TB-Profiler result

Run: SRR10809074
Summary

Run ID: SRR10809074

Sample name:

Date: 2024-03-25T21:24:19.106859

Number of reads: 413565

Percentage reads mapped: 13.71

Median coverage: 2.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3.1.2.2 East-African-Indian RD750 0.09
lineage4 Euro-American None 0.98
lineage1.2.1.2.1 Indo-Oceanic RD239 0.11
lineage4.9 Euro-American (H37Rv-like) None 0.88
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.451_453delGTCinsCG Assoc w R High-level resistance
c.343_345delATCinsGG Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.766_768delGCTinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.87 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491548 c.766_768delGCTinsCC frameshift_variant&missense_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155659 c.451_453delGTCinsCG frameshift_variant&missense_variant 0.86 isoniazid Assoc w R High-level resistance
katG 2155767 c.343_345delATCinsGG frameshift_variant&missense_variant 0.91 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 597 c.597C>G synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>G synonymous_variant 0.85 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.85 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.86 isoniazid
dnaA 633 c.633T>C synonymous_variant 0.89 isoniazid
dnaA 645 c.645A>G synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 648 c.648C>T synonymous_variant 0.88 isoniazid
dnaA 654 c.654A>G synonymous_variant 0.88 isoniazid
dnaA 663 c.663A>C synonymous_variant 0.89 isoniazid
dnaA 666 c.666C>G synonymous_variant 0.89 isoniazid
dnaA 681 c.681G>T synonymous_variant 0.89 isoniazid
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 0.89 isoniazid Uncertain significance
dnaA 690 c.690G>C synonymous_variant 0.89 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.89 isoniazid
dnaA 699 c.699G>C synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 702 c.702C>G synonymous_variant 0.89 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.89 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.89 isoniazid
dnaA 717 c.717C>A synonymous_variant 0.95 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 767 p.Val256Ala missense_variant 1.0 isoniazid
dnaA 769 c.769_771delGCAinsTG frameshift_variant&stop_gained 1.0 isoniazid Uncertain significance
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 780 c.780C>G synonymous_variant 1.0 isoniazid
dnaA 783 c.783C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 799 c.799_801delGTGinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.92 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.92 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.92 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.92 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.92 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.92 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
gyrB 6115 c.876A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6133 c.894G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6203 c.964_966delAGCinsTCG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6325 c.-977C>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6329 p.Glu364Gln missense_variant 0.77 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6550 c.-752A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6556 c.-746C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.44 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7124 c.1885_1887delTCGinsAT frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>G upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7162 c.-140C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7189 c.-113C>A upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 7192 c.-110G>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7207 c.-95C>G upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7415 c.114C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7436 c.135C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7532 c.231T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7671 p.Pro124Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7766 c.465C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 7802 c.501C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7808 c.507G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7817 c.516C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8294 c.993T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8468 c.1167C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8471 c.1170T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8628 c.1327C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8681 c.1380C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8769 p.His490Tyr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8798 p.Ile499Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8799 c.1498_1500delGCGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8843 c.1542G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8846 c.1545C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8918 c.1617C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8933 c.1632G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8952 p.Gln551Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491490 c.708C>T synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491500 p.Glu240Lys missense_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491685 c.903G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 0.93 clofazimine
pretomanid
delamanid
mshA 575689 c.342G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.8 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 0.81 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575713 c.366G>A synonymous_variant 0.84 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.85 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575732 c.385_387delCTTinsTG frameshift_variant&missense_variant 0.89 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575737 c.390T>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.91 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.95 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575788 c.441C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.95 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620307 c.417C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620311 p.Leu141Val missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620332 c.442C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620335 c.445_447delCTCinsTG frameshift_variant&missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Ser missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.94 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620556 c.666C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620559 c.669A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620565 c.675G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620569 c.679_681delGGAinsCC frameshift_variant&missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620605 c.715_717delGTTinsAC frameshift_variant&missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620676 c.786C>T synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620802 c.912C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620818 c.928_930delGTTinsAC frameshift_variant&missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.96 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.96 rifampicin
nusG 734448 c.195C>T synonymous_variant 0.96 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.96 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.96 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.96 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.97 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.94 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760070 c.264T>C synonymous_variant 0.64 rifampicin
rpoB 760082 c.276C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 0.82 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.82 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.83 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.91 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.92 rifampicin
rpoB 760145 c.339C>T synonymous_variant 0.92 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.93 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.94 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>T synonymous_variant 0.94 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.92 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.92 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.92 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.97 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.95 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.92 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.95 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.94 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.93 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.93 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.93 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.94 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.98 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.98 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.98 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.98 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.97 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760784 c.978G>C synonymous_variant 1.0 rifampicin
rpoB 760787 c.981G>C synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760808 c.1002C>G synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 1.0 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.97 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.97 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.96 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.96 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.96 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.96 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.96 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.96 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.96 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.95 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.95 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761217 c.1411_1413delCCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.97 rifampicin
rpoB 761346 p.Val514Ile missense_variant 0.97 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.93 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 0.93 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.92 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.86 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761591 c.1785C>T synonymous_variant 1.0 rifampicin
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761702 c.1896C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761708 c.1902C>T synonymous_variant 1.0 rifampicin
rpoB 761718 c.1912_1913delGCinsT frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761722 p.Glu639Gly missense_variant 0.87 rifampicin Uncertain significance
rpoB 761727 p.Ser641Gly missense_variant 1.0 rifampicin
rpoB 761729 c.1925dupG frameshift_variant 1.0 rifampicin
rpoB 761736 p.Ile644Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761784 p.Thr660Ser missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.82 rifampicin
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761892 p.Ile696Val missense_variant 1.0 rifampicin
rpoB 761903 c.2097T>G synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 1.0 rifampicin
rpoB 761933 c.2127G>T synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 1.0 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>T upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.82 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762878 p.Ile1024Met missense_variant 1.0 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762926 c.3120C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.98 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.98 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.98 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.98 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 0.97 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 1.0 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763217 c.-153G>T upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 1.0 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 1.0 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.86 rifampicin
rpoC 763417 c.48C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 0.86 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 763441 c.72C>G synonymous_variant 0.86 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.86 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.97 rifampicin
rpoC 763484 c.115_117delCTTinsTG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.98 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>T synonymous_variant 0.98 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 1.0 rifampicin
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763747 c.378G>A synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763783 c.414G>T synonymous_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763816 c.447C>G synonymous_variant 1.0 rifampicin
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763837 c.468G>C synonymous_variant 1.0 rifampicin
rpoC 763840 c.471G>C synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.93 rifampicin
rpoC 763867 c.498C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763871 p.Gly168Ser missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.95 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.95 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.95 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.95 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 0.96 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763947 p.Ala193Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764080 c.711C>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 0.95 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.95 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.95 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.95 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.96 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.96 rifampicin
rpoC 764227 c.858G>T synonymous_variant 0.97 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.98 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.98 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.98 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.96 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.97 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 0.97 rifampicin
rpoC 764293 c.924G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.97 rifampicin
rpoC 764339 c.970C>T synonymous_variant 0.98 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.98 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>T synonymous_variant 0.99 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.99 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>T synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 1.0 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.99 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.99 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.98 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.94 rifampicin
rpoC 765016 c.1647C>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765022 c.1653G>C synonymous_variant 0.94 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 c.2014_2016delATGinsCC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 0.89 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.89 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.89 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.89 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.9 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.93 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.97 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 1.0 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765533 p.Tyr722His missense_variant 1.0 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.91 rifampicin
rpoC 765718 p.Asp783Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765724 c.2355C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 1.0 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765737 p.Arg790Glu missense_variant 1.0 rifampicin
rpoC 765743 p.His792Tyr missense_variant 1.0 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 1.0 rifampicin
rpoC 765779 c.2410_2412delGACinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 1.0 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.97 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.97 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.97 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.98 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.98 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.97 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.97 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.94 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.94 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 0.94 rifampicin
rpoC 766034 p.His889Asn missense_variant 0.94 rifampicin
rpoC 766042 c.2673C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Glu missense_variant 0.92 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.7 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.7 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.7 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.7 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.81 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.81 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.84 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.84 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.88 rifampicin
rpoC 766582 c.3213C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.73 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.75 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.75 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.77 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 0.77 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.77 rifampicin
rpoC 766634 p.Phe1089Ile missense_variant 0.77 rifampicin
rpoC 766638 p.Lys1090Thr missense_variant 0.77 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.79 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.85 rifampicin
rpoC 766658 c.3289_3291delCGGinsGC frameshift_variant&missense_variant 0.85 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.89 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.89 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.9 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.9 rifampicin
rpoC 766694 c.3325_3327delCAGinsGC frameshift_variant&missense_variant 0.9 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.9 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 0.9 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.91 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.91 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.91 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.92 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.97 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.97 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.97 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 1.0 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 1.0 rifampicin
rpoC 766960 c.3591C>T synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>C synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 1.0 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 1.0 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.98 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.93 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
mmpL5 775754 c.2727C>G synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 775763 c.2718T>C synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 775770 p.Ala904Gly missense_variant 0.85 clofazimine
bedaquiline
mmpL5 775772 p.Met903Ile missense_variant 0.85 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775778 c.2701_2703delACCinsGG frameshift_variant&missense_variant 0.85 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775793 c.2688C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775796 c.2683_2685delTTTinsAG frameshift_variant&stop_gained 0.88 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775817 c.2664T>C synonymous_variant 0.93 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.74 clofazimine
bedaquiline
mmpL5 775829 c.2652C>G synonymous_variant 0.82 clofazimine
bedaquiline
mmpL5 775834 p.Ala883Ser missense_variant 0.78 clofazimine
bedaquiline
mmpL5 775838 c.2643G>C synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 775847 c.2634G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775851 p.Ser877Thr missense_variant 0.81 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775862 c.2619G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775885 p.Ile866Leu missense_variant 0.63 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775889 c.2592C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775895 c.2586C>A synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.78 clofazimine
bedaquiline
mmpL5 775910 c.2571G>A synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 0.79 clofazimine
bedaquiline
mmpL5 775916 c.2565T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775922 c.2559G>A synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 775955 c.2524_2526delATCinsGG frameshift_variant&missense_variant 0.47 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775961 c.2520C>G synonymous_variant 0.57 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.51 clofazimine
bedaquiline
mmpL5 775970 c.2511G>C synonymous_variant 0.57 clofazimine
bedaquiline
mmpL5 775973 c.2506_2508delTTGinsCC frameshift_variant&missense_variant 0.37 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775994 c.2485_2487delATCinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776003 c.2476_2478delATCinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776018 c.2463G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776030 c.2451G>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776036 c.2445G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776048 c.2433G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776060 c.2421C>A synonymous_variant 0.47 clofazimine
bedaquiline
mmpL5 776075 c.2406C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776081 c.2400G>C synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 776084 c.2397C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776087 c.2394C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776107 c.2374C>T synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781572 c.13_15delCAGinsAC frameshift_variant&missense_variant 0.88 streptomycin Uncertain significance
rpsL 781595 c.36T>C synonymous_variant 0.88 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.88 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.88 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.88 streptomycin
rpsL 781622 c.63C>G synonymous_variant 0.88 streptomycin
rpsL 781631 c.72G>C synonymous_variant 0.91 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781664 c.105C>G synonymous_variant 1.0 streptomycin
rpsL 781667 c.108C>T synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781724 c.165G>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781737 p.Gln60Gly missense_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781793 c.234G>C synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>T synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781901 c.342C>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800543 c.-266C>T upstream_gene_variant 0.94 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.85 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.85 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.85 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.85 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.84 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.79 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.79 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.79 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.8 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.79 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.8 linezolid
rplC 800642 c.-167C>T upstream_gene_variant 0.81 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.79 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.8 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.83 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.85 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.85 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.82 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.81 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.81 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.85 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.85 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.83 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.83 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.83 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.87 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.86 linezolid
rplC 800892 c.84G>C synonymous_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800921 p.Arg38Leu missense_variant 1.0 linezolid
rplC 800928 c.120C>T synonymous_variant 1.0 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800964 c.156G>C synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
fbiC 1303551 c.621G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304459 p.Thr510Ser missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Asp missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304475 c.1545G>C synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304481 c.1551T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304490 c.1560C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304511 c.1581C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304515 p.Ala529Thr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304682 c.1752C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304688 c.1758C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304706 c.1776C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.83 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304736 c.1806G>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304739 c.1809C>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304766 c.1836C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.71 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304775 c.1845C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
sigE 1364784 c.372C>G synonymous_variant 0.91 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.92 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>T synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>T synonymous_variant 1.0 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 1.0 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
atpE 1461132 p.Val30Ile missense_variant 0.93 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.93 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.93 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.93 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.93 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.93 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.93 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.93 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.93 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.93 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 1.0 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 1.0 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472704 n.859C>G non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474022 n.365G>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474044 n.387C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474045 n.388C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474053 n.396G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474101 n.446_450delAGTAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474108 n.451C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474110 n.454_455insGGTGT non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_644delTCCTTTTCCTCTCCGinsCTCCTTC non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474417 n.761_767delCACGCGC non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474430 n.773delCinsTAG non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474432 n.775C>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474434 n.777_778insTG non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAAT non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475382 n.1725A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475395 n.1738T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid Uncertain significance
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673709 c.-493C>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
fabG1 1673716 p.Ala93Gln missense_variant 1.0 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
fabG1 1673760 p.Lys107Asn missense_variant 1.0 ethionamide
isoniazid
inhA 1673772 c.-430C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673799 c.-403T>G upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673808 c.-394A>C upstream_gene_variant 0.97 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 0.95 ethionamide
isoniazid
fabG1 1673830 p.Lys131Arg missense_variant 0.95 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 0.95 ethionamide
isoniazid
fabG1 1673844 p.Met135Ile missense_variant 0.95 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673865 c.-337C>G upstream_gene_variant 0.97 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 0.97 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.97 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.97 ethionamide
isoniazid
inhA 1673916 c.-286A>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673949 c.-253G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1673967 c.-235G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673985 c.-217C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674003 c.-199C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674331 p.Leu44Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674334 p.Arg45Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid
inhA 1674365 c.165_166delGG frameshift_variant 1.0 ethionamide
isoniazid
inhA 1674371 c.170delAinsGCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674375 c.174C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674378 c.177G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674379 c.178C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674382 c.181_183delCTCinsTG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674387 c.186A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674399 c.198A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674418 p.Ser73Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674421 c.220T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674428 p.Gly76Asp missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674444 c.243G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674450 c.249G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674507 c.306G>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674513 c.312C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674514 p.Ile105Val missense_variant 0.97 ethionamide
isoniazid
inhA 1674531 c.330C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674534 c.333G>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.97 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.96 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.83 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.95 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674702 c.501G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 0.95 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674732 c.531C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674738 c.537C>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674762 c.561T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674795 c.594G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674819 c.618G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674828 p.Glu209Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1674834 c.633C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674838 p.Ala213Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674852 c.651G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833554 p.Thr5Ser missense_variant 1.0 pyrazinamide
rpsA 1833562 c.21C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833565 c.24G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833574 c.33A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833607 c.66T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833688 c.147C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 c.193_195delGCCinsTG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833745 c.204G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833796 c.255G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.93 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.93 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.94 pyrazinamide
rpsA 1833862 c.321G>A synonymous_variant 0.94 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.97 pyrazinamide
rpsA 1833877 c.336C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.97 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.98 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.96 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834829 c.1288_1290delGCGinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
tsnR 1853361 c.-245T>C upstream_gene_variant 0.95 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.95 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.94 linezolid
tsnR 1853384 c.-222G>T upstream_gene_variant 0.95 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.95 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.95 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.95 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.92 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.92 linezolid
katG 2155674 c.438G>C synonymous_variant 0.88 isoniazid
katG 2155677 c.435C>T synonymous_variant 0.88 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.88 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.95 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.96 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.92 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.92 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.92 isoniazid
katG 2155737 c.375C>T synonymous_variant 0.92 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.92 isoniazid
katG 2155743 c.369G>A synonymous_variant 0.91 isoniazid Not assoc w R - Interim
katG 2155747 p.Ala122Gly missense_variant 0.92 isoniazid
katG 2155752 c.360C>T synonymous_variant 0.92 isoniazid
katG 2155764 p.His116Gln missense_variant 0.92 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.91 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.95 isoniazid
katG 2155796 p.Ala106Ser missense_variant 0.94 isoniazid
katG 2155800 c.312G>C synonymous_variant 0.92 isoniazid
katG 2155805 p.Ile103Val missense_variant 0.92 isoniazid Uncertain significance
katG 2155806 c.306T>C synonymous_variant 0.92 isoniazid
kasA 2517917 c.-198G>T upstream_gene_variant 0.91 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.88 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.86 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.85 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.84 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.82 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.81 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518768 c.654C>G synonymous_variant 1.0 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 1.0 isoniazid
kasA 2518787 c.673_675delCGGinsGT frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518792 c.678C>G synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518822 c.708C>A synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>C synonymous_variant 1.0 isoniazid
kasA 2518847 p.Leu245Met missense_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518873 c.759C>T synonymous_variant 1.0 isoniazid
kasA 2518877 p.Lys255Leu missense_variant 1.0 isoniazid
folC 2747263 c.336C>A synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747266 c.333C>T synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.87 para-aminosalicylic_acid
folC 2747290 c.309A>T synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747317 c.282C>A synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747320 c.279C>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsCG frameshift_variant&missense_variant 0.94 para-aminosalicylic_acid
folC 2747350 c.249C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2747356 p.Met81Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747377 c.222C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747386 c.213C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 1.0 para-aminosalicylic_acid
Rv2477c 2783563 c.480A>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783584 c.457_459delGCCinsCG frameshift_variant&synonymous_variant 0.83 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783593 c.450T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 0.87 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783634 p.Leu137Ile missense_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783668 c.375G>T synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783671 p.Arg124His missense_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783695 c.348C>T synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2752c 3065022 c.1170G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065025 c.1167G>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065055 c.1137T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065058 c.1134C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065061 c.1131C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065082 c.1110G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065097 c.1095C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065126 p.Ser356Ala missense_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1062A>G synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065154 c.1038G>A synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067364 c.582C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067376 c.570G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067442 c.502_504delCGCinsAA frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067457 c.489C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067463 c.481_483delATCinsGT frameshift_variant&missense_variant 0.93 para-aminosalicylic_acid
thyX 3067466 c.480G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067496 c.450G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067664 c.282C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067680 p.Cys89Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067688 c.258G>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067709 c.237G>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067724 c.222G>A synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067760 c.186G>A synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.97 para-aminosalicylic_acid
thyX 3067771 p.Gly59Ser missense_variant 0.96 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067784 c.162C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067788 p.Lys53Arg missense_variant 0.96 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067808 c.138C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067839 p.Val36Thr missense_variant 0.94 para-aminosalicylic_acid
thyX 3067841 c.105G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067862 c.84C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.94 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.93 para-aminosalicylic_acid
lpqB 3624656 c.255C>T synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624673 p.Ala80Ser missense_variant 0.85 bedaquiline
rifampicin
lpqB 3624674 p.Asn79Ser missense_variant 0.85 bedaquiline
rifampicin
lpqB 3624686 p.Glu75Asp missense_variant 0.87 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624704 c.207G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624713 c.198C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624725 c.186G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624734 c.177A>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624764 c.147C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625560 c.1052_1053delAC frameshift_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625564 c.1049_1050insGG frameshift_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625570 c.-660G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625579 c.-669A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625603 c.-693G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625623 p.Thr331Ala missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625648 c.964_966delTATinsCC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625669 c.-759G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625702 c.-792C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625705 c.-795C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625711 c.903C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625735 c.879C>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625741 c.-831G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625753 p.Ala287Gln missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625801 c.-891G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626704 c.-91C>T upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 0.94 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 0.95 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 0.95 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626783 c.-170C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3626792 c.558G>T synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627023 c.-410C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.91 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3627062 c.-449G>A upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627098 c.-485A>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627104 c.-491C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627158 c.-545C>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627215 c.-602G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627224 c.-611G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 0.7 bedaquiline
rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.88 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.96 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.93 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.92 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.92 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.94 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.93 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.93 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.93 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.91 rifampicin
rpoA 3877803 c.705G>C synonymous_variant 0.93 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.98 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.98 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.98 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.94 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.92 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 0.92 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.87 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.89 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.9 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>T synonymous_variant 1.0 rifampicin
rpoA 3878187 c.321C>A synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.93 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878232 c.276G>C synonymous_variant 0.86 rifampicin
rpoA 3878283 p.Glu75Asp missense_variant 0.8 rifampicin Uncertain significance
rpoA 3878310 c.198G>C synonymous_variant 0.77 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878400 c.108T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 1.0 rifampicin
rpoA 3878409 c.99C>G synonymous_variant 1.0 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 1.0 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 1.0 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 1.0 rifampicin
rpoA 3878433 c.75G>C synonymous_variant 1.0 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 1.0 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878450 p.Gln20Lys missense_variant 1.0 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878886 c.-379G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878890 c.-383C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 1.0 rifampicin
rpoA 3878896 c.-389G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 1.0 rifampicin
rpoA 3878977 c.-470C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878989 c.-482G>T upstream_gene_variant 1.0 rifampicin
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038410 c.2295C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038434 c.2271G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 1.0 pyrazinamide
clpC1 4038474 p.Ser744Ala missense_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 1.0 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 1.0 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038584 c.2121G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 1.0 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 1.0 pyrazinamide
clpC1 4038683 c.2020_2022delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038725 c.1980C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038770 c.1935C>A synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.96 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.96 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.95 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039319 p.Ala462Gly missense_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.96 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.96 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039592 c.1113G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039616 c.1089G>T synonymous_variant 0.98 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.98 pyrazinamide
clpC1 4039640 c.1065C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039688 c.1017G>A synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039694 c.1011G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039769 c.936C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.97 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.93 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.93 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.92 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039925 c.780C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.97 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 0.95 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040372 c.333C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.94 pyrazinamide
clpC1 4040441 c.264C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.97 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.97 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.93 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.97 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040662 c.43C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044120 c.162A>G synonymous_variant 0.88 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.88 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
panD 4044147 c.135C>G synonymous_variant 0.9 pyrazinamide
panD 4044150 c.132A>C synonymous_variant 0.9 pyrazinamide
panD 4044159 c.123C>T synonymous_variant 0.9 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 0.9 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.9 pyrazinamide
panD 4044171 c.111C>T synonymous_variant 0.9 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 0.91 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.9 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.9 pyrazinamide
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138658 c.1098C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138661 c.1095T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138696 p.Pro354Thr missense_variant 0.95 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138697 c.1059C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138754 c.1002C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138775 c.981C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138784 c.972G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138802 c.954G>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embB 4247464 c.951C>G synonymous_variant 0.92 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.92 ethambutol
embB 4247488 c.975C>T synonymous_variant 0.94 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.94 ethambutol
embB 4247494 c.981G>A synonymous_variant 0.94 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.94 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.94 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 0.83 ethambutol
embB 4247524 c.1011G>C synonymous_variant 0.84 ethambutol
embB 4247548 c.1035C>T synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embB 4247554 c.1041T>C synonymous_variant 0.75 ethambutol
embB 4247555 c.1042_1044delCTGinsAC frameshift_variant&missense_variant 0.73 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.75 ethambutol
embB 4248007 c.1494C>G synonymous_variant 1.0 ethambutol
embB 4248011 p.Ser500Ala missense_variant 1.0 ethambutol
embB 4248016 c.1503G>A synonymous_variant 1.0 ethambutol
embB 4248025 c.1512A>G synonymous_variant 1.0 ethambutol
embB 4248035 p.Val508Ile missense_variant 1.0 ethambutol
embB 4248040 c.1527C>T synonymous_variant 1.0 ethambutol
embB 4248041 p.Ala510Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 1.0 ethambutol
embB 4248052 c.1539G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248063 p.Ala517Glu missense_variant 1.0 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.92 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.92 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.95 ethambutol
embB 4248106 c.1593C>G synonymous_variant 0.96 ethambutol
embB 4248127 c.1614G>C synonymous_variant 0.96 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.96 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.96 ethambutol
embB 4248143 c.1630_1632delTTGinsAC frameshift_variant&missense_variant 0.96 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.93 ethambutol
embB 4248167 c.1654_1656delACCinsGG frameshift_variant&missense_variant 0.93 ethambutol
embB 4248170 p.Ala553Ser missense_variant 0.93 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.93 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.94 ethambutol
embB 4248203 p.Pro564Ser missense_variant 0.94 ethambutol
embB 4248206 c.1693_1695delAGCinsGA frameshift_variant&missense_variant 0.94 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.97 ethambutol Uncertain significance
embB 4248242 p.Val577Ile missense_variant 0.96 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.95 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.95 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.92 ethambutol