TB-Profiler result

Run: ERR4769452

Summary

Run ID: ERR4769452

Sample name:

Date: 2024-04-15T01:58:36.164898

Number of reads: 418497

Percentage reads mapped: 18.28

Median coverage: 2.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.06
lineage4 Euro-American None 0.97
lineage4.9 Euro-American (H37Rv-like) None 0.95
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ofloxacin
levofloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrB 6738 p.Thr500Asn missense_variant 0.88 moxifloxacin Uncertain significance Mutation from literature
levofloxacin Uncertain significance Mutation from literature
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.92 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 717 c.717C>T synonymous_variant 1.0 isoniazid
dnaA 720 c.720G>A synonymous_variant 1.0 isoniazid
dnaA 723 c.723A>G synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 1.0 isoniazid
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 798 c.798C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 864 c.864C>T synonymous_variant 1.0 isoniazid
gyrB 6170 p.His311Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6202 c.963C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6203 c.964_966delAGCinsTCG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6229 c.990G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6271 c.1032C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6310 c.-992G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6688 c.-614C>A upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6727 c.1488G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6730 c.-572A>G upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.95 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6841 c.1602T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6869 c.1630_1632delTTGinsCT frameshift_variant&synonymous_variant 0.92 levofloxacin Uncertain significance
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6878 c.1639_1641delTTGinsCA frameshift_variant&missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin
gyrB 6881 c.1642T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7078 c.-224A>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7096 c.-206G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 7222 c.1983C>T synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7335 c.34_36delCTCinsGG frameshift_variant&missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 7340 p.Asp13Glu missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7613 c.312G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7637 c.336C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7673 c.372G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 7758 c.457_459delATCinsGT frameshift_variant&missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7778 c.477G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7942 p.Glu214Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7951 p.Ala217Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7958 c.657C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7970 c.669T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7973 c.672A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7988 c.687G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7992 p.Ala231Ser missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7997 c.696A>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8000 c.699G>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8309 c.1008G>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8438 c.1137C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8649 p.Arg450Lys missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>T synonymous_variant 0.95 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8761 p.Val487Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8769 p.His490Tyr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8804 c.1503C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8813 p.Asp504Glu missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8930 c.1629C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9227 c.1926C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9266 p.Asp655Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9647 c.2346C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9683 c.2382G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9686 c.2385A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491259 c.477T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491307 c.525C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491382 c.600G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491415 c.633A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491417 p.Arg212Leu missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491421 p.Glu213Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491427 c.645C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491430 c.648T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491433 c.651C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491436 c.654T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491439 p.Asp219Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491442 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491443 p.Ser221Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491447 p.Val222Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491454 c.672C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491535 c.753G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491668 p.Lys296Gln missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491685 c.903G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 0.83 clofazimine
pretomanid
delamanid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575714 p.Tyr123Asn missense_variant 1.0 ethionamide
isoniazid
mshA 575725 c.378C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575751 p.Gly135Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575761 c.414C>T synonymous_variant 0.97 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575840 c.494dupC frameshift_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575844 c.498delC frameshift_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575848 c.501C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575851 c.504C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575892 p.Ala182Gly missense_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575916 p.Asp190Ala missense_variant 1.0 ethionamide
isoniazid
ccsA 620670 c.780C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620707 c.817_819delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620758 p.Arg290Tyr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620800 p.Val304Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657708 c.-238C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657724 c.-254A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657730 c.-260A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
nusG 734421 c.168A>C synonymous_variant 0.93 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.93 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.95 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.95 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.96 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.96 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734544 c.291C>T synonymous_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.92 rifampicin
nusG 734787 c.534T>G synonymous_variant 0.92 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.93 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.93 rifampicin
nusG 734820 c.567A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 0.95 rifampicin
nusG 734841 c.588G>A synonymous_variant 0.94 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.89 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.95 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.94 rifampicin
nusG 734859 c.606G>C synonymous_variant 0.94 rifampicin
nusG 734863 p.Thr204Ser missense_variant 0.94 rifampicin
nusG 734889 c.636G>A synonymous_variant 0.94 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.94 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734922 c.669C>T synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760148 p.Asp114Glu missense_variant 1.0 rifampicin
rpoB 760155 p.Lys117Arg missense_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.96 rifampicin
rpoB 760178 c.372G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>G synonymous_variant 0.96 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 0.97 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.96 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.96 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>C synonymous_variant 1.0 rifampicin
rpoB 760354 p.Glu183Ala missense_variant 1.0 rifampicin
rpoB 760357 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760389 c.583_585delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760418 c.612G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760449 p.Thr215Leu missense_variant 0.93 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760527 c.721_727delCAGATTGinsGCCA missense_variant&disruptive_inframe_deletion 0.95 rifampicin
rpoB 760535 c.729_730insCGG conservative_inframe_insertion 0.95 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.97 rifampicin Uncertain significance
rpoB 760587 p.Thr261Ala missense_variant 0.97 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760593 p.Gly263Asn missense_variant 1.0 rifampicin
rpoB 760596 p.Thr264Ser missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>G synonymous_variant 0.94 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.94 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.88 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.94 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.98 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.98 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.98 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.98 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.96 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 0.98 rifampicin
rpoB 761189 c.1383T>G synonymous_variant 0.96 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.96 rifampicin
rpoB 761204 c.1398C>T synonymous_variant 0.96 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.96 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 0.93 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 0.89 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.94 rifampicin
rpoB 761289 p.Ser495Ala missense_variant 0.93 rifampicin
rpoB 761292 p.Val496Thr missense_variant 0.93 rifampicin
rpoB 761297 c.1491C>T synonymous_variant 0.93 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 0.95 rifampicin
rpoB 761347 p.Val514Ala missense_variant 0.93 rifampicin
rpoB 761350 p.Asp515Gly missense_variant 0.93 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.93 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.92 rifampicin
rpoB 761366 c.1560C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761373 p.Val523His missense_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761430 c.1624_1626delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761435 p.Asp543Glu missense_variant 1.0 rifampicin
rpoB 761437 p.Ala544Gly missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.85 rifampicin
rpoB 761452 p.Val549Ala missense_variant 0.95 rifampicin
rpoB 761457 p.Pro551Glu missense_variant 0.94 rifampicin
rpoB 761462 c.1656C>G synonymous_variant 0.95 rifampicin
rpoB 761465 c.1659G>T synonymous_variant 0.95 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 0.96 rifampicin
rpoB 761482 p.Ala559Gly missense_variant 0.96 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.96 rifampicin
rpoB 761502 c.1696_1698delCCCinsTG frameshift_variant&missense_variant 0.96 rifampicin
rpoB 761508 p.Ser568Asp missense_variant 0.92 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 0.97 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.94 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.97 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.97 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>G synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 1.0 rifampicin
rpoB 761712 p.Val636Ile missense_variant 1.0 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 1.0 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761728 p.Ser641Thr missense_variant 1.0 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>G synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761789 c.1983G>C synonymous_variant 1.0 rifampicin
rpoB 761791 p.Arg662Gln missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761814 p.Ala670Asn missense_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 1.0 rifampicin
rpoB 761879 p.Glu691Asp missense_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761897 c.2091C>G synonymous_variant 0.96 rifampicin
rpoB 761903 c.2097T>C synonymous_variant 0.95 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.95 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.89 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.94 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.95 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.95 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762006 c.2200_2202delCGCinsAG frameshift_variant&missense_variant 0.97 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762024 p.Val740Thr missense_variant 0.98 rifampicin Uncertain significance
rpoB 762029 c.2223C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>A synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 0.98 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762281 c.2475G>A synonymous_variant 0.97 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762299 c.2493G>T synonymous_variant 0.96 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.95 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.97 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.97 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.97 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.96 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 0.96 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.95 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.95 rifampicin
rpoC 762407 c.-963G>C upstream_gene_variant 0.95 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.96 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.96 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.91 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 1.0 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 762768 p.Pro988Ala missense_variant 1.0 rifampicin Uncertain significance
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 762795 p.Asp997Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762917 c.-453C>A upstream_gene_variant 0.97 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoB 763203 p.Ser1133Ala missense_variant 1.0 rifampicin Uncertain significance
rpoB 763207 p.Ser1134Lys missense_variant 1.0 rifampicin Uncertain significance
rpoB 763227 c.3421C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763430 c.61A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 0.97 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763447 c.78C>T synonymous_variant 0.97 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 0.97 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>T synonymous_variant 1.0 rifampicin
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763657 c.288G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 1.0 rifampicin
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.94 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.93 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.91 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763972 c.603C>T synonymous_variant 0.95 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.96 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.96 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.96 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764020 c.651C>T synonymous_variant 0.96 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.96 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.96 rifampicin
rpoC 764030 p.Asp221Asn missense_variant 0.96 rifampicin Uncertain significance
rpoC 764039 p.Ser224Asp missense_variant 0.96 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.96 rifampicin
rpoC 764048 p.Thr227Val missense_variant 0.96 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.97 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.93 rifampicin
rpoC 764085 p.Asn239Thr missense_variant 0.83 rifampicin Uncertain significance
rpoC 764087 p.Leu240Val missense_variant 0.93 rifampicin Uncertain significance
rpoC 764098 c.729A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764134 c.765C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.98 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Thr missense_variant 0.98 rifampicin Uncertain significance
rpoC 764213 p.Arg282Lys missense_variant 0.98 rifampicin Uncertain significance
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 1.0 rifampicin
rpoC 764293 c.924G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764341 c.972G>T synonymous_variant 1.0 rifampicin
rpoC 764347 c.978G>C synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 1.0 rifampicin
rpoC 764429 c.1060C>T synonymous_variant 1.0 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.98 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.98 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 1.0 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>A synonymous_variant 0.98 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>G synonymous_variant 0.98 rifampicin
rpoC 764809 c.1440C>G synonymous_variant 0.98 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.97 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764908 c.1539G>A synonymous_variant 0.97 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.97 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764971 c.1602C>T synonymous_variant 1.0 rifampicin
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.97 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.97 rifampicin
rpoC 765076 c.1707A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765079 c.1710T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.96 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765104 c.1735C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>T synonymous_variant 0.93 rifampicin
rpoC 765253 c.1884C>T synonymous_variant 0.92 rifampicin
rpoC 765277 c.1908G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765280 c.1911G>C synonymous_variant 0.93 rifampicin
rpoC 765281 p.Thr638Asp missense_variant 0.93 rifampicin Uncertain significance
rpoC 765292 c.1923G>T synonymous_variant 0.93 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.93 rifampicin Uncertain significance
rpoC 765303 p.Glu645Ala missense_variant 0.93 rifampicin
rpoC 765305 c.1936_1938delATCinsGG frameshift_variant&missense_variant 0.93 rifampicin
rpoC 765311 p.Ala648Thr missense_variant 0.93 rifampicin Uncertain significance
rpoC 765317 c.1948_1950delCTAinsTG frameshift_variant&stop_gained 0.93 rifampicin
rpoC 765326 c.1957_1959delCACinsGG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.94 rifampicin Uncertain significance
rpoC 765339 p.Gln657Arg missense_variant 1.0 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765404 p.Leu679Thr missense_variant 0.97 rifampicin Uncertain significance
rpoC 765409 c.2040T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765418 c.2049C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765421 c.2052C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765445 c.2076G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765453 p.Ala695Val missense_variant 0.95 rifampicin Uncertain significance
rpoC 765478 c.2109T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765547 c.2178C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.95 rifampicin
rpoC 765553 c.2184C>G synonymous_variant 0.95 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 0.96 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.96 rifampicin
rpoC 765611 p.His748Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 765619 c.2250G>A synonymous_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765662 c.2293_2295delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765718 p.Asp783Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765724 c.2355C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 1.0 rifampicin
rpoC 765742 p.Glu791Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765787 c.2418C>T synonymous_variant 0.98 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.98 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.98 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.96 rifampicin Uncertain significance
rpoC 765904 c.2535C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>G synonymous_variant 0.98 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Gly missense_variant 0.93 rifampicin
rpoC 766061 c.2692_2694delGTCinsAG frameshift_variant&missense_variant 0.91 rifampicin
rpoC 766066 c.2697C>G synonymous_variant 0.9 rifampicin
rpoC 766280 c.2911_2913delAGCinsGG frameshift_variant&missense_variant 0.91 rifampicin
rpoC 766291 c.2922G>C synonymous_variant 0.95 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.96 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766351 c.2982C>G synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 1.0 rifampicin
rpoC 766468 c.3099G>A synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766492 c.3123T>A synonymous_variant 1.0 rifampicin
rpoC 766517 p.Thr1050Ala missense_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766547 p.Arg1060Lys missense_variant 1.0 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766576 c.3207C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766610 p.Ser1081Pro missense_variant 1.0 rifampicin
rpoC 766618 c.3249G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>T synonymous_variant 0.97 rifampicin
rpoC 766696 c.3327G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766702 c.3333G>C synonymous_variant 1.0 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.96 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.95 rifampicin
rpoC 766787 p.Glu1140Gln missense_variant 0.95 rifampicin Uncertain significance
rpoC 766798 c.3429C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 766888 c.3519G>C synonymous_variant 0.95 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.95 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.95 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.95 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.95 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.91 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.95 rifampicin
rpoC 766918 c.3549C>G synonymous_variant 0.95 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 0.96 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 0.96 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767191 c.3822C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>T synonymous_variant 0.83 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767266 c.3897G>C synonymous_variant 0.89 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.86 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.86 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781592 c.33T>C synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781664 c.105C>T synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>G synonymous_variant 0.98 streptomycin
rpsL 781724 c.165G>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781748 c.189C>G synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781763 c.204C>G synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800537 c.-272C>T upstream_gene_variant 0.93 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.91 linezolid
rplC 800558 c.-251G>A upstream_gene_variant 0.92 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.91 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.91 linezolid
rplC 800588 c.-221C>G upstream_gene_variant 0.91 linezolid
rplC 800589 c.-220_-219delAGinsTC upstream_gene_variant 0.91 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.91 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.91 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.91 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.93 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.93 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.93 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.93 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.93 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.96 linezolid
rplC 800700 c.-109C>A upstream_gene_variant 0.96 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.95 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.95 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.95 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.95 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.9 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.85 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.84 linezolid
rplC 801201 c.393C>T synonymous_variant 0.92 linezolid
rplC 801210 c.402T>C synonymous_variant 0.92 linezolid
rplC 801220 p.Ser138Gly missense_variant 0.92 linezolid
rplC 801228 c.420T>C synonymous_variant 0.92 linezolid
rplC 801249 c.441T>G synonymous_variant 0.81 linezolid
rplC 801255 c.447C>T synonymous_variant 0.81 linezolid
rplC 801258 c.450C>G synonymous_variant 0.8 linezolid
rplC 801267 c.459A>C synonymous_variant 0.8 linezolid
rplC 801270 c.462T>C synonymous_variant 0.77 linezolid
rplC 801271 c.463_465delGCCinsTG frameshift_variant&missense_variant 0.77 linezolid
rplC 801276 c.468G>C synonymous_variant 0.77 linezolid
rplC 801279 c.471G>C synonymous_variant 0.71 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.77 linezolid
rplC 801307 c.499_501delGCCinsTG frameshift_variant&missense_variant 0.83 linezolid
rplC 801312 c.504G>C synonymous_variant 0.82 linezolid
rplC 801324 c.516T>C synonymous_variant 0.8 linezolid
fbiC 1303488 c.558G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303500 c.570C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303536 c.606G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303596 c.666G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304845 p.Ala639Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304857 p.Thr643Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304874 c.1944C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304904 c.1974G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304918 p.Thr663Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305189 c.2259G>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305197 p.Ala756Gly missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305216 c.2286C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305219 c.2289T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
sigE 1364872 p.Ile154Val missense_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364895 p.Glu161Asp missense_variant 1.0 pyrazinamide
sigE 1364901 c.489C>T synonymous_variant 1.0 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364926 c.514_516delAACinsGT frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364952 c.540A>C synonymous_variant 1.0 pyrazinamide
sigE 1364960 p.Gly183Asp missense_variant 0.96 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>G synonymous_variant 1.0 pyrazinamide
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364992 p.Pro194Ala missense_variant 1.0 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
sigE 1365006 c.594T>G synonymous_variant 1.0 pyrazinamide
sigE 1365009 c.597C>G synonymous_variant 1.0 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365045 c.633C>T synonymous_variant 1.0 pyrazinamide
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472017 n.172C>T non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472292 n.447A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453delGinsCT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472300 n.455C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470delTinsGG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838_839insTA non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445delCinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473791 n.134A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473812 n.155G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473828 n.171_175delGGTGCinsCCGGTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474016 n.359C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474026 n.369C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474104 n.448_450delTAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474110 n.454_455insGTTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474288 n.631delCinsTCT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474708 n.1052dupG non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474711 n.1054_1055insA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474715 n.1061delA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475246 n.1589_1590insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475249 n.1594_1598delACTCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475265 n.1608_1611delGTGTinsTGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475272 n.1615G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475278 n.1621delGinsCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475297 n.1640C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475482 n.1825A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476108 n.2451T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1673916 c.-286A>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673961 c.-241A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1673967 c.-235G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673973 c.-229G>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673982 c.-220G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673985 c.-217C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 0.8 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674601 p.Leu134Thr missense_variant 0.9 ethionamide
isoniazid
inhA 1674610 c.409_411delATCinsGG frameshift_variant&missense_variant 0.9 ethionamide
isoniazid
inhA 1674621 c.420C>G synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674639 c.438C>G synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674699 c.498C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674702 c.501G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674732 c.531C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674735 c.534G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674740 c.540_541insCCAC frameshift_variant 1.0 ethionamide
isoniazid
inhA 1674743 c.544_547delTACG frameshift_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674830 p.Glu210Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674837 c.636C>T synonymous_variant 0.97 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674839 p.Ala213Glu missense_variant 0.93 ethionamide
isoniazid
inhA 1674848 p.Gln216Arg missense_variant 0.97 ethionamide
isoniazid Uncertain significance
inhA 1674870 c.669T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 0.97 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674892 p.Asn231Asp missense_variant 0.97 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674900 c.699G>A synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 0.96 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674927 c.726G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674933 c.732G>A synonymous_variant 0.97 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674942 c.741T>G synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674963 c.762G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674970 c.769_770insCGG disruptive_inframe_insertion 0.91 ethionamide
isoniazid
inhA 1674973 p.Ile258Val missense_variant 0.91 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833547 c.6G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833578 p.Val13Ile missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833770 p.Asn77His missense_variant 1.0 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833814 c.273C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834040 p.Lys167Arg missense_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834172 p.Ile211Val missense_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834432 c.891G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834527 p.Arg329Gln missense_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834558 c.1017C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834603 p.Glu354Asp missense_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.97 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834684 c.1143C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834751 c.1210_1212delCTTinsAC frameshift_variant&missense_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834756 c.1215G>A synonymous_variant 0.94 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsAC upstream_gene_variant 0.97 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853474 c.-132C>G upstream_gene_variant 1.0 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853480 c.-126G>C upstream_gene_variant 1.0 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.96 linezolid
tsnR 1853516 c.-90C>G upstream_gene_variant 0.94 linezolid
tsnR 1853523 c.-83_-82delCGinsAA upstream_gene_variant 0.93 linezolid
tsnR 1853528 c.-78G>C upstream_gene_variant 0.93 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 0.93 linezolid
tsnR 1853540 c.-66A>G upstream_gene_variant 0.93 linezolid
tsnR 1853543 c.-63C>T upstream_gene_variant 0.93 linezolid
kasA 2517926 c.-189G>A upstream_gene_variant 1.0 isoniazid
kasA 2518223 c.109T>C synonymous_variant 1.0 isoniazid
kasA 2518240 c.126C>A synonymous_variant 1.0 isoniazid
kasA 2518243 c.129C>T synonymous_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 1.0 isoniazid
kasA 2518282 c.168A>G synonymous_variant 1.0 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 1.0 isoniazid
kasA 2518300 c.186T>G synonymous_variant 1.0 isoniazid
kasA 2518306 c.192C>G synonymous_variant 1.0 isoniazid
kasA 2518315 c.201G>C synonymous_variant 1.0 isoniazid
kasA 2518322 p.Ser70Asp missense_variant 1.0 isoniazid
kasA 2518336 c.222A>G synonymous_variant 1.0 isoniazid
kasA 2518339 c.225C>G synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.97 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.97 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.97 isoniazid
kasA 2518585 c.471G>A synonymous_variant 0.95 isoniazid
kasA 2518588 c.474T>G synonymous_variant 0.97 isoniazid
kasA 2518591 c.477G>T synonymous_variant 0.97 isoniazid
kasA 2518594 c.480C>T synonymous_variant 0.97 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.98 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.98 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.98 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.96 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.96 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.93 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.93 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.93 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.93 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.93 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.98 isoniazid
kasA 2518726 c.612G>A synonymous_variant 0.98 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.98 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.98 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.98 isoniazid
kasA 2518759 c.645C>G synonymous_variant 0.98 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.98 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.97 isoniazid
kasA 2518787 c.673_675delCGGinsGC frameshift_variant&missense_variant 0.97 isoniazid
kasA 2518792 c.678C>G synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518811 p.Asp233Asn missense_variant 1.0 isoniazid
kasA 2518816 c.702C>G synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518834 c.720C>T synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.97 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.96 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.96 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.95 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.93 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.93 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726633 c.441C>G synonymous_variant 1.0 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 1.0 isoniazid
ahpC 2726642 c.450C>G synonymous_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726648 c.456T>A synonymous_variant 1.0 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 1.0 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782491 p.Asn518Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782496 p.Asp516Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782510 c.1533G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782576 c.1467C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782582 c.1461C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783281 c.762G>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783284 c.759G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783373 p.Glu224Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783443 p.Gln200Ala missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783617 c.426G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783646 p.Asp133Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783767 c.276C>T synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783773 c.270A>G synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783837 p.Thr69Ser missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783842 c.201C>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783847 p.Thr66Pro missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783848 c.195C>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783875 p.Lys56Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783926 c.117C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783986 c.57G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784016 p.Lys9Arg missense_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996548 c.-191C>G upstream_gene_variant 0.9 capreomycin
Rv2681 2996554 c.-185A>C upstream_gene_variant 0.9 capreomycin
Rv2681 2996563 c.-176A>C upstream_gene_variant 0.91 capreomycin
Rv2681 2996587 c.-152G>C upstream_gene_variant 0.92 capreomycin
Rv2680 2996592 p.Ala163Gly missense_variant 0.92 capreomycin
Rv2681 2996599 c.-140G>A upstream_gene_variant 0.92 capreomycin
Rv2681 2996600 c.-139C>T upstream_gene_variant 0.92 capreomycin
Rv2681 2996608 c.-131A>G upstream_gene_variant 0.92 capreomycin
Rv2681 2996617 c.-122A>C upstream_gene_variant 0.92 capreomycin
Rv2681 2996635 c.-104C>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996638 p.Asp178Glu missense_variant 1.0 capreomycin
Rv2752c 3065697 c.493_495delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065700 c.492C>G synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065703 c.489A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067427 c.519G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067748 c.198C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067763 c.183C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 1.0 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067847 c.99C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.70_72delCCCinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073950 c.522G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
lpqB 3624674 c.235_237delAACinsGT frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624677 c.234C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624704 c.207G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624710 p.Leu67Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624734 c.177A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624737 c.174C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3625054 c.-144C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625066 c.-156G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625069 c.-159T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625072 c.-162G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625075 c.-165G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625084 c.-174C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Lys missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625111 c.-201G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625138 c.-228C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625174 c.-264C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625177 c.-267C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625204 c.1408_1410delTCGinsGC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625207 c.-297C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625243 c.-333T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625263 p.Tyr451His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625273 c.-363C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625282 c.-372C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625291 p.Glu441Ala missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625313 p.Arg434Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625369 c.-459G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625386 p.Ala410Pro missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625585 c.-675G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625591 c.-681C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625599 p.Met339Leu missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625623 p.Thr331Ser missense_variant 0.96 bedaquiline
rifampicin
mtrB 3625627 p.Asp329Glu missense_variant 0.96 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 0.96 bedaquiline
rifampicin
mtrB 3625648 c.964_966delTATinsCC frameshift_variant&missense_variant 0.97 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625656 c.958T>C synonymous_variant 0.97 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625657 c.-747C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625663 c.-753G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625720 c.-810G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.95 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625804 c.808_810delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625807 c.807C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625837 c.-927C>A upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625852 c.-942A>T upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625864 c.-954T>G upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625882 c.-972G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3625899 p.Val239Leu missense_variant 0.92 bedaquiline
rifampicin
mtrB 3626684 c.-71G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626729 c.619_621delAAGinsCA frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626735 c.-122C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626750 c.-137T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626756 c.-143C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626776 c.-163A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626804 c.-191A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626822 p.Asp176Glu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626843 c.-230G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626852 c.-239G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626858 c.-245A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626881 c.-268C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626891 c.-278G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626907 p.Asn148Ala missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626912 p.Thr146Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626915 c.-302C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626942 c.406_408delGTAinsAC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626995 c.-382C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626999 c.-386G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627026 c.324G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3627056 c.294C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627068 c.282T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627131 p.Ala73Lys missense_variant 0.97 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin
mtrB 3627191 c.-578G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627213 p.Arg46His missense_variant 0.97 bedaquiline
rifampicin
mtrB 3627224 c.-611G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3627233 c.-620T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627247 p.Ile35Val missense_variant 0.95 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627275 c.-662G>A upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3627323 c.25_27delTTGinsCC frameshift_variant&missense_variant 0.92 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ala missense_variant 0.9 bedaquiline
rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.9 rifampicin
rpoA 3877548 c.960C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877553 p.Glu319Gln missense_variant 0.9 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877611 c.895_897delATCinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 1.0 rifampicin
rpoA 3877629 c.879C>G synonymous_variant 1.0 rifampicin
rpoA 3877638 c.870T>G synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 1.0 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877674 c.834C>T synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877689 c.819C>G synonymous_variant 1.0 rifampicin
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 1.0 rifampicin
rpoA 3877710 c.798C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877755 c.753C>T synonymous_variant 1.0 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877788 c.720G>A synonymous_variant 1.0 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877842 c.666A>G synonymous_variant 1.0 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 1.0 rifampicin
rpoA 3877893 c.615C>G synonymous_variant 1.0 rifampicin
rpoA 3877905 c.603A>C synonymous_variant 1.0 rifampicin
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877929 c.577_579delATCinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878109 c.399G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878118 c.390T>C synonymous_variant 0.94 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.94 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.95 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.95 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.97 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>T synonymous_variant 0.97 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.97 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.97 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878394 c.114G>T synonymous_variant 0.97 rifampicin
rpoA 3878400 c.108T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 0.97 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.96 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.96 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.95 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.92 rifampicin
rpoA 3878725 c.-218A>T upstream_gene_variant 1.0 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878758 c.-251G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878775 c.-268A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878785 c.-278T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878830 c.-325_-323delCTGinsAC upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878843 c.-337_-336delCGinsAA upstream_gene_variant 1.0 rifampicin
rpoA 3878845 c.-338G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878873 c.-366G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878887 c.-382_-380delAACinsGT upstream_gene_variant 1.0 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 1.0 rifampicin
rpoA 3878899 c.-392C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879097 c.-590C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879125 c.-618T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879178 c.-671T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879190 c.-683C>A upstream_gene_variant 1.0 rifampicin
rpoA 3879199 c.-692C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 1.0 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.96 delamanid
pretomanid
ddn 3986661 c.-183_-179delCAGAGinsT upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.94 delamanid
pretomanid
clpC1 4038563 c.2142C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038587 c.2118C>T synonymous_variant 0.89 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.89 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038611 c.2094C>T synonymous_variant 0.91 pyrazinamide
clpC1 4038620 p.Gln695Leu missense_variant 0.92 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.96 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.95 pyrazinamide
clpC1 4038650 c.2055C>T synonymous_variant 0.95 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.94 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.94 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.96 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038698 c.2007C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038726 p.Thr660Cys missense_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038794 c.1909_1911delAGCinsTCG synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.98 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038995 c.1708_1710delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039001 c.1702_1704delAACinsGG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039127 p.Lys526Ala missense_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039141 p.Glu522Lys missense_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039271 c.1434G>A synonymous_variant 0.96 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039328 c.1377A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.98 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.97 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039472 c.1233G>T synonymous_variant 0.97 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039487 c.1218G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039581 p.Thr375Ser missense_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039694 c.1011G>A synonymous_variant 0.97 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039727 c.978C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039733 c.972G>T synonymous_variant 0.97 pyrazinamide
clpC1 4039736 c.969C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039754 c.951G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039855 c.850C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040001 p.His235Ala missense_variant 0.96 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040135 c.570C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040165 c.540G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040213 c.492T>A synonymous_variant 0.97 pyrazinamide
clpC1 4040225 c.480A>T synonymous_variant 0.98 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040234 c.471C>A synonymous_variant 0.98 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.98 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.97 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 0.96 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040303 c.402G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040315 p.Glu130Asp missense_variant 0.97 pyrazinamide
clpC1 4040318 c.387C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040321 c.384C>T synonymous_variant 0.98 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.98 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.98 pyrazinamide
clpC1 4040456 c.249C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040465 c.240T>C synonymous_variant 0.98 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040513 c.192G>A synonymous_variant 0.98 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.98 pyrazinamide
clpC1 4040540 c.165G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040615 c.90C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.94 pyrazinamide
clpC1 4040645 c.60C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040660 c.45G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040669 c.36C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040681 c.24T>G synonymous_variant 0.95 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.89 pyrazinamide
clpC1 4040708 c.-4A>G upstream_gene_variant 0.82 pyrazinamide
glpK 4138547 c.1209C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138550 c.1206C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>A synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138655 c.1101G>A synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138661 c.1095T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138664 c.1092G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138667 c.1089G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138685 c.1071C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240717 c.855T>C synonymous_variant 0.92 ethambutol
embC 4240736 c.874_875delTCinsAG synonymous_variant 0.93 ethambutol
embC 4240765 c.903C>G synonymous_variant 0.91 ethambutol
embC 4240768 c.906G>C synonymous_variant 0.9 ethambutol
embC 4240769 c.907_909delGTGinsAC frameshift_variant&missense_variant 0.9 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.9 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.9 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.9 ethambutol
embC 4240800 p.Tyr313Phe missense_variant 0.91 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.91 ethambutol
embC 4240822 c.960C>G synonymous_variant 0.91 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.93 ethambutol
embC 4240843 c.981C>T synonymous_variant 0.93 ethambutol
embC 4240859 p.Leu333Val missense_variant 0.9 ethambutol
embC 4241071 c.1209C>G synonymous_variant 1.0 ethambutol
embC 4241084 p.Leu408Ala missense_variant 1.0 ethambutol
embC 4241104 c.1242G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241134 c.1272G>A synonymous_variant 1.0 ethambutol
embC 4241135 p.Val425Leu missense_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241141 p.Ile427Val missense_variant 1.0 ethambutol Uncertain significance
embC 4241158 c.1296T>C synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241167 c.1305C>G synonymous_variant 1.0 ethambutol
embC 4241185 c.1323G>C synonymous_variant 1.0 ethambutol
embC 4241188 c.1326C>G synonymous_variant 1.0 ethambutol
embC 4241197 c.1335G>C synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>C synonymous_variant 1.0 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.9 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.92 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.92 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.92 ethambutol
embC 4241591 p.Leu577Ile missense_variant 0.92 ethambutol
embC 4241608 c.1746C>G synonymous_variant 0.92 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.92 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.92 ethambutol
embC 4241623 c.1761C>G synonymous_variant 0.92 ethambutol
embC 4241644 c.1782G>C synonymous_variant 1.0 ethambutol
embC 4241648 c.1786T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241659 c.1797G>A synonymous_variant 1.0 ethambutol
embA 4242826 c.-407G>C upstream_gene_variant 1.0 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 1.0 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 1.0 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 1.0 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 1.0 ethambutol
embA 4242868 c.-365C>G upstream_gene_variant 1.0 ethambutol
embA 4242871 c.-362C>G upstream_gene_variant 1.0 ethambutol
embC 4242872 p.Asp1004Thr missense_variant 1.0 ethambutol
embC 4242878 p.Thr1006Val missense_variant 1.0 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 1.0 ethambutol
embA 4242922 c.-311C>G upstream_gene_variant 0.96 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embA 4242940 c.-293T>C upstream_gene_variant 0.95 ethambutol
embC 4242941 p.His1027Asn missense_variant 0.95 ethambutol
embA 4242946 c.-287T>C upstream_gene_variant 0.95 ethambutol
embA 4242952 c.-281T>C upstream_gene_variant 0.95 ethambutol
embA 4242955 c.-278C>G upstream_gene_variant 0.95 ethambutol
embA 4244814 p.Leu528Met missense_variant 1.0 ethambutol
embA 4244821 p.Gly530Ala missense_variant 1.0 ethambutol
embA 4244823 p.Val531Met missense_variant 1.0 ethambutol
embA 4244829 c.1597_1599delTTCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244849 c.1617C>G synonymous_variant 1.0 ethambutol
embA 4244853 c.1621_1623delGTGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244856 c.1624_1626delGCGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244862 p.Leu544Val missense_variant 1.0 ethambutol
embA 4244885 c.1653A>G synonymous_variant 1.0 ethambutol
embA 4244894 c.1662C>G synonymous_variant 1.0 ethambutol
embA 4244895 c.1663_1665delACTinsTC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244900 c.1668G>C synonymous_variant 1.0 ethambutol
embA 4244906 c.1674C>G synonymous_variant 1.0 ethambutol
embA 4244919 c.1687_1689delCTCinsTG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244930 c.1698G>C synonymous_variant 1.0 ethambutol
embA 4244933 c.1701A>G synonymous_variant 1.0 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.91 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.93 ethambutol
embB 4247462 c.949_950delTCinsAG synonymous_variant 0.94 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.95 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247536 c.1023C>G synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247543 c.1030_1031delAGinsTC synonymous_variant 1.0 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247555 c.1042_1044delCTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247563 p.Met350Ile missense_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247567 c.1054C>T synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>G synonymous_variant 1.0 ethambutol
embB 4247576 c.1063C>T synonymous_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247609 c.1096_1098delTCGinsAGC synonymous_variant 1.0 ethambutol
embB 4247614 c.1101T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247620 c.1107G>C synonymous_variant 1.0 ethambutol
embB 4247630 p.Leu373Phe missense_variant 1.0 ethambutol
embB 4247635 c.1122G>T synonymous_variant 1.0 ethambutol
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
embB 4247945 c.1432T>C synonymous_variant 0.91 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.87 ethambutol
embB 4247957 c.1444_1446delATGinsCA frameshift_variant&missense_variant 0.89 ethambutol
embB 4247971 c.1458C>G synonymous_variant 0.92 ethambutol
embB 4247972 p.Thr487Ala missense_variant 0.92 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.91 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.91 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.9 ethambutol
embB 4248052 c.1539G>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4248055 c.1542G>C synonymous_variant 0.91 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.92 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.92 ethambutol
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248118 c.1605T>C synonymous_variant 1.0 ethambutol
embB 4248139 c.1626C>A synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248149 p.Thr546Cys missense_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248173 p.Val554Met missense_variant 1.0 ethambutol
embB 4248190 c.1677G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248199 c.1686A>G synonymous_variant 1.0 ethambutol
embB 4248202 c.1689T>C synonymous_variant 1.0 ethambutol
embB 4248203 p.Pro564Ala missense_variant 1.0 ethambutol
embB 4248206 c.1693_1695delAGCinsGG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248215 p.Arg568Ser missense_variant 1.0 ethambutol
embB 4248220 c.1707A>C synonymous_variant 1.0 ethambutol
embB 4248225 p.Ala571Val missense_variant 1.0 ethambutol Uncertain significance
embB 4248244 c.1731C>G synonymous_variant 1.0 ethambutol
embB 4248248 c.1735_1737delTTCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.92 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.92 ethambutol
embB 4248264 p.Phe584Ser missense_variant 0.92 ethambutol
embB 4248275 c.1762_1764delACGinsGC frameshift_variant&missense_variant 0.92 ethambutol
embB 4248298 c.1785C>T synonymous_variant 0.9 ethambutol