Run ID: ERR987722
Sample name:
Date: 2024-05-22T16:26:19.912362
Number of reads: 1795916
Percentage reads mapped: 25.02
Median coverage: 24.0
Strain:
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.6.1.2 | Euro-American | RD724 | 1.0 |
lineage3.1.2.2 | East-African-Indian | RD750 | 0.21 |
La1.7.1 | M.bovis | None | 0.22 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | katG | p.Ile335Thr | Mutation from literature | |
c.949_951delATCinsCG | Assoc w R | High-level resistance | ||
p.Ser315Thr | Assoc w R | High-level resistance | ||
c.493_495delATTinsCC | Assoc w R | High-level resistance | ||
ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
p.Asn399Asp | Mutation from literature | |||
pyrazinamide | pncA | p.Arg154Gly | Assoc w R | |
streptomycin | rrs | n.517C>T | Assoc w R | |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | tlyA | c.451_453delGTAinsAC | Assoc w R | |
c.481_483delGCTinsTG | Assoc w R | |||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.166_168delTCCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
fbiC | c.532_534delGCAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.550_552delCAAinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.952_954delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiB | c.1177_1179delCTGinsGA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 490948 | c.166_168delTCCinsGG | frameshift_variant&missense_variant | 0.74 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 0.74 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
fbiC | 1303462 | c.532_534delGCAinsTG | frameshift_variant&stop_gained | 0.38 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303480 | c.550_552delCAAinsGG | frameshift_variant&missense_variant | 0.56 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303882 | c.952_954delGTTinsAC | frameshift_variant&missense_variant | 0.32 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 0.43 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472362 | n.517C>T | non_coding_transcript_exon_variant | 0.27 | streptomycin | Assoc w R | |
tlyA | 1918390 | c.451_453delGTAinsAC | frameshift_variant&missense_variant | 0.38 | capreomycin | Assoc w R | |
tlyA | 1918420 | c.481_483delGCTinsTG | frameshift_variant&missense_variant | 0.48 | capreomycin | Assoc w R | |
katG | 2155107 | p.Ile335Thr | missense_variant | 0.54 | isoniazid | Mutation from literature | |
katG | 2155161 | c.949_951delATCinsCG | frameshift_variant&missense_variant | 0.46 | isoniazid | Assoc w R | High-level resistance |
katG | 2155168 | p.Ser315Thr | missense_variant | 0.54 | isoniazid | Assoc w R | High-level resistance |
katG | 2155617 | c.493_495delATTinsCC | frameshift_variant&missense_variant | 0.61 | isoniazid | Assoc w R | High-level resistance |
pncA | 2288782 | p.Arg154Gly | missense_variant | 1.0 | pyrazinamide | Assoc w R | |
fbiB | 3642711 | c.1177_1179delCTGinsGA | frameshift_variant&missense_variant | 0.56 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
embB | 4247580 | p.Ala356Val | missense_variant | 0.79 | ethambutol | Uncertain significance | Mutation from literature |
embB | 4247708 | p.Asn399Asp | missense_variant | 0.58 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 692 | c.694delA | frameshift_variant | 0.43 | isoniazid | Uncertain significance |
dnaA | 705 | c.705A>G | synonymous_variant | 0.62 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.66 | isoniazid | |
dnaA | 714 | c.714C>G | synonymous_variant | 0.7 | isoniazid | Not assoc w R - Interim |
dnaA | 717 | c.717C>T | synonymous_variant | 0.67 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.69 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>A | synonymous_variant | 0.64 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.65 | isoniazid | |
dnaA | 771 | c.771A>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.47 | isoniazid | Not assoc w R - Interim |
dnaA | 876 | c.876C>G | synonymous_variant | 0.6 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.59 | isoniazid | |
dnaA | 891 | c.891C>T | synonymous_variant | 0.56 | isoniazid | Not assoc w R - Interim |
dnaA | 897 | c.897A>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 903 | c.903C>G | synonymous_variant | 0.47 | isoniazid | Not assoc w R - Interim |
dnaA | 909 | c.909A>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 912 | c.912T>G | synonymous_variant | 0.53 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.62 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.67 | isoniazid | Not assoc w R - Interim |
dnaA | 984 | c.984T>C | synonymous_variant | 0.46 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>C | synonymous_variant | 0.45 | isoniazid | |
dnaA | 996 | c.996A>G | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.58 | isoniazid | Not assoc w R - Interim |
dnaA | 1020 | c.1020C>G | synonymous_variant | 0.66 | isoniazid | |
dnaA | 1023 | c.1023C>T | synonymous_variant | 0.67 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.69 | isoniazid | |
dnaA | 1029 | c.1029C>T | synonymous_variant | 0.75 | isoniazid | |
dnaA | 1050 | c.1050G>C | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.87 | isoniazid | |
dnaA | 1074 | c.1074C>G | synonymous_variant | 0.83 | isoniazid | |
dnaA | 1078 | c.1078_1080delCTCinsTG | frameshift_variant&missense_variant | 0.81 | isoniazid | Uncertain significance |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.75 | isoniazid | Not assoc w R - Interim |
dnaA | 1095 | c.1095C>T | synonymous_variant | 0.73 | isoniazid | Not assoc w R - Interim |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1119 | c.1119G>A | synonymous_variant | 0.55 | isoniazid | |
dnaA | 1125 | c.1125G>A | synonymous_variant | 0.46 | isoniazid | Not assoc w R - Interim |
dnaA | 1180 | c.1180C>T | synonymous_variant | 0.3 | isoniazid | Not assoc w R - Interim |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.53 | isoniazid | |
dnaA | 1200 | c.1200C>G | synonymous_variant | 0.54 | isoniazid | |
dnaA | 1203 | c.1203T>C | synonymous_variant | 0.57 | isoniazid | |
dnaA | 1215 | c.1215C>T | synonymous_variant | 0.62 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.67 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.75 | isoniazid | |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.79 | isoniazid | |
dnaA | 1263 | c.1263C>G | synonymous_variant | 0.74 | isoniazid | |
dnaA | 1266 | c.1266A>G | synonymous_variant | 0.72 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.73 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.69 | isoniazid | |
dnaA | 1293 | c.1293T>G | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.59 | isoniazid | Not assoc w R - Interim |
dnaA | 1302 | c.1302C>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.57 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.57 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1434 | c.1434C>A | synonymous_variant | 0.7 | isoniazid | |
dnaA | 1437 | c.1437G>A | synonymous_variant | 0.69 | isoniazid | |
dnaA | 1441 | c.1441C>T | synonymous_variant | 0.71 | isoniazid | |
dnaA | 1446 | c.1446C>G | synonymous_variant | 0.73 | isoniazid | Not assoc w R - Interim |
dnaA | 1461 | c.1461C>A | synonymous_variant | 0.7 | isoniazid | |
dnaA | 1467 | c.1467G>A | synonymous_variant | 0.7 | isoniazid | Not assoc w R - Interim |
dnaA | 1473 | c.1473T>C | synonymous_variant | 0.66 | isoniazid | Not assoc w R - Interim |
dnaA | 1497 | c.1497T>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1500 | c.1500C>G | synonymous_variant | 0.46 | isoniazid | |
dnaA | 1503 | c.1503C>T | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1506 | c.1506T>A | synonymous_variant | 0.44 | isoniazid | |
gyrB | 5329 | c.90C>T | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5338 | c.99C>T | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5341 | c.102T>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5344 | c.105C>G | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5359 | c.120C>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 5362 | c.123T>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5363 | c.124_126delTTAinsCG | frameshift_variant&missense_variant | 0.52 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 5371 | c.132T>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5396 | p.Ala53Ser | missense_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5803 | c.564A>G | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5806 | c.567C>G | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5809 | c.570C>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5812 | c.573C>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5819 | c.580C>T | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5848 | c.609G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6091 | c.852G>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6106 | c.867C>A | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6122 | p.Ala295Ser | missense_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>T | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6172 | c.933C>T | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6265 | c.1026C>T | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.79 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>A | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>G | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6316 | c.-986G>C | upstream_gene_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6326 | p.Ser363Ala | missense_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6343 | c.-959G>A | upstream_gene_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6652 | c.-650C>T | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6674 | c.1435_1437delCTTinsTG | frameshift_variant&missense_variant | 0.5 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.79 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6733 | c.-569G>A | upstream_gene_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 0.84 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6902 | c.1663_1665delCTCinsTG | frameshift_variant&missense_variant | 0.32 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 6911 | p.Asn558His | missense_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6955 | c.-347G>A | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7093 | c.1854T>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>G | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7136 | c.-166T>C | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7150 | c.-152G>C | upstream_gene_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7153 | c.-149G>T | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7156 | c.1917C>T | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7174 | c.-128C>T | upstream_gene_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7177 | c.-125G>A | upstream_gene_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7201 | c.-101G>A | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7213 | c.-89G>C | upstream_gene_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7334 | c.33G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7335 | p.Leu12Val | missense_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7349 | c.48A>G | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | c.61_63delGAGinsCA | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.77 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.79 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7412 | c.111C>G | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7422 | c.121C>T | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7433 | c.132G>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7469 | c.168C>G | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.81 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.77 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7490 | c.189C>G | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7502 | c.201C>T | synonymous_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7526 | c.225G>T | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.79 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7626 | c.325C>T | synonymous_variant | 0.79 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7643 | c.342C>T | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7679 | c.378G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7706 | c.405C>G | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7725 | c.424C>T | synonymous_variant | 0.82 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7769 | c.468C>T | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>C | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7797 | c.496_498delCTAinsTG | frameshift_variant&stop_gained | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7820 | c.519G>C | synonymous_variant | 0.84 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7832 | c.531G>T | synonymous_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>G | synonymous_variant | 0.81 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>C | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7868 | c.567C>T | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7883 | c.582G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7884 | c.583_585delCGTinsGC | frameshift_variant&missense_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7898 | p.Asp199Glu | missense_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7901 | c.600G>T | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7904 | c.603G>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820_822delTTGinsCC | frameshift_variant&missense_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8126 | c.825G>C | synonymous_variant | 0.6 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>C | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8192 | c.891C>G | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8201 | c.900C>G | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.82 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.84 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.74 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8360 | c.1059G>A | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8372 | c.1071G>T | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>G | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>T | synonymous_variant | 0.73 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8535 | p.Glu412Gln | missense_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>T | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8555 | c.1254G>C | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>G | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8585 | c.1284C>T | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>T | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8627 | c.1326C>A | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8655 | p.Ile452Val | missense_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8694 | c.1393C>T | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8765 | p.Asp488Glu | missense_variant | 0.36 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.37 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8779 | p.Asp493Ala | missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8789 | c.1488C>T | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8792 | c.1491G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8798 | c.1497C>T | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8813 | p.Asp504Glu | missense_variant | 0.31 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.31 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8924 | c.1623C>T | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8930 | c.1629C>G | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8936 | c.1635G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8983 | p.Cys561Ser | missense_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.67 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9003 | c.1702C>T | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>A | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9038 | c.1737C>G | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.59 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9062 | c.1761C>A | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9074 | c.1773G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9167 | c.1866C>T | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9183 | p.Arg628Lys | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9197 | c.1896G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9236 | c.1935G>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9248 | c.1947G>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.56 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9266 | c.1965C>T | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9315 | c.2014C>T | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9326 | c.2025G>A | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9338 | c.2037G>A | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9341 | c.2040C>G | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9368 | c.2067G>A | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13729 | c.-171G>C | upstream_gene_variant | 0.52 | isoniazid | |
Rv0010c | 13762 | c.-204G>C | upstream_gene_variant | 0.52 | isoniazid | |
Rv0010c | 13771 | c.-213T>C | upstream_gene_variant | 0.5 | isoniazid | |
Rv0010c | 13792 | c.-234G>C | upstream_gene_variant | 0.5 | isoniazid | |
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.38 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 0.47 | isoniazid | |
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490929 | c.147C>G | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490971 | c.189A>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490983 | c.201G>A | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490988 | p.Leu69Gln | missense_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490995 | c.213C>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490998 | c.216T>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491016 | c.234C>G | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491109 | c.327G>A | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491110 | p.Ala110Ser | missense_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491115 | c.333G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.59 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491136 | c.354C>T | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Glu | missense_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491166 | c.384G>T | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491168 | p.Phe129Tyr | missense_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491178 | c.396G>C | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491310 | c.528C>G | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491320 | p.Ala180Gln | missense_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491325 | c.543G>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491340 | c.558C>A | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 574595 | c.-753A>G | upstream_gene_variant | 0.58 | ethionamide | |
isoniazid | ||||||
mshA | 574607 | c.-741G>A | upstream_gene_variant | 0.76 | ethionamide | |
isoniazid | ||||||
mshA | 574616 | c.-732G>C | upstream_gene_variant | 0.74 | ethionamide | |
isoniazid | ||||||
mshA | 574640 | c.-708G>A | upstream_gene_variant | 0.76 | ethionamide | |
isoniazid | ||||||
mshA | 574646 | c.-702G>A | upstream_gene_variant | 0.74 | ethionamide | |
isoniazid | ||||||
mshA | 574650 | c.-698A>C | upstream_gene_variant | 0.73 | ethionamide | |
isoniazid | ||||||
mshA | 574667 | c.-681G>A | upstream_gene_variant | 0.75 | ethionamide | |
isoniazid | ||||||
mshA | 574673 | c.-675A>G | upstream_gene_variant | 0.75 | ethionamide | |
isoniazid | ||||||
mshA | 574676 | c.-672G>C | upstream_gene_variant | 0.74 | ethionamide | |
isoniazid | ||||||
mshA | 574683 | c.-665T>C | upstream_gene_variant | 0.74 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 574688 | c.-660G>C | upstream_gene_variant | 0.62 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 574694 | c.-654C>G | upstream_gene_variant | 0.61 | ethionamide | |
isoniazid | ||||||
mshA | 574712 | c.-636A>G | upstream_gene_variant | 0.47 | ethionamide | |
isoniazid | ||||||
mshA | 574718 | c.-630A>G | upstream_gene_variant | 0.48 | ethionamide | |
isoniazid | ||||||
mshA | 574721 | c.-627C>A | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
mshA | 574724 | c.-624T>C | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
mshA | 574727 | c.-621G>C | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
mshA | 574731 | c.-617A>G | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
mshA | 574739 | c.-609T>C | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
mshA | 575000 | c.-348C>G | upstream_gene_variant | 0.58 | ethionamide | |
isoniazid | ||||||
mshA | 575009 | c.-339T>C | upstream_gene_variant | 0.65 | ethionamide | |
isoniazid | ||||||
mshA | 575011 | c.-337G>A | upstream_gene_variant | 0.67 | ethionamide | |
isoniazid | ||||||
mshA | 575022 | c.-326C>T | upstream_gene_variant | 0.73 | ethionamide | |
isoniazid | ||||||
mshA | 575034 | c.-314_-312delTTAinsCG | upstream_gene_variant | 0.75 | ethionamide | |
isoniazid | ||||||
mshA | 575042 | c.-306T>C | upstream_gene_variant | 0.77 | ethionamide | |
isoniazid | ||||||
mshA | 575045 | c.-303C>G | upstream_gene_variant | 0.76 | ethionamide | |
isoniazid | ||||||
mshA | 575051 | c.-297A>G | upstream_gene_variant | 0.75 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 575052 | c.-296G>C | upstream_gene_variant | 0.74 | ethionamide | |
isoniazid | ||||||
mshA | 575072 | c.-276G>C | upstream_gene_variant | 0.68 | ethionamide | |
isoniazid | ||||||
mshA | 575075 | c.-273T>C | upstream_gene_variant | 0.66 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575081 | c.-267A>G | upstream_gene_variant | 0.66 | ethionamide | |
isoniazid | ||||||
mshA | 575087 | c.-261C>G | upstream_gene_variant | 0.65 | ethionamide | |
isoniazid | ||||||
mshA | 575109 | c.-239G>T | upstream_gene_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575114 | c.-234G>A | upstream_gene_variant | 0.29 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575117 | c.-231T>C | upstream_gene_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575118 | c.-230A>G | upstream_gene_variant | 0.28 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575123 | c.-225A>G | upstream_gene_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575124 | c.-224_-222delGGGinsCT | upstream_gene_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575144 | c.-204T>G | upstream_gene_variant | 0.53 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.51 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.57 | ethionamide | |
isoniazid | ||||||
mshA | 575719 | c.372C>T | synonymous_variant | 0.51 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.66 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.69 | ethionamide | |
isoniazid | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.58 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.56 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | p.Glu144Asp | missense_variant | 0.56 | ethionamide | |
isoniazid | ||||||
mshA | 575780 | c.433_435delCCGinsGC | frameshift_variant&missense_variant | 0.56 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.61 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
mshA | 575842 | c.495G>C | synonymous_variant | 0.69 | ethionamide | |
isoniazid | ||||||
mshA | 575845 | c.498C>G | synonymous_variant | 0.71 | ethionamide | |
isoniazid | ||||||
mshA | 575848 | c.501C>T | synonymous_variant | 0.73 | ethionamide | |
isoniazid | ||||||
mshA | 575851 | c.504C>G | synonymous_variant | 0.72 | ethionamide | |
isoniazid | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.73 | ethionamide | |
isoniazid | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.61 | ethionamide | |
isoniazid | ||||||
mshA | 575887 | c.540G>T | synonymous_variant | 0.57 | ethionamide | |
isoniazid | ||||||
mshA | 575890 | c.543C>G | synonymous_variant | 0.55 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.55 | ethionamide | |
isoniazid | ||||||
mshA | 575899 | c.552G>A | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
mshA | 576625 | c.1278C>G | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
mshA | 576634 | c.1287G>C | synonymous_variant | 0.35 | ethionamide | |
isoniazid | ||||||
mshA | 576659 | c.1312T>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 576667 | c.1320T>C | synonymous_variant | 0.34 | ethionamide | |
isoniazid | ||||||
mshA | 576670 | c.1323T>C | synonymous_variant | 0.35 | ethionamide | |
isoniazid | ||||||
mshA | 576676 | c.1329T>G | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
ccsA | 619588 | c.-303C>G | upstream_gene_variant | 0.28 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619594 | c.-297G>A | upstream_gene_variant | 0.34 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619624 | c.-267C>T | upstream_gene_variant | 0.56 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257_-255delTCCinsGTG | upstream_gene_variant | 0.55 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.53 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619669 | c.-222G>C | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>C | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619676 | c.-215C>T | upstream_gene_variant | 0.34 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619684 | c.-207G>A | upstream_gene_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619912 | p.Val8Ile | missense_variant | 0.53 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619923 | c.33C>G | synonymous_variant | 0.62 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619935 | c.45C>T | synonymous_variant | 0.59 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619953 | c.63C>G | synonymous_variant | 0.59 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619984 | c.94C>T | synonymous_variant | 0.46 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620197 | p.Gln103Met | missense_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620238 | c.348G>C | synonymous_variant | 0.55 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620245 | c.355T>C | synonymous_variant | 0.57 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620249 | p.Ser120Cys | missense_variant | 0.57 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620253 | c.363G>C | synonymous_variant | 0.54 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 0.53 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620271 | c.381C>G | synonymous_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.44 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620325 | c.435G>C | synonymous_variant | 0.41 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620343 | c.453G>C | synonymous_variant | 0.44 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>T | synonymous_variant | 0.41 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.44 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>C | synonymous_variant | 0.27 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.27 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620394 | c.504G>A | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620400 | c.510C>T | synonymous_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620613 | c.723C>G | synonymous_variant | 0.6 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 0.63 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620631 | c.741T>G | synonymous_variant | 0.68 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 0.68 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620652 | c.762C>G | synonymous_variant | 0.69 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 0.73 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620685 | c.795G>A | synonymous_variant | 0.69 | capreomycin | Not assoc w R - Interim |
amikacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620698 | p.Val270Ile | missense_variant | 0.66 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620712 | c.822G>C | synonymous_variant | 0.63 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>A | synonymous_variant | 0.6 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.63 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>C | synonymous_variant | 0.67 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.71 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620781 | c.891C>G | synonymous_variant | 0.68 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620783 | p.Ala298Val | missense_variant | 0.69 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620787 | c.897C>A | synonymous_variant | 0.7 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620796 | c.906C>G | synonymous_variant | 0.7 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656265 | c.1206G>C | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656268 | p.Met401Ile | missense_variant | 0.43 | ethionamide | |
Rv0565c | 656292 | c.1179G>C | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 656304 | c.1167T>C | synonymous_variant | 0.47 | ethionamide | |
Rv0565c | 656307 | c.1164G>C | synonymous_variant | 0.47 | ethionamide | |
Rv0565c | 656310 | c.1161T>C | synonymous_variant | 0.47 | ethionamide | |
Rv0565c | 656322 | c.1149C>T | synonymous_variant | 0.46 | ethionamide | |
Rv0565c | 656325 | c.1146C>G | synonymous_variant | 0.46 | ethionamide | |
Rv0565c | 656334 | c.1137A>G | synonymous_variant | 0.46 | ethionamide | |
Rv0565c | 657210 | c.261C>T | synonymous_variant | 0.47 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657213 | c.258C>T | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 657219 | p.Ala84Val | missense_variant | 0.53 | ethionamide | |
Rv0565c | 657233 | p.Ile80Val | missense_variant | 0.67 | ethionamide | |
Rv0565c | 657240 | c.229_231delGAAinsAG | frameshift_variant&synonymous_variant | 0.63 | ethionamide | Uncertain significance |
Rv0565c | 657252 | c.219G>C | synonymous_variant | 0.74 | ethionamide | |
Rv0565c | 657255 | c.216G>A | synonymous_variant | 0.76 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.78 | ethionamide | |
Rv0565c | 657279 | c.192C>T | synonymous_variant | 0.82 | ethionamide | |
Rv0565c | 657294 | c.177C>A | synonymous_variant | 0.79 | ethionamide | |
Rv0565c | 657306 | c.165C>T | synonymous_variant | 0.71 | ethionamide | |
Rv0565c | 657312 | c.159C>T | synonymous_variant | 0.68 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.6 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 657644 | c.-174G>C | upstream_gene_variant | 0.48 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.59 | ethionamide | |
Rv0565c | 657659 | c.-189G>A | upstream_gene_variant | 0.64 | ethionamide | |
Rv0565c | 657668 | c.-198C>T | upstream_gene_variant | 0.72 | ethionamide | |
Rv0565c | 657678 | c.-208A>C | upstream_gene_variant | 0.68 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.7 | ethionamide | |
Rv0565c | 657695 | c.-225C>G | upstream_gene_variant | 0.67 | ethionamide | |
Rv0565c | 657704 | c.-234G>A | upstream_gene_variant | 0.61 | ethionamide | |
Rv0565c | 657725 | c.-255G>A | upstream_gene_variant | 0.55 | ethionamide | |
hadA | 731708 | c.-222G>A | upstream_gene_variant | 0.34 | isoniazid | |
hadA | 731711 | c.-219T>C | upstream_gene_variant | 0.42 | isoniazid | |
hadA | 731726 | c.-204C>G | upstream_gene_variant | 0.56 | isoniazid | |
hadA | 731729 | c.-201C>T | upstream_gene_variant | 0.57 | isoniazid | |
hadA | 731753 | c.-177A>C | upstream_gene_variant | 0.68 | isoniazid | |
hadA | 731756 | c.-174C>T | upstream_gene_variant | 0.69 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.73 | isoniazid | |
hadA | 731786 | c.-144C>G | upstream_gene_variant | 0.8 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.73 | isoniazid | |
hadA | 731807 | c.-123C>T | upstream_gene_variant | 0.67 | isoniazid | |
hadA | 731819 | c.-111G>C | upstream_gene_variant | 0.62 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.54 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 0.48 | isoniazid | |
hadA | 732280 | c.351C>G | synonymous_variant | 0.22 | isoniazid | |
hadA | 732305 | c.376_378delATCinsGG | frameshift_variant&missense_variant | 0.34 | isoniazid | Uncertain significance |
hadA | 732308 | p.Val127Ile | missense_variant | 0.33 | isoniazid | |
hadA | 732314 | p.Asn129Asp | missense_variant | 0.38 | isoniazid | |
hadA | 732319 | c.390G>A | synonymous_variant | 0.47 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.47 | isoniazid | |
hadA | 732329 | p.Leu134Ile | missense_variant | 0.6 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.7 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.9 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.88 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.87 | isoniazid | |
nusG | 734053 | c.-201A>T | upstream_gene_variant | 0.42 | rifampicin | |
nusG | 734078 | c.-176C>G | upstream_gene_variant | 0.65 | rifampicin | Uncertain significance |
nusG | 734093 | c.-161A>G | upstream_gene_variant | 0.64 | rifampicin | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.62 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.61 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.62 | rifampicin | Uncertain significance |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.58 | rifampicin | |
nusG | 734224 | c.-30G>C | upstream_gene_variant | 0.38 | rifampicin | |
nusG | 734225 | c.-29C>T | upstream_gene_variant | 0.38 | rifampicin | |
nusG | 734229 | c.-25A>T | upstream_gene_variant | 0.4 | rifampicin | |
nusG | 734230 | c.-24G>A | upstream_gene_variant | 0.4 | rifampicin | |
nusG | 734233 | c.-21T>C | upstream_gene_variant | 0.4 | rifampicin | |
nusG | 734236 | c.-18C>T | upstream_gene_variant | 0.45 | rifampicin | |
nusG | 734403 | c.150C>T | synonymous_variant | 0.65 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.65 | rifampicin | |
nusG | 734421 | c.168A>C | synonymous_variant | 0.71 | rifampicin | |
nusG | 734424 | c.171G>C | synonymous_variant | 0.69 | rifampicin | |
nusG | 734439 | c.186C>G | synonymous_variant | 0.69 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.71 | rifampicin | |
nusG | 734454 | c.201A>G | synonymous_variant | 0.69 | rifampicin | |
nusG | 734472 | c.219T>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
nusG | 734475 | c.222T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
nusG | 734478 | c.225C>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 0.72 | rifampicin | |
nusG | 734520 | c.267C>A | synonymous_variant | 0.76 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.73 | rifampicin | |
nusG | 734571 | c.318C>G | synonymous_variant | 0.66 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.59 | rifampicin | |
nusG | 734595 | c.342C>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
nusG | 734596 | c.343T>C | synonymous_variant | 0.56 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.5 | rifampicin | |
nusG | 734814 | c.561G>C | synonymous_variant | 0.67 | rifampicin | |
nusG | 734820 | c.567A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
nusG | 734826 | c.573A>G | synonymous_variant | 0.74 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
nusG | 734841 | c.588G>T | synonymous_variant | 0.77 | rifampicin | |
nusG | 734853 | c.600A>G | synonymous_variant | 0.79 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 0.79 | rifampicin | |
nusG | 734870 | p.Ser206Asn | missense_variant | 0.83 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 0.82 | rifampicin | |
nusG | 734910 | c.657C>G | synonymous_variant | 0.79 | rifampicin | |
nusG | 734913 | c.660C>G | synonymous_variant | 0.79 | rifampicin | |
nusG | 734931 | c.678A>T | synonymous_variant | 0.67 | rifampicin | |
nusG | 734940 | c.687G>A | synonymous_variant | 0.61 | rifampicin | |
nusG | 734943 | c.690G>C | synonymous_variant | 0.54 | rifampicin | |
nusG | 734950 | p.Gly233Thr | missense_variant | 0.46 | rifampicin | |
rpoB | 760043 | c.237C>T | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760046 | c.240G>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760056 | c.250_252delCTCinsTG | frameshift_variant&missense_variant | 0.46 | rifampicin | |
rpoB | 760070 | c.264T>G | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.72 | rifampicin | |
rpoB | 760118 | c.312T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.82 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.76 | rifampicin | |
rpoB | 760145 | c.339C>G | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760181 | c.375T>A | synonymous_variant | 0.82 | rifampicin | |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 760244 | c.438G>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 760274 | c.468G>A | synonymous_variant | 0.81 | rifampicin | |
rpoB | 760295 | c.489C>T | synonymous_variant | 0.79 | rifampicin | |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.75 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.67 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.57 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760358 | c.552C>G | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.57 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.55 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.55 | rifampicin | |
rpoB | 760412 | c.606C>T | synonymous_variant | 0.58 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 760457 | c.651C>T | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 760472 | c.666C>T | synonymous_variant | 0.67 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 760478 | c.672C>T | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>T | synonymous_variant | 0.65 | rifampicin | |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 760493 | c.687C>G | synonymous_variant | 0.74 | rifampicin | |
rpoB | 760520 | c.714C>G | synonymous_variant | 0.61 | rifampicin | |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.61 | rifampicin | Uncertain significance |
rpoB | 760526 | c.720G>A | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.53 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.68 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.78 | rifampicin | |
rpoB | 760601 | c.795C>T | synonymous_variant | 0.83 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 760622 | c.816C>T | synonymous_variant | 0.83 | rifampicin | |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 760649 | c.843G>C | synonymous_variant | 0.84 | rifampicin | |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 760667 | c.861G>A | synonymous_variant | 0.84 | rifampicin | |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.85 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 760748 | c.942C>G | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.61 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.61 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.69 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.85 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.84 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.85 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | c.1039_1041delACCinsCG | frameshift_variant&missense_variant | 0.87 | rifampicin | |
rpoB | 760856 | c.1050C>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.81 | rifampicin | |
rpoB | 760916 | c.1110C>G | synonymous_variant | 0.71 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.76 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.74 | rifampicin | |
rpoB | 760937 | c.1131G>A | synonymous_variant | 0.75 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 760973 | c.1167G>C | synonymous_variant | 0.8 | rifampicin | |
rpoB | 760982 | c.1176G>T | synonymous_variant | 0.78 | rifampicin | |
rpoB | 760985 | c.1179G>T | synonymous_variant | 0.78 | rifampicin | |
rpoB | 760991 | c.1185G>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 761006 | c.1200C>T | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.83 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 761096 | c.1290G>C | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.71 | rifampicin | |
rpoB | 761192 | c.1386C>G | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 761240 | c.1434C>T | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>C | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761282 | c.1476C>G | synonymous_variant | 0.83 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 761345 | c.1539G>T | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.79 | rifampicin | |
rpoB | 761374 | p.Val523Glu | missense_variant | 0.78 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.67 | rifampicin | |
rpoB | 761432 | c.1626C>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.58 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.5 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.51 | rifampicin | |
rpoB | 761465 | c.1659G>A | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 761471 | c.1665C>T | synonymous_variant | 0.51 | rifampicin | |
rpoB | 761477 | c.1671C>T | synonymous_variant | 0.55 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.66 | rifampicin | |
rpoB | 761504 | c.1698C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.83 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761558 | c.1752C>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>A | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.8 | rifampicin | |
rpoB | 761666 | c.1860G>C | synonymous_variant | 0.76 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.75 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 0.53 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.58 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.68 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.62 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.62 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.6 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.66 | rifampicin | |
rpoB | 761828 | c.2022C>T | synonymous_variant | 0.68 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 761837 | c.2031C>T | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.58 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.59 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.61 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.75 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.78 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.72 | rifampicin | |
rpoB | 761913 | c.2107_2109delGACinsCA | frameshift_variant&missense_variant | 0.71 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.72 | rifampicin | |
rpoB | 761921 | c.2115C>T | synonymous_variant | 0.75 | rifampicin | |
rpoB | 761930 | c.2124G>C | synonymous_variant | 0.8 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.82 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.82 | rifampicin | |
rpoB | 762047 | c.2241G>A | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.84 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.79 | rifampicin | |
rpoB | 762134 | c.2328C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.77 | rifampicin | |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>T | synonymous_variant | 0.73 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.77 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.76 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.77 | rifampicin | |
rpoB | 762278 | c.2472C>T | synonymous_variant | 0.79 | rifampicin | |
rpoB | 762281 | c.2475G>A | synonymous_variant | 0.78 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.82 | rifampicin | |
rpoB | 762341 | c.2535G>C | synonymous_variant | 0.82 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.83 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.81 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.74 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.74 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 762431 | c.2625C>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 762491 | c.2685T>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.76 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.79 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.78 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.78 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.7 | rifampicin | |
rpoC | 762563 | c.-807G>A | upstream_gene_variant | 0.61 | rifampicin | |
rpoC | 762581 | c.-789T>C | upstream_gene_variant | 0.43 | rifampicin | |
rpoC | 762587 | c.-783G>A | upstream_gene_variant | 0.27 | rifampicin | |
rpoC | 762776 | c.-594C>G | upstream_gene_variant | 0.43 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.64 | rifampicin | Uncertain significance |
rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.64 | rifampicin | |
rpoB | 762795 | p.Asp997Asn | missense_variant | 0.66 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.79 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 762833 | c.3027C>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 762860 | c.-510G>T | upstream_gene_variant | 0.8 | rifampicin | |
rpoC | 762902 | c.-468C>T | upstream_gene_variant | 0.82 | rifampicin | |
rpoC | 762917 | c.-453C>T | upstream_gene_variant | 0.81 | rifampicin | |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>G | upstream_gene_variant | 0.82 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 763082 | c.3276C>T | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.73 | rifampicin | |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.73 | rifampicin | |
rpoC | 763205 | c.-165G>T | upstream_gene_variant | 0.7 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 0.69 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.72 | rifampicin | |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 763241 | c.-129G>A | upstream_gene_variant | 0.73 | rifampicin | |
rpoC | 763250 | c.-120C>T | upstream_gene_variant | 0.66 | rifampicin | |
rpoC | 763253 | c.-117G>T | upstream_gene_variant | 0.65 | rifampicin | |
rpoC | 763262 | c.-108C>A | upstream_gene_variant | 0.53 | rifampicin | |
rpoC | 763265 | c.-105G>A | upstream_gene_variant | 0.42 | rifampicin | |
rpoB | 763283 | c.3477T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763284 | c.-86C>T | upstream_gene_variant | 0.38 | rifampicin | |
rpoC | 763289 | c.-81C>G | upstream_gene_variant | 0.38 | rifampicin | |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.38 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.42 | rifampicin | Uncertain significance |
rpoC | 763402 | c.33C>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 763409 | c.40_42delCTTinsTG | frameshift_variant&missense_variant | 0.76 | rifampicin | |
rpoC | 763414 | c.45T>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.75 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.78 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>T | synonymous_variant | 0.82 | rifampicin | |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.82 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 763703 | c.334_336delTCGinsAGC | synonymous_variant | 0.79 | rifampicin | |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.82 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 763726 | c.357C>T | synonymous_variant | 0.87 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.85 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 763765 | c.396T>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoC | 763771 | c.402C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.85 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.83 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 763836 | p.Ala156Val | missense_variant | 0.82 | rifampicin | |
rpoC | 763851 | p.Ala161Gly | missense_variant | 0.76 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.81 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.79 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.75 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.79 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.76 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.75 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.81 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.79 | rifampicin | |
rpoC | 763951 | c.582G>A | synonymous_variant | 0.82 | rifampicin | |
rpoC | 763963 | c.594C>G | synonymous_variant | 0.83 | rifampicin | |
rpoC | 763967 | p.Gly200Ser | missense_variant | 0.84 | rifampicin | |
rpoC | 763972 | c.603C>T | synonymous_variant | 0.84 | rifampicin | |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.77 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.84 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.82 | rifampicin | |
rpoC | 764044 | c.675T>G | synonymous_variant | 0.81 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.86 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 764159 | c.790C>T | synonymous_variant | 0.83 | rifampicin | |
rpoC | 764167 | c.798G>A | synonymous_variant | 0.83 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.79 | rifampicin | |
rpoC | 764215 | c.846A>C | synonymous_variant | 0.84 | rifampicin | |
rpoC | 764218 | c.849C>T | synonymous_variant | 0.87 | rifampicin | |
rpoC | 764242 | c.873C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 764245 | c.876C>A | synonymous_variant | 0.83 | rifampicin | |
rpoC | 764246 | c.877_879delCTCinsTG | frameshift_variant&missense_variant | 0.83 | rifampicin | |
rpoC | 764263 | c.894G>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 764293 | c.924G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 764317 | c.948C>G | synonymous_variant | 0.82 | rifampicin | |
rpoC | 764320 | c.951C>G | synonymous_variant | 0.82 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 764377 | c.1008C>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.75 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.73 | rifampicin | |
rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 0.77 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.75 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.76 | rifampicin | |
rpoC | 764605 | c.1236G>A | synonymous_variant | 0.81 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 764686 | c.1317C>T | synonymous_variant | 0.89 | rifampicin | |
rpoC | 764746 | c.1377G>C | synonymous_variant | 0.8 | rifampicin | |
rpoC | 764749 | c.1380G>C | synonymous_variant | 0.8 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 764782 | c.1413C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.78 | rifampicin | |
rpoC | 764803 | c.1434C>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.77 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 764887 | c.1518G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519_1521delTTGinsCC | frameshift_variant&missense_variant | 0.63 | rifampicin | |
rpoC | 764896 | c.1527C>T | synonymous_variant | 0.64 | rifampicin | |
rpoC | 764902 | c.1533C>T | synonymous_variant | 0.66 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.73 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>G | synonymous_variant | 0.75 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 765013 | c.1644C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 765065 | c.1696C>T | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765079 | c.1710T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>A | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 765121 | c.1752G>T | synonymous_variant | 0.55 | rifampicin | |
rpoC | 765208 | c.1839T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765223 | c.1854G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765233 | c.1864_1866delGCCinsTG | frameshift_variant&missense_variant | 0.4 | rifampicin | |
rpoC | 765247 | c.1878C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765248 | c.1879T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765251 | c.1882_1884delAGCinsTCG | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765278 | c.1909C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 765283 | c.1914C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765292 | c.1923G>T | synonymous_variant | 0.52 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.52 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 765328 | p.His653Gln | missense_variant | 0.75 | rifampicin | Uncertain significance |
rpoC | 765330 | p.Ser654Asn | missense_variant | 0.75 | rifampicin | Uncertain significance |
rpoC | 765334 | c.1965C>T | synonymous_variant | 0.74 | rifampicin | |
rpoC | 765343 | c.1974G>A | synonymous_variant | 0.74 | rifampicin | |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 765367 | c.1998C>G | synonymous_variant | 0.68 | rifampicin | |
rpoC | 765370 | c.2001G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.67 | rifampicin | Uncertain significance |
rpoC | 765391 | c.2022C>T | synonymous_variant | 0.66 | rifampicin | |
rpoC | 765406 | c.2037G>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 0.72 | rifampicin | |
rpoC | 765466 | c.2097C>T | synonymous_variant | 0.72 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 765493 | c.2124G>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 765517 | c.2148C>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.75 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.78 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 0.75 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.76 | rifampicin | |
rpoC | 765622 | p.Glu751Asp | missense_variant | 0.76 | rifampicin | |
rpoC | 765625 | c.2256C>T | synonymous_variant | 0.77 | rifampicin | |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 765670 | c.2301C>T | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765728 | p.Gln787Lys | missense_variant | 0.79 | rifampicin | |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 765752 | p.Asp795Ser | missense_variant | 0.62 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.59 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.65 | rifampicin | |
rpoC | 765790 | c.2421C>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.66 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 765904 | c.2535C>T | synonymous_variant | 0.76 | rifampicin | |
rpoC | 765934 | c.2565C>T | synonymous_variant | 0.76 | rifampicin | |
rpoC | 765952 | c.2583G>T | synonymous_variant | 0.78 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 766012 | c.2643C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766061 | p.Val898Ile | missense_variant | 0.78 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.61 | rifampicin | |
rpoC | 766093 | c.2724C>A | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766095 | p.Thr909Ser | missense_variant | 0.59 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766123 | c.2754C>A | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 766147 | c.2778C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766148 | p.Thr927Ala | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoC | 766168 | c.2799C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766270 | c.2901G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.48 | rifampicin | |
rpoC | 766280 | c.2911_2913delAGCinsGT | frameshift_variant&missense_variant | 0.5 | rifampicin | |
rpoC | 766288 | c.2919C>G | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766309 | c.2940G>A | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766315 | c.2946C>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 766321 | c.2952C>G | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 766369 | c.3000C>G | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.76 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.78 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.78 | rifampicin | |
rpoC | 766402 | c.3033C>G | synonymous_variant | 0.79 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 0.8 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 0.78 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.75 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.75 | rifampicin | |
rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.76 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.73 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766585 | c.3216T>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.74 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766660 | c.3291G>A | synonymous_variant | 0.84 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.83 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 766700 | c.3331C>T | synonymous_variant | 0.8 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.83 | rifampicin | |
rpoC | 766733 | c.3364C>T | synonymous_variant | 0.82 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.82 | rifampicin | |
rpoC | 766741 | c.3372G>C | synonymous_variant | 0.82 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.81 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.8 | rifampicin | |
rpoC | 766798 | c.3429C>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.75 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.76 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 766883 | c.3514_3516delTCGinsGC | frameshift_variant&missense_variant | 0.78 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.73 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.75 | rifampicin | |
rpoC | 766903 | c.3534C>T | synonymous_variant | 0.78 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 766996 | c.3627C>G | synonymous_variant | 0.69 | rifampicin | |
rpoC | 767002 | c.3633G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.75 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.82 | rifampicin | |
rpoC | 767158 | c.3789T>A | synonymous_variant | 0.7 | rifampicin | |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.67 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>G | synonymous_variant | 0.6 | rifampicin | |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.58 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.59 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.3 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.37 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.56 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.59 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775997 | c.2484T>C | synonymous_variant | 0.53 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776000 | c.2479_2481delCTGinsAC | frameshift_variant&missense_variant | 0.45 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.58 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776030 | c.2451G>T | synonymous_variant | 0.63 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776036 | c.2445G>T | synonymous_variant | 0.59 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776039 | c.2442C>G | synonymous_variant | 0.52 | clofazimine | |
bedaquiline | ||||||
rpsL | 781134 | c.-426T>C | upstream_gene_variant | 0.44 | streptomycin | |
rpsL | 781138 | c.-422C>G | upstream_gene_variant | 0.43 | streptomycin | |
rpsL | 781143 | c.-417T>C | upstream_gene_variant | 0.43 | streptomycin | |
rpsL | 781152 | c.-408G>A | upstream_gene_variant | 0.59 | streptomycin | |
rpsL | 781164 | c.-396T>C | upstream_gene_variant | 0.64 | streptomycin | |
rpsL | 781170 | c.-390G>C | upstream_gene_variant | 0.64 | streptomycin | |
rpsL | 781173 | c.-387A>G | upstream_gene_variant | 0.64 | streptomycin | |
rpsL | 781174 | c.-386C>T | upstream_gene_variant | 0.64 | streptomycin | |
rpsL | 781185 | c.-375T>C | upstream_gene_variant | 0.67 | streptomycin | |
rpsL | 781188 | c.-372G>C | upstream_gene_variant | 0.68 | streptomycin | |
rpsL | 781189 | c.-371T>C | upstream_gene_variant | 0.66 | streptomycin | |
rpsL | 781206 | c.-354C>T | upstream_gene_variant | 0.54 | streptomycin | |
rpsL | 781209 | c.-351C>G | upstream_gene_variant | 0.52 | streptomycin | |
rpsL | 781224 | c.-336T>C | upstream_gene_variant | 0.35 | streptomycin | |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781571 | c.12C>T | synonymous_variant | 0.63 | streptomycin | |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.65 | streptomycin | |
rpsL | 781598 | c.39G>C | synonymous_variant | 0.66 | streptomycin | |
rpsL | 781605 | p.Ile16Val | missense_variant | 0.67 | streptomycin | Uncertain significance |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.68 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.76 | streptomycin | Not assoc w R - Interim |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.75 | streptomycin | |
rpsL | 781658 | c.99A>G | synonymous_variant | 0.74 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781718 | c.159C>G | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781721 | c.162C>T | synonymous_variant | 0.8 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.8 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781766 | c.207C>T | synonymous_variant | 0.84 | streptomycin | Not assoc w R - Interim |
rpsL | 781772 | c.213C>G | synonymous_variant | 0.81 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.8 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.78 | streptomycin | |
rpsL | 781832 | c.273T>G | synonymous_variant | 0.77 | streptomycin | |
rpsL | 781835 | c.276T>C | synonymous_variant | 0.76 | streptomycin | Not assoc w R - Interim |
rpsL | 781859 | c.300T>G | synonymous_variant | 0.78 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.77 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.74 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.72 | streptomycin | |
rpsL | 781883 | c.324G>A | synonymous_variant | 0.74 | streptomycin | |
rpsL | 781886 | c.327C>T | synonymous_variant | 0.73 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.75 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.74 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.78 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.74 | streptomycin | Uncertain significance |
rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 0.75 | streptomycin | |
rplC | 800201 | c.-608A>G | upstream_gene_variant | 0.47 | linezolid | |
rplC | 800209 | c.-600C>T | upstream_gene_variant | 0.49 | linezolid | |
rplC | 800212 | c.-597C>A | upstream_gene_variant | 0.5 | linezolid | |
rplC | 800216 | c.-593A>G | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800222 | c.-587G>A | upstream_gene_variant | 0.45 | linezolid | |
rplC | 800225 | c.-584T>C | upstream_gene_variant | 0.43 | linezolid | |
rplC | 800238 | c.-571A>G | upstream_gene_variant | 0.47 | linezolid | |
rplC | 800252 | c.-557C>A | upstream_gene_variant | 0.44 | linezolid | |
rplC | 800272 | c.-537C>T | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800278 | c.-531A>G | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800329 | c.-480C>T | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800341 | c.-468G>C | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800348 | c.-461_-460insA | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800358 | c.-450delT | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800386 | c.-423T>C | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.68 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.76 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.8 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.8 | linezolid | |
rplC | 800579 | c.-230C>T | upstream_gene_variant | 0.78 | linezolid | |
rplC | 800582 | c.-227C>T | upstream_gene_variant | 0.77 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.76 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.75 | linezolid | |
rplC | 800621 | c.-188G>A | upstream_gene_variant | 0.75 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.74 | linezolid | |
rplC | 800648 | c.-161A>G | upstream_gene_variant | 0.72 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.73 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800703 | c.-106_-104delTTGinsCC | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800714 | c.-95C>T | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.67 | linezolid | |
rplC | 800744 | c.-65G>C | upstream_gene_variant | 0.57 | linezolid | |
rplC | 800745 | c.-64_-62delCTCinsTG | upstream_gene_variant | 0.54 | linezolid | |
rplC | 800759 | c.-50C>T | upstream_gene_variant | 0.51 | linezolid | |
rplC | 800762 | c.-47T>G | upstream_gene_variant | 0.49 | linezolid | |
rplC | 800798 | c.-11_-8delTGGAinsC | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800806 | c.-3G>T | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800807 | c.-2_-1insT | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.41 | linezolid | |
rplC | 800815 | c.7C>A | synonymous_variant | 0.43 | linezolid | |
rplC | 800820 | c.12G>A | synonymous_variant | 0.52 | linezolid | |
rplC | 800829 | c.21C>G | synonymous_variant | 0.69 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.75 | linezolid | |
rplC | 800856 | c.48A>G | synonymous_variant | 0.75 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.73 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.74 | linezolid | |
rplC | 800872 | c.64_66delAGAinsCG | frameshift_variant&synonymous_variant | 0.77 | linezolid | |
rplC | 800877 | c.69A>C | synonymous_variant | 0.77 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.77 | linezolid | |
rplC | 800901 | c.93C>G | synonymous_variant | 0.75 | linezolid | |
rplC | 800910 | c.102C>T | synonymous_variant | 0.71 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.66 | linezolid | |
rplC | 800919 | c.111C>G | synonymous_variant | 0.65 | linezolid | |
rplC | 800931 | c.123G>C | synonymous_variant | 0.65 | linezolid | |
rplC | 800934 | c.126C>G | synonymous_variant | 0.65 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.62 | linezolid | |
rplC | 800946 | c.138T>A | synonymous_variant | 0.66 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 0.63 | linezolid | |
rplC | 800962 | p.Leu52Val | missense_variant | 0.5 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 0.31 | linezolid | |
rplC | 801180 | c.372C>G | synonymous_variant | 0.43 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.56 | linezolid | |
rplC | 801201 | c.393C>T | synonymous_variant | 0.57 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.55 | linezolid | |
rplC | 801210 | c.402T>C | synonymous_variant | 0.57 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 0.68 | linezolid | |
rplC | 801228 | c.420T>C | synonymous_variant | 0.68 | linezolid | |
rplC | 801231 | c.423C>T | synonymous_variant | 0.7 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.69 | linezolid | |
rplC | 801285 | c.477G>A | synonymous_variant | 0.62 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.63 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.61 | linezolid | |
rplC | 801324 | c.516T>C | synonymous_variant | 0.48 | linezolid | |
rplC | 801330 | c.522G>T | synonymous_variant | 0.5 | linezolid | |
rplC | 801333 | c.525G>C | synonymous_variant | 0.52 | linezolid | |
rplC | 801339 | c.531T>G | synonymous_variant | 0.41 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.43 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.44 | linezolid | |
rplC | 801349 | p.Leu181Val | missense_variant | 0.44 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.46 | linezolid | |
rplC | 801385 | c.577C>T | synonymous_variant | 0.59 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.62 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.62 | linezolid | |
rplC | 801408 | c.600C>A | synonymous_variant | 0.61 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.62 | linezolid | |
rplC | 801426 | c.618C>T | synonymous_variant | 0.61 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.61 | linezolid | |
rplC | 801437 | p.Ser210Thr | missense_variant | 0.61 | linezolid | |
rplC | 801461 | c.653G>A | splice_region_variant&stop_retained_variant | 0.55 | linezolid | |
fbiC | 1303470 | c.540T>G | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303488 | c.558G>C | synonymous_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303506 | c.576C>T | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.78 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303538 | p.Arg203Leu | missense_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303578 | c.648G>A | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303596 | c.666G>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.59 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303620 | c.690C>T | synonymous_variant | 0.59 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303629 | c.699C>T | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303661 | p.Val244Ala | missense_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303719 | c.789C>T | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303869 | c.939T>C | synonymous_variant | 0.41 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303881 | c.951G>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303890 | c.960G>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303893 | c.963G>A | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303913 | p.Gly328Asp | missense_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303923 | c.993C>T | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303986 | c.1056C>T | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304001 | c.1071C>T | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304013 | c.1083G>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304019 | c.1089C>T | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304055 | c.1125C>T | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304178 | c.1248G>A | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304184 | c.1254G>T | synonymous_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304190 | c.1260G>C | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304196 | c.1266C>A | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304205 | c.1275C>A | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304220 | c.1290G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304222 | p.Val431Ala | missense_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304226 | c.1296C>G | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304227 | p.Met433Leu | missense_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304478 | c.1548G>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304481 | c.1551T>G | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304496 | c.1566T>A | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304499 | c.1569T>G | synonymous_variant | 0.56 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304502 | c.1572G>C | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304532 | c.1602G>C | synonymous_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304533 | c.1603T>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304541 | c.1611C>G | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304546 | p.Val539Ala | missense_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304610 | c.1680C>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>A | synonymous_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304797 | p.Ala623Asn | missense_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304823 | c.1893C>T | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.51 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>G | synonymous_variant | 0.57 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304868 | c.1938G>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304871 | c.1941G>T | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304872 | c.1942_1943delAGinsTC | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304883 | c.1953G>A | synonymous_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304915 | p.Asp662Gly | missense_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304934 | c.2004C>G | synonymous_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.77 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304955 | c.2025G>A | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304991 | c.2061G>C | synonymous_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.76 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.76 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>A | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305033 | c.2103T>C | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305039 | c.2109G>A | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305354 | c.2424C>T | synonymous_variant | 0.63 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1305357 | c.2427C>G | synonymous_variant | 0.66 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1305361 | c.2431C>T | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305393 | c.2463T>C | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305397 | p.Glu823Gln | missense_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305414 | c.2484G>A | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305417 | c.2487C>G | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305423 | c.2493T>G | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305426 | c.2496G>A | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305427 | c.2497C>T | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305435 | c.2505G>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364839 | c.427T>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364847 | c.435G>C | synonymous_variant | 0.33 | pyrazinamide | |
sigE | 1364856 | c.444C>G | synonymous_variant | 0.46 | pyrazinamide | |
sigE | 1364868 | c.456T>C | synonymous_variant | 0.54 | pyrazinamide | |
sigE | 1364871 | c.459C>G | synonymous_variant | 0.6 | pyrazinamide | |
sigE | 1364883 | c.471G>A | synonymous_variant | 0.69 | pyrazinamide | |
sigE | 1364889 | c.477A>G | synonymous_variant | 0.7 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364892 | c.480C>G | synonymous_variant | 0.69 | pyrazinamide | |
sigE | 1364913 | c.501C>G | synonymous_variant | 0.65 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.58 | pyrazinamide | |
sigE | 1364925 | c.513C>G | synonymous_variant | 0.52 | pyrazinamide | |
sigE | 1364928 | c.516C>T | synonymous_variant | 0.49 | pyrazinamide | |
sigE | 1364952 | c.540A>C | synonymous_variant | 0.3 | pyrazinamide | |
embR | 1416301 | c.1047C>A | synonymous_variant | 0.39 | ethambutol | |
embR | 1416310 | c.1038G>C | synonymous_variant | 0.48 | ethambutol | |
embR | 1416313 | c.1035A>G | synonymous_variant | 0.47 | ethambutol | |
embR | 1416316 | c.1032C>G | synonymous_variant | 0.49 | ethambutol | |
embR | 1416330 | p.Val340Ile | missense_variant | 0.54 | ethambutol | |
embR | 1416332 | p.Tyr339Phe | missense_variant | 0.54 | ethambutol | |
embR | 1416335 | p.Asn338Ser | missense_variant | 0.56 | ethambutol | |
embR | 1416343 | c.1005G>C | synonymous_variant | 0.62 | ethambutol | |
embR | 1416364 | c.984C>T | synonymous_variant | 0.63 | ethambutol | |
embR | 1416386 | p.Asp321Ala | missense_variant | 0.43 | ethambutol | |
embR | 1416388 | c.960A>G | synonymous_variant | 0.38 | ethambutol | |
embR | 1416393 | p.Val319Ile | missense_variant | 0.38 | ethambutol | Uncertain significance |
atpE | 1460807 | c.-238C>T | upstream_gene_variant | 0.74 | bedaquiline | |
atpE | 1460816 | c.-229T>C | upstream_gene_variant | 0.73 | bedaquiline | |
atpE | 1460828 | c.-217C>T | upstream_gene_variant | 0.69 | bedaquiline | |
atpE | 1460831 | c.-214T>C | upstream_gene_variant | 0.66 | bedaquiline | |
atpE | 1460840 | c.-205A>G | upstream_gene_variant | 0.69 | bedaquiline | |
atpE | 1460855 | c.-190T>C | upstream_gene_variant | 0.71 | bedaquiline | |
atpE | 1460858 | c.-187C>G | upstream_gene_variant | 0.74 | bedaquiline | |
atpE | 1460882 | c.-163T>C | upstream_gene_variant | 0.7 | bedaquiline | |
atpE | 1460894 | c.-151A>G | upstream_gene_variant | 0.54 | bedaquiline | |
atpE | 1460895 | c.-150_-148delGCAinsTC | upstream_gene_variant | 0.52 | bedaquiline | |
atpE | 1460900 | c.-145T>C | upstream_gene_variant | 0.54 | bedaquiline | |
atpE | 1460904 | c.-141C>T | upstream_gene_variant | 0.56 | bedaquiline | |
atpE | 1460918 | c.-127A>G | upstream_gene_variant | 0.57 | bedaquiline | |
atpE | 1460927 | c.-118C>G | upstream_gene_variant | 0.4 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.74 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.74 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.73 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.73 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.59 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.68 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>T | non_coding_transcript_exon_variant | 0.68 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.68 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.69 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472040 | n.195T>C | non_coding_transcript_exon_variant | 0.68 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.72 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.78 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.74 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 0.6 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472686 | n.841G>A | non_coding_transcript_exon_variant | 0.68 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 0.55 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472848 | n.1003T>G | non_coding_transcript_exon_variant | 0.55 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 0.55 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472859 | n.1014G>C | non_coding_transcript_exon_variant | 0.52 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 0.54 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.77 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.77 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.72 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.74 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.69 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.65 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473288 | n.1443C>T | non_coding_transcript_exon_variant | 0.77 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.76 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.76 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473417 | n.-241C>T | upstream_gene_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1473420 | n.-238A>G | upstream_gene_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1473421 | n.-237G>A | upstream_gene_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1473437 | n.-221T>C | upstream_gene_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1473659 | n.2T>C | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473676 | n.19G>A | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473797 | n.140G>T | non_coding_transcript_exon_variant | 0.87 | capreomycin | |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | |
linezolid | ||||||
rrl | 1473831 | n.174G>A | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473887 | n.230T>A | non_coding_transcript_exon_variant | 0.81 | capreomycin | |
linezolid | ||||||
rrl | 1473888 | n.231T>A | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1473918 | n.261C>T | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1473981 | n.324delGinsAT | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1473994 | n.337C>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | ||||||
rrl | 1474011 | n.354G>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474018 | n.361G>A | non_coding_transcript_exon_variant | 0.81 | capreomycin | |
linezolid | ||||||
rrl | 1474030 | n.373G>A | non_coding_transcript_exon_variant | 0.76 | capreomycin | |
linezolid | ||||||
rrl | 1474061 | n.404T>C | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1474089 | n.432C>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474100 | n.443C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1474110 | n.453A>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 0.63 | capreomycin | |
linezolid | ||||||
rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 0.76 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1474447 | n.790G>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.82 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 0.76 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.82 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.82 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475013 | n.1356G>A | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1475018 | n.1361G>A | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
linezolid | ||||||
rrl | 1475027 | n.1370G>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | ||||||
rrl | 1475028 | n.1371G>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | |
linezolid | ||||||
rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475404 | n.1747A>G | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475453 | n.1796T>A | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475487 | n.1830C>T | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475605 | n.1948A>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475617 | n.1960C>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1475625 | n.1968G>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1475637 | n.1980T>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475760 | n.2103C>T | non_coding_transcript_exon_variant | 0.76 | capreomycin | |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.77 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475999 | n.2342G>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1476047 | n.2390G>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476077 | n.2420T>C | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 0.87 | capreomycin | |
linezolid | ||||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1476725 | n.3068C>T | non_coding_transcript_exon_variant | 0.76 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.76 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476755 | n.3098G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476770 | n.3113T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476771 | n.3114G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
inhA | 1673475 | c.-727A>C | upstream_gene_variant | 0.47 | ethionamide | |
isoniazid | ||||||
inhA | 1673499 | c.-703T>C | upstream_gene_variant | 0.69 | ethionamide | |
isoniazid | Uncertain significance | |||||
inhA | 1673505 | c.-697A>T | upstream_gene_variant | 0.7 | ethionamide | |
isoniazid | ||||||
inhA | 1673517 | c.-685G>C | upstream_gene_variant | 0.69 | ethionamide | |
isoniazid | ||||||
inhA | 1673524 | c.-678C>T | upstream_gene_variant | 0.73 | ethionamide | |
isoniazid | ||||||
inhA | 1673535 | c.-667A>G | upstream_gene_variant | 0.76 | ethionamide | |
isoniazid | ||||||
inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.75 | ethionamide | |
isoniazid | ||||||
inhA | 1673856 | c.-346T>G | upstream_gene_variant | 0.48 | ethionamide | |
isoniazid | ||||||
inhA | 1673865 | c.-337C>G | upstream_gene_variant | 0.57 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673870 | p.Ser144Met | missense_variant | 0.57 | ethionamide | |
isoniazid | ||||||
inhA | 1673877 | c.-325C>T | upstream_gene_variant | 0.67 | ethionamide | |
isoniazid | ||||||
inhA | 1673901 | c.-301A>C | upstream_gene_variant | 0.71 | ethionamide | |
isoniazid | ||||||
inhA | 1673904 | c.-298C>G | upstream_gene_variant | 0.71 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673905 | p.Ser156Ala | missense_variant | 0.71 | ethionamide | |
isoniazid | ||||||
inhA | 1673916 | c.-286A>C | upstream_gene_variant | 0.69 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673917 | p.Val160Leu | missense_variant | 0.69 | ethionamide | |
isoniazid | ||||||
inhA | 1673922 | c.-280T>C | upstream_gene_variant | 0.69 | ethionamide | |
isoniazid | ||||||
inhA | 1673925 | c.-277C>G | upstream_gene_variant | 0.69 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673941 | p.Ala168Ser | missense_variant | 0.6 | ethionamide | |
isoniazid | ||||||
inhA | 1673946 | c.-256C>G | upstream_gene_variant | 0.56 | ethionamide | |
isoniazid | ||||||
inhA | 1674452 | p.Ala84Glu | missense_variant | 0.24 | ethionamide | |
isoniazid | ||||||
inhA | 1674463 | c.262_264delCTCinsAT | frameshift_variant&missense_variant | 0.38 | ethionamide | |
isoniazid | ||||||
inhA | 1674471 | c.270G>C | synonymous_variant | 0.34 | ethionamide | |
isoniazid | ||||||
inhA | 1674480 | c.279T>C | synonymous_variant | 0.4 | ethionamide | |
isoniazid | ||||||
inhA | 1674489 | c.288G>T | synonymous_variant | 0.4 | ethionamide | |
isoniazid | ||||||
inhA | 1674507 | c.306G>A | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
inhA | 1674534 | c.333G>C | synonymous_variant | 0.62 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674537 | c.336C>A | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
inhA | 1674540 | c.339C>T | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.61 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.63 | ethionamide | |
isoniazid | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.68 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.7 | ethionamide | |
isoniazid | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.71 | ethionamide | |
isoniazid | ||||||
inhA | 1674588 | c.387G>A | synonymous_variant | 0.68 | ethionamide | |
isoniazid | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.68 | ethionamide | |
isoniazid | ||||||
inhA | 1674601 | p.Leu134Val | missense_variant | 0.64 | ethionamide | |
isoniazid | ||||||
inhA | 1674618 | c.417C>T | synonymous_variant | 0.6 | ethionamide | |
isoniazid | ||||||
inhA | 1674619 | p.Pro140Ser | missense_variant | 0.6 | ethionamide | |
isoniazid | ||||||
inhA | 1674624 | c.423A>T | synonymous_variant | 0.62 | ethionamide | |
isoniazid | ||||||
inhA | 1674627 | c.426T>C | synonymous_variant | 0.65 | ethionamide | |
isoniazid | ||||||
inhA | 1674655 | c.454_456delAGCinsTCG | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
inhA | 1674669 | c.468G>C | synonymous_variant | 0.65 | ethionamide | |
isoniazid | ||||||
inhA | 1674687 | c.486G>A | synonymous_variant | 0.73 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674690 | c.489C>G | synonymous_variant | 0.73 | ethionamide | |
isoniazid | ||||||
inhA | 1674696 | c.495G>A | synonymous_variant | 0.72 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.76 | ethionamide | |
isoniazid | ||||||
inhA | 1674717 | c.516C>T | synonymous_variant | 0.67 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.67 | ethionamide | |
isoniazid | ||||||
inhA | 1674729 | c.528G>A | synonymous_variant | 0.66 | ethionamide | |
isoniazid | ||||||
inhA | 1674792 | c.591G>C | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.56 | ethionamide | |
isoniazid | ||||||
inhA | 1674820 | c.619_621delCTCinsTG | frameshift_variant&missense_variant | 0.6 | ethionamide | |
isoniazid | ||||||
inhA | 1674828 | c.627G>A | synonymous_variant | 0.64 | ethionamide | |
isoniazid | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.72 | ethionamide | |
isoniazid | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.8 | ethionamide | |
isoniazid | ||||||
inhA | 1674876 | c.675C>G | synonymous_variant | 0.79 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.78 | ethionamide | |
isoniazid | ||||||
inhA | 1674888 | c.687C>T | synonymous_variant | 0.8 | ethionamide | |
isoniazid | ||||||
inhA | 1674904 | c.703_705delGCGinsCC | frameshift_variant&missense_variant | 0.77 | ethionamide | |
isoniazid | ||||||
inhA | 1674909 | c.708G>C | synonymous_variant | 0.79 | ethionamide | |
isoniazid | ||||||
inhA | 1674915 | c.714C>G | synonymous_variant | 0.79 | ethionamide | |
isoniazid | ||||||
inhA | 1674939 | c.738G>A | synonymous_variant | 0.74 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674942 | c.741T>C | synonymous_variant | 0.73 | ethionamide | |
isoniazid | ||||||
rpsA | 1833262 | c.-280T>C | upstream_gene_variant | 0.49 | pyrazinamide | |
rpsA | 1833273 | c.-269G>A | upstream_gene_variant | 0.55 | pyrazinamide | |
rpsA | 1833277 | c.-265C>G | upstream_gene_variant | 0.57 | pyrazinamide | |
rpsA | 1833283 | c.-259C>G | upstream_gene_variant | 0.58 | pyrazinamide | |
rpsA | 1833288 | c.-254_-253delTGinsCC | upstream_gene_variant | 0.58 | pyrazinamide | |
rpsA | 1833304 | c.-238C>G | upstream_gene_variant | 0.62 | pyrazinamide | |
rpsA | 1833310 | c.-232T>C | upstream_gene_variant | 0.63 | pyrazinamide | |
rpsA | 1833319 | c.-223C>G | upstream_gene_variant | 0.57 | pyrazinamide | |
rpsA | 1833340 | c.-202G>C | upstream_gene_variant | 0.51 | pyrazinamide | |
rpsA | 1833343 | c.-199G>C | upstream_gene_variant | 0.46 | pyrazinamide | |
rpsA | 1833352 | c.-190C>G | upstream_gene_variant | 0.4 | pyrazinamide | |
rpsA | 1833356 | c.-186_-185delAGinsTC | upstream_gene_variant | 0.37 | pyrazinamide | |
rpsA | 1833367 | c.-175G>C | upstream_gene_variant | 0.33 | pyrazinamide | |
rpsA | 1833370 | c.-172G>C | upstream_gene_variant | 0.29 | pyrazinamide | |
rpsA | 1833517 | c.-24delC | upstream_gene_variant | 0.58 | pyrazinamide | |
rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.6 | pyrazinamide | |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.73 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.73 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.72 | pyrazinamide | |
rpsA | 1833613 | c.72C>A | synonymous_variant | 0.73 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.74 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.74 | pyrazinamide | |
rpsA | 1833703 | c.162C>T | synonymous_variant | 0.72 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.72 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.73 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1833760 | c.219C>T | synonymous_variant | 0.78 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1833808 | c.267G>C | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 0.79 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.77 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.77 | pyrazinamide | |
rpsA | 1833859 | c.318C>T | synonymous_variant | 0.79 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.79 | pyrazinamide | |
rpsA | 1833895 | c.354G>C | synonymous_variant | 0.81 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.86 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833970 | c.429G>A | synonymous_variant | 0.86 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.7 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.69 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 0.58 | pyrazinamide | Uncertain significance |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.69 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834186 | c.645C>G | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.73 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.76 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1834225 | c.684C>G | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1834231 | c.690T>G | synonymous_variant | 0.8 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.83 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834279 | c.738C>T | synonymous_variant | 0.86 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834297 | c.756C>T | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834336 | c.795C>G | synonymous_variant | 0.88 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.86 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.85 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1834396 | c.855G>T | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.9 | pyrazinamide | |
rpsA | 1834423 | c.882G>T | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.86 | pyrazinamide | |
rpsA | 1834456 | c.915T>G | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834477 | c.936C>T | synonymous_variant | 0.86 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834510 | c.969C>T | synonymous_variant | 0.85 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834519 | c.978G>C | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834603 | c.1062G>A | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834612 | c.1071G>A | synonymous_variant | 0.84 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.86 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834654 | c.1113G>A | synonymous_variant | 0.88 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1834699 | p.Glu386Asp | missense_variant | 0.84 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834813 | c.1272G>A | synonymous_variant | 0.64 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834852 | c.1311C>G | synonymous_variant | 0.72 | pyrazinamide | |
rpsA | 1834858 | c.1317G>A | synonymous_variant | 0.71 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834864 | c.1323T>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834869 | p.Arg443His | missense_variant | 0.46 | pyrazinamide | |
tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853393 | c.-213C>T | upstream_gene_variant | 0.25 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.24 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1918377 | c.438T>G | synonymous_variant | 0.4 | capreomycin | |
tlyA | 1918380 | c.441C>T | synonymous_variant | 0.44 | capreomycin | |
tlyA | 1918395 | c.456G>C | synonymous_variant | 0.36 | capreomycin | |
tlyA | 1918410 | c.471C>T | synonymous_variant | 0.4 | capreomycin | Not assoc w R - Interim |
tlyA | 1918442 | p.Val168Ala | missense_variant | 0.48 | capreomycin | |
tlyA | 1918446 | c.507A>T | synonymous_variant | 0.44 | capreomycin | |
tlyA | 1918452 | c.513T>G | synonymous_variant | 0.45 | capreomycin | |
tlyA | 1918454 | p.Ser172Trp | missense_variant | 0.42 | capreomycin | |
tlyA | 1918457 | p.Arg173Pro | missense_variant | 0.41 | capreomycin | |
tlyA | 1918460 | p.Asp174Gly | missense_variant | 0.41 | capreomycin | |
tlyA | 1918464 | c.525C>G | synonymous_variant | 0.41 | capreomycin | |
tlyA | 1918476 | c.537A>C | synonymous_variant | 0.48 | capreomycin | |
tlyA | 1918477 | p.Leu180Met | missense_variant | 0.48 | capreomycin | |
tlyA | 1918497 | c.558G>A | synonymous_variant | 0.32 | capreomycin | Not assoc w R - Interim |
bacA | 2064891 | c.-163C>G | upstream_gene_variant | 0.23 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064900 | c.-172G>A | upstream_gene_variant | 0.3 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064912 | c.-184A>G | upstream_gene_variant | 0.32 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064933 | c.-205A>C | upstream_gene_variant | 0.42 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064934 | c.-208_-206delCTCinsTG | upstream_gene_variant | 0.42 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.44 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064951 | c.-223C>G | upstream_gene_variant | 0.46 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
ndh | 2101804 | c.1239T>G | synonymous_variant | 0.4 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101813 | c.1230G>A | synonymous_variant | 0.46 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101825 | c.1218G>A | synonymous_variant | 0.52 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101837 | p.Ala402Val | missense_variant | 0.55 | ethionamide | Uncertain significance |
delamanid | ||||||
isoniazid | Uncertain significance | |||||
ndh | 2101858 | p.Ile395Met | missense_variant | 0.53 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101873 | c.1170T>C | synonymous_variant | 0.48 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101879 | c.1164C>T | synonymous_variant | 0.45 | ethionamide | Not assoc w R - Interim |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2101890 | p.Val385Leu | missense_variant | 0.34 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101894 | c.1149T>C | synonymous_variant | 0.32 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101897 | c.1146C>T | synonymous_variant | 0.25 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102632 | c.411C>T | synonymous_variant | 0.54 | ethionamide | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2102638 | c.405A>G | synonymous_variant | 0.57 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102644 | c.399A>G | synonymous_variant | 0.62 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102671 | c.372T>G | synonymous_variant | 0.63 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102674 | c.369G>A | synonymous_variant | 0.59 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102677 | c.366C>G | synonymous_variant | 0.58 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102683 | c.360T>C | synonymous_variant | 0.6 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102686 | c.357G>C | synonymous_variant | 0.6 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102700 | c.343C>T | synonymous_variant | 0.53 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102929 | c.114T>C | synonymous_variant | 0.36 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102938 | p.Arg35His | missense_variant | 0.38 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102959 | c.84C>T | synonymous_variant | 0.25 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102962 | c.81A>C | synonymous_variant | 0.23 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
katG | 2155026 | c.1086C>G | synonymous_variant | 0.5 | isoniazid | |
katG | 2155047 | c.1065C>G | synonymous_variant | 0.56 | isoniazid | |
katG | 2155054 | p.Tyr353Phe | missense_variant | 0.48 | isoniazid | |
katG | 2155056 | c.1056A>G | synonymous_variant | 0.48 | isoniazid | |
katG | 2155062 | c.1050T>C | synonymous_variant | 0.5 | isoniazid | |
katG | 2155068 | c.1044T>G | synonymous_variant | 0.58 | isoniazid | |
katG | 2155071 | c.1041T>G | synonymous_variant | 0.58 | isoniazid | |
katG | 2155080 | c.1032G>C | synonymous_variant | 0.57 | isoniazid | |
katG | 2155083 | c.1029G>C | synonymous_variant | 0.53 | isoniazid | |
katG | 2155086 | c.1026G>A | synonymous_variant | 0.55 | isoniazid | |
katG | 2155119 | c.993T>C | synonymous_variant | 0.48 | isoniazid | |
katG | 2155131 | c.981A>G | synonymous_variant | 0.52 | isoniazid | Not assoc w R - Interim |
katG | 2155134 | c.978G>C | synonymous_variant | 0.56 | isoniazid | |
katG | 2155144 | p.Asn323Pro | missense_variant | 0.54 | isoniazid | |
katG | 2155152 | c.960A>G | synonymous_variant | 0.48 | isoniazid | |
katG | 2155155 | c.957C>G | synonymous_variant | 0.46 | isoniazid | |
katG | 2155185 | c.927T>C | synonymous_variant | 0.36 | isoniazid | |
katG | 2155614 | c.498T>G | synonymous_variant | 0.61 | isoniazid | |
katG | 2155626 | c.486G>C | synonymous_variant | 0.62 | isoniazid | |
katG | 2155632 | c.480A>G | synonymous_variant | 0.59 | isoniazid | |
katG | 2155637 | p.Leu159Ile | missense_variant | 0.61 | isoniazid | |
katG | 2155641 | p.Lys157Asn | missense_variant | 0.61 | isoniazid | Uncertain significance |
katG | 2155651 | p.Lys154Arg | missense_variant | 0.64 | isoniazid | |
katG | 2155656 | c.456G>A | synonymous_variant | 0.7 | isoniazid | |
katG | 2155661 | p.Val151Ile | missense_variant | 0.67 | isoniazid | |
katG | 2155680 | c.432G>C | synonymous_variant | 0.52 | isoniazid | |
katG | 2155691 | c.421T>C | synonymous_variant | 0.56 | isoniazid | |
katG | 2155695 | c.417C>G | synonymous_variant | 0.56 | isoniazid | |
katG | 2155716 | c.396T>C | synonymous_variant | 0.5 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 0.44 | isoniazid | |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.73 | isoniazid | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.78 | isoniazid | |
kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.74 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.7 | isoniazid | |
kasA | 2517983 | c.-132T>C | upstream_gene_variant | 0.69 | isoniazid | |
kasA | 2517989 | c.-126T>G | upstream_gene_variant | 0.66 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.69 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 0.62 | isoniazid | |
kasA | 2518025 | c.-90G>C | upstream_gene_variant | 0.56 | isoniazid | |
kasA | 2518031 | c.-84G>T | upstream_gene_variant | 0.47 | isoniazid | |
kasA | 2518034 | c.-81T>C | upstream_gene_variant | 0.44 | isoniazid | |
kasA | 2518040 | c.-75G>T | upstream_gene_variant | 0.43 | isoniazid | |
kasA | 2518041 | c.-74T>C | upstream_gene_variant | 0.43 | isoniazid | |
kasA | 2518049 | c.-66G>C | upstream_gene_variant | 0.39 | isoniazid | |
kasA | 2518053 | c.-62_-60delATTinsCG | upstream_gene_variant | 0.37 | isoniazid | |
kasA | 2518132 | c.18C>T | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518138 | c.24T>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518146 | p.Phe11Tyr | missense_variant | 0.57 | isoniazid | |
kasA | 2518152 | p.Ser13Asn | missense_variant | 0.58 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 0.69 | isoniazid | |
kasA | 2518169 | p.Val19Leu | missense_variant | 0.67 | isoniazid | |
kasA | 2518172 | c.58_60delACAinsGG | frameshift_variant&missense_variant | 0.68 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 0.75 | isoniazid | |
kasA | 2518199 | p.Ile29Val | missense_variant | 0.75 | isoniazid | |
kasA | 2518219 | c.105T>C | synonymous_variant | 0.68 | isoniazid | |
kasA | 2518220 | c.106C>T | synonymous_variant | 0.68 | isoniazid | |
kasA | 2518245 | p.His44Arg | missense_variant | 0.64 | isoniazid | |
kasA | 2518248 | p.Ala45Val | missense_variant | 0.61 | isoniazid | |
kasA | 2518261 | p.Glu49Asp | missense_variant | 0.65 | isoniazid | |
kasA | 2518273 | c.159G>A | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518279 | p.Asp55Glu | missense_variant | 0.49 | isoniazid | |
kasA | 2518282 | c.168A>G | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518283 | p.Ala57Pro | missense_variant | 0.46 | isoniazid | |
kasA | 2518289 | p.Lys59Gln | missense_variant | 0.54 | isoniazid | |
kasA | 2518297 | c.183C>T | synonymous_variant | 0.62 | isoniazid | |
kasA | 2518300 | c.186T>A | synonymous_variant | 0.6 | isoniazid | |
kasA | 2518312 | p.Asp66Glu | missense_variant | 0.48 | isoniazid | |
kasA | 2518316 | p.Val68Ile | missense_variant | 0.5 | isoniazid | |
kasA | 2518321 | c.207C>T | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518323 | p.Ser70Asn | missense_variant | 0.5 | isoniazid | |
kasA | 2518336 | c.222A>G | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518339 | c.225C>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518342 | c.228C>T | synonymous_variant | 0.42 | isoniazid | |
kasA | 2518343 | p.Met77Leu | missense_variant | 0.42 | isoniazid | |
kasA | 2518351 | c.237C>G | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518363 | c.249C>T | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518492 | c.378C>T | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.48 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518534 | c.420G>C | synonymous_variant | 0.46 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.61 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.49 | isoniazid | |
kasA | 2518573 | c.459G>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518574 | p.Ile154Val | missense_variant | 0.44 | isoniazid | |
kasA | 2518582 | c.468G>C | synonymous_variant | 0.46 | isoniazid | |
kasA | 2518583 | c.469_471delCAGinsGA | frameshift_variant&missense_variant | 0.46 | isoniazid | |
kasA | 2518594 | c.480C>T | synonymous_variant | 0.55 | isoniazid | |
kasA | 2518597 | c.483C>G | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518606 | c.492G>C | synonymous_variant | 0.63 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.64 | isoniazid | |
kasA | 2518636 | c.522C>A | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518639 | c.525G>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518645 | c.531G>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518651 | c.537C>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518693 | c.579C>G | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.55 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.59 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518717 | c.603C>G | synonymous_variant | 0.63 | isoniazid | |
kasA | 2518723 | c.609G>A | synonymous_variant | 0.7 | isoniazid | |
kasA | 2518735 | c.621C>T | synonymous_variant | 0.75 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.77 | isoniazid | |
kasA | 2518768 | c.654C>G | synonymous_variant | 0.78 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.76 | isoniazid | |
kasA | 2518789 |