TB-Profiler result

Run: SRR6511621
Summary

Run ID: SRR6511621

Sample name:

Date: 2024-10-05T05:11:16.919587

Number of reads: 424788

Percentage reads mapped: 17.76

Median coverage: 3.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1.1.1 Euro-American (X-type) RD183 0.05
lineage3.1.2.2 East-African-Indian RD750 0.06
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.88
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.85 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.85 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.85 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.85 isoniazid
dnaA 769 p.Ala257Ser missense_variant 0.85 isoniazid Uncertain significance
dnaA 783 c.783C>T synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 793 p.Val265Ile missense_variant 0.8 isoniazid Uncertain significance
dnaA 799 p.Val267Ile missense_variant 0.67 isoniazid
dnaA 805 c.805_807delTTGinsCTC synonymous_variant 0.67 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.6 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.6 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.6 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.6 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.6 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.6 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.6 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.6 isoniazid Not assoc w R - Interim
dnaA 864 c.864C>T synonymous_variant 0.6 isoniazid
gyrB 6175 c.936G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6196 c.957C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.93 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGC synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6227 p.Lys330Arg missense_variant 0.81 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6241 p.Asp334Glu missense_variant 0.72 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.72 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6283 p.Asp348Glu missense_variant 0.72 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6307 c.1068T>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6322 c.1084_1085dupGT frameshift_variant 0.72 levofloxacin Uncertain significance
moxifloxacin
gyrB 6327 c.1088_1090delGCGinsC frameshift_variant&missense_variant 0.72 levofloxacin Uncertain significance
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6352 c.1113C>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6358 c.1119C>G synonymous_variant 0.63 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6550 c.-752A>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6551 c.1312T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 6601 c.-701A>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6607 c.-695T>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6685 c.-617C>A upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.83 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.86 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6838 c.-464C>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6872 c.-430_-428delTTGinsCTC upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6881 c.-421_-419delTTGinsCTT upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 6896 p.Arg553Lys missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6931 c.-371A>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7451 c.150C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7454 c.153G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7637 c.336C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7673 c.372G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCGT synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7709 c.408G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7808 c.507G>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 7901 c.600G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7906 p.Phe202Tyr missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8129 c.828T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8191 p.Ala297Gly missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8240 c.939C>A synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8279 c.978G>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.81 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.83 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8357 c.1056G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364Leu missense_variant 0.62 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8456 c.1155C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8477 c.1176C>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8549 c.1248C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>A synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9176 c.1875G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9213 p.Thr638Val missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.75 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9323 c.2022C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9329 c.2028C>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCGC synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9407 c.2106C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491490 c.708C>T synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 491493 c.711C>T synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fgd1 491499 c.717G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 0.79 pretomanid
delamanid
clofazimine
fgd1 491536 c.754C>T synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>T synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fgd1 491548 p.Ala256Pro missense_variant 0.94 pretomanid
delamanid
clofazimine
fgd1 491562 c.780C>T synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491571 c.789C>T synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fgd1 491595 c.813C>T synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491604 c.822G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.74 pretomanid
delamanid
clofazimine
mshA 575689 c.342G>C synonymous_variant 0.79 isoniazid
ethionamide
mshA 575692 c.345G>A synonymous_variant 0.88 isoniazid
ethionamide
mshA 575704 c.357T>C synonymous_variant 0.86 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.86 isoniazid
ethionamide
mshA 575725 c.378C>G synonymous_variant 0.95 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 0.95 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 0.94 isoniazid Uncertain significance
ethionamide
mshA 575749 c.402C>A synonymous_variant 0.94 isoniazid
ethionamide
mshA 575761 c.414C>G synonymous_variant 0.94 isoniazid
ethionamide
mshA 575764 c.417C>G synonymous_variant 0.93 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 0.93 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 0.93 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.93 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.94 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 0.94 isoniazid
ethionamide
mshA 575800 c.453G>C synonymous_variant 0.94 isoniazid
ethionamide
mshA 575803 c.456C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
ethionamide
mshA 575821 c.474G>T synonymous_variant 0.95 isoniazid
ethionamide
mshA 575837 c.490C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620242 p.Cys118Ser missense_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620247 p.Leu119Phe missense_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620253 c.363G>C synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620264 p.Gly125Ala missense_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620271 c.381C>G synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620275 c.385C>T synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620296 p.Pro136Ala missense_variant 0.8 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620311 p.Leu141Val missense_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620316 c.426G>C synonymous_variant 0.92 kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
ccsA 620340 c.450C>G synonymous_variant 0.78 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.78 kanamycin
capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Ser missense_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620397 c.507C>G synonymous_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620652 c.762C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620715 c.825C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620736 c.846G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620764 p.Ala292Ser missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620781 c.891C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620793 c.903G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620796 c.906C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620802 c.912C>G synonymous_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 620808 c.918T>C synonymous_variant 0.82 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv0565c 657601 c.-131A>T upstream_gene_variant 0.62 ethionamide
Rv0565c 657636 c.-167_-166delAGinsTC upstream_gene_variant 0.69 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.69 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.69 ethionamide
Rv0565c 657662 c.-192C>T upstream_gene_variant 0.69 ethionamide
Rv0565c 657668 c.-200_-198delACCinsGCG upstream_gene_variant 0.69 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.69 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.69 ethionamide
Rv0565c 657683 c.-213C>G upstream_gene_variant 0.71 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.83 ethionamide
Rv0565c 657703 c.-233C>A upstream_gene_variant 0.87 ethionamide
Rv0565c 657722 c.-254_-252delAACinsCAG upstream_gene_variant 0.88 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.87 ethionamide
nusG 734424 c.171G>C synonymous_variant 0.73 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.86 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.75 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.75 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.75 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.75 rifampicin
nusG 734521 p.Thr90Ala missense_variant 0.59 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.53 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.46 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760059 p.Tyr85Glu missense_variant 1.0 rifampicin
rpoB 760067 c.261G>C synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>C synonymous_variant 1.0 rifampicin
rpoB 760082 c.276C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 1.0 rifampicin
rpoB 760139 c.333A>T synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760325 c.519G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>T synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>T synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 1.0 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 1.0 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 1.0 rifampicin
rpoB 760571 c.765G>C synonymous_variant 1.0 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760595 c.789C>T synonymous_variant 1.0 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.95 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.93 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.86 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.86 rifampicin
rpoB 760755 p.His317Asn missense_variant 0.86 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.86 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.86 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.86 rifampicin
rpoB 760784 c.978G>T synonymous_variant 0.87 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.87 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.88 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.89 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.89 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.89 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.89 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.89 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.89 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.89 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.91 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.91 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.9 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.93 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.93 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.93 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761087 c.1281C>G synonymous_variant 1.0 rifampicin
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761111 c.1305C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 1.0 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761288 c.1482G>T synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 1.0 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761366 c.1560C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Asp missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761436 p.Ala544Pro missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>C synonymous_variant 1.0 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 1.0 rifampicin
rpoB 761712 p.Val636Ile missense_variant 1.0 rifampicin
rpoB 761727 p.Ser641Gly missense_variant 1.0 rifampicin
rpoB 761736 p.Ile644Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761785 p.Thr660Ser missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761795 c.1989C>G synonymous_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 1.0 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 1.0 rifampicin
rpoB 761868 p.Asp688Gln missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761892 p.Ile696Val missense_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>A synonymous_variant 1.0 rifampicin
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.97 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762509 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762920 c.3114C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.9 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.94 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.94 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.75 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.71 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.93 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.93 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.93 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 0.93 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.93 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.94 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>T synonymous_variant 0.96 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.98 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.96 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.96 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.96 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.96 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.96 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.94 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.92 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.91 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.91 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.91 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.92 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.92 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.93 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.93 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.93 rifampicin
rpoC 763882 c.513G>A synonymous_variant 0.93 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.93 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.93 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.89 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.89 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.89 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.91 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.91 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.91 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.9 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.89 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.84 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.82 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.79 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.79 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.83 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.83 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.83 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.83 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.8 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.78 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.78 rifampicin
rpoC 764089 c.720C>G synonymous_variant 0.74 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.82 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.96 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.96 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.96 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 0.88 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.88 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.88 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.88 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.88 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.88 rifampicin
rpoC 764227 c.858G>T synonymous_variant 0.88 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>A synonymous_variant 0.89 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.9 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.9 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.88 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.89 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.89 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.9 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764353 c.984G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.96 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.96 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.96 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.96 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.96 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.97 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.94 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 1.0 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765016 c.1647C>T synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765400 c.2031G>C synonymous_variant 1.0 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 1.0 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.88 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.88 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.88 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.89 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.89 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.89 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.94 rifampicin Uncertain significance
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765577 c.2208G>T synonymous_variant 1.0 rifampicin
rpoC 765743 p.His792Tyr missense_variant 1.0 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 1.0 rifampicin
rpoC 765779 p.Asp804Lys missense_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 1.0 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 1.0 rifampicin
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 1.0 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 1.0 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 1.0 rifampicin
rpoC 766034 p.His889Thr missense_variant 1.0 rifampicin
rpoC 766042 c.2673C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 1.0 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766634 p.Phe1089Ile missense_variant 1.0 rifampicin
rpoC 766638 p.Lys1090Thr missense_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766694 p.Gln1109Asp missense_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766909 c.3540G>C synonymous_variant 1.0 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 1.0 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766931 p.Ala1188Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>T synonymous_variant 1.0 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 1.0 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 1.0 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775736 c.2745C>G synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 775747 p.Met912Leu missense_variant 0.82 bedaquiline
clofazimine
mmpL5 775748 c.2733T>C synonymous_variant 0.81 bedaquiline
clofazimine
mmpL5 775757 c.2724C>G synonymous_variant 0.58 bedaquiline
clofazimine
mmpL5 775763 c.2718T>G synonymous_variant 0.84 bedaquiline
clofazimine
mmpL5 775769 p.Ala904Gly missense_variant 0.82 bedaquiline
clofazimine
mmpL5 775772 p.Met903Ile missense_variant 0.74 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 775780 p.Thr901Ala missense_variant 0.79 bedaquiline
clofazimine
mmpL5 775793 c.2688C>G synonymous_variant 0.9 bedaquiline
clofazimine
mmpL5 775796 p.Phe895Met missense_variant 0.9 bedaquiline
clofazimine
mmpL5 775814 c.2667C>G synonymous_variant 0.94 bedaquiline
clofazimine
mmpL5 775817 c.2664T>C synonymous_variant 0.97 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.63 bedaquiline
clofazimine
mmpL5 775829 c.2652C>G synonymous_variant 0.76 bedaquiline
clofazimine
mmpL5 775834 p.Ala883Ser missense_variant 0.63 bedaquiline
clofazimine
mmpL5 775838 c.2643G>C synonymous_variant 0.65 bedaquiline
clofazimine
mmpL5 775847 c.2634G>T synonymous_variant 0.77 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 0.69 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.96 bedaquiline
clofazimine
mmpL5 775865 c.2616T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775877 c.2604C>G synonymous_variant 0.73 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.92 bedaquiline
clofazimine
mmpL5 775886 c.2595A>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775892 c.2589C>T synonymous_variant 0.69 bedaquiline
clofazimine
mmpL5 775904 c.2577G>A synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.72 bedaquiline
clofazimine
mmpL5 775915 p.Ala856Ser missense_variant 0.74 bedaquiline
clofazimine
mmpL5 775916 c.2565T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775919 p.Leu854Phe missense_variant 0.38 bedaquiline
clofazimine
mmpL5 775924 c.2557C>T synonymous_variant 0.51 bedaquiline
clofazimine Not assoc w R - Interim
mmpL5 775951 c.2530C>T synonymous_variant 0.8 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.75 bedaquiline
clofazimine
mmpL5 775970 c.2511G>C synonymous_variant 0.98 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 1.0 bedaquiline
clofazimine
mmpL5 775994 p.Ile829Leu missense_variant 0.91 bedaquiline
clofazimine
mmpL5 775997 c.2484T>G synonymous_variant 0.91 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.94 bedaquiline
clofazimine
mmpL5 776005 p.Ile826Leu missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776030 c.2451G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776045 c.2436G>C synonymous_variant 0.78 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776075 c.2406C>G synonymous_variant 0.72 bedaquiline
clofazimine
mmpL5 776081 c.2400G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776084 c.2397C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776087 c.2394C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Leu missense_variant 1.0 bedaquiline
clofazimine
rpsL 781595 c.36T>C synonymous_variant 0.9 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.9 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.9 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.9 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.83 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.85 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.88 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.88 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.88 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.91 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.93 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.97 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.97 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.98 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.96 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.96 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.96 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.95 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.95 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.96 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.96 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.96 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.96 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.96 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.96 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.97 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.97 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.97 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.97 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.96 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.96 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.92 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.94 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.93 linezolid
rplC 800904 c.96G>C synonymous_variant 0.92 linezolid
rplC 800916 c.108A>G synonymous_variant 0.92 linezolid
rplC 800921 p.Arg38Leu missense_variant 0.92 linezolid
rplC 800928 c.120C>T synonymous_variant 0.92 linezolid
rplC 800931 c.123G>C synonymous_variant 0.92 linezolid
rplC 800937 c.129A>G synonymous_variant 0.92 linezolid
rplC 800946 c.138T>C synonymous_variant 0.92 linezolid
rplC 800949 c.141T>C synonymous_variant 0.92 linezolid
rplC 800964 c.156G>C synonymous_variant 0.92 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 801195 c.387G>T synonymous_variant 0.46 linezolid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304567 p.Phe546Tyr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364772 c.360G>A synonymous_variant 1.0 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 1.0 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364796 c.384G>A synonymous_variant 0.93 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.94 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.94 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.94 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.95 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.95 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.96 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.96 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.96 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.96 pyrazinamide
sigE 1364871 c.459C>T synonymous_variant 0.96 pyrazinamide
sigE 1364877 c.465G>T synonymous_variant 0.96 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.96 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.96 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.96 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.92 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.92 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.92 pyrazinamide
sigE 1364931 c.519C>T synonymous_variant 0.91 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.91 pyrazinamide
sigE 1364956 c.544C>T synonymous_variant 0.91 pyrazinamide
sigE 1364962 p.Pro184Ala missense_variant 0.91 pyrazinamide
sigE 1364970 c.558G>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.88 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 0.88 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.88 pyrazinamide
sigE 1364992 p.Pro194Ala missense_variant 0.88 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
sigE 1365003 c.591T>C synonymous_variant 0.89 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.84 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.85 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.81 pyrazinamide
sigE 1365048 c.636G>A synonymous_variant 0.79 pyrazinamide
sigE 1365051 c.639G>A synonymous_variant 0.77 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 0.77 pyrazinamide
sigE 1365069 c.657C>T synonymous_variant 0.75 pyrazinamide
sigE 1365075 c.663G>A synonymous_variant 0.73 pyrazinamide
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.96 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.97 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39_40delTCinsCT non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474016 n.359C>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474022 n.365G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474044 n.387C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1474045 n.388C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1474053 n.396G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474102 n.446_449delAGTA non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474108 n.451C>G non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474110 n.453_454insCGGTG non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631_632delCCinsTCGACT non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474292 n.635T>G non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474417 n.762_765delACGC non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474426 n.769_773delTACGCinsGTA non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAGT non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474960 n.1303delCinsGAT non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474995 n.1338T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474997 n.1340A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475005 n.1348C>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475008 n.1351C>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475015 n.1358C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475017 n.1360_1363delGGTGinsTAGCT non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475382 n.1725A>G non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475395 n.1738T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid Uncertain significance
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
inhA 1673664 c.-538A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673682 c.-520G>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673703 c.-499C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673708 c.-493_-492delCC upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673714 c.-488_-487insT upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673717 c.-485_-484insA upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673745 c.-457G>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673760 c.-442G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673772 c.-430C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673778 c.-424C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673784 c.-418G>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673787 c.-415G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673799 c.-403T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673808 c.-394A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673829 c.-373C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673830 c.-372_-370delAAAinsCGT upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673841 c.-361A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673844 c.-358G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673853 c.-349A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673856 c.-346T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673859 c.-343G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673865 c.-337C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673870 c.-332_-331delGCinsTG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673877 c.-325C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673916 c.-286A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673931 c.-271C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674742 p.Lys181Ala missense_variant 0.92 isoniazid
ethionamide
inhA 1674745 p.Tyr182Ala missense_variant 0.92 isoniazid
ethionamide
inhA 1674753 c.552G>C synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674774 c.573A>C synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674789 c.588G>T synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674792 c.591G>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674795 c.594G>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674804 c.603G>C synonymous_variant 0.9 isoniazid
ethionamide Not assoc w R - Interim
inhA 1674816 c.615T>C synonymous_variant 0.9 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674819 c.618G>A synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674825 c.624C>T synonymous_variant 0.9 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674828 p.Glu209Asp missense_variant 0.9 isoniazid
ethionamide
inhA 1674834 c.633C>G synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674838 p.Ala213Lys missense_variant 0.9 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.92 isoniazid
ethionamide
inhA 1674855 c.654C>G synonymous_variant 0.92 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674876 c.675C>T synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.93 isoniazid
ethionamide
inhA 1674924 c.723G>C synonymous_variant 0.9 isoniazid
ethionamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.91 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.92 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.93 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.95 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.95 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1833709 c.168C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.91 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.95 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.95 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.95 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.95 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.94 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.95 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.95 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.95 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.96 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.95 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834168 c.627C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.91 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.96 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.95 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.97 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.96 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.96 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.83 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.82 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.82 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.82 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.82 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.82 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 1.0 linezolid
katG 2155668 c.444G>C synonymous_variant 0.82 isoniazid
katG 2155674 c.438G>C synonymous_variant 0.82 isoniazid
katG 2155680 c.432G>A synonymous_variant 0.83 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.87 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.87 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.93 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.93 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.93 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.87 isoniazid
katG 2155747 p.Ala122Gly missense_variant 0.87 isoniazid
katG 2155749 c.363C>T synonymous_variant 0.87 isoniazid Not assoc w R - Interim
katG 2155752 c.360C>T synonymous_variant 0.87 isoniazid
katG 2155764 p.His116Glu missense_variant 0.87 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.87 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.87 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.87 isoniazid
katG 2155794 p.Ala106Ser missense_variant 0.9 isoniazid
katG 2155800 c.312G>C synonymous_variant 0.75 isoniazid
katG 2155805 p.Ile103Val missense_variant 0.75 isoniazid Uncertain significance
katG 2155806 c.306T>C synonymous_variant 0.75 isoniazid
katG 2155815 c.297G>C synonymous_variant 0.75 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.87 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.85 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.85 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.82 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.9 isoniazid
kasA 2518636 c.522C>A synonymous_variant 1.0 isoniazid
kasA 2518639 c.525G>T synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Phe missense_variant 1.0 isoniazid
kasA 2518697 p.Cys195Val missense_variant 1.0 isoniazid
kasA 2518708 c.594C>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 1.0 isoniazid
kasA 2518726 c.612G>A synonymous_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 1.0 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 1.0 isoniazid
kasA 2518792 c.678C>G synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>T synonymous_variant 1.0 isoniazid
kasA 2518813 c.699C>T synonymous_variant 1.0 isoniazid
kasA 2518816 c.702C>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>C synonymous_variant 1.0 isoniazid
kasA 2518847 p.Leu245Met missense_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783506 c.537C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783509 c.534C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783516 c.526_527delTCinsAG synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783545 c.498C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.8 capreomycin
Rv2680 2996404 p.Ile100Met missense_variant 0.8 capreomycin
Rv2681 2996407 c.-332C>T upstream_gene_variant 0.8 capreomycin
Rv2681 2996410 c.-329G>C upstream_gene_variant 0.8 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.8 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.8 capreomycin
Rv2752c 3065058 c.1134C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065061 c.1131C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065064 c.1128G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065082 c.1110G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065126 p.Ser356Ala missense_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065130 c.1062A>G synonymous_variant 0.86 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065133 c.1059T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065142 c.1050A>G synonymous_variant 0.86 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.86 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065154 c.1038G>A synonymous_variant 0.84 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065160 c.1032C>T synonymous_variant 0.84 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065166 c.1026C>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065174 c.1018C>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065181 c.1011G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065186 c.1006T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065187 p.Val335Ile missense_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065196 c.996T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065202 c.990T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065210 c.982T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065229 c.963G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065232 c.960T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065235 c.957G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065241 c.951A>G synonymous_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067376 c.570G>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067403 c.543C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073926 c.546G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073971 c.501C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073993 c.478_479delAGinsTC synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074013 c.459C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3074046 c.426G>A synonymous_variant 0.69 para-aminosalicylic_acid
mtrB 3625090 c.1524C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3625095 p.Glu507Lys missense_variant 0.8 rifampicin
bedaquiline
mtrB 3625111 c.1503G>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625122 c.-212C>A upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625135 c.-225A>C upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 0.82 rifampicin
bedaquiline
lpqB 3625156 c.-246G>C upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625165 c.-255G>C upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625168 c.-258G>T upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625183 c.-273G>C upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625186 c.-276T>G upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625204 c.-294G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625207 c.-297C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625243 c.-333T>G upstream_gene_variant 0.83 rifampicin
bedaquiline
mtrB 3625252 c.1362G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625255 c.-345T>C upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625258 c.-348G>T upstream_gene_variant 0.83 rifampicin
bedaquiline
mtrB 3625264 c.1350C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3625267 c.1347T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625279 c.-369C>G upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625285 c.-375G>C upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625297 c.-387C>G upstream_gene_variant 0.8 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.71 rifampicin
bedaquiline
lpqB 3625588 c.-678G>A upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625615 c.-705G>T upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3625623 p.Thr331Ala missense_variant 0.69 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3625636 p.Ala326Glu missense_variant 0.85 rifampicin
bedaquiline
lpqB 3625639 c.-729C>T upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrB 3625645 c.969C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625648 p.Tyr322His missense_variant 0.85 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625657 c.-747C>T upstream_gene_variant 0.86 rifampicin
bedaquiline
lpqB 3625663 c.-753G>A upstream_gene_variant 0.88 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625732 c.882C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.92 rifampicin
bedaquiline
mtrB 3625753 p.Ala287Gln missense_variant 0.92 rifampicin
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 0.92 rifampicin
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625801 c.-891G>T upstream_gene_variant 0.88 rifampicin
bedaquiline
lpqB 3625804 c.-896_-894delAGGinsCGC upstream_gene_variant 0.88 rifampicin
bedaquiline
lpqB 3625822 c.-912C>T upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrA 3626749 c.601C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626753 c.-140G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGT upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626786 c.-173A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626792 c.-179G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626843 c.-230G>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626864 c.-253_-251delTTGinsCTC upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626894 c.-281C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626906 p.Asn148Gln missense_variant 1.0 rifampicin
bedaquiline
mtrA 3626909 c.441C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrA 3626912 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626939 c.411A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626949 p.Ala134Asn missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626962 p.Met130Leu missense_variant 1.0 rifampicin
bedaquiline
mtrA 3626969 c.381C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626978 p.Asp124Glu missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
mtrB 3626999 c.-386G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627002 c.-389G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627005 c.-392G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627032 c.-419G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627041 p.Ile103Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627044 c.-431C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627062 c.-449G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.92 rifampicin
bedaquiline
mtrB 3627110 c.-497G>C upstream_gene_variant 0.92 rifampicin
bedaquiline
mtrB 3627137 c.-526_-524delTTGinsCTC upstream_gene_variant 0.8 rifampicin
bedaquiline
rpoA 3877587 c.921A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.81 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.9 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.9 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.88 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.87 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.92 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.92 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.94 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.94 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877770 c.735_738delGTCAinsCAGC synonymous_variant 0.92 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.93 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.91 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.9 rifampicin
rpoA 3877875 c.633T>A synonymous_variant 0.88 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.86 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.85 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.82 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.84 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.86 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>C synonymous_variant 0.86 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 0.87 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.87 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.87 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.87 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.87 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.87 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>G synonymous_variant 0.87 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.9 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.91 rifampicin
rpoA 3878061 c.447G>A synonymous_variant 0.91 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.88 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.88 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.85 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.88 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.9 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.9 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.89 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>A synonymous_variant 0.91 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.91 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878238 c.270C>T synonymous_variant 0.92 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 0.92 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.92 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.92 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.9 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.89 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>A synonymous_variant 0.88 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.88 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.88 rifampicin
rpoA 3878352 c.156C>G synonymous_variant 0.91 rifampicin
rpoA 3878358 c.150C>G synonymous_variant 0.91 rifampicin
rpoA 3878361 c.147G>A synonymous_variant 0.91 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.91 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.91 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.91 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.91 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.91 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878400 c.108T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 0.88 rifampicin
ddn 3986615 c.-229C>A upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986616 c.-228_-227delAGinsGC upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986622 c.-222C>T upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986633 c.-211C>T upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.96 pretomanid
delamanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.95 pretomanid
delamanid
ddn 3986667 c.-177_-175delCTCinsACG upstream_gene_variant 0.95 pretomanid
delamanid
ddn 3986696 c.-148G>C upstream_gene_variant 0.91 pretomanid
delamanid
ddn 3986699 c.-145C>A upstream_gene_variant 0.9 pretomanid
delamanid
clpC1 4038551 c.2154C>G synonymous_variant 0.92 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.94 pyrazinamide
clpC1 4038584 c.2121G>A synonymous_variant 0.96 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.97 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.97 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.97 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.97 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.88 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.9 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.92 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.93 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.93 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.93 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039100 c.1605C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039118 c.1587C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039320 p.Ala462Gly missense_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039361 c.1344C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.94 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.95 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.95 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.94 pyrazinamide
clpC1 4039457 c.1248C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039730 c.975C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039784 c.921C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039883 c.822G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.97 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>T synonymous_variant 0.88 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.88 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.91 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040192 c.513C>G synonymous_variant 0.84 pyrazinamide
clpC1 4040195 c.510G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040213 p.Ser164Asn missense_variant 0.82 pyrazinamide
clpC1 4040219 c.486C>G synonymous_variant 0.85 pyrazinamide
clpC1 4040225 c.480A>T synonymous_variant 0.86 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.8 pyrazinamide
clpC1 4040237 c.468C>G synonymous_variant 0.87 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.88 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.86 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040306 c.399G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040324 c.381G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040335 c.370C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040336 c.369G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.92 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.92 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 1.0 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040618 c.87C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
glpK 4138661 c.1095T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138670 c.1086G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138676 c.1080T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138696 p.Pro354Thr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138697 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138703 c.1053C>G synonymous_variant 0.87 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138727 c.1029C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138747 c.1009C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138763 c.993G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138769 c.987G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138778 c.978C>A synonymous_variant 0.84 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138781 c.975G>T synonymous_variant 0.84 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138799 c.957T>G synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138808 c.948G>T synonymous_variant 0.81 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138817 p.Ala313Ser missense_variant 0.8 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138822 p.Asn312Asp missense_variant 0.8 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138823 c.933G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138829 c.927A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138847 c.909A>C synonymous_variant 0.75 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138853 c.903C>A synonymous_variant 0.75 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139242 c.514T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139243 c.513A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139258 c.498C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139262 p.Ala165Asp missense_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139263 c.492_493insC frameshift_variant 0.73 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4139266 c.489delC frameshift_variant 0.73 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4139273 c.483A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139276 p.Asp160Glu missense_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139285 p.Glu157Asp missense_variant 0.79 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139288 c.468G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139300 p.Leu152Ile missense_variant 0.8 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139312 c.444T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139318 c.438T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139321 c.435T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139324 c.432A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139327 c.429G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139336 c.420C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139339 c.417G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139348 c.408C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139356 p.Leu134Val missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139359 p.Asn133Asp missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139360 c.396A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139363 c.393T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139366 c.390T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139372 c.384A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139381 c.375G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139384 p.Ser124Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139387 c.369G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139408 c.348T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139417 c.339A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139420 c.336T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139423 c.333G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139431 p.Tyr109His missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embB 4247398 c.885G>A synonymous_variant 1.0 ethambutol
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247407 c.894G>C synonymous_variant 1.0 ethambutol
embB 4247426 p.Gly305Gln missense_variant 1.0 ethambutol
embB 4247434 c.921C>G synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>C synonymous_variant 1.0 ethambutol
embB 4247440 c.927C>G synonymous_variant 1.0 ethambutol
embB 4247449 c.936C>T synonymous_variant 1.0 ethambutol
embB 4247455 c.942C>T synonymous_variant 1.0 ethambutol
embB 4247464 c.951C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 1.0 ethambutol
embB 4247527 c.1014G>C synonymous_variant 1.0 ethambutol
embB 4247536 c.1023C>G synonymous_variant 1.0 ethambutol
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248112 c.1599C>G synonymous_variant 1.0 ethambutol
embB 4248118 c.1605T>C synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248133 c.1620C>G synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 p.Leu544Ile missense_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.97 ethambutol
embB 4248167 p.Thr552Ala missense_variant 0.97 ethambutol
embB 4248170 p.Ala553Ser missense_variant 0.97 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.97 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.97 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.97 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.97 ethambutol Uncertain significance
embB 4248220 c.1707A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.96 ethambutol Uncertain significance
embB 4248233 c.1720C>T synonymous_variant 0.96 ethambutol
embB 4248242 p.Val577Ile missense_variant 0.95 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.95 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.94 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.94 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.93 ethambutol