TB-Profiler result

Run: ERR4769474

Summary

Run ID: ERR4769474

Sample name:

Date: 2024-10-05T04:33:08.864945

Number of reads: 478073

Percentage reads mapped: 11.28

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser140Asn Uncertain significance Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
katG 2155693 p.Ser140Asn missense_variant 0.91 isoniazid Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 568 p.Ala190Ser missense_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 576 c.576G>T synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>C synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 1.0 isoniazid
dnaA 594 c.594C>G synonymous_variant 1.0 isoniazid
dnaA 597 c.597C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>G synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 610 c.610C>T synonymous_variant 1.0 isoniazid
dnaA 627 c.627G>A synonymous_variant 1.0 isoniazid
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 642 c.642G>A synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 648 c.648C>T synonymous_variant 1.0 isoniazid
dnaA 654 c.654A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 666 c.666C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6199 c.960C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6204 p.Ser322Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6208 c.969G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6277 c.1038C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6283 c.1044C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6324 c.1085_1086insGTCC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6327 c.1090_1093delGAAC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6352 c.1113C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6398 p.Val387Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6547 c.-755T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6589 c.-713G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6597 p.Ser453Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554_1555delTAinsCCTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6796 c.1558_1559delGG frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6881 c.-421_-419delTTGinsCTC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6896 p.Arg553Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7415 c.114C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7436 c.135C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7506 p.Ser69Gly missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7514 c.213C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7556 c.255C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCTT synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7868 p.Ile189Met missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8129 c.828T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8165 c.864C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8261 c.960C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8273 c.972C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8279 c.978G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8357 c.1056G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8363 c.1062C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8369 c.1068G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8405 c.1104C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8580 p.Ile427Val missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8798 p.Ile499Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8888 c.1587C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8909 c.1608C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8915 c.1614A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Asn missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9300 p.Ala667Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9329 c.2028C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9332 p.Asn677Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491508 c.726A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491509 c.727T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491535 c.753G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491553 c.771G>A synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491560 p.His260Thr missense_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491564 p.Ser261Asn missense_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491569 p.Asp263His missense_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491578 p.Ile266Leu missense_variant 0.73 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491603 p.Ala274Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491631 c.849C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491640 c.858G>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491646 c.864G>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575521 c.174A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575527 c.180G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575539 c.192C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575548 c.201C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 1.0 isoniazid
ethionamide
mshA 575569 c.222A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575572 c.225T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575576 c.229C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575582 p.Leu79Met missense_variant 1.0 isoniazid
ethionamide
mshA 575587 c.240C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575590 c.243T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575593 c.246G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575596 c.249C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575597 p.Ile84Val missense_variant 1.0 isoniazid
ethionamide
mshA 575620 c.273G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575626 c.279C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575627 p.Ala94Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575635 c.288A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575641 c.294A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575647 c.300G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575665 c.318G>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575668 c.321G>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575683 c.336G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575686 c.339G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358_360delTTGinsCTC synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575722 c.375G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575728 c.381C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575732 c.385_387delCTTinsTTG synonymous_variant 1.0 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 575752 c.405G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575755 c.408G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575767 c.420G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575770 c.423G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 1.0 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575851 c.504C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575864 c.517_519delTTGinsCTT synonymous_variant 0.97 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575887 c.540G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575902 c.555C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575905 c.558G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575914 c.567C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575917 p.Asp190Glu missense_variant 1.0 isoniazid
ethionamide
mshA 575924 p.Gly193Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575932 c.585G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575938 c.591G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575945 p.Thr200Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575953 c.606G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575965 c.618C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
ccsA 620583 c.693G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620586 c.696C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620607 c.717T>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620613 c.723C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620619 c.729G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620712 c.822G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620760 c.870C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620769 c.879C>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620781 c.891C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620796 c.906C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620802 c.912C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620808 c.918T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620818 p.Val310Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
Rv0565c 657592 c.-122A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657601 c.-131A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657604 c.-134G>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657653 c.-183C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657656 c.-186C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657670 c.-200A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657703 c.-233C>A upstream_gene_variant 1.0 ethionamide
nusG 734421 c.168A>C synonymous_variant 0.91 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.92 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.94 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.95 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.95 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.95 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>G synonymous_variant 0.95 rifampicin
nusG 734484 c.231C>T synonymous_variant 0.96 rifampicin
nusG 734499 c.246G>C synonymous_variant 0.97 rifampicin
nusG 734508 c.255C>G synonymous_variant 0.98 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.97 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.97 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734595 p.Asp114Glu missense_variant 1.0 rifampicin
nusG 734596 c.343_345delTTGinsCTC synonymous_variant 1.0 rifampicin
nusG 734600 p.Thr116Asn missense_variant 1.0 rifampicin Uncertain significance
nusG 734607 p.Asp118Glu missense_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734615 p.Ala121Gly missense_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734637 c.384G>C synonymous_variant 1.0 rifampicin
rpoB 760046 c.240G>C synonymous_variant 1.0 rifampicin
rpoB 760059 p.Tyr85Thr missense_variant 1.0 rifampicin
rpoB 760067 c.261G>C synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.96 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Asn missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 1.0 rifampicin
rpoB 760490 c.684C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760522 p.Ser239Thr missense_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 c.757delCinsAT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoB 760566 p.Ser254Ala missense_variant 1.0 rifampicin
rpoB 760567 c.762delG frameshift_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760596 p.Thr264Ser missense_variant 1.0 rifampicin
rpoB 760607 c.801G>C synonymous_variant 1.0 rifampicin
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoB 760625 c.819C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 1.0 rifampicin
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760973 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760979 c.1173G>A synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.96 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.96 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.97 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761217 p.Pro471Ser missense_variant 0.97 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.97 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.97 rifampicin
rpoB 761354 c.1548C>G synonymous_variant 0.97 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.97 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.97 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.97 rifampicin
rpoB 761381 c.1575G>C synonymous_variant 0.97 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.95 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.94 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>T synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 1.0 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761847 p.Cys681Arg missense_variant 1.0 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761868 p.Asp688Gln missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 1.0 rifampicin
rpoB 761882 c.2076C>G synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761892 p.Ile696Val missense_variant 1.0 rifampicin
rpoB 761903 c.2097T>C synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 p.Asp703Gln missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762134 c.2328C>T synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.97 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.97 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 1.0 rifampicin
rpoB 762359 c.2553C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762923 c.3117C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763040 c.3234C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 0.99 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.99 rifampicin
rpoC 763082 c.-288C>G upstream_gene_variant 0.99 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.99 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763170 c.-200C>T upstream_gene_variant 1.0 rifampicin
rpoC 763187 c.-183C>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.95 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.97 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.97 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.97 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.97 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.97 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 0.97 rifampicin
rpoC 763251 c.-119C>T upstream_gene_variant 0.97 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.96 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.96 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.96 rifampicin
rpoC 763274 c.-96G>C upstream_gene_variant 0.96 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763289 c.-81C>G upstream_gene_variant 0.92 rifampicin
rpoC 763402 c.33C>G synonymous_variant 1.0 rifampicin
rpoC 763411 c.42T>C synonymous_variant 1.0 rifampicin
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763420 c.51G>C synonymous_variant 1.0 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763429 c.60C>T synonymous_variant 1.0 rifampicin
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 1.0 rifampicin
rpoC 763435 c.66A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763501 c.132C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>T synonymous_variant 1.0 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>T synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763786 c.417C>G synonymous_variant 1.0 rifampicin
rpoC 763787 p.Asp140Asn missense_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763840 c.471G>C synonymous_variant 1.0 rifampicin
rpoC 763844 p.Arg159Lys missense_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763861 c.492C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 1.0 rifampicin
rpoC 763921 c.552G>C synonymous_variant 1.0 rifampicin
rpoC 763930 c.561G>A synonymous_variant 1.0 rifampicin
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>G synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764353 c.984G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764395 c.1026C>T synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCGT synonymous_variant 1.0 rifampicin
rpoC 764429 c.1060C>T synonymous_variant 1.0 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>C synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 1.0 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764843 p.Ala492Ser missense_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 1.0 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>T synonymous_variant 1.0 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764926 c.1557C>T synonymous_variant 1.0 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>T synonymous_variant 1.0 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.96 rifampicin
rpoC 765083 p.Arg572Lys missense_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 1.0 rifampicin
rpoC 765129 p.Tyr587Phe missense_variant 1.0 rifampicin
rpoC 765403 c.2034_2035insAT frameshift_variant 1.0 rifampicin
rpoC 765406 c.2037G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765407 c.2039_2040delGT frameshift_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765419 p.Val684Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765452 p.Ala695Arg missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 1.0 rifampicin Uncertain significance
rpoC 765493 c.2124G>C synonymous_variant 1.0 rifampicin
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765547 c.2178C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 1.0 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 1.0 rifampicin
rpoC 765779 p.Asp804Lys missense_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765812 c.2443C>A synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765970 c.2601C>G synonymous_variant 1.0 rifampicin
rpoC 765973 c.2604C>G synonymous_variant 1.0 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 1.0 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766034 p.His889Asn missense_variant 1.0 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766054 c.2685C>T synonymous_variant 1.0 rifampicin
rpoC 766061 p.Val898Asn missense_variant 1.0 rifampicin
rpoC 766067 p.Glu900Thr missense_variant 1.0 rifampicin
rpoC 766081 c.2712T>G synonymous_variant 1.0 rifampicin
rpoC 766083 p.Ala905Gly missense_variant 1.0 rifampicin
rpoC 766085 p.Pro906Ala missense_variant 1.0 rifampicin Not assoc w R
rpoC 766108 c.2739C>T synonymous_variant 1.0 rifampicin
rpoC 766112 p.Tyr915His missense_variant 1.0 rifampicin
rpoC 766115 p.Ile916Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 766120 c.2751A>G synonymous_variant 1.0 rifampicin
rpoC 766297 c.2928G>C synonymous_variant 1.0 rifampicin
rpoC 766299 p.Thr977Met missense_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.98 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766429 c.3060C>G synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 1.0 rifampicin
rpoC 766516 c.3147C>G synonymous_variant 1.0 rifampicin
rpoC 766517 p.Thr1050Ser missense_variant 1.0 rifampicin
rpoC 766525 c.3156G>C synonymous_variant 0.98 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 1.0 rifampicin
rpoC 766624 c.3255G>T synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 1.0 rifampicin
rpoC 766634 p.Phe1089Ile missense_variant 1.0 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766753 c.3384C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766776 p.Arg1136His missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766961 p.Gly1198Met missense_variant 1.0 rifampicin
rpoC 766978 c.3609C>A synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767179 c.3810C>T synonymous_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>T synonymous_variant 1.0 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767269 c.3900C>G synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775832 c.2649C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775847 c.2634G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775850 c.2631C>T synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775862 c.2619G>C synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 775865 c.2616T>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775880 c.2600_2601delACinsGCGG frameshift_variant&missense_variant 0.7 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 775882 p.Asn867Tyr missense_variant 0.7 bedaquiline
clofazimine
mmpL5 775889 c.2592C>G synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 775892 c.2589C>T synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 775904 c.2577G>A synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775915 p.Ala856Ser missense_variant 0.88 bedaquiline
clofazimine
mmpL5 775916 c.2565T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775922 c.2559G>C synonymous_variant 0.81 bedaquiline
clofazimine
mmpL5 775946 c.2535C>G synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 775951 c.2530C>T synonymous_variant 0.95 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.81 bedaquiline
clofazimine
mmpL5 775975 p.Leu836Met missense_variant 0.98 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.98 bedaquiline
clofazimine
mmpL5 775991 c.2490G>A synonymous_variant 0.98 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.98 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.92 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.98 bedaquiline
clofazimine
mmpL5 776021 c.2460G>A synonymous_variant 0.82 bedaquiline
clofazimine
mmpL5 776024 c.2457G>C synonymous_variant 0.98 bedaquiline
clofazimine
mmpL5 776030 c.2451G>T synonymous_variant 0.91 bedaquiline
clofazimine
mmpL5 776039 c.2442C>G synonymous_variant 0.92 bedaquiline
clofazimine
mmpL5 776060 c.2421C>G synonymous_variant 0.82 bedaquiline
clofazimine
mmpL5 776072 c.2409C>G synonymous_variant 0.96 bedaquiline
clofazimine
mmpL5 776075 c.2406C>G synonymous_variant 0.84 bedaquiline
clofazimine
mmpL5 776078 p.Ala801Ser missense_variant 0.83 bedaquiline
clofazimine
mmpL5 776081 c.2400G>C synonymous_variant 0.83 bedaquiline
clofazimine
mmpL5 776087 c.2394C>G synonymous_variant 0.83 bedaquiline
clofazimine
mmpL5 776093 c.2388C>A synonymous_variant 0.88 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776104 p.Ile793Leu missense_variant 0.94 bedaquiline
clofazimine
mmpL5 776120 c.2361C>T synonymous_variant 0.9 bedaquiline
clofazimine
mmpL5 777570 p.Gly304His missense_variant 0.75 bedaquiline
clofazimine
mmpL5 777572 c.909C>T synonymous_variant 0.92 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 777578 c.903C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777596 c.885G>A synonymous_variant 0.73 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 777614 c.866_867insAAGGG frameshift_variant 0.73 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777620 c.861A>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777623 c.858G>A synonymous_variant 0.75 bedaquiline
clofazimine
mmpL5 777638 c.843G>C synonymous_variant 0.71 bedaquiline
clofazimine
mmpL5 777662 c.819C>T synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777665 c.816G>C synonymous_variant 0.83 bedaquiline
clofazimine
mmpL5 777671 c.810G>C synonymous_variant 0.82 bedaquiline
clofazimine
rpsL 781559 c.-1G>C upstream_gene_variant 1.0 streptomycin
rpsL 781572 p.Gln5Asn missense_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>G synonymous_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781676 c.117C>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>T synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.98 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781889 c.330C>T synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781895 c.336G>A synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>G synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800531 c.-278T>C upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>G upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800564 c.-245C>G upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800780 c.-29C>G upstream_gene_variant 1.0 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 1.0 linezolid
fbiC 1304496 c.1566T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304499 c.1569T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304502 c.1572G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304508 p.Glu526Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304520 c.1590A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304523 c.1593G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603_1605delTTGinsCTT synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304655 c.1725C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304658 c.1728C>G synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304763 c.1833C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304769 c.1839C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304809 p.Ser627Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304868 c.1938G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304894 p.Gly655Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304896 c.1966C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304915 p.Asp662Gly missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304917 p.Thr663Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304922 c.1992C>T synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1304925 c.1995G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1304952 c.2022C>T synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1305282 c.2352T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305288 c.2358C>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305297 c.2367G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305303 c.2373T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305306 c.2376A>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305309 c.2379G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305310 p.Arg794Glu missense_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305315 c.2385C>T synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305318 c.2388C>T synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305330 c.2400C>G synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1305331 p.Glu801Gln missense_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1305351 c.2421G>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1305357 c.2427C>G synonymous_variant 0.94 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305369 c.2439G>A synonymous_variant 0.94 pretomanid
delamanid
clofazimine
sigE 1364688 c.276C>G synonymous_variant 1.0 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364715 c.303G>T synonymous_variant 1.0 pyrazinamide
sigE 1364718 c.306C>T synonymous_variant 1.0 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364757 c.345G>A synonymous_variant 1.0 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355_357delAGGinsCGC synonymous_variant 1.0 pyrazinamide
sigE 1364772 c.360G>C synonymous_variant 1.0 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364859 c.447C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 1.0 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 1.0 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 1.0 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 1.0 pyrazinamide
sigE 1364964 c.552T>G synonymous_variant 1.0 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>A synonymous_variant 0.85 pyrazinamide
sigE 1364980 c.568_570delTTGinsCTC synonymous_variant 0.92 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.92 pyrazinamide
sigE 1364988 c.576G>A synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
sigE 1364994 c.582G>C synonymous_variant 0.92 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.93 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.93 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.93 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.93 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.93 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.92 pyrazinamide
atpE 1461042 c.-2delA upstream_gene_variant 1.0 bedaquiline
atpE 1461050 c.6C>T synonymous_variant 1.0 bedaquiline
atpE 1461056 c.12T>A synonymous_variant 1.0 bedaquiline
atpE 1461089 c.45G>C synonymous_variant 1.0 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 1.0 bedaquiline
atpE 1461113 c.69C>T synonymous_variant 1.0 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461153 p.Ser37Ala missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461167 c.123G>C synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 1.0 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 1.0 bedaquiline
atpE 1461188 c.144G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 1.0 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
rrs 1471508 n.-338T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471514 n.-332A>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471517 n.-329T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471521 n.-325T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472451 n.606C>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473728 n.71A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.631_635delCCTTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 0.37 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474295 n.638C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474297 n.640C>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474299 n.642_653delCCGGAGGAGGGTinsTTTGATGTGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474420 n.764_768delGCGCA non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474427 n.770A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474428 n.771C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474430 n.773C>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474434 n.778dupG non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474945 n.1288C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474952 n.1296delC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474960 n.1305dupT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474971 n.1315delG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475232 n.1575A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475286 n.1629T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475297 n.1640C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475614 n.1957A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105_2106delGCinsTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476755 n.3098G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673565 c.-637G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673568 c.-634C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673577 c.-625C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
inhA 1673583 c.-619A>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673589 c.-613A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673592 c.-610G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673596 c.-606A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673616 c.-586A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673637 c.-565C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673646 c.-556T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673652 c.-550C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673657 c.-545_-544delCGinsAA upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673691 c.-511G>A upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
inhA 1673706 c.-496C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsCA upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673733 c.-469G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673760 c.-442G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673787 c.-415G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673805 c.-397G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673808 c.-394A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673901 c.-301A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673916 c.-286A>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673931 c.-271C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673952 c.-250G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673962 c.-240_-239delAAinsGG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673967 c.-235G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673979 c.-223G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673982 c.-220G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674015 c.-187C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674037 c.-165C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674048 c.-154G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674049 c.-153_-151delCAAinsGAG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674060 c.-142A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674063 c.-139G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674083 c.-119_-118delCCinsAG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674098 c.-104T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674102 c.-100C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674117 c.-85C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674123 c.-79T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674136 c.-66T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674144 c.-58G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674387 c.186A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674399 c.198A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674402 c.201C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674405 p.Glu68Asp missense_variant 1.0 isoniazid
ethionamide
inhA 1674419 p.Ser73Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674421 c.220T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674428 p.Gly76Asp missense_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674443 p.Ala81Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674450 c.249G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674452 p.Ala84Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674462 c.261G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674471 c.270G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674474 c.273G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674507 c.306G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674514 p.Ile105Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.98 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674579 c.378G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674600 c.399G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674601 p.Leu134Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674610 p.Ile137Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674628 p.Ser143Gly missense_variant 1.0 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674658 c.457C>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674669 c.468G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674672 c.471C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674703 c.502_504delTTGinsCTC synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674742 p.Lys181Gln missense_variant 1.0 isoniazid
ethionamide
inhA 1674745 p.Tyr182Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674771 c.570C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674783 c.582C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674789 c.588G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674792 c.591G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674816 c.615T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674825 c.624C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674828 p.Glu209Asp missense_variant 1.0 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 1.0 isoniazid
ethionamide
inhA 1674858 c.657G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674876 c.675C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674883 p.Ile228Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 1.0 isoniazid
ethionamide
inhA 1674909 c.708G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833554 p.Thr5Ser missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833607 c.66T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833682 c.141C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833700 c.159C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833799 c.258C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 1.0 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834298 p.Gln253Thr missense_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834600 c.1059G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834678 c.1137C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 1.0 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834787 p.Ala416Ser missense_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853401 c.-205A>G upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
katG 2155655 p.Lys153Gln missense_variant 1.0 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 0.91 isoniazid
katG 2155677 c.435C>T synonymous_variant 0.91 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.91 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.91 isoniazid
katG 2155716 c.396T>C synonymous_variant 0.91 isoniazid
katG 2155719 c.393G>C synonymous_variant 0.9 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.9 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.9 isoniazid
katG 2155735 p.Met126Ala missense_variant 0.9 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.9 isoniazid
katG 2155752 c.360C>T synonymous_variant 0.9 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517980 c.-135C>G upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2518013 c.-102G>A upstream_gene_variant 1.0 isoniazid
kasA 2518016 c.-99A>G upstream_gene_variant 1.0 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518624 c.510C>G synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>C synonymous_variant 1.0 isoniazid
kasA 2518636 c.522C>G synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 1.0 isoniazid
kasA 2518663 c.549T>G synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.97 isoniazid
kasA 2518697 p.Cys195Val missense_variant 1.0 isoniazid
kasA 2518705 c.591T>C synonymous_variant 1.0 isoniazid
kasA 2518708 c.594C>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518765 c.651G>C synonymous_variant 1.0 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 1.0 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.94 isoniazid
kasA 2518792 c.678C>G synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518811 p.Asp233Asn missense_variant 1.0 isoniazid
kasA 2518822 c.708C>G synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518847 p.Leu245Met missense_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2519203 c.1089C>T synonymous_variant 1.0 isoniazid
kasA 2519224 c.1110C>A synonymous_variant 1.0 isoniazid
kasA 2519242 c.1128C>G synonymous_variant 1.0 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 1.0 isoniazid
kasA 2519260 c.1146T>C synonymous_variant 1.0 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 1.0 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
kasA 2519278 c.1164A>G synonymous_variant 1.0 isoniazid
kasA 2519281 c.1167G>A synonymous_variant 1.0 isoniazid
kasA 2519284 c.1170C>G synonymous_variant 1.0 isoniazid
kasA 2519293 c.1179T>C synonymous_variant 1.0 isoniazid
kasA 2519298 p.Arg395Gln missense_variant 1.0 isoniazid
kasA 2519305 c.1191A>C synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783503 c.540G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783516 c.526_527delTCinsAG synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783524 c.519G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783527 p.Lys172Arg missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783575 c.468G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.96 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783596 c.447C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783626 p.Ala139Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783662 c.381G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin