TB-Profiler result

Run: ERR176568
Summary

Run ID: ERR176568

Sample name:

Date: 2024-04-15T23:34:19.793313

Number of reads: 780263

Percentage reads mapped: 16.86

Median coverage: 13.0

Strain: La3;lineage2.1;lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.2.2 West-Africa 2 RD702 0.07
La1.2.BCG M.bovis None 0.18
lineage2.1 East-Asian (non-Beijing) None 0.07
lineage6.2.3 West-Africa 2 RD702 0.06
lineage4.9 Euro-American (H37Rv-like) None 0.83
La3 M.orygis None 0.09
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2269_2271delGCGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 0.73 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305199 c.2269_2271delGCGinsTC frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance Mutation from literature
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.91 isoniazid Assoc w R High-level resistance
embB 4247448 p.His312Arg missense_variant 0.85 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 549 c.549C>T synonymous_variant 0.57 isoniazid
dnaA 558 c.558G>C synonymous_variant 0.71 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.76 isoniazid
dnaA 597 c.597C>G synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>G synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.81 isoniazid
dnaA 645 c.645A>T synonymous_variant 0.93 isoniazid
dnaA 652 c.652_654delCTAinsTG frameshift_variant&stop_gained 0.9 isoniazid Uncertain significance
dnaA 660 c.660G>C synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.84 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.82 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>A synonymous_variant 0.82 isoniazid
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 0.82 isoniazid Uncertain significance
dnaA 693 c.693A>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 708 c.708T>C synonymous_variant 0.88 isoniazid
dnaA 711 c.711C>G synonymous_variant 0.88 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>T synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 0.92 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.94 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.93 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.9 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.93 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.92 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.86 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.89 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.91 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.91 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.92 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.92 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.89 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.92 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.84 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.92 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.91 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.91 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.96 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.94 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.72 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.71 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.95 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>A synonymous_variant 0.75 isoniazid
dnaA 1029 c.1029C>A synonymous_variant 0.67 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.73 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.8 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1062 c.1062C>A synonymous_variant 0.86 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 1.0 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.8 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.92 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.92 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 0.62 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.86 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.88 isoniazid
dnaA 1146 c.1146C>T synonymous_variant 0.29 isoniazid
dnaA 1149 c.1149C>T synonymous_variant 0.62 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.9 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 0.86 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.6 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.9 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.55 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.64 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 1203 c.1203T>C synonymous_variant 0.3 isoniazid
dnaA 1204 c.1204C>T synonymous_variant 0.67 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.97 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.98 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.95 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.84 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>G synonymous_variant 0.82 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.93 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.84 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.91 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.91 isoniazid
dnaA 1317 c.1317A>C synonymous_variant 0.85 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.65 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>C synonymous_variant 0.8 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 0.53 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.8 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.76 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.69 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.76 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.55 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.8 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.81 isoniazid
dnaA 1413 c.1413A>G synonymous_variant 0.77 isoniazid Not assoc w R - Interim
dnaA 1416 c.1416C>G synonymous_variant 0.84 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.72 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.72 isoniazid
dnaA 1440 c.1440C>T synonymous_variant 0.72 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.88 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.86 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.88 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.8 isoniazid
dnaA 1506 c.1506T>C synonymous_variant 0.75 isoniazid
gyrB 6115 c.876A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.73 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.7 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6262 c.1023G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6355 c.-947G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6397 c.1158G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6403 c.-899T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6412 c.-890G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6457 c.-845T>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6664 c.1425C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6673 c.-629A>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6688 c.-614C>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.73 levofloxacin Uncertain significance
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.96 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 6803 c.-499C>T upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6889 c.-413G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6961 c.-341G>A upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6991 c.-311C>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 7162 c.1923C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7178 c.-124T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7237 c.-65C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7347 p.Glu16Gln missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7445 c.144C>T synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7451 c.150C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7508 c.207C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7577 c.276C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7592 c.291G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7853 c.552C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7871 c.570G>A synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8054 c.753T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8228 c.927G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8337 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.77 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.77 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8369 c.1068G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8492 c.1191G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8537 p.Glu412Asp missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8570 c.1269G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Arg missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8963 c.1662C>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9080 c.1779G>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9110 c.1809G>A synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9122 c.1821C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9134 c.1833C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.91 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9182 c.1881T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9203 c.1902G>A synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9318 c.2017C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9329 c.2028C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9572 c.2271C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9578 c.2277C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.89 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.8 isoniazid
fgd1 490797 c.15G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490858 p.Ala26Thr missense_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490984 c.202C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>T synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491052 c.270C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491070 c.288G>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491083 p.Val101Ile missense_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491088 c.306C>T synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491110 p.Ala110Ser missense_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491124 c.342C>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491160 c.378G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491631 c.849C>T synonymous_variant 0.7 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491646 c.864G>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
mshA 574616 c.-732G>T upstream_gene_variant 0.7 ethionamide
isoniazid
mshA 574619 c.-729C>G upstream_gene_variant 0.69 ethionamide
isoniazid
mshA 574640 c.-708G>C upstream_gene_variant 0.85 ethionamide
isoniazid
mshA 574646 c.-702G>A upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 574655 c.-693C>G upstream_gene_variant 0.84 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 574671 c.-677_-675delGCAinsCTG upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.9 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.9 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574715 c.-633C>G upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 0.91 ethionamide
isoniazid
mshA 575515 c.168G>A synonymous_variant 0.73 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.77 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.86 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575542 c.195C>G synonymous_variant 0.65 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.89 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.63 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.89 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.63 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575587 c.240C>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575618 c.271C>A synonymous_variant 0.59 ethionamide
isoniazid
mshA 575623 c.276C>G synonymous_variant 0.5 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.75 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 0.7 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.7 ethionamide
isoniazid
mshA 575649 p.Val101Glu missense_variant 0.7 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575692 c.345G>C synonymous_variant 0.76 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.92 ethionamide
isoniazid Not assoc w R - Interim
mshA 575705 c.358T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.97 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.86 ethionamide
isoniazid
mshA 575764 c.417C>T synonymous_variant 0.82 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.96 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.86 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.87 ethionamide
isoniazid
mshA 575818 c.471G>T synonymous_variant 0.84 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575824 c.477T>A synonymous_variant 0.85 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.74 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575878 c.531A>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 576193 c.846T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576197 c.850C>T synonymous_variant 0.88 ethionamide
isoniazid
mshA 576202 c.855T>C synonymous_variant 0.88 ethionamide
isoniazid Not assoc w R - Interim
mshA 576211 c.864C>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 576215 c.868T>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 576233 c.886_888delATCinsGG frameshift_variant&missense_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576247 c.900A>G synonymous_variant 0.91 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619528 c.-363C>A upstream_gene_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 619530 c.-360_-358delTCA upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619537 c.-354_-353insTCG upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619618 c.-273C>G upstream_gene_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>G upstream_gene_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>G upstream_gene_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620121 c.231G>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620126 p.Gly79Ala missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620139 c.249C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620141 p.Ala84Val missense_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620145 c.255T>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620157 c.267G>A synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620169 c.279G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620173 c.283_285delGTCinsCG frameshift_variant&missense_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620259 c.369C>T synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>A synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620313 c.423G>A synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsTG frameshift_variant&missense_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>T synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.91 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620454 c.564C>T synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620757 c.867C>T synonymous_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620763 c.873G>A synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620809 c.919C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620823 c.933C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620829 c.939G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620832 c.942C>T synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620847 c.957G>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620859 c.969G>C synonymous_variant 0.8 capreomycin
amikacin
kanamycin
Rv0565c 656031 c.1440A>G synonymous_variant 0.69 ethionamide
Rv0565c 656037 c.1434G>A synonymous_variant 0.77 ethionamide
Rv0565c 656043 c.1428C>G synonymous_variant 0.77 ethionamide
Rv0565c 656052 c.1419A>C synonymous_variant 0.71 ethionamide
Rv0565c 656064 c.1407C>A synonymous_variant 0.73 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 0.79 ethionamide Uncertain significance
Rv0565c 656076 c.1395C>T synonymous_variant 0.79 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 0.81 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.81 ethionamide
Rv0565c 656091 c.1380T>C synonymous_variant 0.83 ethionamide
Rv0565c 656112 c.1359C>G synonymous_variant 0.82 ethionamide
Rv0565c 656118 c.1353C>G synonymous_variant 0.79 ethionamide
Rv0565c 656430 c.1041C>G synonymous_variant 0.85 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 0.95 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.95 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.95 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 0.94 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.94 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.94 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.89 ethionamide
Rv0565c 656502 c.967_969delCACinsAA frameshift_variant&missense_variant 0.88 ethionamide Uncertain significance
Rv0565c 656511 p.His320Gln missense_variant 0.96 ethionamide
Rv0565c 656533 c.937_938delCGinsAGA frameshift_variant&missense_variant 0.91 ethionamide Uncertain significance
Rv0565c 656535 c.936C>G synonymous_variant 0.91 ethionamide
Rv0565c 656539 c.931delA frameshift_variant 1.0 ethionamide Uncertain significance
Rv0565c 656559 c.912C>T synonymous_variant 0.93 ethionamide
Rv0565c 656571 c.900C>T synonymous_variant 0.88 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 0.94 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 0.94 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 0.93 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 0.73 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 0.8 ethionamide
Rv0565c 657241 p.Glu77Arg missense_variant 0.8 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.83 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.83 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 0.83 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.69 ethionamide
Rv0565c 657608 c.-138C>G upstream_gene_variant 0.6 ethionamide
Rv0565c 657620 c.-150C>T upstream_gene_variant 0.55 ethionamide
Rv0565c 657626 c.-156C>T upstream_gene_variant 0.85 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.68 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.69 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.72 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.95 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.74 ethionamide
Rv0565c 657680 c.-210G>A upstream_gene_variant 0.73 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.92 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.93 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.88 ethionamide
hadA 731747 c.-183T>C upstream_gene_variant 0.97 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.98 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.84 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.98 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.85 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.85 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.82 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.92 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.86 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.95 isoniazid
hadA 731864 c.-66C>T upstream_gene_variant 0.86 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.86 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.81 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.87 isoniazid
hadA 732301 c.372G>A synonymous_variant 0.96 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.96 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.96 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.96 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.93 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.97 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.98 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.93 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.84 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.94 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.95 isoniazid
nusG 734078 c.-176C>A upstream_gene_variant 0.86 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 0.86 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.7 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.68 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.86 rifampicin Uncertain significance
nusG 734123 c.-131C>T upstream_gene_variant 0.66 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 0.87 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.67 rifampicin
nusG 734135 c.-119G>T upstream_gene_variant 0.67 rifampicin
nusG 734144 c.-110G>T upstream_gene_variant 0.61 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.83 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.63 rifampicin Uncertain significance
nusG 734205 c.-49A>C upstream_gene_variant 0.92 rifampicin
nusG 734222 c.-31_-27delGGCTC upstream_gene_variant 0.86 rifampicin
nusG 734229 c.-25A>C upstream_gene_variant 0.86 rifampicin
nusG 734247 c.-7_-6delGAinsC upstream_gene_variant 0.71 rifampicin
nusG 734275 p.Thr8Pro missense_variant 0.68 rifampicin
nusG 734289 p.Glu12Asp missense_variant 0.67 rifampicin
nusG 734348 p.Val32Ala missense_variant 0.7 rifampicin
nusG 734362 p.Ala37Thr missense_variant 0.61 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.89 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.73 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.73 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.9 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.75 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.8 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.8 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.82 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 0.99 rifampicin
nusG 734520 c.267C>G synonymous_variant 0.83 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.94 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.92 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 0.91 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.91 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.94 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.93 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.92 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.9 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.82 rifampicin
nusG 734658 c.405A>G synonymous_variant 0.83 rifampicin Not assoc w R
nusG 734664 c.411T>G synonymous_variant 0.9 rifampicin
nusG 734667 c.414C>T synonymous_variant 0.73 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.91 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsAG frameshift_variant&missense_variant 0.73 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.9 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.85 rifampicin
nusG 734750 p.Ser166Thr missense_variant 0.67 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.87 rifampicin
nusG 734757 c.504T>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734762 p.Ala170Val missense_variant 0.67 rifampicin
nusG 734766 c.513C>A synonymous_variant 0.67 rifampicin
nusG 734771 p.Ala173Val missense_variant 0.71 rifampicin
nusG 734778 c.525G>T synonymous_variant 0.85 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.87 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.87 rifampicin
nusG 734792 p.Val180Ala missense_variant 0.79 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.81 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.85 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.92 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.96 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.81 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.78 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.72 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.98 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.94 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.93 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.93 rifampicin
nusG 734931 c.678A>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734949 c.696T>C synonymous_variant 0.83 rifampicin
rpoB 759629 c.-178T>C upstream_gene_variant 1.0 rifampicin
rpoB 759636 c.-171C>T upstream_gene_variant 0.94 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.94 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.94 rifampicin Uncertain significance
rpoB 759655 c.-152_-151insCCTTA upstream_gene_variant 0.9 rifampicin
rpoB 759658 c.-148_-145delTTGC upstream_gene_variant 0.9 rifampicin
rpoB 759667 c.-140C>T upstream_gene_variant 0.9 rifampicin Uncertain significance
rpoB 759670 c.-137C>T upstream_gene_variant 0.9 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.9 rifampicin
rpoB 759672 c.-135G>C upstream_gene_variant 0.9 rifampicin
rpoB 759683 c.-124T>C upstream_gene_variant 0.9 rifampicin
rpoB 760060 p.Tyr85Leu missense_variant 0.69 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.73 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.72 rifampicin
rpoB 760088 c.282C>G synonymous_variant 0.71 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.92 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.84 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.92 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.91 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.97 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.93 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.9 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.95 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.95 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 0.86 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760451 c.645C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>G synonymous_variant 0.74 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.95 rifampicin
rpoB 760547 c.741G>T synonymous_variant 0.78 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.94 rifampicin Uncertain significance
rpoB 760589 c.783C>G synonymous_variant 0.78 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.93 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 0.96 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.91 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.9 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.86 rifampicin
rpoB 760784 c.978G>C synonymous_variant 0.86 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.87 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.91 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.93 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 0.92 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.96 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.98 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>T synonymous_variant 0.97 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.98 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.95 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.95 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.95 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 0.91 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.94 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.96 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.95 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>A synonymous_variant 0.9 rifampicin
rpoB 761207 c.1401C>G synonymous_variant 0.9 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.89 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761286 c.1480C>T synonymous_variant 0.72 rifampicin
rpoB 761289 p.Ser495Ala missense_variant 0.68 rifampicin
rpoB 761292 p.Val496Thr missense_variant 0.64 rifampicin
rpoB 761297 c.1491C>T synonymous_variant 0.71 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>A synonymous_variant 0.93 rifampicin
rpoB 761345 c.1539G>T synonymous_variant 0.81 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.9 rifampicin
rpoB 761358 c.1552_1554delGTTinsAC frameshift_variant&missense_variant 0.8 rifampicin
rpoB 761373 p.Val523His missense_variant 0.78 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.78 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.83 rifampicin
rpoB 761474 c.1668C>A synonymous_variant 0.56 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.86 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.92 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.78 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.82 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.98 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761651 c.1845C>T synonymous_variant 0.87 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>G synonymous_variant 0.97 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.97 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.79 rifampicin
rpoB 761693 c.1887G>T synonymous_variant 0.82 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.87 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.85 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.83 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.75 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.75 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.75 rifampicin
rpoB 761807 c.2001C>T synonymous_variant 0.75 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.75 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.69 rifampicin
rpoB 761867 c.2061C>G synonymous_variant 0.85 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.92 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.92 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.9 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.65 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.69 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.93 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.93 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.67 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.93 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.94 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762095 c.2289C>T synonymous_variant 0.91 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.96 rifampicin Uncertain significance
rpoB 762138 c.2332C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.94 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>G synonymous_variant 0.88 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>T synonymous_variant 0.88 rifampicin
rpoB 762233 c.2427G>T synonymous_variant 0.92 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>A synonymous_variant 0.93 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.92 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.98 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.98 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.94 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 0.98 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.98 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.98 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.98 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.96 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.94 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 0.94 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.81 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.94 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.94 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.94 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.93 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.88 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.88 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 0.92 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 0.57 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 0.54 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.65 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 0.74 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 0.94 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 0.93 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.85 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 0.89 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.96 rifampicin
rpoC 762818 c.-552C>A upstream_gene_variant 0.96 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.93 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.97 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.89 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.88 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.96 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.97 rifampicin
rpoC 763178 c.-192G>C upstream_gene_variant 0.9 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 0.89 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.93 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.88 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.95 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.94 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.76 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.71 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.88 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.97 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.97 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.98 rifampicin
rpoC 763495 c.126G>A synonymous_variant 0.9 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 0.98 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.84 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>A synonymous_variant 0.9 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.97 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.75 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.81 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.98 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.98 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.98 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763831 c.462A>G synonymous_variant 0.87 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.88 rifampicin
rpoC 763853 c.484_486delGTCinsAT frameshift_variant&missense_variant 0.91 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.95 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.98 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.97 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.98 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.97 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.86 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.97 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.97 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763972 c.603C>T synonymous_variant 0.68 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.65 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.65 rifampicin
rpoC 764002 c.633C>T synonymous_variant 0.68 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.92 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.9 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.75 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.79 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.95 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.98 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.98 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.86 rifampicin
rpoC 764110 c.741C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764159 c.790C>T synonymous_variant 0.98 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Thr missense_variant 0.89 rifampicin
rpoC 764198 c.829C>T synonymous_variant 0.89 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.95 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.96 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.96 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.81 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>T synonymous_variant 0.86 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.92 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.95 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.86 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.98 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.87 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.98 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.89 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.98 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.96 rifampicin
rpoC 764593 c.1224C>A synonymous_variant 0.88 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>A synonymous_variant 0.87 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.97 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.8 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764959 c.1590G>A synonymous_variant 0.71 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764971 c.1602C>T synonymous_variant 0.7 rifampicin
rpoC 764995 c.1626C>G synonymous_variant 0.83 rifampicin Not assoc w R
rpoC 765005 c.1637_1638insGC frameshift_variant 0.95 rifampicin
rpoC 765010 p.Leu547Phe missense_variant 0.8 rifampicin
rpoC 765011 p.Ser548Gly missense_variant 0.8 rifampicin
rpoC 765014 c.1646_1647delCC frameshift_variant 0.95 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>T synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.86 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.75 rifampicin Uncertain significance
rpoC 765310 c.1941G>A synonymous_variant 0.76 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.9 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.9 rifampicin Uncertain significance
rpoC 765352 c.1983G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765370 c.2001G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765371 c.2002C>T synonymous_variant 0.88 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.88 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.91 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>T synonymous_variant 0.87 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.96 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.98 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.98 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.91 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.89 rifampicin
rpoC 765583 c.2214G>C synonymous_variant 0.89 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.97 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.89 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.89 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.86 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.98 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.88 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.99 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.98 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.98 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.98 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.95 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.99 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.94 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.78 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.97 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.97 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.97 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.71 rifampicin
rpoC 766061 c.2692_2694delGTCinsCG frameshift_variant&missense_variant 0.72 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766087 c.2718C>G synonymous_variant 0.73 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766097 p.Leu910Val missense_variant 0.74 rifampicin
rpoC 766108 c.2739C>T synonymous_variant 0.75 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766147 c.2778C>T synonymous_variant 0.83 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.83 rifampicin Uncertain significance
rpoC 766288 c.2919C>T synonymous_variant 0.79 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 0.71 rifampicin
rpoC 766312 c.2943T>G synonymous_variant 0.94 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.96 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.97 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.97 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.97 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.85 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.96 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.96 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.89 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.95 rifampicin
rpoC 766435 c.3066G>A synonymous_variant 0.72 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.7 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 0.97 rifampicin
rpoC 766477 c.3108G>A synonymous_variant 0.76 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 0.74 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.95 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.74 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.97 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>T synonymous_variant 0.89 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.98 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.98 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.98 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.96 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.96 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.98 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.96 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.87 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.94 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.94 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.94 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766726 c.3357T>C synonymous_variant 0.97 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.98 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.97 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.96 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766813 c.3444G>C synonymous_variant 0.87 rifampicin
rpoC 766861 c.3492G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.98 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.98 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.98 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.89 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.99 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.98 rifampicin
rpoC 766978 c.3609C>A synonymous_variant 0.87 rifampicin
rpoC 766996 c.3627C>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.89 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.99 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.98 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>G synonymous_variant 1.0 rifampicin
rpoC 767212 c.3843G>C synonymous_variant 0.83 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.88 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.71 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.88 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
mmpL5 775718 c.2763C>G synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 775742 c.2739C>T synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 775745 c.2734_2736delATGinsCC frameshift_variant&missense_variant 0.55 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775904 c.2577G>A synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.76 clofazimine
bedaquiline
mmpL5 775912 c.2569C>A synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775922 c.2559G>C synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.9 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.97 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.98 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.97 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 0.96 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 776036 c.2445G>A synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 777143 c.1338G>A synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 777149 c.1332C>T synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.82 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 0.81 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 0.81 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 777212 c.1269C>G synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 777239 c.1242C>T synonymous_variant 0.73 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.8 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.89 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.86 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.93 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.89 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.95 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.93 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.94 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.94 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.83 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.95 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.82 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.93 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.88 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.96 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.94 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.91 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.91 streptomycin
rpsL 781772 c.213C>G synonymous_variant 0.93 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.98 streptomycin
rpsL 781814 c.255C>G synonymous_variant 0.93 streptomycin
rpsL 781817 c.258G>A synonymous_variant 0.98 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.98 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.98 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.92 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.97 streptomycin
rpsL 781853 c.294C>T synonymous_variant 0.94 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.91 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.83 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.96 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.91 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.91 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.95 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.95 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.95 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.95 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.77 linezolid
rplC 800594 c.-215C>T upstream_gene_variant 0.77 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.78 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.95 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.96 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.78 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.95 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.96 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.8 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.97 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.81 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.82 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.81 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.85 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>C upstream_gene_variant 1.0 linezolid
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 0.95 linezolid
rplC 800865 c.57A>G synonymous_variant 0.87 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.87 linezolid
rplC 800874 c.66A>G synonymous_variant 0.8 linezolid
rplC 800904 c.96G>C synonymous_variant 0.83 linezolid
rplC 800907 c.99C>G synonymous_variant 0.67 linezolid
rplC 800916 c.108A>G synonymous_variant 0.85 linezolid
rplC 800922 c.114C>G synonymous_variant 0.75 linezolid
rplC 800937 c.129A>G synonymous_variant 0.8 linezolid
rplC 800962 c.154C>T synonymous_variant 0.93 linezolid
rplC 800970 c.162T>C synonymous_variant 0.93 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.89 linezolid
rplC 800985 c.177A>C synonymous_variant 0.94 linezolid
rplC 801004 p.Leu66Val missense_variant 0.94 linezolid
rplC 801009 c.201A>C synonymous_variant 0.94 linezolid
rplC 801027 c.219C>G synonymous_variant 0.93 linezolid
rplC 801136 p.Ser110Gly missense_variant 0.86 linezolid
rplC 801147 c.339T>C synonymous_variant 0.9 linezolid
rplC 801150 c.342G>C synonymous_variant 0.87 linezolid
rplC 801153 c.345G>C synonymous_variant 0.87 linezolid
rplC 801156 c.348T>C synonymous_variant 0.9 linezolid
rplC 801171 c.363A>G synonymous_variant 0.92 linezolid
rplC 801174 c.366T>C synonymous_variant 0.93 linezolid
rplC 801195 c.387G>C synonymous_variant 0.9 linezolid
rplC 801246 c.438C>T synonymous_variant 0.95 linezolid
rplC 801249 c.441T>C synonymous_variant 0.95 linezolid
rplC 801255 c.447C>T synonymous_variant 0.95 linezolid
rplC 801267 c.459A>C synonymous_variant 0.91 linezolid
rplC 801270 c.462T>C synonymous_variant 0.9 linezolid
rplC 801276 c.468G>C synonymous_variant 0.88 linezolid
rplC 801279 c.471G>C synonymous_variant 0.88 linezolid
rplC 801282 c.474G>T synonymous_variant 0.88 linezolid
rplC 801309 c.501C>G synonymous_variant 0.88 linezolid
rplC 801312 c.504G>C synonymous_variant 0.87 linezolid
rplC 801321 c.513C>T synonymous_variant 0.85 linezolid Not assoc w R - Interim
rplC 801323 p.Asn172Ser missense_variant 0.85 linezolid
rplC 801327 c.519C>T synonymous_variant 0.86 linezolid
rplC 801339 c.531T>C synonymous_variant 0.96 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.96 linezolid
rplC 801348 c.540T>G synonymous_variant 0.96 linezolid
rplC 801357 c.549T>C synonymous_variant 0.97 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801420 c.612A>G synonymous_variant 0.92 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801427 p.Met207Val missense_variant 0.95 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
rplC 801442 p.Ile212Val missense_variant 0.95 linezolid
fbiC 1303441 c.511T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 0.81 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303479 c.549G>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>A synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303647 c.717G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303716 c.786C>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303785 c.855G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303812 c.882C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303821 c.891C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303902 c.972G>A synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303923 c.993C>T synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303929 c.999G>A synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303932 c.1002G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304530 p.Ser534Thr missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304544 p.Asp538Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304550 c.1620C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.82 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.81 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304778 c.1848T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304796 c.1866G>A synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304904 c.1974G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>T synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304988 c.2058G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305114 c.2184T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305279 p.His783Gln missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305348 c.2418C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305349 c.2419C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305430 p.Val834Ile missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305444 p.Glu838Asp missense_variant 0.89 clofazimine
pretomanid
delamanid
sigE 1364862 c.450C>G synonymous_variant 0.79 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.79 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.92 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.5 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.67 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.82 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.86 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.91 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.92 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.93 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 0.92 pyrazinamide
sigE 1365075 c.663G>A synonymous_variant 0.92 pyrazinamide
sigE 1365081 c.669G>C synonymous_variant 0.96 pyrazinamide
sigE 1365084 c.672G>T synonymous_variant 0.96 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 1.0 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 1.0 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 1.0 pyrazinamide
sigE 1365111 c.699C>T synonymous_variant 1.0 pyrazinamide
sigE 1365117 c.705A>G synonymous_variant 0.91 pyrazinamide
atpE 1460816 c.-229T>C upstream_gene_variant 0.91 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.98 bedaquiline
atpE 1460840 c.-205A>C upstream_gene_variant 0.98 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.96 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.95 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.95 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.86 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.9 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 0.89 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.89 bedaquiline
atpE 1460915 c.-130C>G upstream_gene_variant 0.85 bedaquiline
atpE 1460918 c.-127A>C upstream_gene_variant 0.82 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.92 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.96 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 0.96 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.97 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.9 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461194 c.150C>T synonymous_variant 0.87 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.79 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
atpE 1461269 c.225C>G synonymous_variant 0.72 bedaquiline
atpE 1461275 c.231T>C synonymous_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1473981 n.324_325insT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474036 n.379G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474104 n.447G>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474110 n.453A>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475201 n.1544G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673490 c.-712A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673499 c.-703T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673502 c.-700C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673505 c.-697A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673535 c.-667A>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673541 c.-661G>A upstream_gene_variant 0.88 ethionamide
isoniazid Uncertain significance
inhA 1673547 c.-655T>C upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.73 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673592 c.-610G>A upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.71 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.8 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 0.8 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.88 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 0.81 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.93 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.93 ethionamide
isoniazid
inhA 1673664 c.-538A>T upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673682 c.-520G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1673710 p.Leu91Ile missense_variant 1.0 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673763 c.-439C>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673890 p.Ala151Ser missense_variant 0.75 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673916 c.-286A>G upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673917 c.478_480delGTGinsCC frameshift_variant&missense_variant 0.85 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1673934 c.-268C>T upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.87 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.87 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.86 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.82 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 0.81 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 0.87 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.73 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.77 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 0.83 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGG frameshift_variant&missense_variant 0.79 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 0.73 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.92 ethionamide
isoniazid
inhA 1674084 c.-118C>G upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.91 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1674144 c.-58G>T upstream_gene_variant 0.78 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1674321 c.120G>A synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674331 c.130C>T synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674336 c.135G>C synonymous_variant 0.68 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 0.77 ethionamide Uncertain significance
isoniazid
inhA 1674368 p.Ala56Glu missense_variant 0.81 ethionamide
isoniazid
inhA 1674375 c.174C>G synonymous_variant 0.73 ethionamide
isoniazid
inhA 1674382 p.Leu61Ile missense_variant 0.86 ethionamide
isoniazid
inhA 1674471 c.270G>T synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674501 c.300G>A synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.94 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.88 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.97 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.86 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674636 c.435C>G synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674669 c.468G>T synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674672 c.471C>T synonymous_variant 0.83 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674690 c.489C>G synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCA frameshift_variant&missense_variant 0.72 ethionamide
isoniazid
inhA 1674729 c.528G>A synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674738 c.537C>G synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674746 p.Tyr182Phe missense_variant 0.94 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.92 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674795 c.594G>C synonymous_variant 0.75 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674813 c.612C>T synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674840 c.639C>G synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.91 ethionamide
isoniazid
inhA 1674849 c.648G>A synonymous_variant 0.82 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674858 c.657G>A synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674873 c.672G>A synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.94 ethionamide
isoniazid
inhA 1674934 c.733C>T synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674939 c.738G>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674966 c.765T>G synonymous_variant 0.8 ethionamide
isoniazid
rpsA 1833471 c.-71A>G upstream_gene_variant 0.83 pyrazinamide
rpsA 1833474 c.-68_-67insA upstream_gene_variant 0.83 pyrazinamide
rpsA 1833489 c.-53T>A upstream_gene_variant 0.88 pyrazinamide
rpsA 1833495 c.-46_-45delCC upstream_gene_variant 0.78 pyrazinamide
rpsA 1833501 c.-41_-40insCAGAAT upstream_gene_variant 0.78 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 0.89 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.95 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 0.95 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.98 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
rpsA 1833721 c.180A>G synonymous_variant 0.86 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1833772 c.231C>T synonymous_variant 0.81 pyrazinamide
rpsA 1833782 p.Ser81Thr missense_variant 0.83 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.86 pyrazinamide
rpsA 1833844 c.303C>T synonymous_variant 0.87 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.99 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.99 pyrazinamide
rpsA 1833901 c.360G>A synonymous_variant 0.92 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.88 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.91 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.92 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834165 c.624A>G synonymous_variant 0.8 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.8 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834192 c.651C>T synonymous_variant 0.69 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.73 pyrazinamide
rpsA 1834213 c.672G>A synonymous_variant 0.75 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 0.88 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 0.87 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.85 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 0.9 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.88 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.85 pyrazinamide
rpsA 1834477 c.936C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 0.86 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.88 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834570 c.1029C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834606 c.1065C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.95 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.93 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.95 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 1.0 linezolid
tsnR 1853361 c.-245T>C upstream_gene_variant 0.96 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 0.9 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.97 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.96 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.97 linezolid
tsnR 1853441 c.-165C>T upstream_gene_variant 0.95 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.96 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.75 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.7 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.91 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.91 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.82 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.89 linezolid
tsnR 1853484 c.-122_-121delAGinsGC upstream_gene_variant 0.85 linezolid
tlyA 1917951 c.12T>C synonymous_variant 0.92 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917981 c.42G>C synonymous_variant 1.0 capreomycin
tlyA 1917984 c.45C>T synonymous_variant 0.9 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.91 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.91 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>C synonymous_variant 0.9 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.9 capreomycin
tlyA 1918008 c.69C>T synonymous_variant 0.7 capreomycin
tlyA 1918026 c.87C>T synonymous_variant 0.7 capreomycin
tlyA 1918029 c.90C>A synonymous_variant 0.7 capreomycin
tlyA 1918035 c.96G>C synonymous_variant 0.8 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.8 capreomycin
bacA 2063254 p.Glu492Ala missense_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063259 p.Glu490Asp missense_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063265 p.Gly488Glu missense_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063271 c.1458G>C synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063275 p.His485Cys missense_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063280 c.1449C>G synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063289 c.1440A>C synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063292 c.1437C>T synonymous_variant 0.88 streptomycin
kanamycin Not assoc w R - Interim
capreomycin
amikacin
bacA 2063295 c.1434C>G synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063307 c.1422G>C synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063310 c.1419G>T synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063520 c.1209G>A synonymous_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063523 c.1206T>C synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063538 c.1191A>C synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063541 c.1188A>C synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063544 c.1185C>G synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063553 c.1176G>T synonymous_variant 0.84 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063556 c.1173T>C synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063565 c.1164C>T synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063588 c.1141T>C synonymous_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063610 c.1117_1119delTCCinsGA frameshift_variant&stop_gained 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063613 c.1116T>G synonymous_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063625 c.1104G>T synonymous_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063628 c.1101C>G synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063640 c.1089C>T synonymous_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063648 p.Gln361Lys missense_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
bacA 2063649 c.1080G>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063658 c.1069_1071delTTAinsCG frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
ndh 2101744 p.Asp433Glu missense_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2101756 c.1287G>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101762 c.1281C>T synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2101765 c.1278C>G synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>A synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>C synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.9 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101795 c.1248G>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101808 p.Thr412Ser missense_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101830 p.Ile405Val missense_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2102200 c.843G>A synonymous_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102206 c.837G>C synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2102212 c.831G>T synonymous_variant 0.81 ethionamide
delamanid
isoniazid
ndh 2102218 c.825C>A synonymous_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>T synonymous_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2102230 c.813G>T synonymous_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.77 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102239 c.804C>T synonymous_variant 0.81 ethionamide
delamanid
isoniazid
ndh 2102244 c.799C>A synonymous_variant 0.81 ethionamide
delamanid
isoniazid
ndh 2102247 p.Val266Ile missense_variant 0.81 ethionamide
delamanid
isoniazid
ndh 2102275 c.768C>G synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102334 p.Gln237Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102337 c.706T>C synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid
isoniazid
ndh 2102344 c.699T>G synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102350 c.693G>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
katG 2155029 c.1083C>G synonymous_variant 0.73 isoniazid
katG 2155032 c.1080T>C synonymous_variant 0.73 isoniazid Not assoc w R - Interim
katG 2155035 c.1077C>G synonymous_variant 0.73 isoniazid
katG 2155050 c.1062C>G synonymous_variant 0.73 isoniazid
katG 2155054 p.Tyr353Phe missense_variant 0.73 isoniazid
katG 2155056 c.1056A>G synonymous_variant 0.73 isoniazid
katG 2155062 c.1050T>C synonymous_variant 0.73 isoniazid
katG 2155068 c.1044T>C synonymous_variant 0.73 isoniazid
katG 2155071 c.1041T>C synonymous_variant 0.73 isoniazid
katG 2155074 c.1038C>T synonymous_variant 0.64 isoniazid
katG 2155080 c.1032G>C synonymous_variant 0.73 isoniazid
katG 2155581 c.531C>A synonymous_variant 0.9 isoniazid
katG 2155590 c.522A>G synonymous_variant 0.91 isoniazid
katG 2155596 c.516G>C synonymous_variant 0.64 isoniazid
katG 2155605 c.507C>T synonymous_variant 0.64 isoniazid
katG 2155608 c.504C>G synonymous_variant 0.64 isoniazid
katG 2155617 c.495T>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
katG 2155620 c.492G>C synonymous_variant 0.58 isoniazid
katG 2155623 c.489C>T synonymous_variant 0.83 isoniazid
katG 2155626 c.486G>C synonymous_variant 0.83 isoniazid
katG 2155632 c.480A>C synonymous_variant 0.83 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.86 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.92 isoniazid Uncertain significance
katG 2155691 c.421T>C synonymous_variant 0.7 isoniazid
katG 2155692 c.420C>T synonymous_variant 0.6 isoniazid
katG 2155695 p.Ala139Val missense_variant 0.7 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.64 isoniazid
katG 2155710 c.402C>T synonymous_variant 0.55 isoniazid
katG 2155716 c.396T>C synonymous_variant 0.7 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.7 isoniazid
pncA 2289925 c.-684T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289937 c.-696C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289945 c.-704T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289958 c.-717T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289964 c.-723C>A upstream_gene_variant 1.0 pyrazinamide
pncA 2289967 c.-726C>A upstream_gene_variant 1.0 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.97 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.97 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.88 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.78 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 0.93 pyrazinamide
kasA 2517926 c.-189G>A upstream_gene_variant 0.82 isoniazid
kasA 2517956 c.-159G>A upstream_gene_variant 0.93 isoniazid
kasA 2517965 c.-150C>T upstream_gene_variant 0.78 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.9 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.88 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.78 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.93 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.86 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.94 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.95 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.95 isoniazid
kasA 2518183 c.69G>T synonymous_variant 0.95 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.96 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.93 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.9 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.85 isoniazid
kasA 2518459 c.345T>G synonymous_variant 0.85 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.85 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.89 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.52 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.86 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.87 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.75 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.9 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.9 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.9 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.89 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.91 isoniazid
kasA 2518537 c.423C>G synonymous_variant 0.79 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.91 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.78 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.93 isoniazid
kasA 2518579 c.465T>A synonymous_variant 0.92 isoniazid
kasA 2518582 c.468G>T synonymous_variant 0.88 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.96 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.88 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.93 isoniazid
kasA 2518618 c.504G>T synonymous_variant 0.84 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.8 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.77 isoniazid
kasA 2518645 c.531G>A synonymous_variant 0.78 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.77 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.89 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.9 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.71 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.89 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.87 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.74 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.8 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.98 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.87 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.96 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.96 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.96 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.98 isoniazid
kasA 2518834 c.720C>T synonymous_variant 0.91 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.96 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.94 isoniazid
kasA 2518873 c.759C>T synonymous_variant 0.81 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.9 isoniazid
kasA 2518882 c.768C>A synonymous_variant 0.79 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.89 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.81 isoniazid
kasA 2518909 c.795G>A synonymous_variant 0.75 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.75 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.84 isoniazid
kasA 2518933 c.819C>T synonymous_variant 0.6 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.64 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.64 isoniazid
ahpC 2726285 c.93C>T synonymous_variant 0.53 isoniazid
ahpC 2726288 c.96C>G synonymous_variant 0.53 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 0.71 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.78 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.78 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.78 isoniazid
ahpC 2726322 c.130_132delCCAinsGC frameshift_variant&missense_variant 0.58 isoniazid Uncertain significance
ahpC 2726348 c.156T>C synonymous_variant 0.94 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726612 c.420C>G synonymous_variant 0.8 isoniazid
ahpC 2726633 c.441C>T synonymous_variant 0.87 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.81 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.81 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 0.83 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.76 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.81 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.81 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.81 isoniazid
ahpC 2726693 c.501C>A synonymous_variant 0.81 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.81 isoniazid
ahpC 2726709 c.517C>T synonymous_variant 0.73 isoniazid
folC 2746308 p.Arg431Ser missense_variant 1.0 para-aminosalicylic_acid
folC 2746330 c.1269G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746335 p.Gly422Ser missense_variant 1.0 para-aminosalicylic_acid
folC 2746344 c.1255C>T synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746345 c.1254G>T synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746351 c.1246_1248delGCCinsTG frameshift_variant&missense_variant 0.92 para-aminosalicylic_acid
folC 2746360 c.1239T>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746363 c.1236G>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746375 c.1224G>C synonymous_variant 0.85 para-aminosalicylic_acid
folC 2746378 c.1221G>A synonymous_variant 0.85 para-aminosalicylic_acid
folC 2746387 c.1212C>G synonymous_variant 0.7 para-aminosalicylic_acid
folC 2746576 c.1023C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746584 c.1015T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746588 c.1011C>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2746594 c.1005T>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2746599 p.Thr334Ala missense_variant 0.93 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746612 c.987C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746621 c.978C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746627 p.Asp324Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 1.0 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 0.9 para-aminosalicylic_acid
folC 2747473 p.Arg42Lys missense_variant 0.75 para-aminosalicylic_acid
folC 2747491 c.108A>G synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747497 c.102C>G synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747500 c.99A>G synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747503 c.96T>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747509 c.90T>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747745 c.-147A>C upstream_gene_variant 0.75 para-aminosalicylic_acid
folC 2747748 c.-150C>G upstream_gene_variant 0.94 para-aminosalicylic_acid
folC 2747751 c.-154_-153delGCinsCA upstream_gene_variant 0.94 para-aminosalicylic_acid
folC 2747759 c.-161T>C upstream_gene_variant 0.75 para-aminosalicylic_acid
folC 2747760 c.-162G>C upstream_gene_variant 0.92 para-aminosalicylic_acid
folC 2747772 c.-174C>A upstream_gene_variant 0.93 para-aminosalicylic_acid
folC 2747781 c.-183G>A upstream_gene_variant 0.78 para-aminosalicylic_acid
folC 2747790 c.-192G>C upstream_gene_variant 0.74 para-aminosalicylic_acid
Rv2477c 2782418 p.Val542Ala missense_variant 0.86 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2782429 c.1614A>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782432 c.1609_1611delGTGinsAC frameshift_variant&missense_variant 0.75 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782450 c.1593C>A synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782510 c.1533G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.89 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782570 c.1473C>T synonymous_variant 0.75 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782720 c.1323T>C synonymous_variant 0.7 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782876 c.1167G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782887 c.1156C>T synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782913 p.Ser377Thr missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782966 c.1077C>T synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782978 c.1065C>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783026 c.1017C>T synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783038 c.1003_1005delGCCinsAG frameshift_variant&missense_variant 0.69 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783071 c.972C>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>A synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783098 c.945C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.9 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783203 c.840C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783287 c.756C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783293 p.Glu250Asp missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783341 c.702C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783356 c.687C>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783551 c.492G>A synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783554 c.489C>T synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783566 c.477C>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783629 c.414C>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783746 c.297G>A synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783770 c.273G>A synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.84 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784016 c.27G>A synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784051 c.-9C>A upstream_gene_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996611 c.-128G>C upstream_gene_variant 0.7 capreomycin
Rv2681 2996906 c.168A>G synonymous_variant 0.73 capreomycin
Rv2681 2996921 c.183G>A synonymous_variant 0.78 capreomycin
Rv2681 2996930 c.192C>T synonymous_variant 0.79 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 0.89 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 0.89 capreomycin
Rv2681 2996951 c.213C>T synonymous_variant 0.83 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 0.85 capreomycin
Rv2681 2996976 c.238_240delGCCinsTG frameshift_variant&missense_variant 0.69 capreomycin Uncertain significance
Rv2681 2996987 c.249A>G synonymous_variant 0.92 capreomycin
Rv2681 2996990 c.252G>C synonymous_variant 0.92 capreomycin
Rv2681 2997002 c.264C>G synonymous_variant 0.7 capreomycin
Rv2681 2997065 c.327G>A synonymous_variant 0.92 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 0.89 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 0.95 capreomycin
Rv2681 2997107 c.369C>G synonymous_variant 0.9 capreomycin
Rv2681 2997113 c.375C>G synonymous_variant 0.86 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 0.91 capreomycin
Rv2681 2997128 c.390A>G synonymous_variant 0.91 capreomycin
Rv2681 2997134 c.396A>C synonymous_variant 0.85 capreomycin
Rv2681 2997137 c.399C>T synonymous_variant 0.76 capreomycin
Rv2681 2997146 c.408G>A synonymous_variant 0.72 capreomycin
Rv2681 2997149 c.411T>G synonymous_variant 0.83 capreomycin
Rv2681 2997158 c.420C>G synonymous_variant 0.83 capreomycin
Rv2681 2997794 p.Asp352Glu missense_variant 0.91 capreomycin
Rv2681 2997804 p.Ala356Ser missense_variant 0.91 capreomycin
Rv2752c 3064911 c.1281C>G synonymous_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>G synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064932 c.1260T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064947 c.1245A>G synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064950 c.1242C>G synonymous_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064958 p.Ser412Arg missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064962 c.1230C>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064973 p.Ala407Ser missense_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064995 c.1197C>G synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065007 c.1185G>C synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065013 c.1179G>C synonymous_variant 0.74 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065016 c.1174_1176delAACinsCT frameshift_variant&missense_variant 0.74 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065028 c.1162_1164delGTGinsAT frameshift_variant&missense_variant 0.74 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065031 c.1161G>C synonymous_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065040 c.1152C>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.74 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065052 c.1140G>A synonymous_variant 0.74 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065229 c.963G>C synonymous_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065249 c.943T>C synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065288 c.904T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065292 c.900T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065295 p.Gln299Arg missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065306 p.Ala296Pro missense_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065311 p.Thr294Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065313 c.879A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065397 c.795G>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065418 c.774A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065427 c.765G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065451 c.741G>A synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065466 c.726G>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065475 c.717C>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065481 c.711T>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065496 c.696G>C synonymous_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065517 c.673_675delCTCinsTG frameshift_variant&synonymous_variant 0.89 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065532 c.660A>G synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065553 c.639A>G synonymous_variant 0.91 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065562 c.630T>C synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065568 c.622_624delATCinsTA frameshift_variant&synonymous_variant 0.83 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065576 p.Ala206Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065577 c.615C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065595 p.Leu199Phe missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065607 c.585C>G synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065973 p.Asp73Glu missense_variant 0.59 ethambutol Uncertain significance
moxifloxacin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065979 c.213T>C synonymous_variant 0.74 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065985 c.207C>T synonymous_variant 0.52 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065988 c.204A>G synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.76 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066002 p.Met64Leu missense_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066069 c.121_123delTTGinsCA frameshift_variant&missense_variant 0.69 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066075 c.117A>G synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066084 c.108C>T synonymous_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066096 c.96G>C synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Ser missense_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066132 c.60G>A synonymous_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066135 c.57C>A synonymous_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066435 c.-244T>C upstream_gene_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066452 c.-261T>A upstream_gene_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-268T>C upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-274G>A upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066476 c.-285C>G upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066480 c.-291_-289delGCCinsTT upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-311_-310delCGinsTC upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066543 c.-352C>A upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066556 c.-365C>T upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>T upstream_gene_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066765 c.-574G>T upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066804 c.-613G>T upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066864 c.-673C>T upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>C upstream_gene_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067205 c.741G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067211 c.735G>A synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067220 c.726G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067223 c.723G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067243 c.703C>T synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.86 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067382 c.564C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067388 c.558C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.5 para-aminosalicylic_acid
thyX 3067612 p.Lys112Gln missense_variant 0.83 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067643 c.303C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067649 c.297C>T synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067658 c.288C>T synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067667 c.279G>C synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067706 c.240C>T synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067715 c.231C>T synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067724 c.222G>A synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067760 c.184_186delCGGinsAC frameshift_variant&missense_variant 0.88 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.92 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 0.81 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067849 p.Pro33Ser missense_variant 0.82 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.88 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067935 p.Thr4Ile missense_variant 0.83 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073872 c.598_600delATCinsGG frameshift_variant&missense_variant 0.88 para-aminosalicylic_acid
thyA 3073888 p.Ser195Glu missense_variant 0.87 para-aminosalicylic_acid
thyA 3073890 c.580_582delTTGinsCC frameshift_variant&missense_variant 0.87 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.88 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073926 c.546G>A synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3073983 c.489C>T synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074022 c.450C>T synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3074046 c.426G>A synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.73 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.75 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 0.6 para-aminosalicylic_acid
thyA 3074190 c.282C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyA 3074199 c.273G>T synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.86 para-aminosalicylic_acid
thyA 3074208 c.264C>A synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3074214 p.Asp86Ala missense_variant 0.86 para-aminosalicylic_acid
thyA 3074253 c.219C>T synonymous_variant 0.79 para-aminosalicylic_acid
ald 3087704 c.885T>C synonymous_variant 0.73 cycloserine
ald 3087726 p.Ala303Ser missense_variant 0.67 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.67 cycloserine
lpqB 3623356 p.Leu519Ile missense_variant 0.77 bedaquiline
rifampicin
lpqB 3623360 c.1551A>G synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3623423 c.1488C>G synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623428 c.1483T>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3623459 c.1452G>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623465 c.1446G>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623472 p.Tyr480Phe missense_variant 0.71 bedaquiline
rifampicin
lpqB 3623480 c.1431C>G synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623484 p.Phe476Tyr missense_variant 0.75 bedaquiline
rifampicin
lpqB 3623489 c.1422C>G synonymous_variant 0.87 bedaquiline
rifampicin
lpqB 3623492 c.1419T>C synonymous_variant 0.87 bedaquiline
rifampicin
lpqB 3623512 p.Gly467Ser missense_variant 0.82 bedaquiline
rifampicin
lpqB 3624071 c.840C>T synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624074 c.837G>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624077 c.834G>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624086 c.825C>T synonymous_variant 0.94 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624094 c.817A>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624100 c.811T>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624119 c.792C>A synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624131 c.780G>A synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.96 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624173 c.738A>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624188 c.723G>T synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624194 c.717C>G synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624197 c.714C>T synonymous_variant 0.81 bedaquiline
rifampicin
lpqB 3624200 c.711A>G synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3624204 p.Ser236Asn missense_variant 0.88 bedaquiline
rifampicin
lpqB 3624209 c.702A>C synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3624212 c.699C>G synonymous_variant 0.81 bedaquiline
rifampicin
lpqB 3624224 c.687T>C synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624331 c.580C>T synonymous_variant 0.54 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 0.71 bedaquiline
rifampicin
lpqB 3624346 p.Ser189Pro missense_variant 0.57 bedaquiline
rifampicin
lpqB 3624356 c.555C>T synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624362 c.549G>A synonymous_variant 0.57 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624368 c.543C>G synonymous_variant 0.57 bedaquiline
rifampicin
lpqB 3624377 c.534C>G synonymous_variant 0.53 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624389 c.522C>G synonymous_variant 0.56 bedaquiline
rifampicin
lpqB 3624401 c.510C>T synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 0.46 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624650 c.261G>A synonymous_variant 0.86 bedaquiline
rifampicin
lpqB 3624656 c.255C>T synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624680 c.231T>G synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3624683 c.228G>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 0.94 bedaquiline
rifampicin Uncertain significance
lpqB 3624701 c.210T>C synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624704 c.207G>T synonymous_variant 0.84 bedaquiline
rifampicin
lpqB 3624707 c.204G>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3624731 c.180C>A synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 0.81 bedaquiline
rifampicin Uncertain significance
lpqB 3624770 c.141T>C synonymous_variant 0.76 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 0.76 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 0.76 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 0.76 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 0.72 bedaquiline
rifampicin
lpqB 3625054 c.-144C>T upstream_gene_variant 0.56 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625080 c.-170C>A upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrB 3625087 c.1525_1527delGCCinsTG frameshift_variant&missense_variant 0.6 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625090 c.1524C>T synonymous_variant 0.56 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625093 p.Glu507Asp missense_variant 0.56 bedaquiline
rifampicin
mtrB 3625111 c.1503G>A synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625123 c.-213T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.83 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 0.77 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625243 c.-333T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625252 c.-342G>T upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625279 c.-369C>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3625282 c.1332C>A synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625313 p.Arg434Lys missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625315 c.-405G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625327 c.-417A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625333 c.-423C>T upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625579 c.-669A>G upstream_gene_variant 0.72 bedaquiline
rifampicin
lpqB 3625588 c.-678G>A upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 0.81 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.85 bedaquiline
rifampicin
lpqB 3625621 c.-711G>C upstream_gene_variant 0.63 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.86 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 0.89 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625708 c.906C>T synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625806 c.808A>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625852 c.762A>G synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625888 c.726G>A synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625909 c.-999T>A upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.92 bedaquiline
rifampicin
mtrB 3625930 c.684C>A synonymous_variant 0.9 bedaquiline
rifampicin
mtrB 3625936 c.678C>G synonymous_variant 0.72 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625942 c.672C>G synonymous_variant 0.8 bedaquiline
rifampicin
mtrB 3625945 c.669A>G synonymous_variant 0.8 bedaquiline
rifampicin
mtrB 3626095 p.Glu173Asp missense_variant 0.8 bedaquiline
rifampicin
mtrB 3626101 p.Gln171His missense_variant 0.8 bedaquiline
rifampicin
mtrB 3626125 c.489C>G synonymous_variant 0.7 bedaquiline
rifampicin
mtrB 3626684 c.-71G>T upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3626720 c.-107G>A upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3626735 c.-122C>T upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626746 c.-133C>A upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrA 3626765 c.585C>T synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.92 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrA 3626869 c.481C>T synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626876 c.-263A>G upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626891 c.-278G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626894 c.-281C>T upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626912 c.-299T>G upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627023 c.-410C>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627065 c.-452G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627101 c.249C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627137 c.213G>A synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627167 c.-554T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627194 c.154_156delCTGinsTA frameshift_variant&synonymous_variant 0.88 bedaquiline
rifampicin
mtrA 3627208 c.142C>T synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627263 c.-650C>T upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.74 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627342 p.Thr3Phe missense_variant 0.89 bedaquiline
rifampicin
mtrA 3627345 p.Asp2Val missense_variant 0.89 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
fbiB 3642560 c.1026T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3642566 c.1032A>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3642609 c.1075_1076delAGinsTC synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiB 3642623 c.1089C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiB 3642659 c.1125C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiB 3642711 p.Leu393Val missense_variant 0.8 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
alr 3841037 c.384G>C synonymous_variant 0.85 cycloserine
alr 3841069 p.Ile118Val missense_variant 0.77 cycloserine
alr 3841070 c.351C>T synonymous_variant 0.56 cycloserine
alr 3841079 c.342T>C synonymous_variant 0.8 cycloserine
alr 3841082 c.339G>A synonymous_variant 0.5 cycloserine
alr 3841088 c.333C>G synonymous_variant 0.5 cycloserine
alr 3841100 c.321A>G synonymous_variant 0.83 cycloserine
alr 3841232 c.189G>C synonymous_variant 0.83 cycloserine
alr 3841240 p.Leu61Val missense_variant 0.83 cycloserine
alr 3841248 p.His58Ser missense_variant 0.77 cycloserine
alr 3841250 c.171C>G synonymous_variant 0.77 cycloserine
alr 3841256 p.His55Gln missense_variant 0.77 cycloserine
alr 3841262 c.157_159delCGTinsTC frameshift_variant&missense_variant 0.77 cycloserine
alr 3841270 p.Val51Leu missense_variant 0.85 cycloserine
alr 3841283 c.138A>G synonymous_variant 0.85 cycloserine
alr 3841289 c.132T>C synonymous_variant 0.85 cycloserine
alr 3841298 c.123T>C synonymous_variant 0.77 cycloserine
alr 3841301 c.120G>T synonymous_variant 0.73 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 1.0 rifampicin
rpoA 3877506 p.Gly334Ala missense_variant 0.81 rifampicin
rpoA 3877513 p.Thr332Asn missense_variant 1.0 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.85 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.86 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.76 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877746 c.762G>T synonymous_variant 0.86 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877829 p.Val227Ile missense_variant 0.93 rifampicin
rpoA 3877839 c.669G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.96 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.96 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.96 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.95 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.97 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 0.9 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877983 c.525C>T synonymous_variant 0.92 rifampicin
rpoA 3877986 c.522G>C synonymous_variant 0.98 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.98 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878055 c.453A>G synonymous_variant 0.96 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.95 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.89 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.91 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.89 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.94 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.96 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>T synonymous_variant 1.0 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.89 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.89 rifampicin Uncertain significance
rpoA 3878148 c.360C>T synonymous_variant 0.91 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878166 c.342C>G synonymous_variant 0.89 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.75 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.97 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.96 rifampicin
rpoA 3878307 c.201C>G synonymous_variant 0.9 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878364 c.144A>T synonymous_variant 0.96 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.89 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.88 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.88 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878415 c.93C>T synonymous_variant 0.94 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.8 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.93 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.89 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 0.75 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.84 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.82 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.8 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 0.92 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 0.92 rifampicin
rpoA 3878716 c.-209C>G upstream_gene_variant 0.76 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.89 rifampicin
rpoA 3878728 c.-221G>A upstream_gene_variant 0.89 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.71 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.71 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.88 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.88 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.86 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.86 rifampicin
rpoA 3878769 c.-262C>T upstream_gene_variant 0.8 rifampicin
rpoA 3878785 c.-278T>C upstream_gene_variant 0.95 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.9 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.94 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.97 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.93 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878836 c.-331_-329delAAGinsGGC upstream_gene_variant 0.9 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.98 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoA 3878935 c.-428C>T upstream_gene_variant 0.98 rifampicin
rpoA 3878938 c.-431T>G upstream_gene_variant 0.98 rifampicin
rpoA 3878962 c.-455G>T upstream_gene_variant 0.98 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 0.96 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 0.98 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.98 rifampicin
rpoA 3879019 c.-512T>C upstream_gene_variant 0.96 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.98 rifampicin
rpoA 3879033 c.-526C>T upstream_gene_variant 0.96 rifampicin
rpoA 3879040 c.-535_-533delGTGinsTCC upstream_gene_variant 0.96 rifampicin
rpoA 3879050 c.-543A>C upstream_gene_variant 0.94 rifampicin
rpoA 3879070 c.-563G>A upstream_gene_variant 0.95 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.98 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.98 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.98 rifampicin
rpoA 3879097 c.-590C>T upstream_gene_variant 0.9 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879124 c.-617G>C upstream_gene_variant 0.92 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.99 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.99 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.98 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.96 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.9 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.9 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.89 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.89 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.9 delamanid
pretomanid
ddn 3986637 c.-207C>T upstream_gene_variant 0.88 delamanid
pretomanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.86 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.9 delamanid
pretomanid
ddn 3986655 c.-189A>T upstream_gene_variant 0.9 delamanid
pretomanid
ddn 3986665 c.-179G>C upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.93 delamanid
pretomanid
ddn 3986681 c.-163C>G upstream_gene_variant 0.9 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.85 delamanid
pretomanid
ddn 3986696 c.-148G>T upstream_gene_variant 0.79 delamanid
pretomanid
ddn 3986705 c.-139C>G upstream_gene_variant 0.78 delamanid
pretomanid
clpC1 4038212 c.2493T>C synonymous_variant 0.92 pyrazinamide
clpC1 4038218 c.2487G>A synonymous_variant 0.88 pyrazinamide
clpC1 4038239 c.2466T>A synonymous_variant 0.89 pyrazinamide
clpC1 4038248 c.2457C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038255 p.Val817Thr missense_variant 0.9 pyrazinamide
clpC1 4038260 p.Asp815Glu missense_variant 0.86 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.92 pyrazinamide
clpC1 4038274 p.Gly811Ser missense_variant 0.92 pyrazinamide
clpC1 4038275 c.2430A>G synonymous_variant 0.88 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.9 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038320 c.2385G>A synonymous_variant 0.88 pyrazinamide
clpC1 4038326 c.2379G>A synonymous_variant 0.84 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038433 c.2272C>T synonymous_variant 0.97 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.77 pyrazinamide
clpC1 4038440 c.2265C>G synonymous_variant 0.77 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.97 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038458 c.2247G>C synonymous_variant 0.8 pyrazinamide
clpC1 4038461 c.2244G>C synonymous_variant 0.8 pyrazinamide
clpC1 4038486 p.Gly740Thr missense_variant 0.76 pyrazinamide
clpC1 4038498 p.Ser736Thr missense_variant 0.8 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.81 pyrazinamide
clpC1 4038533 p.Arg724Lys missense_variant 0.81 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.98 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.98 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.85 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.7 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.96 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038683 c.2022T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038692 c.2013C>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.76 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.73 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.68 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.9 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.77 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.65 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.69 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.92 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039046 c.1659C>A synonymous_variant 0.79 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039070 c.1635G>A synonymous_variant 0.86 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039128 p.Lys526Arg missense_variant 0.87 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039158 p.Lys516Arg missense_variant 0.83 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.9 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039256 c.1449G>A synonymous_variant 0.86 pyrazinamide
clpC1 4039268 c.1437C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039274 c.1431G>T synonymous_variant 0.91 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 0.73 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.62 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.52 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4039346 c.1359G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4039364 c.1341C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.86 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.8 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039514 c.1191C>T synonymous_variant 0.76 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 0.71 pyrazinamide
clpC1 4039553 c.1152C>T synonymous_variant 0.71 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.83 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4039610 c.1095G>T synonymous_variant 0.93 pyrazinamide
clpC1 4039613 c.1092C>T synonymous_variant 0.82 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039706 c.999G>A synonymous_variant 0.86 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039808 c.897G>A synonymous_variant 0.58 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.94 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039982 c.723G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039985 c.720G>A synonymous_variant 0.82 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 0.89 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.86 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.87 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4040048 c.657C>T synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.610_612delCTCinsTG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.95 pyrazinamide
clpC1 4040213 c.492T>G synonymous_variant 0.98 pyrazinamide
clpC1 4040225 c.480A>G synonymous_variant 0.98 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040237 c.468C>A synonymous_variant 0.98 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 0.98 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.97 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040314 c.391C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.78 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.83 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.83 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.81 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.83 pyrazinamide
clpC1 4040372 c.333C>T synonymous_variant 0.72 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.62 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.62 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.73 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.292_294delCTTinsTG frameshift_variant&synonymous_variant 0.73 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.87 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.74 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.86 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040462 c.243C>G synonymous_variant 0.81 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040477 c.228G>A synonymous_variant 0.92 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.85 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040644 c.61A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.89 pyrazinamide
panD 4044108 c.174C>T synonymous_variant 0.71 pyrazinamide
panD 4044117 c.165G>C synonymous_variant 0.75 pyrazinamide
panD 4044120 c.162A>C synonymous_variant 0.75 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.75 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 0.76 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 0.73 pyrazinamide
panD 4044153 c.129G>A synonymous_variant 0.73 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
panD 4044162 c.120A>G synonymous_variant 0.75 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.75 pyrazinamide
panD 4044174 c.108C>G synonymous_variant 0.78 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.6 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.59 pyrazinamide
panD 4044204 c.78G>C synonymous_variant 0.69 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 0.83 pyrazinamide
panD 4044240 c.42G>C synonymous_variant 0.66 pyrazinamide
panD 4044246 c.36C>G synonymous_variant 0.66 pyrazinamide
panD 4044258 c.24G>A synonymous_variant 0.68 pyrazinamide
panD 4044264 c.18G>C synonymous_variant 0.72 pyrazinamide
panD 4044278 c.4T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
panD 4044284 c.-3C>T upstream_gene_variant 0.75 pyrazinamide
panD 4044287 c.-6A>G upstream_gene_variant 0.88 pyrazinamide
panD 4044294 c.-13A>C upstream_gene_variant 0.73 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.9 pyrazinamide
panD 4044728 c.-447C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044742 c.-461T>C upstream_gene_variant 0.9 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 0.75 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.94 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.91 pyrazinamide
panD 4044785 c.-504C>G upstream_gene_variant 0.71 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.92 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.72 pyrazinamide
panD 4044806 c.-525T>C upstream_gene_variant 0.79 pyrazinamide
panD 4044812 c.-531A>G upstream_gene_variant 0.79 pyrazinamide
panD 4044818 c.-539_-537delCCGinsGC upstream_gene_variant 0.77 pyrazinamide
panD 4044830 c.-549C>G upstream_gene_variant 0.76 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.76 pyrazinamide
panD 4044836 c.-555C>T upstream_gene_variant 0.79 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.88 pyrazinamide
panD 4044848 c.-567T>C upstream_gene_variant 0.8 pyrazinamide
panD 4044977 c.-696T>C upstream_gene_variant 0.95 pyrazinamide
panD 4045000 c.-719A>T upstream_gene_variant 1.0 pyrazinamide
panD 4045022 c.-741C>A upstream_gene_variant 0.95 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.98 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.97 pyrazinamide
panD 4045066 c.-785G>T upstream_gene_variant 0.93 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.93 pyrazinamide
panD 4045073 c.-792C>T upstream_gene_variant 0.93 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.93 pyrazinamide
panD 4045085 c.-804G>A upstream_gene_variant 0.92 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.92 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 0.9 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.9 pyrazinamide
panD 4045112 c.-831A>G upstream_gene_variant 0.92 pyrazinamide
glpK 4138535 c.1221T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138547 c.1209C>T synonymous_variant 0.61 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138550 c.1206C>T synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138564 c.1192C>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>A synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138615 p.Ile381Val missense_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>T synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 0.78 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138655 c.1101G>A synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138664 c.1092G>A synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138667 c.1089G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138747 c.1009C>T synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138751 c.1005T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139207 c.549T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139228 c.526_528delCCGinsGC frameshift_variant&missense_variant 0.88 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139231 c.525A>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139234 c.522C>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139242 c.514T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139243 c.513A>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139253 p.Asn168Ser missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139255 c.501G>A synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139270 c.486C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139273 c.483A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139276 c.480T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139282 c.474T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139285 c.471A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 0.93 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139600 c.156G>A synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139603 c.153C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139608 p.Leu50Met missense_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139611 p.Ile49Val missense_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139615 c.141G>A synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139627 c.129G>A synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139630 c.126C>T synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139636 c.120C>T synonymous_variant 0.84 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139642 c.114G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139651 p.His35Gln missense_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139675 c.81C>T synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239125 c.-738C>G upstream_gene_variant 0.83 ethambutol
embC 4239140 c.-723G>C upstream_gene_variant 0.89 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 0.93 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 0.93 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 0.92 ethambutol
embC 4239165 c.-698C>T upstream_gene_variant 0.92 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 0.92 ethambutol
embC 4239179 c.-684G>T upstream_gene_variant 0.92 ethambutol
embC 4239185 c.-678G>C upstream_gene_variant 0.9 ethambutol
embC 4239188 c.-675G>C upstream_gene_variant 0.89 ethambutol Uncertain significance
embC 4239198 c.-665C>T upstream_gene_variant 0.91 ethambutol
embC 4239293 c.-570G>C upstream_gene_variant 0.64 ethambutol
embC 4239294 c.-569T>C upstream_gene_variant 0.75 ethambutol
embC 4239301 c.-562G>C upstream_gene_variant 0.83 ethambutol
embC 4239305 c.-558G>C upstream_gene_variant 0.82 ethambutol
embC 4239329 c.-534C>T upstream_gene_variant 0.74 ethambutol
embC 4239336 c.-527T>C upstream_gene_variant 0.93 ethambutol
embC 4239341 c.-522G>A upstream_gene_variant 0.76 ethambutol
embC 4239344 c.-519G>C upstream_gene_variant 0.78 ethambutol
embC 4239350 c.-513G>C upstream_gene_variant 0.75 ethambutol
embC 4239377 c.-486C>T upstream_gene_variant 0.64 ethambutol
embC 4239378 c.-485T>C upstream_gene_variant 0.86 ethambutol
embC 4239383 c.-480C>G upstream_gene_variant 0.64 ethambutol
embC 4239466 c.-397G>C upstream_gene_variant 0.83 ethambutol
embC 4239475 c.-388G>A upstream_gene_variant 0.85 ethambutol Uncertain significance
embC 4239482 c.-381C>G upstream_gene_variant 0.88 ethambutol
embC 4239486 c.-377T>A upstream_gene_variant 0.89 ethambutol
embC 4239507 c.-356C>T upstream_gene_variant 0.8 ethambutol
embC 4239512 c.-351G>C upstream_gene_variant 0.95 ethambutol Uncertain significance
embC 4239514 c.-349A>T upstream_gene_variant 0.76 ethambutol
embC 4239518 c.-345C>T upstream_gene_variant 0.76 ethambutol
embC 4239530 c.-333C>A upstream_gene_variant 0.79 ethambutol
embC 4239533 c.-330T>C upstream_gene_variant 0.89 ethambutol
embC 4239540 c.-323_-321delTTGinsCC upstream_gene_variant 0.88 ethambutol
embC 4239545 c.-318G>C upstream_gene_variant 0.88 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 0.88 ethambutol
embC 4239566 c.-297G>C upstream_gene_variant 0.9 ethambutol
embC 4240267 c.405T>C synonymous_variant 0.79 ethambutol
embC 4240277 p.Leu139Val missense_variant 0.81 ethambutol
embC 4240282 c.420C>G synonymous_variant 0.76 ethambutol
embC 4240288 c.426C>G synonymous_variant 0.76 ethambutol
embC 4240292 c.430C>T synonymous_variant 0.76 ethambutol
embC 4240296 p.Ser145Asn missense_variant 0.76 ethambutol
embC 4240307 c.445_447delGGCinsAT frameshift_variant&missense_variant 0.72 ethambutol
embC 4240313 p.Thr151Ala missense_variant 0.72 ethambutol
embC 4240324 c.462G>A synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embC 4240330 c.468A>C synonymous_variant 0.78 ethambutol
embC 4240355 p.Ala165Thr missense_variant 0.8 ethambutol Uncertain significance
embC 4240543 c.681G>C synonymous_variant 0.86 ethambutol
embC 4240561 c.699C>G synonymous_variant 0.86 ethambutol
embC 4240574 c.712_714delGTAinsCG frameshift_variant&missense_variant 0.92 ethambutol
embC 4240578 p.Ala239Val missense_variant 0.92 ethambutol
embC 4240582 c.720C>G synonymous_variant 0.92 ethambutol
embC 4240587 p.Gly242Ala missense_variant 0.92 ethambutol
embC 4240592 c.730_732delGCCinsTG frameshift_variant&missense_variant 0.92 ethambutol
embC 4240598 c.736_738delGTGinsAC frameshift_variant&missense_variant 0.92 ethambutol
embC 4240615 c.753G>C synonymous_variant 0.86 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.82 ethambutol
embC 4240648 c.786C>T synonymous_variant 0.83 ethambutol
embC 4240657 c.795G>C synonymous_variant 0.94 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.93 ethambutol Not assoc w R
embC 4240678 c.816T>C synonymous_variant 0.91 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.92 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.91 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4240703 c.841C>T synonymous_variant 0.83 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.98 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.96 ethambutol
embC 4240822 c.960C>G synonymous_variant 0.95 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.94 ethambutol
embC 4240861 c.999G>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embC 4240867 c.1005T>C synonymous_variant 0.95 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.97 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.97 ethambutol Uncertain significance
embC 4240886 p.Ile342Val missense_variant 0.97 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.96 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.96 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.96 ethambutol
embC 4240921 c.1059C>G synonymous_variant 1.0 ethambutol
embC 4240924 c.1062C>G synonymous_variant 1.0 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.96 ethambutol
embC 4240951 c.1089C>G synonymous_variant 0.92 ethambutol
embC 4240954 p.Ile364Met missense_variant 0.92 ethambutol
embC 4240966 c.1104G>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4240969 c.1107C>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4240978 c.1116G>A synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4240979 p.Thr373Gln missense_variant 0.92 ethambutol
embC 4240983 p.Ser374Asn missense_variant 0.88 ethambutol
embC 4240990 c.1128A>C synonymous_variant 0.9 ethambutol
embC 4240996 c.1134G>C synonymous_variant 0.88 ethambutol
embC 4241002 c.1140G>C synonymous_variant 0.92 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.91 ethambutol
embC 4241023 c.1161T>C synonymous_variant 0.94 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.98 ethambutol
embC 4241053 c.1191G>T synonymous_variant 0.98 ethambutol
embC 4241065 c.1203C>T synonymous_variant 0.84 ethambutol
embC 4241071 c.1209C>G synonymous_variant 0.84 ethambutol
embC 4241104 c.1242G>A synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 0.97 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4241161 c.1299C>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.88 ethambutol
embC 4241167 c.1305C>G synonymous_variant 0.96 ethambutol
embC 4241179 c.1317G>A synonymous_variant 0.85 ethambutol
embC 4241185 c.1323G>C synonymous_variant 0.94 ethambutol
embC 4241188 c.1326C>A synonymous_variant 0.89 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.93 ethambutol
embC 4241248 c.1386G>C synonymous_variant 0.96 ethambutol
embC 4241251 c.1389T>C synonymous_variant 0.96 ethambutol
embC 4241256 p.Arg465Thr missense_variant 0.95 ethambutol Uncertain significance
embC 4241268 p.Val469Ala missense_variant 0.95 ethambutol
embC 4241275 c.1413A>G synonymous_variant 0.94 ethambutol
embC 4241279 c.1417_1419delGTGinsAC frameshift_variant&missense_variant 0.93 ethambutol
embC 4241288 c.1426_1428delATCinsCG frameshift_variant&missense_variant 0.91 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.69 ethambutol
embC 4241394 p.Lys511Ser missense_variant 0.86 ethambutol
embC 4241419 c.1557C>T synonymous_variant 0.71 ethambutol
embC 4241443 c.1581C>G synonymous_variant 0.68 ethambutol
embC 4241449 c.1587C>A synonymous_variant 0.88 ethambutol
embC 4241453 c.1591_1593delATCinsGT frameshift_variant&missense_variant 0.9 ethambutol
embC 4241470 c.1608C>G synonymous_variant 0.62 ethambutol
embC 4241989 c.2127A>G synonymous_variant 0.91 ethambutol
embC 4241995 c.2133C>G synonymous_variant 0.92 ethambutol
embC 4242002 p.Leu714Val missense_variant 0.93 ethambutol
embC 4242011 c.2149_2151delCTTinsGG frameshift_variant&missense_variant 0.93 ethambutol
embC 4242024 p.Val721Ala missense_variant 0.94 ethambutol
embC 4242036 p.Gln725Leu missense_variant 0.95 ethambutol
embC 4242045 p.Ile728Thr missense_variant 0.95 ethambutol
embC 4242047 c.2185_2187delTCCinsGG frameshift_variant&missense_variant 0.95 ethambutol
embC 4242070 c.2208T>C synonymous_variant 0.95 ethambutol
embC 4242073 c.2211C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4242079 c.2217T>C synonymous_variant 0.95 ethambutol
embC 4242085 c.2223A>G synonymous_variant 0.94 ethambutol
embC 4242091 c.2229T>G synonymous_variant 0.92 ethambutol
embC 4242092 p.Leu744Val missense_variant 0.92 ethambutol
embC 4242100 c.2238C>G synonymous_variant 0.86 ethambutol
embC 4242104 c.2242_2244delACCinsTG frameshift_variant&missense_variant 0.92 ethambutol
embC 4242112 c.2250G>A synonymous_variant 1.0 ethambutol
embC 4242121 p.Glu753Asp missense_variant 1.0 ethambutol
embA 4244378 c.1146G>A synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embA 4244919 c.1687_1689delCTCinsTG frameshift_variant&missense_variant 0.75 ethambutol Uncertain significance
embA 4244933 c.1701A>G synonymous_variant 0.86 ethambutol
embA 4244939 c.1707G>A synonymous_variant 0.76 ethambutol
embA 4244945 c.1713C>A synonymous_variant 0.79 ethambutol
embA 4244946 c.1714_1716delGTGinsAC frameshift_variant&missense_variant 0.79 ethambutol Uncertain significance
embA 4244957 c.1725C>T synonymous_variant 0.89 ethambutol
embA 4244960 c.1728A>G synonymous_variant 0.89 ethambutol
embA 4244969 c.1737G>A synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embA 4244972 c.1740G>T synonymous_variant 0.86 ethambutol
embA 4244973 p.Ala581Thr missense_variant 0.86 ethambutol Uncertain significance
embA 4244980 p.Val583Ala missense_variant 0.88 ethambutol
embA 4244982 c.1750T>C synonymous_variant 0.88 ethambutol
embA 4245003 p.Thr591Ala missense_variant 0.87 ethambutol Uncertain significance
embA 4245006 c.1774_1776delTTTinsCG frameshift_variant&missense_variant 0.85 ethambutol Uncertain significance
embA 4245014 c.1782C>G synonymous_variant 0.83 ethambutol
embA 4245023 c.1791A>G synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embA 4245041 c.1809C>G synonymous_variant 0.86 ethambutol
embA 4245056 c.1824C>G synonymous_variant 0.76 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.9 ethambutol
embA 4245074 c.1842G>C synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embA 4245078 p.Trp616Val missense_variant 0.75 ethambutol
embA 4245083 c.1851A>G synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embA 4245089 c.1857G>C synonymous_variant 0.91 ethambutol
embA 4245093 p.Ile621Val missense_variant 0.79 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 0.95 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.94 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.92 ethambutol
embA 4245164 c.1932C>T synonymous_variant 0.91 ethambutol
embA 4245173 c.1941G>C synonymous_variant 0.82 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.77 ethambutol
embA 4245183 c.1951C>T synonymous_variant 0.88 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.88 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.84 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.78 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4245680 c.-834G>A upstream_gene_variant 0.94 ethambutol
embA 4245693 c.2461_2463delATCinsGG frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
embA 4245707 c.2475C>T synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4245710 c.-804G>C upstream_gene_variant 0.83 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.96 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 1.0 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embA 4245770 c.2538C>T synonymous_variant 0.81 ethambutol Not assoc w R - Interim
embA 4245771 p.Asn847Ser missense_variant 0.81 ethambutol Uncertain significance
embA 4245785 c.2553G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245788 c.-726C>G upstream_gene_variant 0.76 ethambutol
embB 4245797 c.-717C>G upstream_gene_variant 1.0 ethambutol
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 0.67 ethambutol Uncertain significance
embA 4246164 c.2932T>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embB 4246184 c.-330A>C upstream_gene_variant 0.85 ethambutol
embB 4246187 c.-327C>G upstream_gene_variant 0.69 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 0.93 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.82 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.82 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.82 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embA 4246227 p.Ile999Val missense_variant 0.82 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embB 4246250 c.-264G>C upstream_gene_variant 0.85 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.89 ethambutol
embB 4246262 c.-252C>T upstream_gene_variant 0.88 ethambutol
embB 4246268 c.-246G>A upstream_gene_variant 0.88 ethambutol
embB 4246271 c.-243G>A upstream_gene_variant 0.88 ethambutol
embA 4246290 p.Leu1020Gly missense_variant 0.8 ethambutol
embA 4246299 p.Ser1023Ala missense_variant 0.8 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.86 ethambutol
embA 4246308 p.Thr1026Asp missense_variant 0.8 ethambutol
embB 4246313 c.-201C>G upstream_gene_variant 0.88 ethambutol
embA 4246338 p.Leu1036Met missense_variant 0.91 ethambutol
embB 4246361 c.-153C>G upstream_gene_variant 0.89 ethambutol
embB 4246373 c.-141T>G upstream_gene_variant 0.83 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.84 ethambutol
embA 4246383 p.Tyr1051His missense_variant 0.83 ethambutol
embB 4246400 c.-114G>C upstream_gene_variant 0.82 ethambutol
embA 4246413 p.His1061Phe missense_variant 0.88 ethambutol
embA 4246419 c.3187C>T synonymous_variant 0.81 ethambutol Not assoc w R - Interim
embB 4246430 c.-84C>T upstream_gene_variant 0.83 ethambutol
embB 4247375 p.Leu288Val missense_variant 0.64 ethambutol
embB 4247380 c.867C>G synonymous_variant 0.73 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.88 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.88 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.9 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.91 ethambutol
embB 4247437 c.924A>C synonymous_variant 0.93 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.9 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.83 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.79 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247544 p.Ser344Thr missense_variant 0.82 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>G synonymous_variant 1.0 ethambutol
embB 4247741 p.Leu410Val missense_variant 0.83 ethambutol
embB 4247746 c.1233C>G synonymous_variant 0.85 ethambutol
embB 4247753 p.Val414Ile missense_variant 0.94 ethambutol Uncertain significance
embB 4247776 c.1263G>C synonymous_variant 0.9 ethambutol
embB 4247779 c.1266C>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 0.91 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.93 ethambutol
embB 4247800 c.1287A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247803 c.1290G>C synonymous_variant 0.93 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.96 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 0.96 ethambutol
embB 4247836 c.1323A>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4247842 c.1329T>G synonymous_variant 0.95 ethambutol
embB 4247851 c.1338C>G synonymous_variant 0.82 ethambutol
embB 4247857 c.1344C>A synonymous_variant 0.9 ethambutol
embB 4247858 c.1345C>T synonymous_variant 0.82 ethambutol
embB 4247866 c.1353G>C synonymous_variant 0.82 ethambutol
embB 4247938 c.1425G>C synonymous_variant 0.95 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.95 ethambutol
embB 4247945 c.1432T>C synonymous_variant 1.0 ethambutol
embB 4247951 p.Ser480Ala missense_variant 1.0 ethambutol
embB 4247974 c.1461C>G synonymous_variant 0.96 ethambutol
embB 4247986 c.1473C>G synonymous_variant 0.92 ethambutol
embB 4248001 c.1488C>T synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 0.84 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.89 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.88 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.86 ethambutol
embB 4248052 c.1539G>T synonymous_variant 0.56 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.88 ethambutol
embB 4248058 c.1545C>T synonymous_variant 0.56 ethambutol Not assoc w R - Interim
embB 4248064 c.1551G>C synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.88 ethambutol
embB 4248076 c.1563G>A synonymous_variant 0.54 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.92 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.41 ethambutol
embB 4248100 c.1587C>T synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embB 4248106 c.1593C>G synonymous_variant 0.35 ethambutol
embB 4248112 c.1599C>A synonymous_variant 0.54 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.55 ethambutol
embB 4248122 c.1609C>T synonymous_variant 0.35 ethambutol
embB 4248127 c.1614G>A synonymous_variant 0.55 ethambutol Not assoc w R - Interim
embB 4248130 c.1617G>C synonymous_variant 0.91 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.86 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.52 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.91 ethambutol
embB 4248149 c.1636_1638delACCinsGG frameshift_variant&missense_variant 0.52 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embB 4248158 c.1645_1647delTGCinsAT frameshift_variant&missense_variant 0.29 ethambutol
embB 4248169 c.1656C>G synonymous_variant 0.85 ethambutol
embB 4248172 c.1659G>C synonymous_variant 0.58 ethambutol
embB 4248175 c.1662G>A synonymous_variant 0.58 ethambutol
embB 4248178 c.1665C>T synonymous_variant 0.59 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.87 ethambutol
embB 4248211 c.1698G>A synonymous_variant 0.86 ethambutol
embB 4248214 c.1701C>A synonymous_variant 0.7 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4248226 c.1713G>C synonymous_variant 0.78 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>T synonymous_variant 1.0 ethambutol
embB 4248307 c.1794G>T synonymous_variant 0.91 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.96 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.95 ethambutol
embB 4248322 c.1809G>T synonymous_variant 0.95 ethambutol
embB 4248337 c.1824G>C synonymous_variant 0.88 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.9 ethambutol
embB 4249276 c.2763A>C synonymous_variant 0.83 ethambutol
embB 4249282 c.2769A>C synonymous_variant 0.86 ethambutol
embB 4249296 p.Ala928Val missense_variant 0.95 ethambutol
embB 4249318 c.2805C>G synonymous_variant 0.88 ethambutol
embB 4249321 c.2808A>C synonymous_variant 0.96 ethambutol
embB 4249322 c.2809_2811delGCAinsTC frameshift_variant&missense_variant 0.96 ethambutol
embB 4249325 p.Lys938Gln missense_variant 0.96 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.88 ethambutol
embB 4249342 c.2829C>G synonymous_variant 0.89 ethambutol
embB 4249343 p.Val944Phe missense_variant 0.8 ethambutol
embB 4249351 c.2838C>G synonymous_variant 0.81 ethambutol
embB 4249360 c.2847G>C synonymous_variant 0.79 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.86 ethambutol
embB 4249387 p.Glu958Asp missense_variant 0.71 ethambutol
embB 4249394 p.Ile961Val missense_variant 0.65 ethambutol
embB 4249400 p.Val963Leu missense_variant 0.56 ethambutol
embB 4249414 c.2901G>A synonymous_variant 0.53 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.83 ethambutol
embB 4249568 p.Ser1019Asn missense_variant 0.83 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.83 ethambutol
embB 4249594 c.3081G>A synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embB 4249598 c.3085_3087delGAAinsCG frameshift_variant&missense_variant 0.43 ethambutol
embB 4249607 p.Thr1032Val missense_variant 0.5 ethambutol
embB 4249624 c.3111C>G synonymous_variant 0.92 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.91 ethambutol
aftB 4267559 c.1278C>G synonymous_variant 0.5 ethambutol
aftB 4267577 p.His420Gln missense_variant 0.75 ethambutol
aftB 4267580 c.1257G>T synonymous_variant 0.75 ethambutol
aftB 4267595 c.1242C>T synonymous_variant 0.89 ethambutol
aftB 4267604 c.1233C>T synonymous_variant 0.92 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.83 ethambutol
aftB 4267631 c.1206C>G synonymous_variant 0.83 ethambutol
aftB 4267634 p.Arg401His missense_variant 0.93 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
aftB 4267655 c.1182C>G synonymous_variant 0.92 ethambutol
aftB 4267667 c.1170A>G synonymous_variant 0.71 ethambutol
aftB 4269018 c.-182G>C upstream_gene_variant 0.55 ethambutol
aftB 4269027 c.-191C>G upstream_gene_variant 1.0 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 1.0 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.73 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.93 ethambutol
ubiA 4269075 c.757_759delATTinsGG frameshift_variant&missense_variant 0.92 ethambutol
ubiA 4269080 p.Met252Leu missense_variant 0.77 ethambutol
ubiA 4269091 p.Phe248Tyr missense_variant 0.67 ethambutol
aftB 4269102 c.-268_-266delAGCinsTCG upstream_gene_variant 0.54 ethambutol
ubiA 4269107 p.Tyr243His missense_variant 0.54 ethambutol
ubiA 4269109 p.Gly242His missense_variant 0.54 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 0.79 ethambutol
aftB 4269132 c.-296G>C upstream_gene_variant 0.77 ethambutol
ubiA 4269141 c.691_693delTTGinsAC frameshift_variant&missense_variant 0.79 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.82 ethambutol Not assoc w R - Interim
ubiA 4269164 p.Leu224Met missense_variant 0.83 ethambutol
ubiA 4269177 c.657G>A synonymous_variant 0.67 ethambutol Not assoc w R - Interim
aftB 4269183 c.-347T>C upstream_gene_variant 0.83 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.75 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.68 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 0.83 ethambutol
ubiA 4269240 c.592_594delCTGinsGC frameshift_variant&missense_variant 0.59 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.76 ethambutol
aftB 4269248 c.-412C>T upstream_gene_variant 0.62 ethambutol
aftB 4269249 c.-413G>A upstream_gene_variant 0.62 ethambutol
ethR 4327396 c.-153A>G upstream_gene_variant 0.93 ethionamide
ethA 4327399 p.Asp25Glu missense_variant 0.8 ethionamide
ethR 4327423 c.-126G>C upstream_gene_variant 0.88 ethionamide
ethR 4327426 c.-123A>G upstream_gene_variant 0.88 ethionamide
ethR 4327435 c.-114T>G upstream_gene_variant 0.8 ethionamide
ethR 4327438 c.-111A>G upstream_gene_variant 0.93 ethionamide
ethA 4327452 p.Val8Leu missense_variant 0.86 ethionamide
ethR 4327453 c.-96A>G upstream_gene_variant 0.93 ethionamide
ethR 4327459 c.-90G>A upstream_gene_variant 0.92 ethionamide
ethR 4327468 c.-81G>A upstream_gene_variant 0.9 ethionamide
ethA 4327674 c.-201C>G upstream_gene_variant 0.91 ethionamide
ethA 4327680 c.-207A>G upstream_gene_variant 0.91 ethionamide
ethA 4327686 c.-213C>G upstream_gene_variant 0.91 ethionamide
ethA 4327689 c.-216G>C upstream_gene_variant 0.91 ethionamide
ethA 4327695 c.-222A>G upstream_gene_variant 0.91 ethionamide
ethR 4327714 c.166_168delATCinsCG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
ethA 4327719 c.-246C>G upstream_gene_variant 1.0 ethionamide
ethA 4327720 c.-247T>G upstream_gene_variant 1.0 ethionamide
ethR 4327744 c.196_198delCCAinsTG frameshift_variant&stop_gained 1.0 ethionamide Uncertain significance
ethR 4327755 p.Glu69Asp missense_variant 1.0 ethionamide