Run ID: ERR158583
Sample name:
Date: 2024-04-15T23:34:03.989672
Number of reads: 1781558
Percentage reads mapped: 25.87
Median coverage: 33.0
Strain: La3;M.canetti;lineage2;lineage4.2;lineage4.3
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage1.1.2 | Indo-Oceanic | RD239 | 0.12 |
lineage4.3 | Euro-American (LAM) | None | 0.08 |
lineage2 | East-Asian | RD105 | 0.18 |
lineage4.2 | Euro-American | None | 0.18 |
lineage4.6.4 | Euro-American | None | 0.23 |
La3 | M.orygis | None | 0.06 |
M.canetti | M.canetti | None | 0.17 |
lineage4.8.2 | Euro-American (mainly T) | RD219 | 0.06 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | katG | c.496_498delGTTinsAC | Assoc w R | High-level resistance |
ethambutol | embB | p.His312Arg | Mutation from literature | |
p.Tyr384Asn | Mutation from literature | |||
p.Thr437Ala | Mutation from literature | |||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | tlyA | c.1dupG | Assoc w R | |
kanamycin | ||||
cycloserine | ||||
ethionamide | ethA | c.1015_1017delATTinsGC | Assoc w R | |
c.751_753delAGCinsGG | Assoc w R | |||
c.478_480delCCGinsGC | Assoc w R | |||
p.Glu39* | Assoc w R | |||
clofazimine | pepQ | c.865_867delCACinsAT | Assoc w R - Interim | |
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.730_732delAACinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
fbiC | c.562_564delTTGinsCT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.751_753delTTGinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.859_861delATCinsGT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.895_897delGAAinsAG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1018_1020delGGCinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1039_1041delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1144_1146delGCCinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1270_1272delCTGinsTC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1591_1593delCTGinsGA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.2344_2346delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiD | c.364_366delACAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
fbiA | c.706_708delGCAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
fbiB | c.1150_1152delTTGinsCA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
ddn | c.316_318delGTGinsAT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
bedaquiline | pepQ | c.865_867delCACinsAT | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV |
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 491512 | c.730_732delAACinsCG | frameshift_variant&missense_variant | 0.93 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 0.91 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
fbiC | 1303492 | c.562_564delTTGinsCT | frameshift_variant&synonymous_variant | 0.82 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303681 | c.751_753delTTGinsCC | frameshift_variant&missense_variant | 0.96 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303789 | c.859_861delATCinsGT | frameshift_variant&missense_variant | 0.96 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303825 | c.895_897delGAAinsAG | frameshift_variant&missense_variant | 0.86 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303948 | c.1018_1020delGGCinsCG | frameshift_variant&missense_variant | 0.7 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303969 | c.1039_1041delGTTinsAC | frameshift_variant&missense_variant | 0.7 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304074 | c.1144_1146delGCCinsTG | frameshift_variant&missense_variant | 0.76 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304200 | c.1270_1272delCTGinsTC | frameshift_variant&missense_variant | 0.94 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304521 | c.1591_1593delCTGinsGA | frameshift_variant&missense_variant | 0.94 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1305274 | c.2344_2346delTCGinsGC | frameshift_variant&missense_variant | 0.73 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
tlyA | 1917939 | c.1dupG | frameshift_variant | 0.86 | capreomycin | Assoc w R | |
katG | 2155614 | c.496_498delGTTinsAC | frameshift_variant&missense_variant | 0.91 | isoniazid | Assoc w R | High-level resistance |
pepQ | 2859552 | c.865_867delCACinsAT | frameshift_variant&synonymous_variant | 0.89 | bedaquiline | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV |
clofazimine | Assoc w R - Interim | ||||||
fbiD | 3339481 | c.364_366delACAinsCG | frameshift_variant&missense_variant | 0.73 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiA | 3641248 | c.706_708delGCAinsAC | frameshift_variant&missense_variant | 0.85 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiB | 3642684 | c.1150_1152delTTGinsCA | frameshift_variant&missense_variant | 0.9 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
ddn | 3987159 | c.316_318delGTGinsAT | frameshift_variant&missense_variant | 0.9 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
embB | 4247448 | p.His312Arg | missense_variant | 0.94 | ethambutol | Mutation from literature | |
embB | 4247663 | p.Tyr384Asn | missense_variant | 0.96 | ethambutol | Mutation from literature | |
embB | 4247822 | p.Thr437Ala | missense_variant | 0.94 | ethambutol | Mutation from literature | |
ethA | 4326457 | c.1015_1017delATTinsGC | frameshift_variant&missense_variant | 0.7 | ethionamide | Assoc w R | |
ethA | 4326721 | c.751_753delAGCinsGG | frameshift_variant&missense_variant | 0.64 | ethionamide | Assoc w R | |
ethA | 4326994 | c.478_480delCCGinsGC | frameshift_variant&missense_variant | 0.73 | ethionamide | Assoc w R | |
ethA | 4327359 | p.Glu39* | stop_gained | 0.72 | ethionamide | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 705 | c.705A>G | synonymous_variant | 0.82 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.86 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.88 | isoniazid | Not assoc w R - Interim |
dnaA | 747 | c.747G>C | synonymous_variant | 0.88 | isoniazid | |
dnaA | 748 | c.748_750delCTCinsTG | frameshift_variant&missense_variant | 0.88 | isoniazid | Uncertain significance |
dnaA | 753 | c.753C>T | synonymous_variant | 0.88 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.88 | isoniazid | |
dnaA | 762 | c.762C>T | synonymous_variant | 0.88 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.93 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
dnaA | 802 | c.802C>T | synonymous_variant | 0.91 | isoniazid | |
dnaA | 805 | c.805_807delTTGinsCC | frameshift_variant&missense_variant | 0.9 | isoniazid | Uncertain significance |
dnaA | 810 | c.810C>G | synonymous_variant | 0.9 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.9 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
dnaA | 837 | c.837A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.95 | isoniazid | |
dnaA | 843 | c.843T>C | synonymous_variant | 0.98 | isoniazid | Not assoc w R - Interim |
dnaA | 849 | c.849A>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 876 | c.876C>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.95 | isoniazid | |
dnaA | 888 | c.888C>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.93 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.96 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 0.96 | isoniazid | |
dnaA | 939 | c.939C>A | synonymous_variant | 0.95 | isoniazid | Not assoc w R - Interim |
dnaA | 945 | c.945G>A | synonymous_variant | 0.94 | isoniazid | |
dnaA | 955 | c.955_957delAGAinsCG | frameshift_variant&synonymous_variant | 0.85 | isoniazid | Uncertain significance |
dnaA | 963 | c.963C>G | synonymous_variant | 0.83 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.83 | isoniazid | |
dnaA | 969 | c.969G>A | synonymous_variant | 0.83 | isoniazid | |
dnaA | 975 | c.975G>C | synonymous_variant | 0.83 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.83 | isoniazid | Not assoc w R - Interim |
dnaA | 987 | c.987C>T | synonymous_variant | 0.83 | isoniazid | |
dnaA | 990 | c.990A>G | synonymous_variant | 0.83 | isoniazid | Not assoc w R - Interim |
dnaA | 993 | c.993A>G | synonymous_variant | 0.83 | isoniazid | |
dnaA | 996 | c.996A>C | synonymous_variant | 0.83 | isoniazid | Not assoc w R - Interim |
dnaA | 999 | c.999C>G | synonymous_variant | 0.85 | isoniazid | |
dnaA | 1003 | c.1003C>T | synonymous_variant | 0.88 | isoniazid | |
dnaA | 1035 | c.1035A>G | synonymous_variant | 0.93 | isoniazid | |
dnaA | 1059 | c.1059C>A | synonymous_variant | 0.92 | isoniazid | |
dnaA | 1074 | c.1074C>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1083 | c.1083C>T | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1122 | c.1122C>T | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1125 | c.1125G>A | synonymous_variant | 0.96 | isoniazid | Not assoc w R - Interim |
dnaA | 1143 | c.1143G>A | synonymous_variant | 0.88 | isoniazid | Not assoc w R - Interim |
dnaA | 1149 | c.1149C>T | synonymous_variant | 0.85 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.85 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.85 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.88 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.88 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.89 | isoniazid | Not assoc w R - Interim |
dnaA | 1179 | c.1179G>C | synonymous_variant | 0.94 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.92 | isoniazid | |
dnaA | 1194 | c.1194G>C | synonymous_variant | 0.92 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.92 | isoniazid | |
dnaA | 1200 | c.1200C>T | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1206 | c.1206G>C | synonymous_variant | 0.91 | isoniazid | Not assoc w R - Interim |
dnaA | 1220 | p.Asn407Thr | missense_variant | 0.91 | isoniazid | |
dnaA | 1222 | p.Thr408Ala | missense_variant | 0.91 | isoniazid | Uncertain significance |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.93 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.92 | isoniazid | |
dnaA | 1281 | c.1281C>G | synonymous_variant | 0.9 | isoniazid | |
dnaA | 1293 | c.1293T>G | synonymous_variant | 0.9 | isoniazid | |
dnaA | 1299 | c.1299G>A | synonymous_variant | 0.9 | isoniazid | |
dnaA | 1302 | c.1302C>G | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1311 | c.1311C>G | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1315 | c.1315_1317delGCAinsTG | frameshift_variant&stop_gained | 0.83 | isoniazid | Uncertain significance |
dnaA | 1332 | c.1332A>C | synonymous_variant | 0.76 | isoniazid | Not assoc w R - Interim |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1350 | c.1350G>C | synonymous_variant | 0.79 | isoniazid | Not assoc w R - Interim |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.76 | isoniazid | |
dnaA | 1356 | c.1356T>G | synonymous_variant | 0.77 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.82 | isoniazid | |
dnaA | 1374 | c.1374G>T | synonymous_variant | 0.82 | isoniazid | Not assoc w R - Interim |
dnaA | 1375 | c.1375T>C | synonymous_variant | 0.82 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.86 | isoniazid | |
dnaA | 1389 | c.1389C>T | synonymous_variant | 0.87 | isoniazid | Not assoc w R - Interim |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.88 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.93 | isoniazid | |
dnaA | 1441 | c.1441C>T | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1458 | c.1458G>A | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1464 | c.1464T>C | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1467 | c.1467G>A | synonymous_variant | 0.92 | isoniazid | Not assoc w R - Interim |
dnaA | 1473 | c.1473T>C | synonymous_variant | 0.92 | isoniazid | Not assoc w R - Interim |
dnaA | 1488 | c.1488A>G | synonymous_variant | 0.88 | isoniazid | |
dnaA | 1494 | c.1494C>G | synonymous_variant | 0.82 | isoniazid | |
dnaA | 1497 | c.1497T>A | synonymous_variant | 0.81 | isoniazid | |
dnaA | 1498 | c.1498_1500delCGCinsAG | frameshift_variant&missense_variant | 0.81 | isoniazid | Uncertain significance |
gyrB | 5229 | c.-11G>A | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5230 | c.-10T>C | upstream_gene_variant | 0.62 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrB | 5238 | c.-2T>C | upstream_gene_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5254 | c.15A>G | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5284 | c.45G>A | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5287 | c.48T>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5293 | c.54C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5302 | c.63A>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5305 | c.66G>A | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5308 | c.69G>A | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5341 | c.102T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5359 | c.120C>T | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5363 | c.124_126delTTAinsCG | frameshift_variant&missense_variant | 0.87 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 5377 | c.138T>C | synonymous_variant | 0.82 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5422 | c.183T>C | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5425 | c.186A>G | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5426 | p.Thr63Ala | missense_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5431 | c.192A>C | synonymous_variant | 0.79 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5434 | c.195G>A | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5436 | p.Asn66Ser | missense_variant | 0.82 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrB | 5440 | c.201A>G | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5449 | c.210T>C | synonymous_variant | 0.84 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5455 | c.216T>C | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5470 | c.231C>G | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5485 | c.246C>T | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5488 | c.249C>A | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5491 | c.252T>C | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5500 | c.261C>A | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5502 | p.Thr88Met | missense_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5527 | c.288C>G | synonymous_variant | 0.84 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5542 | c.303A>C | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5545 | c.306A>G | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5548 | c.309A>G | synonymous_variant | 0.76 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5551 | c.312T>C | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5560 | c.321C>G | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5569 | c.330C>T | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5572 | c.333G>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5710 | c.471C>A | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5722 | c.483G>C | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5731 | c.492C>T | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5740 | c.501G>C | synonymous_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5743 | c.504G>C | synonymous_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5744 | c.505_507delTCAinsAG | frameshift_variant&missense_variant | 0.86 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 5767 | c.528C>T | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5771 | p.Ala178Asn | missense_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5779 | c.540C>T | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5782 | c.543A>G | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5788 | c.549G>C | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5791 | c.552A>G | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5812 | c.573C>A | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5815 | c.576C>A | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5819 | c.580C>T | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5836 | c.597C>T | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5851 | c.612G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5860 | c.621C>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5869 | c.630C>T | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5870 | p.Glu211Gln | missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5873 | c.634A>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5884 | c.645A>G | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5902 | c.663A>G | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5926 | c.687G>C | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5929 | c.690G>A | synonymous_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6049 | c.810G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6052 | c.813T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6055 | c.816T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6067 | c.828G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6073 | c.834T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6079 | c.840C>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6085 | c.846C>A | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6086 | p.Thr283Pro | missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6091 | c.852G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6097 | c.858G>A | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6121 | c.882C>T | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6145 | c.906C>T | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6178 | c.939C>T | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6181 | c.942C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6196 | c.957C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6247 | c.1008G>A | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6259 | p.Asp340Glu | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6313 | c.-989C>T | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6358 | c.1119C>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6400 | c.-902C>G | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6415 | c.-887G>C | upstream_gene_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6421 | c.-881C>T | upstream_gene_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6427 | c.-875T>C | upstream_gene_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6430 | c.-872A>G | upstream_gene_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6674 | c.1435_1437delCTTinsTG | frameshift_variant&missense_variant | 0.96 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 6680 | c.1441C>T | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 0.83 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6764 | c.-538C>T | upstream_gene_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6769 | c.-533C>T | upstream_gene_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.76 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6787 | c.-515G>A | upstream_gene_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6798 | p.Gly520Ala | missense_variant | 0.71 | levofloxacin | Not assoc w R |
moxifloxacin | Uncertain significance | |||||
gyrB | 6801 | p.Lys521Arg | missense_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6808 | c.1569C>T | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6826 | c.-476G>C | upstream_gene_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.85 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6866 | c.-436C>T | upstream_gene_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6872 | c.-430T>C | upstream_gene_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6886 | c.-416C>T | upstream_gene_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6889 | c.-413G>C | upstream_gene_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6898 | c.-404G>T | upstream_gene_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7018 | c.-284G>A | upstream_gene_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7024 | c.-278G>C | upstream_gene_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7030 | c.-272C>A | upstream_gene_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7060 | c.1821T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7081 | c.-221T>C | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7093 | c.1854T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7120 | c.-182T>C | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7123 | c.-179C>G | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>G | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7151 | c.1912C>T | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>A | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7207 | c.-95C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7210 | c.-92C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7213 | c.-89G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7219 | c.-83C>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7231 | c.-71C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7246 | c.2007T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7252 | c.-50G>C | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7340 | p.Asp13Glu | missense_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7349 | c.48A>G | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7355 | c.54T>C | synonymous_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.85 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>A | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7619 | c.318C>T | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7652 | c.351C>G | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7703 | c.402G>A | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7715 | c.414G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7766 | c.465C>T | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7769 | c.468C>T | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7832 | c.531G>T | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7838 | c.537C>T | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7850 | c.549C>G | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7886 | c.585T>C | synonymous_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7889 | c.588G>A | synonymous_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7919 | p.Glu206Asp | missense_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7923 | p.His208Tyr | missense_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7940 | c.639G>A | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7941 | p.Glu214Thr | missense_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7946 | c.645C>G | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7958 | c.657C>G | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7963 | p.Gly221Glu | missense_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7970 | c.669T>C | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7973 | c.672A>G | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7979 | c.678G>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7988 | c.687G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7997 | c.696A>G | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8000 | c.699G>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8020 | p.Thr240Ile | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8024 | c.723T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8027 | c.726T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8030 | c.729C>A | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8036 | c.735A>G | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8039 | c.738T>C | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8042 | c.741C>T | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8048 | c.747C>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8054 | c.753T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8057 | c.756A>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8078 | c.777A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8084 | c.783G>A | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8105 | c.804G>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8174 | c.873C>G | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8195 | c.894C>T | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8199 | p.Ser300Ala | missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8217 | p.Ser306Gly | missense_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8225 | p.Asp308Glu | missense_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8235 | c.934_936delTTAinsGG | frameshift_variant&missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8258 | c.957G>A | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8282 | c.981G>A | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.96 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8315 | c.1014G>A | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8318 | c.1017C>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | c.1039_1041delGCGinsTC | frameshift_variant&missense_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8393 | c.1092T>C | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.86 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8402 | p.Asp367Glu | missense_variant | 0.85 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8421 | c.1120_1122delGTGinsAC | frameshift_variant&missense_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8433 | p.Thr378Arg | missense_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8447 | c.1146C>A | synonymous_variant | 0.84 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8450 | c.1149G>A | synonymous_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.87 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>G | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8510 | c.1209G>A | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8513 | c.1212C>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>A | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8561 | c.1260A>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8562 | c.1261C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8571 | c.1270C>T | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8609 | c.1308G>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8627 | c.1326C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8633 | c.1332C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8645 | c.1344C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8655 | p.Ile452Val | missense_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8666 | c.1365G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8694 | c.1393C>T | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8723 | c.1422G>A | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8732 | c.1431G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8752 | p.Ala484Gly | missense_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.94 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8783 | c.1482G>T | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8795 | c.1494C>T | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8796 | p.Ile499Val | missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8813 | c.1512C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8825 | c.1524G>A | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8876 | c.1575C>T | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8924 | c.1623C>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>A | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8945 | c.1644G>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8981 | c.1680G>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.97 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9003 | c.1702C>T | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9017 | c.1716C>T | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.99 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9065 | c.1764C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9101 | c.1800A>G | synonymous_variant | 0.86 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9197 | c.1896G>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9218 | c.1917C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9236 | c.1935G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.98 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9257 | c.1956C>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9315 | c.2014C>T | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9323 | c.2022C>T | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9341 | c.2040C>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9371 | c.2070G>A | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9401 | c.2100G>A | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9413 | c.2112G>A | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9419 | c.2118T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9420 | p.Ile707Ala | missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9449 | c.2148C>G | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9452 | c.2151G>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9476 | c.2175G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9479 | c.2178G>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9485 | c.2184A>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9488 | c.2187G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9491 | c.2190C>T | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9494 | c.2193T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9497 | c.2196G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9503 | c.2202T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9518 | c.2217A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9527 | c.2226A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9542 | c.2241T>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9545 | c.2244A>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9551 | c.2250G>A | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9557 | c.2256G>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9560 | c.2259C>G | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9566 | c.2265C>T | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9585 | c.2284T>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9590 | c.2289T>G | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9593 | c.2292G>A | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9602 | c.2301T>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9604 | p.Val768Ala | missense_variant | 0.94 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9626 | c.2325T>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9629 | c.2328C>A | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9630 | p.Val777Ile | missense_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9635 | c.2334T>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9644 | c.2343T>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9650 | c.2349G>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9656 | c.2355C>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9659 | c.2358C>G | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9668 | c.2367C>A | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9689 | c.2388G>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9704 | c.2403T>C | synonymous_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9707 | c.2406G>C | synonymous_variant | 0.85 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9716 | c.2415T>C | synonymous_variant | 0.81 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9722 | c.2421C>T | synonymous_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9734 | c.2433A>T | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9749 | c.2448G>A | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13879 | c.-321T>G | upstream_gene_variant | 0.82 | isoniazid | |
Rv0010c | 13891 | c.-333G>C | upstream_gene_variant | 0.9 | isoniazid | |
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.94 | isoniazid | |
Rv0010c | 13906 | c.-348C>T | upstream_gene_variant | 0.91 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 0.91 | isoniazid | |
fgd1 | 490781 | c.-2T>G | upstream_gene_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490782 | c.-1G>A | upstream_gene_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490794 | c.12G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.93 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490809 | c.27A>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490818 | c.36C>T | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490830 | c.48A>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490853 | p.Ala24Gly | missense_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490863 | c.81C>A | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490869 | c.87C>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490921 | p.Gln47Lys | missense_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490929 | c.147C>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490935 | c.153C>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490945 | c.163C>T | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490962 | c.180T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490971 | c.189A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490984 | p.Leu68Val | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490995 | c.213C>T | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>G | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491067 | c.285C>T | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491077 | p.Asn99Asp | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491085 | c.303T>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491091 | c.309T>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491094 | c.312C>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491142 | c.360C>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491154 | p.Glu124Asp | missense_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491163 | c.381G>A | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491166 | c.384G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491196 | c.414A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491226 | c.444C>G | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491265 | c.483G>C | synonymous_variant | 0.89 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.83 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.73 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491298 | c.516C>G | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491316 | c.534C>T | synonymous_variant | 0.76 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491331 | c.549G>A | synonymous_variant | 0.76 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.72 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491453 | p.Gly224Asp | missense_variant | 0.7 | clofazimine | Uncertain significance |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
fgd1 | 491478 | c.696G>A | synonymous_variant | 0.86 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491487 | c.705C>T | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491496 | c.714C>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491499 | c.717G>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491508 | c.726A>T | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491523 | c.741G>A | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491553 | c.771G>A | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491604 | c.822G>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491628 | c.846G>A | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491664 | c.882C>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575506 | c.159C>T | synonymous_variant | 0.8 | ethionamide | |
isoniazid | ||||||
mshA | 575512 | c.165A>G | synonymous_variant | 0.77 | ethionamide | |
isoniazid | ||||||
mshA | 575521 | c.174A>C | synonymous_variant | 0.86 | ethionamide | |
isoniazid | ||||||
mshA | 575536 | c.189T>C | synonymous_variant | 0.9 | ethionamide | |
isoniazid | ||||||
mshA | 575539 | c.192C>T | synonymous_variant | 0.9 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575545 | c.198C>T | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575548 | c.201C>A | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575561 | p.Met72Val | missense_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575572 | c.225T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575596 | c.249C>T | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575629 | c.282A>T | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575633 | c.286_288delGCAinsAG | frameshift_variant&missense_variant | 0.94 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 575652 | p.Arg102Gln | missense_variant | 0.9 | ethionamide | |
isoniazid | ||||||
mshA | 575662 | c.315C>G | synonymous_variant | 0.89 | ethionamide | |
isoniazid | ||||||
mshA | 575665 | c.318G>C | synonymous_variant | 0.89 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575671 | c.324G>C | synonymous_variant | 0.89 | ethionamide | |
isoniazid | ||||||
mshA | 575686 | c.339G>A | synonymous_variant | 0.9 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575689 | c.342G>C | synonymous_variant | 0.89 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575732 | c.385_387delCTTinsTG | frameshift_variant&missense_variant | 0.95 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575770 | c.423G>C | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575772 | p.Val142Ala | missense_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575785 | c.438T>C | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.88 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.91 | ethionamide | |
isoniazid | ||||||
mshA | 575842 | c.495G>C | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575848 | c.501C>T | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575851 | c.504C>T | synonymous_variant | 0.94 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575878 | c.531A>T | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575890 | c.543C>G | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575892 | p.Ala182Val | missense_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575902 | c.555C>T | synonymous_variant | 0.94 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575916 | p.Asp190Ala | missense_variant | 0.86 | ethionamide | |
isoniazid | ||||||
mshA | 575920 | c.573C>T | synonymous_variant | 0.84 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575925 | p.Gly193Ala | missense_variant | 0.74 | ethionamide | |
isoniazid | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.92 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619597 | c.-294G>C | upstream_gene_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619624 | c.-267C>T | upstream_gene_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619648 | c.-243C>G | upstream_gene_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619654 | c.-237A>C | upstream_gene_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619655 | c.-236A>G | upstream_gene_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619669 | c.-222G>C | upstream_gene_variant | 0.92 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>G | upstream_gene_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619681 | c.-210G>A | upstream_gene_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619697 | c.-194A>C | upstream_gene_variant | 0.89 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619708 | c.-183G>C | upstream_gene_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619713 | c.-178_-177delCGinsTC | upstream_gene_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619720 | c.-171C>T | upstream_gene_variant | 0.87 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619727 | c.-164_-162delACGinsGC | upstream_gene_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619734 | c.-157_-156delCGinsATACCCCC | upstream_gene_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619744 | c.-147A>G | upstream_gene_variant | 0.86 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619766 | c.-125A>G | upstream_gene_variant | 0.85 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619771 | c.-120C>G | upstream_gene_variant | 0.75 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620173 | p.Val95Ile | missense_variant | 0.73 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620184 | c.294C>G | synonymous_variant | 0.81 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620197 | p.Gln103Met | missense_variant | 0.8 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620214 | c.324C>A | synonymous_variant | 0.76 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620245 | p.Leu119Met | missense_variant | 0.82 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620256 | c.366C>G | synonymous_variant | 0.84 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620257 | p.Ile123Val | missense_variant | 0.84 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620271 | c.381C>G | synonymous_variant | 0.86 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.81 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.81 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620290 | p.Tyr134Asn | missense_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.85 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620314 | c.424C>T | synonymous_variant | 0.95 | capreomycin | |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620325 | c.435G>T | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620337 | c.447C>G | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620358 | c.468C>G | synonymous_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620397 | c.507C>G | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620404 | c.514C>T | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.92 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620418 | c.528G>C | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620439 | c.549T>G | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620460 | c.570T>C | synonymous_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620461 | p.Val191Ile | missense_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620482 | p.Val198Leu | missense_variant | 0.69 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620487 | c.597C>G | synonymous_variant | 0.78 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620490 | c.600A>C | synonymous_variant | 0.78 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620545 | p.Leu219Phe | missense_variant | 0.69 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620571 | c.681A>G | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620604 | c.714C>G | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620607 | c.717T>G | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620613 | c.723C>T | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620619 | c.729G>A | synonymous_variant | 0.99 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620622 | c.732G>C | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620631 | c.741T>G | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>T | synonymous_variant | 0.97 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620685 | c.795G>A | synonymous_variant | 0.96 | capreomycin | Not assoc w R - Interim |
amikacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620710 | c.820_822delGTGinsAC | frameshift_variant&missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620727 | c.837G>T | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620730 | c.840C>T | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620742 | c.852G>C | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>C | synonymous_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620760 | c.870C>G | synonymous_variant | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620766 | c.876C>G | synonymous_variant | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620773 | p.Ile295Val | missense_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620783 | p.Ala298Val | missense_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620787 | c.897C>G | synonymous_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620808 | c.918T>C | synonymous_variant | 0.95 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620829 | c.939G>T | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620838 | c.948C>T | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620839 | c.949C>T | synonymous_variant | 0.92 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620847 | c.957G>C | synonymous_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620853 | c.963G>T | synonymous_variant | 0.79 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656031 | c.1440A>G | synonymous_variant | 0.8 | ethionamide | |
Rv0565c | 656052 | c.1419A>G | synonymous_variant | 0.77 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656067 | c.1404C>T | synonymous_variant | 0.86 | ethionamide | |
Rv0565c | 656073 | p.Leu466Phe | missense_variant | 0.87 | ethionamide | |
Rv0565c | 656076 | c.1395C>T | synonymous_variant | 0.88 | ethionamide | |
Rv0565c | 656085 | c.1386A>G | synonymous_variant | 0.89 | ethionamide | |
Rv0565c | 656088 | c.1383A>G | synonymous_variant | 0.89 | ethionamide | |
Rv0565c | 656103 | c.1368G>A | synonymous_variant | 0.88 | ethionamide | |
Rv0565c | 656112 | c.1359C>A | synonymous_variant | 0.9 | ethionamide | |
Rv0565c | 656116 | p.Lys452Arg | missense_variant | 0.89 | ethionamide | |
Rv0565c | 656129 | p.Tyr448His | missense_variant | 0.91 | ethionamide | |
Rv0565c | 656131 | p.Pro447Leu | missense_variant | 0.9 | ethionamide | |
Rv0565c | 656135 | p.Ala446Ser | missense_variant | 0.95 | ethionamide | |
Rv0565c | 656136 | c.1335G>C | synonymous_variant | 0.95 | ethionamide | |
Rv0565c | 656140 | p.Lys444Leu | missense_variant | 0.95 | ethionamide | |
Rv0565c | 656169 | c.1302G>C | synonymous_variant | 0.9 | ethionamide | |
Rv0565c | 656262 | c.1209C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656277 | c.1194C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656282 | c.1189C>T | synonymous_variant | 0.97 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656295 | c.1176C>T | synonymous_variant | 0.97 | ethionamide | |
Rv0565c | 656301 | c.1170C>T | synonymous_variant | 0.97 | ethionamide | |
Rv0565c | 656304 | c.1167T>C | synonymous_variant | 0.97 | ethionamide | |
Rv0565c | 656358 | c.1113T>C | synonymous_variant | 0.93 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656364 | c.1107T>C | synonymous_variant | 0.91 | ethionamide | |
Rv0565c | 656876 | p.Leu199Met | missense_variant | 0.59 | ethionamide | |
Rv0565c | 656880 | c.591C>G | synonymous_variant | 0.63 | ethionamide | |
Rv0565c | 656889 | c.582A>G | synonymous_variant | 0.68 | ethionamide | |
Rv0565c | 656895 | c.576G>C | synonymous_variant | 0.71 | ethionamide | |
Rv0565c | 656922 | c.547_549delATCinsGG | frameshift_variant&missense_variant | 0.68 | ethionamide | Uncertain significance |
Rv0565c | 656936 | p.Thr179Ala | missense_variant | 0.75 | ethionamide | |
Rv0565c | 656964 | c.507C>G | synonymous_variant | 0.8 | ethionamide | |
Rv0565c | 656973 | c.498A>G | synonymous_variant | 0.81 | ethionamide | |
Rv0565c | 657023 | p.Glu150Gln | missense_variant | 0.75 | ethionamide | |
Rv0565c | 657027 | c.444T>C | synonymous_variant | 0.71 | ethionamide | |
Rv0565c | 657066 | c.405C>T | synonymous_variant | 0.67 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657070 | p.Tyr134Cys | missense_variant | 0.67 | ethionamide | |
Rv0565c | 657072 | p.His133Gln | missense_variant | 0.67 | ethionamide | |
Rv0565c | 657088 | p.Asn128Gly | missense_variant | 0.57 | ethionamide | |
Rv0565c | 657171 | c.300T>C | synonymous_variant | 0.87 | ethionamide | |
Rv0565c | 657192 | p.Met93Thr | missense_variant | 0.93 | ethionamide | |
Rv0565c | 657196 | p.Asp92Thr | missense_variant | 0.93 | ethionamide | |
Rv0565c | 657201 | c.270C>G | synonymous_variant | 0.91 | ethionamide | |
Rv0565c | 657207 | c.264G>A | synonymous_variant | 0.92 | ethionamide | |
Rv0565c | 657219 | p.Ala84Glu | missense_variant | 0.92 | ethionamide | |
Rv0565c | 657233 | p.Ile80Val | missense_variant | 0.92 | ethionamide | |
Rv0565c | 657240 | c.229_231delGAAinsAG | frameshift_variant&synonymous_variant | 0.92 | ethionamide | Uncertain significance |
Rv0565c | 657243 | c.228C>A | synonymous_variant | 0.92 | ethionamide | |
Rv0565c | 657267 | c.202_204delTCGinsAGC | synonymous_variant | 0.91 | ethionamide | |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.98 | ethionamide | |
Rv0565c | 657303 | c.168C>G | synonymous_variant | 0.96 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.91 | ethionamide | |
Rv0565c | 657340 | p.Ala44Glu | missense_variant | 0.69 | ethionamide | |
Rv0565c | 657342 | c.129T>C | synonymous_variant | 0.71 | ethionamide | |
Rv0565c | 657347 | c.124A>C | synonymous_variant | 0.67 | ethionamide | |
Rv0565c | 657348 | c.123A>G | synonymous_variant | 0.67 | ethionamide | |
Rv0565c | 657560 | c.-90G>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657563 | c.-93T>C | upstream_gene_variant | 0.92 | ethionamide | |
Rv0565c | 657571 | c.-101T>C | upstream_gene_variant | 0.94 | ethionamide | |
Rv0565c | 657572 | c.-102A>G | upstream_gene_variant | 0.94 | ethionamide | |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 0.96 | ethionamide | |
Rv0565c | 657587 | c.-117C>T | upstream_gene_variant | 0.94 | ethionamide | |
Rv0565c | 657590 | c.-120G>C | upstream_gene_variant | 0.95 | ethionamide | |
Rv0565c | 657602 | c.-132C>G | upstream_gene_variant | 0.94 | ethionamide | |
Rv0565c | 657629 | c.-159G>A | upstream_gene_variant | 0.96 | ethionamide | |
Rv0565c | 657644 | c.-174G>C | upstream_gene_variant | 0.97 | ethionamide | |
Rv0565c | 657647 | c.-179_-177delGTCinsAT | upstream_gene_variant | 0.94 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.97 | ethionamide | |
Rv0565c | 657678 | c.-208A>C | upstream_gene_variant | 0.97 | ethionamide | |
Rv0565c | 657686 | c.-216C>A | upstream_gene_variant | 0.95 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.96 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.96 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.93 | ethionamide | |
hadA | 731687 | c.-243G>C | upstream_gene_variant | 0.95 | isoniazid | |
hadA | 731689 | c.-241A>G | upstream_gene_variant | 0.95 | isoniazid | |
hadA | 731693 | c.-237_-236insGTTTGACACCAGAT | upstream_gene_variant | 0.95 | isoniazid | |
hadA | 731696 | c.-233_-232delTT | upstream_gene_variant | 0.95 | isoniazid | |
hadA | 731710 | c.-220A>T | upstream_gene_variant | 0.97 | isoniazid | |
hadA | 731711 | c.-219T>C | upstream_gene_variant | 0.94 | isoniazid | |
hadA | 731738 | c.-192G>T | upstream_gene_variant | 0.95 | isoniazid | |
hadA | 731753 | c.-177A>G | upstream_gene_variant | 0.93 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.91 | isoniazid | |
hadA | 731795 | c.-135C>T | upstream_gene_variant | 0.92 | isoniazid | |
hadA | 731816 | c.-114G>C | upstream_gene_variant | 0.93 | isoniazid | |
hadA | 731837 | c.-93C>T | upstream_gene_variant | 0.87 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.9 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 0.86 | isoniazid | |
hadA | 731858 | c.-72G>A | upstream_gene_variant | 0.87 | isoniazid | |
hadA | 732214 | c.285A>G | synonymous_variant | 0.9 | isoniazid | Not assoc w R - Interim |
hadA | 732223 | c.294G>T | synonymous_variant | 0.86 | isoniazid | |
hadA | 732226 | c.297G>C | synonymous_variant | 0.87 | isoniazid | |
hadA | 732229 | c.300C>T | synonymous_variant | 0.88 | isoniazid | |
hadA | 732238 | c.309G>C | synonymous_variant | 0.92 | isoniazid | |
hadA | 732247 | c.318C>T | synonymous_variant | 0.94 | isoniazid | |
hadA | 732250 | c.321C>G | synonymous_variant | 0.94 | isoniazid | |
hadA | 732263 | p.Val112Met | missense_variant | 0.94 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.91 | isoniazid | |
hadA | 732319 | c.390G>A | synonymous_variant | 0.94 | isoniazid | |
hadA | 732322 | p.Glu131Asp | missense_variant | 0.94 | isoniazid | |
hadA | 732329 | c.400_402delCTCinsAT | frameshift_variant&missense_variant | 0.94 | isoniazid | Uncertain significance |
hadA | 732346 | c.417T>C | synonymous_variant | 0.94 | isoniazid | |
hadA | 732361 | c.432C>T | synonymous_variant | 0.94 | isoniazid | |
hadA | 732376 | c.447T>C | synonymous_variant | 0.92 | isoniazid | |
hadA | 732378 | c.449_450insGGA | disruptive_inframe_insertion | 0.91 | isoniazid | |
hadA | 732381 | p.Glu151Val | missense_variant | 0.94 | isoniazid | |
hadA | 732391 | c.462T>A | synonymous_variant | 0.94 | isoniazid | |
nusG | 734075 | c.-179T>G | upstream_gene_variant | 0.91 | rifampicin | |
nusG | 734090 | c.-164G>A | upstream_gene_variant | 0.92 | rifampicin | |
nusG | 734093 | c.-161A>G | upstream_gene_variant | 0.92 | rifampicin | |
nusG | 734102 | c.-152G>T | upstream_gene_variant | 0.96 | rifampicin | |
nusG | 734110 | c.-144_-143delAAinsGG | upstream_gene_variant | 0.96 | rifampicin | |
nusG | 734118 | c.-136_-134delCTTinsAC | upstream_gene_variant | 0.96 | rifampicin | |
nusG | 734135 | c.-119G>A | upstream_gene_variant | 0.96 | rifampicin | |
nusG | 734143 | c.-111C>T | upstream_gene_variant | 0.94 | rifampicin | |
nusG | 734150 | c.-104G>T | upstream_gene_variant | 0.91 | rifampicin | |
nusG | 734337 | c.84G>C | synonymous_variant | 0.67 | rifampicin | |
nusG | 734352 | c.99T>C | synonymous_variant | 0.83 | rifampicin | |
nusG | 734361 | c.108C>T | synonymous_variant | 0.86 | rifampicin | |
nusG | 734370 | c.117A>G | synonymous_variant | 0.88 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.9 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.96 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.96 | rifampicin | |
nusG | 734424 | c.171G>T | synonymous_variant | 0.96 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.99 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
nusG | 734481 | c.228C>T | synonymous_variant | 0.99 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.94 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.96 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.96 | rifampicin | |
nusG | 734616 | c.363C>A | synonymous_variant | 0.94 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.95 | rifampicin | |
nusG | 734631 | c.378G>A | synonymous_variant | 0.96 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 0.97 | rifampicin | |
nusG | 734643 | c.390G>C | synonymous_variant | 0.95 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 0.94 | rifampicin | |
nusG | 734661 | c.408A>C | synonymous_variant | 0.94 | rifampicin | |
nusG | 734664 | c.411T>G | synonymous_variant | 0.92 | rifampicin | |
nusG | 734670 | c.417G>A | synonymous_variant | 0.92 | rifampicin | |
nusG | 734673 | c.420A>G | synonymous_variant | 0.91 | rifampicin | |
nusG | 734680 | p.Ala143Ser | missense_variant | 0.9 | rifampicin | |
nusG | 734703 | c.450T>C | synonymous_variant | 0.87 | rifampicin | |
nusG | 734709 | c.456T>G | synonymous_variant | 0.88 | rifampicin | |
nusG | 734712 | c.459G>C | synonymous_variant | 0.87 | rifampicin | |
nusG | 734718 | c.465G>A | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
nusG | 734719 | p.Ser156Ala | missense_variant | 0.85 | rifampicin | |
nusG | 734722 | p.Thr157Ala | missense_variant | 0.85 | rifampicin | |
nusG | 734726 | p.Arg158Lys | missense_variant | 0.87 | rifampicin | |
nusG | 734733 | c.480T>A | synonymous_variant | 0.87 | rifampicin | |
nusG | 734736 | c.483C>G | synonymous_variant | 0.89 | rifampicin | |
nusG | 734754 | c.501G>C | synonymous_variant | 0.92 | rifampicin | |
nusG | 734757 | c.504T>C | synonymous_variant | 0.92 | rifampicin | |
nusG | 734762 | p.Ala170Val | missense_variant | 0.93 | rifampicin | |
nusG | 734769 | c.516G>A | synonymous_variant | 0.94 | rifampicin | |
nusG | 734781 | c.528A>G | synonymous_variant | 0.93 | rifampicin | |
nusG | 734784 | c.531G>A | synonymous_variant | 0.93 | rifampicin | |
nusG | 734790 | c.537G>C | synonymous_variant | 0.95 | rifampicin | |
nusG | 734793 | c.540C>T | synonymous_variant | 0.95 | rifampicin | |
nusG | 734826 | c.573A>C | synonymous_variant | 0.96 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.94 | rifampicin | |
nusG | 734865 | c.612G>C | synonymous_variant | 0.92 | rifampicin | |
nusG | 734874 | c.621G>A | synonymous_variant | 0.95 | rifampicin | |
nusG | 734880 | c.627C>T | synonymous_variant | 0.94 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 0.93 | rifampicin | |
nusG | 734913 | c.660C>G | synonymous_variant | 0.86 | rifampicin | |
nusG | 734928 | c.675A>G | synonymous_variant | 0.63 | rifampicin | |
rpoB | 759583 | c.-224T>G | upstream_gene_variant | 0.9 | rifampicin | |
rpoB | 759587 | c.-220T>A | upstream_gene_variant | 0.9 | rifampicin | |
rpoB | 759606 | c.-201T>C | upstream_gene_variant | 0.94 | rifampicin | |
rpoB | 759635 | c.-172C>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 759644 | c.-163T>A | upstream_gene_variant | 0.98 | rifampicin | |
rpoB | 759647 | c.-160T>C | upstream_gene_variant | 0.98 | rifampicin | Uncertain significance |
rpoB | 759661 | c.-146G>C | upstream_gene_variant | 0.99 | rifampicin | |
rpoB | 759670 | c.-137C>T | upstream_gene_variant | 0.97 | rifampicin | Uncertain significance |
rpoB | 759671 | c.-136G>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 759675 | c.-132T>C | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 759676 | c.-131A>G | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 759701 | c.-106A>T | upstream_gene_variant | 0.94 | rifampicin | |
rpoB | 759715 | c.-92_-91delGAinsT | upstream_gene_variant | 0.89 | rifampicin | |
rpoB | 759725 | c.-82A>C | upstream_gene_variant | 0.88 | rifampicin | |
rpoB | 759732 | c.-75_-74insT | upstream_gene_variant | 0.84 | rifampicin | |
rpoB | 759835 | p.Ala10Asp | missense_variant | 0.93 | rifampicin | |
rpoB | 759845 | c.39T>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 759846 | p.Ser14Ala | missense_variant | 0.93 | rifampicin | |
rpoB | 759850 | p.Pro15Gln | missense_variant | 0.88 | rifampicin | |
rpoB | 759869 | c.63C>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 759872 | c.66G>A | synonymous_variant | 0.94 | rifampicin | |
rpoB | 759875 | c.69T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 759877 | p.Asn24Ser | missense_variant | 0.94 | rifampicin | |
rpoB | 759884 | c.78A>G | synonymous_variant | 0.92 | rifampicin | |
rpoB | 759896 | c.90A>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 759899 | c.93C>T | synonymous_variant | 0.95 | rifampicin | |
rpoB | 759905 | c.99C>T | synonymous_variant | 0.96 | rifampicin | |
rpoB | 759914 | c.108T>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 759920 | c.114G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 759929 | c.123A>G | synonymous_variant | 0.94 | rifampicin | |
rpoB | 759932 | c.126T>G | synonymous_variant | 0.94 | rifampicin | |
rpoB | 759944 | c.138A>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 759945 | c.139_141delCTCinsTG | frameshift_variant&missense_variant | 0.93 | rifampicin | |
rpoB | 759956 | c.150C>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 759965 | c.159T>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 759989 | c.183G>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 759991 | p.Pro62Gln | missense_variant | 0.96 | rifampicin | |
rpoB | 760059 | p.Tyr85Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 760067 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760070 | c.264T>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760106 | c.300G>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760118 | c.312T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.97 | rifampicin | Uncertain significance |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760172 | c.366G>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760193 | c.387C>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760202 | c.396G>A | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760256 | c.450C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760343 | c.537G>C | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760409 | c.603C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760415 | c.609C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760445 | c.639C>T | synonymous_variant | 0.95 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 760508 | c.702G>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 760511 | c.705G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 760528 | p.Gln241Arg | missense_variant | 0.94 | rifampicin | |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.93 | rifampicin | |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoB | 760577 | c.771G>A | synonymous_variant | 0.98 | rifampicin | |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.97 | rifampicin | |
rpoB | 760604 | c.798G>A | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760607 | c.801G>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 760625 | c.819C>A | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 760664 | c.858G>C | synonymous_variant | 0.89 | rifampicin | |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 760673 | c.867G>A | synonymous_variant | 0.87 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>T | synonymous_variant | 0.73 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.82 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.91 | rifampicin | |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Ala | missense_variant | 0.98 | rifampicin | |
rpoB | 760859 | c.1053T>G | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760868 | c.1062C>G | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760920 | c.1114C>T | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 760971 | c.1165C>A | synonymous_variant | 0.93 | rifampicin | |
rpoB | 760994 | c.1188G>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761006 | c.1200C>T | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>A | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761066 | c.1260G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761096 | c.1290G>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761132 | c.1326G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>T | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761183 | c.1377T>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761201 | c.1395G>A | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761204 | c.1398C>G | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761234 | c.1428G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761273 | c.1467T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761300 | c.1494G>A | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761318 | c.1512G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761346 | p.Val514Ile | missense_variant | 0.95 | rifampicin | |
rpoB | 761384 | c.1578C>G | synonymous_variant | 0.85 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.91 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761438 | c.1632G>T | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761441 | p.Asp545Glu | missense_variant | 0.92 | rifampicin | Uncertain significance |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.85 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761471 | c.1665C>G | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761483 | c.1677G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761502 | p.Pro566Ala | missense_variant | 0.97 | rifampicin | |
rpoB | 761510 | c.1704T>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761600 | c.1794T>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761603 | c.1797C>T | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761682 | c.1876C>T | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761687 | c.1881C>T | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761693 | c.1887G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761708 | c.1902C>T | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.91 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.95 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.95 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.97 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761819 | c.2013G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761822 | c.2016C>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.89 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.78 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.77 | rifampicin | |
rpoB | 761864 | c.2058G>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 761867 | c.2061C>A | synonymous_variant | 0.77 | rifampicin | |
rpoB | 761870 | p.Asp688Glu | missense_variant | 0.81 | rifampicin | |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761876 | c.2070C>A | synonymous_variant | 0.85 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761913 | c.2107_2109delGACinsCG | frameshift_variant&missense_variant | 0.9 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.91 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761990 | c.2184G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.92 | rifampicin | |
rpoB | 762011 | c.2205G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 762020 | c.2214G>A | synonymous_variant | 0.93 | rifampicin | |
rpoB | 762024 | c.2218_2220delGTGinsAC | frameshift_variant&missense_variant | 0.92 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 762071 | c.2265C>T | synonymous_variant | 0.96 | rifampicin | |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.97 | rifampicin | Uncertain significance |
rpoB | 762119 | c.2313C>T | synonymous_variant | 0.97 | rifampicin | |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 762134 | c.2328C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 762224 | c.2418C>G | synonymous_variant | 0.99 | rifampicin | |
rpoB | 762236 | c.2430G>A | synonymous_variant | 0.99 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 762269 | c.2463G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762278 | c.2472C>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.91 | rifampicin | |
rpoB | 762369 | c.2563_2565delTTGinsCT | frameshift_variant&synonymous_variant | 0.91 | rifampicin | |
rpoC | 762374 | c.-996G>C | upstream_gene_variant | 0.91 | rifampicin | |
rpoC | 762380 | c.-990T>C | upstream_gene_variant | 0.92 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.96 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.95 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.95 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.95 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.96 | rifampicin | |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 762486 | p.Pro894Ala | missense_variant | 0.92 | rifampicin | |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.91 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.92 | rifampicin | |
rpoC | 762518 | c.-852C>G | upstream_gene_variant | 0.93 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.92 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.93 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.93 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.89 | rifampicin | |
rpoC | 762557 | c.-813G>C | upstream_gene_variant | 0.89 | rifampicin | |
rpoC | 762581 | c.-789T>C | upstream_gene_variant | 0.88 | rifampicin | |
rpoC | 762582 | c.-788T>C | upstream_gene_variant | 0.88 | rifampicin | |
rpoC | 762587 | c.-783G>A | upstream_gene_variant | 0.85 | rifampicin | |
rpoC | 762599 | c.-771T>A | upstream_gene_variant | 0.74 | rifampicin | |
rpoC | 762605 | c.-765T>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 762608 | c.-762C>G | upstream_gene_variant | 0.67 | rifampicin | |
rpoC | 762617 | c.-753C>G | upstream_gene_variant | 0.46 | rifampicin | |
rpoC | 762710 | c.-660G>T | upstream_gene_variant | 0.81 | rifampicin | |
rpoB | 762740 | c.2934G>A | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 762749 | c.-621C>G | upstream_gene_variant | 0.93 | rifampicin | |
rpoC | 762758 | c.-612G>A | upstream_gene_variant | 0.93 | rifampicin | |
rpoB | 762760 | p.Cys985Ser | missense_variant | 0.93 | rifampicin | Uncertain significance |
rpoC | 762764 | c.-606G>A | upstream_gene_variant | 0.96 | rifampicin | |
rpoC | 762765 | c.-605C>T | upstream_gene_variant | 0.96 | rifampicin | |
rpoC | 762776 | c.-594C>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 762813 | c.3007_3009delATGinsGC | frameshift_variant&missense_variant | 0.93 | rifampicin | |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 762830 | c.-540C>T | upstream_gene_variant | 0.96 | rifampicin | |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 762860 | c.-510G>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 762899 | c.3093G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763050 | c.-320C>T | upstream_gene_variant | 0.98 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763076 | c.-294C>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 763094 | c.3288G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763124 | c.-246C>T | upstream_gene_variant | 0.98 | rifampicin | |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.99 | rifampicin | |
rpoB | 763193 | c.3387C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.97 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.92 | rifampicin | |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.92 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
rpoC | 763375 | c.6C>A | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 763408 | c.39T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763430 | c.61A>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763435 | c.66A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763505 | c.136C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763561 | c.192G>A | synonymous_variant | 0.93 | rifampicin | |
rpoC | 763600 | c.231C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 763606 | c.237C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763618 | c.249C>A | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763639 | c.270G>A | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763658 | c.289_291delCTTinsTG | frameshift_variant&missense_variant | 0.93 | rifampicin | |
rpoC | 763666 | c.297G>A | synonymous_variant | 0.93 | rifampicin | |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 763699 | c.330G>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763771 | c.402C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763781 | p.Ser138Ala | missense_variant | 0.98 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763819 | c.450G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.98 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.94 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.94 | rifampicin | |
rpoC | 763916 | p.Glu183Gln | missense_variant | 0.96 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763948 | c.579G>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763951 | c.582G>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 0.99 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 0.97 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Gln | missense_variant | 0.99 | rifampicin | |
rpoC | 764119 | c.750G>A | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764161 | c.792G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.92 | rifampicin | |
rpoC | 764206 | p.Asp279Glu | missense_variant | 0.92 | rifampicin | |
rpoC | 764217 | p.Asn283Ser | missense_variant | 0.92 | rifampicin | |
rpoC | 764254 | c.885G>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764272 | c.903G>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 764284 | c.915G>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 764317 | c.948C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 764344 | c.975C>T | synonymous_variant | 0.93 | rifampicin | |
rpoC | 764347 | c.978G>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.92 | rifampicin | |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoC | 764404 | c.1035C>A | synonymous_variant | 0.85 | rifampicin | |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.91 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 0.88 | rifampicin | |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.88 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.88 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764524 | c.1155C>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764533 | c.1164C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764536 | c.1167G>A | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764587 | c.1218C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764648 | c.1279C>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764653 | c.1284G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764656 | c.1287C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764674 | c.1305G>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764681 | c.1312C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764746 | c.1377G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764755 | c.1386C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764767 | c.1398G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764800 | c.1431G>A | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764833 | c.1464A>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764875 | c.1506C>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519_1521delTTGinsCC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
rpoC | 764902 | c.1533C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764918 | c.1549_1551delGTGinsAC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoC | 765052 | c.1683C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 765067 | c.1698G>C | synonymous_variant | 0.87 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 765079 | c.1710T>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 765085 | c.1716T>C | synonymous_variant | 0.83 | rifampicin | |
rpoC | 765088 | c.1719G>C | synonymous_variant | 0.83 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 765100 | c.1731G>C | synonymous_variant | 0.8 | rifampicin | |
rpoC | 765103 | c.1734G>A | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 765115 | c.1746G>A | synonymous_variant | 0.8 | rifampicin | |
rpoC | 765122 | c.1753C>T | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765208 | c.1839T>C | synonymous_variant | 0.77 | rifampicin | |
rpoC | 765217 | c.1848C>G | synonymous_variant | 0.82 | rifampicin | |
rpoC | 765223 | c.1854G>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765232 | c.1863G>C | synonymous_variant | 0.87 | rifampicin | |
rpoC | 765245 | c.1877_1878insGCT | disruptive_inframe_insertion | 0.83 | rifampicin | |
rpoC | 765249 | p.Leu627Ser | missense_variant | 0.78 | rifampicin | |
rpoC | 765250 | c.1882_1884delAGC | conservative_inframe_deletion | 0.81 | rifampicin | |
rpoC | 765287 | c.1918C>T | synonymous_variant | 0.77 | rifampicin | |
rpoC | 765292 | c.1923G>T | synonymous_variant | 0.74 | rifampicin | |
rpoC | 765296 | c.1927_1929delCCGinsTT | frameshift_variant&missense_variant | 0.74 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.7 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 765325 | c.1956C>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 765330 | p.Ser654Asn | missense_variant | 0.47 | rifampicin | Uncertain significance |
rpoC | 765340 | p.Gln657His | missense_variant | 0.65 | rifampicin | |
rpoC | 765349 | p.Asp660Glu | missense_variant | 0.75 | rifampicin | |
rpoC | 765350 | c.1981_1983delGCGinsCC | frameshift_variant&missense_variant | 0.75 | rifampicin | |
rpoC | 765358 | p.Met663Ile | missense_variant | 0.81 | rifampicin | Uncertain significance |
rpoC | 765364 | p.Glu665Asp | missense_variant | 0.81 | rifampicin | |
rpoC | 765367 | c.1998C>G | synonymous_variant | 0.82 | rifampicin | |
rpoC | 765376 | c.2007C>G | synonymous_variant | 0.89 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.89 | rifampicin | Uncertain significance |
rpoC | 765395 | c.2026C>T | synonymous_variant | 0.91 | rifampicin | |
rpoC | 765405 | p.Leu679Pro | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 765430 | c.2061G>A | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765445 | c.2076G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 0.97 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765496 | c.2127C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765526 | c.2157C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 765541 | c.2172C>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765547 | c.2178C>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 765586 | c.2217G>A | synonymous_variant | 0.95 | rifampicin | |
rpoC | 765589 | c.2220G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 765610 | c.2241C>T | synonymous_variant | 0.94 | rifampicin | |
rpoC | 765612 | p.His748Arg | missense_variant | 0.94 | rifampicin | |
rpoC | 765622 | p.Glu751Asp | missense_variant | 0.96 | rifampicin | |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 765676 | c.2307G>A | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765688 | c.2319G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765689 | c.2320C>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765694 | c.2325G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 765724 | c.2355C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 765727 | c.2358T>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765748 | c.2379C>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765752 | p.Asp795Ser | missense_variant | 0.97 | rifampicin | |
rpoC | 765757 | c.2388C>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765790 | c.2421C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>A | synonymous_variant | 0.99 | rifampicin | |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765910 | c.2541G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765934 | c.2565C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765952 | c.2583G>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765997 | c.2628T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766043 | p.Gln892Gly | missense_variant | 0.93 | rifampicin | |
rpoC | 766070 | c.2701C>T | synonymous_variant | 0.89 | rifampicin | Not assoc w R |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.78 | rifampicin | |
rpoC | 766089 | c.2720_2721delACinsGGGTTGATGGGCAA | missense_variant&conservative_inframe_insertion | 0.58 | rifampicin | |
rpoC | 766092 | p.Gly908Val | missense_variant | 0.58 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766243 | c.2874C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766249 | c.2880C>A | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766255 | c.2886G>T | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766270 | c.2901G>C | synonymous_variant | 0.82 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.86 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.88 | rifampicin | |
rpoC | 766300 | c.2931C>G | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoC | 766306 | c.2937C>T | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>C | synonymous_variant | 0.9 | rifampicin | |
rpoC | 766315 | c.2946C>G | synonymous_variant | 0.9 | rifampicin | |
rpoC | 766324 | c.2955C>T | synonymous_variant | 0.94 | rifampicin | |
rpoC | 766351 | c.2982C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766360 | c.2991C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766387 | c.3018C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766397 | c.3028C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766417 | c.3048C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766519 | c.3150C>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766534 | c.3165C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766537 | c.3168G>A | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766549 | c.3180G>T | synonymous_variant | 0.92 | rifampicin | |
rpoC | 766570 | c.3201T>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.93 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.93 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.95 | rifampicin | |
rpoC | 766621 | c.3252G>A | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766654 | c.3285C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766681 | c.3312C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766684 | c.3315C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766700 | c.3331C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766714 | c.3345G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766747 | c.3378C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766792 | c.3423C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 766795 | c.3426C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766801 | c.3432C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766903 | c.3534C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766907 | c.3538C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766918 | c.3549C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766921 | c.3552G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766975 | c.3606C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 767002 | c.3633G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>T | synonymous_variant | 0.93 | rifampicin | |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.93 | rifampicin | |
rpoC | 767185 | c.3816G>T | synonymous_variant | 0.93 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 767200 | c.3831G>A | synonymous_variant | 0.94 | rifampicin | |
rpoC | 767206 | c.3837C>A | synonymous_variant | 0.93 | rifampicin | |
rpoC | 767209 | c.3840T>G | synonymous_variant | 0.93 | rifampicin | |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.92 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.9 | rifampicin | |
rpoC | 767275 | c.3906T>A | synonymous_variant | 0.89 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>T | synonymous_variant | 0.89 | rifampicin | |
rpoC | 767287 | c.3918G>A | synonymous_variant | 0.89 | rifampicin | |
rpoC | 767317 | c.3948C>G | synonymous_variant | 0.7 | rifampicin | |
rpsL | 781571 | c.12C>T | synonymous_variant | 0.88 | streptomycin | |
rpsL | 781586 | c.27C>A | synonymous_variant | 0.94 | streptomycin | |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.95 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.97 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.97 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.95 | streptomycin | |
rpsL | 781658 | c.99A>G | synonymous_variant | 0.94 | streptomycin | |
rpsL | 781664 | c.105C>T | synonymous_variant | 0.94 | streptomycin | |
rpsL | 781667 | c.108C>G | synonymous_variant | 0.94 | streptomycin | |
rpsL | 781709 | c.150G>C | synonymous_variant | 0.97 | streptomycin | Not assoc w R - Interim |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781718 | c.159C>G | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781721 | c.162C>G | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.97 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.92 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.91 | streptomycin | |
rpsL | 781847 | c.288G>A | synonymous_variant | 0.92 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.91 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.92 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.92 | streptomycin | |
rpsL | 781877 | c.318T>A | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781880 | c.321C>G | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.91 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.95 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.95 | streptomycin | Uncertain significance |
rplC | 800209 | c.-600C>T | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800224 | c.-585G>C | upstream_gene_variant | 0.93 | linezolid | |
rplC | 800225 | c.-584T>C | upstream_gene_variant | 0.93 | linezolid | |
rplC | 800237 | c.-572T>C | upstream_gene_variant | 0.92 | linezolid | |
rplC | 800244 | c.-565A>G | upstream_gene_variant | 0.92 | linezolid | |
rplC | 800267 | c.-542T>C | upstream_gene_variant | 0.91 | linezolid | |
rplC | 800272 | c.-537C>T | upstream_gene_variant | 0.91 | linezolid | |
rplC | 800278 | c.-531A>G | upstream_gene_variant | 0.89 | linezolid | |
rplC | 800285 | c.-524_-523insC | upstream_gene_variant | 0.92 | linezolid | |
rplC | 800295 | c.-513_-502delCTTGAAATTGAT | upstream_gene_variant | 0.71 | linezolid | |
rplC | 800311 | c.-498delGinsCT | upstream_gene_variant | 0.71 | linezolid | |
rplC | 800321 | c.-488T>C | upstream_gene_variant | 0.79 | linezolid | |
rplC | 800341 | c.-468G>C | upstream_gene_variant | 0.82 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.99 | linezolid | |
rplC | 800579 | c.-230C>T | upstream_gene_variant | 0.99 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.99 | linezolid | |
rplC | 800597 | c.-212A>G | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800600 | c.-209G>T | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800609 | c.-200G>A | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800693 | c.-116A>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800714 | c.-95C>T | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800735 | c.-74C>G | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800744 | c.-65G>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800759 | c.-50C>T | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800783 | c.-26C>T | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800797 | c.-12T>G | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800799 | c.-10G>C | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800800 | c.-9G>T | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800801 | c.-8A>G | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800817 | c.9A>C | synonymous_variant | 0.95 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.97 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.96 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.96 | linezolid | |
rplC | 800877 | c.69A>C | synonymous_variant | 0.98 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.96 | linezolid | |
rplC | 800913 | c.105G>C | synonymous_variant | 0.96 | linezolid | |
rplC | 800916 | c.108A>T | synonymous_variant | 0.96 | linezolid | |
rplC | 800922 | c.114C>G | synonymous_variant | 0.96 | linezolid | |
rplC | 800934 | c.126C>G | synonymous_variant | 0.96 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.96 | linezolid | |
rplC | 800946 | c.138T>G | synonymous_variant | 0.95 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 0.95 | linezolid | |
rplC | 800955 | c.147C>G | synonymous_variant | 0.94 | linezolid | |
rplC | 800958 | c.150G>A | synonymous_variant | 0.94 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 0.92 | linezolid | Not assoc w R - Interim |
rplC | 800976 | c.168G>A | synonymous_variant | 0.94 | linezolid | |
rplC | 800982 | c.174C>T | synonymous_variant | 0.93 | linezolid | |
rplC | 801117 | c.309G>C | synonymous_variant | 0.8 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801144 | c.336C>G | synonymous_variant | 0.94 | linezolid | |
rplC | 801147 | c.339T>C | synonymous_variant | 0.96 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 0.96 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.95 | linezolid | |
rplC | 801201 | c.393C>T | synonymous_variant | 0.96 | linezolid | |
rplC | 801210 | c.402T>C | synonymous_variant | 0.96 | linezolid | |
rplC | 801216 | c.408C>A | synonymous_variant | 0.96 | linezolid | |
rplC | 801219 | c.411C>T | synonymous_variant | 0.96 | linezolid | |
rplC | 801220 | p.Ser138Ala | missense_variant | 0.97 | linezolid | |
rplC | 801246 | c.438C>G | synonymous_variant | 0.98 | linezolid | |
rplC | 801252 | c.444G>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.96 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.97 | linezolid | |
rplC | 801297 | c.489C>T | synonymous_variant | 0.96 | linezolid | Not assoc w R - Interim |
rplC | 801312 | c.504G>C | synonymous_variant | 0.96 | linezolid | |
rplC | 801339 | c.531T>G | synonymous_variant | 0.96 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.96 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.96 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.95 | linezolid | |
rplC | 801372 | c.564G>A | synonymous_variant | 0.97 | linezolid | |
rplC | 801385 | c.577C>T | synonymous_variant | 0.96 | linezolid | |
rplC | 801396 | c.588T>C | synonymous_variant | 0.96 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801417 | c.609T>C | synonymous_variant | 0.95 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.95 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.95 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.82 | linezolid | |
rplC | 801447 | c.639A>G | synonymous_variant | 0.8 | linezolid | |
Rv1129c | 1253450 | p.Ser362Asn | missense_variant | 0.75 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253461 | c.1074G>C | synonymous_variant | 0.75 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253464 | c.1069_1071delAGCinsTCT | synonymous_variant | 0.75 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253476 | c.1059G>A | synonymous_variant | 0.75 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253482 | c.1053G>C | synonymous_variant | 0.69 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253491 | c.1044A>C | synonymous_variant | 0.82 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253494 | c.1041G>A | synonymous_variant | 0.82 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253509 | c.1026C>A | synonymous_variant | 0.75 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv1129c | 1253512 | p.Lys341Ser | missense_variant | 0.75 | moxifloxacin | |
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
fbiC | 1303431 | c.501T>C | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303441 | c.511T>C | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303464 | c.534A>G | synonymous_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303467 | c.537C>A | synonymous_variant | 0.78 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303470 | c.540T>G | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303476 | c.546G>A | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303479 | c.549G>A | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303480 | p.Gln184Glu | missense_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303488 | c.558G>C | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303503 | c.573G>C | synonymous_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>G | synonymous_variant | 0.89 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303551 | c.621G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303578 | c.648G>A | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303584 | c.654C>A | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303591 | c.661C>A | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303594 | c.664C>T | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303611 | c.681G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303614 | c.684C>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303620 | c.690C>T | synonymous_variant | 0.92 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303644 | c.714G>T | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303661 | p.Val244Ala | missense_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303689 | c.759T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Thr | missense_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303768 | p.Ser280Ala | missense_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303794 | c.864A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303956 | p.Glu342Asp | missense_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303973 | p.Gly348Ala | missense_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303980 | c.1050G>T | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304049 | c.1119T>G | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304055 | p.Asp375Glu | missense_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304058 | p.Glu376Asp | missense_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
fbiC | 1304059 | c.1129C>T | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304079 | c.1149A>G | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304091 | c.1161C>T | synonymous_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304112 | c.1182G>A | synonymous_variant | 0.89 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304120 | p.Lys397Arg | missense_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304124 | c.1194C>T | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304127 | c.1197A>G | synonymous_variant | 0.89 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304142 | c.1212G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304163 | c.1233G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304164 | p.Gly412Arg | missense_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304172 | c.1242G>T | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304174 | p.Val415Ala | missense_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304178 | c.1248G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304181 | c.1251G>T | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304184 | c.1254G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304205 | c.1275C>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304208 | c.1278C>T | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304217 | p.Asn429Lys | missense_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304499 | c.1569T>A | synonymous_variant | 0.89 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304502 | c.1572G>A | synonymous_variant | 0.9 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304511 | c.1581C>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304520 | c.1590A>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304546 | p.Val539Ala | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304556 | c.1626C>T | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304598 | c.1668C>T | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304628 | c.1698G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304649 | c.1719C>T | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304679 | c.1749G>A | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>T | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304715 | c.1785G>T | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304751 | c.1821C>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304790 | c.1860C>A | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304799 | c.1869G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304809 | p.Ser627Glu | missense_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.91 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.87 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304901 | c.1971C>T | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304915 | p.Asp662Gly | missense_variant | 0.86 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304922 | c.1992C>T | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304934 | c.2004C>G | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304943 | c.2013C>T | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.87 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.78 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | c.2065T>C | synonymous_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305001 | p.Ile691Val | missense_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305027 | c.2097G>A | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305036 | c.2106G>A | synonymous_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305045 | c.2115A>G | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305051 | c.2121G>C | synonymous_variant | 0.86 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305066 | c.2136T>C | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305069 | c.2139G>C | synonymous_variant | 0.87 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305074 | p.Ser715Thr | missense_variant | 0.86 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305078 | c.2148A>C | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305088 | p.Val720Ile | missense_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305096 | c.2166T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305099 | c.2169T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305111 | c.2181C>T | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1305117 | c.2187T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305120 | c.2190G>A | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305126 | c.2196T>C | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1305150 | c.2220C>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305154 | c.2224T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305159 | c.2229G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305162 | c.2232C>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305165 | c.2235G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305186 | c.2256C>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305192 | c.2262C>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305195 | c.2265T>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305204 | c.2274C>A | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305215 | p.Ser762Thr | missense_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305219 | p.His763Gln | missense_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305231 | c.2301C>G | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305237 | c.2307A>G | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305240 | c.2310T>C | synonymous_variant | 0.86 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305243 | c.2313T>A | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305244 | c.2314T>C | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305259 | c.2329T>C | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305375 | c.2445C>G | synonymous_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305393 | c.2463T>C | synonymous_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>T | synonymous_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305423 | c.2493T>C | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364796 | c.384G>A | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364802 | c.390C>G | synonymous_variant | 0.95 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.94 | pyrazinamide | |
sigE | 1364818 | c.406_408delCTAinsTG | frameshift_variant&stop_gained | 0.94 | pyrazinamide | Uncertain significance |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364844 | c.432C>T | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364847 | c.435G>C | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364866 | c.454_456delGCTinsAC | frameshift_variant&missense_variant | 0.96 | pyrazinamide | Uncertain significance |
sigE | 1364889 | c.477A>G | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364898 | c.486C>T | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364913 | c.501C>T | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364922 | p.Glu170Asp | missense_variant | 0.97 | pyrazinamide | |
sigE | 1364943 | c.531C>T | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364955 | c.543G>T | synonymous_variant | 0.95 | pyrazinamide | |
sigE | 1364961 | c.549A>G | synonymous_variant | 0.94 | pyrazinamide | |
sigE | 1364964 | c.552T>C | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364967 | c.555C>T | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364968 | c.556C>T | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364980 | c.568_570delTTGinsCC | frameshift_variant&missense_variant | 0.93 | pyrazinamide | Uncertain significance |
sigE | 1364984 | p.Ala191Asp | missense_variant | 0.93 | pyrazinamide | |
Rv1258c | 1406270 | c.1071C>T | synonymous_variant | 0.95 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406291 | c.1050G>A | synonymous_variant | 0.95 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406297 | c.1044A>G | synonymous_variant | 0.95 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406314 | p.His343Tyr | missense_variant | 0.93 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406315 | p.Gln342His | missense_variant | 0.93 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406318 | c.1021_1023delGCAinsCG | frameshift_variant&synonymous_variant | 0.93 | streptomycin | Uncertain significance |
isoniazid | Uncertain significance | |||||
pyrazinamide | Uncertain significance | |||||
Rv1258c | 1406327 | c.1014G>C | synonymous_variant | 0.87 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406330 | c.1011G>A | synonymous_variant | 0.87 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406333 | p.Ile336Met | missense_variant | 0.87 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406345 | c.996T>C | synonymous_variant | 0.81 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406351 | c.990G>C | synonymous_variant | 0.76 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406360 | c.981C>G | synonymous_variant | 0.64 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406553 | p.Ala263Val | missense_variant | 0.85 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406556 | p.Trp262Ser | missense_variant | 0.85 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406558 | c.783T>C | synonymous_variant | 0.85 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406567 | p.Val258Ala | missense_variant | 0.73 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 14065 |