TB-Profiler result

Run: ERR212121
Summary

Run ID: ERR212121

Sample name:

Date: 2024-04-16T09:22:57.398989

Number of reads: 1064752

Percentage reads mapped: 22.9

Median coverage: 23.0

Strain: lineage4.9;lineage6.3

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.09
lineage4.1.4 Euro-American None 0.07
lineage6.3 West-Africa 2 RD702 0.08
La1.2.BCG M.bovis None 0.09
lineage4.3.2.1 Euro-American (LAM) RD761 0.13
lineage3.1.2.2 East-African-Indian RD750 0.28
lineage6.1.3 West-Africa 2 RD702 0.14
lineage4.9 Euro-American (H37Rv-like) None 0.66
La1.8.2 M.bovis None 0.09
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.Ala388Gly Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.4_6delGCAinsCT Assoc w R
kanamycin
cycloserine
ethionamide ethA c.1129_1131delATCinsCG Assoc w R
c.571_573delGTGinsAT Assoc w R
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.973_975delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.691_693delTACinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1207_1209delGCGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1549_1551delCTTinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1567_1569delCCTinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1945_1947delATTinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD c.127_129delCTCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.358_360delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.388_390delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.220_222delATTinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.244_246delGCGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491755 c.973_975delCAGinsGA frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303621 c.691_693delTACinsCT frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304137 c.1207_1209delGCGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304479 c.1549_1551delCTTinsTG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304497 c.1567_1569delCCTinsGC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304875 c.1945_1947delATTinsGC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
tlyA 1917943 c.4_6delGCAinsCT frameshift_variant&missense_variant 1.0 capreomycin Assoc w R
katG 2155108 p.Ile335Thr missense_variant 0.88 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.88 isoniazid Assoc w R High-level resistance
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
fbiD 3339244 c.127_129delCTCinsTG frameshift_variant&missense_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD 3339475 c.358_360delTTAinsCG frameshift_variant&missense_variant 0.91 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD 3339505 c.388_390delTCGinsGC frameshift_variant&missense_variant 0.93 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987063 c.220_222delATTinsGG frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987087 c.244_246delGCGinsTC frameshift_variant&missense_variant 0.98 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247676 p.Ala388Gly missense_variant 0.92 ethambutol Mutation from literature
ethA 4326343 c.1129_1131delATCinsCG frameshift_variant&missense_variant 0.69 ethionamide Assoc w R
ethA 4326901 c.571_573delGTGinsAT frameshift_variant&missense_variant 0.97 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 22 p.Gly8Thr missense_variant 1.0 isoniazid
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 138 c.138T>G synonymous_variant 1.0 isoniazid
dnaA 144 c.144C>G synonymous_variant 1.0 isoniazid
dnaA 150 c.150C>G synonymous_variant 1.0 isoniazid
dnaA 156 c.156G>A synonymous_variant 1.0 isoniazid
dnaA 159 c.159A>G synonymous_variant 1.0 isoniazid
dnaA 187 c.187_189delTTAinsCG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 192 c.192C>G synonymous_variant 1.0 isoniazid
dnaA 204 c.204C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 207 c.207T>C synonymous_variant 1.0 isoniazid
dnaA 213 c.213A>G synonymous_variant 1.0 isoniazid
dnaA 219 c.219A>G synonymous_variant 1.0 isoniazid
dnaA 510 c.510T>C synonymous_variant 0.93 isoniazid
dnaA 522 c.522T>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 0.92 isoniazid
dnaA 528 c.528G>C synonymous_variant 0.93 isoniazid
dnaA 534 c.534T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 540 c.540C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 564 c.564C>G synonymous_variant 0.98 isoniazid
dnaA 570 c.570C>A synonymous_variant 0.98 isoniazid
dnaA 571 c.571_573delTTGinsCC frameshift_variant&missense_variant 0.98 isoniazid Uncertain significance
dnaA 576 c.576G>C synonymous_variant 0.98 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 0.98 isoniazid
dnaA 600 c.600T>G synonymous_variant 0.98 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.98 isoniazid
dnaA 618 c.618C>A synonymous_variant 0.97 isoniazid
dnaA 627 c.627G>A synonymous_variant 1.0 isoniazid
dnaA 633 c.633T>C synonymous_variant 0.94 isoniazid
dnaA 648 c.648C>T synonymous_variant 0.94 isoniazid
dnaA 652 c.652_654delCTAinsTG frameshift_variant&stop_gained 0.94 isoniazid Uncertain significance
dnaA 663 c.663A>C synonymous_variant 0.94 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.94 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 693 c.693A>G synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.89 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.89 isoniazid
dnaA 717 c.717C>T synonymous_variant 0.94 isoniazid
dnaA 723 c.723A>G synonymous_variant 0.95 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 0.89 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.94 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.95 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.96 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 798 c.798C>T synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.97 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.94 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.97 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.94 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.97 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.97 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 0.97 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.97 isoniazid
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.97 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.96 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.96 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.96 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.97 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.95 isoniazid
dnaA 957 c.957A>G synonymous_variant 0.94 isoniazid
dnaA 960 c.960C>G synonymous_variant 0.91 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.94 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.92 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.89 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 996 c.996A>G synonymous_variant 0.96 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 0.96 isoniazid
dnaA 1050 c.1050G>T synonymous_variant 0.96 isoniazid
dnaA 1059 c.1059C>G synonymous_variant 0.98 isoniazid
dnaA 1065 c.1065C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.97 isoniazid
dnaA 1071 c.1071C>A synonymous_variant 0.99 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.97 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.99 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.99 isoniazid
dnaA 1125 c.1125G>T synonymous_variant 0.99 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 0.97 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.99 isoniazid
dnaA 1146 c.1146C>T synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.99 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.99 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.99 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.98 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.98 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.97 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.97 isoniazid
dnaA 1239 c.1239G>C synonymous_variant 0.97 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.98 isoniazid
dnaA 1281 c.1281C>A synonymous_variant 0.98 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.98 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.96 isoniazid
dnaA 1311 c.1311C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1317 c.1317A>G synonymous_variant 0.99 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 1.0 isoniazid
dnaA 1350 c.1350G>A synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>C synonymous_variant 0.98 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.98 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.98 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.96 isoniazid
dnaA 1404 c.1404T>G synonymous_variant 0.97 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.97 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.97 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.97 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.97 isoniazid
dnaA 1461 c.1461C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1464 c.1464T>C synonymous_variant 0.97 isoniazid
dnaA 1470 c.1470C>G synonymous_variant 1.0 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1482 c.1482C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1485 c.1485A>G synonymous_variant 1.0 isoniazid
dnaA 1497 c.1497T>G synonymous_variant 1.0 isoniazid
dnaA 1512 c.1512C>G synonymous_variant 1.0 isoniazid
gyrB 5858 p.Asn207His missense_variant 0.94 levofloxacin
moxifloxacin
gyrB 5866 c.627C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5869 c.630C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5880 p.Thr214Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 5882 c.643_645delCAAinsAC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5887 p.Asp216Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 5893 c.654C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5905 c.666G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6047 p.Ala270Pro missense_variant 0.82 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6056 c.817_818delAGinsTC synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6076 c.837C>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6078 p.Gly280Asp missense_variant 0.8 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6142 c.903G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6145 c.906C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6196 c.957C>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.95 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6349 c.-953G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6577 c.-725T>A upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6865 c.-437G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6886 c.-416C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6887 c.-415C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6892 c.-410C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7344 p.Ile15Val missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7349 c.48A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7427 c.126G>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7466 c.165G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7688 c.387C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7808 c.507G>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 c.618G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8183 c.882C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8216 c.915G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8369 c.1068G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8435 c.1134C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8576 c.1275C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 p.Glu429Asp missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8738 c.1437G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8836 p.Ala512Val missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8885 c.1584C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8921 c.1620C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8924 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8978 c.1677C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9056 c.1755C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCT frameshift_variant&synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.98 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Glu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9184 p.Arg628Gln missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9263 c.1962C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9281 c.1980C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.94 isoniazid
Rv0010c 13884 c.-326A>G upstream_gene_variant 0.95 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.96 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.96 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.97 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.97 isoniazid
fgd1 490777 c.-6G>T upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490781 c.-2T>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490782 c.-1G>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490803 c.21T>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490899 c.117C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491058 c.276C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491112 c.330G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491532 c.750G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491623 p.Ala281Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491712 c.930T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491721 c.939A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491727 c.945T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491739 c.957G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
fgd1 491758 p.Ser326Lys missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491769 c.987A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
mshA 574604 c.-744C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574607 c.-741G>T upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574616 c.-732G>T upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574631 c.-717C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574640 c.-708G>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.98 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.98 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574698 c.-650G>A upstream_gene_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574712 c.-636A>G upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575485 c.138G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575486 p.Val47Ile missense_variant 0.92 ethionamide
isoniazid
mshA 575492 p.Leu49Val missense_variant 0.93 ethionamide
isoniazid
mshA 575495 c.148C>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575503 c.156G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575515 c.168G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575530 c.183C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575587 c.240C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575649 p.Val101Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575665 c.318G>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575683 c.336G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.99 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575786 p.Tyr147His missense_variant 0.99 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575860 c.513G>T synonymous_variant 0.99 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 0.98 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575923 c.576C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575980 c.633T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.93 ethionamide
isoniazid
ccsA 619531 c.-360T>G upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619534 c.-357G>A upstream_gene_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGG upstream_gene_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619541 c.-350_-348delCGCinsAG upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>C upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619564 c.-327C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619597 c.-294G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-255delTCCinsAGA upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619646 c.-245_-243delGTCinsAT upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619658 c.-233A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>T upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619923 c.33C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619926 c.36C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619932 c.42C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619953 c.63C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619962 c.72G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619968 c.78G>C synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620148 c.258G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620157 c.267G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620196 c.306C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Val missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.99 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620647 p.Glu253Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620691 c.801G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656052 c.1419A>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656064 c.1407C>G synonymous_variant 1.0 ethionamide
Rv0565c 656067 c.1404C>T synonymous_variant 1.0 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656085 c.1386A>G synonymous_variant 1.0 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 1.0 ethionamide
Rv0565c 656097 c.1374G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656112 c.1359C>G synonymous_variant 1.0 ethionamide
Rv0565c 656129 p.Tyr448His missense_variant 1.0 ethionamide
Rv0565c 656131 p.Pro447Leu missense_variant 1.0 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 1.0 ethionamide
Rv0565c 656149 p.Gly441Asn missense_variant 1.0 ethionamide
Rv0565c 656168 p.Ser435Ala missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656175 c.1296G>A synonymous_variant 1.0 ethionamide
Rv0565c 656179 p.Asp431Ala missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656184 c.1287G>C synonymous_variant 1.0 ethionamide
Rv0565c 656189 p.Glu428Gln missense_variant 1.0 ethionamide
Rv0565c 656190 c.1281C>T synonymous_variant 1.0 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.92 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.95 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.96 ethionamide
Rv0565c 656301 c.1170C>T synonymous_variant 0.96 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.96 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.97 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656370 c.1101T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656375 p.Asp366Asn missense_variant 1.0 ethionamide
Rv0565c 656379 c.1092G>A synonymous_variant 1.0 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 1.0 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 1.0 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.98 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.98 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.96 ethionamide
Rv0565c 656448 c.1021_1023delATTinsGC frameshift_variant&missense_variant 0.94 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.94 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.94 ethionamide
Rv0565c 656466 c.1005G>C synonymous_variant 0.93 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.93 ethionamide
Rv0565c 656472 c.999C>G synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656478 c.993C>G synonymous_variant 0.93 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 0.93 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.93 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656511 c.960T>C synonymous_variant 0.92 ethionamide Not assoc w R - Interim
Rv0565c 656514 c.957C>T synonymous_variant 0.92 ethionamide
Rv0565c 656538 c.931_933delAGCinsTCG synonymous_variant 0.86 ethionamide
Rv0565c 656541 c.930C>G synonymous_variant 0.86 ethionamide
Rv0565c 656547 c.924C>G synonymous_variant 0.86 ethionamide
Rv0565c 656551 p.Asn307Thr missense_variant 0.86 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 0.88 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 0.88 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 0.88 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 0.87 ethionamide
Rv0565c 656604 c.867G>A synonymous_variant 0.89 ethionamide
Rv0565c 656611 p.Thr287Lys missense_variant 0.8 ethionamide
Rv0565c 656935 p.Thr179Ser missense_variant 0.91 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.94 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 0.94 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 0.94 ethionamide
Rv0565c 656964 c.507C>G synonymous_variant 0.95 ethionamide
Rv0565c 656973 c.498A>C synonymous_variant 0.95 ethionamide
Rv0565c 656976 c.493_495delGCGinsAC frameshift_variant&missense_variant 0.95 ethionamide Uncertain significance
Rv0565c 656984 p.Gly163Arg missense_variant 1.0 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656997 c.474C>A synonymous_variant 1.0 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657034 p.Tyr146Phe missense_variant 1.0 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657330 c.141C>G synonymous_variant 1.0 ethionamide
Rv0565c 657340 p.Ala44Glu missense_variant 1.0 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 1.0 ethionamide
Rv0565c 657359 p.Thr38Ala missense_variant 1.0 ethionamide
Rv0565c 657367 p.Leu35Thr missense_variant 1.0 ethionamide
Rv0565c 657369 p.Gln34His missense_variant 1.0 ethionamide
Rv0565c 657381 c.90A>G synonymous_variant 1.0 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 1.0 ethionamide
Rv0565c 657396 c.75C>G synonymous_variant 1.0 ethionamide
Rv0565c 657581 c.-111G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657626 c.-156C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657656 c.-186C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-262G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731708 c.-222G>C upstream_gene_variant 0.9 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.9 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.92 isoniazid
hadA 731732 c.-198G>C upstream_gene_variant 0.97 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.98 isoniazid
hadA 731748 c.-182T>C upstream_gene_variant 0.98 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.99 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.98 isoniazid
hadA 731817 c.-113C>A upstream_gene_variant 0.98 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.97 isoniazid
hadA 731846 c.-84C>T upstream_gene_variant 0.97 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.97 isoniazid
hadA 732094 c.165T>C synonymous_variant 1.0 isoniazid
hadA 732098 c.169T>C synonymous_variant 1.0 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732126 p.Lys66Arg missense_variant 1.0 isoniazid
hadA 732134 p.Ala69Thr missense_variant 1.0 isoniazid Uncertain significance
hadA 732146 c.217_219delAAGinsGA frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732149 c.220_222delCATinsTC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732164 p.Thr79Val missense_variant 1.0 isoniazid
hadA 732168 p.Ala80Glu missense_variant 1.0 isoniazid
hadA 732172 p.Glu81Asp missense_variant 1.0 isoniazid
hadA 732190 c.261A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732196 c.267A>G synonymous_variant 1.0 isoniazid
hadA 732207 p.Phe93Tyr missense_variant 1.0 isoniazid
hadA 732209 p.Glu94Lys missense_variant 1.0 isoniazid
hadA 732214 c.285A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732226 c.297G>C synonymous_variant 1.0 isoniazid
hadA 732247 c.318C>T synonymous_variant 1.0 isoniazid
hadA 732259 c.330T>C synonymous_variant 1.0 isoniazid
hadA 732265 c.336G>C synonymous_variant 1.0 isoniazid
hadA 732268 c.339T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732269 p.Glu114Lys missense_variant 1.0 isoniazid
hadA 732272 p.Ala115Thr missense_variant 1.0 isoniazid Uncertain significance
hadA 732287 c.358_360delATCinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732290 p.Ile121Val missense_variant 1.0 isoniazid
hadA 732300 p.Lys124Arg missense_variant 1.0 isoniazid
hadA 732310 c.381C>T synonymous_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 1.0 isoniazid
hadA 732319 p.Glu130Asp missense_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.96 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.98 isoniazid
hadA 732355 c.426G>C synonymous_variant 0.98 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.98 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.97 isoniazid
hadA 732391 c.462T>G synonymous_variant 0.98 isoniazid
hadA 732392 p.Asp155His missense_variant 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Ile missense_variant 1.0 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734093 c.-161A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 1.0 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 1.0 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 1.0 rifampicin
nusG 734170 c.-83_-81delCGC upstream_gene_variant 1.0 rifampicin
nusG 734177 c.-77_-76insCTC upstream_gene_variant 1.0 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734204 c.-50G>C upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734222 c.-31_-27delGGCTC upstream_gene_variant 1.0 rifampicin
nusG 734229 c.-25A>C upstream_gene_variant 1.0 rifampicin
nusG 734234 c.-20G>T upstream_gene_variant 1.0 rifampicin
nusG 734262 c.9C>G synonymous_variant 1.0 rifampicin
nusG 734352 c.99T>C synonymous_variant 1.0 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734376 c.123G>A synonymous_variant 1.0 rifampicin
nusG 734388 c.135G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734409 c.156T>G synonymous_variant 0.98 rifampicin
nusG 734418 c.165C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734505 c.252G>A synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.97 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.96 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.94 rifampicin
nusG 734614 p.Ala121Ser missense_variant 0.94 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.91 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.94 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734682 c.429C>G synonymous_variant 0.94 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734712 c.459G>C synonymous_variant 1.0 rifampicin
nusG 734714 p.Arg154Pro missense_variant 1.0 rifampicin Uncertain significance
nusG 734718 c.465G>C synonymous_variant 1.0 rifampicin
nusG 734722 p.Thr157Ser missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734733 c.480T>C synonymous_variant 1.0 rifampicin
nusG 734742 c.489T>C synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.97 rifampicin
nusG 734764 p.Ala171Thr missense_variant 0.98 rifampicin
nusG 734778 c.525G>C synonymous_variant 0.93 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.95 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.95 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.96 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.97 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.97 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.98 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.98 rifampicin
nusG 734877 c.624C>T synonymous_variant 0.99 rifampicin
nusG 734882 p.Ala210Gly missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734925 c.672C>T synonymous_variant 0.97 rifampicin
nusG 734931 c.678A>G synonymous_variant 0.97 rifampicin
nusG 734940 c.687G>A synonymous_variant 0.95 rifampicin
nusG 734943 c.690G>C synonymous_variant 0.94 rifampicin
nusG 734949 c.696T>C synonymous_variant 0.94 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.95 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>G synonymous_variant 1.0 rifampicin
rpoB 760124 c.318C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.96 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.96 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>A synonymous_variant 0.98 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.89 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.98 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.97 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.98 rifampicin
rpoB 760514 c.708C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.99 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.98 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.98 rifampicin Uncertain significance
rpoB 760568 c.762G>C synonymous_variant 0.98 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.99 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 0.97 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760674 c.868T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760683 c.877_879delTTGinsCC frameshift_variant&missense_variant 0.96 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760727 c.921C>T synonymous_variant 0.88 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.87 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.98 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 0.98 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.98 rifampicin
rpoB 761006 c.1200C>T synonymous_variant 0.98 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>G synonymous_variant 1.0 rifampicin
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.98 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 0.98 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.97 rifampicin
rpoB 761309 c.1503C>T synonymous_variant 0.97 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>A synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761437 p.Ala544Asp missense_variant 1.0 rifampicin
rpoB 761451 p.Val549Thr missense_variant 1.0 rifampicin
rpoB 761457 p.Pro551Ala missense_variant 1.0 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 1.0 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.98 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 1.0 rifampicin
rpoB 761843 c.2037C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 0.95 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.97 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.97 rifampicin
rpoB 761870 c.2064C>T synonymous_variant 0.97 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.97 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.97 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.98 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.98 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.98 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.98 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.99 rifampicin Uncertain significance
rpoB 762140 c.2334G>C synonymous_variant 0.99 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.99 rifampicin
rpoB 762146 c.2340G>A synonymous_variant 0.99 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.99 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.99 rifampicin
rpoB 762278 c.2472C>G synonymous_variant 0.97 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.98 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762335 c.2529C>A synonymous_variant 0.98 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762368 c.2562G>A synonymous_variant 0.97 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.97 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.95 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.95 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762425 c.2619C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.97 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762590 c.-780C>G upstream_gene_variant 1.0 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 1.0 rifampicin
rpoC 762605 c.-765T>C upstream_gene_variant 1.0 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 1.0 rifampicin
rpoB 762630 p.Ala942Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 762634 p.Ala943Gly missense_variant 1.0 rifampicin
rpoB 762638 p.Lys944Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 762641 c.-729G>A upstream_gene_variant 1.0 rifampicin
rpoC 762647 c.-723G>C upstream_gene_variant 1.0 rifampicin
rpoC 762656 c.-714C>G upstream_gene_variant 1.0 rifampicin
rpoB 762661 p.Arg952Lys missense_variant 1.0 rifampicin Uncertain significance
rpoB 762663 c.2857C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762669 c.2863_2865delGACinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762680 c.-690C>G upstream_gene_variant 1.0 rifampicin
rpoB 762683 p.Glu959Asp missense_variant 1.0 rifampicin
rpoB 762687 p.Gln961Glu missense_variant 1.0 rifampicin
rpoC 762701 c.-669T>C upstream_gene_variant 1.0 rifampicin
rpoC 762704 c.-666G>T upstream_gene_variant 1.0 rifampicin
rpoB 762725 c.2919C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762741 c.-629C>T upstream_gene_variant 0.97 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 0.97 rifampicin
rpoB 762759 p.Cys985Ala missense_variant 0.97 rifampicin
rpoC 762776 c.-594C>G upstream_gene_variant 0.93 rifampicin
rpoB 762781 p.Gly992Asp missense_variant 0.95 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 0.95 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.95 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.97 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762819 p.Phe1005Leu missense_variant 0.97 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.96 rifampicin
rpoB 762959 c.3153G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762971 c.3165G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.98 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763193 c.-177C>T upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763271 c.-99C>T upstream_gene_variant 1.0 rifampicin
rpoC 763274 c.-96G>C upstream_gene_variant 1.0 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.97 rifampicin
rpoC 763417 c.48C>G synonymous_variant 0.98 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.98 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.98 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763627 c.258G>A synonymous_variant 0.99 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>T synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763718 c.349C>T synonymous_variant 1.0 rifampicin
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763729 c.360G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763783 c.414G>C synonymous_variant 1.0 rifampicin
rpoC 763792 c.423G>A synonymous_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763825 c.456G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>A synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763870 c.501C>T synonymous_variant 0.98 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 c.507A>G synonymous_variant 0.98 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 0.98 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.98 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 0.97 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.97 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.96 rifampicin
rpoC 763949 c.580C>A synonymous_variant 0.97 rifampicin
rpoC 763978 c.609C>G synonymous_variant 0.98 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.99 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764159 c.790C>T synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 1.0 rifampicin
rpoC 764246 c.877_879delCTCinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.98 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.98 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.98 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.98 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764359 c.990C>T synonymous_variant 0.99 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.98 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764419 c.1050C>G synonymous_variant 0.98 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764449 c.1080G>C synonymous_variant 0.98 rifampicin
rpoC 764455 c.1086G>C synonymous_variant 0.98 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.98 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.98 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.98 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764932 c.1563C>G synonymous_variant 0.97 rifampicin
rpoC 764953 c.1584G>C synonymous_variant 0.97 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.93 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>G synonymous_variant 0.96 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>T synonymous_variant 0.95 rifampicin
rpoC 765055 c.1686C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.93 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.93 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 0.93 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765300 p.Val644Ala missense_variant 0.97 rifampicin Uncertain significance
rpoC 765305 p.Ile646Leu missense_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 c.1957_1959delCACinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765329 c.1960_1961delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765346 c.1977C>T synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765373 c.2004G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 1.0 rifampicin
rpoC 765409 c.2040T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765413 p.Pro682Ala missense_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.99 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.96 rifampicin
rpoC 765535 c.2166C>T synonymous_variant 0.97 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.97 rifampicin
rpoC 765550 c.2181C>T synonymous_variant 0.97 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.97 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.97 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.99 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765673 c.2304C>T synonymous_variant 0.99 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 0.96 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.99 rifampicin Uncertain significance
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.99 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.99 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>G synonymous_variant 1.0 rifampicin
rpoC 765850 c.2481G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.97 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.99 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 0.97 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>A synonymous_variant 0.98 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766079 c.2710_2712delCGTinsAC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.95 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.98 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.97 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 0.96 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766150 c.2781C>G synonymous_variant 1.0 rifampicin
rpoC 766163 p.Glu932Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 766167 p.Ala933Asp missense_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766291 c.2922G>C synonymous_variant 1.0 rifampicin
rpoC 766306 c.2937C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>T synonymous_variant 0.97 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.97 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.98 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.98 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.98 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.98 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.99 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>A synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.97 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.97 rifampicin
rpoC 766540 c.3171C>T synonymous_variant 0.94 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.96 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.95 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.96 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 0.95 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.95 rifampicin
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.97 rifampicin
rpoC 766645 p.Glu1092Asp missense_variant 0.95 rifampicin Not assoc w R
rpoC 766657 c.3288A>G synonymous_variant 0.96 rifampicin
rpoC 766658 c.3289_3291delCGGinsGA frameshift_variant&missense_variant 0.94 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.96 rifampicin
rpoC 766669 c.3300C>A synonymous_variant 0.94 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.96 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.94 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.98 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.98 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 0.97 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.98 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.98 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.95 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766923 p.Glu1185Gly missense_variant 0.95 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.98 rifampicin
rpoC 766945 c.3576A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.99 rifampicin
rpoC 767032 c.3663G>C synonymous_variant 0.98 rifampicin
rpoC 767035 c.3666G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.99 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
mmpL5 775847 c.2634G>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.97 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775913 c.2568C>G synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 775949 c.2532G>T synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.86 clofazimine
bedaquiline
mmpL5 775973 c.2506_2508delTTGinsCC frameshift_variant&missense_variant 0.85 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775981 p.Leu834Met missense_variant 0.97 clofazimine
bedaquiline
mmpL5 775994 c.2487C>T synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775997 c.2484T>G synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776003 c.2476_2478delATCinsCG frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776039 c.2442C>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 776665 p.Thr606Ala missense_variant 0.73 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776672 c.1809G>T synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 776678 c.1803G>T synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776693 c.1788C>G synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776711 c.1770C>T synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776735 c.1746C>T synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 776744 c.1737C>G synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.91 clofazimine
bedaquiline
mmpL5 777182 c.1299C>G synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777191 c.1290C>A synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777209 c.1272C>T synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777214 p.Ala423Thr missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777225 p.Asn419Thr missense_variant 0.88 clofazimine
bedaquiline
mmpL5 777245 c.1236G>C synonymous_variant 0.91 clofazimine
bedaquiline
mmpL5 777251 c.1230C>A synonymous_variant 0.9 clofazimine
bedaquiline
rpsL 781128 c.-432C>G upstream_gene_variant 0.95 streptomycin
rpsL 781134 c.-426T>G upstream_gene_variant 0.96 streptomycin
rpsL 781138 c.-422C>G upstream_gene_variant 0.96 streptomycin
rpsL 781143 c.-417T>G upstream_gene_variant 0.97 streptomycin
rpsL 781161 c.-399G>A upstream_gene_variant 0.97 streptomycin
rpsL 781164 c.-396T>C upstream_gene_variant 0.97 streptomycin
rpsL 781170 c.-390G>C upstream_gene_variant 0.97 streptomycin
rpsL 781173 c.-387A>G upstream_gene_variant 0.97 streptomycin
rpsL 781179 c.-381T>C upstream_gene_variant 0.98 streptomycin
rpsL 781182 c.-378G>C upstream_gene_variant 0.98 streptomycin
rpsL 781185 c.-375T>C upstream_gene_variant 0.98 streptomycin
rpsL 781206 c.-354C>T upstream_gene_variant 1.0 streptomycin
rpsL 781209 c.-351C>G upstream_gene_variant 1.0 streptomycin
rpsL 781224 c.-336T>C upstream_gene_variant 1.0 streptomycin
rpsL 781227 c.-333C>G upstream_gene_variant 1.0 streptomycin
rpsL 781234 c.-326G>C upstream_gene_variant 1.0 streptomycin
rpsL 781240 c.-320A>T upstream_gene_variant 1.0 streptomycin
rpsL 781257 c.-303G>T upstream_gene_variant 1.0 streptomycin
rpsL 781260 c.-300G>C upstream_gene_variant 1.0 streptomycin
rpsL 781264 c.-296G>A upstream_gene_variant 1.0 streptomycin
rpsL 781270 c.-290A>C upstream_gene_variant 1.0 streptomycin
rpsL 781391 c.-169_-168insCGG upstream_gene_variant 0.8 streptomycin
rpsL 781571 c.12C>T synonymous_variant 0.95 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.99 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.96 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.97 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.96 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.97 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.96 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.97 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.97 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.95 streptomycin
rpsL 781817 c.258G>A synonymous_variant 0.96 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.96 streptomycin
rpsL 781826 c.267C>T synonymous_variant 0.95 streptomycin Not assoc w R - Interim
rpsL 781832 c.273T>C synonymous_variant 0.96 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.97 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.96 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.96 streptomycin
rpsL 781871 c.312G>A synonymous_variant 0.96 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.96 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.98 streptomycin
rpsL 781910 c.351C>T synonymous_variant 0.99 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.99 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.99 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.99 streptomycin
rplC 800474 c.-335_-334insG upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 0.97 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.98 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.96 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 0.98 linezolid
rplC 800555 c.-254C>A upstream_gene_variant 0.97 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.99 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.99 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.99 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.98 linezolid
rplC 800672 c.-137G>A upstream_gene_variant 0.98 linezolid
rplC 800690 c.-119C>G upstream_gene_variant 0.98 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.98 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.99 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.96 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.98 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 0.96 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 0.93 linezolid
rplC 800808 c.-1delAinsTC upstream_gene_variant 0.93 linezolid
rplC 800815 c.7C>A synonymous_variant 0.92 linezolid
rplC 800820 c.12G>A synonymous_variant 0.93 linezolid
rplC 800829 c.21C>G synonymous_variant 0.96 linezolid
rplC 800844 c.36T>C synonymous_variant 0.95 linezolid
rplC 800856 c.48A>G synonymous_variant 0.97 linezolid
rplC 800865 c.57A>G synonymous_variant 0.96 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.95 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.95 linezolid
rplC 800877 c.69A>C synonymous_variant 0.95 linezolid
rplC 800880 c.72A>C synonymous_variant 0.93 linezolid
rplC 800901 c.93C>G synonymous_variant 0.98 linezolid
rplC 800904 c.96G>C synonymous_variant 0.89 linezolid
rplC 800916 c.108A>G synonymous_variant 0.96 linezolid
rplC 800934 c.126C>G synonymous_variant 0.96 linezolid
rplC 800937 c.129A>G synonymous_variant 0.96 linezolid
rplC 800946 c.138T>C synonymous_variant 0.95 linezolid
rplC 800949 c.141T>C synonymous_variant 0.94 linezolid
rplC 800967 c.159C>G synonymous_variant 0.94 linezolid
rplC 800970 c.162T>C synonymous_variant 0.94 linezolid Not assoc w R - Interim
rplC 800973 c.165C>G synonymous_variant 0.94 linezolid
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 0.92 linezolid
rplC 801135 c.327C>T synonymous_variant 0.92 linezolid
rplC 801136 p.Ser110Ala missense_variant 1.0 linezolid
rplC 801141 c.333C>T synonymous_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801159 c.351C>G synonymous_variant 1.0 linezolid
rplC 801162 c.354C>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801246 c.438C>G synonymous_variant 0.98 linezolid
rplC 801249 c.441T>G synonymous_variant 0.98 linezolid
rplC 801255 c.447C>T synonymous_variant 0.98 linezolid
rplC 801270 c.462T>C synonymous_variant 0.97 linezolid
rplC 801276 c.468G>T synonymous_variant 0.97 linezolid
rplC 801285 c.477G>C synonymous_variant 0.97 linezolid
rplC 801288 c.480G>C synonymous_variant 0.97 linezolid
rplC 801303 c.495G>T synonymous_variant 0.98 linezolid
rplC 801312 c.504G>C synonymous_variant 0.98 linezolid
rplC 801333 c.525G>A synonymous_variant 0.98 linezolid
rplC 801339 c.531T>G synonymous_variant 0.97 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.97 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.98 linezolid
rplC 801396 c.588T>C synonymous_variant 0.97 linezolid
rplC 801400 c.592_594delGTTinsAC frameshift_variant&missense_variant 0.96 linezolid
rplC 801405 c.597T>C synonymous_variant 0.96 linezolid
rplC 801423 c.615G>C synonymous_variant 0.95 linezolid
rplC 801426 c.618C>G synonymous_variant 0.94 linezolid
rplC 801438 c.630T>C synonymous_variant 0.88 linezolid
fbiC 1303242 c.312T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303251 c.321C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303257 c.327C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303263 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303268 p.Lys113Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303272 c.342A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303281 c.351A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303284 c.354T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303285 p.Ser119Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303288 p.Ser120Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303292 p.Thr121Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303296 c.366T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303302 c.372A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303440 c.510G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303542 c.612C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303713 c.783C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303722 c.792C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303782 c.852C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303812 c.882C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303815 c.885C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303827 c.897A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303844 p.Ala305Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303896 c.966G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303903 c.973C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303908 c.978C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303938 c.1008C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304016 c.1086C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304104 c.1174C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304154 c.1224G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304165 p.Gly412Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304199 c.1269C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304220 c.1290G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304223 c.1293G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304255 p.Ala442Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304261 p.Trp444Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304415 c.1485G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304424 c.1494C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304436 c.1506G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304439 c.1509G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304444 p.Ala505Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304484 c.1554C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304487 c.1557C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304547 c.1617C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304577 c.1647C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304589 c.1659C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304802 c.1872G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304805 c.1875G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304889 c.1959G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305106 c.2176C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305114 p.Asp728Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305318 c.2388C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305411 c.2481C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305414 c.2484G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305420 c.2490C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305426 c.2496G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305431 p.Val834Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305441 c.2511C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364661 c.249C>G synonymous_variant 0.85 pyrazinamide
sigE 1364667 c.255T>C synonymous_variant 0.92 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.93 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 0.93 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.92 pyrazinamide
sigE 1364694 c.282G>C synonymous_variant 0.92 pyrazinamide
sigE 1364697 c.285G>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364718 c.306C>G synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364910 c.498G>C synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 c.510G>A synonymous_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 1.0 pyrazinamide
sigE 1364950 c.538_540delGCAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1365000 c.588G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
embR 1416307 c.1041C>G synonymous_variant 1.0 ethambutol
embR 1416313 c.1035A>G synonymous_variant 1.0 ethambutol
embR 1416327 p.Ile341Leu missense_variant 1.0 ethambutol
embR 1416330 p.Val340Ile missense_variant 1.0 ethambutol
embR 1416335 p.Asn338Ser missense_variant 1.0 ethambutol
embR 1416358 c.990C>A synonymous_variant 1.0 ethambutol
embR 1416367 c.981C>G synonymous_variant 1.0 ethambutol
embR 1416637 c.711C>T synonymous_variant 1.0 ethambutol
embR 1416643 c.705G>C synonymous_variant 1.0 ethambutol
embR 1416646 c.702A>G synonymous_variant 1.0 ethambutol
embR 1416652 c.696G>A synonymous_variant 1.0 ethambutol
embR 1416671 p.Gly226Ala missense_variant 1.0 ethambutol
embR 1416675 c.673C>T synonymous_variant 1.0 ethambutol
embR 1416679 c.669T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embR 1416688 c.660G>C synonymous_variant 1.0 ethambutol
embR 1416696 p.Ser218Thr missense_variant 1.0 ethambutol
embR 1416721 c.625_627delACAinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embR 1416731 p.Pro206Gln missense_variant 1.0 ethambutol
embR 1416736 c.612G>C synonymous_variant 1.0 ethambutol
embR 1416752 p.Phe199Ala missense_variant 1.0 ethambutol
embR 1416754 c.594A>C synonymous_variant 1.0 ethambutol
embR 1416760 c.588T>G synonymous_variant 1.0 ethambutol
embR 1417042 c.306G>A synonymous_variant 1.0 ethambutol
atpE 1460804 c.-241T>C upstream_gene_variant 0.95 bedaquiline
atpE 1460807 c.-238C>T upstream_gene_variant 0.97 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.98 bedaquiline
atpE 1460840 c.-205A>C upstream_gene_variant 0.98 bedaquiline
atpE 1460850 c.-195_-193delCTCinsAG upstream_gene_variant 0.97 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.93 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.97 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.97 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1461068 c.24C>T synonymous_variant 1.0 bedaquiline
atpE 1461071 c.27C>T synonymous_variant 1.0 bedaquiline
atpE 1461087 c.43_45delCTGinsAC frameshift_variant&missense_variant 0.93 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 0.93 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.93 bedaquiline
atpE 1461107 c.63C>A synonymous_variant 0.92 bedaquiline
atpE 1461113 c.69C>A synonymous_variant 0.94 bedaquiline
atpE 1461122 c.78C>T synonymous_variant 0.95 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.96 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.95 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.95 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.96 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.96 bedaquiline Uncertain significance
atpE 1461173 c.129C>G synonymous_variant 0.97 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.95 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
atpE 1461261 c.217C>T synonymous_variant 1.0 bedaquiline
atpE 1461275 c.231T>C synonymous_variant 0.95 bedaquiline
atpE 1461278 c.234A>T synonymous_variant 0.9 bedaquiline
atpE 1461286 p.Lys81Thr missense_variant 0.82 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471675 n.-171G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471684 n.-162A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471685 n.-161A>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471687 n.-159C>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472044 n.199G>A non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473684 n.27G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473943 n.286G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474029 n.372G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474060 n.403G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474664 n.1007G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474997 n.1340A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475019 n.1362T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475239 n.1582A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475622 n.1965G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476044 n.2387T>A