TB-Profiler result

Run: ERR158583
Summary

Run ID: ERR158583

Sample name:

Date: 2024-04-15T23:34:03.989672

Number of reads: 1781558

Percentage reads mapped: 25.87

Median coverage: 33.0

Strain: La3;M.canetti;lineage2;lineage4.2;lineage4.3

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.1.2 Indo-Oceanic RD239 0.12
lineage4.3 Euro-American (LAM) None 0.08
lineage2 East-Asian RD105 0.18
lineage4.2 Euro-American None 0.18
lineage4.6.4 Euro-American None 0.23
La3 M.orygis None 0.06
M.canetti M.canetti None 0.17
lineage4.8.2 Euro-American (mainly T) RD219 0.06
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Thr437Ala Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.1dupG Assoc w R
kanamycin
cycloserine
ethionamide ethA c.1015_1017delATTinsGC Assoc w R
c.751_753delAGCinsGG Assoc w R
c.478_480delCCGinsGC Assoc w R
p.Glu39* Assoc w R
clofazimine pepQ c.865_867delCACinsAT Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.562_564delTTGinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1018_1020delGGCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1144_1146delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1270_1272delCTGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1591_1593delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2344_2346delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD c.364_366delACAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.706_708delGCAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1150_1152delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.316_318delGTGinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.865_867delCACinsAT Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsCG frameshift_variant&missense_variant 0.93 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.91 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303492 c.562_564delTTGinsCT frameshift_variant&synonymous_variant 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsAG frameshift_variant&missense_variant 0.86 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303948 c.1018_1020delGGCinsCG frameshift_variant&missense_variant 0.7 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 0.7 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304074 c.1144_1146delGCCinsTG frameshift_variant&missense_variant 0.76 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304200 c.1270_1272delCTGinsTC frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304521 c.1591_1593delCTGinsGA frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305274 c.2344_2346delTCGinsGC frameshift_variant&missense_variant 0.73 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
tlyA 1917939 c.1dupG frameshift_variant 0.86 capreomycin Assoc w R
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.91 isoniazid Assoc w R High-level resistance
pepQ 2859552 c.865_867delCACinsAT frameshift_variant&synonymous_variant 0.89 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
fbiD 3339481 c.364_366delACAinsCG frameshift_variant&missense_variant 0.73 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641248 c.706_708delGCAinsAC frameshift_variant&missense_variant 0.85 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642684 c.1150_1152delTTGinsCA frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987159 c.316_318delGTGinsAT frameshift_variant&missense_variant 0.9 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.94 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.96 ethambutol Mutation from literature
embB 4247822 p.Thr437Ala missense_variant 0.94 ethambutol Mutation from literature
ethA 4326457 c.1015_1017delATTinsGC frameshift_variant&missense_variant 0.7 ethionamide Assoc w R
ethA 4326721 c.751_753delAGCinsGG frameshift_variant&missense_variant 0.64 ethionamide Assoc w R
ethA 4326994 c.478_480delCCGinsGC frameshift_variant&missense_variant 0.73 ethionamide Assoc w R
ethA 4327359 p.Glu39* stop_gained 0.72 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 0.82 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.86 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 0.88 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 0.88 isoniazid Uncertain significance
dnaA 753 c.753C>T synonymous_variant 0.88 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.88 isoniazid
dnaA 762 c.762C>T synonymous_variant 0.88 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.93 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.94 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 0.91 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.9 isoniazid Uncertain significance
dnaA 810 c.810C>G synonymous_variant 0.9 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.9 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.94 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.95 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.95 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 849 c.849A>G synonymous_variant 0.98 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.97 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.97 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.95 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.95 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.97 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.97 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.93 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.96 isoniazid
dnaA 939 c.939C>A synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 945 c.945G>A synonymous_variant 0.94 isoniazid
dnaA 955 c.955_957delAGAinsCG frameshift_variant&synonymous_variant 0.85 isoniazid Uncertain significance
dnaA 963 c.963C>G synonymous_variant 0.83 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.83 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.83 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.83 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 987 c.987C>T synonymous_variant 0.83 isoniazid
dnaA 990 c.990A>G synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.83 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 0.85 isoniazid
dnaA 1003 c.1003C>T synonymous_variant 0.88 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.93 isoniazid
dnaA 1059 c.1059C>A synonymous_variant 0.92 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.97 isoniazid
dnaA 1083 c.1083C>T synonymous_variant 0.97 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.97 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.97 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 0.96 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1143 c.1143G>A synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 1149 c.1149C>T synonymous_variant 0.85 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.85 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.85 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.88 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.88 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 1179 c.1179G>C synonymous_variant 0.94 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.92 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 0.92 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.92 isoniazid
dnaA 1200 c.1200C>T synonymous_variant 0.89 isoniazid
dnaA 1206 c.1206G>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Thr missense_variant 0.91 isoniazid
dnaA 1222 p.Thr408Ala missense_variant 0.91 isoniazid Uncertain significance
dnaA 1245 c.1245G>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.93 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.92 isoniazid
dnaA 1281 c.1281C>G synonymous_variant 0.9 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.9 isoniazid
dnaA 1299 c.1299G>A synonymous_variant 0.9 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.89 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 0.89 isoniazid
dnaA 1315 c.1315_1317delGCAinsTG frameshift_variant&stop_gained 0.83 isoniazid Uncertain significance
dnaA 1332 c.1332A>C synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.8 isoniazid
dnaA 1350 c.1350G>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 0.76 isoniazid
dnaA 1356 c.1356T>G synonymous_variant 0.77 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.82 isoniazid
dnaA 1374 c.1374G>T synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 1375 c.1375T>C synonymous_variant 0.82 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.86 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.88 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.89 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.89 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.89 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.93 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.96 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.98 isoniazid
dnaA 1458 c.1458G>A synonymous_variant 0.95 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.95 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 1488 c.1488A>G synonymous_variant 0.88 isoniazid
dnaA 1494 c.1494C>G synonymous_variant 0.82 isoniazid
dnaA 1497 c.1497T>A synonymous_variant 0.81 isoniazid
dnaA 1498 c.1498_1500delCGCinsAG frameshift_variant&missense_variant 0.81 isoniazid Uncertain significance
gyrB 5229 c.-11G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrB 5230 c.-10T>C upstream_gene_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 5238 c.-2T>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 5254 c.15A>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5284 c.45G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5293 c.54C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5302 c.63A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5305 c.66G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5308 c.69G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5359 c.120C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 0.87 levofloxacin Uncertain significance
moxifloxacin
gyrB 5377 c.138T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5422 c.183T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5425 c.186A>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5426 p.Thr63Ala missense_variant 0.77 levofloxacin
moxifloxacin
gyrB 5431 c.192A>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 5434 c.195G>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5436 p.Asn66Ser missense_variant 0.82 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 5440 c.201A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 5449 c.210T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrB 5455 c.216T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5470 c.231C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 5485 c.246C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5488 c.249C>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5491 c.252T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 5500 c.261C>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 5502 p.Thr88Met missense_variant 0.85 levofloxacin
moxifloxacin
gyrB 5527 c.288C>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrB 5542 c.303A>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5545 c.306A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5548 c.309A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5551 c.312T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 5560 c.321C>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 5569 c.330C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 5572 c.333G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 5710 c.471C>A synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5722 c.483G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5731 c.492C>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5740 c.501G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 5743 c.504G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 5744 c.505_507delTCAinsAG frameshift_variant&missense_variant 0.86 levofloxacin Uncertain significance
moxifloxacin
gyrB 5767 c.528C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5771 p.Ala178Asn missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 5779 c.540C>T synonymous_variant 0.89 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 5782 c.543A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5788 c.549G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5791 c.552A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5812 c.573C>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5815 c.576C>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5819 c.580C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5824 c.585A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5836 c.597C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 5851 c.612G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5860 c.621C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5869 c.630C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5870 p.Glu211Gln missense_variant 0.93 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5884 c.645A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 5926 c.687G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5929 c.690G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6049 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6079 c.840C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6085 c.846C>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.94 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.96 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6421 c.-881C>T upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.71 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6801 p.Lys521Arg missense_variant 0.71 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6826 c.-476G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6886 c.-416C>T upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>T upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>A upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7151 c.1912C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7165 c.-137C>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7207 c.-95C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7219 c.-83C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7231 c.-71C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7340 p.Asp13Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7652 c.351C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7703 c.402G>A synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7715 c.414G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 7940 c.639G>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7941 p.Glu214Thr missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7958 c.657C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 7970 c.669T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7973 c.672A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7988 c.687G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7997 c.696A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8000 c.699G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8030 c.729C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8042 c.741C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8048 c.747C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8105 c.804G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsGG frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8282 c.981G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 0.85 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.99 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9065 c.1764C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9218 c.1917C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9476 c.2175G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9545 c.2244A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9551 c.2250G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9585 c.2284T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9722 c.2421C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
Rv0010c 13879 c.-321T>G upstream_gene_variant 0.82 isoniazid
Rv0010c 13891 c.-333G>C upstream_gene_variant 0.9 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.94 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.91 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.91 isoniazid
fgd1 490781 c.-2T>G upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490782 c.-1G>A upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490809 c.27A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490853 p.Ala24Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490863 c.81C>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490945 c.163C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490984 p.Leu68Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491154 p.Glu124Asp missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491265 c.483G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.83 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 0.73 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491298 c.516C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 0.76 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491331 c.549G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.72 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491453 p.Gly224Asp missense_variant 0.7 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491478 c.696G>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491487 c.705C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
mshA 575506 c.159C>T synonymous_variant 0.8 ethionamide
isoniazid
mshA 575512 c.165A>G synonymous_variant 0.77 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.9 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575545 c.198C>T synonymous_variant 0.93 ethionamide
isoniazid
mshA 575548 c.201C>A synonymous_variant 0.95 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.96 ethionamide
isoniazid
mshA 575572 c.225T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 575629 c.282A>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575633 c.286_288delGCAinsAG frameshift_variant&missense_variant 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575652 p.Arg102Gln missense_variant 0.9 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.89 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575671 c.324G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575686 c.339G>A synonymous_variant 0.9 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.95 ethionamide
isoniazid
mshA 575732 c.385_387delCTTinsTG frameshift_variant&missense_variant 0.95 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575737 c.390T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.92 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575851 c.504C>T synonymous_variant 0.94 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575878 c.531A>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575892 p.Ala182Val missense_variant 0.94 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 0.94 ethionamide
isoniazid Not assoc w R - Interim
mshA 575908 c.561A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 0.86 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.84 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 0.74 ethionamide
isoniazid
ccsA 619579 c.-312G>C upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619597 c.-294G>C upstream_gene_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 619624 c.-267C>T upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619648 c.-243C>G upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619681 c.-210G>A upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194A>C upstream_gene_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 619708 c.-183G>C upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619713 c.-178_-177delCGinsTC upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619720 c.-171C>T upstream_gene_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 619727 c.-164_-162delACGinsGC upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619734 c.-157_-156delCGinsATACCCCC upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619744 c.-147A>G upstream_gene_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 619766 c.-125A>G upstream_gene_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 619771 c.-120C>G upstream_gene_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620214 c.324C>A synonymous_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620290 p.Tyr134Asn missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620314 c.424C>T synonymous_variant 0.95 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620325 c.435G>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620404 c.514C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.92 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620487 c.597C>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>C synonymous_variant 0.78 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620545 p.Leu219Phe missense_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620571 c.681A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>A synonymous_variant 0.99 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620622 c.732G>C synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>T synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 0.96 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620760 c.870C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.95 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620829 c.939G>T synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620838 c.948C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620839 c.949C>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620847 c.957G>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620853 c.963G>T synonymous_variant 0.79 capreomycin
amikacin
kanamycin
Rv0565c 656031 c.1440A>G synonymous_variant 0.8 ethionamide
Rv0565c 656052 c.1419A>G synonymous_variant 0.77 ethionamide Not assoc w R - Interim
Rv0565c 656067 c.1404C>T synonymous_variant 0.86 ethionamide
Rv0565c 656073 p.Leu466Phe missense_variant 0.87 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 0.88 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 0.89 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.89 ethionamide
Rv0565c 656103 c.1368G>A synonymous_variant 0.88 ethionamide
Rv0565c 656112 c.1359C>A synonymous_variant 0.9 ethionamide
Rv0565c 656116 p.Lys452Arg missense_variant 0.89 ethionamide
Rv0565c 656129 p.Tyr448His missense_variant 0.91 ethionamide
Rv0565c 656131 p.Pro447Leu missense_variant 0.9 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 0.95 ethionamide
Rv0565c 656136 c.1335G>C synonymous_variant 0.95 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 0.95 ethionamide
Rv0565c 656169 c.1302G>C synonymous_variant 0.9 ethionamide
Rv0565c 656262 c.1209C>G synonymous_variant 1.0 ethionamide
Rv0565c 656277 c.1194C>T synonymous_variant 1.0 ethionamide
Rv0565c 656282 c.1189C>T synonymous_variant 0.97 ethionamide Not assoc w R - Interim
Rv0565c 656295 c.1176C>T synonymous_variant 0.97 ethionamide
Rv0565c 656301 c.1170C>T synonymous_variant 0.97 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.97 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 0.91 ethionamide
Rv0565c 656876 p.Leu199Met missense_variant 0.59 ethionamide
Rv0565c 656880 c.591C>G synonymous_variant 0.63 ethionamide
Rv0565c 656889 c.582A>G synonymous_variant 0.68 ethionamide
Rv0565c 656895 c.576G>C synonymous_variant 0.71 ethionamide
Rv0565c 656922 c.547_549delATCinsGG frameshift_variant&missense_variant 0.68 ethionamide Uncertain significance
Rv0565c 656936 p.Thr179Ala missense_variant 0.75 ethionamide
Rv0565c 656964 c.507C>G synonymous_variant 0.8 ethionamide
Rv0565c 656973 c.498A>G synonymous_variant 0.81 ethionamide
Rv0565c 657023 p.Glu150Gln missense_variant 0.75 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 0.71 ethionamide
Rv0565c 657066 c.405C>T synonymous_variant 0.67 ethionamide Not assoc w R - Interim
Rv0565c 657070 p.Tyr134Cys missense_variant 0.67 ethionamide
Rv0565c 657072 p.His133Gln missense_variant 0.67 ethionamide
Rv0565c 657088 p.Asn128Gly missense_variant 0.57 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 0.87 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.93 ethionamide
Rv0565c 657196 p.Asp92Thr missense_variant 0.93 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 0.91 ethionamide
Rv0565c 657207 c.264G>A synonymous_variant 0.92 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 0.92 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.92 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.92 ethionamide Uncertain significance
Rv0565c 657243 c.228C>A synonymous_variant 0.92 ethionamide
Rv0565c 657267 c.202_204delTCGinsAGC synonymous_variant 0.91 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.98 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.96 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.91 ethionamide
Rv0565c 657340 p.Ala44Glu missense_variant 0.69 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 0.71 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.67 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.67 ethionamide
Rv0565c 657560 c.-90G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657563 c.-93T>C upstream_gene_variant 0.92 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 0.94 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.96 ethionamide
Rv0565c 657587 c.-117C>T upstream_gene_variant 0.94 ethionamide
Rv0565c 657590 c.-120G>C upstream_gene_variant 0.95 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 0.96 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.97 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsAT upstream_gene_variant 0.94 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.97 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.97 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.96 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.93 ethionamide
hadA 731687 c.-243G>C upstream_gene_variant 0.95 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 0.95 isoniazid
hadA 731693 c.-237_-236insGTTTGACACCAGAT upstream_gene_variant 0.95 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.95 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.97 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.94 isoniazid
hadA 731738 c.-192G>T upstream_gene_variant 0.95 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.93 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.91 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.92 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 0.93 isoniazid
hadA 731837 c.-93C>T upstream_gene_variant 0.87 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.9 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.86 isoniazid
hadA 731858 c.-72G>A upstream_gene_variant 0.87 isoniazid
hadA 732214 c.285A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
hadA 732223 c.294G>T synonymous_variant 0.86 isoniazid
hadA 732226 c.297G>C synonymous_variant 0.87 isoniazid
hadA 732229 c.300C>T synonymous_variant 0.88 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.92 isoniazid
hadA 732247 c.318C>T synonymous_variant 0.94 isoniazid
hadA 732250 c.321C>G synonymous_variant 0.94 isoniazid
hadA 732263 p.Val112Met missense_variant 0.94 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.91 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.94 isoniazid
hadA 732322 p.Glu131Asp missense_variant 0.94 isoniazid
hadA 732329 c.400_402delCTCinsAT frameshift_variant&missense_variant 0.94 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 0.94 isoniazid
hadA 732361 c.432C>T synonymous_variant 0.94 isoniazid
hadA 732376 c.447T>C synonymous_variant 0.92 isoniazid
hadA 732378 c.449_450insGGA disruptive_inframe_insertion 0.91 isoniazid
hadA 732381 p.Glu151Val missense_variant 0.94 isoniazid
hadA 732391 c.462T>A synonymous_variant 0.94 isoniazid
nusG 734075 c.-179T>G upstream_gene_variant 0.91 rifampicin
nusG 734090 c.-164G>A upstream_gene_variant 0.92 rifampicin
nusG 734093 c.-161A>G upstream_gene_variant 0.92 rifampicin
nusG 734102 c.-152G>T upstream_gene_variant 0.96 rifampicin
nusG 734110 c.-144_-143delAAinsGG upstream_gene_variant 0.96 rifampicin
nusG 734118 c.-136_-134delCTTinsAC upstream_gene_variant 0.96 rifampicin
nusG 734135 c.-119G>A upstream_gene_variant 0.96 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 0.94 rifampicin
nusG 734150 c.-104G>T upstream_gene_variant 0.91 rifampicin
nusG 734337 c.84G>C synonymous_variant 0.67 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.83 rifampicin
nusG 734361 c.108C>T synonymous_variant 0.86 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.88 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.9 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.96 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.96 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.96 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.99 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.99 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.94 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.96 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.96 rifampicin
nusG 734616 c.363C>A synonymous_variant 0.94 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.95 rifampicin
nusG 734631 c.378G>A synonymous_variant 0.96 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.97 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.95 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.94 rifampicin
nusG 734661 c.408A>C synonymous_variant 0.94 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.92 rifampicin
nusG 734670 c.417G>A synonymous_variant 0.92 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.91 rifampicin
nusG 734680 p.Ala143Ser missense_variant 0.9 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.87 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.88 rifampicin
nusG 734712 c.459G>C synonymous_variant 0.87 rifampicin
nusG 734718 c.465G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 0.85 rifampicin
nusG 734722 p.Thr157Ala missense_variant 0.85 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.87 rifampicin
nusG 734733 c.480T>A synonymous_variant 0.87 rifampicin
nusG 734736 c.483C>G synonymous_variant 0.89 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.92 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.92 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.93 rifampicin
nusG 734769 c.516G>A synonymous_variant 0.94 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.93 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.93 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.95 rifampicin
nusG 734793 c.540C>T synonymous_variant 0.95 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.96 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.94 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.92 rifampicin
nusG 734874 c.621G>A synonymous_variant 0.95 rifampicin
nusG 734880 c.627C>T synonymous_variant 0.94 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.93 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.86 rifampicin
nusG 734928 c.675A>G synonymous_variant 0.63 rifampicin
rpoB 759583 c.-224T>G upstream_gene_variant 0.9 rifampicin
rpoB 759587 c.-220T>A upstream_gene_variant 0.9 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 0.94 rifampicin
rpoB 759635 c.-172C>T upstream_gene_variant 0.97 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.98 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoB 759661 c.-146G>C upstream_gene_variant 0.99 rifampicin
rpoB 759670 c.-137C>T upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.97 rifampicin
rpoB 759675 c.-132T>C upstream_gene_variant 0.97 rifampicin
rpoB 759676 c.-131A>G upstream_gene_variant 0.97 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 0.94 rifampicin
rpoB 759715 c.-92_-91delGAinsT upstream_gene_variant 0.89 rifampicin
rpoB 759725 c.-82A>C upstream_gene_variant 0.88 rifampicin
rpoB 759732 c.-75_-74insT upstream_gene_variant 0.84 rifampicin
rpoB 759835 p.Ala10Asp missense_variant 0.93 rifampicin
rpoB 759845 c.39T>C synonymous_variant 0.93 rifampicin
rpoB 759846 p.Ser14Ala missense_variant 0.93 rifampicin
rpoB 759850 p.Pro15Gln missense_variant 0.88 rifampicin
rpoB 759869 c.63C>T synonymous_variant 0.94 rifampicin
rpoB 759872 c.66G>A synonymous_variant 0.94 rifampicin
rpoB 759875 c.69T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 759877 p.Asn24Ser missense_variant 0.94 rifampicin
rpoB 759884 c.78A>G synonymous_variant 0.92 rifampicin
rpoB 759896 c.90A>T synonymous_variant 0.94 rifampicin
rpoB 759899 c.93C>T synonymous_variant 0.95 rifampicin
rpoB 759905 c.99C>T synonymous_variant 0.96 rifampicin
rpoB 759914 c.108T>C synonymous_variant 0.96 rifampicin
rpoB 759920 c.114G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 759929 c.123A>G synonymous_variant 0.94 rifampicin
rpoB 759932 c.126T>G synonymous_variant 0.94 rifampicin
rpoB 759944 c.138A>G synonymous_variant 0.93 rifampicin
rpoB 759945 c.139_141delCTCinsTG frameshift_variant&missense_variant 0.93 rifampicin
rpoB 759956 c.150C>G synonymous_variant 0.96 rifampicin
rpoB 759965 c.159T>C synonymous_variant 0.96 rifampicin
rpoB 759989 c.183G>C synonymous_variant 0.96 rifampicin
rpoB 759991 p.Pro62Gln missense_variant 0.96 rifampicin
rpoB 760059 p.Tyr85Asp missense_variant 1.0 rifampicin
rpoB 760067 c.261G>C synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>A synonymous_variant 1.0 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.97 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.96 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.97 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 0.98 rifampicin
rpoB 760196 c.390C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.99 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.99 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.99 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.97 rifampicin
rpoB 760409 c.603C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 0.97 rifampicin
rpoB 760415 c.609C>G synonymous_variant 0.97 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 0.95 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 0.92 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.94 rifampicin
rpoB 760528 p.Gln241Arg missense_variant 0.94 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.93 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.96 rifampicin Uncertain significance
rpoB 760577 c.771G>A synonymous_variant 0.98 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.97 rifampicin
rpoB 760604 c.798G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 0.98 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>A synonymous_variant 0.96 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760664 c.858G>C synonymous_variant 0.89 rifampicin
rpoB 760670 c.864G>C synonymous_variant 0.88 rifampicin
rpoB 760673 c.867G>A synonymous_variant 0.87 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.73 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760805 c.999G>C synonymous_variant 0.82 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.91 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.98 rifampicin
rpoB 760859 c.1053T>G synonymous_variant 0.99 rifampicin
rpoB 760868 c.1062C>G synonymous_variant 0.99 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.97 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.97 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.93 rifampicin
rpoB 760994 c.1188G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.93 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>A synonymous_variant 0.92 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761066 c.1260G>C synonymous_variant 0.94 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 0.93 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.92 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.93 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.96 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 0.96 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.93 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.94 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 0.94 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.94 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761346 p.Val514Ile missense_variant 0.95 rifampicin
rpoB 761384 c.1578C>G synonymous_variant 0.85 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.92 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 0.91 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.92 rifampicin
rpoB 761438 c.1632G>T synonymous_variant 0.92 rifampicin
rpoB 761441 p.Asp545Glu missense_variant 0.92 rifampicin Uncertain significance
rpoB 761444 c.1638T>C synonymous_variant 0.85 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.88 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 0.92 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.94 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.94 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 0.97 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 0.96 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.97 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 0.97 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.97 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.95 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.95 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.95 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.95 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.94 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 0.95 rifampicin
rpoB 761735 c.1929C>G synonymous_variant 0.91 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.98 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.95 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.95 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.97 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.97 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.95 rifampicin
rpoB 761822 c.2016C>G synonymous_variant 0.93 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.89 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.78 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.77 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 0.77 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 0.81 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.81 rifampicin
rpoB 761876 c.2070C>A synonymous_variant 0.85 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.9 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.9 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.9 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.9 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 0.9 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.91 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.92 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 0.93 rifampicin
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 0.92 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762071 c.2265C>T synonymous_variant 0.96 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.97 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 0.97 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.96 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.98 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 0.99 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 0.99 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.98 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.98 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.98 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>G synonymous_variant 0.98 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.95 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.94 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.91 rifampicin
rpoB 762369 c.2563_2565delTTGinsCT frameshift_variant&synonymous_variant 0.91 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.91 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.92 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.96 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.95 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.95 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.95 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.96 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 0.92 rifampicin
rpoB 762489 p.Val895Gln missense_variant 0.91 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.92 rifampicin
rpoC 762518 c.-852C>G upstream_gene_variant 0.93 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.92 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.93 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.93 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.89 rifampicin
rpoC 762557 c.-813G>C upstream_gene_variant 0.89 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.88 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.88 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.85 rifampicin
rpoC 762599 c.-771T>A upstream_gene_variant 0.74 rifampicin
rpoC 762605 c.-765T>C upstream_gene_variant 0.68 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 0.67 rifampicin
rpoC 762617 c.-753C>G upstream_gene_variant 0.46 rifampicin
rpoC 762710 c.-660G>T upstream_gene_variant 0.81 rifampicin
rpoB 762740 c.2934G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762749 c.-621C>G upstream_gene_variant 0.93 rifampicin
rpoC 762758 c.-612G>A upstream_gene_variant 0.93 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 0.93 rifampicin Uncertain significance
rpoC 762764 c.-606G>A upstream_gene_variant 0.96 rifampicin
rpoC 762765 c.-605C>T upstream_gene_variant 0.96 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 0.97 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 0.96 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762813 c.3007_3009delATGinsGC frameshift_variant&missense_variant 0.93 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 0.96 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>T upstream_gene_variant 0.97 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.98 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 0.97 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.98 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.99 rifampicin
rpoB 763193 c.3387C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.97 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.97 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.92 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.92 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.93 rifampicin Uncertain significance
rpoC 763375 c.6C>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.96 rifampicin
rpoC 763430 c.61A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763435 c.66A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 0.95 rifampicin
rpoC 763561 c.192G>A synonymous_variant 0.93 rifampicin
rpoC 763600 c.231C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.95 rifampicin
rpoC 763618 c.249C>A synonymous_variant 0.96 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 0.95 rifampicin
rpoC 763639 c.270G>A synonymous_variant 0.95 rifampicin
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 0.93 rifampicin
rpoC 763666 c.297G>A synonymous_variant 0.93 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.94 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.94 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.92 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.95 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.96 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.98 rifampicin
rpoC 763771 c.402C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.98 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.97 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763819 c.450G>C synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.98 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.94 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.94 rifampicin
rpoC 763916 p.Glu183Gln missense_variant 0.96 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.98 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.98 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.98 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.99 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.99 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.99 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.97 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.97 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.97 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.97 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.97 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.98 rifampicin
rpoC 764101 c.732C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.99 rifampicin
rpoC 764119 c.750G>A synonymous_variant 0.99 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.98 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 0.95 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.92 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.92 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.92 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.94 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.94 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.95 rifampicin
rpoC 764272 c.903G>T synonymous_variant 0.95 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.94 rifampicin
rpoC 764317 c.948C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>T synonymous_variant 0.93 rifampicin
rpoC 764347 c.978G>C synonymous_variant 0.94 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.92 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>A synonymous_variant 0.85 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.91 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.88 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.88 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.88 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.89 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.96 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.96 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>A synonymous_variant 0.98 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 0.96 rifampicin
rpoC 764536 c.1167G>A synonymous_variant 0.96 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.95 rifampicin
rpoC 764587 c.1218C>G synonymous_variant 0.97 rifampicin
rpoC 764648 c.1279C>A synonymous_variant 0.98 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 0.97 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.98 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764674 c.1305G>A synonymous_variant 0.98 rifampicin
rpoC 764681 c.1312C>T synonymous_variant 0.98 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.96 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>C synonymous_variant 0.97 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 0.96 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.96 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.97 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 0.97 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 0.97 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764918 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.96 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765067 c.1698G>C synonymous_variant 0.87 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.86 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 0.86 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 0.83 rifampicin
rpoC 765088 c.1719G>C synonymous_variant 0.83 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765100 c.1731G>C synonymous_variant 0.8 rifampicin
rpoC 765103 c.1734G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765115 c.1746G>A synonymous_variant 0.8 rifampicin
rpoC 765122 c.1753C>T synonymous_variant 0.79 rifampicin
rpoC 765208 c.1839T>C synonymous_variant 0.77 rifampicin
rpoC 765217 c.1848C>G synonymous_variant 0.82 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 0.85 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 0.87 rifampicin
rpoC 765245 c.1877_1878insGCT disruptive_inframe_insertion 0.83 rifampicin
rpoC 765249 p.Leu627Ser missense_variant 0.78 rifampicin
rpoC 765250 c.1882_1884delAGC conservative_inframe_deletion 0.81 rifampicin
rpoC 765287 c.1918C>T synonymous_variant 0.77 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.74 rifampicin
rpoC 765296 c.1927_1929delCCGinsTT frameshift_variant&missense_variant 0.74 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.7 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>G synonymous_variant 0.53 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.47 rifampicin Uncertain significance
rpoC 765340 p.Gln657His missense_variant 0.65 rifampicin
rpoC 765349 p.Asp660Glu missense_variant 0.75 rifampicin
rpoC 765350 c.1981_1983delGCGinsCC frameshift_variant&missense_variant 0.75 rifampicin
rpoC 765358 p.Met663Ile missense_variant 0.81 rifampicin Uncertain significance
rpoC 765364 p.Glu665Asp missense_variant 0.81 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 0.82 rifampicin
rpoC 765376 c.2007C>G synonymous_variant 0.89 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.89 rifampicin Uncertain significance
rpoC 765395 c.2026C>T synonymous_variant 0.91 rifampicin
rpoC 765405 p.Leu679Pro missense_variant 0.96 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 0.94 rifampicin
rpoC 765430 c.2061G>A synonymous_variant 0.97 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.97 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 0.98 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765526 c.2157C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>A synonymous_variant 0.98 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.98 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.97 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.96 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.95 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 0.95 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 0.95 rifampicin
rpoC 765610 c.2241C>T synonymous_variant 0.94 rifampicin
rpoC 765612 p.His748Arg missense_variant 0.94 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.96 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765676 c.2307G>A synonymous_variant 0.97 rifampicin
rpoC 765688 c.2319G>C synonymous_variant 0.97 rifampicin
rpoC 765689 c.2320C>T synonymous_variant 0.97 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 0.97 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 0.95 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 0.97 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 0.97 rifampicin
rpoC 765757 c.2388C>T synonymous_variant 0.97 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.97 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.97 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.95 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.95 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>A synonymous_variant 0.99 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.98 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.98 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.98 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 0.98 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 0.97 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.96 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 0.93 rifampicin
rpoC 766070 c.2701C>T synonymous_variant 0.89 rifampicin Not assoc w R
rpoC 766082 p.Ala905Gln missense_variant 0.78 rifampicin
rpoC 766089 c.2720_2721delACinsGGGTTGATGGGCAA missense_variant&conservative_inframe_insertion 0.58 rifampicin
rpoC 766092 p.Gly908Val missense_variant 0.58 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.58 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 0.4 rifampicin
rpoC 766249 c.2880C>A synonymous_variant 0.52 rifampicin
rpoC 766255 c.2886G>T synonymous_variant 0.71 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.82 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.86 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.88 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 0.89 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766306 c.2937C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.9 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.9 rifampicin
rpoC 766324 c.2955C>T synonymous_variant 0.94 rifampicin
rpoC 766351 c.2982C>G synonymous_variant 0.98 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.98 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.98 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.99 rifampicin
rpoC 766397 c.3028C>T synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766417 c.3048C>T synonymous_variant 0.99 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.99 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.99 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.97 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.99 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766519 c.3150C>A synonymous_variant 0.98 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.97 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.96 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.96 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.95 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 0.92 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 0.95 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.95 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.92 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.93 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.95 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 0.96 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.99 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.96 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.96 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.96 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.98 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.96 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 0.96 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.95 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.95 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.95 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.95 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.96 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766795 c.3426C>T synonymous_variant 0.99 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.99 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.98 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.98 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.98 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766918 c.3549C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.97 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.97 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.95 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.98 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>T synonymous_variant 0.93 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.93 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.93 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.94 rifampicin
rpoC 767206 c.3837C>A synonymous_variant 0.93 rifampicin
rpoC 767209 c.3840T>G synonymous_variant 0.93 rifampicin
rpoC 767212 c.3843G>C synonymous_variant 0.92 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.9 rifampicin
rpoC 767275 c.3906T>A synonymous_variant 0.89 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.89 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.89 rifampicin
rpoC 767287 c.3918G>A synonymous_variant 0.89 rifampicin
rpoC 767317 c.3948C>G synonymous_variant 0.7 rifampicin
rpsL 781571 c.12C>T synonymous_variant 0.88 streptomycin
rpsL 781586 c.27C>A synonymous_variant 0.94 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.95 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.97 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.93 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.95 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.94 streptomycin
rpsL 781664 c.105C>T synonymous_variant 0.94 streptomycin
rpsL 781667 c.108C>G synonymous_variant 0.94 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.96 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.96 streptomycin
rpsL 781721 c.162C>G synonymous_variant 0.96 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.96 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.97 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.96 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.92 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.93 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.91 streptomycin
rpsL 781847 c.288G>A synonymous_variant 0.92 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.91 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.92 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.92 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.93 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.93 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.91 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.93 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.95 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.95 streptomycin Uncertain significance
rplC 800209 c.-600C>T upstream_gene_variant 0.95 linezolid
rplC 800224 c.-585G>C upstream_gene_variant 0.93 linezolid
rplC 800225 c.-584T>C upstream_gene_variant 0.93 linezolid
rplC 800237 c.-572T>C upstream_gene_variant 0.92 linezolid
rplC 800244 c.-565A>G upstream_gene_variant 0.92 linezolid
rplC 800267 c.-542T>C upstream_gene_variant 0.91 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 0.91 linezolid
rplC 800278 c.-531A>G upstream_gene_variant 0.89 linezolid
rplC 800285 c.-524_-523insC upstream_gene_variant 0.92 linezolid
rplC 800295 c.-513_-502delCTTGAAATTGAT upstream_gene_variant 0.71 linezolid
rplC 800311 c.-498delGinsCT upstream_gene_variant 0.71 linezolid
rplC 800321 c.-488T>C upstream_gene_variant 0.79 linezolid
rplC 800341 c.-468G>C upstream_gene_variant 0.82 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.99 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.99 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.99 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.98 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.98 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 0.98 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.98 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.98 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.95 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.97 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.94 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.94 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.94 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.94 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.94 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.95 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.97 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.96 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.96 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 0.94 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 0.94 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 0.95 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 0.95 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 0.95 linezolid
rplC 800817 c.9A>C synonymous_variant 0.95 linezolid
rplC 800844 c.36T>C synonymous_variant 0.97 linezolid
rplC 800865 c.57A>G synonymous_variant 0.96 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.96 linezolid
rplC 800877 c.69A>C synonymous_variant 0.98 linezolid
rplC 800907 c.99C>G synonymous_variant 0.96 linezolid
rplC 800913 c.105G>C synonymous_variant 0.96 linezolid
rplC 800916 c.108A>T synonymous_variant 0.96 linezolid
rplC 800922 c.114C>G synonymous_variant 0.96 linezolid
rplC 800934 c.126C>G synonymous_variant 0.96 linezolid
rplC 800937 c.129A>G synonymous_variant 0.96 linezolid
rplC 800946 c.138T>G synonymous_variant 0.95 linezolid
rplC 800949 c.141T>C synonymous_variant 0.95 linezolid
rplC 800955 c.147C>G synonymous_variant 0.94 linezolid
rplC 800958 c.150G>A synonymous_variant 0.94 linezolid
rplC 800970 c.162T>C synonymous_variant 0.92 linezolid Not assoc w R - Interim
rplC 800976 c.168G>A synonymous_variant 0.94 linezolid
rplC 800982 c.174C>T synonymous_variant 0.93 linezolid
rplC 801117 c.309G>C synonymous_variant 0.8 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801144 c.336C>G synonymous_variant 0.94 linezolid
rplC 801147 c.339T>C synonymous_variant 0.96 linezolid
rplC 801153 c.345G>C synonymous_variant 0.96 linezolid
rplC 801174 c.366T>C synonymous_variant 0.95 linezolid
rplC 801201 c.393C>T synonymous_variant 0.96 linezolid
rplC 801210 c.402T>C synonymous_variant 0.96 linezolid
rplC 801216 c.408C>A synonymous_variant 0.96 linezolid
rplC 801219 c.411C>T synonymous_variant 0.96 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.97 linezolid
rplC 801246 c.438C>G synonymous_variant 0.98 linezolid
rplC 801252 c.444G>C synonymous_variant 0.98 linezolid
rplC 801267 c.459A>T synonymous_variant 0.96 linezolid
rplC 801276 c.468G>C synonymous_variant 0.97 linezolid
rplC 801297 c.489C>T synonymous_variant 0.96 linezolid Not assoc w R - Interim
rplC 801312 c.504G>C synonymous_variant 0.96 linezolid
rplC 801339 c.531T>G synonymous_variant 0.96 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.96 linezolid
rplC 801348 c.540T>G synonymous_variant 0.96 linezolid
rplC 801357 c.549T>C synonymous_variant 0.95 linezolid
rplC 801372 c.564G>A synonymous_variant 0.97 linezolid
rplC 801385 c.577C>T synonymous_variant 0.96 linezolid
rplC 801396 c.588T>C synonymous_variant 0.96 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801417 c.609T>C synonymous_variant 0.95 linezolid
rplC 801423 c.615G>C synonymous_variant 0.95 linezolid
rplC 801426 c.618C>G synonymous_variant 0.95 linezolid
rplC 801438 c.630T>C synonymous_variant 0.82 linezolid
rplC 801447 c.639A>G synonymous_variant 0.8 linezolid
Rv1129c 1253450 p.Ser362Asn missense_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253461 c.1074G>C synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253464 c.1069_1071delAGCinsTCT synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253476 c.1059G>A synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253482 c.1053G>C synonymous_variant 0.69 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253491 c.1044A>C synonymous_variant 0.82 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253494 c.1041G>A synonymous_variant 0.82 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253509 c.1026C>A synonymous_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253512 p.Lys341Ser missense_variant 0.75 moxifloxacin
levofloxacin
rifampicin
isoniazid
fbiC 1303431 c.501T>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303467 c.537C>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303479 c.549G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303591 c.661C>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303632 c.702T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303768 p.Ser280Ala missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303956 p.Glu342Asp missense_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>T synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304055 p.Asp375Glu missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 0.73 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304059 c.1129C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304091 c.1161C>T synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304112 c.1182G>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304120 p.Lys397Arg missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304124 c.1194C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304164 p.Gly412Arg missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304181 c.1251G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304217 p.Asn429Lys missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304502 c.1572G>A synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304511 c.1581C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304598 c.1668C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304649 c.1719C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304679 c.1749G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304715 c.1785G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304809 p.Ser627Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.91 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305001 p.Ile691Val missense_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1305027 c.2097G>A synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1305036 c.2106G>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1305051 c.2121G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305088 p.Val720Ile missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305162 c.2232C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305165 c.2235G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305192 c.2262C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305219 p.His763Gln missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>A synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305375 c.2445C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
sigE 1364796 c.384G>A synonymous_variant 0.97 pyrazinamide
sigE 1364802 c.390C>G synonymous_variant 0.95 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.94 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 0.94 pyrazinamide Uncertain significance
sigE 1364839 c.427T>C synonymous_variant 0.96 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 0.96 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.96 pyrazinamide
sigE 1364866 c.454_456delGCTinsAC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
sigE 1364889 c.477A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 0.97 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
sigE 1364919 c.507T>C synonymous_variant 0.97 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.97 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.96 pyrazinamide
sigE 1364955 c.543G>T synonymous_variant 0.95 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.94 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
sigE 1364967 c.555C>T synonymous_variant 0.93 pyrazinamide
sigE 1364968 c.556C>T synonymous_variant 0.93 pyrazinamide
sigE 1364980 c.568_570delTTGinsCC frameshift_variant&missense_variant 0.93 pyrazinamide Uncertain significance
sigE 1364984 p.Ala191Asp missense_variant 0.93 pyrazinamide
Rv1258c 1406270 c.1071C>T synonymous_variant 0.95 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406291 c.1050G>A synonymous_variant 0.95 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406297 c.1044A>G synonymous_variant 0.95 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406314 p.His343Tyr missense_variant 0.93 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406315 p.Gln342His missense_variant 0.93 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406318 c.1021_1023delGCAinsCG frameshift_variant&synonymous_variant 0.93 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
Rv1258c 1406327 c.1014G>C synonymous_variant 0.87 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406330 c.1011G>A synonymous_variant 0.87 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406333 p.Ile336Met missense_variant 0.87 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406345 c.996T>C synonymous_variant 0.81 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406351 c.990G>C synonymous_variant 0.76 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406360 c.981C>G synonymous_variant 0.64 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406553 p.Ala263Val missense_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406556 p.Trp262Ser missense_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406558 c.783T>C synonymous_variant 0.85 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406567 p.Val258Ala missense_variant 0.73 streptomycin
isoniazid
pyrazinamide
Rv1258c 14065