TB-Profiler result

Run: ERR176568
Summary

Run ID: ERR176568

Sample name:

Date: 2024-04-15T23:34:19.793313

Number of reads: 780263

Percentage reads mapped: 16.86

Median coverage: 13.0

Strain: La3;lineage2.1;lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.2.2 West-Africa 2 RD702 0.07
La1.2.BCG M.bovis None 0.18
lineage2.1 East-Asian (non-Beijing) None 0.07
lineage6.2.3 West-Africa 2 RD702 0.06
lineage4.9 Euro-American (H37Rv-like) None 0.83
La3 M.orygis None 0.09
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2269_2271delGCGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 0.73 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305199 c.2269_2271delGCGinsTC frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance Mutation from literature
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.91 isoniazid Assoc w R High-level resistance
embB 4247448 p.His312Arg missense_variant 0.85 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 549 c.549C>T synonymous_variant 0.57 isoniazid
dnaA 558 c.558G>C synonymous_variant 0.71 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.76 isoniazid
dnaA 597 c.597C>G synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>G synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.81 isoniazid
dnaA 645 c.645A>T synonymous_variant 0.93 isoniazid
dnaA 652 c.652_654delCTAinsTG frameshift_variant&stop_gained 0.9 isoniazid Uncertain significance
dnaA 660 c.660G>C synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.84 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.82 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>A synonymous_variant 0.82 isoniazid
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 0.82 isoniazid Uncertain significance
dnaA 693 c.693A>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 708 c.708T>C synonymous_variant 0.88 isoniazid
dnaA 711 c.711C>G synonymous_variant 0.88 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>T synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 0.92 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.94 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.93 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.9 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.93 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.92 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.86 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.89 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.91 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.91 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.92 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.92 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.89 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.92 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.84 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.92 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.91 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.91 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.96 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.94 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.72 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.71 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.95 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>A synonymous_variant 0.75 isoniazid
dnaA 1029 c.1029C>A synonymous_variant 0.67 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.73 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.8 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1062 c.1062C>A synonymous_variant 0.86 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 1.0 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.8 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.92 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.92 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 0.62 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.86 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.88 isoniazid
dnaA 1146 c.1146C>T synonymous_variant 0.29 isoniazid
dnaA 1149 c.1149C>T synonymous_variant 0.62 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.9 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 0.86 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.6 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.9 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.55 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.64 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 1203 c.1203T>C synonymous_variant 0.3 isoniazid
dnaA 1204 c.1204C>T synonymous_variant 0.67 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.97 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.98 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.95 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.84 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>G synonymous_variant 0.82 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.93 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.84 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.91 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.91 isoniazid
dnaA 1317 c.1317A>C synonymous_variant 0.85 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.65 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>C synonymous_variant 0.8 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 0.53 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.8 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.76 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.69 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.76 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.55 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.8 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.81 isoniazid
dnaA 1413 c.1413A>G synonymous_variant 0.77 isoniazid Not assoc w R - Interim
dnaA 1416 c.1416C>G synonymous_variant 0.84 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.72 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.72 isoniazid
dnaA 1440 c.1440C>T synonymous_variant 0.72 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.88 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.86 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.88 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.8 isoniazid
dnaA 1506 c.1506T>C synonymous_variant 0.75 isoniazid
gyrB 6115 c.876A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.73 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.7 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6262 c.1023G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6355 c.-947G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6397 c.1158G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6403 c.-899T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6412 c.-890G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6457 c.-845T>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6664 c.1425C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6673 c.-629A>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6688 c.-614C>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.73 levofloxacin Uncertain significance
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.96 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 6803 c.-499C>T upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6889 c.-413G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6961 c.-341G>A upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6991 c.-311C>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 7162 c.1923C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7178 c.-124T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7237 c.-65C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7347 p.Glu16Gln missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7445 c.144C>T synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7451 c.150C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7508 c.207C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7577 c.276C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7592 c.291G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7853 c.552C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7871 c.570G>A synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8054 c.753T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8228 c.927G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8337 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.77 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.77 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8369 c.1068G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8492 c.1191G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8537 p.Glu412Asp missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8570 c.1269G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Arg missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8963 c.1662C>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9080 c.1779G>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9110 c.1809G>A synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9122 c.1821C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9134 c.1833C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.91 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9182 c.1881T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9203 c.1902G>A synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9318 c.2017C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9329 c.2028C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9572 c.2271C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9578 c.2277C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.89 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.8 isoniazid
fgd1 490797 c.15G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490858 p.Ala26Thr missense_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490984 c.202C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>T synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491052 c.270C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491070 c.288G>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491083 p.Val101Ile missense_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491088 c.306C>T synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491110 p.Ala110Ser missense_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491124 c.342C>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491160 c.378G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491631 c.849C>T synonymous_variant 0.7 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491646 c.864G>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
mshA 574616 c.-732G>T upstream_gene_variant 0.7 ethionamide
isoniazid
mshA 574619 c.-729C>G upstream_gene_variant 0.69 ethionamide
isoniazid
mshA 574640 c.-708G>C upstream_gene_variant 0.85 ethionamide
isoniazid
mshA 574646 c.-702G>A upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 574655 c.-693C>G upstream_gene_variant 0.84 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 574671 c.-677_-675delGCAinsCTG upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.9 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.9 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574715 c.-633C>G upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 0.91 ethionamide
isoniazid
mshA 575515 c.168G>A synonymous_variant 0.73 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.77 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.86 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575542 c.195C>G synonymous_variant 0.65 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.89 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.63 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.89 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.63 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575587 c.240C>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575618 c.271C>A synonymous_variant 0.59 ethionamide
isoniazid
mshA 575623 c.276C>G synonymous_variant 0.5 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.75 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 0.7 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.7 ethionamide
isoniazid
mshA 575649 p.Val101Glu missense_variant 0.7 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575692 c.345G>C synonymous_variant 0.76 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.92 ethionamide
isoniazid Not assoc w R - Interim
mshA 575705 c.358T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.97 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.86 ethionamide
isoniazid
mshA 575764 c.417C>T synonymous_variant 0.82 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.96 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.86 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.87 ethionamide
isoniazid
mshA 575818 c.471G>T synonymous_variant 0.84 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575824 c.477T>A synonymous_variant 0.85 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.74 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575878 c.531A>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 576193 c.846T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576197 c.850C>T synonymous_variant 0.88 ethionamide
isoniazid
mshA 576202 c.855T>C synonymous_variant 0.88 ethionamide
isoniazid Not assoc w R - Interim
mshA 576211 c.864C>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 576215 c.868T>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 576233 c.886_888delATCinsGG frameshift_variant&missense_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576247 c.900A>G synonymous_variant 0.91 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619528 c.-363C>A upstream_gene_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 619530 c.-360_-358delTCA upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619537 c.-354_-353insTCG upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619618 c.-273C>G upstream_gene_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>G upstream_gene_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>G upstream_gene_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620121 c.231G>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620126 p.Gly79Ala missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620139 c.249C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620141 p.Ala84Val missense_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620145 c.255T>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620157 c.267G>A synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620169 c.279G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620173 c.283_285delGTCinsCG frameshift_variant&missense_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620259 c.369C>T synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>A synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620313 c.423G>A synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsTG frameshift_variant&missense_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>T synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.91 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620454 c.564C>T synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620757 c.867C>T synonymous_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620763 c.873G>A synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620809 c.919C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620823 c.933C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620829 c.939G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620832 c.942C>T synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620847 c.957G>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620859 c.969G>C synonymous_variant 0.8 capreomycin
amikacin
kanamycin
Rv0565c 656031 c.1440A>G synonymous_variant 0.69 ethionamide
Rv0565c 656037 c.1434G>A synonymous_variant 0.77 ethionamide
Rv0565c 656043 c.1428C>G synonymous_variant 0.77 ethionamide
Rv0565c 656052 c.1419A>C synonymous_variant 0.71 ethionamide
Rv0565c 656064 c.1407C>A synonymous_variant 0.73 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 0.79 ethionamide Uncertain significance
Rv0565c 656076 c.1395C>T synonymous_variant 0.79 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 0.81 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.81 ethionamide
Rv0565c 656091 c.1380T>C synonymous_variant 0.83 ethionamide
Rv0565c 656112 c.1359C>G synonymous_variant 0.82 ethionamide
Rv0565c 656118 c.1353C>G synonymous_variant 0.79 ethionamide
Rv0565c 656430 c.1041C>G synonymous_variant 0.85 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 0.95 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.95 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.95 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 0.94 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.94 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.94 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.89 ethionamide
Rv0565c 656502 c.967_969delCACinsAA frameshift_variant&missense_variant 0.88 ethionamide Uncertain significance
Rv0565c 656511 p.His320Gln missense_variant 0.96 ethionamide
Rv0565c 656533 c.937_938delCGinsAGA frameshift_variant&missense_variant 0.91 ethionamide Uncertain significance
Rv0565c 656535 c.936C>G synonymous_variant 0.91 ethionamide
Rv0565c 656539 c.931delA frameshift_variant 1.0 ethionamide Uncertain significance
Rv0565c 656559 c.912C>T synonymous_variant 0.93 ethionamide
Rv0565c 656571 c.900C>T synonymous_variant 0.88 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 0.94 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 0.94 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 0.93 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 0.73 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 0.8 ethionamide
Rv0565c 657241 p.Glu77Arg missense_variant 0.8 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.83 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.83 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 0.83 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.69 ethionamide
Rv0565c 657608 c.-138C>G upstream_gene_variant 0.6 ethionamide
Rv0565c 657620 c.-150C>T upstream_gene_variant 0.55 ethionamide
Rv0565c 657626 c.-156C>T upstream_gene_variant 0.85 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.68 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.69 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.72 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.95 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.74 ethionamide
Rv0565c 657680 c.-210G>A upstream_gene_variant 0.73 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.92 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.93 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.88 ethionamide
hadA 731747 c.-183T>C upstream_gene_variant 0.97 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.98 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.84 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.98 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.85 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.85 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.82 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.92 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.86 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.95 isoniazid
hadA 731864 c.-66C>T upstream_gene_variant 0.86 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.86 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.81 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.87 isoniazid
hadA 732301 c.372G>A synonymous_variant 0.96 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.96 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.96 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.96 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.93 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.97 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.98 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.93 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.84 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.94 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.95 isoniazid
nusG 734078 c.-176C>A upstream_gene_variant 0.86 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 0.86 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.7 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.68 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.86 rifampicin Uncertain significance
nusG 734123 c.-131C>T upstream_gene_variant 0.66 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 0.87 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.67 rifampicin
nusG 734135 c.-119G>T upstream_gene_variant 0.67 rifampicin
nusG 734144 c.-110G>T upstream_gene_variant 0.61 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.83 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.63 rifampicin Uncertain significance
nusG 734205 c.-49A>C upstream_gene_variant 0.92 rifampicin
nusG 734222 c.-31_-27delGGCTC upstream_gene_variant 0.86 rifampicin
nusG 734229 c.-25A>C upstream_gene_variant 0.86 rifampicin
nusG 734247 c.-7_-6delGAinsC upstream_gene_variant 0.71 rifampicin
nusG 734275 p.Thr8Pro missense_variant 0.68 rifampicin
nusG 734289 p.Glu12Asp missense_variant 0.67 rifampicin
nusG 734348 p.Val32Ala missense_variant 0.7 rifampicin
nusG 734362 p.Ala37Thr missense_variant 0.61 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.89 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.73 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.73 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.9 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.75 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.8 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.8 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.82 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 0.99 rifampicin
nusG 734520 c.267C>G synonymous_variant 0.83 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.94 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.92 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 0.91 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.91 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.94 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.93 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.92 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.9 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.82 rifampicin
nusG 734658 c.405A>G synonymous_variant 0.83 rifampicin Not assoc w R
nusG 734664 c.411T>G synonymous_variant 0.9 rifampicin
nusG 734667 c.414C>T synonymous_variant 0.73 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.91 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsAG frameshift_variant&missense_variant 0.73 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.9 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.85 rifampicin
nusG 734750 p.Ser166Thr missense_variant 0.67 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.87 rifampicin
nusG 734757 c.504T>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734762 p.Ala170Val missense_variant 0.67 rifampicin
nusG 734766 c.513C>A synonymous_variant 0.67 rifampicin
nusG 734771 p.Ala173Val missense_variant 0.71 rifampicin
nusG 734778 c.525G>T synonymous_variant 0.85 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.87 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.87 rifampicin
nusG 734792 p.Val180Ala missense_variant 0.79 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.81 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.85 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.92 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.96 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.81 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.78 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.72 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.98 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.94 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.93 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.93 rifampicin
nusG 734931 c.678A>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734949 c.696T>C synonymous_variant 0.83 rifampicin
rpoB 759629 c.-178T>C upstream_gene_variant 1.0 rifampicin
rpoB 759636 c.-171C>T upstream_gene_variant 0.94 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.94 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.94 rifampicin Uncertain significance
rpoB 759655 c.-152_-151insCCTTA upstream_gene_variant 0.9 rifampicin
rpoB 759658 c.-148_-145delTTGC upstream_gene_variant 0.9 rifampicin
rpoB 759667 c.-140C>T upstream_gene_variant 0.9 rifampicin Uncertain significance
rpoB 759670 c.-137C>T upstream_gene_variant 0.9 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.9 rifampicin
rpoB 759672 c.-135G>C upstream_gene_variant 0.9 rifampicin
rpoB 759683 c.-124T>C upstream_gene_variant 0.9 rifampicin
rpoB 760060 p.Tyr85Leu missense_variant 0.69 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.73 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.72 rifampicin
rpoB 760088 c.282C>G synonymous_variant 0.71 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.92 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.84 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.92 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.91 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.97 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.93 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.9 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.95 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.95 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 0.86 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760451 c.645C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>G synonymous_variant 0.74 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.95 rifampicin
rpoB 760547 c.741G>T synonymous_variant 0.78 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.94 rifampicin Uncertain significance
rpoB 760589 c.783C>G synonymous_variant 0.78 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.93 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 0.96 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.91 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.9 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.86 rifampicin
rpoB 760784 c.978G>C synonymous_variant 0.86 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.87 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.91 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.93 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 0.92 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.96 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.98 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>T synonymous_variant 0.97 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.98 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.95 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.95 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.95 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 0.91 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.94 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.96 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.95 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>A synonymous_variant 0.9 rifampicin
rpoB 761207 c.1401C>G synonymous_variant 0.9 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.89 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761286 c.1480C>T synonymous_variant 0.72 rifampicin
rpoB 761289 p.Ser495Ala missense_variant 0.68 rifampicin
rpoB 761292 p.Val496Thr missense_variant 0.64 rifampicin
rpoB 761297 c.1491C>T synonymous_variant 0.71 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>A synonymous_variant 0.93 rifampicin
rpoB 761345 c.1539G>T synonymous_variant 0.81 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.9 rifampicin
rpoB 761358 c.1552_1554delGTTinsAC frameshift_variant&missense_variant 0.8 rifampicin
rpoB 761373 p.Val523His missense_variant 0.78 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.78 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.83 rifampicin
rpoB 761474 c.1668C>A synonymous_variant 0.56 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.86 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.92 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.78 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.82 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.98 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761651 c.1845C>T synonymous_variant 0.87 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>G synonymous_variant 0.97 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.97 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.79 rifampicin
rpoB 761693 c.1887G>T synonymous_variant 0.82 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.87 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.85 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.83 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.75 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.75 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.75 rifampicin
rpoB 761807 c.2001C>T synonymous_variant 0.75 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.75 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.69 rifampicin
rpoB 761867 c.2061C>G synonymous_variant 0.85 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.92 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.92 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.9 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.65 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.69 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.93 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.93 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.67 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.93 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.94 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762095 c.2289C>T synonymous_variant 0.91 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.96 rifampicin Uncertain significance
rpoB 762138 c.2332C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.94 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>G synonymous_variant 0.88 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>T synonymous_variant 0.88 rifampicin
rpoB 762233 c.2427G>T synonymous_variant 0.92 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>A synonymous_variant 0.93 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.92 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.98 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.98 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.94 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 0.98 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.98 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.98 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.98 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.96 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.94 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 0.94 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.81 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.94 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.94 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.94 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.93 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.88 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.88 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 0.92 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 0.57 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 0.54 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.65 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 0.74 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 0.94 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 0.93 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.85 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 0.89 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.96 rifampicin
rpoC 762818 c.-552C>A upstream_gene_variant 0.96 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.93 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.97 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.89 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.88 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.96 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.97 rifampicin
rpoC 763178 c.-192G>C upstream_gene_variant 0.9 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 0.89 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.93 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.88 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.95 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.94 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.76 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.71 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.88 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.97 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.97 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.98 rifampicin
rpoC 763495 c.126G>A synonymous_variant 0.9 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 0.98 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.84 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>A synonymous_variant 0.9 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.97 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.75 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.81 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.98 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.98 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.98 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763831 c.462A>G synonymous_variant 0.87 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.88 rifampicin
rpoC 763853 c.484_486delGTCinsAT frameshift_variant&missense_variant 0.91 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.95 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.98 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.97 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.98 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.97 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.86 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.97 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.97 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763972 c.603C>T synonymous_variant 0.68 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.65 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.65 rifampicin
rpoC 764002 c.633C>T synonymous_variant 0.68 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.92 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.9 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.75 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.79 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.95 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.98 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.98 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.86 rifampicin
rpoC 764110 c.741C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764159 c.790C>T synonymous_variant 0.98 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Thr missense_variant 0.89 rifampicin
rpoC 764198 c.829C>T synonymous_variant 0.89 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.95 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.96 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.96 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.81 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>T synonymous_variant 0.86 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.92 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.95 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.86 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.98 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.87 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.98 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.89 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.98 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.96 rifampicin
rpoC 764593 c.1224C>A synonymous_variant 0.88 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>A synonymous_variant 0.87 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.97 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.8 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764959 c.1590G>A synonymous_variant 0.71 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764971 c.1602C>T synonymous_variant 0.7 rifampicin
rpoC 764995 c.1626C>G synonymous_variant 0.83 rifampicin Not assoc w R
rpoC 765005 c.1637_1638insGC frameshift_variant 0.95 rifampicin
rpoC 765010 p.Leu547Phe missense_variant 0.8 rifampicin
rpoC 765011 p.Ser548Gly missense_variant 0.8 rifampicin
rpoC 765014 c.1646_1647delCC frameshift_variant 0.95 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>T synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.86 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.75 rifampicin Uncertain significance
rpoC 765310 c.1941G>A synonymous_variant 0.76 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.9 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.9 rifampicin Uncertain significance
rpoC 765352 c.1983G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765370 c.2001G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765371 c.2002C>T synonymous_variant 0.88 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.88 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.91 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>T synonymous_variant 0.87 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.96 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.98 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.98 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.91 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.89 rifampicin
rpoC 765583 c.2214G>C synonymous_variant 0.89 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.97 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.89 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.89 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.86 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.98 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.88 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.99 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.98 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.98 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.98 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.95 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.99 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.94 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.78 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.97 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.97 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.97 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.71 rifampicin
rpoC 766061 c.2692_2694delGTCinsCG frameshift_variant&missense_variant 0.72 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766087 c.2718C>G synonymous_variant 0.73 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766097 p.Leu910Val missense_variant 0.74 rifampicin
rpoC 766108 c.2739C>T synonymous_variant 0.75 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766147 c.2778C>T synonymous_variant 0.83 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.83 rifampicin Uncertain significance
rpoC 766288 c.2919C>T synonymous_variant 0.79 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 0.71 rifampicin
rpoC 766312 c.2943T>G synonymous_variant 0.94 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.96 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.97 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.97 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.97 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.85 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.96 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.96 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.89 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.95 rifampicin
rpoC 766435 c.3066G>A synonymous_variant 0.72 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.7 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 0.97 rifampicin
rpoC 766477 c.3108G>A synonymous_variant 0.76 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 0.74 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.95 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.74 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.97 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>T synonymous_variant 0.89 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.98 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.98 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.98 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.96 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.96 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.98 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.96 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.87 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.94 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.94 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.94 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766726 c.3357T>C synonymous_variant 0.97 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.98 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.97 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.96 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766813 c.3444G>C synonymous_variant 0.87 rifampicin
rpoC 766861 c.3492G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.98 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.98 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.98 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.89 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.99 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.98 rifampicin
rpoC 766978 c.3609C>A synonymous_variant 0.87 rifampicin
rpoC 766996 c.3627C>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.89 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.99 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.98 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>G synonymous_variant 1.0 rifampicin
rpoC 767212 c.3843G>C synonymous_variant 0.83 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.88 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.71 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.88 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
mmpL5 775718 c.2763C>G synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 775742 c.2739C>T synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 775745 c.2734_2736delATGinsCC frameshift_variant&missense_variant 0.55 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775904 c.2577G>A synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.76 clofazimine
bedaquiline
mmpL5 775912 c.2569C>A synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775922 c.2559G>C synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.9 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.97 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.98 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.97 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 0.96 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 776036 c.2445G>A synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 777143 c.1338G>A synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 777149 c.1332C>T synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.82 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 0.81 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 0.81 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 777212 c.1269C>G synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 777239 c.1242C>T synonymous_variant 0.73 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.8 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.89 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.86 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.93 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.89 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.95 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.93 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.94 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.94 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.83 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.95 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.82 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.93 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.88 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.96 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.94 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.91 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.91 streptomycin
rpsL 781772 c.213C>G synonymous_variant 0.93 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.98 streptomycin
rpsL 781814 c.255C>G synonymous_variant 0.93 streptomycin
rpsL 781817 c.258G>A synonymous_variant 0.98 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.98 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.98 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.92 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.97 streptomycin
rpsL 781853 c.294C>T synonymous_variant 0.94 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.91 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.83 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.96 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.91 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.91 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.95 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.95 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.95 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.95 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.77 linezolid
rplC 800594 c.-215C>T upstream_gene_variant 0.77 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.78 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.95 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.96 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.78 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.95 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.96 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.8 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.97 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.81 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.82 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.81 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.85 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>C upstream_gene_variant 1.0 linezolid
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 0.95 linezolid
rplC 800865 c.57A>G synonymous_variant 0.87 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.87 linezolid
rplC 800874 c.66A>G synonymous_variant 0.8 linezolid
rplC 800904 c.96G>C synonymous_variant 0.83 linezolid
rplC 800907 c.99C>G synonymous_variant 0.67 linezolid
rplC 800916 c.108A>G synonymous_variant 0.85 linezolid
rplC 800922 c.114C>G synonymous_variant 0.75 linezolid
rplC 800937 c.129A>G synonymous_variant 0.8 linezolid
rplC 800962 c.154C>T synonymous_variant 0.93 linezolid
rplC 800970 c.162T>C synonymous_variant 0.93 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.89 linezolid
rplC 800985 c.177A>C synonymous_variant 0.94 linezolid
rplC 801004 p.Leu66Val missense_variant 0.94 linezolid
rplC 801009 c.201A>C synonymous_variant 0.94 linezolid
rplC 801027 c.219C>G synonymous_variant 0.93 linezolid
rplC 801136 p.Ser110Gly missense_variant 0.86 linezolid
rplC 801147 c.339T>C synonymous_variant 0.9 linezolid
rplC 801150 c.342G>C synonymous_variant 0.87 linezolid
rplC 801153 c.345G>C synonymous_variant 0.87 linezolid
rplC 801156 c.348T>C synonymous_variant 0.9 linezolid
rplC 801171 c.363A>G synonymous_variant 0.92 linezolid
rplC 801174 c.366T>C synonymous_variant 0.93 linezolid
rplC 801195 c.387G>C synonymous_variant 0.9 linezolid
rplC 801246 c.438C>T synonymous_variant 0.95 linezolid
rplC 801249 c.441T>C synonymous_variant 0.95 linezolid
rplC 801255 c.447C>T synonymous_variant 0.95 linezolid
rplC 801267 c.459A>C synonymous_variant 0.91 linezolid
rplC 801270 c.462T>C synonymous_variant 0.9 linezolid
rplC 801276 c.468G>C synonymous_variant 0.88 linezolid
rplC 801279 c.471G>C synonymous_variant 0.88 linezolid
rplC 801282 c.474G>T synonymous_variant 0.88 linezolid
rplC 801309 c.501C>G synonymous_variant 0.88 linezolid
rplC 801312 c.504G>C synonymous_variant 0.87 linezolid
rplC 801321 c.513C>T synonymous_variant 0.85 linezolid Not assoc w R - Interim
rplC 801323 p.Asn172Ser missense_variant 0.85 linezolid
rplC 801327 c.519C>T synonymous_variant 0.86 linezolid
rplC 801339 c.531T>C synonymous_variant 0.96 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.96 linezolid
rplC 801348 c.540T>G synonymous_variant 0.96 linezolid
rplC 801357 c.549T>C synonymous_variant 0.97 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801420 c.612A>G synonymous_variant 0.92 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801427 p.Met207Val missense_variant 0.95 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
rplC 801442 p.Ile212Val missense_variant 0.95 linezolid
fbiC 1303441 c.511T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 0.81 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303479 c.549G>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>A synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303647 c.717G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303716 c.786C>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303785 c.855G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303812 c.882C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303821 c.891C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303902 c.972G>A synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303923 c.993C>T synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303929 c.999G>A synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303932 c.1002G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304530 p.Ser534Thr missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304544 p.Asp538Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304550 c.1620C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.82 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.81 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304778 c.1848T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304796 c.1866G>A synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304904 c.1974G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>T synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304988 c.2058G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305114 c.2184T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305279 p.His783Gln missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305348 c.2418C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305349 c.2419C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305430 p.Val834Ile missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305444 p.Glu838Asp missense_variant 0.89 clofazimine
pretomanid
delamanid
sigE 1364862 c.450C>G synonymous_variant 0.79 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.79 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.92 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.5 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.67 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.82 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.86 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.91 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.92 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.93 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 0.92 pyrazinamide
sigE 1365075 c.663G>A synonymous_variant 0.92 pyrazinamide
sigE 1365081 c.669G>C synonymous_variant 0.96 pyrazinamide
sigE 1365084 c.672G>T synonymous_variant 0.96 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 1.0 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 1.0 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 1.0 pyrazinamide
sigE 1365111 c.699C>T synonymous_variant 1.0 pyrazinamide
sigE 1365117 c.705A>G synonymous_variant 0.91 pyrazinamide
atpE 1460816 c.-229T>C upstream_gene_variant 0.91 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.98 bedaquiline
atpE 1460840 c.-205A>C upstream_gene_variant 0.98 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.96 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.95 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.95 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.86 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.9 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 0.89 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.89 bedaquiline
atpE 1460915 c.-130C>G upstream_gene_variant 0.85 bedaquiline
atpE 1460918 c.-127A>C upstream_gene_variant 0.82 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.92 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.96 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 0.96 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.97 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.9 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461194 c.150C>T synonymous_variant 0.87 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.79 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
atpE 1461269 c.225C>G synonymous_variant 0.72 bedaquiline
atpE 1461275 c.231T>C synonymous_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1473981 n.324_325insT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474036 n.379G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474104 n.447G>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474110 n.453A>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475201 n.1544G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673490 c.-712A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673499 c.-703T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673502 c.-700C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673505 c.-697A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673535 c.-667A>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673541 c.-661G>A upstream_gene_variant 0.88 ethionamide
isoniazid Uncertain significance
inhA 1673547 c.-655T>C upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.73 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673592 c.-610G>A upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.71 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.8 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 0.8 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.88 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 0.81 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.93 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.93 ethionamide
isoniazid
inhA 1673664 c.-538A>T upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673682 c.-520G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1673710 p.Leu91Ile missense_variant 1.0 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673763 c.-439C>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673890 p.Ala151Ser missense_variant 0.75 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673916 c.-286A>G upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673917 c.478_480delGTGinsCC frameshift_variant&missense_variant 0.85 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1673934 c.-268C>T upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.87 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.87 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.86 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.82 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 0.81 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 0.87 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.73 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.77 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 0.83 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGG frameshift_variant&missense_variant 0.79 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 0.73 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.92 ethionamide
isoniazid
inhA 1674084 c.-118C>G upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.91 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1674144 c.-58G>T upstream_gene_variant 0.78 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1674321 c.120G>A synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674331 c.130C>T synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674336 c.135G>C synonymous_variant 0.68 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 0.77 ethionamide Uncertain significance
isoniazid
inhA 1674368 p.Ala56Glu missense_variant 0.81 ethionamide
isoniazid
inhA 1674375 c.174C>G synonymous_variant 0.73 ethionamide
isoniazid
inhA 1674382 p.Leu61Ile missense_variant 0.86 ethionamide
isoniazid
inhA 1674471 c.270G>T synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674501 c.300G>A synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.94 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.88 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.97 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.86 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674636 c.435C>G synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674669 c.468G>T synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674672 c.471C>T synonymous_variant 0.83 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674690 c.489C>G synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCA frameshift_variant&missense_variant 0.72 ethionamide
isoniazid
inhA 1674729 c.528G>A synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674738 c.537C>G synonymous_variant 0.76 ethionamide
isoniazid