TB-Profiler result

Run: SRR6045785

Summary

Run ID: SRR6045785

Sample name:

Date: 2024-05-20T09:05:42.882340

Number of reads: 649803

Percentage reads mapped: 18.79

Median coverage: 12.0

Strain: lineage4.2;lineage4.8.1;lineage4.9

Spoligotype:

Drug-resistance: MDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.1
lineage4.4.1.2 Euro-American None 0.06
lineage4.2 Euro-American None 0.23
lineage4 Euro-American None 0.87
lineage4.8.1 Euro-American (mainly T) RD219 0.1
lineage4.9 Euro-American (H37Rv-like) None 0.88
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG p.Ile335Thr Mutation from literature
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.391_393delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.487_488insAT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.491_492delAA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.538_540delCGTinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.952_954delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1573_1575delCTGinsTA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1825_1827delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2512_2514delGAAinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.358_360delCAGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.394_396delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303321 c.391_393delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303417 c.487_488insAT frameshift_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303420 c.491_492delAA frameshift_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303468 c.538_540delCGTinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303882 c.952_954delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304503 c.1573_1575delCTGinsTA frameshift_variant&stop_gained 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304755 c.1825_1827delCTAinsTG frameshift_variant&stop_gained 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305442 c.2512_2514delGAAinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155108 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
fbiA 3640900 c.358_360delCAGinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3640936 c.394_396delCTAinsTG frameshift_variant&stop_gained 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 1.0 isoniazid
dnaA 24 c.24C>T synonymous_variant 1.0 isoniazid
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 42 c.42C>T synonymous_variant 1.0 isoniazid
dnaA 690 c.690G>C synonymous_variant 1.0 isoniazid
dnaA 693 c.693A>C synonymous_variant 1.0 isoniazid
dnaA 702 c.702C>G synonymous_variant 1.0 isoniazid
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 711 c.711C>G synonymous_variant 1.0 isoniazid
dnaA 714 c.714C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 753 c.753C>T synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 759 c.759C>T synonymous_variant 1.0 isoniazid
dnaA 762 c.762C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 768 c.768C>T synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 789 c.789C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 798 c.798C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 804 c.804G>C synonymous_variant 1.0 isoniazid
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>G synonymous_variant 1.0 isoniazid
dnaA 912 c.912T>G synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 945 c.945G>A synonymous_variant 1.0 isoniazid
dnaA 955 c.955A>C synonymous_variant 1.0 isoniazid
dnaA 960 c.960C>G synonymous_variant 1.0 isoniazid
dnaA 963 c.963C>G synonymous_variant 1.0 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.98 isoniazid
dnaA 975 c.975G>C synonymous_variant 1.0 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 1.0 isoniazid
dnaA 993 c.993A>G synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>T synonymous_variant 1.0 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 1.0 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 1.0 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1059 c.1059C>A synonymous_variant 1.0 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 1.0 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1134 c.1134G>C synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 1.0 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 1.0 isoniazid
dnaA 1180 c.1180C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1195 c.1195_1197delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1215 c.1215C>T synonymous_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1239 c.1239G>A synonymous_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1260 c.1260C>T synonymous_variant 1.0 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 1.0 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1291 c.1291_1293delCTTinsTA frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1314 c.1314A>G synonymous_variant 1.0 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1332 c.1332A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1369 c.1369_1371delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1374 c.1374G>A synonymous_variant 1.0 isoniazid
dnaA 1375 c.1375_1377delTTGinsCA frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1389 c.1389C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 1.0 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
gyrB 6091 c.852G>C synonymous_variant 0.93 moxifloxacin
levofloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.62 moxifloxacin
levofloxacin
gyrB 6127 c.888G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrB 6133 c.894G>C synonymous_variant 0.33 moxifloxacin
levofloxacin
gyrB 6136 c.897G>A synonymous_variant 0.38 moxifloxacin
levofloxacin Not assoc w R - Interim
gyrB 6151 c.912C>T synonymous_variant 0.54 moxifloxacin
levofloxacin
gyrB 6160 c.921C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrB 6169 c.930C>G synonymous_variant 0.56 moxifloxacin
levofloxacin
gyrB 6190 c.951A>G synonymous_variant 0.41 moxifloxacin
levofloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.41 moxifloxacin
levofloxacin
gyrB 6214 c.975G>C synonymous_variant 0.36 moxifloxacin
levofloxacin
gyrB 6215 c.976_978delTCGinsAC frameshift_variant&missense_variant 0.36 moxifloxacin
levofloxacin Uncertain significance
gyrB 6223 c.984G>C synonymous_variant 0.63 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6250 c.1011A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6259 p.Asp340Glu missense_variant 1.0 moxifloxacin
levofloxacin
gyrB 6266 p.Pro343Ala missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 moxifloxacin
levofloxacin Not assoc w R - Interim
gyrB 6358 c.1119C>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6391 c.1152G>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6418 c.-884C>A upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6440 p.Thr401Ser missense_variant 1.0 moxifloxacin
levofloxacin
gyrB 6445 p.Asp402Glu missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
gyrB 6452 p.Val405Thr missense_variant 0.96 moxifloxacin
levofloxacin
gyrA 6466 c.-836G>A upstream_gene_variant 0.96 moxifloxacin
levofloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6472 c.-830G>A upstream_gene_variant 0.9 moxifloxacin
levofloxacin
gyrA 6475 c.-827C>G upstream_gene_variant 0.91 moxifloxacin
levofloxacin
gyrB 6481 c.1242G>A synonymous_variant 0.92 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 6484 c.-818A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6490 c.-812T>C upstream_gene_variant 0.7 moxifloxacin
levofloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6511 c.-791A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6532 c.-770C>T upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6535 c.-767C>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6541 c.1302C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6542 c.1303_1305delATCinsCG frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin Uncertain significance
gyrB 6550 c.1311A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6559 c.1320C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6613 c.-689A>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.52 moxifloxacin
levofloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6625 c.-677G>A upstream_gene_variant 0.45 moxifloxacin
levofloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.44 moxifloxacin
levofloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.49 moxifloxacin
levofloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6664 c.1425C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin Uncertain significance
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.55 moxifloxacin
levofloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 moxifloxacin
levofloxacin
gyrB 6802 c.1563G>A synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin
gyrB 6824 c.1585C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.97 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6931 c.-371A>T upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6965 c.-337_-335delAGTinsTCG upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 7012 c.1773G>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 7057 c.1818C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 7124 c.1885_1887delTCGinsAC frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin Uncertain significance
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrB 7153 c.1914G>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7186 c.-116C>A upstream_gene_variant 0.95 moxifloxacin
levofloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 1.0 moxifloxacin
levofloxacin
gyrA 7637 c.336C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7683 c.382A>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7706 c.405C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7727 c.426G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 7775 c.474C>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7781 c.480G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7796 c.495G>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 7802 c.501C>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7814 c.513C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7832 c.531G>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 7859 c.558A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8090 c.789C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8099 c.798T>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8156 c.855T>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8165 c.864C>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8186 c.885G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8195 c.894C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8210 c.909G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8234 c.933T>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8240 c.939C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8283 c.982_984delATCinsTG frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8438 c.1137C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8442 c.1141C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8447 c.1146C>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8450 c.1149G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8537 c.1236G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8579 c.1278C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8619 c.1318_1320delTTGinsCA frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8624 c.1323G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8627 c.1326C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8648 c.1347G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8696 c.1395G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8786 c.1485T>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.97 moxifloxacin
levofloxacin
gyrA 8818 p.Ser506Asn missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.97 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8983 p.Cys561Ser missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9029 c.1728T>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9035 c.1734G>A synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9038 c.1737C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9044 c.1743C>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9074 c.1773G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9083 c.1782G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 9161 c.1860C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9164 c.1863G>A synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9182 c.1881T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 9191 c.1890G>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9206 c.1905C>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9209 c.1908G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9233 c.1932C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9239 c.1938C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9248 c.1947G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9251 c.1950G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9266 c.1965C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9267 p.Asn656Gly missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 9287 c.1986G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9293 c.1992G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 9311 c.2010C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9317 c.2016G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9323 c.2022C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9345 c.2044_2046delAGGinsCA frameshift_variant&missense_variant 1.0 moxifloxacin
levofloxacin
gyrA 9374 c.2073G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
fgd1 490800 c.18A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490803 c.21T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490857 c.75C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490875 c.93C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490908 c.126G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491034 c.252C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491055 c.273C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491058 c.276C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491112 c.330G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491623 p.Ala281Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491688 c.906A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491703 c.921C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491704 c.922C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575590 c.243T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575596 c.249C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575634 p.Ala96Val missense_variant 1.0 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575650 c.303G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575651 p.Arg102Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575656 c.309G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575658 p.Ala104Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575680 c.333C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.95 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575860 c.513G>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575887 c.540G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576010 c.663C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576011 c.664_666delAGGinsCA frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576017 p.Val224Leu missense_variant 1.0 ethionamide
isoniazid
mshA 576026 c.679_681delCTTinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576032 p.Gly229Asn missense_variant 1.0 ethionamide
isoniazid
mshA 576045 p.Ala233Gly missense_variant 1.0 ethionamide
isoniazid
mshA 576070 c.723T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576079 c.732G>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619558 c.-333G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619564 c.-327C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619571 c.-320_-319delGTinsAC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-256delTCinsGT upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620238 c.348G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620291 p.Tyr134Phe missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620298 c.408G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620301 c.411G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620676 c.786C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620763 c.873G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620800 p.Val304Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620809 c.919C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 657147 c.324C>T synonymous_variant 1.0 ethionamide
Rv0565c 657161 p.Glu104Gln missense_variant 1.0 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 1.0 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 1.0 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 1.0 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 1.0 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 1.0 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 1.0 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 1.0 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
Rv0565c 657252 c.219G>C synonymous_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657267 c.204G>T synonymous_variant 1.0 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731687 c.-243G>A upstream_gene_variant 0.91 isoniazid
hadA 731698 c.-232_-231insCGAGAGATTTG upstream_gene_variant 0.91 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 0.91 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.91 isoniazid
hadA 731711 c.-219T>A upstream_gene_variant 0.91 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.92 isoniazid
hadA 731742 c.-188A>G upstream_gene_variant 0.95 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.97 isoniazid
hadA 731765 c.-165C>T upstream_gene_variant 0.97 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.97 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.96 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.96 isoniazid
hadA 731798 c.-132C>G upstream_gene_variant 0.96 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.94 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.93 isoniazid
hadA 731989 c.60G>C synonymous_variant 1.0 isoniazid
hadA 732016 c.87C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732018 p.Val30Gly missense_variant 1.0 isoniazid Uncertain significance
hadA 732025 c.96T>G synonymous_variant 1.0 isoniazid
hadA 732028 c.99A>G synonymous_variant 1.0 isoniazid
hadA 732045 p.Tyr39Phe missense_variant 1.0 isoniazid
hadA 732048 p.Phe40Ser missense_variant 1.0 isoniazid
hadA 732052 p.Glu41Asp missense_variant 1.0 isoniazid
hadA 732057 p.Asp43Ala missense_variant 1.0 isoniazid
hadA 732060 p.Gly44Ala missense_variant 1.0 isoniazid
hadA 732064 c.135C>G synonymous_variant 1.0 isoniazid
hadA 732076 c.147G>C synonymous_variant 1.0 isoniazid
hadA 732079 c.150T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732085 c.156C>G synonymous_variant 1.0 isoniazid
hadA 732094 c.165T>C synonymous_variant 1.0 isoniazid
hadA 732103 c.174G>C synonymous_variant 1.0 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732107 p.Ile60Cys missense_variant 1.0 isoniazid
hadA 732115 c.186G>A synonymous_variant 1.0 isoniazid
hadA 732334 c.405G>C synonymous_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732367 c.438C>G synonymous_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732385 c.456A>G synonymous_variant 1.0 isoniazid
hadA 732389 p.Ser154Ala missense_variant 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734111 c.-143A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 1.0 rifampicin
nusG 734118 c.-136_-134delCTTinsTC upstream_gene_variant 1.0 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 1.0 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 1.0 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 1.0 rifampicin
nusG 734173 c.-81_-80delCCinsGA upstream_gene_variant 1.0 rifampicin
nusG 734175 c.-79_-78delGGinsCT upstream_gene_variant 1.0 rifampicin
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734184 c.-70_-68delTTGinsCT upstream_gene_variant 1.0 rifampicin
nusG 734201 c.-53G>C upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 1.0 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 1.0 rifampicin
nusG 734225 c.-29C>T upstream_gene_variant 1.0 rifampicin
nusG 734232 c.-22G>A upstream_gene_variant 1.0 rifampicin
nusG 734233 c.-21T>A upstream_gene_variant 1.0 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 1.0 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734376 p.Glu41Asp missense_variant 1.0 rifampicin
nusG 734383 p.Ser44Arg missense_variant 1.0 rifampicin Uncertain significance
nusG 734387 p.Lys45Arg missense_variant 1.0 rifampicin
nusG 734391 c.138C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734394 c.141C>T synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734415 c.162C>T synonymous_variant 1.0 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734448 c.195C>T synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734505 c.252G>A synonymous_variant 1.0 rifampicin
nusG 734520 c.267C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
rpoB 760058 c.252C>G synonymous_variant 1.0 rifampicin
rpoB 760065 c.259C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760088 c.282C>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760145 c.339C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760403 c.597C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760754 c.948G>C synonymous_variant 1.0 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760796 c.990A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760808 c.1002C>G synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 1.0 rifampicin
rpoB 760877 c.1071G>T synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>T synonymous_variant 0.98 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.98 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>A synonymous_variant 0.98 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.98 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 0.98 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.98 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>T synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.91 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 0.92 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 0.88 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.92 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 0.98 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>G synonymous_variant 1.0 rifampicin
rpoB 761282 c.1476C>T synonymous_variant 0.98 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761373 p.Val523Gln missense_variant 1.0 rifampicin
rpoB 761387 c.1581C>G synonymous_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>T synonymous_variant 1.0 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761439 p.Asp545Ser missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761452 p.Val549Glu missense_variant 1.0 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 1.0 rifampicin
rpoB 761462 c.1656C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761465 c.1659G>C synonymous_variant 1.0 rifampicin
rpoB 761471 c.1665C>T synonymous_variant 1.0 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>A synonymous_variant 1.0 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 1.0 rifampicin
rpoB 761714 c.1908C>G synonymous_variant 1.0 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 1.0 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761816 c.2010C>G synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761867 c.2061C>A synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761955 p.Ile717Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.97 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762368 c.2562G>A synonymous_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>T upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762494 c.-876G>A upstream_gene_variant 1.0 rifampicin
rpoB 762507 c.2701_2703delCTTinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 762524 c.-846G>C upstream_gene_variant 1.0 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoB 762749 c.2943C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762795 c.2989_2991delGACinsAT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762800 c.-570C>G upstream_gene_variant 1.0 rifampicin
rpoC 762812 c.-558C>A upstream_gene_variant 1.0 rifampicin
rpoB 762814 p.Met1003Arg missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762824 c.-546C>T upstream_gene_variant 0.97 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762957 c.3151C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 0.98 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 1.0 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763199 c.-171G>T upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 1.0 rifampicin
rpoC 763211 c.-159C>T upstream_gene_variant 1.0 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 1.0 rifampicin
rpoC 763238 c.-132T>G upstream_gene_variant 1.0 rifampicin
rpoC 763247 c.-123G>A upstream_gene_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 1.0 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 1.0 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763405 c.36C>T synonymous_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763420 c.51G>T synonymous_variant 1.0 rifampicin
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763435 c.66A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.98 rifampicin
rpoC 763618 c.249C>T synonymous_variant 0.98 rifampicin
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.98 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.98 rifampicin
rpoC 763714 c.345G>A synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.98 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.98 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763778 p.Thr137Val missense_variant 1.0 rifampicin
rpoC 763781 p.Ser138Gly missense_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763836 p.Ala156Val missense_variant 0.97 rifampicin
rpoC 763852 c.483C>T synonymous_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>C synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763963 c.594C>G synonymous_variant 1.0 rifampicin
rpoC 763966 c.597C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763967 c.598_600delGGCinsAT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763978 c.609C>T synonymous_variant 1.0 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764015 c.646C>T synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>G synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764212 c.843C>T synonymous_variant 1.0 rifampicin
rpoC 764218 c.849C>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 1.0 rifampicin
rpoC 764248 c.879C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>T synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.97 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764573 c.1204_1206delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.97 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764582 c.1213C>T synonymous_variant 1.0 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.98 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764857 c.1488G>T synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>A synonymous_variant 1.0 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765065 c.1696C>T synonymous_variant 1.0 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>A synonymous_variant 1.0 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765106 c.1737G>C synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765283 c.1914C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765350 p.Ala661Ser missense_variant 1.0 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 1.0 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765571 c.2202C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765578 c.2209C>T synonymous_variant 0.99 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 1.0 rifampicin
rpoC 765592 c.2223C>T synonymous_variant 1.0 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765640 c.2271A>G synonymous_variant 1.0 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 1.0 rifampicin
rpoC 765734 c.2365_2367delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766030 c.2661C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766061 p.Val898Ile missense_variant 1.0 rifampicin
rpoC 766080 c.2712delT frameshift_variant 1.0 rifampicin
rpoC 766084 c.2715_2716insG frameshift_variant 1.0 rifampicin
rpoC 766090 c.2721C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766097 c.2728C>T synonymous_variant 1.0 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766171 c.2802C>T synonymous_variant 1.0 rifampicin
rpoC 766178 p.Ile937Val missense_variant 1.0 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 1.0 rifampicin
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766247 p.Val960Ile missense_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.96 rifampicin
rpoC 766280 c.2911_2913delAGCinsGT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 1.0 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 1.0 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 1.0 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 766469 c.3100C>T synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766923 p.Glu1185Gly missense_variant 1.0 rifampicin
rpoC 766931 c.3562_3564delGCAinsTG frameshift_variant&stop_gained 1.0 rifampicin
rpoC 766936 c.3567G>A synonymous_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767065 c.3696G>C synonymous_variant 1.0 rifampicin
rpoC 767066 c.3697C>T synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>A synonymous_variant 1.0 rifampicin
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
rpoC 767288 c.3919C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767302 c.3933C>A synonymous_variant 1.0 rifampicin
mmpL5 775864 p.Ala873Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775874 c.2607C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsTG frameshift_variant&missense_variant 0.94 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775912 c.2569C>A synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2563_2565delGTTinsAA frameshift_variant&missense_variant 0.66 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775927 c.2554C>T synonymous_variant 0.54 clofazimine
bedaquiline
mmpL5 775937 c.2542_2544delGCGinsTC frameshift_variant&missense_variant 0.5 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775940 c.2541C>T synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.49 clofazimine
bedaquiline
mmpL5 775949 c.2532G>C synonymous_variant 0.46 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.33 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775993 p.Glu830Lys missense_variant 0.8 clofazimine
bedaquiline
mmpL5 775997 c.2484T>G synonymous_variant 0.84 clofazimine
bedaquiline
mmpL5 776003 c.2478C>T synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 776008 p.His825Tyr missense_variant 0.87 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776015 c.2464_2466delATCinsCA frameshift_variant&missense_variant 0.92 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776024 c.2457G>C synonymous_variant 0.97 clofazimine
bedaquiline
mmpL5 776027 c.2454G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776030 c.2451G>A synonymous_variant 0.97 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 0.97 clofazimine
bedaquiline
mmpL5 776056 p.Val809Leu missense_variant 0.97 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776076 p.Ala802Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776084 c.2397C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776093 c.2388C>A synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781601 c.42C>T synonymous_variant 1.0 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781703 c.144G>T synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.98 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.97 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.96 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 1.0 streptomycin
rplC 800225 c.-584T>C upstream_gene_variant 1.0 linezolid
rplC 800231 c.-578C>T upstream_gene_variant 1.0 linezolid
rplC 800252 c.-557C>A upstream_gene_variant 1.0 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 1.0 linezolid
rplC 800278 c.-531_-528delAAGCinsGA upstream_gene_variant 1.0 linezolid
rplC 800287 c.-522G>T upstream_gene_variant 1.0 linezolid
rplC 800292 c.-517C>T upstream_gene_variant 1.0 linezolid
rplC 800295 c.-513_-502delCTTGAAATTGAT upstream_gene_variant 1.0 linezolid
rplC 800311 c.-498_-497insA upstream_gene_variant 1.0 linezolid
rplC 800325 c.-484C>A upstream_gene_variant 1.0 linezolid
rplC 800329 c.-480C>T upstream_gene_variant 1.0 linezolid
rplC 800341 c.-468G>C upstream_gene_variant 1.0 linezolid
rplC 800344 c.-465_-464insG upstream_gene_variant 1.0 linezolid
rplC 800355 c.-454G>A upstream_gene_variant 1.0 linezolid
rplC 800358 c.-450delT upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94_-92delATCinsCT upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 0.97 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 0.97 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.97 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.97 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.96 linezolid
rplC 800844 c.36T>C synonymous_variant 0.85 linezolid
rplC 800856 c.48A>G synonymous_variant 0.88 linezolid
rplC 800865 c.57A>G synonymous_variant 0.87 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.87 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.87 linezolid
rplC 800877 c.69A>C synonymous_variant 0.87 linezolid
rplC 800880 c.72A>G synonymous_variant 0.87 linezolid
rplC 800889 c.81C>T synonymous_variant 0.89 linezolid Not assoc w R - Interim
rplC 800901 c.93C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>C synonymous_variant 1.0 linezolid
rplC 800919 c.111C>G synonymous_variant 1.0 linezolid
rplC 800922 c.114C>G synonymous_variant 1.0 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800939 p.Arg44Leu missense_variant 1.0 linezolid Uncertain significance
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800962 c.154C>T synonymous_variant 1.0 linezolid
rplC 800976 c.168G>A synonymous_variant 1.0 linezolid
rplC 801003 c.195G>C synonymous_variant 1.0 linezolid
rplC 801004 c.196_198delCTGinsGC frameshift_variant&missense_variant 1.0 linezolid
rplC 801009 c.201A>G synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801183 c.375C>A synonymous_variant 1.0 linezolid
rplC 801195 c.387G>T synonymous_variant 1.0 linezolid
rplC 801198 c.390C>T synonymous_variant 1.0 linezolid
rplC 801207 c.399C>T synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>T synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801285 c.477G>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 1.0 linezolid
rplC 801300 c.492C>G synonymous_variant 1.0 linezolid
rplC 801309 c.501C>G synonymous_variant 1.0 linezolid
rplC 801312 c.504G>T synonymous_variant 1.0 linezolid
rplC 801321 c.513C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801349 p.Leu181Val missense_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801363 c.555C>G synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801417 c.609T>C synonymous_variant 1.0 linezolid
Rv1129c 1253587 c.948C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
moxifloxacin
rifampicin Not assoc w R - Interim
levofloxacin
Rv1129c 1253590 c.945A>G synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253602 p.Gly311Glu missense_variant 1.0 isoniazid Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
levofloxacin Uncertain significance
Rv1129c 1253608 c.927G>T synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253614 c.921C>T synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253632 c.903T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
Rv1129c 1253635 c.900C>T synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253638 c.897A>G synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253641 c.892_894delCAGinsGA frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
levofloxacin Uncertain significance
Rv1129c 1253653 c.882T>G synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253665 c.868_870delCGCinsGG frameshift_variant&synonymous_variant 1.0 isoniazid Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
levofloxacin Uncertain significance
Rv1129c 1253683 c.852C>G synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253686 c.849C>A synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253707 c.828A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
moxifloxacin
rifampicin Not assoc w R - Interim
levofloxacin
Rv1129c 1253716 c.819G>C synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253730 p.Ala269Ser missense_variant 1.0 isoniazid Uncertain significance
moxifloxacin
rifampicin Uncertain significance
levofloxacin
Rv1129c 1253743 p.Gln264Arg missense_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253746 c.787_789delGACinsCT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
levofloxacin Uncertain significance
Rv1129c 1253749 c.786T>C synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253766 p.Ser257Ala missense_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253776 c.759C>T synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253779 c.756A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
Rv1129c 1253803 c.732C>G synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253827 c.708A>C synonymous_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
Rv1129c 1253843 p.His231Arg missense_variant 1.0 isoniazid
moxifloxacin
rifampicin
levofloxacin
fbiC 1303233 c.303T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303242 c.312T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303251 c.321C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303272 c.342A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303281 c.351A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303284 c.354T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303285 p.Ser119Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303288 p.Ser120Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303292 p.Thr121Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303297 p.Met123Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303302 c.372A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303314 c.384C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303332 c.402A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303335 c.405T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303341 c.411A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303342 p.Phe138Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303359 c.429G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303374 c.444T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303380 c.450T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303388 p.Ala153Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303392 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303397 p.Arg156Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303399 p.Gln157Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303404 c.474A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303425 c.495G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303431 c.501T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303432 p.Asp168Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303437 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303538 p.Arg203Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303665 c.735G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303680 c.750G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303722 c.792C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303812 c.882C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303844 p.Ala305Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303866 p.Glu312Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303896 c.966G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303938 c.1008C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303977 c.1047C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304019 c.1089C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304070 c.1140C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304077 p.Glu383Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304082 c.1152C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304087 p.Tyr386Phe missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304104 c.1174C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304121 c.1191A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304130 c.1200G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304139 c.1209G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304160 c.1230G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304166 c.1236A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304481 c.1551T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304487 c.1557C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304502 c.1572G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304511 c.1581C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304739 c.1809C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304805 c.1875G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304820 c.1890G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304913 c.1983G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305400 p.His824Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305411 c.2481C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305420 c.2490C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305430 p.Val834Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364793 c.381C>T synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364832 c.420C>G synonymous_variant 1.0 pyrazinamide
sigE 1364835 c.423C>G synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364875 c.463C>A synonymous_variant 1.0 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364892 c.480C>G synonymous_variant 1.0 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 1.0 pyrazinamide
sigE 1364952 c.540A>G synonymous_variant 1.0 pyrazinamide
sigE 1364954 p.Arg181His missense_variant 1.0 pyrazinamide
sigE 1364961 c.549A>T synonymous_variant 1.0 pyrazinamide
sigE 1364962 c.550_552delCCTinsGC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 1.0 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 1.0 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 1.0 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 1.0 pyrazinamide
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin Uncertain significance
capreomycin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin
capreomycin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 kanamycin
amikacin
streptomycin
capreomycin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 kanamycin
amikacin Uncertain significance
streptomycin Uncertain significance
capreomycin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin Uncertain significance
capreomycin Uncertain significance
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 1.0 kanamycin
amikacin
streptomycin
capreomycin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 kanamycin
amikacin
streptomycin
capreomycin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 kanamycin
amikacin
streptomycin
capreomycin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 kanamycin
amikacin
streptomycin
capreomycin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 1.0 kanamycin
amikacin
streptomycin
capreomycin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin
capreomycin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin
capreomycin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin Uncertain significance
capreomycin Uncertain significance
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin Uncertain significance
capreomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin Uncertain significance
capreomycin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin
capreomycin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 kanamycin
amikacin
streptomycin
capreomycin
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin
capreomycin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.38 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476595 n.2938C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476602 n.2945G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673565 c.-637G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673583 c.-619A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673589 c.-613A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673596 c.-606A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673601 c.-601G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673615 c.-587_-586delAAinsTG upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673657 c.-545_-544delCGinsAA upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673660 c.-542C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673697 c.-505G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674069 c.-133G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674079 c.-123C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674083 c.-119_-118delCCinsAG upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674120 c.-82G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>T synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674594 c.393C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674597 c.396G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674612 c.411C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674619 p.Pro140Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674639 c.438C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674645 c.444C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674687 c.486G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674732 c.531C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674745 p.Tyr182Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674774 c.573A>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674837 c.636C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674912 c.711G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674930 c.729C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674963 c.762G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1675002 c.801A>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833532 c.-10A>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1833782 p.Ser81Thr missense_variant 0.99 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>T synonymous_variant 0.99 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833883 c.342C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.92 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834259 c.718_720delCTAinsTG frameshift_variant&stop_gained 0.95 pyrazinamide Uncertain significance
rpsA 1834279 c.738C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834351 c.810G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834405 c.864C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834432 c.891G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide