 3641229 c.-306T>C upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiB 3641232 c.-303C>T upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiB 3641235 c.-300G>C upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiB 3641239 c.-296T>C upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiA 3641246 p.Glu235Ala missense_variant 0.53 clofazimine
pretomanid
delamanid
fbiA 3641251 p.Thr237Pro missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiB 3641256 c.-279A>G upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiA 3641286 c.744C>A synonymous_variant 0.54 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiA 3641288 p.Glu249Gly missense_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3641292 c.-243G>A upstream_gene_variant 0.52 clofazimine
pretomanid
delamanid
fbiA 3641314 p.Thr258Ala missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiB 3641319 c.-216C>T upstream_gene_variant 0.57 clofazimine
pretomanid
delamanid
fbiB 3641322 c.-213T>C upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3641328 c.-207T>A upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3641352 c.-183C>G upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3641355 c.-180T>G upstream_gene_variant 0.59 clofazimine
pretomanid
delamanid
fbiB 3641900 c.366G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiB 3641902 p.Val123Ala missense_variant 0.44 clofazimine
pretomanid
delamanid
fbiB 3641909 c.375T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiB 3641924 c.390A>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiB 3641925 p.Thr131Ala missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiB 3641928 c.394T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiB 3641948 c.414G>A synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiB 3641951 c.417G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiB 3641957 c.423C>T synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3641966 c.432C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiB 3641969 c.435C>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3641975 c.441C>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3641976 p.Ile148Val missense_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3641993 c.459A>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiB 3642665 c.1131C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiB 3642671 c.1137G>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiB 3642674 c.1140C>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiB 3642692 c.1158C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiB 3642695 c.1161G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3642707 c.1173C>T synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
alr 3840230 c.1191T>G synonymous_variant 0.67 cycloserine
alr 3840236 c.1185A>G synonymous_variant 0.7 cycloserine
alr 3840242 c.1179C>T synonymous_variant 0.75 cycloserine
alr 3840248 c.1173C>A synonymous_variant 0.8 cycloserine
alr 3840272 c.1149C>G synonymous_variant 0.75 cycloserine
alr 3840275 c.1146T>G synonymous_variant 0.77 cycloserine
alr 3840293 c.1128T>G synonymous_variant 0.81 cycloserine
alr 3840296 c.1125G>C synonymous_variant 0.81 cycloserine
alr 3840305 c.1116T>C synonymous_variant 0.77 cycloserine
alr 3840312 p.Ile370Ala missense_variant 0.79 cycloserine
alr 3840317 c.1104G>C synonymous_variant 0.79 cycloserine
alr 3840328 c.1093T>C synonymous_variant 0.77 cycloserine
alr 3840332 c.1089G>C synonymous_variant 0.73 cycloserine
alr 3840341 c.1080C>T synonymous_variant 0.61 cycloserine
alr 3840362 c.1059G>C synonymous_variant 0.53 cycloserine
alr 3840371 c.1050G>C synonymous_variant 0.57 cycloserine
alr 3840380 c.1039_1041delATGinsGC frameshift_variant&missense_variant 0.53 cycloserine
alr 3840443 c.978G>C synonymous_variant 0.61 cycloserine
alr 3840446 c.975G>T synonymous_variant 0.62 cycloserine
alr 3840473 c.948C>T synonymous_variant 0.61 cycloserine
alr 3840476 c.945A>C synonymous_variant 0.62 cycloserine
alr 3840502 p.Leu307Val missense_variant 0.54 cycloserine
alr 3840503 p.Asn306Thr missense_variant 0.54 cycloserine
alr 3840513 p.Arg303His missense_variant 0.57 cycloserine
alr 3840515 c.906A>G synonymous_variant 0.57 cycloserine
alr 3840527 c.894A>C synonymous_variant 0.62 cycloserine
alr 3840536 c.885T>C synonymous_variant 0.56 cycloserine
rpoA 3877482 c.1026C>A synonymous_variant 0.47 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 0.55 rifampicin Uncertain significance
rpoA 3877503 c.1003_1005delGCGinsTC frameshift_variant&missense_variant 0.52 rifampicin
rpoA 3877506 c.1002C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoA 3877512 c.996C>G synonymous_variant 0.52 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.56 rifampicin
rpoA 3877533 c.975C>G synonymous_variant 0.66 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877567 p.Ser314Thr missense_variant 0.72 rifampicin
rpoA 3877569 c.939G>C synonymous_variant 0.74 rifampicin
rpoA 3877575 c.933C>T synonymous_variant 0.76 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877602 c.906C>T synonymous_variant 0.86 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.88 rifampicin
rpoA 3877620 c.888G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>A synonymous_variant 0.87 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877659 c.849G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.75 rifampicin
rpoA 3877674 c.834C>T synonymous_variant 0.71 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.69 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877685 c.823C>T synonymous_variant 0.69 rifampicin
rpoA 3877689 c.819C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.72 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.71 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.67 rifampicin
rpoA 3877737 c.771G>T synonymous_variant 0.68 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877746 c.762G>C synonymous_variant 0.7 rifampicin
rpoA 3877752 c.756C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3877755 c.753C>A synonymous_variant 0.73 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 0.82 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.85 rifampicin
rpoA 3877886 c.622C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 0.81 rifampicin
rpoA 3877899 p.Ser203Thr missense_variant 0.73 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.82 rifampicin
rpoA 3877926 c.582G>C synonymous_variant 0.83 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 0.84 rifampicin
rpoA 3877950 c.558C>T synonymous_variant 0.85 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.83 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.78 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.83 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.79 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.77 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.77 rifampicin
rpoA 3878043 c.465G>T synonymous_variant 0.79 rifampicin
rpoA 3878058 c.450G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878061 c.447G>C synonymous_variant 0.76 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.81 rifampicin
rpoA 3878085 c.423G>A synonymous_variant 0.87 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 0.87 rifampicin
rpoA 3878100 c.408C>G synonymous_variant 0.93 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.91 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.91 rifampicin
rpoA 3878126 c.382C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878127 c.381G>C synonymous_variant 0.94 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.93 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.92 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 0.85 rifampicin
rpoA 3878211 c.297G>A synonymous_variant 0.83 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.82 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.91 rifampicin
rpoA 3878262 c.246C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.9 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 0.87 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878364 c.144A>T synonymous_variant 0.85 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.85 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.85 rifampicin
rpoA 3878376 c.132G>A synonymous_variant 0.85 rifampicin
rpoA 3878381 c.127C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878391 c.117T>A synonymous_variant 0.88 rifampicin
rpoA 3878403 c.105C>T synonymous_variant 0.85 rifampicin
rpoA 3878406 c.102G>T synonymous_variant 0.84 rifampicin
rpoA 3878412 c.96C>T synonymous_variant 0.82 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.86 rifampicin
rpoA 3878442 p.Val22Thr missense_variant 0.75 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.79 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.78 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.78 rifampicin
rpoA 3878483 c.25C>T synonymous_variant 0.78 rifampicin
rpoA 3878490 c.18C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878496 c.12A>T synonymous_variant 0.75 rifampicin
rpoA 3878512 c.-6_-5insGAA upstream_gene_variant 0.76 rifampicin Uncertain significance
rpoA 3878672 c.-165A>T upstream_gene_variant 0.45 rifampicin
rpoA 3878680 c.-173C>T upstream_gene_variant 0.56 rifampicin Uncertain significance
rpoA 3878698 c.-191A>C upstream_gene_variant 0.69 rifampicin
rpoA 3878713 c.-206G>C upstream_gene_variant 0.77 rifampicin
rpoA 3878719 c.-212G>A upstream_gene_variant 0.78 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.81 rifampicin
rpoA 3878728 c.-221G>A upstream_gene_variant 0.81 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.83 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.84 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.81 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoA 3878791 c.-284C>T upstream_gene_variant 0.81 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.84 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.81 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.77 rifampicin
rpoA 3878833 c.-326C>T upstream_gene_variant 0.77 rifampicin
rpoA 3878836 c.-330_-329delAGinsCC upstream_gene_variant 0.77 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.79 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.79 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.78 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.79 rifampicin Uncertain significance
rpoA 3878920 c.-413C>T upstream_gene_variant 0.78 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.7 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.73 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 0.72 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.71 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878977 c.-470C>G upstream_gene_variant 0.7 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.77 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.75 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGA upstream_gene_variant 0.77 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.82 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.86 rifampicin
rpoA 3879043 c.-536C>G upstream_gene_variant 0.86 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.81 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.83 rifampicin
rpoA 3879100 c.-593G>A upstream_gene_variant 0.8 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.71 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 0.68 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.65 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.66 rifampicin
rpoA 3879172 c.-665C>T upstream_gene_variant 0.68 rifampicin
rpoA 3879184 c.-677G>A upstream_gene_variant 0.65 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.65 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.54 rifampicin
ddn 3986636 c.-208C>A upstream_gene_variant 0.86 delamanid
pretomanid
ddn 3986637 c.-207C>T upstream_gene_variant 0.86 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.84 delamanid
pretomanid
ddn 3986657 c.-187C>G upstream_gene_variant 0.84 delamanid
pretomanid
ddn 3986663 c.-181G>A upstream_gene_variant 0.8 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.76 delamanid
pretomanid
ddn 3986696 c.-148G>T upstream_gene_variant 0.62 delamanid
pretomanid
ddn 3986930 c.87C>T synonymous_variant 0.53 delamanid
pretomanid
ddn 3986933 c.90C>A synonymous_variant 0.65 delamanid
pretomanid
ddn 3986941 p.Asp33Gly missense_variant 0.74 delamanid
pretomanid
ddn 3986945 c.102G>C synonymous_variant 0.74 delamanid
pretomanid
ddn 3986951 c.108T>C synonymous_variant 0.75 delamanid
pretomanid
ddn 3986954 c.111G>C synonymous_variant 0.76 delamanid
pretomanid
ddn 3986957 c.114C>T synonymous_variant 0.79 delamanid
pretomanid
ddn 3986975 c.132T>C synonymous_variant 0.83 delamanid
pretomanid
ddn 3986984 c.141G>T synonymous_variant 0.83 delamanid
pretomanid
ddn 3987020 c.177G>A synonymous_variant 0.86 delamanid
pretomanid
ddn 3987028 p.Asn62Ser missense_variant 0.73 delamanid
pretomanid
ddn 3987035 c.192C>G synonymous_variant 0.74 delamanid
pretomanid
ddn 3987053 c.210T>C synonymous_variant 0.73 delamanid
pretomanid
ddn 3987055 p.Gly71Asp missense_variant 0.73 delamanid
pretomanid
ddn 3987062 c.219C>G synonymous_variant 0.74 delamanid
pretomanid
ddn 3987065 c.222T>C synonymous_variant 0.76 delamanid
pretomanid
ddn 3987071 c.228G>C synonymous_variant 0.77 delamanid
pretomanid
ddn 3987089 c.246G>C synonymous_variant 0.7 delamanid
pretomanid
ddn 3987092 p.Glu83Asp missense_variant 0.7 delamanid Uncertain significance
pretomanid
ddn 3987098 c.255C>T synonymous_variant 0.75 delamanid
pretomanid
ddn 3987138 p.Gln99Ser missense_variant 0.59 delamanid
pretomanid
ddn 3987143 c.300A>G synonymous_variant 0.57 delamanid Not assoc w R - Interim
pretomanid
ddn 3987164 c.321G>C synonymous_variant 0.43 delamanid
pretomanid
ddn 3987167 c.324C>T synonymous_variant 0.43 delamanid
pretomanid
ddn 3987170 c.327T>C synonymous_variant 0.43 delamanid
pretomanid
ddn 3987179 c.336G>C synonymous_variant 0.39 delamanid
pretomanid
ddn 3987185 c.342G>C synonymous_variant 0.41 delamanid
pretomanid
clpC1 4038200 c.2505T>C synonymous_variant 0.69 pyrazinamide
clpC1 4038238 p.Thr823Ala missense_variant 0.75 pyrazinamide
clpC1 4038239 c.2466T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.73 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.73 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 0.75 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.75 pyrazinamide
clpC1 4038335 c.2370C>T synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038344 c.2361G>A synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4038350 c.2355C>G synonymous_variant 0.81 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.76 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038383 c.2322G>A synonymous_variant 0.79 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.77 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.8 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.78 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 0.83 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.83 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.84 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 0.85 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.86 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.83 pyrazinamide
clpC1 4038533 c.2172C>T synonymous_variant 0.83 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4038587 c.2118C>T synonymous_variant 0.81 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.84 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.77 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.77 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.63 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.6 pyrazinamide
clpC1 4038665 c.2040C>G synonymous_variant 0.63 pyrazinamide
clpC1 4038668 c.2037G>C synonymous_variant 0.63 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.65 pyrazinamide
clpC1 4038677 c.2028G>A synonymous_variant 0.73 pyrazinamide
clpC1 4038686 c.2019C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038695 c.2010C>A synonymous_variant 0.68 pyrazinamide
clpC1 4038698 c.2007C>G synonymous_variant 0.68 pyrazinamide
clpC1 4038703 c.2002C>T synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 0.69 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.68 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.75 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4038800 c.1905C>T synonymous_variant 0.8 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 0.74 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 0.77 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 0.87 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.86 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.79 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.75 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 0.73 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038995 c.1710G>A synonymous_variant 0.73 pyrazinamide
clpC1 4039009 c.1696C>T synonymous_variant 0.77 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.87 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.87 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.91 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.81 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.81 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 0.84 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 0.82 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.84 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039442 c.1261_1263delCTAinsTG frameshift_variant&synonymous_variant 0.86 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039484 c.1221T>G synonymous_variant 0.82 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4039514 c.1191C>T synonymous_variant 0.8 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039541 c.1164C>A synonymous_variant 0.81 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 0.77 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.77 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 0.72 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.8 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039693 c.1012C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.86 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039754 c.951G>T synonymous_variant 0.7 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>G synonymous_variant 0.68 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.6 pyrazinamide
clpC1 4039784 c.921C>T synonymous_variant 0.58 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4039904 c.801A>G synonymous_variant 0.8 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.74 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039942 c.763C>T synonymous_variant 0.8 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.81 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 0.75 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.65 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.64 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040033 c.672G>C synonymous_variant 0.66 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.63 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040091 c.613_614delTCinsAG synonymous_variant 0.76 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.86 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.76 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.72 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040171 c.534C>G synonymous_variant 0.62 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.58 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>G synonymous_variant 0.58 pyrazinamide
clpC1 4040531 c.174T>G synonymous_variant 0.59 pyrazinamide
clpC1 4040546 c.159G>T synonymous_variant 0.78 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.79 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.81 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.81 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040594 c.111G>T synonymous_variant 0.9 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.9 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.9 pyrazinamide
clpC1 4040636 c.69C>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040644 c.61A>C synonymous_variant 0.81 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.76 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4040662 c.43C>T synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4040674 c.31A>C synonymous_variant 0.67 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.67 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.69 pyrazinamide
panD 4044210 c.72C>G synonymous_variant 0.76 pyrazinamide
panD 4044219 c.63C>T synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
panD 4044224 c.58C>T synonymous_variant 0.71 pyrazinamide
panD 4044228 c.54C>G synonymous_variant 0.71 pyrazinamide
panD 4044243 c.39C>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
panD 4044246 c.36C>T synonymous_variant 0.75 pyrazinamide
panD 4044270 c.12G>A synonymous_variant 0.69 pyrazinamide
panD 4044644 c.-363A>G upstream_gene_variant 0.9 pyrazinamide
panD 4044647 c.-366C>T upstream_gene_variant 0.91 pyrazinamide
panD 4044662 c.-381C>G upstream_gene_variant 0.8 pyrazinamide
panD 4044672 c.-392_-391delGCinsCA upstream_gene_variant 0.77 pyrazinamide
panD 4044674 c.-393C>G upstream_gene_variant 0.77 pyrazinamide
panD 4044677 c.-396T>C upstream_gene_variant 0.77 pyrazinamide
panD 4044682 c.-401C>G upstream_gene_variant 0.77 pyrazinamide
panD 4044686 c.-407_-405delTTCinsCG upstream_gene_variant 0.8 pyrazinamide
panD 4044710 c.-429G>C upstream_gene_variant 0.81 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.75 pyrazinamide
panD 4044920 c.-639C>G upstream_gene_variant 0.58 pyrazinamide
panD 4044929 c.-648G>T upstream_gene_variant 0.69 pyrazinamide
panD 4044935 c.-654A>G upstream_gene_variant 0.65 pyrazinamide
panD 4044943 c.-662C>A upstream_gene_variant 0.61 pyrazinamide
panD 4044950 c.-669C>G upstream_gene_variant 0.5 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.47 pyrazinamide
panD 4044983 c.-702G>C upstream_gene_variant 0.47 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.47 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.53 pyrazinamide
panD 4045013 c.-732C>A upstream_gene_variant 0.5 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.47 pyrazinamide
panD 4045025 c.-744C>G upstream_gene_variant 0.47 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.5 pyrazinamide
panD 4045041 c.-761_-760delGTinsAC upstream_gene_variant 0.64 pyrazinamide
panD 4045045 c.-764C>A upstream_gene_variant 0.67 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.73 pyrazinamide
panD 4045063 c.-782T>C upstream_gene_variant 0.67 pyrazinamide
panD 4045067 c.-786C>T upstream_gene_variant 0.7 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.7 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.78 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.8 pyrazinamide
panD 4045094 c.-813T>G upstream_gene_variant 0.71 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.71 pyrazinamide
glpK 4138394 c.1362G>A synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138403 c.1353G>C synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138409 c.1347G>T synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138424 c.1332T>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138429 c.1327T>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138451 c.1305T>C synonymous_variant 0.62 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138456 c.1300C>T synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138459 p.Asp433Asn missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138465 p.Gly431Ser missense_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>A synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.622_624delCTAinsTG frameshift_variant&synonymous_variant 0.6 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139135 c.619_621delGATinsAC frameshift_variant&synonymous_variant 0.57 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139143 c.613T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139156 c.600C>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>G synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139189 c.567G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139540 p.Ile72Met missense_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139545 c.211T>C synonymous_variant 0.57 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139552 c.204G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139573 c.183C>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139579 c.177C>T synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139588 c.168G>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139594 c.162C>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139600 c.156G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139633 c.123C>T synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139651 p.His35Arg missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139693 c.63C>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139707 p.Ile17Val missense_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4238882 c.-981C>G upstream_gene_variant 0.56 ethambutol
embC 4238890 c.-973G>C upstream_gene_variant 0.53 ethambutol
embC 4238896 c.-967C>G upstream_gene_variant 0.53 ethambutol
embC 4238909 c.-954C>G upstream_gene_variant 0.61 ethambutol
embC 4238912 c.-951C>T upstream_gene_variant 0.61 ethambutol
embC 4238943 c.-920G>A upstream_gene_variant 0.68 ethambutol Uncertain significance
embC 4238954 c.-909C>T upstream_gene_variant 0.71 ethambutol
embC 4238963 c.-900C>T upstream_gene_variant 0.74 ethambutol Not assoc w R
embC 4238969 c.-894A>G upstream_gene_variant 0.7 ethambutol
embC 4238972 c.-891C>G upstream_gene_variant 0.65 ethambutol Uncertain significance
embC 4238975 c.-888A>C upstream_gene_variant 0.62 ethambutol
embC 4238986 c.-877C>A upstream_gene_variant 0.62 ethambutol
embC 4238999 c.-864C>G upstream_gene_variant 0.59 ethambutol Uncertain significance
embC 4239014 c.-849C>G upstream_gene_variant 0.62 ethambutol
embC 4239027 c.-836_-834delATCinsCG upstream_gene_variant 0.65 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 0.67 ethambutol Uncertain significance
embC 4239044 c.-819G>C upstream_gene_variant 0.74 ethambutol
embC 4239059 c.-804G>C upstream_gene_variant 0.72 ethambutol
embC 4239068 c.-795A>G upstream_gene_variant 0.72 ethambutol
embC 4239071 c.-792A>G upstream_gene_variant 0.78 ethambutol Uncertain significance
embC 4239075 c.-788_-786delGCGinsAC upstream_gene_variant 0.86 ethambutol
embC 4239079 c.-784_-783delCAinsGG upstream_gene_variant 0.86 ethambutol
embC 4239089 c.-774C>G upstream_gene_variant 0.82 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 0.81 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.7 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 0.65 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 0.62 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 0.59 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 0.55 ethambutol
embC 4239189 c.-674C>T upstream_gene_variant 0.44 ethambutol
embC 4239193 c.-670G>C upstream_gene_variant 0.4 ethambutol
embC 4239294 c.-569T>C upstream_gene_variant 0.8 ethambutol
embC 4239305 c.-558G>C upstream_gene_variant 0.8 ethambutol
embC 4239326 c.-537C>T upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4239336 c.-527T>C upstream_gene_variant 0.9 ethambutol
embC 4239344 c.-519G>C upstream_gene_variant 0.89 ethambutol
embC 4239354 c.-509A>G upstream_gene_variant 0.89 ethambutol Uncertain significance
embC 4239378 c.-485T>C upstream_gene_variant 0.85 ethambutol
embC 4239392 c.-471C>T upstream_gene_variant 0.74 ethambutol
embC 4239401 c.-462A>C upstream_gene_variant 0.73 ethambutol
embC 4240087 c.225T>C synonymous_variant 0.57 ethambutol
embC 4240093 c.231C>T synonymous_variant 0.63 ethambutol Not assoc w R - Interim
embC 4240105 p.Asp81Glu missense_variant 0.67 ethambutol
embC 4240106 c.244_246delTTGinsCC frameshift_variant&missense_variant 0.67 ethambutol
embC 4240123 c.261C>G synonymous_variant 0.73 ethambutol
embC 4240128 p.Gln89Arg missense_variant 0.73 ethambutol
embC 4240150 c.288A>G synonymous_variant 0.75 ethambutol
embC 4240151 p.Ser97Pro missense_variant 0.76 ethambutol
embC 4240171 c.309G>C synonymous_variant 0.78 ethambutol
embC 4240175 c.313T>C synonymous_variant 0.79 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.8 ethambutol
embC 4240201 c.339G>C synonymous_variant 0.71 ethambutol
embC 4240204 c.342T>C synonymous_variant 0.71 ethambutol Not assoc w R - Interim
embC 4240207 p.Lys115Asn missense_variant 0.71 ethambutol
embC 4240216 c.354T>C synonymous_variant 0.62 ethambutol
embC 4240228 c.366G>C synonymous_variant 0.57 ethambutol
embC 4240229 c.367_369delCTGinsAC frameshift_variant&missense_variant 0.62 ethambutol
embC 4240234 c.372A>G synonymous_variant 0.62 ethambutol
embC 4240237 c.375G>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embC 4240420 c.558T>C synonymous_variant 0.69 ethambutol
embC 4240427 p.Ser189Gly missense_variant 0.8 ethambutol
embC 4240441 c.579C>T synonymous_variant 0.75 ethambutol
embC 4240444 c.582C>G synonymous_variant 0.78 ethambutol
embC 4240471 c.609C>T synonymous_variant 0.79 ethambutol
embC 4240475 p.Ala205Ser missense_variant 0.79 ethambutol Uncertain significance
embC 4240484 c.622_624delGCGinsAA frameshift_variant&missense_variant 0.81 ethambutol
embC 4240489 c.627A>G synonymous_variant 0.81 ethambutol
embC 4240495 c.633T>C synonymous_variant 0.78 ethambutol
embC 4240512 p.Ser217Thr missense_variant 0.69 ethambutol
embC 4240516 c.654G>C synonymous_variant 0.67 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.64 ethambutol
embC 4240543 c.681G>C synonymous_variant 0.5 ethambutol
embC 4240632 p.Met257Thr missense_variant 0.53 ethambutol
embC 4240636 c.774G>C synonymous_variant 0.57 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.57 ethambutol
embC 4240646 p.Phe262Ile missense_variant 0.53 ethambutol
embC 4240654 c.792C>G synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embC 4240655 p.Ala265Gln missense_variant 0.57 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.75 ethambutol Not assoc w R
embC 4240678 c.816T>G synonymous_variant 0.78 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.75 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.77 ethambutol
embC 4240699 c.837C>A synonymous_variant 0.78 ethambutol
embC 4240717 c.855T>C synonymous_variant 0.8 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embC 4240741 c.879C>T synonymous_variant 0.83 ethambutol
embC 4240777 c.915G>A synonymous_variant 0.87 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.85 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.85 ethambutol
embC 4240795 c.933C>G synonymous_variant 0.85 ethambutol
embC 4240801 c.939C>T synonymous_variant 0.87 ethambutol
embC 4240831 c.969T>C synonymous_variant 0.88 ethambutol
embC 4240858 c.996G>A synonymous_variant 0.82 ethambutol
embC 4240859 p.Leu333Met missense_variant 0.82 ethambutol
embC 4240867 c.1005T>G synonymous_variant 0.82 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.81 ethambutol
embC 4240876 c.1014C>T synonymous_variant 0.81 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.83 ethambutol
embC 4240885 c.1023T>C synonymous_variant 0.82 ethambutol
embC 4240886 p.Ile342Val missense_variant 0.82 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.81 ethambutol Not assoc w R
embC 4240900 c.1038A>G synonymous_variant 0.81 ethambutol
embC 4240918 c.1056G>C synonymous_variant 0.76 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.74 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.74 ethambutol
embC 4240934 c.1072_1074delGTAinsTG frameshift_variant&stop_gained 0.65 ethambutol
embC 4240945 c.1083T>C synonymous_variant 0.7 ethambutol
embC 4240954 c.1092T>C synonymous_variant 0.74 ethambutol
embC 4240960 c.1098G>T synonymous_variant 0.74 ethambutol
embC 4240963 c.1101G>C synonymous_variant 0.74 ethambutol
embC 4240966 c.1104G>C synonymous_variant 0.74 ethambutol
embC 4240978 c.1116G>A synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embC 4240979 p.Thr373His missense_variant 0.68 ethambutol
embC 4240987 c.1125G>C synonymous_variant 0.76 ethambutol
embC 4240990 c.1128A>T synonymous_variant 0.8 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.84 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.83 ethambutol
embC 4241026 c.1164C>G synonymous_variant 0.88 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.94 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.95 ethambutol
embC 4241056 c.1194C>G synonymous_variant 0.98 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.93 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.91 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.84 ethambutol Not assoc w R - Interim
embC 4241153 p.Ile431Leu missense_variant 0.84 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.8 ethambutol
embC 4241167 c.1305C>G synonymous_variant 0.78 ethambutol
embC 4241185 c.1323G>C synonymous_variant 0.78 ethambutol
embC 4241197 c.1335G>C synonymous_variant 0.69 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.39 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.46 ethambutol
embC 4241383 c.1521G>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embC 4241386 c.1524C>G synonymous_variant 0.5 ethambutol
embC 4241392 c.1530G>C synonymous_variant 0.54 ethambutol
embC 4241401 c.1539C>T synonymous_variant 0.52 ethambutol
embC 4241416 c.1554C>A synonymous_variant 0.52 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.44 ethambutol
embC 4241728 c.1866C>T synonymous_variant 0.5 ethambutol
embC 4241741 p.Val627Ile missense_variant 0.58 ethambutol Uncertain significance
embC 4241750 p.Leu630Met missense_variant 0.64 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.68 ethambutol
embC 4241761 c.1899G>C synonymous_variant 0.75 ethambutol
embC 4241788 c.1926C>T synonymous_variant 0.74 ethambutol
embC 4241791 c.1929G>C synonymous_variant 0.77 ethambutol
embC 4241797 c.1935C>T synonymous_variant 0.71 ethambutol
embC 4241809 c.1947A>G synonymous_variant 0.71 ethambutol
embC 4241818 c.1956C>T synonymous_variant 0.62 ethambutol
embC 4241821 c.1959G>A synonymous_variant 0.61 ethambutol
embC 4241824 c.1962T>C synonymous_variant 0.58 ethambutol
embC 4241836 c.1974A>C synonymous_variant 0.56 ethambutol
embC 4241845 c.1983T>C synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embC 4241854 c.1992A>G synonymous_variant 0.3 ethambutol
embC 4242067 c.2205G>C synonymous_variant 0.68 ethambutol
embC 4242070 c.2208T>C synonymous_variant 0.7 ethambutol
embC 4242095 p.Ala745Thr missense_variant 0.67 ethambutol Uncertain significance
embC 4242106 c.2244C>G synonymous_variant 0.7 ethambutol
embC 4242127 c.2265G>A synonymous_variant 0.69 ethambutol
embC 4242128 c.2266C>T synonymous_variant 0.69 ethambutol
embC 4242139 c.2277G>C synonymous_variant 0.62 ethambutol
embC 4242146 c.2284_2286delAACinsGG frameshift_variant&missense_variant 0.5 ethambutol
embC 4242151 c.2289A>C synonymous_variant 0.5 ethambutol
embC 4242161 p.Ala767Pro missense_variant 0.44 ethambutol
embC 4242166 c.2304G>A synonymous_variant 0.44 ethambutol
embC 4242171 p.Thr770Ser missense_variant 0.44 ethambutol
embC 4242175 c.2313G>T synonymous_variant 0.44 ethambutol Not assoc w R - Interim
embC 4242179 c.2317_2319delTTGinsGT frameshift_variant&missense_variant 0.47 ethambutol
embC 4242190 c.2328C>T synonymous_variant 0.42 ethambutol Not assoc w R - Interim
embC 4242740 c.2878_2880delCTCinsTG frameshift_variant&missense_variant 0.74 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.79 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.81 ethambutol
embC 4242773 c.2911_2913delCTGinsTA frameshift_variant&stop_gained 0.76 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.78 ethambutol
embC 4242791 c.2929_2931delGCAinsTC frameshift_variant&missense_variant 0.77 ethambutol
embC 4242794 p.Ala978Lys missense_variant 0.8 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.84 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.79 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.77 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.76 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.64 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.63 ethambutol
embA 4242871 c.-362C>T upstream_gene_variant 0.63 ethambutol
embC 4242873 p.Asp1004Val missense_variant 0.65 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embC 4242885 p.Lys1008Thr missense_variant 0.65 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.67 ethambutol
embA 4242925 c.-308C>T upstream_gene_variant 0.52 ethambutol
embA 4243222 c.-11C>G upstream_gene_variant 0.58 ethambutol
embA 4243228 c.-5G>C upstream_gene_variant 0.62 ethambutol
embA 4243240 p.His3Leu missense_variant 0.84 ethambutol
embA 4243271 c.39A>C synonymous_variant 0.8 ethambutol
embA 4243279 p.Ala16Val missense_variant 0.79 ethambutol
embA 4243301 c.69G>C synonymous_variant 0.77 ethambutol
embA 4243304 c.72T>A synonymous_variant 0.73 ethambutol
embA 4243311 c.79C>T synonymous_variant 0.71 ethambutol
embA 4243318 p.Gly29Ala missense_variant 0.65 ethambutol
embA 4243320 c.88_90delATCinsCG frameshift_variant&missense_variant 0.65 ethambutol Uncertain significance
embA 4243334 c.102T>G synonymous_variant 0.6 ethambutol
embA 4243343 p.Asn37Lys missense_variant 0.39 ethambutol
embA 4243346 c.114A>G synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embA 4243349 c.117C>G synonymous_variant 0.38 ethambutol
embA 4243352 c.120C>G synonymous_variant 0.38 ethambutol
embA 4243460 c.228C>T synonymous_variant 0.8 ethambutol Not assoc w R
embA 4244099 c.867T>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embA 4244102 c.870A>C synonymous_variant 0.53 ethambutol
embA 4244117 c.885G>C synonymous_variant 0.63 ethambutol
embA 4244120 c.888T>C synonymous_variant 0.67 ethambutol
embA 4244132 c.900G>C synonymous_variant 0.7 ethambutol
embA 4244154 c.922_924delACAinsC frameshift_variant&missense_variant 0.69 ethambutol Uncertain significance
embA 4244165 c.933T>G synonymous_variant 0.67 ethambutol
embA 4244170 p.Gln313Arg missense_variant 0.63 ethambutol
embA 4244178 p.Ala316Ser missense_variant 0.65 ethambutol
embA 4244198 c.966C>A synonymous_variant 0.71 ethambutol
embA 4244207 c.975C>G synonymous_variant 0.72 ethambutol
embA 4244213 c.981C>G synonymous_variant 0.67 ethambutol
embA 4244283 p.Pro351Lys missense_variant 0.74 ethambutol
embA 4244291 c.1059G>C synonymous_variant 0.68 ethambutol
embA 4244306 c.1074G>C synonymous_variant 0.59 ethambutol
embA 4244308 p.Val359Ala missense_variant 0.59 ethambutol
embA 4244312 c.1080T>G synonymous_variant 0.62 ethambutol Not assoc w R - Interim
embA 4244316 c.1084_1086delTTCinsCG frameshift_variant&missense_variant 0.62 ethambutol Uncertain significance
embA 4244324 c.1092T>G synonymous_variant 0.67 ethambutol
embA 4244327 c.1095T>C synonymous_variant 0.63 ethambutol
embA 4244340 p.Ser370Ala missense_variant 0.73 ethambutol
embA 4244345 c.1113C>G synonymous_variant 0.72 ethambutol
embA 4244372 c.1140T>A synonymous_variant 0.74 ethambutol
embA 4244390 c.1158G>A synonymous_variant 0.64 ethambutol
embA 4244396 c.1164T>C synonymous_variant 0.64 ethambutol
embA 4244408 c.1176G>C synonymous_variant 0.6 ethambutol
embA 4244415 c.1183T>C synonymous_variant 0.55 ethambutol
embA 4244426 c.1194G>C synonymous_variant 0.53 ethambutol
embA 4244498 c.1266A>G synonymous_variant 0.73 ethambutol
embA 4244507 c.1275G>C synonymous_variant 0.73 ethambutol
embA 4244508 c.1276T>C synonymous_variant 0.8 ethambutol
embA 4244513 c.1281C>A synonymous_variant 0.8 ethambutol
embA 4244531 c.1299G>C synonymous_variant 0.83 ethambutol
embA 4244534 c.1302T>C synonymous_variant 0.83 ethambutol
embA 4244537 c.1305T>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embA 4244540 c.1308G>C synonymous_variant 0.86 ethambutol
embA 4244663 c.1431C>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embA 4244669 c.1437G>C synonymous_variant 0.67 ethambutol
embA 4244675 c.1443A>G synonymous_variant 0.67 ethambutol
embA 4244681 c.1449A>G synonymous_variant 0.71 ethambutol Not assoc w R - Interim
embA 4244684 c.1452C>G synonymous_variant 0.71 ethambutol
embA 4244702 c.1470C>G synonymous_variant 0.64 ethambutol
embA 4244705 c.1473G>C synonymous_variant 0.64 ethambutol
embA 4244708 c.1476C>G synonymous_variant 0.64 ethambutol
embA 4244714 c.1482C>G synonymous_variant 0.64 ethambutol
embA 4244792 c.1560G>C synonymous_variant 0.63 ethambutol
embA 4244802 p.Leu524Met missense_variant 0.54 ethambutol
embA 4244805 c.1573C>T synonymous_variant 0.54 ethambutol
embA 4244822 c.1590G>A synonymous_variant 0.74 ethambutol
embA 4244823 p.Val531Met missense_variant 0.71 ethambutol
embA 4244856 p.Ala542Pro missense_variant 0.86 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.85 ethambutol
embA 4244897 c.1665T>G synonymous_variant 0.82 ethambutol
embA 4244903 c.1671G>C synonymous_variant 0.76 ethambutol
embA 4244919 c.1687_1689delCTCinsTG frameshift_variant&missense_variant 0.73 ethambutol Uncertain significance
embA 4244930 c.1698G>C synonymous_variant 0.75 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.69 ethambutol
embA 4244939 c.1707G>A synonymous_variant 0.7 ethambutol
embA 4244946 c.1714_1716delGTGinsAC frameshift_variant&missense_variant 0.58 ethambutol Uncertain significance
embA 4245047 c.1815G>C synonymous_variant 0.52 ethambutol Not assoc w R - Interim
embA 4245051 c.1819_1821delGTGinsAC frameshift_variant&missense_variant 0.48 ethambutol Uncertain significance
embA 4245083 c.1851A>C synonymous_variant 0.68 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.71 ethambutol
embA 4245110 c.1878C>T synonymous_variant 0.76 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.67 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.73 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.64 ethambutol
embA 4245186 p.Thr652Ala missense_variant 0.62 ethambutol
embA 4245194 c.1962G>A synonymous_variant 0.56 ethambutol
embA 4245195 c.1963_1965delATCinsGG frameshift_variant&missense_variant 0.55 ethambutol Uncertain significance
embA 4245200 c.1968C>G synonymous_variant 0.55 ethambutol
embA 4245206 c.1974A>C synonymous_variant 0.57 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.57 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.62 ethambutol
embA 4245224 c.1992T>C synonymous_variant 0.69 ethambutol
embA 4245248 c.2016G>A synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embA 4245257 c.2025A>G synonymous_variant 0.64 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.68 ethambutol Not assoc w R - Interim
embA 4245281 c.2049C>G synonymous_variant 0.63 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.66 ethambutol
embA 4245293 c.2061T>A synonymous_variant 0.63 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.63 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.63 ethambutol
embA 4245300 c.2068C>T synonymous_variant 0.65 ethambutol
embA 4245311 c.2079C>T synonymous_variant 0.73 ethambutol
embA 4245326 c.2094C>G synonymous_variant 0.61 ethambutol
embA 4245327 p.Ala699Leu missense_variant 0.59 ethambutol
embA 4245345 p.Met705Leu missense_variant 0.62 ethambutol
embA 4245355 p.Ala708Gly missense_variant 0.55 ethambutol
embA 4245368 c.2136T>C synonymous_variant 0.52 ethambutol
embA 4245375 c.2143_2145delCTTinsAG frameshift_variant&missense_variant 0.6 ethambutol Uncertain significance
embA 4245402 c.2170_2172delACCinsGG frameshift_variant&missense_variant 0.45 ethambutol Uncertain significance
embA 4245409 c.2178_2179delCA frameshift_variant 0.47 ethambutol Uncertain significance
embA 4245413 p.Ser727Arg missense_variant 0.43 ethambutol
embA 4245414 c.2182_2183insAT frameshift_variant 0.45 ethambutol Uncertain significance
embA 4245424 c.2192_2193insGCCCAG disruptive_inframe_insertion 0.53 ethambutol
embA 4245431 c.2199T>C synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embA 4245434 c.2202G>C synonymous_variant 0.62 ethambutol
embA 4245458 c.2226G>A synonymous_variant 0.62 ethambutol
embA 4245464 c.2232C>T synonymous_variant 0.61 ethambutol
embA 4245473 c.2241C>T synonymous_variant 0.55 ethambutol
embA 4245488 c.2256G>C synonymous_variant 0.57 ethambutol
embA 4245497 c.2265C>T synonymous_variant 0.54 ethambutol
embA 4245501 c.2269_2271delGCGinsAC frameshift_variant&missense_variant 0.57 ethambutol Uncertain significance
embA 4245510 c.2278_2280delCCGinsTC frameshift_variant&missense_variant 0.48 ethambutol Uncertain significance
embA 4245524 c.2292G>C synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embB 4245551 c.-963A>G upstream_gene_variant 0.55 ethambutol
embA 4245566 c.2334C>T synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embB 4245575 c.-939C>G upstream_gene_variant 0.74 ethambutol
embB 4245594 c.-920_-919delTCinsAG upstream_gene_variant 0.78 ethambutol
embB 4245602 c.-912C>A upstream_gene_variant 0.76 ethambutol
embB 4245605 c.-909G>A upstream_gene_variant 0.78 ethambutol
embA 4245606 p.Leu792Val missense_variant 0.78 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 0.88 ethambutol
embB 4245623 c.-891G>A upstream_gene_variant 0.87 ethambutol
embB 4245662 c.-852G>C upstream_gene_variant 0.83 ethambutol
embA 4245674 c.2442A>T synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.82 ethambutol
embB 4245683 c.-831C>T upstream_gene_variant 0.81 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.83 ethambutol
embB 4245714 c.-800C>T upstream_gene_variant 0.82 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.8 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.8 ethambutol
embB 4245734 c.-780G>C upstream_gene_variant 0.78 ethambutol
embB 4245737 c.-777A>T upstream_gene_variant 0.78 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.7 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.68 ethambutol
embB 4245803 c.-711C>T upstream_gene_variant 0.64 ethambutol
embB 4245806 c.-708G>A upstream_gene_variant 0.62 ethambutol
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 0.62 ethambutol Uncertain significance
embB 4245812 c.-702G>T upstream_gene_variant 0.62 ethambutol
embA 4245813 p.Pro861Ala missense_variant 0.62 ethambutol
embA 4245822 p.Pro864Ala missense_variant 0.65 ethambutol
embB 4245839 c.-675G>C upstream_gene_variant 0.6 ethambutol
embA 4245843 c.2611_2613delGTTinsAC frameshift_variant&missense_variant 0.6 ethambutol Uncertain significance
embB 4245848 c.-666C>G upstream_gene_variant 0.6 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.64 ethambutol
embB 4245857 c.-657C>G upstream_gene_variant 0.69 ethambutol
embB 4245905 c.-609C>T upstream_gene_variant 0.86 ethambutol
embB 4245906 c.-608C>T upstream_gene_variant 0.86 ethambutol
embB 4245923 c.-591C>A upstream_gene_variant 0.87 ethambutol
embA 4245930 c.2698_2700delGGCinsCG frameshift_variant&missense_variant 0.91 ethambutol Uncertain significance
embA 4245935 c.2703G>C synonymous_variant 0.87 ethambutol Not assoc w R - Interim
embA 4245942 p.Arg904Gly missense_variant 0.88 ethambutol
embB 4245953 c.-561A>G upstream_gene_variant 0.83 ethambutol
embB 4245956 c.-558G>C upstream_gene_variant 0.8 ethambutol
embA 4245965 c.2733A>G synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4245968 c.-546T>C upstream_gene_variant 0.78 ethambutol
embA 4245978 p.Ile916Leu missense_variant 0.83 ethambutol
embB 4245983 c.-531A>G upstream_gene_variant 0.84 ethambutol
embB 4245992 c.-522C>G upstream_gene_variant 0.83 ethambutol
embB 4246004 c.-510T>C upstream_gene_variant 0.83 ethambutol
embB 4246005 c.-509C>T upstream_gene_variant 0.83 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 0.89 ethambutol
embA 4246020 p.Ala930Thr missense_variant 0.89 ethambutol
embA 4246028 c.2796G>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4246070 c.-444G>C upstream_gene_variant 0.92 ethambutol
embB 4246082 c.-432T>C upstream_gene_variant 0.89 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 0.83 ethambutol
embB 4246115 c.-399T>C upstream_gene_variant 0.84 ethambutol
embA 4246128 c.2896_2898delTCTinsAG frameshift_variant&synonymous_variant 0.8 ethambutol Uncertain significance
embA 4246138 p.Arg969Gln missense_variant 0.76 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 0.76 ethambutol
embB 4246148 c.-366G>C upstream_gene_variant 0.74 ethambutol
embB 4246151 c.-363A>C upstream_gene_variant 0.73 ethambutol
embA 4246152 p.Ala974Arg missense_variant 0.73 ethambutol
embB 4246172 c.-342C>T upstream_gene_variant 0.8 ethambutol
embB 4246184 c.-330A>C upstream_gene_variant 0.83 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.78 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.77 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.76 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.78 ethambutol
embA 4246227 c.2995_2997delATTinsGG frameshift_variant&missense_variant 0.76 ethambutol Uncertain significance
embA 4246235 c.3003G>A synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4246244 c.-270G>A upstream_gene_variant 0.78 ethambutol
embA 4246254 p.Leu1008Met missense_variant 0.79 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.77 ethambutol
embA 4246265 c.3033C>T synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embB 4246268 c.-246G>A upstream_gene_variant 0.74 ethambutol
embA 4246279 p.Ala1016Val missense_variant 0.71 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.7 ethambutol
embB 4246307 c.-207G>C upstream_gene_variant 0.76 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 0.78 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 0.78 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.77 ethambutol Uncertain significance
embB 4246373 c.-141T>C upstream_gene_variant 0.77 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.77 ethambutol
embA 4246398 p.Ser1056Thr missense_variant 0.78 ethambutol
embA 4246413 p.His1061Tyr missense_variant 0.75 ethambutol
embB 4246748 c.235_237delTTTinsCG frameshift_variant&missense_variant 0.58 ethambutol
embB 4246762 c.249G>T synonymous_variant 0.63 ethambutol
embB 4246768 c.255C>T synonymous_variant 0.6 ethambutol
embB 4246771 p.Asp86Glu missense_variant 0.63 ethambutol
embB 4246782 p.Ala90Gly missense_variant 0.71 ethambutol Uncertain significance
embB 4246784 p.Met91Leu missense_variant 0.71 ethambutol
embB 4246789 c.276A>G synonymous_variant 0.63 ethambutol
embB 4246792 c.279C>G synonymous_variant 0.63 ethambutol
embB 4246793 p.Ala94Gln missense_variant 0.63 ethambutol
embB 4246828 c.315A>G synonymous_variant 0.7 ethambutol
embB 4246843 c.330T>C synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embB 4246844 c.331T>C synonymous_variant 0.57 ethambutol
embB 4246853 p.Leu114Met missense_variant 0.55 ethambutol
embB 4246871 p.Ala120Ser missense_variant 0.61 ethambutol
embB 4246879 c.366C>G synonymous_variant 0.61 ethambutol
embB 4246882 c.369G>C synonymous_variant 0.61 ethambutol
embB 4246894 c.381C>T synonymous_variant 0.61 ethambutol
embB 4246910 c.397T>C synonymous_variant 0.5 ethambutol
embB 4247062 c.549G>C synonymous_variant 0.55 ethambutol
embB 4247089 c.576G>C synonymous_variant 0.79 ethambutol
embB 4247095 c.582G>A synonymous_variant 0.77 ethambutol
embB 4247104 c.591G>A synonymous_variant 0.77 ethambutol Not assoc w R - Interim
embB 4247113 c.600G>A synonymous_variant 0.73 ethambutol
embB 4247114 p.Ala201Lys missense_variant 0.73 ethambutol
embB 4247117 c.604_606delGTCinsCT frameshift_variant&missense_variant 0.73 ethambutol
embB 4247137 c.624C>G synonymous_variant 0.74 ethambutol
embB 4247140 c.627G>C synonymous_variant 0.74 ethambutol
embB 4247150 p.Arg213Thr missense_variant 0.77 ethambutol
embB 4247155 c.642G>A synonymous_variant 0.81 ethambutol
embB 4247179 p.Ile222Met missense_variant 0.67 ethambutol
embB 4247180 p.Ile223Val missense_variant 0.64 ethambutol
embB 4247185 c.672G>C synonymous_variant 0.62 ethambutol
embB 4247365 c.852A>C synonymous_variant 0.67 ethambutol
embB 4247370 p.Gly286Ala missense_variant 0.67 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.74 ethambutol
embB 4247398 c.885G>C synonymous_variant 0.79 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.79 ethambutol
embB 4247404 c.891G>C synonymous_variant 0.8 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.81 ethambutol
embB 4247440 c.927C>G synonymous_variant 0.84 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.82 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.85 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.88 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.85 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.76 ethambutol
embB 4247555 c.1042_1044delCTGinsAC frameshift_variant&missense_variant 0.76 ethambutol
embB 4247566 c.1053C>G synonymous_variant 0.76 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.68 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embB 4247608 c.1095G>C synonymous_variant 0.65 ethambutol
embB 4247611 c.1098G>C synonymous_variant 0.66 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.71 ethambutol
embB 4247645 p.Glu378Thr missense_variant 0.59 ethambutol
embB 4247648 p.Ala379Ser missense_variant 0.64 ethambutol
embB 4247657 p.Pro382Ala missense_variant 0.66 ethambutol
embB 4247671 c.1158G>A synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embB 4247679 p.Met389Thr missense_variant 0.66 ethambutol
embB 4247684 c.1171T>C synonymous_variant 0.68 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.77 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.75 ethambutol
embB 4247728 c.1215G>A synonymous_variant 0.74 ethambutol
embB 4247743 c.1230C>G synonymous_variant 0.73 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.7 ethambutol
embB 4247779 c.1266C>G synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 0.79 ethambutol
embB 4247800 c.1287A>C synonymous_variant 0.65 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.57 ethambutol
embB 4247816 p.Val435Ile missense_variant 0.57 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 0.57 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embB 4247858 c.1345C>T synonymous_variant 0.68 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.65 ethambutol
embB 4247911 p.Leu466Phe missense_variant 0.65 ethambutol
embB 4247915 p.Arg468Lys missense_variant 0.65 ethambutol
embB 4247920 c.1407T>C synonymous_variant 0.66 ethambutol
embB 4247923 c.1410T>C synonymous_variant 0.68 ethambutol
embB 4247932 c.1419C>G synonymous_variant 0.7 ethambutol
embB 4247948 p.Val479Leu missense_variant 0.75 ethambutol Uncertain significance
embB 4247975 p.Val488Ile missense_variant 0.68 ethambutol Uncertain significance
embB 4247989 c.1476G>C synonymous_variant 0.79 ethambutol
embB 4248001 c.1488C>T synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 0.82 ethambutol
embB 4248042 p.Ala510Gly missense_variant 0.78 ethambutol
embB 4248052 c.1539G>T synonymous_variant 0.79 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.79 ethambutol
embB 4248058 c.1545C>T synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embB 4248061 c.1548G>A synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embB 4248064 c.1551G>C synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.79 ethambutol
embB 4248094 c.1581C>T synonymous_variant 0.76 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.73 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.82 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.82 ethambutol
embB 4248154 c.1641G>T synonymous_variant 0.81 ethambutol
embB 4248157 c.1644A>T synonymous_variant 0.82 ethambutol
embB 4248163 c.1650G>A synonymous_variant 0.86 ethambutol
embB 4248169 c.1656C>T synonymous_variant 0.85 ethambutol Not assoc w R - Interim
embB 4248175 c.1662G>A synonymous_variant 0.87 ethambutol
embB 4248178 c.1665C>T synonymous_variant 0.88 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.87 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 0.86 ethambutol
embB 4248217 c.1704C>G synonymous_variant 0.87 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 0.85 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.84 ethambutol
embB 4248266 c.1753C>T synonymous_variant 0.81 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.81 ethambutol
embB 4248280 c.1767C>G synonymous_variant 0.81 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.84 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.84 ethambutol
embB 4248334 c.1821C>G synonymous_variant 0.84 ethambutol
embB 4248349 c.1836G>A synonymous_variant 0.85 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.83 ethambutol
embB 4248361 c.1848A>G synonymous_variant 0.85 ethambutol Not assoc w R - Interim
embB 4248379 c.1866G>A synonymous_variant 0.81 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 0.77 ethambutol
embB 4248412 p.Phe633Leu missense_variant 0.79 ethambutol
embB 4248416 p.Leu635Met missense_variant 0.79 ethambutol
embB 4248424 c.1911G>A synonymous_variant 0.79 ethambutol
embB 4248430 c.1917T>C synonymous_variant 0.79 ethambutol
embB 4248448 c.1935C>T synonymous_variant 0.81 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.78 ethambutol
embB 4248472 c.1959T>C synonymous_variant 0.78 ethambutol
embB 4248496 c.1983G>C synonymous_variant 0.79 ethambutol
embB 4248504 p.Asp664Ala missense_variant 0.76 ethambutol
embB 4248508 c.1995G>A synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4248514 c.2001A>G synonymous_variant 0.76 ethambutol
embB 4248535 c.2022C>G synonymous_variant 0.76 ethambutol
embB 4248541 c.2028T>C synonymous_variant 0.65 ethambutol
embB 4248544 c.2031G>C synonymous_variant 0.5 ethambutol
embB 4248547 c.2034C>T synonymous_variant 0.5 ethambutol
embB 4248553 c.2040C>G synonymous_variant 0.54 ethambutol
embB 4248555 p.Gly681Val missense_variant 0.54 ethambutol
embB 4248559 c.2046T>C synonymous_variant 0.5 ethambutol
embB 4248574 c.2061C>T synonymous_variant 0.46 ethambutol
embB 4248660 p.Ala716Val missense_variant 0.71 ethambutol Uncertain significance
embB 4248670 c.2157C>T synonymous_variant 0.76 ethambutol
embB 4248676 c.2163C>G synonymous_variant 0.76 ethambutol
embB 4248682 c.2169G>C synonymous_variant 0.77 ethambutol
embB 4248697 c.2184A>C synonymous_variant 0.86 ethambutol
embB 4248706 c.2193G>C synonymous_variant 0.84 ethambutol Not assoc w R - Interim
embB 4248731 p.Val740Leu missense_variant 0.83 ethambutol
embB 4248742 c.2229T>C synonymous_variant 0.8 ethambutol
embB 4248757 c.2244A>C synonymous_variant 0.75 ethambutol
embB 4249105 c.2592C>G synonymous_variant 0.3 ethambutol
embB 4249126 c.2613G>A synonymous_variant 0.4 ethambutol
embB 4249138 c.2625C>G synonymous_variant 0.48 ethambutol
embB 4249140 p.Val876Ala missense_variant 0.48 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.67 ethambutol
embB 4249348 c.2835G>C synonymous_variant 0.7 ethambutol
embB 4249360 c.2847G>C synonymous_variant 0.78 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.68 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.71 ethambutol
embB 4249381 c.2868A>C synonymous_variant 0.73 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.7 ethambutol
embB 4249429 c.2916C>G synonymous_variant 0.65 ethambutol
embB 4249459 c.2946G>A synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4249474 c.2961C>T synonymous_variant 0.67 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.67 ethambutol
embB 4249487 c.2974_2976delTTGinsCC frameshift_variant&missense_variant 0.65 ethambutol
embB 4249492 c.2979C>G synonymous_variant 0.68 ethambutol
embB 4249501 c.2988C>T synonymous_variant 0.67 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.62 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.61 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.62 ethambutol Uncertain significance
embB 4249540 c.3027C>T synonymous_variant 0.68 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.69 ethambutol
embB 4249568 p.Ser1019Asn missense_variant 0.72 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.69 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.74 ethambutol
embB 4249607 p.Thr1032Val missense_variant 0.73 ethambutol
embB 4249618 c.3105C>G synonymous_variant 0.82 ethambutol
embB 4249624 c.3111C>T synonymous_variant 0.78 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.74 ethambutol
embB 4249640 c.3127T>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embB 4249648 c.3135G>C synonymous_variant 0.78 ethambutol
embB 4249654 c.3141C>T synonymous_variant 0.71 ethambutol
embB 4249657 c.3144C>G synonymous_variant 0.67 ethambutol
embB 4249663 c.3150C>G synonymous_variant 0.67 ethambutol
embB 4249666 c.3153C>T synonymous_variant 0.67 ethambutol
embB 4249669 c.3156C>T synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4249675 c.3162C>G synonymous_variant 0.74 ethambutol
embB 4249693 c.3180T>C synonymous_variant 0.72 ethambutol
embB 4249699 c.3186T>A synonymous_variant 0.72 ethambutol
embB 4249702 c.3189C>A synonymous_variant 0.74 ethambutol
embB 4249703 c.3190C>T synonymous_variant 0.74 ethambutol
embB 4249711 c.3198G>A synonymous_variant 0.78 ethambutol
embB 4249735 c.3222T>G synonymous_variant 0.77 ethambutol
embB 4249741 c.3228C>A synonymous_variant 0.67 ethambutol
embB 4249744 c.3231G>A synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4249750 p.Glu1079Asp missense_variant 0.68 ethambutol
embB 4249751 c.3238T>C synonymous_variant 0.68 ethambutol
embB 4249774 c.3261C>A synonymous_variant 0.52 ethambutol
embB 4249775 c.3262C>T synonymous_variant 0.55 ethambutol
aftB 4267454 c.1383C>T synonymous_variant 0.68 ethambutol
aftB 4267483 c.1354T>C synonymous_variant 0.85 ethambutol
aftB 4267484 c.1353A>G synonymous_variant 0.85 ethambutol
aftB 4267489 c.1348T>C synonymous_variant 0.85 ethambutol
aftB 4267490 c.1347G>T synonymous_variant 0.85 ethambutol
aftB 4267493 c.1344G>C synonymous_variant 0.85 ethambutol
aftB 4267499 c.1338G>C synonymous_variant 0.9 ethambutol
aftB 4267510 p.Asn443Asp missense_variant 0.91 ethambutol
aftB 4267511 c.1326C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
aftB 4267517 c.1320A>C synonymous_variant 0.91 ethambutol
aftB 4267520 c.1317T>G synonymous_variant 0.91 ethambutol
aftB 4267529 c.1308T>C synonymous_variant 0.89 ethambutol
aftB 4267535 c.1302A>G synonymous_variant 0.9 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 0.8 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 0.81 ethambutol
aftB 4267580 c.1257G>A synonymous_variant 0.82 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 0.84 ethambutol Not assoc w R - Interim
aftB 4267622 c.1213_1215delTCGinsAC frameshift_variant&missense_variant 0.82 ethambutol Uncertain significance
aftB 4267634 p.Arg401His missense_variant 0.84 ethambutol
aftB 4267637 c.1200C>G synonymous_variant 0.84 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
aftB 4267667 c.1170A>G synonymous_variant 0.83 ethambutol
aftB 4267670 c.1167G>A synonymous_variant 0.82 ethambutol
aftB 4267685 c.1152T>C synonymous_variant 0.64 ethambutol
aftB 4267802 c.1035T>C synonymous_variant 0.53 ethambutol
aftB 4267805 c.1032T>C synonymous_variant 0.53 ethambutol
aftB 4267808 c.1029G>C synonymous_variant 0.56 ethambutol Not assoc w R - Interim
aftB 4267826 c.1011G>C synonymous_variant 0.73 ethambutol
aftB 4267838 c.999T>C synonymous_variant 0.8 ethambutol
aftB 4267841 c.996C>T synonymous_variant 0.83 ethambutol
aftB 4267856 c.981T>C synonymous_variant 0.82 ethambutol
aftB 4267879 p.Val320Leu missense_variant 0.71 ethambutol
aftB 4267891 p.Val316Ile missense_variant 0.7 ethambutol
aftB 4267892 p.Ile315Met missense_variant 0.7 ethambutol
aftB 4267898 c.939T>C synonymous_variant 0.74 ethambutol
aftB 4267907 c.930C>G synonymous_variant 0.71 ethambutol
aftB 4267912 p.Pro309Ala missense_variant 0.68 ethambutol
aftB 4267916 c.921T>C synonymous_variant 0.67 ethambutol
aftB 4267919 c.918A>G synonymous_variant 0.62 ethambutol
aftB 4267922 c.915G>A synonymous_variant 0.62 ethambutol
aftB 4267940 c.897T>G synonymous_variant 0.57 ethambutol
aftB 4267952 c.885A>G synonymous_variant 0.52 ethambutol
aftB 4267957 p.Leu294Val missense_variant 0.5 ethambutol
aftB 4267960 p.Val293Met missense_variant 0.44 ethambutol Uncertain significance
aftB 4267961 c.876C>G synonymous_variant 0.44 ethambutol
aftB 4268081 c.756A>G synonymous_variant 0.5 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.56 ethambutol
aftB 4268105 c.732T>C synonymous_variant 0.56 ethambutol
aftB 4268125 p.Ser238Gly missense_variant 0.57 ethambutol
aftB 4268126 c.711G>C synonymous_variant 0.57 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.57 ethambutol
aftB 4268134 c.703C>T synonymous_variant 0.57 ethambutol Not assoc w R - Interim
aftB 4268135 c.700_702delCTGinsTA frameshift_variant&synonymous_variant 0.59 ethambutol Uncertain significance
aftB 4268138 p.Gly233Ala missense_variant 0.62 ethambutol
aftB 4268144 c.693T>C synonymous_variant 0.65 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.64 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.48 ethambutol Not assoc w R - Interim
aftB 4268183 c.654A>C synonymous_variant 0.35 ethambutol
aftB 4268194 p.Leu215Val missense_variant 0.4 ethambutol
aftB 4268207 c.630C>G synonymous_variant 0.46 ethambutol
aftB 4268213 c.624T>C synonymous_variant 0.46 ethambutol
aftB 4268228 c.609C>G synonymous_variant 0.5 ethambutol
aftB 4268233 p.Ile202Val missense_variant 0.5 ethambutol Uncertain significance
aftB 4268236 c.601T>C synonymous_variant 0.5 ethambutol
aftB 4268952 c.-116G>A upstream_gene_variant 0.86 ethambutol
ubiA 4268956 p.Ala293Gly missense_variant 0.83 ethambutol
aftB 4268978 c.-142C>T upstream_gene_variant 0.78 ethambutol
aftB 4268994 c.-158T>C upstream_gene_variant 0.86 ethambutol
aftB 4269000 c.-164G>A upstream_gene_variant 0.88 ethambutol
aftB 4269006 c.-170T>C upstream_gene_variant 0.91 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.9 ethambutol
aftB 4269027 c.-191C>G upstream_gene_variant 0.85 ethambutol
aftB 4269030 c.-194C>G upstream_gene_variant 0.77 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 0.76 ethambutol
aftB 4269045 c.-209G>C upstream_gene_variant 0.69 ethambutol
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 0.72 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 0.6 ethambutol
ubiA 4269131 c.703C>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
ubiA 4269139 p.Cys232Ser missense_variant 0.73 ethambutol Uncertain significance
ubiA 4269143 p.Leu231Val missense_variant 0.79 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.79 ethambutol Not assoc w R - Interim
aftB 4269150 c.-314G>C upstream_gene_variant 0.82 ethambutol
ubiA 4269162 c.670_672delTTGinsCC frameshift_variant&missense_variant 0.75 ethambutol
ubiA 4269177 c.657G>A synonymous_variant 0.72 ethambutol Not assoc w R - Interim
aftB 4269180 c.-344G>T upstream_gene_variant 0.72 ethambutol
aftB 4269195 c.-359C>T upstream_gene_variant 0.78 ethambutol
aftB 4269216 c.-380C>T upstream_gene_variant 0.74 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.71 ethambutol Not assoc w R - Interim
ubiA 4269225 c.609C>T synonymous_variant 0.7 ethambutol Not assoc w R - Interim
aftB 4269231 c.-395C>T upstream_gene_variant 0.72 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 0.71 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.69 ethambutol
aftB 4269248 c.-412C>T upstream_gene_variant 0.68 ethambutol
aftB 4269261 c.-425G>A upstream_gene_variant 0.65 ethambutol
aftB 4269723 c.-887G>C upstream_gene_variant 0.77 ethambutol
aftB 4269744 c.-908G>C upstream_gene_variant 0.68 ethambutol
aftB 4269762 c.-926C>G upstream_gene_variant 0.68 ethambutol
ubiA 4269771 p.Ile21Met missense_variant 0.69 ethambutol
ethA 4326298 c.1176G>A synonymous_variant 0.5 ethionamide
ethA 4326304 c.1170C>G synonymous_variant 0.48 ethionamide
ethA 4326322 c.1152T>C synonymous_variant 0.52 ethionamide
ethA 4326331 c.1143C>G synonymous_variant 0.54 ethionamide
ethA 4326337 c.1137C>T synonymous_variant 0.54 ethionamide Not assoc w R - Interim
ethA 4326343 c.1131C>T synonymous_variant 0.57 ethionamide
ethA 4326346 c.1128C>G synonymous_variant 0.59 ethionamide
ethA 4326352 c.1122T>G synonymous_variant 0.62 ethionamide
ethA 4326469 c.1005T>C synonymous_variant 0.69 ethionamide
ethA 4326475 c.999G>T synonymous_variant 0.68 ethionamide
ethA 4326481 c.993C>T synonymous_variant 0.65 ethionamide Not assoc w R - Interim
ethA 4326484 c.990T>A synonymous_variant 0.68 ethionamide
ethA 4326487 c.987A>C synonymous_variant 0.65 ethionamide
ethA 4326490 c.984C>T synonymous_variant 0.65 ethionamide
ethA 4326507 p.Thr323Ser missense_variant 0.75 ethionamide
ethA 4326510 p.Ala322Pro missense_variant 0.76 ethionamide
ethA 4326520 p.Glu318Asp missense_variant 0.77 ethionamide
ethA 4326523 c.951T>C synonymous_variant 0.79 ethionamide
ethA 4326535 c.939G>C synonymous_variant 0.78 ethionamide
ethR 4326556 c.-993A>G upstream_gene_variant 0.82 ethionamide
ethA 4326563 p.Ala304Gly missense_variant 0.78 ethionamide
ethR 4326565 c.-984C>A upstream_gene_variant 0.79 ethionamide
ethR 4326591 c.-958A>G upstream_gene_variant 0.82 ethionamide
ethA 4326598 c.876A>G synonymous_variant 0.82 ethionamide Not assoc w R - Interim
ethR 4326610 c.-939G>C upstream_gene_variant 0.8 ethionamide
ethR 4326613 c.-936G>A upstream_gene_variant 0.79 ethionamide
ethR 4326628 c.-921G>A upstream_gene_variant 0.75 ethionamide
ethR 4326637 c.-912T>G upstream_gene_variant 0.71 ethionamide
ethR 4326640 c.-909C>T upstream_gene_variant 0.64 ethionamide
ethA 4326874 p.Lys200Asn missense_variant 0.73 ethionamide
ethR 4326880 c.-669G>A upstream_gene_variant 0.82 ethionamide
ethR 4326886 c.-663G>A upstream_gene_variant 0.82 ethionamide
ethA 4326895 c.579G>A synonymous_variant 0.84 ethionamide Not assoc w R - Interim
ethR 4326901 c.-648C>A upstream_gene_variant 0.86 ethionamide
ethR 4326907 c.-642C>A upstream_gene_variant 0.86 ethionamide
ethR 4326913 c.-636C>G upstream_gene_variant 0.83 ethionamide
ethR 4326919 c.-630T>G upstream_gene_variant 0.83 ethionamide
ethR 4326928 c.-621G>T upstream_gene_variant 0.86 ethionamide
ethA 4326949 p.Ala175Gly missense_variant 0.8 ethionamide
ethA 4326952 p.Asp174Glu missense_variant 0.8 ethionamide
ethA 4327296 p.Tyr60His missense_variant 0.42 ethionamide
ethR 4327300 c.-249G>A upstream_gene_variant 0.5 ethionamide
ethR 4327306 c.-243G>A upstream_gene_variant 0.55 ethionamide
ethR 4327318 c.-231T>G upstream_gene_variant 0.71 ethionamide
ethR 4327327 c.-222A>G upstream_gene_variant 0.72 ethionamide
ethR 4327330 c.-219G>A upstream_gene_variant 0.73 ethionamide
ethR 4327335 c.-214A>G upstream_gene_variant 0.71 ethionamide
ethR 4327336 c.-213A>G upstream_gene_variant 0.68 ethionamide
ethA 4327356 p.Ser40Ala missense_variant 0.72 ethionamide
ethA 4327357 p.Glu39Ser missense_variant 0.7 ethionamide
ethR 4327390 c.-159C>G upstream_gene_variant 0.74 ethionamide
ethR 4327396 c.-153A>G upstream_gene_variant 0.74 ethionamide
ethR 4327408 c.-141G>A upstream_gene_variant 0.64 ethionamide
ethR 4327423 c.-126G>C upstream_gene_variant 0.53 ethionamide
ethR 4327426 c.-123A>G upstream_gene_variant 0.53 ethionamide
ethR 4327432 c.-117G>A upstream_gene_variant 0.57 ethionamide
ethA 4327671 c.-198C>G upstream_gene_variant 0.46 ethionamide
ethA 4327680 c.-207A>G upstream_gene_variant 0.58 ethionamide
ethA 4327695 c.-222A>G upstream_gene_variant 0.68 ethionamide
ethA 4327707 c.-234G>C upstream_gene_variant 0.63 ethionamide
ethA 4327710 c.-237G>T upstream_gene_variant 0.63 ethionamide
ethA 4327713 c.-240A>T upstream_gene_variant 0.61 ethionamide
ethA 4327716 c.-243G>T upstream_gene_variant 0.59 ethionamide
ethA 4327720 c.-247T>G upstream_gene_variant 0.59 ethionamide
ethA 4327765 c.-292G>A upstream_gene_variant 0.54 ethionamide
ethA 4327770 c.-297G>C upstream_gene_variant 0.52 ethionamide
ethA 4327782 c.-309C>A upstream_gene_variant 0.4 ethionamide
ethA 4328088 c.-615C>T upstream_gene_variant 0.38 ethionamide
ethR 4328097 c.549G>A synonymous_variant 0.5 ethionamide Not assoc w R - Interim
ethA 4328106 c.-633T>G upstream_gene_variant 0.54 ethionamide
ethR 4328114 p.Gly189Ala missense_variant 0.59 ethionamide
ethR 4328126 p.Ser193Cys missense_variant 0.59 ethionamide
ethA 4328130 c.-657C>T upstream_gene_variant 0.57 ethionamide
ethA 4328136 c.-663T>C upstream_gene_variant 0.59 ethionamide
ethA 4328139 c.-666G>C upstream_gene_variant 0.57 ethionamide
ethR 4328141 p.Arg198His missense_variant 0.57 ethionamide
ethA 4328151 c.-678A>G upstream_gene_variant 0.5 ethionamide
ethA 4328172 c.-699C>G upstream_gene_variant 0.57 ethionamide
ethR 4328174 p.Thr209Ser missense_variant 0.52 ethionamide
ethA 4328181 c.-708A>G upstream_gene_variant 0.42 ethionamide