TB-Profiler result

Run: ERR158583
Summary

Run ID: ERR158583

Sample name:

Date: 2024-04-15T23:34:03.989672

Number of reads: 1781558

Percentage reads mapped: 25.87

Median coverage: 33.0

Strain: La3;M.canetti;lineage2;lineage4.2;lineage4.3

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.1.2 Indo-Oceanic RD239 0.12
lineage4.3 Euro-American (LAM) None 0.08
lineage2 East-Asian RD105 0.18
lineage4.2 Euro-American None 0.18
lineage4.6.4 Euro-American None 0.23
La3 M.orygis None 0.06
M.canetti M.canetti None 0.17
lineage4.8.2 Euro-American (mainly T) RD219 0.06
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Thr437Ala Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.1dupG Assoc w R
kanamycin
cycloserine
ethionamide ethA c.1015_1017delATTinsGC Assoc w R
c.751_753delAGCinsGG Assoc w R
c.478_480delCCGinsGC Assoc w R
p.Glu39* Assoc w R
clofazimine pepQ c.865_867delCACinsAT Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.562_564delTTGinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1018_1020delGGCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1144_1146delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1270_1272delCTGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1591_1593delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2344_2346delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD c.364_366delACAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.706_708delGCAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1150_1152delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.316_318delGTGinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.865_867delCACinsAT Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsCG frameshift_variant&missense_variant 0.93 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.91 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303492 c.562_564delTTGinsCT frameshift_variant&synonymous_variant 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsAG frameshift_variant&missense_variant 0.86 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303948 c.1018_1020delGGCinsCG frameshift_variant&missense_variant 0.7 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 0.7 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304074 c.1144_1146delGCCinsTG frameshift_variant&missense_variant 0.76 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304200 c.1270_1272delCTGinsTC frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304521 c.1591_1593delCTGinsGA frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305274 c.2344_2346delTCGinsGC frameshift_variant&missense_variant 0.73 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
tlyA 1917939 c.1dupG frameshift_variant 0.86 capreomycin Assoc w R
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.91 isoniazid Assoc w R High-level resistance
pepQ 2859552 c.865_867delCACinsAT frameshift_variant&synonymous_variant 0.89 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
fbiD 3339481 c.364_366delACAinsCG frameshift_variant&missense_variant 0.73 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641248 c.706_708delGCAinsAC frameshift_variant&missense_variant 0.85 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642684 c.1150_1152delTTGinsCA frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987159 c.316_318delGTGinsAT frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.94 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.96 ethambutol Mutation from literature
embB 4247822 p.Thr437Ala missense_variant 0.94 ethambutol Mutation from literature
ethA 4326457 c.1015_1017delATTinsGC frameshift_variant&missense_variant 0.7 ethionamide Assoc w R
ethA 4326721 c.751_753delAGCinsGG frameshift_variant&missense_variant 0.64 ethionamide Assoc w R
ethA 4326994 c.478_480delCCGinsGC frameshift_variant&missense_variant 0.73 ethionamide Assoc w R
ethA 4327359 p.Glu39* stop_gained 0.72 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 0.82 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.86 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 0.88 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 0.88 isoniazid Uncertain significance
dnaA 753 c.753C>T synonymous_variant 0.88 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.88 isoniazid
dnaA 762 c.762C>T synonymous_variant 0.88 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.93 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.94 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 0.91 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.9 isoniazid Uncertain significance
dnaA 810 c.810C>G synonymous_variant 0.9 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.9 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.94 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.95 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.95 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 849 c.849A>G synonymous_variant 0.98 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.97 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.97 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.95 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.95 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.97 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.97 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.93 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.96 isoniazid
dnaA 939 c.939C>A synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 945 c.945G>A synonymous_variant 0.94 isoniazid
dnaA 955 c.955_957delAGAinsCG frameshift_variant&synonymous_variant 0.85 isoniazid Uncertain significance
dnaA 963 c.963C>G synonymous_variant 0.83 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.83 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.83 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.83 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 987 c.987C>T synonymous_variant 0.83 isoniazid
dnaA 990 c.990A>G synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.83 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 0.85 isoniazid
dnaA 1003 c.1003C>T synonymous_variant 0.88 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.93 isoniazid
dnaA 1059 c.1059C>A synonymous_variant 0.92 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.97 isoniazid
dnaA 1083 c.1083C>T synonymous_variant 0.97 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.97 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.97 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 0.96 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1143 c.1143G>A synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 1149 c.1149C>T synonymous_variant 0.85 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.85 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.85 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.88 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.88 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 1179 c.1179G>C synonymous_variant 0.94 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.92 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 0.92 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.92 isoniazid
dnaA 1200 c.1200C>T synonymous_variant 0.89 isoniazid
dnaA 1206 c.1206G>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Thr missense_variant 0.91 isoniazid
dnaA 1222 p.Thr408Ala missense_variant 0.91 isoniazid Uncertain significance
dnaA 1245 c.1245G>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.93 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.92 isoniazid
dnaA 1281 c.1281C>G synonymous_variant 0.9 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.9 isoniazid
dnaA 1299 c.1299G>A synonymous_variant 0.9 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.89 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 0.89 isoniazid
dnaA 1315 c.1315_1317delGCAinsTG frameshift_variant&stop_gained 0.83 isoniazid Uncertain significance
dnaA 1332 c.1332A>C synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.8 isoniazid
dnaA 1350 c.1350G>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 0.76 isoniazid
dnaA 1356 c.1356T>G synonymous_variant 0.77 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.82 isoniazid
dnaA 1374 c.1374G>T synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 1375 c.1375T>C synonymous_variant 0.82 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.86 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.88 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.89 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.89 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.89 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.93 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.96 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.98 isoniazid
dnaA 1458 c.1458G>A synonymous_variant 0.95 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.95 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 1488 c.1488A>G synonymous_variant 0.88 isoniazid
dnaA 1494 c.1494C>G synonymous_variant 0.82 isoniazid
dnaA 1497 c.1497T>A synonymous_variant 0.81 isoniazid
dnaA 1498 c.1498_1500delCGCinsAG frameshift_variant&missense_variant 0.81 isoniazid Uncertain significance
gyrB 5229 c.-11G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrB 5230 c.-10T>C upstream_gene_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 5238 c.-2T>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 5254 c.15A>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5284 c.45G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5293 c.54C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5302 c.63A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5305 c.66G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5308 c.69G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5359 c.120C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 0.87 levofloxacin Uncertain significance
moxifloxacin
gyrB 5377 c.138T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5422 c.183T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5425 c.186A>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5426 p.Thr63Ala missense_variant 0.77 levofloxacin
moxifloxacin
gyrB 5431 c.192A>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 5434 c.195G>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5436 p.Asn66Ser missense_variant 0.82 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 5440 c.201A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 5449 c.210T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrB 5455 c.216T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5470 c.231C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 5485 c.246C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5488 c.249C>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5491 c.252T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5500 c.261C>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 5502 p.Thr88Met missense_variant 0.85 levofloxacin
moxifloxacin
gyrB 5527 c.288C>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrB 5542 c.303A>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5545 c.306A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5548 c.309A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5551 c.312T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5560 c.321C>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5569 c.330C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 5572 c.333G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 5710 c.471C>A synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5722 c.483G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5731 c.492C>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5740 c.501G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 5743 c.504G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 5744 c.505_507delTCAinsAG frameshift_variant&missense_variant 0.86 levofloxacin Uncertain significance
moxifloxacin
gyrB 5767 c.528C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5771 p.Ala178Asn missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 5779 c.540C>T synonymous_variant 0.89 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 5782 c.543A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5788 c.549G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5791 c.552A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5812 c.573C>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5815 c.576C>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5819 c.580C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5824 c.585A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5836 c.597C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 5851 c.612G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5860 c.621C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5869 c.630C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5870 p.Glu211Gln missense_variant 0.93 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5884 c.645A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 5926 c.687G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5929 c.690G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6049 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6079 c.840C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6085 c.846C>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.94 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.96 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6421 c.-881C>T upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.71 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6801 p.Lys521Arg missense_variant 0.71 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6826 c.-476G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6886 c.-416C>T upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>T upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>A upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7151 c.1912C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7165 c.-137C>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7207 c.-95C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7219 c.-83C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7231 c.-71C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7340 p.Asp13Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7652 c.351C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7703 c.402G>A synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7715 c.414G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 7940 c.639G>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7941 p.Glu214Thr missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7958 c.657C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 7970 c.669T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7973 c.672A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7988 c.687G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7997 c.696A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8000 c.699G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8030 c.729C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8042 c.741C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8048 c.747C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8105 c.804G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsGG frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8282 c.981G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 0.85 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.99 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9065 c.1764C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9218 c.1917C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9476 c.2175G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9545 c.2244A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9551 c.2250G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9585 c.2284T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9722 c.2421C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
Rv0010c 13879 c.-321T>G upstream_gene_variant 0.82 isoniazid
Rv0010c 13891 c.-333G>C upstream_gene_variant 0.9 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.94 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.91 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.91 isoniazid
fgd1 490781 c.-2T>G upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490782 c.-1G>A upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490809 c.27A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490853 p.Ala24Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490863 c.81C>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490945 c.163C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490984 p.Leu68Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491154 p.Glu124Asp missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491265 c.483G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.83 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 0.73 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491298 c.516C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 0.76 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491331 c.549G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.72 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491453 p.Gly224Asp missense_variant 0.7 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491478 c.696G>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491487 c.705C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
mshA 575506 c.159C>T synonymous_variant 0.8 ethionamide
isoniazid
mshA 575512 c.165A>G synonymous_variant 0.77 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.9 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575545 c.198C>T synonymous_variant 0.93 ethionamide
isoniazid
mshA 575548 c.201C>A synonymous_variant 0.95 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.96 ethionamide
isoniazid
mshA 575572 c.225T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 575629 c.282A>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575633 c.286_288delGCAinsAG frameshift_variant&missense_variant 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575652 p.Arg102Gln missense_variant 0.9 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.89 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575671 c.324G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575686 c.339G>A synonymous_variant 0.9 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.95 ethionamide
isoniazid
mshA 575732 c.385_387delCTTinsTG frameshift_variant&missense_variant 0.95 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575737 c.390T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.92 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575851 c.504C>T synonymous_variant 0.94 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575878 c.531A>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575892 p.Ala182Val missense_variant 0.94 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 0.94 ethionamide
isoniazid Not assoc w R - Interim
mshA 575908 c.561A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 0.86 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.84 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 0.74 ethionamide
isoniazid
ccsA 619579 c.-312G>C upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619597 c.-294G>C upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619624 c.-267C>T upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619648 c.-243C>G upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619681 c.-210G>A upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194A>C upstream_gene_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 619708 c.-183G>C upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619713 c.-178_-177delCGinsTC upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619720 c.-171C>T upstream_gene_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 619727 c.-164_-162delACGinsGC upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619734 c.-157_-156delCGinsATACCCCC upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619744 c.-147A>G upstream_gene_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 619766 c.-125A>G upstream_gene_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 619771 c.-120C>G upstream_gene_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620214 c.324C>A synonymous_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620290 p.Tyr134Asn missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620314 c.424C>T synonymous_variant 0.95 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620325 c.435G>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620404 c.514C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.92 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620487 c.597C>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>C synonymous_variant 0.78 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620545 p.Leu219Phe missense_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620571 c.681A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>A synonymous_variant 0.99 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620622 c.732G>C synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>T synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 0.96 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620760 c.870C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.95 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620829 c.939G>T synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620838 c.948C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620839 c.949C>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620847 c.957G>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620853 c.963G>T synonymous_variant 0.79 capreomycin
amikacin
kanamycin
Rv0565c 656031 c.1440A>G synonymous_variant 0.8 ethionamide
Rv0565c 656052 c.1419A>G synonymous_variant 0.77 ethionamide Not assoc w R - Interim
Rv0565c 656067 c.1404C>T synonymous_variant 0.86 ethionamide
Rv0565c 656073 p.Leu466Phe missense_variant 0.87 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 0.88 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 0.89 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.89 ethionamide
Rv0565c 656103 c.1368G>A synonymous_variant 0.88 ethionamide
Rv0565c 656112 c.1359C>A synonymous_variant 0.9 ethionamide
Rv0565c 656116 p.Lys452Arg missense_variant 0.89 ethionamide
Rv0565c 656129 p.Tyr448His missense_variant 0.91 ethionamide
Rv0565c 656131 p.Pro447Leu missense_variant 0.9 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 0.95 ethionamide
Rv0565c 656136 c.1335G>C synonymous_variant 0.95 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 0.95 ethionamide
Rv0565c 656169 c.1302G>C synonymous_variant 0.9 ethionamide
Rv0565c 656262 c.1209C>G synonymous_variant 1.0 ethionamide
Rv0565c 656277 c.1194C>T synonymous_variant 1.0 ethionamide
Rv0565c 656282 c.1189C>T synonymous_variant 0.97 ethionamide Not assoc w R - Interim
Rv0565c 656295 c.1176C>T synonymous_variant 0.97 ethionamide
Rv0565c 656301 c.1170C>T synonymous_variant 0.97 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.97 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 0.91 ethionamide
Rv0565c 656876 p.Leu199Met missense_variant 0.59 ethionamide
Rv0565c 656880 c.591C>G synonymous_variant 0.63 ethionamide
Rv0565c 656889 c.582A>G synonymous_variant 0.68 ethionamide
Rv0565c 656895 c.576G>C synonymous_variant 0.71 ethionamide
Rv0565c 656922 c.547_549delATCinsGG frameshift_variant&missense_variant 0.68 ethionamide Uncertain significance
Rv0565c 656936 p.Thr179Ala missense_variant 0.75 ethionamide
Rv0565c 656964 c.507C>G synonymous_variant 0.8 ethionamide
Rv0565c 656973 c.498A>G synonymous_variant 0.81 ethionamide
Rv0565c 657023 p.Glu150Gln missense_variant 0.75 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 0.71 ethionamide
Rv0565c 657066 c.405C>T synonymous_variant 0.67 ethionamide Not assoc w R - Interim
Rv0565c 657070 p.Tyr134Cys missense_variant 0.67 ethionamide
Rv0565c 657072 p.His133Gln missense_variant 0.67 ethionamide
Rv0565c 657088 p.Asn128Gly missense_variant 0.57 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 0.87 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.93 ethionamide
Rv0565c 657196 p.Asp92Thr missense_variant 0.93 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 0.91 ethionamide
Rv0565c 657207 c.264G>A synonymous_variant 0.92 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 0.92 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.92 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.92 ethionamide Uncertain significance
Rv0565c 657243 c.228C>A synonymous_variant 0.92 ethionamide
Rv0565c 657267 c.202_204delTCGinsAGC synonymous_variant 0.91 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.98 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.96 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.91 ethionamide
Rv0565c 657340 p.Ala44Glu missense_variant 0.69 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 0.71 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.67 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.67 ethionamide
Rv0565c 657560 c.-90G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657563 c.-93T>C upstream_gene_variant 0.92 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 0.94 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.96 ethionamide
Rv0565c 657587 c.-117C>T upstream_gene_variant 0.94 ethionamide
Rv0565c 657590 c.-120G>C upstream_gene_variant 0.95 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 0.96 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.97 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsAT upstream_gene_variant 0.94 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.97 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.97 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.96 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.93 ethionamide
hadA 731687 c.-243G>C upstream_gene_variant 0.95 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 0.95 isoniazid
hadA 731693 c.-237_-236insGTTTGACACCAGAT upstream_gene_variant 0.95 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.95 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.97 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.94 isoniazid
hadA 731738 c.-192G>T upstream_gene_variant 0.95 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.93 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.91 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.92 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 0.93 isoniazid
hadA 731837 c.-93C>T upstream_gene_variant 0.87 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.9 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.86 isoniazid
hadA 731858 c.-72G>A upstream_gene_variant 0.87 isoniazid
hadA 732214 c.285A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
hadA 732223 c.294G>T synonymous_variant 0.86 isoniazid
hadA 732226 c.297G>C synonymous_variant 0.87 isoniazid
hadA 732229 c.300C>T synonymous_variant 0.88 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.92 isoniazid
hadA 732247 c.318C>T synonymous_variant 0.94 isoniazid
hadA 732250 c.321C>G synonymous_variant 0.94 isoniazid
hadA 732263 p.Val112Met missense_variant 0.94 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.91 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.94 isoniazid
hadA 732322 p.Glu131Asp missense_variant 0.94 isoniazid
hadA 732329 c.400_402delCTCinsAT frameshift_variant&missense_variant 0.94 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 0.94 isoniazid
hadA 732361 c.432C>T synonymous_variant 0.94 isoniazid
hadA 732376 c.447T>C synonymous_variant 0.92 isoniazid
hadA 732378 c.449_450insGGA disruptive_inframe_insertion 0.91 isoniazid
hadA 732381 p.Glu151Val missense_variant 0.94 isoniazid
hadA 732391 c.462T>A synonymous_variant 0.94 isoniazid
nusG 734075 c.-179T>G upstream_gene_variant 0.91 rifampicin
nusG 734090 c.-164G>A upstream_gene_variant 0.92 rifampicin
nusG 734093 c.-161A>G upstream_gene_variant 0.92 rifampicin
nusG 734102 c.-152G>T upstream_gene_variant 0.96 rifampicin
nusG 734110 c.-144_-143delAAinsGG upstream_gene_variant 0.96 rifampicin
nusG 734118 c.-136_-134delCTTinsAC upstream_gene_variant 0.96 rifampicin
nusG 734135 c.-119G>A upstream_gene_variant 0.96 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 0.94 rifampicin
nusG 734150 c.-104G>T upstream_gene_variant 0.91 rifampicin
nusG 734337 c.84G>C synonymous_variant 0.67 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.83 rifampicin
nusG 734361 c.108C>T synonymous_variant 0.86 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.88 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.9 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.96 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.96 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.96 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.99 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.99 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.94 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.96 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.96 rifampicin
nusG 734616 c.363C>A synonymous_variant 0.94 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.95 rifampicin
nusG 734631 c.378G>A synonymous_variant 0.96 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.97 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.95 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.94 rifampicin
nusG 734661 c.408A>C synonymous_variant 0.94 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.92 rifampicin
nusG 734670 c.417G>A synonymous_variant 0.92 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.91 rifampicin
nusG 734680 p.Ala143Ser missense_variant 0.9 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.87 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.88 rifampicin
nusG 734712 c.459G>C synonymous_variant 0.87 rifampicin
nusG 734718 c.465G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 0.85 rifampicin
nusG 734722 p.Thr157Ala missense_variant 0.85 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.87 rifampicin
nusG 734733 c.480T>A synonymous_variant 0.87 rifampicin
nusG 734736 c.483C>G synonymous_variant 0.89 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.92 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.92 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.93 rifampicin
nusG 734769 c.516G>A synonymous_variant 0.94 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.93 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.93 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.95 rifampicin
nusG 734793 c.540C>T synonymous_variant 0.95 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.96 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.94 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.92 rifampicin
nusG 734874 c.621G>A synonymous_variant 0.95 rifampicin
nusG 734880 c.627C>T synonymous_variant 0.94 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.93 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.86 rifampicin
nusG 734928 c.675A>G synonymous_variant 0.63 rifampicin
rpoB 759583 c.-224T>G upstream_gene_variant 0.9 rifampicin
rpoB 759587 c.-220T>A upstream_gene_variant 0.9 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 0.94 rifampicin
rpoB 759635 c.-172C>T upstream_gene_variant 0.97 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.98 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoB 759661 c.-146G>C upstream_gene_variant 0.99 rifampicin
rpoB 759670 c.-137C>T upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.97 rifampicin
rpoB 759675 c.-132T>C upstream_gene_variant 0.97 rifampicin
rpoB 759676 c.-131A>G upstream_gene_variant 0.97 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 0.94 rifampicin
rpoB 759715 c.-92_-91delGAinsT upstream_gene_variant 0.89 rifampicin
rpoB 759725 c.-82A>C upstream_gene_variant 0.88 rifampicin
rpoB 759732 c.-75_-74insT upstream_gene_variant 0.84 rifampicin
rpoB 759835 p.Ala10Asp missense_variant 0.93 rifampicin
rpoB 759845 c.39T>C synonymous_variant 0.93 rifampicin
rpoB 759846 p.Ser14Ala missense_variant 0.93 rifampicin
rpoB 759850 p.Pro15Gln missense_variant 0.88 rifampicin
rpoB 759869 c.63C>T synonymous_variant 0.94 rifampicin
rpoB 759872 c.66G>A synonymous_variant 0.94 rifampicin
rpoB 759875 c.69T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 759877 p.Asn24Ser missense_variant 0.94 rifampicin
rpoB 759884 c.78A>G synonymous_variant 0.92 rifampicin
rpoB 759896 c.90A>T synonymous_variant 0.94 rifampicin
rpoB 759899 c.93C>T synonymous_variant 0.95 rifampicin
rpoB 759905 c.99C>T synonymous_variant 0.96 rifampicin
rpoB 759914 c.108T>C synonymous_variant 0.96 rifampicin
rpoB 759920 c.114G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 759929 c.123A>G synonymous_variant 0.94 rifampicin
rpoB 759932 c.126T>G synonymous_variant 0.94 rifampicin
rpoB 759944 c.138A>G synonymous_variant 0.93 rifampicin
rpoB 759945 c.139_141delCTCinsTG frameshift_variant&missense_variant 0.93 rifampicin
rpoB 759956 c.150C>G synonymous_variant 0.96 rifampicin
rpoB 759965 c.159T>C synonymous_variant 0.96 rifampicin
rpoB 759989 c.183G>C synonymous_variant 0.96 rifampicin
rpoB 759991 p.Pro62Gln missense_variant 0.96 rifampicin
rpoB 760059 p.Tyr85Asp missense_variant 1.0 rifampicin
rpoB 760067 c.261G>C synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>A synonymous_variant 1.0 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.97 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.96 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.97 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 0.98 rifampicin
rpoB 760196 c.390C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.99 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.99 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.99 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.97 rifampicin
rpoB 760409 c.603C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 0.97 rifampicin
rpoB 760415 c.609C>G synonymous_variant 0.97 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 0.95 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 0.92 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.94 rifampicin
rpoB 760528 p.Gln241Arg missense_variant 0.94 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.93 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.96 rifampicin Uncertain significance
rpoB 760577 c.771G>A synonymous_variant 0.98 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.97 rifampicin
rpoB 760604 c.798G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 0.98 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>A synonymous_variant 0.96 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760664 c.858G>C synonymous_variant 0.89 rifampicin
rpoB 760670 c.864G>C synonymous_variant 0.88 rifampicin
rpoB 760673 c.867G>A synonymous_variant 0.87 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.73 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760805 c.999G>C synonymous_variant 0.82 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.91 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.98 rifampicin
rpoB 760859 c.1053T>G synonymous_variant 0.99 rifampicin
rpoB 760868 c.1062C>G synonymous_variant 0.99 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.97 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.97 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.93 rifampicin
rpoB 760994 c.1188G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.93 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>A synonymous_variant 0.92 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761066 c.1260G>C synonymous_variant 0.94 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 0.93 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.92 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.93 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.96 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 0.96 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.93 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.94 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 0.94 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.94 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761346 p.Val514Ile missense_variant 0.95 rifampicin
rpoB 761384 c.1578C>G synonymous_variant 0.85 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.92 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 0.91 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.92 rifampicin
rpoB 761438 c.1632G>T synonymous_variant 0.92 rifampicin
rpoB 761441 p.Asp545Glu missense_variant 0.92 rifampicin Uncertain significance
rpoB 761444 c.1638T>C synonymous_variant 0.85 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.88 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 0.92 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.94 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.94 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 0.97 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 0.96 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.97 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 0.97 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.97 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.95 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.95 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.95 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.95 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.94 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 0.95 rifampicin
rpoB 761735 c.1929C>G synonymous_variant 0.91 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.98 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.95 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.95 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.97 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.97 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.95 rifampicin
rpoB 761822 c.2016C>G synonymous_variant 0.93 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.89 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.78 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.77 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 0.77 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 0.81 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.81 rifampicin
rpoB 761876 c.2070C>A synonymous_variant 0.85 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.9 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.9 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.9 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.9 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 0.9 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.91 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.92 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 0.93 rifampicin
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 0.92 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762071 c.2265C>T synonymous_variant 0.96 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.97 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 0.97 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.96 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.98 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 0.99 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 0.99 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.98 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.98 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.98 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>G synonymous_variant 0.98 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.95 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.94 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.91 rifampicin
rpoB 762369 c.2563_2565delTTGinsCT frameshift_variant&synonymous_variant 0.91 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.91 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.92 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.96 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.95 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.95 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.95 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.96 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 0.92 rifampicin
rpoB 762489 p.Val895Gln missense_variant 0.91 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.92 rifampicin
rpoC 762518 c.-852C>G upstream_gene_variant 0.93 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.92 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.93 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.93 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.89 rifampicin
rpoC 762557 c.-813G>C upstream_gene_variant 0.89 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.88 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.88 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.85 rifampicin
rpoC 762599 c.-771T>A upstream_gene_variant 0.74 rifampicin
rpoC 762605 c.-765T>C upstream_gene_variant 0.68 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 0.67 rifampicin
rpoC 762617 c.-753C>G upstream_gene_variant 0.46 rifampicin
rpoC 762710 c.-660G>T upstream_gene_variant 0.81 rifampicin
rpoB 762740 c.2934G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762749 c.-621C>G upstream_gene_variant 0.93 rifampicin
rpoC 762758 c.-612G>A upstream_gene_variant 0.93 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 0.93 rifampicin Uncertain significance
rpoC 762764 c.-606G>A upstream_gene_variant 0.96 rifampicin
rpoC 762765 c.-605C>T upstream_gene_variant 0.96 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 0.97 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 0.96 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762813 c.3007_3009delATGinsGC frameshift_variant&missense_variant 0.93 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 0.96 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>T upstream_gene_variant 0.97 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.98 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 0.97 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.98 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.99 rifampicin
rpoB 763193 c.3387C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.97 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.97 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.92 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.92 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.93 rifampicin Uncertain significance
rpoC 763375 c.6C>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.96 rifampicin
rpoC 763430 c.61A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763435 c.66A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 0.95 rifampicin
rpoC 763561 c.192G>A synonymous_variant 0.93 rifampicin
rpoC 763600 c.231C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.95 rifampicin
rpoC 763618 c.249C>A synonymous_variant 0.96 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 0.95 rifampicin
rpoC 763639 c.270G>A synonymous_variant 0.95 rifampicin
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 0.93 rifampicin
rpoC 763666 c.297G>A synonymous_variant 0.93 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.94 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.94 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.92 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.95 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.96 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.98 rifampicin
rpoC 763771 c.402C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.98 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.97 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763819 c.450G>C synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.98 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.94 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.94 rifampicin
rpoC 763916 p.Glu183Gln missense_variant 0.96 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.98 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.98 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.98 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.99 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.99 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.99 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.97 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.97 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.97 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.97 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.97 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.98 rifampicin
rpoC 764101 c.732C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.99 rifampicin
rpoC 764119 c.750G>A synonymous_variant 0.99 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.98 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 0.95 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.92 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.92 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.92 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.94 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.94 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.95 rifampicin
rpoC 764272 c.903G>T synonymous_variant 0.95 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.94 rifampicin
rpoC 764317 c.948C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>T synonymous_variant 0.93 rifampicin
rpoC 764347 c.978G>C synonymous_variant 0.94 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.92 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>A synonymous_variant 0.85 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.91 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.88 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.88 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.88 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.89 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.96 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.96 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>A synonymous_variant 0.98 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 0.96 rifampicin
rpoC 764536 c.1167G>A synonymous_variant 0.96 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.95 rifampicin
rpoC 764587 c.1218C>G synonymous_variant 0.97 rifampicin
rpoC 764648 c.1279C>A synonymous_variant 0.98 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 0.97 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.98 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764674 c.1305G>A synonymous_variant 0.98 rifampicin
rpoC 764681 c.1312C>T synonymous_variant 0.98 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.96 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>C synonymous_variant 0.97 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 0.96 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.96 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.97 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 0.97 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 0.97 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764918 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.96 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765067 c.1698G>C synonymous_variant 0.87 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.86 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 0.86 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 0.83 rifampicin
rpoC 765088 c.1719G>C synonymous_variant 0.83 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765100 c.1731G>C synonymous_variant 0.8 rifampicin
rpoC 765103 c.1734G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765115 c.1746G>A synonymous_variant 0.8 rifampicin
rpoC 765122 c.1753C>T synonymous_variant 0.79 rifampicin
rpoC 765208 c.1839T>C synonymous_variant 0.77 rifampicin
rpoC 765217 c.1848C>G synonymous_variant 0.82 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 0.85 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 0.87 rifampicin
rpoC 765245 c.1877_1878insGCT disruptive_inframe_insertion 0.83 rifampicin
rpoC 765249 p.Leu627Ser missense_variant 0.78 rifampicin
rpoC 765250 c.1882_1884delAGC conservative_inframe_deletion 0.81 rifampicin
rpoC 765287 c.1918C>T synonymous_variant 0.77 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.74 rifampicin
rpoC 765296 c.1927_1929delCCGinsTT frameshift_variant&missense_variant 0.74 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.7 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>G synonymous_variant 0.53 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.47 rifampicin Uncertain significance
rpoC 765340 p.Gln657His missense_variant 0.65 rifampicin
rpoC 765349 p.Asp660Glu missense_variant 0.75 rifampicin
rpoC 765350 c.1981_1983delGCGinsCC frameshift_variant&missense_variant 0.75 rifampicin
rpoC 765358 p.Met663Ile missense_variant 0.81 rifampicin Uncertain significance
rpoC 765364 p.Glu665Asp missense_variant 0.81 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 0.82 rifampicin
rpoC 765376 c.2007C>G synonymous_variant 0.89 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.89 rifampicin Uncertain significance
rpoC 765395 c.2026C>T synonymous_variant 0.91 rifampicin
rpoC 765405 p.Leu679Pro missense_variant 0.96 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 0.94 rifampicin
rpoC 765430 c.2061G>A synonymous_variant 0.97 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.97 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 0.98 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765526 c.2157C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>A synonymous_variant 0.98 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.98 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.97 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.96 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.95 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 0.95 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 0.95 rifampicin
rpoC 765610 c.2241C>T synonymous_variant 0.94 rifampicin
rpoC 765612 p.His748Arg missense_variant 0.94 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.96 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765676 c.2307G>A synonymous_variant 0.97 rifampicin
rpoC 765688 c.2319G>C synonymous_variant 0.97 rifampicin
rpoC 765689 c.2320C>T synonymous_variant 0.97 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 0.97 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 0.95 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 0.97 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 0.97 rifampicin
rpoC 765757 c.2388C>T synonymous_variant 0.97 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.97 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.97 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.95 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.95 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>A synonymous_variant 0.99 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.98 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.98 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.98 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 0.98 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 0.97 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.96 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 0.93 rifampicin
rpoC 766070 c.2701C>T synonymous_variant 0.89 rifampicin Not assoc w R
rpoC 766082 p.Ala905Gln missense_variant 0.78 rifampicin
rpoC 766089 c.2720_2721delACinsGGGTTGATGGGCAA missense_variant&conservative_inframe_insertion 0.58 rifampicin
rpoC 766092 p.Gly908Val missense_variant 0.58 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.58 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 0.4 rifampicin
rpoC 766249 c.2880C>A synonymous_variant 0.52 rifampicin
rpoC 766255 c.2886G>T synonymous_variant 0.71 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.82 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.86 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.88 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 0.89 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766306 c.2937C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.9 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.9 rifampicin
rpoC 766324 c.2955C>T synonymous_variant 0.94 rifampicin
rpoC 766351 c.2982C>G synonymous_variant 0.98 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.98 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.98 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.99 rifampicin
rpoC 766397 c.3028C>T synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766417 c.3048C>T synonymous_variant 0.99 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.99 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.99 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.97 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.99 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766519 c.3150C>A synonymous_variant 0.98 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.97 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.96 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.96 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.95 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 0.92 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 0.95 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.95 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.92 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.93 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.95 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 0.96 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.99 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.96 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.96 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.96 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.98 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.96 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 0.96 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.95 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.95 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.95 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.95 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.96 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766795 c.3426C>T synonymous_variant 0.99 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.99 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.98 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.98 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.98 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766918 c.3549C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.97 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.97 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.95 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.98 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>T synonymous_variant 0.93 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.93 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.93 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.94 rifampicin
rpoC 767206 c.3837C>A synonymous_variant 0.93 rifampicin
rpoC 767209 c.3840T>G synonymous_variant 0.93 rifampicin
rpoC 767212 c.3843G>C synonymous_variant 0.92 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.9 rifampicin
rpoC 767275 c.3906T>A synonymous_variant 0.89 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.89 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.89 rifampicin
rpoC 767287 c.3918G>A synonymous_variant 0.89 rifampicin
rpoC 767317 c.3948C>G synonymous_variant 0.7 rifampicin
rpsL 781571 c.12C>T synonymous_variant 0.88 streptomycin
rpsL 781586 c.27C>A synonymous_variant 0.94 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.95 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.97 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.93 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.95 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.94 streptomycin
rpsL 781664 c.105C>T synonymous_variant 0.94 streptomycin
rpsL 781667 c.108C>G synonymous_variant 0.94 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.96 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.96 streptomycin
rpsL 781721 c.162C>G synonymous_variant 0.96 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.96 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.97 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.96 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.92 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.93 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.91 streptomycin
rpsL 781847 c.288G>A synonymous_variant 0.92 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.91 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.92 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.92 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.93 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.93 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.91 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.93 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.95 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.95 streptomycin Uncertain significance
rplC 800209 c.-600C>T upstream_gene_variant 0.95 linezolid
rplC 800224 c.-585G>C upstream_gene_variant 0.93 linezolid
rplC 800225 c.-584T>C upstream_gene_variant 0.93 linezolid
rplC 800237 c.-572T>C upstream_gene_variant 0.92 linezolid
rplC 800244 c.-565A>G upstream_gene_variant 0.92 linezolid
rplC 800267 c.-542T>C upstream_gene_variant 0.91 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 0.91 linezolid
rplC 800278 c.-531A>G upstream_gene_variant 0.89 linezolid
rplC 800285 c.-524_-523insC upstream_gene_variant 0.92 linezolid
rplC 800295 c.-513_-502delCTTGAAATTGAT upstream_gene_variant 0.71 linezolid
rplC 800311 c.-498delGinsCT upstream_gene_variant 0.71 linezolid
rplC 800321 c.-488T>C upstream_gene_variant 0.79 linezolid
rplC 800341 c.-468G>C upstream_gene_variant 0.82 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.99 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.99 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.99 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.98 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.98 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 0.98 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.98 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.98 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.95 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.97 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.94 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.94 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.94 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.94 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.94 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.95 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.97 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.96 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.96 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 0.94 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 0.94 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 0.95 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 0.95 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 0.95 linezolid
rplC 800817 c.9A>C synonymous_variant 0.95 linezolid
rplC 800844 c.36T>C synonymous_variant 0.97 linezolid
rplC 800865 c.57A>G synonymous_variant 0.96 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.96 linezolid
rplC 800877 c.69A>C synonymous_variant 0.98 linezolid
rplC 800907 c.99C>G synonymous_variant 0.96 linezolid
rplC 800913 c.105G>C synonymous_variant 0.96 linezolid
rplC 800916 c.108A>T synonymous_variant 0.96 linezolid
rplC 800922 c.114C>G synonymous_variant 0.96 linezolid
rplC 800934 c.126C>G synonymous_variant 0.96 linezolid
rplC 800937 c.129A>G synonymous_variant 0.96 linezolid
rplC 800946 c.138T>G synonymous_variant 0.95 linezolid
rplC 800949 c.141T>C synonymous_variant 0.95 linezolid
rplC 800955 c.147C>G synonymous_variant 0.94 linezolid
rplC 800958 c.150G>A synonymous_variant 0.94 linezolid
rplC 800970 c.162T>C synonymous_variant 0.92 linezolid Not assoc w R - Interim
rplC 800976 c.168G>A synonymous_variant 0.94 linezolid
rplC 800982 c.174C>T synonymous_variant 0.93 linezolid
rplC 801117 c.309G>C synonymous_variant 0.8 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801144 c.336C>G synonymous_variant 0.94 linezolid
rplC 801147 c.339T>C synonymous_variant 0.96 linezolid
rplC 801153 c.345G>C synonymous_variant 0.96 linezolid
rplC 801174 c.366T>C synonymous_variant 0.95 linezolid
rplC 801201 c.393C>T synonymous_variant 0.96 linezolid
rplC 801210 c.402T>C synonymous_variant 0.96 linezolid
rplC 801216 c.408C>A synonymous_variant 0.96 linezolid
rplC 801219 c.411C>T synonymous_variant 0.96 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.97 linezolid
rplC 801246 c.438C>G synonymous_variant 0.98 linezolid
rplC 801252 c.444G>C synonymous_variant 0.98 linezolid
rplC 801267 c.459A>T synonymous_variant 0.96 linezolid
rplC 801276 c.468G>C synonymous_variant 0.97 linezolid
rplC 801297 c.489C>T synonymous_variant 0.96 linezolid Not assoc w R - Interim
rplC 801312 c.504G>C synonymous_variant 0.96 linezolid
rplC 801339 c.531T>G synonymous_variant 0.96 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.96 linezolid
rplC 801348 c.540T>G synonymous_variant 0.96 linezolid
rplC 801357 c.549T>C synonymous_variant 0.95 linezolid
rplC 801372 c.564G>A synonymous_variant 0.97 linezolid
rplC 801385 c.577C>T synonymous_variant 0.96 linezolid
rplC 801396 c.588T>C synonymous_variant 0.96 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801417 c.609T>C synonymous_variant 0.95 linezolid
rplC 801423 c.615G>C synonymous_variant 0.95 linezolid
rplC 801426 c.618C>G synonymous_variant 0.95 linezolid
rplC 801438 c.630T>C synonymous_variant 0.82 linezolid
rplC 801447 c.639A>G synonymous_variant 0.8 linezolid
Rv1129c 1253450 p.Ser362Asn missense_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253461 c.1074G>C synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253464 c.1069_1071delAGCinsTCT synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253476 c.1059G>A synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253482 c.1053G>C synonymous_variant 0.69 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253491 c.1044A>C synonymous_variant 0.82 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253494 c.1041G>A synonymous_variant 0.82 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253509 c.1026C>A synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253512 p.Lys341Ser missense_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
fbiC 1303431 c.501T>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303467 c.537C>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303479 c.549G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303591 c.661C>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303632 c.702T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303768 p.Ser280Ala missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303956 p.Glu342Asp missense_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>T synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304055 p.Asp375Glu missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 0.73 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304059 c.1129C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304091 c.1161C>T synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304112 c.1182G>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304120 p.Lys397Arg missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304124 c.1194C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304164 p.Gly412Arg missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304181 c.1251G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304217 p.Asn429Lys missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304502 c.1572G>A synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304511 c.1581C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304598 c.1668C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304649 c.1719C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304679 c.1749G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304715 c.1785G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304809 p.Ser627Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.91 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305001 p.Ile691Val missense_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1305027 c.2097G>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1305036 c.2106G>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1305051 c.2121G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305088 p.Val720Ile missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305162 c.2232C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305165 c.2235G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305192 c.2262C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305219 p.His763Gln missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>A synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305375 c.2445C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
sigE 1364796 c.384G>A synonymous_variant 0.97 pyrazinamide
sigE 1364802 c.390C>G synonymous_variant 0.95 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.94 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 0.94 pyrazinamide Uncertain significance
sigE 1364839 c.427T>C synonymous_variant 0.96 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 0.96 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.96 pyrazinamide
sigE 1364866 c.454_456delGCTinsAC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
sigE 1364889 c.477A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 0.97 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
sigE 1364919 c.507T>C synonymous_variant 0.97 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.97 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.96 pyrazinamide
sigE 1364955 c.543G>T synonymous_variant 0.95 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.94 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
sigE 1364967 c.555C>T synonymous_variant 0.93 pyrazinamide
sigE 1364968 c.556C>T synonymous_variant 0.93 pyrazinamide
sigE 1364980 c.568_570delTTGinsCC frameshift_variant&missense_variant 0.93 pyrazinamide Uncertain significance
sigE 1364984 p.Ala191Asp missense_variant 0.93 pyrazinamide
Rv1258c 1406270 c.1071C>T synonymous_variant 0.95 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406291 c.1050G>A synonymous_variant 0.95 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406297 c.1044A>G synonymous_variant 0.95 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406314 p.His343Tyr missense_variant 0.93 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406315 p.Gln342His missense_variant 0.93 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406318 c.1021_1023delGCAinsCG frameshift_variant&synonymous_variant 0.93 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406327 c.1014G>C synonymous_variant 0.87 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406330 c.1011G>A synonymous_variant 0.87 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406333 p.Ile336Met missense_variant 0.87 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406345 c.996T>C synonymous_variant 0.81 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406351 c.990G>C synonymous_variant 0.76 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406360 c.981C>G synonymous_variant 0.64 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406553 p.Ala263Val missense_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406556 p.Trp262Ser missense_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406558 c.783T>C synonymous_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406567 p.Val258Ala missense_variant 0.73 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406576 p.Gln255His missense_variant 0.73 streptomycin
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406580 p.His254Arg missense_variant 0.73 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406587 p.Thr252Ala missense_variant 0.71 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406594 c.747A>G synonymous_variant 0.71 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406597 c.744G>C synonymous_variant 0.71 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406612 c.729G>A synonymous_variant 0.71 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406636 c.705C>G synonymous_variant 0.67 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407131 c.210G>C synonymous_variant 0.77 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407167 c.172_174delGCCinsTG frameshift_variant&missense_variant 0.94 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1407175 c.166T>C synonymous_variant 0.92 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407185 p.Met52Thr missense_variant 0.92 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407194 c.145_147delAGTinsGC frameshift_variant&synonymous_variant 0.92 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1407200 c.141G>T synonymous_variant 0.92 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407203 c.138C>T synonymous_variant 0.92 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407209 c.132C>G synonymous_variant 0.9 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407218 c.123T>G synonymous_variant 0.89 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407227 c.114G>A synonymous_variant 0.88 streptomycin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
pyrazinamide
Rv1258c 1407423 c.-83G>C upstream_gene_variant 0.57 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407443 c.-103C>A upstream_gene_variant 0.79 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407455 c.-115C>T upstream_gene_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407459 c.-119T>C upstream_gene_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407464 c.-124G>A upstream_gene_variant 0.83 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407470 c.-130T>G upstream_gene_variant 0.83 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407473 c.-133C>A upstream_gene_variant 0.82 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407479 c.-139A>G upstream_gene_variant 0.83 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407480 c.-140A>T upstream_gene_variant 0.83 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407491 c.-151T>C upstream_gene_variant 0.78 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407494 c.-154A>G upstream_gene_variant 0.78 streptomycin
isoniazid
pyrazinamide
Rv1258c 1407524 c.-184A>C upstream_gene_variant 0.74 streptomycin
isoniazid
pyrazinamide
embR 1416826 c.522T>C synonymous_variant 0.75 ethambutol
embR 1416832 c.516T>C synonymous_variant 0.75 ethambutol
embR 1416837 p.Val171Ile missense_variant 0.75 ethambutol
embR 1416844 c.504A>G synonymous_variant 0.75 ethambutol
embR 1416847 c.501A>G synonymous_variant 0.75 ethambutol
embR 1416850 c.498G>C synonymous_variant 0.75 ethambutol
embR 1416856 c.492G>C synonymous_variant 0.69 ethambutol
embR 1416862 c.486T>C synonymous_variant 0.69 ethambutol
embR 1416865 c.481_483delCCCinsGG frameshift_variant&missense_variant 0.69 ethambutol Uncertain significance
embR 1416868 c.478_480delGAAinsAC frameshift_variant&missense_variant 0.69 ethambutol Uncertain significance
embR 1417879 c.-532A>G upstream_gene_variant 0.6 ethambutol
embR 1417882 c.-535A>G upstream_gene_variant 0.6 ethambutol
embR 1417892 c.-545C>G upstream_gene_variant 0.6 ethambutol
atpE 1460879 c.-166C>T upstream_gene_variant 0.69 bedaquiline
atpE 1460895 c.-150_-148delGCAinsTG upstream_gene_variant 0.68 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.72 bedaquiline
atpE 1460904 c.-141C>T upstream_gene_variant 0.81 bedaquiline
atpE 1460918 c.-127A>C upstream_gene_variant 0.75 bedaquiline
atpE 1460927 c.-118C>G upstream_gene_variant 0.75 bedaquiline
atpE 1460936 c.-109T>C upstream_gene_variant 0.75 bedaquiline
atpE 1460939 c.-106G>T upstream_gene_variant 0.75 bedaquiline
atpE 1460948 c.-97A>G upstream_gene_variant 0.69 bedaquiline
atpE 1460951 c.-94T>C upstream_gene_variant 0.64 bedaquiline
atpE 1460952 c.-93_-91delTTGinsCC upstream_gene_variant 0.64 bedaquiline
atpE 1461025 c.-20C>T upstream_gene_variant 0.57 bedaquiline
atpE 1461041 c.-4_-2delGGAinsAAGG upstream_gene_variant 0.72 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.92 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.93 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 0.94 bedaquiline
atpE 1461161 c.117C>T synonymous_variant 0.96 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 0.95 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.96 bedaquiline
atpE 1461185 c.141G>A synonymous_variant 0.96 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.97 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.95 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.94 bedaquiline
atpE 1461230 c.186G>T synonymous_variant 0.94 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.92 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.88 bedaquiline
atpE 1461275 c.231T>C synonymous_variant 0.84 bedaquiline
atpE 1461278 c.234A>G synonymous_variant 0.82 bedaquiline
rrs 1471935 n.90T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471984 n.139T>A non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.84 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473403 n.-255_-249delCCCAACTinsATCCCAACA upstream_gene_variant 0.83 capreomycin
linezolid
rrl 1473410 n.-248G>A upstream_gene_variant 0.79 capreomycin
linezolid
rrl 1473417 n.-241C>T upstream_gene_variant 0.79 capreomycin
linezolid
rrl 1473419 n.-239T>C upstream_gene_variant 0.79 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.82 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.83 capreomycin
linezolid
rrl 1473449 n.-209G>A upstream_gene_variant 0.72 capreomycin
linezolid
rrl 1473453 n.-205G>A upstream_gene_variant 0.72 capreomycin
linezolid
rrl 1473493 n.-165G>A upstream_gene_variant 0.75 capreomycin
linezolid
rrl 1473517 n.-141A>G upstream_gene_variant 0.7 capreomycin
linezolid
rrl 1473519 n.-139_-138insC upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473525 n.-133C>G upstream_gene_variant 0.67 capreomycin
linezolid
rrl 1473528 n.-130_-129delGTinsA upstream_gene_variant 0.71 capreomycin
linezolid
rrl 1473541 n.-117G>A upstream_gene_variant 0.71 capreomycin
linezolid
rrl 1473542 n.-116C>T upstream_gene_variant 0.71 capreomycin
linezolid
rrl 1473571 n.-87C>T upstream_gene_variant 0.84 capreomycin
linezolid
rrl 1473592 n.-66_-65insA upstream_gene_variant 0.86 capreomycin
linezolid
rrl 1473600 n.-58A>G upstream_gene_variant 0.89 capreomycin
linezolid
rrl 1473603 n.-55C>T upstream_gene_variant 0.89 capreomycin
linezolid
rrl 1473607 n.-50_-49delGG upstream_gene_variant 0.94 capreomycin
linezolid
rrl 1473613 n.-45G>C upstream_gene_variant 0.94 capreomycin
linezolid
rrl 1473614 n.-44C>G upstream_gene_variant 0.94 capreomycin
linezolid
rrl 1473618 n.-40G>A upstream_gene_variant 0.89 capreomycin
linezolid
rrl 1473626 n.-32_-31insT upstream_gene_variant 0.91 capreomycin
linezolid
rrl 1473635 n.-23_-22insTTT upstream_gene_variant 0.84 capreomycin
linezolid
rrl 1473648 n.-9_-7delTTG upstream_gene_variant 0.77 capreomycin
linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473981 n.324delGinsTC non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474285 n.630_631delTC non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474293 n.636_649delTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475273 n.1616T>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475290 n.1633A>G non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476759 n.3102T>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
inhA 1673475 c.-727A>C upstream_gene_variant 0.81 ethionamide
isoniazid
inhA 1673493 c.-709C>T upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673499 c.-703T>C upstream_gene_variant 0.95 ethionamide
isoniazid Uncertain significance
inhA 1673505 c.-697A>T upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673517 c.-685G>A upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673568 c.-634C>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673589 c.-613A>C upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.91 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 0.93 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 0.93 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.87 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.87 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673679 c.-523T>G upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673682 c.-520G>C upstream_gene_variant 0.89 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.9 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsGC frameshift_variant&missense_variant 0.91 ethionamide
isoniazid
inhA 1673715 c.-487C>T upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 0.88 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.89 ethionamide
isoniazid
inhA 1673736 c.-466G>A upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673745 c.-457G>A upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.88 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.88 ethionamide
isoniazid
fabG1 1673767 p.Asn110Asp missense_variant 0.85 ethionamide
isoniazid
inhA 1673784 c.-418G>A upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673862 c.-340C>G upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673871 c.-331C>T upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673916 c.-286A>T upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673919 c.-283G>C upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673925 c.-277C>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673946 c.-256C>A upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.93 ethionamide
isoniazid
fabG1 1673960 p.Ala174Val missense_variant 0.93 ethionamide
isoniazid
inhA 1673970 c.-232C>G upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673982 c.-220G>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 0.87 ethionamide
isoniazid
inhA 1673991 c.-211C>G upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1674015 c.-187C>A upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1674018 c.-184G>C upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1674037 p.Gln200Glu missense_variant 0.9 ethionamide
isoniazid
inhA 1674045 c.-157G>A upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1674079 c.640_642delCCCinsGT frameshift_variant&missense_variant 0.94 ethionamide
isoniazid
inhA 1674105 c.-97C>T upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1674108 c.-94C>T upstream_gene_variant 0.93 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674111 c.-91G>A upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1674117 c.-85C>G upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1674156 c.-46C>T upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1674258 c.57G>C synonymous_variant 0.43 ethionamide
isoniazid
inhA 1674273 c.72C>T synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674279 c.78A>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674285 c.84A>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674315 c.114C>G synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674321 c.120G>T synonymous_variant 0.7 ethionamide
isoniazid
inhA 1674331 c.130C>T synonymous_variant 0.75 ethionamide
isoniazid
inhA 1674462 c.261G>A synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674472 p.Val91Leu missense_variant 0.76 ethionamide
isoniazid
inhA 1674477 c.276G>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674501 c.300G>A synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 0.91 ethionamide
isoniazid
inhA 1674513 c.312C>G synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.95 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674594 c.393C>A synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674601 c.400C>T synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674609 c.408G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 0.93 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674675 c.474C>T synonymous_variant 0.99 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.99 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 0.99 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.99 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674762 c.561T>C synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674799 p.Ser200Ala missense_variant 0.96 ethionamide
isoniazid
inhA 1674804 c.603G>A synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.99 ethionamide
isoniazid
inhA 1674852 c.651G>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674882 c.681G>C synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674885 c.684C>T synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674903 c.702T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.96 ethionamide
isoniazid
inhA 1674912 c.711G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674927 c.726G>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674933 c.732G>A synonymous_variant 0.89 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674942 c.741T>G synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674945 p.Asp248Glu missense_variant 0.92 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674966 c.765T>G synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674977 p.Tyr259Phe missense_variant 0.93 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674999 c.798C>T synonymous_variant 0.98 ethionamide
isoniazid
inhA 1675002 c.801A>G synonymous_variant 0.98 ethionamide
isoniazid
rpsA 1833256 c.-286C>G upstream_gene_variant 0.91 pyrazinamide
rpsA 1833262 c.-280T>A upstream_gene_variant 0.9 pyrazinamide
rpsA 1833271 c.-271G>A upstream_gene_variant 0.89 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 0.86 pyrazinamide
rpsA 1833295 c.-247C>G upstream_gene_variant 0.88 pyrazinamide
rpsA 1833298 c.-244G>A upstream_gene_variant 0.88 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.87 pyrazinamide
rpsA 1833317 c.-225_-223delCTCinsTG upstream_gene_variant 0.81 pyrazinamide
rpsA 1833325 c.-217C>T upstream_gene_variant 0.81 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 0.98 pyrazinamide
rpsA 1833593 c.52_54delTCTinsAC frameshift_variant&missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1833604 c.63C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833610 c.69C>A synonymous_variant 0.98 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.97 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833718 c.177C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833754 c.213G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834024 c.483G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 0.96 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834148 c.607C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834154 c.613_615delAACinsCA frameshift_variant&missense_variant 0.89 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.91 pyrazinamide
rpsA 1834174 c.633C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.96 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 0.95 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.95 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 0.95 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834615 c.1074C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.73 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 0.96 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.94 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.93 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 0.91 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.91 linezolid
tsnR 1853408 c.-198C>T upstream_gene_variant 0.9 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.87 linezolid
tsnR 1853426 c.-180G>A upstream_gene_variant 0.85 linezolid
tsnR 1853429 c.-177G>T upstream_gene_variant 0.84 linezolid
tsnR 1854004 c.399T>G synonymous_variant 0.86 linezolid
tsnR 1854013 c.408G>C synonymous_variant 0.8 linezolid
tsnR 1854022 c.417C>T synonymous_variant 0.8 linezolid
tsnR 1854028 c.423G>A synonymous_variant 0.8 linezolid
tsnR 1854030 p.Arg142His missense_variant 0.86 linezolid
tsnR 1854043 c.438A>G synonymous_variant 0.85 linezolid
tlyA 1917893 c.-47G>C upstream_gene_variant 0.79 capreomycin
tlyA 1917903 c.-37_-35delGCCinsCGG upstream_gene_variant 0.81 capreomycin
tlyA 1917929 c.-11T>C upstream_gene_variant 0.84 capreomycin
tlyA 1917934 c.-6T>G upstream_gene_variant 0.86 capreomycin
tlyA 1917937 c.-3G>A upstream_gene_variant 0.86 capreomycin
tlyA 1917938 c.-2G>A upstream_gene_variant 0.86 capreomycin
tlyA 1917948 c.9A>G synonymous_variant 0.91 capreomycin
tlyA 1917965 p.Ala9Val missense_variant 0.95 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.93 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.92 capreomycin
tlyA 1917987 c.48G>C synonymous_variant 0.92 capreomycin
tlyA 1917996 c.57A>C synonymous_variant 0.93 capreomycin
tlyA 1918002 p.Gln21His missense_variant 0.93 capreomycin
tlyA 1918008 c.69C>T synonymous_variant 0.92 capreomycin
tlyA 1918014 c.75G>A synonymous_variant 0.91 capreomycin
tlyA 1918022 p.Gly28Glu missense_variant 0.91 capreomycin
tlyA 1918047 c.108G>C synonymous_variant 0.88 capreomycin
tlyA 1918055 p.Ala39Val missense_variant 0.81 capreomycin
tlyA 1918068 c.129C>G synonymous_variant 0.62 capreomycin
bacA 2062995 c.1734C>G synonymous_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2062998 c.1731T>C synonymous_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063001 c.1728A>G synonymous_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063013 c.1716C>A synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063016 c.1713G>C synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063019 c.1710G>A synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063043 c.1686T>C synonymous_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063046 c.1683T>C synonymous_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063055 c.1674T>C synonymous_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063058 c.1671A>G synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063067 c.1662T>C synonymous_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063076 c.1653C>G synonymous_variant 0.81 streptomycin Not assoc w R - Interim
kanamycin
capreomycin
amikacin
bacA 2063103 p.Asp542Glu missense_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063106 c.1623G>C synonymous_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063205 c.1524T>G synonymous_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063211 c.1518G>T synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063214 c.1515G>C synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063238 c.1491G>C synonymous_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063253 c.1476G>A synonymous_variant 0.96 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
bacA 2063259 p.Glu490Asp missense_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063262 c.1467C>T synonymous_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063266 p.Gly488Asp missense_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063271 c.1458G>T synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063275 p.His485Arg missense_variant 0.92 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin
bacA 2063280 c.1449C>A synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063289 c.1440A>C synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063295 c.1434C>G synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063301 c.1428G>A synonymous_variant 0.88 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
bacA 2063307 c.1422G>C synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063490 c.1239C>G synonymous_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063496 c.1233C>T synonymous_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063499 c.1230A>G synonymous_variant 0.8 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063514 c.1215C>T synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063520 c.1209G>C synonymous_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063523 c.1204_1206delCATinsTC frameshift_variant&missense_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063529 c.1200A>G synonymous_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063538 c.1191A>G synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063541 c.1188A>G synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063550 c.1179C>G synonymous_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063553 c.1176G>C synonymous_variant 0.84 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063556 c.1173T>C synonymous_variant 0.84 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063601 c.1128C>T synonymous_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063658 c.1071A>G synonymous_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063667 c.1062G>A synonymous_variant 0.94 streptomycin
kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
bacA 2063676 c.1053C>G synonymous_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063697 c.1032A>G synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063703 c.1026C>T synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063715 c.1014T>C synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063724 c.1005T>C synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063730 c.999A>T synonymous_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063742 c.987G>C synonymous_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063751 c.978C>A synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063754 c.975T>C synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063760 c.969T>C synonymous_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063826 c.903T>C synonymous_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063832 c.897G>C synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063835 c.894G>A synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063847 c.882C>A synonymous_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063850 c.877_879delCTAinsTG frameshift_variant&synonymous_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063853 c.876G>C synonymous_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063856 c.873T>G synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063868 c.861T>G synonymous_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063892 c.837T>C synonymous_variant 0.85 streptomycin Not assoc w R - Interim
kanamycin
capreomycin
amikacin
bacA 2063895 c.834C>A synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063901 c.828C>T synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063916 c.813C>A synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063919 c.810G>T synonymous_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063930 p.Ile267Val missense_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063934 c.795G>C synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063949 c.780G>T synonymous_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063954 p.Phe259Leu missense_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064018 c.711C>A synonymous_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064021 c.708G>C synonymous_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064027 c.702T>C synonymous_variant 0.59 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064042 c.687A>C synonymous_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064048 c.681T>C synonymous_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064060 c.669T>C synonymous_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064063 c.666C>T synonymous_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064069 c.660G>A synonymous_variant 0.74 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064096 p.Ala211Gly missense_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064099 c.630G>C synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064111 c.618C>G synonymous_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064114 c.615T>G synonymous_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064117 c.612T>C synonymous_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064120 c.609G>C synonymous_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064123 c.606T>G synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064129 c.600C>T synonymous_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064132 p.Ala199Val missense_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064135 c.594G>A synonymous_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064150 c.579T>C synonymous_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064155 p.Val192Ile missense_variant 0.95 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
bacA 2064165 c.564T>C synonymous_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064192 c.537A>G synonymous_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064207 c.522C>T synonymous_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064210 c.519A>G synonymous_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064219 c.510C>G synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064222 c.507G>A synonymous_variant 0.94 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
bacA 2064240 c.487_489delCAAinsAG frameshift_variant&synonymous_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064243 c.486A>C synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064254 p.His159Asp missense_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064258 c.471A>G synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064264 c.465C>G synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064269 c.460A>C synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064296 c.433T>C synonymous_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064297 c.432C>T synonymous_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064312 c.417C>G synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064319 p.Thr137Val missense_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064327 c.400_402delCTGinsAA frameshift_variant&missense_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064339 c.388_390delGTGinsAC frameshift_variant&missense_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064357 c.372G>A synonymous_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064369 c.360A>G synonymous_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064373 p.Arg119Gln missense_variant 0.69 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064984 c.-256A>G upstream_gene_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2065002 c.-274C>G upstream_gene_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101744 p.Asp433Glu missense_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>G synonymous_variant 0.74 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 0.74 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.74 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>C synonymous_variant 0.74 ethionamide
delamanid
isoniazid
ndh 2101795 c.1248G>C synonymous_variant 0.75 ethionamide
delamanid
isoniazid
ndh 2101873 c.1168_1170delTTTinsCC frameshift_variant&missense_variant 0.79 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101888 c.1155T>G synonymous_variant 0.85 ethionamide
delamanid
isoniazid
ndh 2101891 c.1152C>G synonymous_variant 0.85 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101899 p.Ile382Val missense_variant 0.87 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 0.85 ethionamide
delamanid
isoniazid
ndh 2101920 c.1123A>C synonymous_variant 0.87 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2101936 c.1107G>C synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>C synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101963 c.1080G>A synonymous_variant 0.92 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101971 p.Glu358Gln missense_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101972 c.1069_1071delGCGinsAT frameshift_variant&missense_variant 0.92 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101980 p.Asn355Asp missense_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101984 c.1059C>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101999 c.1044G>A synonymous_variant 0.91 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102010 p.Ser345Gly missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102015 p.Val343Ala missense_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102020 c.1023A>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102023 c.1020G>C synonymous_variant 0.91 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102026 c.1017G>T synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2102212 c.831G>C synonymous_variant 0.79 ethionamide
delamanid
isoniazid
ndh 2102218 c.825C>G synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2102227 p.Ala272Gln missense_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2102247 p.Val266Ile missense_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102263 c.780G>A synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102287 c.756C>A synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102302 c.741G>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102332 c.709_711delCAGinsGA frameshift_variant&missense_variant 0.86 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102337 c.706T>C synonymous_variant 0.86 ethionamide Not assoc w R - Interim
delamanid
isoniazid
ndh 2102344 c.699T>C synonymous_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2102350 c.693G>C synonymous_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2102617 c.426C>T synonymous_variant 0.53 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102626 c.417G>A synonymous_variant 0.79 ethionamide
delamanid
isoniazid
ndh 2102635 c.408C>G synonymous_variant 0.87 ethionamide
delamanid
isoniazid
ndh 2102638 c.405A>G synonymous_variant 0.87 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102653 c.390T>C synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102668 c.375T>C synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>C synonymous_variant 0.89 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102677 c.366C>G synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>G synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>G synonymous_variant 0.81 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 0.77 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>C synonymous_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102878 c.165G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102902 c.141C>T synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102908 c.135C>T synonymous_variant 0.95 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102911 c.132G>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102919 c.124C>T synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102932 c.111C>T synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102938 c.105G>T synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102962 c.81A>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102965 c.78G>C synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2102974 c.69G>A synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102989 c.54G>C synonymous_variant 0.84 ethionamide
delamanid
isoniazid
ndh 2102992 c.51T>C synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2103008 p.Pro12Arg missense_variant 0.79 ethionamide
delamanid
isoniazid
ndh 2103012 p.Pro11Thr missense_variant 0.77 ethionamide
delamanid
isoniazid
ndh 2103015 p.Gln10Glu missense_variant 0.78 ethionamide
delamanid
isoniazid
ndh 2103016 c.27G>T synonymous_variant 0.78 ethionamide
delamanid
isoniazid
ndh 2103025 p.Glu6Asp missense_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2103029 p.Gln5Pro missense_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2103037 c.6T>C synonymous_variant 0.65 ethionamide
delamanid
isoniazid
katG 2155032 c.1080T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
katG 2155047 c.1065C>T synonymous_variant 0.71 isoniazid
katG 2155054 p.Tyr353Phe missense_variant 0.71 isoniazid
katG 2155056 c.1056A>G synonymous_variant 0.71 isoniazid
katG 2155062 c.1050T>C synonymous_variant 0.71 isoniazid
katG 2155065 c.1047C>A synonymous_variant 0.71 isoniazid Not assoc w R - Interim
katG 2155068 c.1044T>C synonymous_variant 0.71 isoniazid
katG 2155071 c.1041T>A synonymous_variant 0.71 isoniazid
katG 2155080 c.1032G>C synonymous_variant 0.71 isoniazid
katG 2155581 c.531C>A synonymous_variant 0.83 isoniazid
katG 2155596 c.516G>C synonymous_variant 0.88 isoniazid
katG 2155600 p.Cys171Val missense_variant 0.88 isoniazid
katG 2155617 c.495T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
katG 2155632 c.480A>C synonymous_variant 0.96 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.96 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.97 isoniazid Uncertain significance
katG 2155649 p.Tyr155His missense_variant 0.98 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.95 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.94 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.94 isoniazid
katG 2155716 c.396T>C synonymous_variant 0.97 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.96 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.96 isoniazid
kasA 2517956 c.-159G>A upstream_gene_variant 0.96 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.95 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.93 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.91 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.91 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.88 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.91 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.91 isoniazid
kasA 2518046 c.-69C>G upstream_gene_variant 0.91 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.89 isoniazid
kasA 2518053 c.-62_-60delATTinsCC upstream_gene_variant 0.89 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 0.83 isoniazid
kasA 2518076 c.-39C>T upstream_gene_variant 0.83 isoniazid
kasA 2518088 c.-27T>C upstream_gene_variant 0.67 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.8 isoniazid
kasA 2518187 p.Ile25Val missense_variant 0.91 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.94 isoniazid
kasA 2518252 c.138C>T synonymous_variant 0.94 isoniazid
kasA 2518279 c.165T>C synonymous_variant 0.92 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.92 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.91 isoniazid
kasA 2518300 c.186T>C synonymous_variant 0.91 isoniazid
kasA 2518312 c.198T>C synonymous_variant 0.93 isoniazid
kasA 2518318 c.204C>G synonymous_variant 0.92 isoniazid
kasA 2518323 p.Ser70Asn missense_variant 0.93 isoniazid
kasA 2518334 c.220_222delCGAinsAG frameshift_variant&synonymous_variant 0.92 isoniazid
kasA 2518339 c.225C>G synonymous_variant 0.92 isoniazid
kasA 2518348 c.234A>G synonymous_variant 0.96 isoniazid
kasA 2518360 c.246C>T synonymous_variant 0.94 isoniazid
kasA 2518374 p.Gly87Ala missense_variant 1.0 isoniazid
kasA 2518379 c.265T>C synonymous_variant 1.0 isoniazid
kasA 2518384 c.270G>C synonymous_variant 1.0 isoniazid
kasA 2518385 p.Gly91Ser missense_variant 1.0 isoniazid
kasA 2518393 p.Gln93His missense_variant 0.97 isoniazid
kasA 2518396 c.282A>C synonymous_variant 0.97 isoniazid
kasA 2518408 c.294C>G synonymous_variant 0.94 isoniazid
kasA 2518417 c.303G>C synonymous_variant 0.92 isoniazid
kasA 2518429 c.315A>G synonymous_variant 0.91 isoniazid
kasA 2518439 p.Ala109Thr missense_variant 0.88 isoniazid
kasA 2518444 c.330T>C synonymous_variant 0.88 isoniazid
kasA 2518447 c.333T>G synonymous_variant 0.88 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.91 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.88 isoniazid
kasA 2518468 c.354A>G synonymous_variant 0.89 isoniazid
kasA 2518471 c.357C>G synonymous_variant 0.89 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.91 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.92 isoniazid
kasA 2518492 c.378C>T synonymous_variant 0.93 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.94 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.94 isoniazid
kasA 2518513 c.399C>G synonymous_variant 0.97 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.95 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.96 isoniazid
kasA 2518537 c.423C>G synonymous_variant 0.95 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.95 isoniazid
kasA 2518567 c.453G>T synonymous_variant 0.93 isoniazid
kasA 2518573 c.459G>C synonymous_variant 0.93 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.92 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.93 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.91 isoniazid
kasA 2518618 c.504G>C synonymous_variant 0.92 isoniazid
kasA 2518633 c.519G>C synonymous_variant 0.91 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.91 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.91 isoniazid
kasA 2518648 c.534C>T synonymous_variant 0.91 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.94 isoniazid
kasA 2518681 c.567C>T synonymous_variant 0.94 isoniazid
kasA 2518684 c.570C>A synonymous_variant 0.94 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.95 isoniazid
kasA 2518714 c.600A>T synonymous_variant 0.95 isoniazid
kasA 2518735 c.621C>A synonymous_variant 0.95 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.96 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.96 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.96 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.97 isoniazid
kasA 2518789 c.675G>T synonymous_variant 0.97 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.97 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.98 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.97 isoniazid
kasA 2518822 c.708C>T synonymous_variant 0.95 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.94 isoniazid
kasA 2518855 c.741C>G synonymous_variant 0.94 isoniazid
kasA 2518856 p.Ile248Leu missense_variant 0.95 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.92 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.92 isoniazid
kasA 2518894 c.780G>A synonymous_variant 0.91 isoniazid
kasA 2518903 c.789C>T synonymous_variant 0.9 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.91 isoniazid
kasA 2518910 c.796C>T synonymous_variant 0.91 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.9 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.89 isoniazid
kasA 2518951 c.837G>A synonymous_variant 0.87 isoniazid
kasA 2518960 c.846C>G synonymous_variant 0.85 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.86 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.87 isoniazid
kasA 2518978 c.864T>C synonymous_variant 0.82 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.82 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.78 isoniazid
kasA 2518993 c.879C>G synonymous_variant 0.74 isoniazid
kasA 2519008 c.894C>G synonymous_variant 0.61 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.8 isoniazid
kasA 2519251 c.1137G>A synonymous_variant 0.83 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 0.91 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 0.91 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 0.83 isoniazid
kasA 2519347 c.1233T>C synonymous_variant 0.61 isoniazid
kasA 2519359 c.1245T>C synonymous_variant 0.72 isoniazid
kasA 2519364 c.1250G>A splice_region_variant&stop_retained_variant 0.72 isoniazid
ahpC 2726255 c.63T>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
ahpC 2726258 c.66C>T synonymous_variant 0.65 isoniazid Not assoc w R - Interim
ahpC 2726264 c.72C>G synonymous_variant 0.71 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 0.92 isoniazid
ahpC 2726304 p.Ile38Val missense_variant 0.92 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.92 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.92 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.97 isoniazid
ahpC 2726324 c.132A>G synonymous_variant 0.98 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 1.0 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 1.0 isoniazid
ahpC 2726354 c.162G>C synonymous_variant 1.0 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 1.0 isoniazid
ahpC 2726378 c.186T>G synonymous_variant 1.0 isoniazid
ahpC 2726393 c.201G>C synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 0.96 isoniazid
ahpC 2726430 c.238_240delGCCinsAG frameshift_variant&missense_variant 0.93 isoniazid Uncertain significance
ahpC 2726441 c.249G>C synonymous_variant 0.92 isoniazid
ahpC 2726444 c.252G>A synonymous_variant 0.89 isoniazid Not assoc w R - Interim
ahpC 2726447 c.255T>C synonymous_variant 0.89 isoniazid
ahpC 2726450 c.258G>C synonymous_variant 0.89 isoniazid
ahpC 2726453 c.261T>C synonymous_variant 0.89 isoniazid
ahpC 2726467 p.Ala92Val missense_variant 0.85 isoniazid
ahpC 2726471 c.279T>C synonymous_variant 0.85 isoniazid
ahpC 2726483 c.291T>C synonymous_variant 0.75 isoniazid Not assoc w R - Interim
ahpC 2726486 c.294A>C synonymous_variant 0.75 isoniazid
ahpC 2726493 c.301_303delAACinsGG frameshift_variant&missense_variant 0.67 isoniazid Uncertain significance
folC 2746648 c.951G>C synonymous_variant 0.9 para-aminosalicylic_acid
folC 2746654 c.945C>G synonymous_variant 0.91 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.91 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746677 p.Ser308Ala missense_variant 0.92 para-aminosalicylic_acid
folC 2746678 c.921T>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746681 c.918C>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746684 c.915C>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746687 c.910_912delCTCinsGG frameshift_variant&missense_variant 0.92 para-aminosalicylic_acid
folC 2746728 c.871T>C synonymous_variant 0.85 para-aminosalicylic_acid
folC 2746744 c.855T>G synonymous_variant 0.5 para-aminosalicylic_acid
folC 2746747 c.852G>C synonymous_variant 0.5 para-aminosalicylic_acid
folC 2746753 c.846C>G synonymous_variant 0.5 para-aminosalicylic_acid
folC 2747041 c.558G>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747059 c.540T>A synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747071 c.528C>T synonymous_variant 0.95 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.9 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.9 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747221 c.378G>A synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747230 c.369C>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747239 c.360T>C synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747263 c.336C>A synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747278 c.321C>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747288 p.Pro104Val missense_variant 0.88 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.86 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747323 c.276C>G synonymous_variant 0.6 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747386 c.213C>G synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 0.76 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747398 c.201C>T synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747404 c.195G>C synonymous_variant 0.86 para-aminosalicylic_acid
folC 2747414 p.Arg62Leu missense_variant 0.86 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.86 para-aminosalicylic_acid
folC 2747422 c.177G>A synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747425 c.174C>T synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747439 p.Met54Leu missense_variant 0.9 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747454 c.145C>A synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 0.93 para-aminosalicylic_acid
folC 2747491 c.108A>G synonymous_variant 0.9 para-aminosalicylic_acid
folC 2747497 c.102C>G synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747500 c.99A>G synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747503 c.96T>C synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747509 c.90T>C synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747520 c.79C>T synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747521 c.78C>G synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747524 c.75G>T synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747539 c.60T>A synonymous_variant 0.75 para-aminosalicylic_acid
Rv2477c 2782419 p.Val542Ile missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782441 c.1602G>A synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782459 c.1584C>T synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782462 c.1581C>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782496 p.Asp516Ala missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782498 c.1545C>T synonymous_variant 0.99 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R
kanamycin Not assoc w R
rifampicin Not assoc w R
amikacin Not assoc w R
Rv2477c 2782504 c.1539G>A synonymous_variant 0.99 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>T synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782570 c.1473C>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782576 c.1467C>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782587 p.Leu486Val missense_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782602 c.1441C>T synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782603 c.1440G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782606 c.1435_1437delGGTinsAC frameshift_variant&missense_variant 0.86 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782612 c.1431T>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 0.87 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782864 c.1179T>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782876 c.1167G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782897 c.1146G>A synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782905 p.Val380Ile missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782918 c.1125C>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782928 p.Thr372Glu missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782930 c.1113G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782999 c.1044C>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783014 p.Ser343Thr missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783023 c.1020G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783122 c.921G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783131 c.912C>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783143 c.900G>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783188 c.855G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783238 c.804_805insAC frameshift_variant 0.71 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783241 p.Glu268Lys missense_variant 0.59 ethambutol Uncertain significance
moxifloxacin
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783243 c.798_799delGA frameshift_variant 0.67 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783247 c.796T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783248 c.795G>T synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783308 c.735G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>T synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783356 c.687C>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783373 p.Glu224Gln missense_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>A synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783476 c.567C>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>T synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783515 c.528C>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783587 c.456G>A synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783601 c.442C>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783602 c.441G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783632 c.411C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783644 p.Asp133Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783658 c.385C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783668 c.375G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.99 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.99 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 0.99 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783749 c.292_294delATCinsGA frameshift_variant&missense_variant 0.96 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783761 c.282G>A synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783785 c.258C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783791 c.252C>A synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783800 p.Glu81Asp missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783803 c.240C>T synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783837 p.Thr69Ser missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783842 c.201C>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783848 c.195C>T synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>T synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783866 c.177C>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783926 c.117C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783950 c.93C>T synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 c.87T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784016 c.27G>A synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784051 c.-9C>T upstream_gene_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784321 c.-279A>C upstream_gene_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784348 c.-306G>C upstream_gene_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784351 c.-309C>G upstream_gene_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784354 c.-312T>C upstream_gene_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784358 c.-316T>A upstream_gene_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784366 c.-324G>C upstream_gene_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784414 c.-372A>G upstream_gene_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784465 c.-423T>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784489 c.-447C>A upstream_gene_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784492 c.-450C>G upstream_gene_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784519 c.-477G>A upstream_gene_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784525 c.-483G>A upstream_gene_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784561 c.-519T>C upstream_gene_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784564 c.-522T>A upstream_gene_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784570 c.-528A>G upstream_gene_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784573 c.-531C>G upstream_gene_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784582 c.-542_-540delTTGinsCC upstream_gene_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784585 c.-543T>C upstream_gene_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784588 c.-546C>T upstream_gene_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784597 c.-555C>T upstream_gene_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859305 c.1114C>T synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859318 c.1101A>G synonymous_variant 0.88 clofazimine
bedaquiline
pepQ 2859351 c.1068G>A synonymous_variant 0.83 clofazimine
bedaquiline
pepQ 2859390 c.1029A>G synonymous_variant 0.73 clofazimine
bedaquiline
pepQ 2859431 c.988T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859438 c.981T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859468 c.951G>T synonymous_variant 0.95 clofazimine
bedaquiline
pepQ 2859489 p.Val310Ala missense_variant 0.95 clofazimine
bedaquiline
pepQ 2859510 c.909T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859528 c.891T>C synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859540 c.879A>T synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859546 c.873T>C synonymous_variant 0.89 clofazimine
bedaquiline
pepQ 2859555 p.Glu288Asp missense_variant 0.89 clofazimine
bedaquiline
pepQ 2859567 c.852C>G synonymous_variant 0.89 clofazimine
bedaquiline
pepQ 2859575 p.Ala282Thr missense_variant 0.87 clofazimine
bedaquiline
pepQ 2859581 c.838C>T synonymous_variant 0.8 clofazimine
bedaquiline
pepQ 2860236 c.183C>T synonymous_variant 0.9 clofazimine Not assoc w R - Interim
bedaquiline
pepQ 2860259 c.160T>C synonymous_variant 0.96 clofazimine
bedaquiline
pepQ 2860263 c.156C>G synonymous_variant 0.96 clofazimine
bedaquiline
pepQ 2860266 p.Asp51Glu missense_variant 0.96 clofazimine
bedaquiline
pepQ 2860272 c.147G>A synonymous_variant 0.96 clofazimine
bedaquiline
pepQ 2860275 c.144T>C synonymous_variant 0.96 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2860293 c.126A>G synonymous_variant 0.96 clofazimine
bedaquiline
pepQ 2860314 c.105C>T synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2860317 c.102A>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2860329 c.90G>C synonymous_variant 0.96 clofazimine
bedaquiline
pepQ 2860332 c.87C>T synonymous_variant 0.96 clofazimine
bedaquiline
pepQ 2860345 p.Ser25Thr missense_variant 0.95 clofazimine
bedaquiline
pepQ 2860349 p.Ile24Val missense_variant 0.95 clofazimine
bedaquiline
pepQ 2860364 c.55T>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2860365 c.54G>A synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2860370 p.Ser17Ala missense_variant 0.93 clofazimine
bedaquiline
pepQ 2860375 p.Ala15Gly missense_variant 0.93 clofazimine
bedaquiline
pepQ 2860377 c.42C>T synonymous_variant 0.89 clofazimine
bedaquiline
pepQ 2860382 p.Gln13Lys missense_variant 0.93 clofazimine
bedaquiline
pepQ 2860383 c.36A>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2860389 c.30G>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2860392 p.Lys9Asn missense_variant 0.94 clofazimine
bedaquiline
pepQ 2860397 p.Asp8His missense_variant 0.95 clofazimine
bedaquiline
pepQ 2860423 c.-5G>C upstream_gene_variant 0.98 clofazimine
bedaquiline
pepQ 2860434 c.-17_-16delGAinsT upstream_gene_variant 0.97 clofazimine
bedaquiline
pepQ 2860447 c.-29A>G upstream_gene_variant 0.98 clofazimine
bedaquiline
pepQ 2860448 c.-30C>A upstream_gene_variant 0.98 clofazimine
bedaquiline
pepQ 2860475 c.-57C>T upstream_gene_variant 0.98 clofazimine
bedaquiline
pepQ 2860476 c.-58A>G upstream_gene_variant 0.98 clofazimine
bedaquiline
pepQ 2860480 c.-62G>A upstream_gene_variant 0.98 clofazimine
bedaquiline
pepQ 2860499 c.-81C>G upstream_gene_variant 0.94 clofazimine
bedaquiline
pepQ 2860503 c.-87_-85delGAGinsCC upstream_gene_variant 0.93 clofazimine
bedaquiline
pepQ 2860511 c.-93C>T upstream_gene_variant 0.91 clofazimine
bedaquiline
pepQ 2860514 c.-96G>A upstream_gene_variant 0.91 clofazimine
bedaquiline
pepQ 2860523 c.-105T>C upstream_gene_variant 0.84 clofazimine
bedaquiline
pepQ 2860524 c.-106A>G upstream_gene_variant 0.84 clofazimine
bedaquiline
pepQ 2860535 c.-117C>G upstream_gene_variant 0.8 clofazimine
bedaquiline
Rv2681 2996200 c.-539G>C upstream_gene_variant 0.84 capreomycin
Rv2681 2996221 c.-518G>C upstream_gene_variant 0.89 capreomycin
Rv2681 2996227 c.-512A>G upstream_gene_variant 0.84 capreomycin
Rv2681 2996239 c.-500C>T upstream_gene_variant 0.8 capreomycin
Rv2681 2996248 c.-491A>T upstream_gene_variant 0.8 capreomycin
Rv2681 2996263 c.-476A>G upstream_gene_variant 0.67 capreomycin
Rv2681 2996344 c.-395C>G upstream_gene_variant 0.75 capreomycin
Rv2681 2996356 c.-383G>C upstream_gene_variant 0.81 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.85 capreomycin
Rv2681 2996365 c.-374G>C upstream_gene_variant 0.89 capreomycin
Rv2681 2996368 c.-371T>C upstream_gene_variant 0.89 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 0.9 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 0.9 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>C upstream_gene_variant 0.9 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.93 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.93 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.93 capreomycin
Rv2681 2996476 c.-263A>G upstream_gene_variant 0.94 capreomycin
Rv2681 2996482 c.-257T>C upstream_gene_variant 0.94 capreomycin
Rv2680 2996494 p.Asp130Glu missense_variant 0.93 capreomycin
Rv2681 2996539 c.-200T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996563 c.-176A>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996575 c.-164C>T upstream_gene_variant 1.0 capreomycin
Rv2681 2996581 c.-158G>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996593 c.-146T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996596 c.-143C>T upstream_gene_variant 1.0 capreomycin
Rv2681 2996602 c.-137G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996608 c.-131A>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996617 c.-122A>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996668 c.-71C>T upstream_gene_variant 0.95 capreomycin
Rv2681 2996671 c.-68C>T upstream_gene_variant 0.95 capreomycin
Rv2681 2996674 c.-65G>C upstream_gene_variant 0.95 capreomycin
Rv2681 2996680 c.-59C>T upstream_gene_variant 0.95 capreomycin
Rv2681 2996683 c.-56G>C upstream_gene_variant 0.86 capreomycin
Rv2681 2996686 c.-53C>G upstream_gene_variant 0.87 capreomycin
Rv2681 2996692 c.-47G>A upstream_gene_variant 0.87 capreomycin
Rv2681 2996695 c.-44G>C upstream_gene_variant 0.87 capreomycin
Rv2680 2996708 p.Thr202Val missense_variant 0.87 capreomycin
Rv2680 2996717 p.Gly205Ser missense_variant 0.87 capreomycin
Rv2681 2996750 p.Glu4Asp missense_variant 0.72 capreomycin
Rv2681 2996906 c.168A>G synonymous_variant 0.7 capreomycin
Rv2681 2996930 c.192C>T synonymous_variant 0.79 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 0.79 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 0.79 capreomycin
Rv2681 2996951 c.213C>T synonymous_variant 0.79 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 0.8 capreomycin
Rv2681 2996966 c.228G>T synonymous_variant 0.81 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 0.77 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 0.85 capreomycin
Rv2681 2996996 c.258C>T synonymous_variant 0.81 capreomycin
Rv2681 2997071 c.333C>T synonymous_variant 0.88 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 0.93 capreomycin
Rv2681 2997098 c.360C>G synonymous_variant 0.92 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 0.92 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 0.93 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 0.93 capreomycin Not assoc w R - Interim
Rv2681 2997126 c.388_390delCCAinsTG frameshift_variant&stop_gained 0.92 capreomycin Uncertain significance
Rv2681 2997134 c.396A>C synonymous_variant 0.92 capreomycin
Rv2681 2997149 c.411T>C synonymous_variant 0.91 capreomycin
Rv2681 2997155 c.417G>A synonymous_variant 0.93 capreomycin
Rv2681 2997176 c.438A>G synonymous_variant 0.94 capreomycin
Rv2681 2997183 c.445C>T synonymous_variant 0.94 capreomycin
Rv2681 2997189 p.Ala151Thr missense_variant 0.93 capreomycin
Rv2681 2997203 c.465G>A synonymous_variant 0.93 capreomycin
Rv2681 2997206 c.468A>G synonymous_variant 0.89 capreomycin
Rv2681 2997209 c.471T>G synonymous_variant 0.89 capreomycin Not assoc w R - Interim
Rv2681 2997212 c.474A>T synonymous_variant 0.89 capreomycin
Rv2681 2997218 c.480A>G synonymous_variant 0.89 capreomycin
Rv2681 2997219 c.481T>C synonymous_variant 0.89 capreomycin
Rv2681 2997222 p.Thr162Ala missense_variant 0.89 capreomycin
Rv2681 2997257 c.519C>T synonymous_variant 0.74 capreomycin
Rv2681 2997260 c.522G>A synonymous_variant 0.71 capreomycin
Rv2681 2997263 c.525A>G synonymous_variant 0.69 capreomycin
Rv2681 2997266 c.528C>A synonymous_variant 0.64 capreomycin
Rv2681 2997267 p.Ser177Pro missense_variant 0.64 capreomycin
Rv2681 2997299 c.561G>C synonymous_variant 0.71 capreomycin
Rv2681 2997308 c.570C>G synonymous_variant 0.71 capreomycin
Rv2681 2997314 c.576A>G synonymous_variant 0.77 capreomycin
Rv2681 2997317 c.579A>G synonymous_variant 0.77 capreomycin
Rv2681 2997323 c.585G>A synonymous_variant 0.77 capreomycin
Rv2681 2997575 c.837T>C synonymous_variant 0.63 capreomycin Not assoc w R - Interim
Rv2681 2997581 c.843T>C synonymous_variant 0.63 capreomycin
Rv2681 2997584 c.846C>A synonymous_variant 0.6 capreomycin
Rv2681 2997599 c.861A>G synonymous_variant 0.6 capreomycin
Rv2681 2997601 p.Lys288Arg missense_variant 0.6 capreomycin
Rv2681 2997605 c.867A>G synonymous_variant 0.6 capreomycin
Rv2681 2997611 p.Asp291Glu missense_variant 0.6 capreomycin
Rv2681 2997617 c.879T>C synonymous_variant 0.63 capreomycin
Rv2681 2997618 p.Val294Ile missense_variant 0.63 capreomycin
Rv2681 2997623 c.885G>T synonymous_variant 0.67 capreomycin
Rv2681 2997626 c.888A>G synonymous_variant 0.63 capreomycin
Rv2752c 3064533 c.1659G>C synonymous_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064539 c.1653T>C synonymous_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064557 c.1635T>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064566 c.1626G>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064590 c.1602C>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064596 c.1596G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064599 c.1593A>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064602 c.1590T>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064612 p.Ile527Thr missense_variant 0.95 ethambutol Uncertain significance
moxifloxacin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064614 c.1578G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064635 c.1557G>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064640 c.1552T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064653 c.1539A>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064656 c.1536G>A synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064659 c.1533G>C synonymous_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064680 c.1512C>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065163 c.1029C>A synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.988_990delGCTinsTG frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065210 c.982T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065211 c.981G>T synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065217 c.975C>T synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065226 c.966G>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065229 c.963G>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065244 c.948G>T synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065262 c.930G>A synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065271 c.921C>G synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065378 p.Val272Ile missense_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065381 p.Arg271Gly missense_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065400 c.792A>G synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065406 c.786C>G synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065517 c.673_675delCTCinsTG frameshift_variant&synonymous_variant 0.87 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065532 c.660A>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065556 c.636G>A synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065583 c.609G>C synonymous_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065594 c.598C>T synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065612 p.Thr194Ala missense_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065625 c.567G>C synonymous_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 0.98 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065652 c.540C>A synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065658 p.Pro178Leu missense_variant 0.95 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065666 c.526T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065699 p.Ile165Val missense_variant 0.93 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065703 c.489A>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065709 c.483C>T synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065712 c.480C>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065718 c.474G>C synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065875 p.Lys106Arg missense_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065877 c.315G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065889 c.303G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065892 c.300C>T synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>T synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065916 c.276T>C synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065919 c.273G>C synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065925 c.267G>C synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065947 p.Gly82Ala missense_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065952 c.240C>G synonymous_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 0.74 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065982 c.210G>C synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065993 p.Val67Ile missense_variant 0.44 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065997 c.195C>T synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066456 c.-265A>C upstream_gene_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066468 c.-277C>A upstream_gene_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>G upstream_gene_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066477 c.-286C>T upstream_gene_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066480 c.-290_-289delCCinsGT upstream_gene_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066483 c.-292T>C upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066498 c.-307C>G upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-311_-310delCGinsTC upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066513 c.-322C>A upstream_gene_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>T upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066552 c.-361C>T upstream_gene_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066592 c.-401A>C upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066630 c.-439G>C upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066648 c.-457C>T upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066657 c.-466C>A upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066714 c.-523G>T upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066729 c.-538C>T upstream_gene_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066741 c.-550T>C upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066744 c.-553C>A upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066747 c.-557_-556delAAinsTG upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066752 c.-561C>T upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066753 c.-562G>A upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066756 c.-567_-565delCGGinsAC upstream_gene_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.68 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066783 c.-592G>C upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.68 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066816 c.-625G>T upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.59 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-633_-631delGCTinsTC upstream_gene_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.59 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066855 c.-664T>C upstream_gene_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067017 c.-826G>T upstream_gene_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067028 c.-837A>G upstream_gene_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067044 c.-853C>G upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067051 c.-860G>C upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067055 c.-864A>G upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067056 c.-865T>C upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067059 c.-868G>A upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067083 c.-892C>A upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067086 c.-895A>G upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067089 c.-900_-898delCTAinsTG upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067100 c.-909G>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067230 p.Thr239Ser missense_variant 0.83 para-aminosalicylic_acid
thyX 3067247 c.699C>A synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067250 c.696G>C synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067277 c.669C>A synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067280 p.Val222Ser missense_variant 0.9 para-aminosalicylic_acid
thyX 3067284 p.Ala221Asp missense_variant 0.9 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067331 c.615C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.99 para-aminosalicylic_acid
thyX 3067394 c.552G>T synonymous_variant 0.99 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067430 c.516C>T synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067445 c.501C>A synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067463 c.481_483delATCinsGG frameshift_variant&missense_variant 0.83 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067530 p.Ala139Gly missense_variant 0.67 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.8 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067742 c.204A>T synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.94 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067784 c.162C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 0.93 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067832 c.114C>T synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067847 c.97_99delCCCinsTG frameshift_variant&missense_variant 0.95 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067889 c.55_57delGCCinsAG frameshift_variant&missense_variant 0.92 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.91 para-aminosalicylic_acid
thyX 3067916 p.Gln10His missense_variant 0.88 para-aminosalicylic_acid
thyX 3067925 c.21G>A synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067931 c.15G>C synonymous_variant 0.75 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073848 c.624C>T synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3073857 c.615C>T synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3073860 c.612C>T synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.75 para-aminosalicylic_acid
thyA 3073878 c.594G>A synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3073887 p.Ser195Asp missense_variant 0.71 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3073894 p.Gly193Asp missense_variant 0.71 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.74 para-aminosalicylic_acid
thyA 3073902 c.570C>A synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073932 c.540C>T synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3073947 c.525G>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.93 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.94 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 0.94 para-aminosalicylic_acid
thyA 3074091 c.381C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074123 p.Asp117Asn missense_variant 0.91 para-aminosalicylic_acid
thyA 3074127 c.345G>T synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074133 c.339C>T synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074151 c.321G>A synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074160 c.312A>T synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074163 c.309T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074190 c.282C>T synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074196 c.276G>T synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3074199 c.273G>A synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.85 para-aminosalicylic_acid
thyA 3074208 c.264C>T synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3074214 p.Asp86Glu missense_variant 0.87 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074247 c.225C>T synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3074252 p.Glu74Gln missense_variant 0.87 para-aminosalicylic_acid
thyA 3074256 c.216G>A synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074262 c.210T>C synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074283 c.189G>A synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074355 c.117G>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074367 c.103_105delCGCinsAG frameshift_variant&missense_variant 0.94 para-aminosalicylic_acid
thyA 3074370 p.Met34Ile missense_variant 0.94 para-aminosalicylic_acid
thyA 3074391 c.81C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074397 c.75A>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074409 c.63C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074423 p.Pro17Ala missense_variant 0.83 para-aminosalicylic_acid
thyA 3074426 p.Thr16Ser missense_variant 0.8 para-aminosalicylic_acid
ald 3087699 p.Leu294Val missense_variant 0.67 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.71 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.76 cycloserine
ald 3087727 p.Ala303Gly missense_variant 0.76 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.76 cycloserine
ald 3087738 p.Lys307Arg missense_variant 0.68 cycloserine
ald 3087743 c.924G>A synonymous_variant 0.72 cycloserine
ald 3087746 c.927G>C synonymous_variant 0.76 cycloserine
ald 3087749 c.930C>G synonymous_variant 0.76 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 0.75 cycloserine
ald 3087771 p.Met318Leu missense_variant 0.76 cycloserine
ald 3087776 c.957G>C synonymous_variant 0.76 cycloserine
ald 3087786 p.Glu323Lys missense_variant 0.79 cycloserine
fbiD 3339171 c.54C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiD 3339177 c.60C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiD 3339180 c.63G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiD 3339186 c.69A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339190 c.73A>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339215 p.Gln33Arg missense_variant 0.84 clofazimine
pretomanid
delamanid
fbiD 3339219 c.102T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiD 3339222 c.105C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiD 3339225 c.108G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiD 3339228 c.111C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiD 3339234 c.117G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiD 3339240 c.123C>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiD 3339246 c.129C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiD 3339462 c.345C>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiD 3339475 c.358T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiD 3339489 c.372A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiD 3339492 c.375C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiD 3339501 c.384A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiD 3339592 p.His159Asp missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiD 3339599 p.Arg161Gln missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339607 p.Pro164Ala missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiD 3339639 c.522C>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiD 3339642 c.525T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiD 3339651 c.534G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339654 c.537A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339666 c.549G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339675 c.558C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiD 3339690 c.573C>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiD 3339696 c.579C>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiD 3339700 c.583C>T synonymous_variant 0.58 clofazimine
pretomanid
delamanid
Rv3236c 3612621 c.496T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
Rv3236c 3612628 c.489G>C synonymous_variant 0.72 pyrazinamide
Rv3236c 3612667 c.450T>G synonymous_variant 0.91 pyrazinamide
Rv3236c 3612673 c.444G>C synonymous_variant 0.91 pyrazinamide
Rv3236c 3612679 c.438G>C synonymous_variant 0.9 pyrazinamide
Rv3236c 3612688 c.429C>G synonymous_variant 0.97 pyrazinamide
Rv3236c 3612691 c.426G>C synonymous_variant 0.97 pyrazinamide
Rv3236c 3612694 c.423T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
Rv3236c 3612706 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
Rv3236c 3612712 c.405G>A synonymous_variant 0.96 pyrazinamide
Rv3236c 3612721 c.396G>C synonymous_variant 0.88 pyrazinamide
Rv3236c 3612730 c.387C>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
Rv3236c 3612733 c.384C>G synonymous_variant 0.73 pyrazinamide
Rv3236c 3612742 c.375C>A synonymous_variant 0.75 pyrazinamide
Rv3236c 3612796 c.319_321delGCGinsAC frameshift_variant&missense_variant 0.77 pyrazinamide Uncertain significance
Rv3236c 3612805 c.312T>C synonymous_variant 0.87 pyrazinamide
Rv3236c 3612829 c.288T>C synonymous_variant 0.87 pyrazinamide
Rv3236c 3612835 c.282T>C synonymous_variant 0.91 pyrazinamide
Rv3236c 3612838 c.279G>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
Rv3236c 3612850 c.267C>T synonymous_variant 0.81 pyrazinamide
Rv3236c 3612853 c.264C>T synonymous_variant 0.81 pyrazinamide
Rv3236c 3612856 c.261C>T synonymous_variant 0.77 pyrazinamide
Rv3236c 3612862 c.255T>C synonymous_variant 0.77 pyrazinamide
Rv3236c 3612874 c.243G>A synonymous_variant 0.8 pyrazinamide
Rv3236c 3612883 c.234T>C synonymous_variant 0.78 pyrazinamide
Rv3236c 3612886 c.231T>C synonymous_variant 0.76 pyrazinamide
Rv3236c 3612895 c.222T>C synonymous_variant 0.69 pyrazinamide
lpqB 3623384 c.1527C>T synonymous_variant 0.92 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623388 p.Thr508Asn missense_variant 0.94 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623428 c.1483T>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3623443 p.Ser490Thr missense_variant 0.98 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623471 c.1440C>T synonymous_variant 0.99 bedaquiline
rifampicin
lpqB 3623489 c.1422C>T synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623492 c.1419T>C synonymous_variant 0.99 bedaquiline
rifampicin
lpqB 3623510 c.1401C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623531 p.Gly460Asp missense_variant 0.96 bedaquiline
rifampicin
lpqB 3623549 c.1362C>G synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3623561 c.1350T>C synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3623564 c.1347C>T synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3623576 c.1335T>C synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 0.89 bedaquiline
rifampicin
lpqB 3623588 c.1323G>C synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3623594 c.1317C>T synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3623600 c.1311C>T synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3623605 p.Ala436Ser missense_variant 0.95 bedaquiline
rifampicin
lpqB 3623614 p.Thr433Ala missense_variant 0.9 bedaquiline
rifampicin
lpqB 3623615 c.1296G>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623624 c.1287G>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623627 c.1284T>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623677 p.Val412Ile missense_variant 0.77 bedaquiline
rifampicin
lpqB 3623684 c.1227T>C synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3623690 c.1221G>C synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3623699 c.1212C>G synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3623714 c.1197G>A synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623732 c.1179G>T synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623736 p.Ser392Asn missense_variant 0.93 bedaquiline
rifampicin
lpqB 3623738 c.1173C>T synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623741 c.1170G>C synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3623750 c.1161C>G synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3623756 c.1155G>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3623782 p.Val377Ile missense_variant 0.95 bedaquiline
rifampicin
lpqB 3623789 c.1122T>C synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3623792 c.1119G>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623799 p.Glu371Val missense_variant 0.88 bedaquiline
rifampicin
lpqB 3623804 c.1107G>C synonymous_variant 0.87 bedaquiline
rifampicin
lpqB 3623807 c.1104T>C synonymous_variant 0.86 bedaquiline
rifampicin
lpqB 3623810 c.1101G>T synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623813 c.1098C>T synonymous_variant 0.8 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623818 p.Gly365Arg missense_variant 0.8 bedaquiline
rifampicin
lpqB 3623987 c.924G>C synonymous_variant 0.86 bedaquiline
rifampicin
lpqB 3624002 c.909G>C synonymous_variant 0.88 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624008 c.903T>C synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624014 c.897T>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624017 p.Thr298Asn missense_variant 0.92 bedaquiline
rifampicin
lpqB 3624023 c.888G>A synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3624026 c.885G>A synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624041 p.Glu290Asp missense_variant 0.93 bedaquiline
rifampicin
lpqB 3624071 c.840C>T synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3624080 c.831G>A synonymous_variant 0.95 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624094 c.817A>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624098 c.813G>A synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624101 c.810C>A synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>C synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624152 c.759C>G synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.8 bedaquiline
rifampicin
lpqB 3624172 p.Val247Ile missense_variant 0.67 bedaquiline
rifampicin
lpqB 3624173 c.738A>C synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624176 c.735G>A synonymous_variant 0.62 bedaquiline
rifampicin
lpqB 3624179 c.732C>G synonymous_variant 0.62 bedaquiline
rifampicin
lpqB 3624188 c.723G>C synonymous_variant 0.73 bedaquiline
rifampicin
lpqB 3624191 p.Arg240Lys missense_variant 0.67 bedaquiline
rifampicin
lpqB 3624200 c.711A>C synonymous_variant 0.84 bedaquiline
rifampicin
lpqB 3624209 c.702A>C synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624221 c.690G>T synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624224 c.687T>C synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624227 c.684G>A synonymous_variant 0.8 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624233 c.678G>C synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624236 c.675C>T synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624239 c.672G>A synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624242 c.669A>G synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624245 c.666A>G synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624257 c.654C>G synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3624263 c.648T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624276 p.Arg212His missense_variant 0.96 bedaquiline
rifampicin
lpqB 3624280 p.Ala211Thr missense_variant 0.96 bedaquiline
rifampicin
lpqB 3624290 c.621C>T synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624301 p.Ala204Ser missense_variant 0.96 bedaquiline
rifampicin
lpqB 3624302 c.609G>A synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624308 c.603A>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624314 c.597C>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624317 c.594C>G synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 0.97 bedaquiline
rifampicin
lpqB 3624341 c.570C>T synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624356 c.555C>T synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624368 c.543C>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3624406 c.505C>T synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 0.94 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624467 c.444C>G synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3624482 c.429T>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624486 p.Asp142Gly missense_variant 0.91 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624490 p.Ser141Pro missense_variant 0.93 bedaquiline
rifampicin
lpqB 3624491 c.420G>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624503 c.408G>A synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624521 c.390G>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3624527 c.384A>G synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3624530 c.381T>C synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624629 c.282G>T synonymous_variant 0.87 bedaquiline
rifampicin
lpqB 3624635 c.276C>T synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3624650 c.261G>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3624671 c.240C>A synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624680 c.231T>A synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 0.92 bedaquiline
rifampicin Uncertain significance
lpqB 3624704 c.207G>A synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624707 c.204G>A synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624713 c.198C>T synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 0.93 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624725 c.186G>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624734 c.177A>C synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624752 c.159C>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 0.93 bedaquiline
rifampicin Uncertain significance
lpqB 3624776 c.135T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625009 c.-99G>A upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3625032 c.1582C>T synonymous_variant 0.88 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625045 c.-135C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3625089 p.Ala509Ser missense_variant 0.93 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Gln missense_variant 0.95 bedaquiline
rifampicin
lpqB 3625099 c.-189C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625105 c.-195C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625111 c.-201G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625114 c.-204G>A upstream_gene_variant 0.86 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 0.84 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625132 c.1480_1482delTTGinsCA frameshift_variant&missense_variant 0.83 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625135 c.1479A>G synonymous_variant 0.8 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.82 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625177 c.-267C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3625204 c.1408_1410delTCGinsGC frameshift_variant&missense_variant 0.83 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625216 c.-306G>A upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625231 c.-321G>A upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625273 c.-363C>G upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625282 c.-372C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.99 bedaquiline
rifampicin
lpqB 3625309 c.-399C>T upstream_gene_variant 0.99 bedaquiline
rifampicin
lpqB 3625327 c.-417A>G upstream_gene_variant 0.99 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625366 c.-456C>A upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625384 c.-474G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625387 c.-477T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625396 c.-486G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625405 c.1207_1209delCAGinsGA frameshift_variant&missense_variant 0.8 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625408 c.1204_1206delGAGinsCC frameshift_variant&missense_variant 0.75 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625414 c.-504C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625419 c.1195C>T synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625420 p.Asp398Glu missense_variant 0.79 bedaquiline
rifampicin
lpqB 3625426 c.-516G>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625432 c.-522G>A upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625459 c.-549C>G upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625465 c.-555T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625471 c.-561C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625474 c.-564G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625480 p.Asn378Lys missense_variant 0.94 bedaquiline
rifampicin
lpqB 3625486 c.-576G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625489 c.-579A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3625497 c.1117T>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625510 c.-600T>G upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625518 c.-608T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625522 c.-612C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.96 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625588 c.-678G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625612 c.-702G>T upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625615 c.-705G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625648 c.-738T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625663 c.-753G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625684 c.-774G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625747 c.-837G>T upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625750 c.864G>A synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.96 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625798 c.-888G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625803 c.-893C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625804 c.808_810delAGGinsCA frameshift_variant&missense_variant 0.97 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625819 c.795G>A synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625837 c.-927C>A upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625840 c.-930A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625873 c.741C>T synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625876 c.-966G>A upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625903 c.-993G>C upstream_gene_variant 0.84 bedaquiline
rifampicin
lpqB 3625906 c.-996G>A upstream_gene_variant 0.84 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3625915 c.699G>A synonymous_variant 0.86 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.75 bedaquiline
rifampicin
mtrB 3625935 p.Ala227Ser missense_variant 0.6 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625936 c.678C>G synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625939 c.675G>A synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3625945 c.669A>G synonymous_variant 0.82 bedaquiline
rifampicin
mtrB 3625951 c.663A>G synonymous_variant 0.85 bedaquiline
rifampicin
mtrB 3625959 p.Gly219Ser missense_variant 0.84 bedaquiline
rifampicin
mtrB 3625963 c.651C>G synonymous_variant 0.85 bedaquiline
rifampicin
mtrB 3625966 c.648C>A synonymous_variant 0.86 bedaquiline
rifampicin
mtrB 3625972 c.642G>C synonymous_variant 0.88 bedaquiline
rifampicin
mtrB 3625978 c.636T>C synonymous_variant 0.88 bedaquiline
rifampicin
mtrB 3625989 p.Thr209Ala missense_variant 0.86 bedaquiline
rifampicin
mtrB 3625993 c.621G>C synonymous_variant 0.89 bedaquiline
rifampicin
mtrB 3625999 c.615A>G synonymous_variant 0.86 bedaquiline
rifampicin
mtrB 3626006 p.Ser203Asn missense_variant 0.88 bedaquiline
rifampicin
mtrB 3626008 c.606G>T synonymous_variant 0.88 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626029 c.585A>G synonymous_variant 0.91 bedaquiline
rifampicin
mtrB 3626043 p.Ala191Thr missense_variant 0.93 bedaquiline
rifampicin
mtrB 3626054 p.Leu187Ser missense_variant 0.83 bedaquiline
rifampicin
mtrB 3626062 c.552T>G synonymous_variant 0.76 bedaquiline
rifampicin
mtrB 3626065 c.549G>C synonymous_variant 0.71 bedaquiline
rifampicin
mtrB 3626070 p.Ile182Val missense_variant 0.67 bedaquiline
rifampicin
mtrB 3626071 c.543C>T synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626074 c.540G>C synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626296 c.318T>C synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626302 c.312G>C synonymous_variant 0.56 bedaquiline
rifampicin
mtrB 3626308 c.306T>C synonymous_variant 0.56 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626317 c.297A>G synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626323 c.291G>C synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626329 c.285G>A synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626332 c.282T>C synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626344 c.270G>C synonymous_variant 0.74 bedaquiline
rifampicin
mtrB 3626357 p.Thr86Asn missense_variant 0.75 bedaquiline
rifampicin
mtrB 3626359 c.255C>G synonymous_variant 0.77 bedaquiline
rifampicin
mtrB 3626362 c.252A>C synonymous_variant 0.78 bedaquiline
rifampicin
mtrB 3626372 p.Ile81Thr missense_variant 0.81 bedaquiline
rifampicin
mtrB 3626383 c.231G>C synonymous_variant 0.75 bedaquiline
rifampicin
mtrB 3626386 c.228G>C synonymous_variant 0.75 bedaquiline
rifampicin
mtrB 3626390 p.Arg75Lys missense_variant 0.75 bedaquiline
rifampicin
mtrB 3626394 p.Val74Leu missense_variant 0.77 bedaquiline
rifampicin
mtrB 3626395 c.219G>A synonymous_variant 0.77 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 0.82 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 0.83 bedaquiline
rifampicin
mtrB 3626410 c.204T>G synonymous_variant 0.84 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626437 c.177T>C synonymous_variant 0.85 bedaquiline
rifampicin
mtrB 3626440 c.174C>G synonymous_variant 0.82 bedaquiline
rifampicin
mtrB 3626443 c.171T>C synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626455 c.159C>G synonymous_variant 0.88 bedaquiline
rifampicin
mtrB 3626458 c.156C>A synonymous_variant 0.88 bedaquiline
rifampicin
mtrB 3626461 c.153A>G synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626467 c.147G>T synonymous_variant 0.88 bedaquiline
rifampicin
mtrB 3626473 c.141T>G synonymous_variant 0.83 bedaquiline
rifampicin
mtrB 3626476 c.138C>G synonymous_variant 0.8 bedaquiline
rifampicin
mtrB 3626497 c.117G>A synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626502 c.112C>T synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626711 c.-98T>A upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626776 c.-163A>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626849 c.-236C>T upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626852 c.-239G>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626936 c.-323C>A upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 0.9 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3626963 c.387G>A synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626981 c.-368C>T upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626990 c.-377G>A upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3627002 c.-389G>A upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3627056 c.294C>T synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627140 c.-527G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627155 c.-542C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.95 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627227 c.123T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627242 c.108C>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627266 c.-653A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3627296 c.-683T>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627311 c.39C>T synonymous_variant 0.91 bedaquiline Not assoc w R - Interim
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3627323 c.25_27delTTGinsCC frameshift_variant&missense_variant 0.9 bedaquiline
rifampicin
mtrB 3627354 c.-741A>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627358 c.-9G>A upstream_gene_variant 0.7 bedaquiline
rifampicin Uncertain significance
mtrB 3627360 c.-747G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627362 c.-749A>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrA 3627875 c.-527_-526delTGinsCA upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3627884 c.-535A>G upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3627901 c.-552G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrA 3627917 c.-568G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3627920 c.-571A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
fbiA 3640225 c.-318G>T upstream_gene_variant 0.71 clofazimine
pretomanid
delamanid
fbiA 3640232 c.-311T>C upstream_gene_variant 0.87 clofazimine
pretomanid
delamanid
fbiA 3640247 c.-296T>G upstream_gene_variant 0.91 clofazimine
pretomanid
delamanid
fbiA 3640260 c.-283T>C upstream_gene_variant 0.91 clofazimine
pretomanid
delamanid
fbiA 3640261 c.-282C>T upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiA 3640269 c.-274A>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiA 3640282 c.-261C>G upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiA 3640298 c.-245A>G upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fbiA 3640318 c.-225A>T upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3640365 c.-178C>G upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fbiA 3640392 c.-151A>G upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640393 c.-150A>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640394 c.-149G>A upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640400 c.-143G>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640402 c.-141C>G upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640403 c.-140G>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640413 c.-130T>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640414 c.-129G>A upstream_gene_variant 0.86 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiA 3640416 c.-127G>T upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3640433 c.-110T>C upstream_gene_variant 0.8 clofazimine
pretomanid
delamanid
fbiA 3640442 c.-101A>G upstream_gene_variant 0.77 clofazimine
pretomanid
delamanid
fbiA 3640445 c.-98A>C upstream_gene_variant 0.75 clofazimine
pretomanid
delamanid
fbiB 3641187 c.-348T>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3641208 c.666C>T synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiB 3641217 c.-318C>G upstream_gene_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3641226 c.-309G>C upstream_gene_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3641229 c.-306T>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3641232 c.-303C>T upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3641235 c.-300G>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3641239 c.-296T>C upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3641246 p.Glu235Ala missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3641251 p.Thr237Pro missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3641256 c.-279A>G upstream_gene_variant 0.86 clofazimine
pretomanid
delamanid
fbiA 3641286 c.744C>A synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiA 3641288 p.Glu249Gly missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiB 3641292 c.-243G>A upstream_gene_variant 0.87 clofazimine
pretomanid
delamanid
fbiA 3641314 p.Thr258Ala missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiB 3641319 c.-216C>T upstream_gene_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3641322 c.-213T>C upstream_gene_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3641328 c.-207T>A upstream_gene_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3641352 c.-183C>G upstream_gene_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3641355 c.-180T>G upstream_gene_variant 0.88 clofazimine
pretomanid
delamanid
fbiA 3641374 p.Ala278Ser missense_variant 0.76 clofazimine
pretomanid
delamanid
fbiB 3641855 c.321C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3641874 p.Gly114Asn missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3641880 p.Ser116Asn missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3641885 c.351G>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiB 3641888 c.354A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3641900 c.366G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641909 c.375T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641924 c.390A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641925 p.Thr131Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641928 c.394T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641948 c.414G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641951 c.417G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641957 c.423C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641966 c.432C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641969 c.435C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641975 c.441C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641976 p.Ile148Val missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641993 c.459A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3642006 p.Asn158Cys missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642596 c.1062C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642599 p.Asp355Glu missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642609 p.Ser359Ala missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642623 c.1089C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642626 c.1092C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642630 p.Thr366Gly missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642633 p.Asp367His missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642665 c.1131C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3642671 c.1137G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3642674 c.1140C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3642692 c.1158C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3642695 c.1161G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642707 c.1173C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
alr 3840200 c.1220delA frameshift_variant 0.8 cycloserine
alr 3840213 p.Arg403Leu missense_variant 0.92 cycloserine
alr 3840225 p.Thr399Ser missense_variant 0.92 cycloserine
alr 3840230 c.1191T>G synonymous_variant 0.92 cycloserine
alr 3840236 c.1185A>G synonymous_variant 0.93 cycloserine
alr 3840242 c.1179C>T synonymous_variant 0.94 cycloserine
alr 3840248 c.1173C>A synonymous_variant 0.95 cycloserine
alr 3840272 c.1149C>G synonymous_variant 0.93 cycloserine
alr 3840275 c.1146T>G synonymous_variant 0.93 cycloserine
alr 3840293 c.1128T>G synonymous_variant 0.91 cycloserine
alr 3840296 c.1125G>C synonymous_variant 0.91 cycloserine
alr 3840305 c.1116T>C synonymous_variant 0.92 cycloserine
alr 3840312 p.Ile370Ala missense_variant 0.93 cycloserine
alr 3840317 c.1104G>C synonymous_variant 0.93 cycloserine
alr 3840328 c.1093T>C synonymous_variant 0.95 cycloserine
alr 3840332 c.1089G>C synonymous_variant 0.94 cycloserine
alr 3840341 c.1080C>T synonymous_variant 0.86 cycloserine
alr 3840353 c.1068T>C synonymous_variant 0.71 cycloserine
alr 3840356 c.1063_1065delCTTinsGC frameshift_variant&missense_variant 0.71 cycloserine
alr 3840362 c.1059G>C synonymous_variant 0.75 cycloserine
alr 3840371 c.1050G>C synonymous_variant 0.78 cycloserine
alr 3840380 c.1039_1041delATGinsGC frameshift_variant&missense_variant 0.71 cycloserine
alr 3840443 c.978G>C synonymous_variant 0.88 cycloserine
alr 3840446 c.975G>T synonymous_variant 0.89 cycloserine
alr 3840473 c.948C>T synonymous_variant 0.92 cycloserine
alr 3840476 c.945A>C synonymous_variant 0.94 cycloserine
alr 3840502 p.Leu307Val missense_variant 0.98 cycloserine
alr 3840503 p.Asn306Thr missense_variant 0.98 cycloserine
alr 3840513 p.Arg303His missense_variant 0.95 cycloserine
alr 3840515 c.906A>G synonymous_variant 0.95 cycloserine
alr 3840527 c.894A>C synonymous_variant 0.95 cycloserine
alr 3840536 c.885T>C synonymous_variant 0.89 cycloserine
alr 3841070 c.351C>T synonymous_variant 0.85 cycloserine
alr 3841082 c.339G>C synonymous_variant 0.82 cycloserine
alr 3841100 c.321A>G synonymous_variant 0.82 cycloserine
alr 3841106 c.315T>C synonymous_variant 0.88 cycloserine
alr 3841112 c.309T>C synonymous_variant 0.88 cycloserine
alr 3841115 c.306T>C synonymous_variant 0.88 cycloserine
alr 3841123 c.298C>T synonymous_variant 0.82 cycloserine
alr 3841127 c.294A>G synonymous_variant 0.82 cycloserine
rpoA 3877482 c.1026C>A synonymous_variant 0.88 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 0.91 rifampicin Uncertain significance
rpoA 3877503 c.1003_1005delGCGinsTC frameshift_variant&missense_variant 0.92 rifampicin
rpoA 3877506 c.1002C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877512 c.996C>G synonymous_variant 0.93 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.94 rifampicin
rpoA 3877533 c.975C>G synonymous_variant 0.95 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877567 p.Ser314Thr missense_variant 0.95 rifampicin
rpoA 3877569 c.939G>C synonymous_variant 0.95 rifampicin
rpoA 3877575 c.933C>T synonymous_variant 0.96 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877602 c.906C>T synonymous_variant 0.95 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.95 rifampicin
rpoA 3877620 c.888G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>A synonymous_variant 0.94 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877659 c.849G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.93 rifampicin
rpoA 3877674 c.834C>T synonymous_variant 0.91 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.9 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877685 c.823C>T synonymous_variant 0.9 rifampicin
rpoA 3877689 c.819C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.93 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.93 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.92 rifampicin
rpoA 3877737 c.771G>T synonymous_variant 0.92 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877746 c.762G>C synonymous_variant 0.93 rifampicin
rpoA 3877752 c.756C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877755 c.753C>A synonymous_variant 0.95 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 0.97 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.97 rifampicin
rpoA 3877886 c.622C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 0.95 rifampicin
rpoA 3877899 p.Ser203Thr missense_variant 0.93 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.89 rifampicin
rpoA 3877926 c.582G>C synonymous_variant 0.91 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 0.9 rifampicin
rpoA 3877950 c.558C>T synonymous_variant 0.91 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.91 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.93 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.96 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.96 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.94 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.94 rifampicin
rpoA 3878043 c.465G>T synonymous_variant 0.95 rifampicin
rpoA 3878058 c.450G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878061 c.447G>C synonymous_variant 0.96 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.97 rifampicin
rpoA 3878085 c.423G>A synonymous_variant 0.96 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 0.95 rifampicin
rpoA 3878100 c.408C>G synonymous_variant 0.95 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.96 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.97 rifampicin
rpoA 3878126 c.382C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878127 c.381G>C synonymous_variant 0.98 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.96 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.94 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 0.94 rifampicin
rpoA 3878211 c.297G>A synonymous_variant 0.94 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.92 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.95 rifampicin
rpoA 3878262 c.246C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.95 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 0.95 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878364 c.144A>T synonymous_variant 0.94 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.94 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.93 rifampicin
rpoA 3878376 c.132G>A synonymous_variant 0.94 rifampicin
rpoA 3878381 c.127C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878391 c.117T>A synonymous_variant 0.94 rifampicin
rpoA 3878403 c.105C>T synonymous_variant 0.92 rifampicin
rpoA 3878406 c.102G>T synonymous_variant 0.91 rifampicin
rpoA 3878412 c.96C>T synonymous_variant 0.91 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.92 rifampicin
rpoA 3878442 p.Val22Thr missense_variant 0.89 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.93 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.94 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.93 rifampicin
rpoA 3878483 c.25C>T synonymous_variant 0.93 rifampicin
rpoA 3878490 c.18C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878496 c.12A>T synonymous_variant 0.94 rifampicin
rpoA 3878512 c.-6_-5insGAA upstream_gene_variant 0.9 rifampicin Uncertain significance
rpoA 3878548 c.-41C>A upstream_gene_variant 0.88 rifampicin
rpoA 3878665 c.-158A>G upstream_gene_variant 0.69 rifampicin Uncertain significance
rpoA 3878672 c.-165A>T upstream_gene_variant 0.82 rifampicin
rpoA 3878680 c.-173C>T upstream_gene_variant 0.84 rifampicin Uncertain significance
rpoA 3878698 c.-191A>C upstream_gene_variant 0.91 rifampicin
rpoA 3878713 c.-206G>C upstream_gene_variant 0.91 rifampicin
rpoA 3878719 c.-212G>A upstream_gene_variant 0.91 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.91 rifampicin
rpoA 3878728 c.-221G>A upstream_gene_variant 0.91 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.93 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.96 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.92 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.91 rifampicin Uncertain significance
rpoA 3878791 c.-284C>T upstream_gene_variant 0.91 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.91 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.95 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.94 rifampicin
rpoA 3878833 c.-326C>T upstream_gene_variant 0.92 rifampicin
rpoA 3878836 c.-330_-329delAGinsCC upstream_gene_variant 0.92 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.92 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.91 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.9 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.93 rifampicin Uncertain significance
rpoA 3878920 c.-413C>T upstream_gene_variant 0.91 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.89 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 0.87 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.87 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.91 rifampicin Uncertain significance
rpoA 3878977 c.-470C>G upstream_gene_variant 0.91 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.92 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.92 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGA upstream_gene_variant 0.9 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.93 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.95 rifampicin
rpoA 3879043 c.-536C>G upstream_gene_variant 0.95 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.94 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.94 rifampicin
rpoA 3879100 c.-593G>A upstream_gene_variant 0.95 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.95 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 0.95 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.96 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.96 rifampicin
rpoA 3879172 c.-665C>T upstream_gene_variant 0.97 rifampicin
rpoA 3879184 c.-677G>A upstream_gene_variant 0.98 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.98 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.98 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.97 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.97 rifampicin
rpoA 3879235 c.-728C>T upstream_gene_variant 0.97 rifampicin
rpoA 3879238 c.-731C>T upstream_gene_variant 0.97 rifampicin
ddn 3986636 c.-208C>A upstream_gene_variant 0.98 delamanid
pretomanid
ddn 3986637 c.-207C>T upstream_gene_variant 0.98 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.97 delamanid
pretomanid
ddn 3986657 c.-187C>G upstream_gene_variant 0.98 delamanid
pretomanid
ddn 3986663 c.-181G>A upstream_gene_variant 0.98 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.98 delamanid
pretomanid
ddn 3986696 c.-148G>T upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986711 c.-133C>G upstream_gene_variant 0.88 delamanid
pretomanid
ddn 3986930 c.87C>T synonymous_variant 0.9 delamanid
pretomanid
ddn 3986933 c.90C>A synonymous_variant 0.91 delamanid
pretomanid
ddn 3986941 p.Asp33Gly missense_variant 0.86 delamanid
pretomanid
ddn 3986945 c.102G>C synonymous_variant 0.87 delamanid
pretomanid
ddn 3986951 c.108T>C synonymous_variant 0.9 delamanid
pretomanid
ddn 3986954 c.111G>C synonymous_variant 0.88 delamanid
pretomanid
ddn 3986957 c.114C>T synonymous_variant 0.88 delamanid
pretomanid
ddn 3986975 c.132T>C synonymous_variant 0.91 delamanid
pretomanid
ddn 3986984 c.141G>T synonymous_variant 0.94 delamanid
pretomanid
ddn 3987020 c.177G>A synonymous_variant 0.91 delamanid
pretomanid
ddn 3987028 p.Asn62Ser missense_variant 0.88 delamanid
pretomanid
ddn 3987035 c.192C>G synonymous_variant 0.91 delamanid
pretomanid
ddn 3987053 c.210T>C synonymous_variant 0.92 delamanid
pretomanid
ddn 3987055 p.Gly71Asp missense_variant 0.91 delamanid
pretomanid
ddn 3987062 c.219C>G synonymous_variant 0.92 delamanid
pretomanid
ddn 3987065 c.222T>C synonymous_variant 0.92 delamanid
pretomanid
ddn 3987071 c.228G>C synonymous_variant 0.92 delamanid
pretomanid
ddn 3987089 c.246G>C synonymous_variant 0.92 delamanid
pretomanid
ddn 3987092 p.Glu83Asp missense_variant 0.94 delamanid Uncertain significance
pretomanid
ddn 3987098 c.255C>T synonymous_variant 0.95 delamanid
pretomanid
ddn 3987138 p.Gln99Ser missense_variant 0.93 delamanid
pretomanid
ddn 3987143 c.300A>G synonymous_variant 0.93 delamanid Not assoc w R - Interim
pretomanid
ddn 3987164 c.321G>C synonymous_variant 0.9 delamanid
pretomanid
ddn 3987167 c.324C>T synonymous_variant 0.9 delamanid
pretomanid
ddn 3987170 c.327T>C synonymous_variant 0.9 delamanid
pretomanid
ddn 3987179 c.336G>C synonymous_variant 0.95 delamanid
pretomanid
ddn 3987185 c.342G>C synonymous_variant 0.9 delamanid
pretomanid
ddn 3987194 c.351G>A synonymous_variant 0.87 delamanid
pretomanid
clpC1 4038200 c.2505T>C synonymous_variant 0.88 pyrazinamide
clpC1 4038238 p.Thr823Ala missense_variant 0.97 pyrazinamide
clpC1 4038239 c.2466T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.97 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.98 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.98 pyrazinamide
clpC1 4038335 c.2370C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4038344 c.2361G>A synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4038350 c.2355C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038383 c.2322G>A synonymous_variant 0.94 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.94 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 0.94 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.94 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.97 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 0.97 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.96 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.96 pyrazinamide
clpC1 4038533 c.2172C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038587 c.2118C>T synonymous_variant 0.99 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.99 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.97 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038665 c.2040C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038668 c.2037G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038677 c.2028G>A synonymous_variant 0.98 pyrazinamide
clpC1 4038686 c.2019C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038695 c.2010C>A synonymous_variant 0.98 pyrazinamide
clpC1 4038698 c.2007C>G synonymous_variant 0.98 pyrazinamide
clpC1 4038703 c.2002C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.98 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.97 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4038800 c.1905C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 0.97 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 0.99 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.99 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.98 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 0.95 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038995 c.1710G>A synonymous_variant 0.94 pyrazinamide
clpC1 4039009 c.1696C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.95 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 0.92 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 0.95 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.96 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039442 c.1261_1263delCTAinsTG frameshift_variant&synonymous_variant 0.94 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039484 c.1221T>G synonymous_variant 0.94 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039514 c.1191C>T synonymous_variant 0.98 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039541 c.1164C>A synonymous_variant 0.98 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 0.97 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039693 c.1012C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.97 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039754 c.951G>T synonymous_variant 0.93 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>G synonymous_variant 0.91 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039784 c.921C>T synonymous_variant 0.82 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.77 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.96 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039942 c.763C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 0.96 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040033 c.672G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040091 c.613_614delTCinsAG synonymous_variant 0.94 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.98 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040284 c.421C>T synonymous_variant 0.83 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.83 pyrazinamide
clpC1 4040314 c.391C>T synonymous_variant 0.84 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.86 pyrazinamide
clpC1 4040336 c.369G>T synonymous_variant 0.86 pyrazinamide
clpC1 4040342 c.363C>T synonymous_variant 0.84 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.84 pyrazinamide
clpC1 4040351 c.354C>T synonymous_variant 0.84 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.89 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.87 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.8 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040531 c.174T>G synonymous_variant 0.84 pyrazinamide
clpC1 4040546 c.159G>T synonymous_variant 0.9 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.95 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040594 c.111G>T synonymous_variant 0.96 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.96 pyrazinamide
clpC1 4040636 c.69C>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040644 c.61A>C synonymous_variant 0.99 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.98 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040662 c.43C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040674 c.31A>C synonymous_variant 0.96 pyrazinamide
clpC1 4040708 c.-4A>G upstream_gene_variant 0.86 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.83 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 0.9 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.96 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.97 pyrazinamide
panD 4044210 c.72C>G synonymous_variant 0.98 pyrazinamide
panD 4044219 c.63C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
panD 4044224 c.58C>T synonymous_variant 0.92 pyrazinamide
panD 4044228 c.54C>G synonymous_variant 0.92 pyrazinamide
panD 4044243 c.39C>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
panD 4044246 c.36C>T synonymous_variant 0.92 pyrazinamide
panD 4044270 c.12G>A synonymous_variant 0.9 pyrazinamide
panD 4044284 c.-3C>T upstream_gene_variant 0.84 pyrazinamide
panD 4044287 c.-6A>G upstream_gene_variant 0.86 pyrazinamide
panD 4044294 c.-13A>C upstream_gene_variant 0.82 pyrazinamide
panD 4044644 c.-363A>G upstream_gene_variant 0.95 pyrazinamide
panD 4044647 c.-366C>T upstream_gene_variant 0.96 pyrazinamide
panD 4044662 c.-381C>G upstream_gene_variant 0.96 pyrazinamide
panD 4044672 c.-392_-391delGCinsCA upstream_gene_variant 0.94 pyrazinamide
panD 4044674 c.-393C>G upstream_gene_variant 0.92 pyrazinamide
panD 4044677 c.-396T>C upstream_gene_variant 0.92 pyrazinamide
panD 4044682 c.-401C>G upstream_gene_variant 0.94 pyrazinamide
panD 4044686 c.-407_-405delTTCinsCG upstream_gene_variant 0.94 pyrazinamide
panD 4044710 c.-429G>C upstream_gene_variant 0.93 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.86 pyrazinamide
panD 4044743 c.-463_-462delTCinsAT upstream_gene_variant 0.75 pyrazinamide
panD 4044746 c.-466_-465delTGinsCC upstream_gene_variant 0.74 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.7 pyrazinamide
panD 4044755 c.-474G>C upstream_gene_variant 0.7 pyrazinamide
panD 4044758 c.-477C>G upstream_gene_variant 0.7 pyrazinamide
panD 4044761 c.-480G>C upstream_gene_variant 0.74 pyrazinamide
panD 4044776 c.-495G>A upstream_gene_variant 0.88 pyrazinamide
panD 4044779 c.-498A>C upstream_gene_variant 0.88 pyrazinamide
panD 4044785 c.-504C>G upstream_gene_variant 0.82 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.82 pyrazinamide
panD 4044797 c.-516C>G upstream_gene_variant 0.78 pyrazinamide
panD 4044871 c.-590C>A upstream_gene_variant 0.75 pyrazinamide
panD 4044872 c.-591C>G upstream_gene_variant 0.75 pyrazinamide
panD 4044881 c.-600T>C upstream_gene_variant 0.75 pyrazinamide
panD 4044895 c.-614A>G upstream_gene_variant 0.9 pyrazinamide
panD 4044896 c.-615T>G upstream_gene_variant 0.9 pyrazinamide
panD 4044899 c.-618A>G upstream_gene_variant 0.9 pyrazinamide
panD 4044904 c.-623A>G upstream_gene_variant 0.9 pyrazinamide
panD 4044920 c.-639C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044929 c.-648G>T upstream_gene_variant 1.0 pyrazinamide
panD 4044935 c.-654A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044943 c.-662C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.92 pyrazinamide
panD 4044983 c.-702G>C upstream_gene_variant 0.92 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.92 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.94 pyrazinamide
panD 4045013 c.-732C>A upstream_gene_variant 0.85 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.85 pyrazinamide
panD 4045025 c.-744C>G upstream_gene_variant 0.86 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.88 pyrazinamide
panD 4045041 c.-761_-760delGTinsAC upstream_gene_variant 0.93 pyrazinamide
panD 4045045 c.-764C>A upstream_gene_variant 0.93 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.9 pyrazinamide
panD 4045063 c.-782T>C upstream_gene_variant 0.93 pyrazinamide
panD 4045067 c.-786C>T upstream_gene_variant 0.93 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.93 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.93 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.85 pyrazinamide
panD 4045094 c.-813T>G upstream_gene_variant 0.86 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.86 pyrazinamide
glpK 4138361 c.1395C>T synonymous_variant 0.75 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138370 c.1386C>T synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138377 p.Val460Ala missense_variant 0.81 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138382 c.1374A>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138385 c.1371A>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138394 c.1362G>A synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138403 c.1353G>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138409 c.1347G>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138424 c.1332T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138429 c.1327T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138451 c.1305T>C synonymous_variant 0.89 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138456 c.1300C>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138459 p.Asp433Asn missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138465 p.Gly431Ser missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>A synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 0.81 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138490 c.1264_1266delGTGinsAT frameshift_variant&missense_variant 0.79 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138495 p.Gln421Glu missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138496 c.1260G>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138526 c.1230C>T synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138889 c.867G>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138898 c.858T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138910 c.846G>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138913 c.843T>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138919 c.837C>T synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138922 c.834A>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138925 c.831G>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138931 c.825G>A synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138934 c.820_822delCCAinsGG frameshift_variant&missense_variant 0.73 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138938 p.Ala273Asp missense_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138943 c.813T>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138946 c.810C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138949 c.807A>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138973 c.783T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139104 c.652T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139108 c.648G>A synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.622_624delCTAinsTG frameshift_variant&synonymous_variant 0.85 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139135 c.619_621delGATinsAC frameshift_variant&synonymous_variant 0.85 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139143 c.613T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139156 c.600C>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 0.76 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139189 c.567G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139231 c.525A>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139540 p.Ile72Met missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139545 c.211T>C synonymous_variant 0.96 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139552 c.204G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139573 c.183C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139579 c.177C>T synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139588 c.168G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139594 c.162C>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139600 c.156G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139633 c.123C>T synonymous_variant 0.99 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139651 p.His35Arg missense_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139693 c.63C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139707 p.Ile17Val missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139711 p.Asp15Glu missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139714 c.42G>A synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139718 p.Ser13Phe missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139729 c.27A>G synonymous_variant 0.89 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139733 p.Glu8Val missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4238890 c.-973G>C upstream_gene_variant 0.94 ethambutol
embC 4238896 c.-967C>G upstream_gene_variant 0.92 ethambutol
embC 4238909 c.-954C>G upstream_gene_variant 0.95 ethambutol
embC 4238912 c.-951C>T upstream_gene_variant 0.93 ethambutol
embC 4238943 c.-920G>A upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4238954 c.-909C>T upstream_gene_variant 0.91 ethambutol
embC 4238963 c.-900C>T upstream_gene_variant 0.91 ethambutol Not assoc w R
embC 4238969 c.-894A>G upstream_gene_variant 0.92 ethambutol
embC 4238972 c.-891C>G upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4238975 c.-888A>C upstream_gene_variant 0.92 ethambutol
embC 4238986 c.-877C>A upstream_gene_variant 0.9 ethambutol
embC 4238999 c.-864C>G upstream_gene_variant 0.89 ethambutol Uncertain significance
embC 4239014 c.-849C>G upstream_gene_variant 0.87 ethambutol
embC 4239027 c.-836_-834delATCinsCG upstream_gene_variant 0.81 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 0.86 ethambutol Uncertain significance
embC 4239044 c.-819G>C upstream_gene_variant 0.9 ethambutol
embC 4239059 c.-804G>C upstream_gene_variant 0.92 ethambutol
embC 4239068 c.-795A>G upstream_gene_variant 0.91 ethambutol
embC 4239071 c.-792A>G upstream_gene_variant 0.91 ethambutol Uncertain significance
embC 4239075 c.-788_-786delGCGinsAC upstream_gene_variant 0.91 ethambutol
embC 4239079 c.-784_-783delCAinsGG upstream_gene_variant 0.91 ethambutol
embC 4239089 c.-774C>G upstream_gene_variant 0.93 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 0.96 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.94 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 0.93 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 0.93 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 0.93 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 0.92 ethambutol
embC 4239189 c.-674C>T upstream_gene_variant 0.91 ethambutol
embC 4239193 c.-670G>C upstream_gene_variant 0.88 ethambutol
embC 4239305 c.-558G>C upstream_gene_variant 1.0 ethambutol
embC 4239326 c.-537C>T upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239336 c.-527T>C upstream_gene_variant 0.98 ethambutol
embC 4239344 c.-519G>C upstream_gene_variant 0.96 ethambutol
embC 4239354 c.-509A>G upstream_gene_variant 0.97 ethambutol Uncertain significance
embC 4239378 c.-485T>C upstream_gene_variant 0.97 ethambutol
embC 4239392 c.-471C>T upstream_gene_variant 0.96 ethambutol
embC 4239401 c.-462A>C upstream_gene_variant 0.98 ethambutol
embC 4239428 c.-435A>G upstream_gene_variant 0.8 ethambutol Uncertain significance
embC 4239524 c.-339C>T upstream_gene_variant 0.84 ethambutol
embC 4239530 c.-333C>G upstream_gene_variant 0.84 ethambutol
embC 4239533 c.-330T>C upstream_gene_variant 0.84 ethambutol
embC 4239539 c.-324G>A upstream_gene_variant 0.84 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 0.8 ethambutol
embC 4239569 c.-294A>G upstream_gene_variant 0.8 ethambutol Uncertain significance
embC 4239584 c.-279C>G upstream_gene_variant 0.69 ethambutol
embC 4239638 c.-225C>A upstream_gene_variant 0.73 ethambutol Uncertain significance
embC 4239641 c.-222G>C upstream_gene_variant 0.77 ethambutol
embC 4239661 c.-202A>C upstream_gene_variant 0.78 ethambutol
embC 4239663 c.-200C>G upstream_gene_variant 0.78 ethambutol
embC 4239671 c.-192C>G upstream_gene_variant 0.78 ethambutol
embC 4239674 c.-189C>G upstream_gene_variant 0.78 ethambutol
embC 4239680 c.-183C>G upstream_gene_variant 0.78 ethambutol
embC 4239688 c.-175A>G upstream_gene_variant 0.78 ethambutol
embC 4239693 c.-170_-168delGCAinsAG upstream_gene_variant 0.78 ethambutol
embC 4239696 c.-167_-166delCAinsGG upstream_gene_variant 0.78 ethambutol
embC 4239701 c.-162C>T upstream_gene_variant 0.78 ethambutol
embC 4239703 c.-160G>C upstream_gene_variant 0.78 ethambutol
embC 4240064 p.Ala68Thr missense_variant 0.91 ethambutol Uncertain significance
embC 4240069 c.207T>C synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embC 4240078 c.216A>G synonymous_variant 0.9 ethambutol
embC 4240087 c.225T>C synonymous_variant 0.94 ethambutol
embC 4240093 c.231C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4240105 p.Asp81Glu missense_variant 0.95 ethambutol
embC 4240106 c.244_246delTTGinsCC frameshift_variant&missense_variant 0.93 ethambutol
embC 4240123 c.261C>G synonymous_variant 0.94 ethambutol
embC 4240128 p.Gln89Arg missense_variant 0.94 ethambutol
embC 4240150 c.288A>G synonymous_variant 0.92 ethambutol
embC 4240151 p.Ser97Pro missense_variant 0.92 ethambutol
embC 4240171 c.309G>C synonymous_variant 0.93 ethambutol
embC 4240175 c.313T>C synonymous_variant 0.94 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.94 ethambutol
embC 4240201 c.339G>C synonymous_variant 0.91 ethambutol
embC 4240204 c.342T>C synonymous_variant 0.89 ethambutol Not assoc w R - Interim
embC 4240207 p.Lys115Asn missense_variant 0.88 ethambutol
embC 4240216 c.354T>C synonymous_variant 0.89 ethambutol
embC 4240228 c.366G>C synonymous_variant 0.77 ethambutol
embC 4240229 c.367_369delCTGinsAC frameshift_variant&missense_variant 0.76 ethambutol
embC 4240234 c.372A>G synonymous_variant 0.76 ethambutol
embC 4240237 c.375G>C synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embC 4240420 c.558T>C synonymous_variant 0.88 ethambutol
embC 4240427 p.Ser189Gly missense_variant 1.0 ethambutol
embC 4240441 c.579C>T synonymous_variant 0.97 ethambutol
embC 4240444 c.582C>G synonymous_variant 0.97 ethambutol
embC 4240471 c.609C>T synonymous_variant 0.97 ethambutol
embC 4240475 p.Ala205Ser missense_variant 0.95 ethambutol Uncertain significance
embC 4240484 c.622_624delGCGinsAA frameshift_variant&missense_variant 0.97 ethambutol
embC 4240489 c.627A>G synonymous_variant 0.95 ethambutol
embC 4240495 c.633T>C synonymous_variant 0.97 ethambutol
embC 4240512 p.Ser217Thr missense_variant 0.89 ethambutol
embC 4240516 c.654G>C synonymous_variant 0.89 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.88 ethambutol
embC 4240543 c.681G>C synonymous_variant 0.86 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.92 ethambutol Not assoc w R
embC 4240678 c.816T>G synonymous_variant 0.91 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.88 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.9 ethambutol
embC 4240699 c.837C>A synonymous_variant 0.91 ethambutol
embC 4240717 c.855T>C synonymous_variant 0.93 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embC 4240741 c.879C>T synonymous_variant 0.95 ethambutol
embC 4240777 c.915G>A synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.98 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.98 ethambutol
embC 4240795 c.933C>G synonymous_variant 0.98 ethambutol
embC 4240801 c.939C>T synonymous_variant 0.97 ethambutol
embC 4240831 c.969T>C synonymous_variant 0.99 ethambutol
embC 4240858 c.996G>A synonymous_variant 0.98 ethambutol
embC 4240859 p.Leu333Met missense_variant 0.98 ethambutol
embC 4240867 c.1005T>G synonymous_variant 0.98 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.98 ethambutol
embC 4240876 c.1014C>T synonymous_variant 0.98 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.96 ethambutol
embC 4240885 c.1023T>C synonymous_variant 0.96 ethambutol
embC 4240886 p.Ile342Val missense_variant 0.96 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.96 ethambutol Not assoc w R
embC 4240900 c.1038A>G synonymous_variant 0.98 ethambutol
embC 4240918 c.1056G>C synonymous_variant 0.97 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.9 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.92 ethambutol
embC 4240934 c.1072_1074delGTAinsTG frameshift_variant&stop_gained 0.91 ethambutol
embC 4240945 c.1083T>C synonymous_variant 0.93 ethambutol
embC 4240954 c.1092T>C synonymous_variant 0.93 ethambutol
embC 4240960 c.1098G>T synonymous_variant 0.9 ethambutol
embC 4240963 c.1101G>C synonymous_variant 0.9 ethambutol
embC 4240966 c.1104G>C synonymous_variant 0.87 ethambutol
embC 4240978 c.1116G>A synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embC 4240979 p.Thr373His missense_variant 0.89 ethambutol
embC 4240987 c.1125G>C synonymous_variant 0.91 ethambutol
embC 4240990 c.1128A>T synonymous_variant 0.91 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.95 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.96 ethambutol
embC 4241026 c.1164C>G synonymous_variant 0.96 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.97 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.97 ethambutol
embC 4241056 c.1194C>G synonymous_variant 0.97 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.98 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.98 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embC 4241153 p.Ile431Leu missense_variant 0.98 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.98 ethambutol
embC 4241167 c.1305C>G synonymous_variant 0.98 ethambutol
embC 4241185 c.1323G>C synonymous_variant 0.97 ethambutol
embC 4241197 c.1335G>C synonymous_variant 0.96 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.91 ethambutol
embC 4241361 p.Asn500Ser missense_variant 1.0 ethambutol
embC 4241365 c.1503C>G synonymous_variant 1.0 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.94 ethambutol
embC 4241383 c.1521G>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embC 4241386 c.1524C>G synonymous_variant 0.94 ethambutol
embC 4241392 c.1530G>C synonymous_variant 0.94 ethambutol
embC 4241401 c.1539C>T synonymous_variant 0.95 ethambutol
embC 4241416 c.1554C>A synonymous_variant 0.96 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.93 ethambutol
embC 4241453 c.1591_1593delATCinsGG frameshift_variant&missense_variant 0.92 ethambutol
embC 4241689 c.1827G>C synonymous_variant 0.67 ethambutol
embC 4241692 c.1830C>G synonymous_variant 0.75 ethambutol
embC 4241695 c.1833T>G synonymous_variant 0.75 ethambutol
embC 4241704 c.1842C>G synonymous_variant 0.77 ethambutol
embC 4241707 c.1845G>C synonymous_variant 0.77 ethambutol
embC 4241710 c.1848G>A synonymous_variant 0.79 ethambutol
embC 4241713 c.1851G>C synonymous_variant 0.82 ethambutol
embC 4241719 c.1857G>C synonymous_variant 0.88 ethambutol
embC 4241728 c.1866C>T synonymous_variant 0.91 ethambutol
embC 4241741 p.Val627Ile missense_variant 0.95 ethambutol Uncertain significance
embC 4241750 p.Leu630Met missense_variant 0.96 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.96 ethambutol
embC 4241761 c.1899G>C synonymous_variant 0.96 ethambutol
embC 4241788 c.1926C>T synonymous_variant 0.97 ethambutol
embC 4241791 c.1929G>C synonymous_variant 0.97 ethambutol
embC 4241797 c.1935C>T synonymous_variant 0.97 ethambutol
embC 4241809 c.1947A>G synonymous_variant 0.96 ethambutol
embC 4241818 c.1956C>T synonymous_variant 0.97 ethambutol
embC 4241821 c.1959G>A synonymous_variant 0.97 ethambutol
embC 4241824 c.1962T>C synonymous_variant 0.94 ethambutol
embC 4241836 c.1974A>C synonymous_variant 0.93 ethambutol
embC 4241845 c.1983T>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embC 4241854 c.1992A>G synonymous_variant 0.88 ethambutol
embC 4241857 c.1995C>G synonymous_variant 0.85 ethambutol
embC 4241995 c.2133C>G synonymous_variant 0.73 ethambutol
embC 4242002 c.2140T>C synonymous_variant 0.73 ethambutol
embC 4242011 p.Leu717Thr missense_variant 0.85 ethambutol
embC 4242014 c.2152_2154delTTCinsAG frameshift_variant&missense_variant 0.85 ethambutol
embC 4242022 c.2160G>C synonymous_variant 0.79 ethambutol
embC 4242024 p.Val721Ala missense_variant 0.79 ethambutol
embC 4242034 c.2172C>T synonymous_variant 0.81 ethambutol
embC 4242036 p.Gln725Leu missense_variant 0.81 ethambutol
embC 4242039 p.Ala726Gly missense_variant 0.86 ethambutol Uncertain significance
embC 4242067 c.2205G>C synonymous_variant 0.89 ethambutol
embC 4242070 c.2208T>C synonymous_variant 0.88 ethambutol
embC 4242079 c.2217T>C synonymous_variant 0.83 ethambutol
embC 4242085 c.2223A>G synonymous_variant 0.83 ethambutol
embC 4242088 c.2226G>A synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embC 4242092 c.2230_2232delTTGinsGC frameshift_variant&missense_variant 0.86 ethambutol
embC 4242095 p.Ala745Thr missense_variant 0.87 ethambutol Uncertain significance
embC 4242106 c.2244C>G synonymous_variant 0.9 ethambutol
embC 4242127 c.2265G>A synonymous_variant 0.95 ethambutol
embC 4242128 c.2266C>T synonymous_variant 0.95 ethambutol
embC 4242139 c.2277G>C synonymous_variant 0.94 ethambutol
embC 4242146 c.2284_2286delAACinsGG frameshift_variant&missense_variant 0.96 ethambutol
embC 4242151 c.2289A>C synonymous_variant 0.96 ethambutol
embC 4242161 p.Ala767Pro missense_variant 0.89 ethambutol
embC 4242166 c.2304G>A synonymous_variant 0.89 ethambutol
embC 4242171 p.Thr770Ser missense_variant 0.89 ethambutol
embC 4242175 c.2313G>T synonymous_variant 0.89 ethambutol Not assoc w R - Interim
embC 4242179 c.2317_2319delTTGinsGT frameshift_variant&missense_variant 0.94 ethambutol
embC 4242190 c.2328C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embC 4242196 c.2334A>G synonymous_variant 0.92 ethambutol
embC 4242740 c.2878_2880delCTCinsTG frameshift_variant&missense_variant 0.88 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.94 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.96 ethambutol
embC 4242773 c.2911_2913delCTGinsTA frameshift_variant&stop_gained 0.94 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.94 ethambutol
embC 4242791 c.2929_2931delGCAinsTC frameshift_variant&missense_variant 0.96 ethambutol
embC 4242794 p.Ala978Lys missense_variant 0.96 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.95 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.95 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.96 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.96 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.93 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.93 ethambutol
embA 4242871 c.-362C>T upstream_gene_variant 0.92 ethambutol
embC 4242873 p.Asp1004Val missense_variant 0.92 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embC 4242885 p.Lys1008Thr missense_variant 0.88 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.9 ethambutol
embA 4242925 c.-308C>T upstream_gene_variant 0.88 ethambutol
embA 4242928 c.-305A>T upstream_gene_variant 0.85 ethambutol
embA 4242931 c.-302G>C upstream_gene_variant 0.85 ethambutol
embA 4242934 c.-299G>C upstream_gene_variant 0.85 ethambutol
embA 4242940 c.-293T>C upstream_gene_variant 0.85 ethambutol
embC 4242941 c.3079_3081delCACinsAG frameshift_variant&missense_variant 0.85 ethambutol
embA 4242946 c.-287T>C upstream_gene_variant 0.85 ethambutol
embA 4242952 c.-281T>C upstream_gene_variant 0.89 ethambutol
embA 4242958 c.-275G>C upstream_gene_variant 0.86 ethambutol
embA 4242974 c.-259C>T upstream_gene_variant 0.92 ethambutol
embC 4242980 p.Met1040Leu missense_variant 0.97 ethambutol
embA 4242988 c.-245A>G upstream_gene_variant 0.95 ethambutol
embA 4242991 c.-242C>G upstream_gene_variant 0.95 ethambutol
embA 4243222 c.-11C>G upstream_gene_variant 0.86 ethambutol
embA 4243228 c.-5G>C upstream_gene_variant 0.86 ethambutol
embA 4243240 p.His3Leu missense_variant 0.9 ethambutol
embA 4243271 c.39A>C synonymous_variant 0.96 ethambutol
embA 4243279 p.Ala16Val missense_variant 0.94 ethambutol
embA 4243301 c.69G>C synonymous_variant 0.91 ethambutol
embA 4243304 c.72T>A synonymous_variant 0.91 ethambutol
embA 4243311 c.79C>T synonymous_variant 0.93 ethambutol
embA 4243318 p.Gly29Ala missense_variant 0.91 ethambutol
embA 4243320 c.88_90delATCinsCG frameshift_variant&missense_variant 0.91 ethambutol Uncertain significance
embA 4243334 c.102T>G synonymous_variant 0.9 ethambutol
embA 4243343 p.Asn37Lys missense_variant 0.88 ethambutol
embA 4243346 c.114A>G synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embA 4243349 c.117C>G synonymous_variant 0.85 ethambutol
embA 4243352 c.120C>G synonymous_variant 0.85 ethambutol
embA 4243362 c.130_132delTTCinsCA frameshift_variant&missense_variant 0.81 ethambutol Uncertain significance
embA 4244099 c.867T>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embA 4244102 c.870A>C synonymous_variant 0.81 ethambutol
embA 4244117 c.885G>C synonymous_variant 0.82 ethambutol
embA 4244120 c.888T>C synonymous_variant 0.85 ethambutol
embA 4244132 c.900G>C synonymous_variant 0.91 ethambutol
embA 4244154 c.922_924delACAinsC frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
embA 4244165 c.933T>G synonymous_variant 0.93 ethambutol
embA 4244170 p.Gln313Arg missense_variant 0.93 ethambutol
embA 4244178 p.Ala316Ser missense_variant 0.94 ethambutol
embA 4244198 c.966C>A synonymous_variant 0.97 ethambutol
embA 4244207 c.975C>G synonymous_variant 0.95 ethambutol
embA 4244213 c.981C>G synonymous_variant 0.88 ethambutol
embA 4244219 c.987C>G synonymous_variant 0.76 ethambutol
embA 4244228 c.996A>G synonymous_variant 0.81 ethambutol
embA 4244233 p.Ala334Gly missense_variant 0.77 ethambutol
embA 4244237 c.1005C>T synonymous_variant 0.76 ethambutol
embA 4244244 c.1012_1014delATCinsCG frameshift_variant&missense_variant 0.62 ethambutol Uncertain significance
embA 4244260 p.Val343Ala missense_variant 0.67 ethambutol
embA 4244283 p.Pro351Lys missense_variant 0.81 ethambutol
embA 4244291 c.1059G>C synonymous_variant 0.79 ethambutol
embA 4244306 c.1074G>C synonymous_variant 0.83 ethambutol
embA 4244308 p.Val359Ala missense_variant 0.83 ethambutol
embA 4244312 c.1080T>G synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embA 4244316 c.1084_1086delTTCinsCG frameshift_variant&missense_variant 0.83 ethambutol Uncertain significance
embA 4244324 c.1092T>G synonymous_variant 0.85 ethambutol
embA 4244327 c.1095T>C synonymous_variant 0.86 ethambutol
embA 4244340 p.Ser370Ala missense_variant 0.91 ethambutol
embA 4244345 c.1113C>G synonymous_variant 0.93 ethambutol
embA 4244372 c.1140T>A synonymous_variant 0.89 ethambutol
embA 4244390 c.1158G>A synonymous_variant 0.89 ethambutol
embA 4244396 c.1164T>C synonymous_variant 0.88 ethambutol
embA 4244408 c.1176G>C synonymous_variant 0.88 ethambutol
embA 4244415 c.1183T>C synonymous_variant 0.91 ethambutol
embA 4244426 c.1194G>C synonymous_variant 0.89 ethambutol
embA 4244531 c.1299G>C synonymous_variant 0.85 ethambutol
embA 4244534 c.1302T>C synonymous_variant 0.85 ethambutol
embA 4244537 c.1305T>C synonymous_variant 0.85 ethambutol Not assoc w R - Interim
embA 4244540 c.1308G>C synonymous_variant 0.86 ethambutol
embA 4244555 c.1323G>A synonymous_variant 0.86 ethambutol
embA 4244557 p.Arg442Ile missense_variant 0.86 ethambutol
embA 4244567 c.1335C>G synonymous_variant 0.86 ethambutol
embA 4244576 c.1344G>C synonymous_variant 0.85 ethambutol
embA 4244582 c.1350T>C synonymous_variant 0.83 ethambutol
embA 4244585 c.1353A>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embA 4244588 c.1356G>C synonymous_variant 0.83 ethambutol
embA 4244603 c.1371G>A synonymous_variant 0.83 ethambutol
embA 4244612 c.1380C>G synonymous_variant 0.78 ethambutol
embA 4244615 c.1383G>A synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embA 4244616 c.1384_1386delGCGinsTA frameshift_variant&stop_gained 0.78 ethambutol Uncertain significance
embA 4244619 c.1387T>C synonymous_variant 0.85 ethambutol
embA 4244645 c.1413T>C synonymous_variant 0.85 ethambutol
embA 4244648 c.1416G>C synonymous_variant 0.83 ethambutol
embA 4244649 p.Asp473Ser missense_variant 0.83 ethambutol
embA 4244663 c.1431C>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embA 4244669 c.1437G>C synonymous_variant 0.9 ethambutol
embA 4244675 c.1443A>G synonymous_variant 0.87 ethambutol
embA 4244681 c.1449A>G synonymous_variant 0.87 ethambutol Not assoc w R - Interim
embA 4244684 c.1452C>G synonymous_variant 0.87 ethambutol
embA 4244702 c.1470C>G synonymous_variant 0.92 ethambutol
embA 4244705 c.1473G>C synonymous_variant 0.95 ethambutol
embA 4244708 c.1476C>G synonymous_variant 0.95 ethambutol
embA 4244714 c.1482C>G synonymous_variant 0.95 ethambutol
embA 4244780 c.1548C>G synonymous_variant 0.91 ethambutol
embA 4244783 c.1551C>G synonymous_variant 0.91 ethambutol
embA 4244786 c.1554G>A synonymous_variant 0.87 ethambutol
embA 4244792 c.1560G>C synonymous_variant 0.9 ethambutol
embA 4244802 p.Leu524Met missense_variant 0.79 ethambutol
embA 4244805 c.1573C>T synonymous_variant 0.79 ethambutol
embA 4244822 c.1590G>A synonymous_variant 0.92 ethambutol
embA 4244823 p.Val531Met missense_variant 0.92 ethambutol
embA 4244856 p.Ala542Pro missense_variant 0.97 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.98 ethambutol
embA 4244897 c.1665T>G synonymous_variant 1.0 ethambutol
embA 4244903 c.1671G>C synonymous_variant 0.98 ethambutol
embA 4244919 c.1687_1689delCTCinsTG frameshift_variant&missense_variant 0.97 ethambutol Uncertain significance
embA 4244930 c.1698G>C synonymous_variant 0.96 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.95 ethambutol
embA 4244939 c.1707G>A synonymous_variant 0.86 ethambutol
embA 4244946 c.1714_1716delGTGinsAC frameshift_variant&missense_variant 0.82 ethambutol Uncertain significance
embA 4244960 c.1728A>G synonymous_variant 0.75 ethambutol
embA 4245032 c.1800A>G synonymous_variant 0.53 ethambutol
embA 4245035 c.1803C>A synonymous_variant 0.5 ethambutol
embA 4245047 c.1815G>C synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embA 4245051 c.1819_1821delGTGinsAC frameshift_variant&missense_variant 0.75 ethambutol Uncertain significance
embA 4245083 c.1851A>C synonymous_variant 0.92 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.92 ethambutol
embA 4245110 c.1878C>T synonymous_variant 0.92 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.95 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.94 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.94 ethambutol
embA 4245186 p.Thr652Ala missense_variant 0.94 ethambutol
embA 4245194 c.1962G>A synonymous_variant 0.94 ethambutol
embA 4245195 c.1963_1965delATCinsGG frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
embA 4245200 c.1968C>G synonymous_variant 0.94 ethambutol
embA 4245206 c.1974A>C synonymous_variant 0.96 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.96 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245224 c.1992T>C synonymous_variant 0.99 ethambutol
embA 4245248 c.2016G>A synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embA 4245257 c.2025A>G synonymous_variant 0.98 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embA 4245281 c.2049C>G synonymous_variant 0.95 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.95 ethambutol
embA 4245293 c.2061T>A synonymous_variant 0.93 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.93 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.93 ethambutol
embA 4245300 c.2068C>T synonymous_variant 0.93 ethambutol
embA 4245311 c.2079C>T synonymous_variant 0.95 ethambutol
embA 4245326 c.2094C>G synonymous_variant 0.94 ethambutol
embA 4245327 p.Ala699Leu missense_variant 0.94 ethambutol
embA 4245345 p.Met705Leu missense_variant 0.94 ethambutol
embA 4245355 p.Ala708Gly missense_variant 0.92 ethambutol
embA 4245368 c.2136T>C synonymous_variant 0.91 ethambutol
embA 4245375 c.2143_2145delCTTinsAG frameshift_variant&missense_variant 0.96 ethambutol Uncertain significance
embA 4245402 c.2170_2172delACCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245409 c.2178_2179delCA frameshift_variant 1.0 ethambutol Uncertain significance
embA 4245413 p.Ser727Arg missense_variant 1.0 ethambutol
embA 4245414 c.2182_2183insAT frameshift_variant 1.0 ethambutol Uncertain significance
embA 4245424 c.2192_2193insGCCCAG disruptive_inframe_insertion 0.96 ethambutol
embA 4245431 c.2199T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embA 4245434 c.2202G>C synonymous_variant 0.97 ethambutol
embA 4245458 c.2226G>A synonymous_variant 0.97 ethambutol
embA 4245464 c.2232C>T synonymous_variant 0.93 ethambutol
embA 4245473 c.2241C>T synonymous_variant 0.91 ethambutol
embA 4245488 c.2256G>C synonymous_variant 0.89 ethambutol
embA 4245497 c.2265C>T synonymous_variant 0.89 ethambutol
embA 4245501 c.2269_2271delGCGinsAC frameshift_variant&missense_variant 0.89 ethambutol Uncertain significance
embA 4245510 c.2278_2280delCCGinsTC frameshift_variant&missense_variant 0.88 ethambutol Uncertain significance
embA 4245524 c.2292G>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4245530 c.-984T>C upstream_gene_variant 0.87 ethambutol
embA 4245531 p.Ile767Val missense_variant 0.83 ethambutol
embA 4245535 p.Ser768Asn missense_variant 0.83 ethambutol
embB 4245539 c.-975C>G upstream_gene_variant 0.83 ethambutol
embB 4245551 c.-963A>G upstream_gene_variant 0.89 ethambutol
embA 4245566 c.2334C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4245575 c.-939C>G upstream_gene_variant 0.93 ethambutol
embB 4245594 c.-920_-919delTCinsAG upstream_gene_variant 0.96 ethambutol
embB 4245602 c.-912C>A upstream_gene_variant 0.96 ethambutol
embB 4245605 c.-909G>A upstream_gene_variant 0.96 ethambutol
embA 4245606 p.Leu792Val missense_variant 0.96 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 0.97 ethambutol
embB 4245623 c.-891G>A upstream_gene_variant 0.97 ethambutol
embB 4245662 c.-852G>C upstream_gene_variant 0.94 ethambutol
embA 4245674 c.2442A>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.95 ethambutol
embB 4245683 c.-831C>T upstream_gene_variant 0.95 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.96 ethambutol
embB 4245714 c.-800C>T upstream_gene_variant 0.94 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.92 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.93 ethambutol
embB 4245734 c.-780G>C upstream_gene_variant 0.94 ethambutol
embB 4245737 c.-777A>T upstream_gene_variant 0.94 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.94 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.9 ethambutol
embB 4245803 c.-711C>T upstream_gene_variant 0.91 ethambutol
embB 4245806 c.-708G>A upstream_gene_variant 0.9 ethambutol
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 0.9 ethambutol Uncertain significance
embB 4245812 c.-702G>T upstream_gene_variant 0.9 ethambutol
embA 4245813 p.Pro861Ala missense_variant 0.9 ethambutol
embA 4245822 p.Pro864Ala missense_variant 0.91 ethambutol
embB 4245839 c.-675G>C upstream_gene_variant 0.91 ethambutol
embA 4245843 c.2611_2613delGTTinsAC frameshift_variant&missense_variant 0.85 ethambutol Uncertain significance
embB 4245848 c.-666C>G upstream_gene_variant 0.84 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.87 ethambutol
embB 4245857 c.-657C>G upstream_gene_variant 0.9 ethambutol
embA 4245869 c.2637C>T synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4245875 c.-639G>A upstream_gene_variant 0.9 ethambutol
embB 4245887 c.-627T>C upstream_gene_variant 0.86 ethambutol
embA 4245891 p.Ile887Val missense_variant 0.86 ethambutol
embB 4245905 c.-609C>T upstream_gene_variant 0.86 ethambutol
embB 4245906 c.-608C>T upstream_gene_variant 0.86 ethambutol
embB 4245923 c.-591C>A upstream_gene_variant 0.87 ethambutol
embA 4245930 c.2698_2700delGGCinsCG frameshift_variant&missense_variant 0.8 ethambutol Uncertain significance
embA 4245935 c.2703G>C synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embA 4245942 p.Arg904Gly missense_variant 0.85 ethambutol
embB 4245953 c.-561A>G upstream_gene_variant 0.81 ethambutol
embB 4245956 c.-558G>C upstream_gene_variant 0.8 ethambutol
embA 4245965 c.2733A>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embB 4245968 c.-546T>C upstream_gene_variant 0.88 ethambutol
embA 4245978 p.Ile916Leu missense_variant 0.89 ethambutol
embB 4245983 c.-531A>G upstream_gene_variant 0.9 ethambutol
embB 4245992 c.-522C>G upstream_gene_variant 0.91 ethambutol
embB 4246004 c.-510T>C upstream_gene_variant 0.9 ethambutol
embB 4246005 c.-509C>T upstream_gene_variant 0.9 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 0.91 ethambutol
embA 4246020 p.Ala930Thr missense_variant 0.91 ethambutol
embA 4246028 c.2796G>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4246070 c.-444G>C upstream_gene_variant 0.93 ethambutol
embB 4246082 c.-432T>C upstream_gene_variant 0.93 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 0.9 ethambutol
embB 4246115 c.-399T>C upstream_gene_variant 0.92 ethambutol
embA 4246128 c.2896_2898delTCTinsAG frameshift_variant&synonymous_variant 0.89 ethambutol Uncertain significance
embA 4246138 p.Arg969Gln missense_variant 0.86 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 0.86 ethambutol
embB 4246148 c.-366G>C upstream_gene_variant 0.86 ethambutol
embB 4246151 c.-363A>C upstream_gene_variant 0.85 ethambutol
embA 4246152 p.Ala974Arg missense_variant 0.85 ethambutol
embB 4246172 c.-342C>T upstream_gene_variant 0.89 ethambutol
embB 4246184 c.-330A>C upstream_gene_variant 0.9 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.91 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.92 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.89 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.89 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.89 ethambutol
embA 4246227 c.2995_2997delATTinsGG frameshift_variant&missense_variant 0.89 ethambutol Uncertain significance
embA 4246235 c.3003G>A synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4246244 c.-270G>A upstream_gene_variant 0.93 ethambutol
embA 4246254 p.Leu1008Met missense_variant 0.91 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.91 ethambutol
embA 4246265 c.3033C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4246268 c.-246G>A upstream_gene_variant 0.91 ethambutol
embA 4246279 p.Ala1016Val missense_variant 0.94 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.94 ethambutol
embB 4246307 c.-207G>C upstream_gene_variant 0.92 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 0.94 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 0.95 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.96 ethambutol Uncertain significance
embB 4246373 c.-141T>C upstream_gene_variant 0.95 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.93 ethambutol
embA 4246398 p.Ser1056Thr missense_variant 0.95 ethambutol
embA 4246413 p.His1061Tyr missense_variant 0.94 ethambutol
embB 4246730 p.Ser73Thr missense_variant 0.93 ethambutol
embB 4246748 c.235_237delTTTinsCG frameshift_variant&missense_variant 0.92 ethambutol
embB 4246762 c.249G>T synonymous_variant 0.93 ethambutol
embB 4246768 c.255C>T synonymous_variant 0.93 ethambutol
embB 4246771 p.Asp86Glu missense_variant 0.93 ethambutol
embB 4246782 p.Ala90Gly missense_variant 0.93 ethambutol Uncertain significance
embB 4246784 p.Met91Leu missense_variant 0.93 ethambutol
embB 4246789 c.276A>G synonymous_variant 0.93 ethambutol
embB 4246792 c.279C>G synonymous_variant 0.93 ethambutol
embB 4246793 p.Ala94Gln missense_variant 0.93 ethambutol
embB 4246828 c.315A>G synonymous_variant 0.9 ethambutol
embB 4246843 c.330T>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4246844 c.331T>C synonymous_variant 0.9 ethambutol
embB 4246853 p.Leu114Met missense_variant 0.92 ethambutol
embB 4246871 p.Ala120Ser missense_variant 0.92 ethambutol
embB 4246879 c.366C>G synonymous_variant 0.88 ethambutol
embB 4246882 c.369G>C synonymous_variant 0.88 ethambutol
embB 4246894 c.381C>T synonymous_variant 0.83 ethambutol
embB 4247062 c.549G>C synonymous_variant 0.83 ethambutol
embB 4247089 c.576G>C synonymous_variant 0.95 ethambutol
embB 4247095 c.582G>A synonymous_variant 0.95 ethambutol
embB 4247104 c.591G>A synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4247113 c.600G>A synonymous_variant 0.97 ethambutol
embB 4247114 p.Ala201Lys missense_variant 0.97 ethambutol
embB 4247117 c.604_606delGTCinsCT frameshift_variant&missense_variant 0.97 ethambutol
embB 4247137 c.624C>G synonymous_variant 0.96 ethambutol
embB 4247140 c.627G>C synonymous_variant 0.96 ethambutol
embB 4247150 p.Arg213Thr missense_variant 0.89 ethambutol
embB 4247155 c.642G>A synonymous_variant 0.97 ethambutol
embB 4247179 p.Ile222Met missense_variant 0.95 ethambutol
embB 4247180 p.Ile223Val missense_variant 0.94 ethambutol
embB 4247185 c.672G>C synonymous_variant 0.95 ethambutol
embB 4247212 c.699G>C synonymous_variant 0.84 ethambutol
embB 4247213 p.Ile234Val missense_variant 0.8 ethambutol
embB 4247219 c.706T>C synonymous_variant 0.79 ethambutol
embB 4247348 p.Thr279Leu missense_variant 0.9 ethambutol
embB 4247353 c.840C>T synonymous_variant 0.9 ethambutol
embB 4247355 p.Ala281Gly missense_variant 0.9 ethambutol
embB 4247365 c.852A>C synonymous_variant 0.93 ethambutol
embB 4247370 p.Gly286Ala missense_variant 0.93 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.95 ethambutol
embB 4247398 c.885G>C synonymous_variant 0.95 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.95 ethambutol
embB 4247404 c.891G>C synonymous_variant 0.96 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.94 ethambutol
embB 4247440 c.927C>G synonymous_variant 0.94 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.95 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.95 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.95 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.96 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.95 ethambutol
embB 4247555 c.1042_1044delCTGinsAC frameshift_variant&missense_variant 0.95 ethambutol
embB 4247566 c.1053C>G synonymous_variant 0.95 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.93 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4247608 c.1095G>C synonymous_variant 0.97 ethambutol
embB 4247611 c.1098G>C synonymous_variant 0.97 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.97 ethambutol
embB 4247645 p.Glu378Thr missense_variant 0.94 ethambutol
embB 4247648 p.Ala379Ser missense_variant 0.93 ethambutol
embB 4247657 p.Pro382Ala missense_variant 0.94 ethambutol
embB 4247671 c.1158G>A synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4247679 p.Met389Thr missense_variant 0.97 ethambutol
embB 4247684 c.1171T>C synonymous_variant 0.97 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.97 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.98 ethambutol
embB 4247728 c.1215G>A synonymous_variant 0.98 ethambutol
embB 4247743 c.1230C>G synonymous_variant 0.99 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.97 ethambutol
embB 4247779 c.1266C>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 0.97 ethambutol
embB 4247800 c.1287A>C synonymous_variant 0.95 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.96 ethambutol
embB 4247816 p.Val435Ile missense_variant 0.96 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 0.96 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4247858 c.1345C>T synonymous_variant 0.96 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.94 ethambutol
embB 4247911 p.Leu466Phe missense_variant 0.93 ethambutol
embB 4247915 p.Arg468Lys missense_variant 0.89 ethambutol
embB 4247920 c.1407T>C synonymous_variant 0.89 ethambutol
embB 4247923 c.1410T>C synonymous_variant 0.91 ethambutol
embB 4247932 c.1419C>G synonymous_variant 0.93 ethambutol
embB 4247948 p.Val479Leu missense_variant 0.95 ethambutol Uncertain significance
embB 4247975 p.Val488Ile missense_variant 0.95 ethambutol Uncertain significance
embB 4247989 c.1476G>C synonymous_variant 0.95 ethambutol
embB 4248001 c.1488C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 0.94 ethambutol
embB 4248042 p.Ala510Gly missense_variant 0.96 ethambutol
embB 4248052 c.1539G>T synonymous_variant 0.95 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.95 ethambutol
embB 4248058 c.1545C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4248061 c.1548G>A synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248064 c.1551G>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.96 ethambutol
embB 4248094 c.1581C>T synonymous_variant 0.96 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.95 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.96 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.95 ethambutol
embB 4248154 c.1641G>T synonymous_variant 0.95 ethambutol
embB 4248157 c.1644A>T synonymous_variant 0.95 ethambutol
embB 4248163 c.1650G>A synonymous_variant 0.95 ethambutol
embB 4248169 c.1656C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4248175 c.1662G>A synonymous_variant 0.94 ethambutol
embB 4248178 c.1665C>T synonymous_variant 0.95 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.95 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 0.94 ethambutol
embB 4248217 c.1704C>G synonymous_variant 0.95 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 0.94 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.95 ethambutol
embB 4248266 c.1753C>T synonymous_variant 0.95 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.95 ethambutol
embB 4248280 c.1767C>G synonymous_variant 0.96 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.98 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.98 ethambutol
embB 4248334 c.1821C>G synonymous_variant 0.98 ethambutol
embB 4248349 c.1836G>A synonymous_variant 0.98 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.98 ethambutol
embB 4248361 c.1848A>G synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embB 4248379 c.1866G>A synonymous_variant 0.98 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 0.98 ethambutol
embB 4248412 p.Phe633Leu missense_variant 0.98 ethambutol
embB 4248416 p.Leu635Met missense_variant 0.97 ethambutol
embB 4248424 c.1911G>A synonymous_variant 0.97 ethambutol
embB 4248430 c.1917T>C synonymous_variant 0.97 ethambutol
embB 4248448 c.1935C>T synonymous_variant 0.96 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.96 ethambutol
embB 4248472 c.1959T>C synonymous_variant 0.97 ethambutol
embB 4248496 c.1983G>C synonymous_variant 0.96 ethambutol
embB 4248504 p.Asp664Ala missense_variant 0.96 ethambutol
embB 4248508 c.1995G>A synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248514 c.2001A>G synonymous_variant 0.96 ethambutol
embB 4248535 c.2022C>G synonymous_variant 0.93 ethambutol
embB 4248541 c.2028T>C synonymous_variant 0.88 ethambutol
embB 4248544 c.2031G>C synonymous_variant 0.86 ethambutol
embB 4248649 c.2136T>C synonymous_variant 0.73 ethambutol
embB 4248660 p.Ala716Val missense_variant 0.88 ethambutol Uncertain significance
embB 4248670 c.2157C>T synonymous_variant 0.95 ethambutol
embB 4248676 c.2163C>G synonymous_variant 0.96 ethambutol
embB 4248682 c.2169G>C synonymous_variant 0.97 ethambutol
embB 4248697 c.2184A>C synonymous_variant 0.98 ethambutol
embB 4248706 c.2193G>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embB 4248731 p.Val740Leu missense_variant 0.98 ethambutol
embB 4248742 c.2229T>C synonymous_variant 0.97 ethambutol
embB 4248757 c.2244A>C synonymous_variant 0.93 ethambutol
embB 4248964 c.2451G>C synonymous_variant 0.81 ethambutol
embB 4248967 c.2454G>C synonymous_variant 0.81 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.93 ethambutol
embB 4249348 c.2835G>C synonymous_variant 0.94 ethambutol
embB 4249360 c.2847G>C synonymous_variant 0.94 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.94 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.95 ethambutol
embB 4249381 c.2868A>C synonymous_variant 0.96 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.98 ethambutol
embB 4249429 c.2916C>G synonymous_variant 1.0 ethambutol
embB 4249432 c.2919A>G synonymous_variant 1.0 ethambutol
embB 4249433 c.2920C>T synonymous_variant 1.0 ethambutol
embB 4249444 c.2931T>C synonymous_variant 1.0 ethambutol
embB 4249447 c.2934G>C synonymous_variant 1.0 ethambutol
embB 4249453 c.2940G>C synonymous_variant 1.0 ethambutol
embB 4249456 c.2943G>C synonymous_variant 1.0 ethambutol
embB 4249459 c.2946G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249474 c.2961C>T synonymous_variant 1.0 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249487 c.2974_2976delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol
embB 4249492 c.2979C>G synonymous_variant 1.0 ethambutol
embB 4249501 c.2988C>T synonymous_variant 1.0 ethambutol
embB 4249521 p.Ala1003Val missense_variant 1.0 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.98 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.98 ethambutol Uncertain significance
embB 4249540 c.3027C>T synonymous_variant 0.98 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.98 ethambutol
embB 4249568 p.Ser1019Asn missense_variant 0.98 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.98 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.97 ethambutol
embB 4249607 p.Thr1032Val missense_variant 0.94 ethambutol
embB 4249618 c.3105C>G synonymous_variant 0.94 ethambutol
embB 4249624 c.3111C>T synonymous_variant 0.97 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.94 ethambutol
embB 4249640 c.3127T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4249648 c.3135G>C synonymous_variant 0.94 ethambutol
embB 4249654 c.3141C>T synonymous_variant 0.97 ethambutol
embB 4249657 c.3144C>G synonymous_variant 0.96 ethambutol
embB 4249663 c.3150C>G synonymous_variant 0.96 ethambutol
embB 4249666 c.3153C>T synonymous_variant 0.96 ethambutol
embB 4249669 c.3156C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4249675 c.3162C>G synonymous_variant 0.93 ethambutol
embB 4249693 c.3180T>C synonymous_variant 0.97 ethambutol
embB 4249699 c.3186T>A synonymous_variant 0.97 ethambutol
embB 4249702 c.3189C>A synonymous_variant 0.97 ethambutol
embB 4249703 c.3190C>T synonymous_variant 0.97 ethambutol
embB 4249711 c.3198G>A synonymous_variant 0.95 ethambutol
embB 4249735 c.3222T>G synonymous_variant 0.93 ethambutol
embB 4249741 c.3228C>A synonymous_variant 0.92 ethambutol
embB 4249744 c.3231G>A synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4249750 p.Glu1079Asp missense_variant 0.92 ethambutol
embB 4249751 c.3238T>C synonymous_variant 0.92 ethambutol
embB 4249774 c.3261C>A synonymous_variant 0.81 ethambutol
embB 4249775 c.3262C>T synonymous_variant 0.8 ethambutol
aftB 4267196 c.1641C>T synonymous_variant 0.7 ethambutol
aftB 4267211 c.1626C>G synonymous_variant 0.78 ethambutol
aftB 4267214 c.1623A>C synonymous_variant 0.78 ethambutol
aftB 4267235 c.1602G>C synonymous_variant 0.85 ethambutol
aftB 4267244 c.1593T>C synonymous_variant 0.88 ethambutol
aftB 4267253 c.1584T>C synonymous_variant 0.93 ethambutol
aftB 4267262 c.1575T>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
aftB 4267266 p.Ala524Gly missense_variant 0.96 ethambutol
aftB 4267268 c.1569T>C synonymous_variant 1.0 ethambutol
aftB 4267276 c.1561C>T synonymous_variant 0.96 ethambutol
aftB 4267289 p.Ala516Gln missense_variant 0.93 ethambutol
aftB 4267297 c.1540T>C synonymous_variant 0.92 ethambutol
aftB 4267298 c.1539A>G synonymous_variant 0.92 ethambutol
aftB 4267305 p.Val511Ala missense_variant 0.88 ethambutol
aftB 4267316 c.1521A>G synonymous_variant 0.77 ethambutol
aftB 4267454 c.1383C>T synonymous_variant 0.81 ethambutol
aftB 4267483 c.1354T>C synonymous_variant 0.92 ethambutol
aftB 4267484 c.1353A>G synonymous_variant 0.92 ethambutol
aftB 4267489 c.1348T>C synonymous_variant 0.95 ethambutol
aftB 4267490 c.1347G>T synonymous_variant 0.95 ethambutol
aftB 4267493 c.1344G>C synonymous_variant 0.95 ethambutol
aftB 4267499 c.1338G>C synonymous_variant 0.94 ethambutol
aftB 4267510 p.Asn443Asp missense_variant 0.94 ethambutol
aftB 4267511 c.1326C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4267517 c.1320A>C synonymous_variant 0.94 ethambutol
aftB 4267520 c.1317T>G synonymous_variant 0.96 ethambutol
aftB 4267529 c.1308T>C synonymous_variant 0.97 ethambutol
aftB 4267535 c.1302A>G synonymous_variant 0.96 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 0.97 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 0.97 ethambutol
aftB 4267580 c.1257G>A synonymous_variant 0.97 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
aftB 4267622 c.1213_1215delTCGinsAC frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
aftB 4267634 p.Arg401His missense_variant 0.93 ethambutol
aftB 4267637 c.1200C>G synonymous_variant 0.93 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4267667 c.1170A>G synonymous_variant 0.84 ethambutol
aftB 4267670 c.1167G>A synonymous_variant 0.79 ethambutol
aftB 4267685 c.1152T>C synonymous_variant 0.72 ethambutol
aftB 4267785 p.Gly351Ala missense_variant 0.8 ethambutol
aftB 4267793 c.1044C>T synonymous_variant 0.89 ethambutol
aftB 4267802 c.1035T>C synonymous_variant 0.91 ethambutol
aftB 4267805 c.1032T>C synonymous_variant 0.91 ethambutol
aftB 4267808 c.1029G>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4267826 c.1011G>C synonymous_variant 0.94 ethambutol
aftB 4267838 c.999T>C synonymous_variant 0.95 ethambutol
aftB 4267841 c.996C>T synonymous_variant 0.93 ethambutol
aftB 4267856 c.981T>C synonymous_variant 0.95 ethambutol
aftB 4267879 p.Val320Leu missense_variant 0.98 ethambutol
aftB 4267891 p.Val316Ile missense_variant 0.98 ethambutol
aftB 4267892 p.Ile315Met missense_variant 0.98 ethambutol
aftB 4267898 c.939T>C synonymous_variant 0.98 ethambutol
aftB 4267907 c.930C>G synonymous_variant 0.98 ethambutol
aftB 4267912 p.Pro309Ala missense_variant 0.97 ethambutol
aftB 4267916 c.921T>C synonymous_variant 0.97 ethambutol
aftB 4267919 c.918A>G synonymous_variant 0.97 ethambutol
aftB 4267922 c.915G>A synonymous_variant 0.97 ethambutol
aftB 4267940 c.897T>G synonymous_variant 1.0 ethambutol
aftB 4267952 c.885A>G synonymous_variant 1.0 ethambutol
aftB 4267957 p.Leu294Val missense_variant 1.0 ethambutol
aftB 4267960 p.Val293Met missense_variant 1.0 ethambutol Uncertain significance
aftB 4267961 c.876C>G synonymous_variant 1.0 ethambutol
aftB 4268081 c.756A>G synonymous_variant 0.82 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.87 ethambutol
aftB 4268105 c.732T>C synonymous_variant 0.87 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.94 ethambutol
aftB 4268134 c.703C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4268135 c.700_702delCTGinsTA frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
aftB 4268138 p.Gly233Ala missense_variant 1.0 ethambutol
aftB 4268144 c.693T>C synonymous_variant 0.94 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.91 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.89 ethambutol Not assoc w R - Interim
aftB 4268183 c.654A>C synonymous_variant 0.88 ethambutol
aftB 4268952 c.-116G>A upstream_gene_variant 0.78 ethambutol
ubiA 4268956 p.Ala293Gly missense_variant 0.82 ethambutol
aftB 4268978 c.-142C>T upstream_gene_variant 0.88 ethambutol
aftB 4268994 c.-158T>C upstream_gene_variant 0.89 ethambutol
aftB 4269000 c.-164G>A upstream_gene_variant 0.9 ethambutol
aftB 4269006 c.-170T>C upstream_gene_variant 0.9 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.91 ethambutol
aftB 4269027 c.-191C>G upstream_gene_variant 0.92 ethambutol
aftB 4269030 c.-194C>G upstream_gene_variant 0.92 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 0.92 ethambutol
aftB 4269045 c.-209G>C upstream_gene_variant 0.94 ethambutol
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 0.83 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 0.62 ethambutol
ubiA 4269131 c.703C>T synonymous_variant 0.78 ethambutol Not assoc w R - Interim
ubiA 4269139 p.Cys232Ser missense_variant 0.79 ethambutol Uncertain significance
ubiA 4269143 p.Leu231Val missense_variant 0.79 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
aftB 4269150 c.-314G>C upstream_gene_variant 0.84 ethambutol
ubiA 4269162 c.670_672delTTGinsCC frameshift_variant&missense_variant 0.88 ethambutol
ubiA 4269177 c.657G>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4269180 c.-344G>T upstream_gene_variant 0.93 ethambutol
aftB 4269195 c.-359C>T upstream_gene_variant 0.97 ethambutol
aftB 4269216 c.-380C>T upstream_gene_variant 0.94 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
ubiA 4269225 c.609C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4269231 c.-395C>T upstream_gene_variant 0.94 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 0.94 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.93 ethambutol
aftB 4269248 c.-412C>T upstream_gene_variant 0.93 ethambutol
aftB 4269261 c.-425G>A upstream_gene_variant 0.9 ethambutol
aftB 4269285 c.-449T>G upstream_gene_variant 0.76 ethambutol
aftB 4269306 c.-470T>C upstream_gene_variant 0.65 ethambutol
ubiA 4269314 p.Lys174Gln missense_variant 0.75 ethambutol
ubiA 4269327 c.505_507delAAAinsGC frameshift_variant&missense_variant 0.76 ethambutol
ubiA 4269332 p.Thr168Ala missense_variant 0.8 ethambutol
aftB 4269333 c.-497C>G upstream_gene_variant 0.8 ethambutol
ubiA 4269337 p.Val166Ala missense_variant 0.8 ethambutol
aftB 4269342 c.-506G>C upstream_gene_variant 0.74 ethambutol
aftB 4269362 c.-526T>C upstream_gene_variant 0.74 ethambutol
ubiA 4269380 p.Val152Ile missense_variant 0.74 ethambutol
aftB 4269384 c.-548C>T upstream_gene_variant 0.74 ethambutol
ubiA 4269387 p.Glu149Asp missense_variant 0.72 ethambutol Not assoc w R
ubiA 4269390 c.442_444delGTGinsAC frameshift_variant&missense_variant 0.72 ethambutol
aftB 4269555 c.-719C>G upstream_gene_variant 0.87 ethambutol
aftB 4269564 c.-728G>C upstream_gene_variant 0.96 ethambutol
aftB 4269573 c.-737A>G upstream_gene_variant 0.96 ethambutol
aftB 4269588 c.-752G>C upstream_gene_variant 0.9 ethambutol
aftB 4269591 c.-755C>T upstream_gene_variant 0.9 ethambutol
aftB 4269594 c.-758A>T upstream_gene_variant 0.9 ethambutol
aftB 4269600 c.-764C>G upstream_gene_variant 0.93 ethambutol
ubiA 4269603 c.231C>T synonymous_variant 0.93 ethambutol Not assoc w R - Interim
ubiA 4269606 c.228T>C synonymous_variant 0.9 ethambutol Not assoc w R
aftB 4269612 c.-776T>C upstream_gene_variant 0.91 ethambutol
ubiA 4269620 p.Val72Ile missense_variant 0.91 ethambutol
aftB 4269621 c.-785C>G upstream_gene_variant 0.91 ethambutol
ubiA 4269627 c.205_207delGTGinsAC frameshift_variant&missense_variant 0.91 ethambutol
aftB 4269660 c.-824C>A upstream_gene_variant 0.81 ethambutol
ubiA 4269663 c.169_171delATGinsGC frameshift_variant&missense_variant 0.78 ethambutol
aftB 4269669 c.-833G>T upstream_gene_variant 0.78 ethambutol
ubiA 4269688 p.Val49Ala missense_variant 0.81 ethambutol Uncertain significance
ubiA 4269690 c.144C>T synonymous_variant 0.81 ethambutol Not assoc w R - Interim
aftB 4269699 c.-863C>A upstream_gene_variant 0.82 ethambutol
aftB 4269705 c.-869T>C upstream_gene_variant 0.85 ethambutol
ubiA 4269710 p.Gly42Arg missense_variant 0.83 ethambutol
ubiA 4269715 p.Leu40Ala missense_variant 0.84 ethambutol
aftB 4269723 c.-887G>C upstream_gene_variant 0.87 ethambutol
aftB 4269744 c.-908G>C upstream_gene_variant 0.73 ethambutol
aftB 4269762 c.-926C>G upstream_gene_variant 0.72 ethambutol
ubiA 4269771 p.Ile21Met missense_variant 0.68 ethambutol
ethA 4326298 c.1176G>A synonymous_variant 0.88 ethionamide
ethA 4326304 c.1170C>G synonymous_variant 0.88 ethionamide
ethA 4326322 c.1152T>C synonymous_variant 0.84 ethionamide
ethA 4326331 c.1143C>G synonymous_variant 0.81 ethionamide
ethA 4326337 c.1137C>T synonymous_variant 0.81 ethionamide Not assoc w R - Interim
ethA 4326343 c.1131C>T synonymous_variant 0.84 ethionamide
ethA 4326346 c.1128C>G synonymous_variant 0.84 ethionamide
ethA 4326352 c.1122T>G synonymous_variant 0.88 ethionamide
ethA 4326380 p.Thr365Lys missense_variant 0.73 ethionamide
ethA 4326469 c.1005T>C synonymous_variant 0.81 ethionamide
ethA 4326475 c.999G>T synonymous_variant 0.81 ethionamide
ethA 4326481 c.993C>T synonymous_variant 0.81 ethionamide Not assoc w R - Interim
ethA 4326484 c.990T>A synonymous_variant 0.81 ethionamide
ethA 4326487 c.987A>C synonymous_variant 0.85 ethionamide
ethA 4326490 c.984C>T synonymous_variant 0.86 ethionamide
ethA 4326507 p.Thr323Ser missense_variant 0.88 ethionamide
ethA 4326510 p.Ala322Pro missense_variant 0.89 ethionamide
ethA 4326520 p.Glu318Asp missense_variant 0.89 ethionamide
ethA 4326523 c.951T>C synonymous_variant 0.9 ethionamide
ethA 4326535 c.939G>C synonymous_variant 0.93 ethionamide
ethR 4326556 c.-993A>G upstream_gene_variant 0.94 ethionamide
ethA 4326563 p.Ala304Gly missense_variant 0.93 ethionamide
ethR 4326565 c.-984C>A upstream_gene_variant 0.93 ethionamide
ethR 4326591 c.-958A>G upstream_gene_variant 0.91 ethionamide
ethA 4326598 c.876A>G synonymous_variant 0.92 ethionamide Not assoc w R - Interim
ethR 4326610 c.-939G>C upstream_gene_variant 0.89 ethionamide
ethR 4326613 c.-936G>A upstream_gene_variant 0.89 ethionamide
ethR 4326628 c.-921G>A upstream_gene_variant 0.83 ethionamide
ethR 4326637 c.-912T>G upstream_gene_variant 0.64 ethionamide
ethR 4326640 c.-909C>T upstream_gene_variant 0.67 ethionamide
ethR 4326730 c.-819G>C upstream_gene_variant 0.69 ethionamide
ethR 4326744 c.-805G>A upstream_gene_variant 0.69 ethionamide
ethR 4326745 c.-804C>T upstream_gene_variant 0.73 ethionamide
ethR 4326760 c.-789T>A upstream_gene_variant 0.73 ethionamide
ethA 4326767 p.Thr236Phe missense_variant 0.73 ethionamide
ethA 4326777 p.Met233Leu missense_variant 0.73 ethionamide
ethA 4326779 p.Thr232Asn missense_variant 0.73 ethionamide
ethR 4326781 c.-768C>T upstream_gene_variant 0.73 ethionamide
ethR 4326793 c.-756G>C upstream_gene_variant 0.64 ethionamide
ethA 4326874 p.Lys200Asn missense_variant 0.74 ethionamide
ethR 4326880 c.-669G>A upstream_gene_variant 0.79 ethionamide
ethR 4326886 c.-663G>A upstream_gene_variant 0.8 ethionamide
ethA 4326895 c.579G>A synonymous_variant 0.86 ethionamide Not assoc w R - Interim
ethR 4326901 c.-648C>A upstream_gene_variant 0.88 ethionamide
ethR 4326907 c.-642C>A upstream_gene_variant 0.88 ethionamide
ethR 4326913 c.-636C>G upstream_gene_variant 0.86 ethionamide
ethR 4326919 c.-630T>G upstream_gene_variant 0.86 ethionamide
ethR 4326928 c.-621G>T upstream_gene_variant 0.9 ethionamide
ethA 4326949 p.Ala175Gly missense_variant 0.91 ethionamide
ethA 4326952 p.Asp174Glu missense_variant 0.91 ethionamide
ethR 4327300 c.-249G>A upstream_gene_variant 0.89 ethionamide
ethA 4327305 p.Ser57Thr missense_variant 0.35 ethionamide
ethR 4327306 c.-243G>A upstream_gene_variant 0.5 ethionamide
ethR 4327318 c.-231T>G upstream_gene_variant 0.87 ethionamide
ethR 4327327 c.-222A>G upstream_gene_variant 0.85 ethionamide
ethR 4327330 c.-219G>A upstream_gene_variant 0.88 ethionamide
ethR 4327335 c.-214A>G upstream_gene_variant 0.88 ethionamide
ethR 4327336 c.-213A>G upstream_gene_variant 0.69 ethionamide
ethR 4327390 c.-159C>G upstream_gene_variant 0.92 ethionamide
ethR 4327396 c.-153A>G upstream_gene_variant 0.92 ethionamide
ethR 4327408 c.-141G>A upstream_gene_variant 0.93 ethionamide
ethR 4327423 c.-126G>C upstream_gene_variant 0.84 ethionamide
ethR 4327426 c.-123A>G upstream_gene_variant 0.84 ethionamide
ethR 4327432 c.-117G>A upstream_gene_variant 0.84 ethionamide
ethR 4327435 c.-114T>A upstream_gene_variant 0.8 ethionamide
ethR 4327438 c.-111A>C upstream_gene_variant 0.8 ethionamide
ethR 4327441 c.-108G>C upstream_gene_variant 0.76 ethionamide
ethA 4327449 p.Ile9Val missense_variant 0.77 ethionamide
ethR 4327453 c.-96A>G upstream_gene_variant 0.77 ethionamide
ethR 4327459 c.-90G>A upstream_gene_variant 0.71 ethionamide
ethA 4327462 c.12C>T synonymous_variant 0.71 ethionamide Not assoc w R - Interim
ethA 4327477 c.-4A>T upstream_gene_variant 0.62 ethionamide
ethA 4327671 c.-198C>G upstream_gene_variant 0.88 ethionamide
ethA 4327680 c.-207A>G upstream_gene_variant 0.93 ethionamide
ethA 4327695 c.-222A>G upstream_gene_variant 0.97 ethionamide
ethA 4327707 c.-234G>C upstream_gene_variant 0.97 ethionamide
ethA 4327710 c.-237G>T upstream_gene_variant 0.97 ethionamide
ethA 4327713 c.-240A>T upstream_gene_variant 0.97 ethionamide
ethA 4327716 c.-243G>T upstream_gene_variant 0.97 ethionamide
ethA 4327720 c.-247T>G upstream_gene_variant 0.97 ethionamide
ethA 4327765 c.-292G>A upstream_gene_variant 1.0 ethionamide
ethA 4327770 c.-297G>C upstream_gene_variant 1.0 ethionamide
ethA 4327782 c.-309C>A upstream_gene_variant 1.0 ethionamide
ethA 4328088 c.-615C>T upstream_gene_variant 0.85 ethionamide
ethR 4328097 c.549G>A synonymous_variant 0.9 ethionamide Not assoc w R - Interim
ethA 4328106 c.-633T>G upstream_gene_variant 0.9 ethionamide
ethR 4328114 p.Gly189Ala missense_variant 0.9 ethionamide
ethR 4328126 p.Ser193Cys missense_variant 0.87 ethionamide
ethA 4328130 c.-657C>T upstream_gene_variant 0.9 ethionamide
ethA 4328136 c.-663T>C upstream_gene_variant 0.9 ethionamide
ethA 4328139 c.-666G>C upstream_gene_variant 0.87 ethionamide
ethR 4328141 p.Arg198His missense_variant 0.87 ethionamide
ethA 4328151 c.-678A>G upstream_gene_variant 0.87 ethionamide
ethA 4328172 c.-699C>G upstream_gene_variant 0.85 ethionamide
ethR 4328174 p.Thr209Ser missense_variant 0.83 ethionamide
ethA 4328181 c.-708A>G upstream_gene_variant 0.8 ethionamide