TB-Profiler result

Run: ERR212121
Summary

Run ID: ERR212121

Sample name:

Date: 2024-04-16T09:22:57.398989

Number of reads: 1064752

Percentage reads mapped: 22.9

Median coverage: 23.0

Strain: lineage4.9;lineage6.3

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.09
lineage4.1.4 Euro-American None 0.07
lineage6.3 West-Africa 2 RD702 0.08
La1.2.BCG M.bovis None 0.09
lineage4.3.2.1 Euro-American (LAM) RD761 0.13
lineage3.1.2.2 East-African-Indian RD750 0.28
lineage6.1.3 West-Africa 2 RD702 0.14
lineage4.9 Euro-American (H37Rv-like) None 0.66
La1.8.2 M.bovis None 0.09
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.Ala388Gly Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.4_6delGCAinsCT Assoc w R
kanamycin
cycloserine
ethionamide ethA c.1129_1131delATCinsCG Assoc w R
c.571_573delGTGinsAT Assoc w R
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.973_975delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.691_693delTACinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1207_1209delGCGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1549_1551delCTTinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1567_1569delCCTinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1945_1947delATTinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD c.127_129delCTCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.358_360delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.388_390delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.220_222delATTinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.244_246delGCGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491755 c.973_975delCAGinsGA frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303621 c.691_693delTACinsCT frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304137 c.1207_1209delGCGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304479 c.1549_1551delCTTinsTG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304497 c.1567_1569delCCTinsGC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304875 c.1945_1947delATTinsGC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
tlyA 1917943 c.4_6delGCAinsCT frameshift_variant&missense_variant 1.0 capreomycin Assoc w R
katG 2155108 p.Ile335Thr missense_variant 0.88 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.88 isoniazid Assoc w R High-level resistance
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
fbiD 3339244 c.127_129delCTCinsTG frameshift_variant&missense_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD 3339475 c.358_360delTTAinsCG frameshift_variant&missense_variant 0.91 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD 3339505 c.388_390delTCGinsGC frameshift_variant&missense_variant 0.93 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987063 c.220_222delATTinsGG frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn 3987087 c.244_246delGCGinsTC frameshift_variant&missense_variant 0.98 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247676 p.Ala388Gly missense_variant 0.92 ethambutol Mutation from literature
ethA 4326343 c.1129_1131delATCinsCG frameshift_variant&missense_variant 0.69 ethionamide Assoc w R
ethA 4326901 c.571_573delGTGinsAT frameshift_variant&missense_variant 0.97 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 22 p.Gly8Thr missense_variant 1.0 isoniazid
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 138 c.138T>G synonymous_variant 1.0 isoniazid
dnaA 144 c.144C>G synonymous_variant 1.0 isoniazid
dnaA 150 c.150C>G synonymous_variant 1.0 isoniazid
dnaA 156 c.156G>A synonymous_variant 1.0 isoniazid
dnaA 159 c.159A>G synonymous_variant 1.0 isoniazid
dnaA 187 c.187_189delTTAinsCG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 192 c.192C>G synonymous_variant 1.0 isoniazid
dnaA 204 c.204C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 207 c.207T>C synonymous_variant 1.0 isoniazid
dnaA 213 c.213A>G synonymous_variant 1.0 isoniazid
dnaA 219 c.219A>G synonymous_variant 1.0 isoniazid
dnaA 510 c.510T>C synonymous_variant 0.93 isoniazid
dnaA 522 c.522T>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 0.92 isoniazid
dnaA 528 c.528G>C synonymous_variant 0.93 isoniazid
dnaA 534 c.534T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 540 c.540C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 564 c.564C>G synonymous_variant 0.98 isoniazid
dnaA 570 c.570C>A synonymous_variant 0.98 isoniazid
dnaA 571 c.571_573delTTGinsCC frameshift_variant&missense_variant 0.98 isoniazid Uncertain significance
dnaA 576 c.576G>C synonymous_variant 0.98 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 0.98 isoniazid
dnaA 600 c.600T>G synonymous_variant 0.98 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.98 isoniazid
dnaA 618 c.618C>A synonymous_variant 0.97 isoniazid
dnaA 627 c.627G>A synonymous_variant 1.0 isoniazid
dnaA 633 c.633T>C synonymous_variant 0.94 isoniazid
dnaA 648 c.648C>T synonymous_variant 0.94 isoniazid
dnaA 652 c.652_654delCTAinsTG frameshift_variant&stop_gained 0.94 isoniazid Uncertain significance
dnaA 663 c.663A>C synonymous_variant 0.94 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.94 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 693 c.693A>G synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.89 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.89 isoniazid
dnaA 717 c.717C>T synonymous_variant 0.94 isoniazid
dnaA 723 c.723A>G synonymous_variant 0.95 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 0.89 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.94 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.95 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.96 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 798 c.798C>T synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.97 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.94 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.97 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.94 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.97 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.97 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 0.97 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.97 isoniazid
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.97 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.96 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.96 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.96 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.97 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.95 isoniazid
dnaA 957 c.957A>G synonymous_variant 0.94 isoniazid
dnaA 960 c.960C>G synonymous_variant 0.91 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.94 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.92 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.89 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 996 c.996A>G synonymous_variant 0.96 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 0.96 isoniazid
dnaA 1050 c.1050G>T synonymous_variant 0.96 isoniazid
dnaA 1059 c.1059C>G synonymous_variant 0.98 isoniazid
dnaA 1065 c.1065C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.97 isoniazid
dnaA 1071 c.1071C>A synonymous_variant 0.99 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.97 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.99 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.99 isoniazid
dnaA 1125 c.1125G>T synonymous_variant 0.99 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 0.97 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.99 isoniazid
dnaA 1146 c.1146C>T synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.99 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.99 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.99 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.98 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.98 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.97 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.97 isoniazid
dnaA 1239 c.1239G>C synonymous_variant 0.97 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.98 isoniazid
dnaA 1281 c.1281C>A synonymous_variant 0.98 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.98 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.96 isoniazid
dnaA 1311 c.1311C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1317 c.1317A>G synonymous_variant 0.99 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 1.0 isoniazid
dnaA 1350 c.1350G>A synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>C synonymous_variant 0.98 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.98 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.98 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.96 isoniazid
dnaA 1404 c.1404T>G synonymous_variant 0.97 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.97 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.97 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.97 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.97 isoniazid
dnaA 1461 c.1461C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1464 c.1464T>C synonymous_variant 0.97 isoniazid
dnaA 1470 c.1470C>G synonymous_variant 1.0 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1482 c.1482C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1485 c.1485A>G synonymous_variant 1.0 isoniazid
dnaA 1497 c.1497T>G synonymous_variant 1.0 isoniazid
dnaA 1512 c.1512C>G synonymous_variant 1.0 isoniazid
gyrB 5858 p.Asn207His missense_variant 0.94 levofloxacin
moxifloxacin
gyrB 5866 c.627C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5869 c.630C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5880 p.Thr214Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 5882 c.643_645delCAAinsAC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5887 p.Asp216Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 5893 c.654C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5905 c.666G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6047 p.Ala270Pro missense_variant 0.82 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6056 c.817_818delAGinsTC synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6076 c.837C>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6078 p.Gly280Asp missense_variant 0.8 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6142 c.903G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6145 c.906C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6196 c.957C>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.95 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6349 c.-953G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6577 c.-725T>A upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6865 c.-437G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6886 c.-416C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6887 c.-415C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6892 c.-410C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7344 p.Ile15Val missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7349 c.48A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7427 c.126G>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7466 c.165G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7688 c.387C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7808 c.507G>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 c.618G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8183 c.882C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8216 c.915G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8369 c.1068G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8435 c.1134C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8576 c.1275C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 p.Glu429Asp missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8738 c.1437G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8836 p.Ala512Val missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8885 c.1584C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8921 c.1620C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8924 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8978 c.1677C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9056 c.1755C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCT frameshift_variant&synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.98 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Glu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9184 p.Arg628Gln missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9263 c.1962C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9281 c.1980C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.94 isoniazid
Rv0010c 13884 c.-326A>G upstream_gene_variant 0.95 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.96 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.96 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.97 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.97 isoniazid
fgd1 490777 c.-6G>T upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490781 c.-2T>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490782 c.-1G>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490803 c.21T>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490899 c.117C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491058 c.276C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491112 c.330G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491532 c.750G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491623 p.Ala281Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491712 c.930T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491721 c.939A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491727 c.945T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491739 c.957G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
fgd1 491758 p.Ser326Lys missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491769 c.987A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
mshA 574604 c.-744C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574607 c.-741G>T upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574616 c.-732G>T upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574631 c.-717C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574640 c.-708G>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.98 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.98 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574698 c.-650G>A upstream_gene_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574712 c.-636A>G upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575485 c.138G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575486 p.Val47Ile missense_variant 0.92 ethionamide
isoniazid
mshA 575492 p.Leu49Val missense_variant 0.93 ethionamide
isoniazid
mshA 575495 c.148C>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575503 c.156G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575515 c.168G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575530 c.183C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575587 c.240C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575649 p.Val101Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575665 c.318G>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575683 c.336G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.99 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575786 p.Tyr147His missense_variant 0.99 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575860 c.513G>T synonymous_variant 0.99 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 0.98 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575923 c.576C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575980 c.633T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.93 ethionamide
isoniazid
ccsA 619531 c.-360T>G upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619534 c.-357G>A upstream_gene_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGG upstream_gene_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619541 c.-350_-348delCGCinsAG upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>C upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619564 c.-327C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619597 c.-294G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-255delTCCinsAGA upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619646 c.-245_-243delGTCinsAT upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619658 c.-233A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>T upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619923 c.33C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619926 c.36C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619932 c.42C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619953 c.63C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619962 c.72G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619968 c.78G>C synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620148 c.258G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620157 c.267G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620184 c.294C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620196 c.306C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Val missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.99 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620647 p.Glu253Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620691 c.801G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656052 c.1419A>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656064 c.1407C>G synonymous_variant 1.0 ethionamide
Rv0565c 656067 c.1404C>T synonymous_variant 1.0 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656085 c.1386A>G synonymous_variant 1.0 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 1.0 ethionamide
Rv0565c 656097 c.1374G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656112 c.1359C>G synonymous_variant 1.0 ethionamide
Rv0565c 656129 p.Tyr448His missense_variant 1.0 ethionamide
Rv0565c 656131 p.Pro447Leu missense_variant 1.0 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 1.0 ethionamide
Rv0565c 656149 p.Gly441Asn missense_variant 1.0 ethionamide
Rv0565c 656168 p.Ser435Ala missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656175 c.1296G>A synonymous_variant 1.0 ethionamide
Rv0565c 656179 p.Asp431Ala missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656184 c.1287G>C synonymous_variant 1.0 ethionamide
Rv0565c 656189 p.Glu428Gln missense_variant 1.0 ethionamide
Rv0565c 656190 c.1281C>T synonymous_variant 1.0 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.92 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.95 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.96 ethionamide
Rv0565c 656301 c.1170C>T synonymous_variant 0.96 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.96 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.97 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656370 c.1101T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656375 p.Asp366Asn missense_variant 1.0 ethionamide
Rv0565c 656379 c.1092G>A synonymous_variant 1.0 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 1.0 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 1.0 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.98 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.98 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.96 ethionamide
Rv0565c 656448 c.1021_1023delATTinsGC frameshift_variant&missense_variant 0.94 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.94 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.94 ethionamide
Rv0565c 656466 c.1005G>C synonymous_variant 0.93 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.93 ethionamide
Rv0565c 656472 c.999C>G synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656478 c.993C>G synonymous_variant 0.93 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 0.93 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.93 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656511 c.960T>C synonymous_variant 0.92 ethionamide Not assoc w R - Interim
Rv0565c 656514 c.957C>T synonymous_variant 0.92 ethionamide
Rv0565c 656538 c.931_933delAGCinsTCG synonymous_variant 0.86 ethionamide
Rv0565c 656541 c.930C>G synonymous_variant 0.86 ethionamide
Rv0565c 656547 c.924C>G synonymous_variant 0.86 ethionamide
Rv0565c 656551 p.Asn307Thr missense_variant 0.86 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 0.88 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 0.88 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 0.88 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 0.87 ethionamide
Rv0565c 656604 c.867G>A synonymous_variant 0.89 ethionamide
Rv0565c 656611 p.Thr287Lys missense_variant 0.8 ethionamide
Rv0565c 656935 p.Thr179Ser missense_variant 0.91 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.94 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 0.94 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 0.94 ethionamide
Rv0565c 656964 c.507C>G synonymous_variant 0.95 ethionamide
Rv0565c 656973 c.498A>C synonymous_variant 0.95 ethionamide
Rv0565c 656976 c.493_495delGCGinsAC frameshift_variant&missense_variant 0.95 ethionamide Uncertain significance
Rv0565c 656984 p.Gly163Arg missense_variant 1.0 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656997 c.474C>A synonymous_variant 1.0 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657034 p.Tyr146Phe missense_variant 1.0 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657330 c.141C>G synonymous_variant 1.0 ethionamide
Rv0565c 657340 p.Ala44Glu missense_variant 1.0 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 1.0 ethionamide
Rv0565c 657359 p.Thr38Ala missense_variant 1.0 ethionamide
Rv0565c 657367 p.Leu35Thr missense_variant 1.0 ethionamide
Rv0565c 657369 p.Gln34His missense_variant 1.0 ethionamide
Rv0565c 657381 c.90A>G synonymous_variant 1.0 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 1.0 ethionamide
Rv0565c 657396 c.75C>G synonymous_variant 1.0 ethionamide
Rv0565c 657581 c.-111G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657626 c.-156C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657656 c.-186C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-262G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731708 c.-222G>C upstream_gene_variant 0.9 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.9 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.92 isoniazid
hadA 731732 c.-198G>C upstream_gene_variant 0.97 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.98 isoniazid
hadA 731748 c.-182T>C upstream_gene_variant 0.98 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.99 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.98 isoniazid
hadA 731817 c.-113C>A upstream_gene_variant 0.98 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.97 isoniazid
hadA 731846 c.-84C>T upstream_gene_variant 0.97 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.97 isoniazid
hadA 732094 c.165T>C synonymous_variant 1.0 isoniazid
hadA 732098 c.169T>C synonymous_variant 1.0 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732126 p.Lys66Arg missense_variant 1.0 isoniazid
hadA 732134 p.Ala69Thr missense_variant 1.0 isoniazid Uncertain significance
hadA 732146 c.217_219delAAGinsGA frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732149 c.220_222delCATinsTC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732164 p.Thr79Val missense_variant 1.0 isoniazid
hadA 732168 p.Ala80Glu missense_variant 1.0 isoniazid
hadA 732172 p.Glu81Asp missense_variant 1.0 isoniazid
hadA 732190 c.261A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732196 c.267A>G synonymous_variant 1.0 isoniazid
hadA 732207 p.Phe93Tyr missense_variant 1.0 isoniazid
hadA 732209 p.Glu94Lys missense_variant 1.0 isoniazid
hadA 732214 c.285A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732226 c.297G>C synonymous_variant 1.0 isoniazid
hadA 732247 c.318C>T synonymous_variant 1.0 isoniazid
hadA 732259 c.330T>C synonymous_variant 1.0 isoniazid
hadA 732265 c.336G>C synonymous_variant 1.0 isoniazid
hadA 732268 c.339T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732269 p.Glu114Lys missense_variant 1.0 isoniazid
hadA 732272 p.Ala115Thr missense_variant 1.0 isoniazid Uncertain significance
hadA 732287 c.358_360delATCinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732290 p.Ile121Val missense_variant 1.0 isoniazid
hadA 732300 p.Lys124Arg missense_variant 1.0 isoniazid
hadA 732310 c.381C>T synonymous_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 1.0 isoniazid
hadA 732319 p.Glu130Asp missense_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.96 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.98 isoniazid
hadA 732355 c.426G>C synonymous_variant 0.98 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.98 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.97 isoniazid
hadA 732391 c.462T>G synonymous_variant 0.98 isoniazid
hadA 732392 p.Asp155His missense_variant 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Ile missense_variant 1.0 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734093 c.-161A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 1.0 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 1.0 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 1.0 rifampicin
nusG 734170 c.-83_-81delCGC upstream_gene_variant 1.0 rifampicin
nusG 734177 c.-77_-76insCTC upstream_gene_variant 1.0 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734204 c.-50G>C upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734222 c.-31_-27delGGCTC upstream_gene_variant 1.0 rifampicin
nusG 734229 c.-25A>C upstream_gene_variant 1.0 rifampicin
nusG 734234 c.-20G>T upstream_gene_variant 1.0 rifampicin
nusG 734262 c.9C>G synonymous_variant 1.0 rifampicin
nusG 734352 c.99T>C synonymous_variant 1.0 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734376 c.123G>A synonymous_variant 1.0 rifampicin
nusG 734388 c.135G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734409 c.156T>G synonymous_variant 0.98 rifampicin
nusG 734418 c.165C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734505 c.252G>A synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.97 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.96 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.94 rifampicin
nusG 734614 p.Ala121Ser missense_variant 0.94 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.91 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.94 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734682 c.429C>G synonymous_variant 0.94 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734712 c.459G>C synonymous_variant 1.0 rifampicin
nusG 734714 p.Arg154Pro missense_variant 1.0 rifampicin Uncertain significance
nusG 734718 c.465G>C synonymous_variant 1.0 rifampicin
nusG 734722 p.Thr157Ser missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734733 c.480T>C synonymous_variant 1.0 rifampicin
nusG 734742 c.489T>C synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.97 rifampicin
nusG 734764 p.Ala171Thr missense_variant 0.98 rifampicin
nusG 734778 c.525G>C synonymous_variant 0.93 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.95 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.95 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.96 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.97 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.97 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.98 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.98 rifampicin
nusG 734877 c.624C>T synonymous_variant 0.99 rifampicin
nusG 734882 p.Ala210Gly missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734925 c.672C>T synonymous_variant 0.97 rifampicin
nusG 734931 c.678A>G synonymous_variant 0.97 rifampicin
nusG 734940 c.687G>A synonymous_variant 0.95 rifampicin
nusG 734943 c.690G>C synonymous_variant 0.94 rifampicin
nusG 734949 c.696T>C synonymous_variant 0.94 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.95 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>G synonymous_variant 1.0 rifampicin
rpoB 760124 c.318C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.96 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.96 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>A synonymous_variant 0.98 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.89 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.98 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.97 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.98 rifampicin
rpoB 760514 c.708C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.99 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.98 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.98 rifampicin Uncertain significance
rpoB 760568 c.762G>C synonymous_variant 0.98 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.99 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 0.97 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760674 c.868T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760683 c.877_879delTTGinsCC frameshift_variant&missense_variant 0.96 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760727 c.921C>T synonymous_variant 0.88 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.87 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.98 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 0.98 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.98 rifampicin
rpoB 761006 c.1200C>T synonymous_variant 0.98 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>G synonymous_variant 1.0 rifampicin
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.98 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 0.98 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.97 rifampicin
rpoB 761309 c.1503C>T synonymous_variant 0.97 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>A synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761437 p.Ala544Asp missense_variant 1.0 rifampicin
rpoB 761451 p.Val549Thr missense_variant 1.0 rifampicin
rpoB 761457 p.Pro551Ala missense_variant 1.0 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 1.0 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.98 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 1.0 rifampicin
rpoB 761843 c.2037C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 0.95 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.97 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.97 rifampicin
rpoB 761870 c.2064C>T synonymous_variant 0.97 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.97 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.97 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.98 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.98 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.98 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.98 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.99 rifampicin Uncertain significance
rpoB 762140 c.2334G>C synonymous_variant 0.99 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.99 rifampicin
rpoB 762146 c.2340G>A synonymous_variant 0.99 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.99 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.99 rifampicin
rpoB 762278 c.2472C>G synonymous_variant 0.97 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.98 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762335 c.2529C>A synonymous_variant 0.98 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762368 c.2562G>A synonymous_variant 0.97 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.97 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.95 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.95 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762425 c.2619C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.97 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762590 c.-780C>G upstream_gene_variant 1.0 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 1.0 rifampicin
rpoC 762605 c.-765T>C upstream_gene_variant 1.0 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 1.0 rifampicin
rpoB 762630 p.Ala942Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 762634 p.Ala943Gly missense_variant 1.0 rifampicin
rpoB 762638 p.Lys944Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 762641 c.-729G>A upstream_gene_variant 1.0 rifampicin
rpoC 762647 c.-723G>C upstream_gene_variant 1.0 rifampicin
rpoC 762656 c.-714C>G upstream_gene_variant 1.0 rifampicin
rpoB 762661 p.Arg952Lys missense_variant 1.0 rifampicin Uncertain significance
rpoB 762663 c.2857C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762669 c.2863_2865delGACinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762680 c.-690C>G upstream_gene_variant 1.0 rifampicin
rpoB 762683 p.Glu959Asp missense_variant 1.0 rifampicin
rpoB 762687 p.Gln961Glu missense_variant 1.0 rifampicin
rpoC 762701 c.-669T>C upstream_gene_variant 1.0 rifampicin
rpoC 762704 c.-666G>T upstream_gene_variant 1.0 rifampicin
rpoB 762725 c.2919C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762741 c.-629C>T upstream_gene_variant 0.97 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 0.97 rifampicin
rpoB 762759 p.Cys985Ala missense_variant 0.97 rifampicin
rpoC 762776 c.-594C>G upstream_gene_variant 0.93 rifampicin
rpoB 762781 p.Gly992Asp missense_variant 0.95 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 0.95 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.95 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.97 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762819 p.Phe1005Leu missense_variant 0.97 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.96 rifampicin
rpoB 762959 c.3153G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762971 c.3165G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.98 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763193 c.-177C>T upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763271 c.-99C>T upstream_gene_variant 1.0 rifampicin
rpoC 763274 c.-96G>C upstream_gene_variant 1.0 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.97 rifampicin
rpoC 763417 c.48C>G synonymous_variant 0.98 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.98 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.98 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763627 c.258G>A synonymous_variant 0.99 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>T synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763718 c.349C>T synonymous_variant 1.0 rifampicin
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763729 c.360G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763783 c.414G>C synonymous_variant 1.0 rifampicin
rpoC 763792 c.423G>A synonymous_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763825 c.456G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>A synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763870 c.501C>T synonymous_variant 0.98 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 c.507A>G synonymous_variant 0.98 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 0.98 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.98 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 0.97 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.97 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.96 rifampicin
rpoC 763949 c.580C>A synonymous_variant 0.97 rifampicin
rpoC 763978 c.609C>G synonymous_variant 0.98 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.99 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764159 c.790C>T synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 1.0 rifampicin
rpoC 764246 c.877_879delCTCinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.98 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.98 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.98 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.98 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764359 c.990C>T synonymous_variant 0.99 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.98 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764419 c.1050C>G synonymous_variant 0.98 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764449 c.1080G>C synonymous_variant 0.98 rifampicin
rpoC 764455 c.1086G>C synonymous_variant 0.98 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.98 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.98 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.98 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764932 c.1563C>G synonymous_variant 0.97 rifampicin
rpoC 764953 c.1584G>C synonymous_variant 0.97 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.93 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>G synonymous_variant 0.96 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>T synonymous_variant 0.95 rifampicin
rpoC 765055 c.1686C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.93 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.93 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 0.93 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765300 p.Val644Ala missense_variant 0.97 rifampicin Uncertain significance
rpoC 765305 p.Ile646Leu missense_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 c.1957_1959delCACinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765329 c.1960_1961delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765346 c.1977C>T synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765373 c.2004G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 1.0 rifampicin
rpoC 765409 c.2040T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765413 p.Pro682Ala missense_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.99 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.96 rifampicin
rpoC 765535 c.2166C>T synonymous_variant 0.97 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.97 rifampicin
rpoC 765550 c.2181C>T synonymous_variant 0.97 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.97 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.97 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.99 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765673 c.2304C>T synonymous_variant 0.99 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 0.96 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.99 rifampicin Uncertain significance
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.99 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.99 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>G synonymous_variant 1.0 rifampicin
rpoC 765850 c.2481G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.97 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.99 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 0.97 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>A synonymous_variant 0.98 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766079 c.2710_2712delCGTinsAC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.95 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.98 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.97 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 0.96 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766150 c.2781C>G synonymous_variant 1.0 rifampicin
rpoC 766163 p.Glu932Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 766167 p.Ala933Asp missense_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766291 c.2922G>C synonymous_variant 1.0 rifampicin
rpoC 766306 c.2937C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>T synonymous_variant 0.97 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.97 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.98 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.98 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.98 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.98 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.99 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>A synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.97 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.97 rifampicin
rpoC 766540 c.3171C>T synonymous_variant 0.94 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.96 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.95 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.96 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 0.95 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.95 rifampicin
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.97 rifampicin
rpoC 766645 p.Glu1092Asp missense_variant 0.95 rifampicin Not assoc w R
rpoC 766657 c.3288A>G synonymous_variant 0.96 rifampicin
rpoC 766658 c.3289_3291delCGGinsGA frameshift_variant&missense_variant 0.94 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.96 rifampicin
rpoC 766669 c.3300C>A synonymous_variant 0.94 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.96 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.94 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.98 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.98 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 0.97 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.98 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.98 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.95 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766923 p.Glu1185Gly missense_variant 0.95 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.98 rifampicin
rpoC 766945 c.3576A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.99 rifampicin
rpoC 767032 c.3663G>C synonymous_variant 0.98 rifampicin
rpoC 767035 c.3666G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.99 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
mmpL5 775847 c.2634G>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.97 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775913 c.2568C>G synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 775949 c.2532G>T synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.86 clofazimine
bedaquiline
mmpL5 775973 c.2506_2508delTTGinsCC frameshift_variant&missense_variant 0.85 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775981 p.Leu834Met missense_variant 0.97 clofazimine
bedaquiline
mmpL5 775994 c.2487C>T synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775997 c.2484T>G synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776003 c.2476_2478delATCinsCG frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776039 c.2442C>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 776665 p.Thr606Ala missense_variant 0.73 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776672 c.1809G>T synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 776678 c.1803G>T synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776693 c.1788C>G synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776711 c.1770C>T synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776735 c.1746C>T synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 776744 c.1737C>G synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.91 clofazimine
bedaquiline
mmpL5 777182 c.1299C>G synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777191 c.1290C>A synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777209 c.1272C>T synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777214 p.Ala423Thr missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777225 p.Asn419Thr missense_variant 0.88 clofazimine
bedaquiline
mmpL5 777245 c.1236G>C synonymous_variant 0.91 clofazimine
bedaquiline
mmpL5 777251 c.1230C>A synonymous_variant 0.9 clofazimine
bedaquiline
rpsL 781128 c.-432C>G upstream_gene_variant 0.95 streptomycin
rpsL 781134 c.-426T>G upstream_gene_variant 0.96 streptomycin
rpsL 781138 c.-422C>G upstream_gene_variant 0.96 streptomycin
rpsL 781143 c.-417T>G upstream_gene_variant 0.97 streptomycin
rpsL 781161 c.-399G>A upstream_gene_variant 0.97 streptomycin
rpsL 781164 c.-396T>C upstream_gene_variant 0.97 streptomycin
rpsL 781170 c.-390G>C upstream_gene_variant 0.97 streptomycin
rpsL 781173 c.-387A>G upstream_gene_variant 0.97 streptomycin
rpsL 781179 c.-381T>C upstream_gene_variant 0.98 streptomycin
rpsL 781182 c.-378G>C upstream_gene_variant 0.98 streptomycin
rpsL 781185 c.-375T>C upstream_gene_variant 0.98 streptomycin
rpsL 781206 c.-354C>T upstream_gene_variant 1.0 streptomycin
rpsL 781209 c.-351C>G upstream_gene_variant 1.0 streptomycin
rpsL 781224 c.-336T>C upstream_gene_variant 1.0 streptomycin
rpsL 781227 c.-333C>G upstream_gene_variant 1.0 streptomycin
rpsL 781234 c.-326G>C upstream_gene_variant 1.0 streptomycin
rpsL 781240 c.-320A>T upstream_gene_variant 1.0 streptomycin
rpsL 781257 c.-303G>T upstream_gene_variant 1.0 streptomycin
rpsL 781260 c.-300G>C upstream_gene_variant 1.0 streptomycin
rpsL 781264 c.-296G>A upstream_gene_variant 1.0 streptomycin
rpsL 781270 c.-290A>C upstream_gene_variant 1.0 streptomycin
rpsL 781391 c.-169_-168insCGG upstream_gene_variant 0.8 streptomycin
rpsL 781571 c.12C>T synonymous_variant 0.95 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.99 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.96 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.97 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.96 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.97 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.96 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.97 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.97 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.95 streptomycin
rpsL 781817 c.258G>A synonymous_variant 0.96 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.96 streptomycin
rpsL 781826 c.267C>T synonymous_variant 0.95 streptomycin Not assoc w R - Interim
rpsL 781832 c.273T>C synonymous_variant 0.96 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.97 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.96 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.96 streptomycin
rpsL 781871 c.312G>A synonymous_variant 0.96 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.96 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.98 streptomycin
rpsL 781910 c.351C>T synonymous_variant 0.99 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.99 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.99 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.99 streptomycin
rplC 800474 c.-335_-334insG upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 0.97 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.98 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.96 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 0.98 linezolid
rplC 800555 c.-254C>A upstream_gene_variant 0.97 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.99 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.99 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.99 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.98 linezolid
rplC 800672 c.-137G>A upstream_gene_variant 0.98 linezolid
rplC 800690 c.-119C>G upstream_gene_variant 0.98 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.98 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.99 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.96 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.98 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 0.96 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 0.93 linezolid
rplC 800808 c.-1delAinsTC upstream_gene_variant 0.93 linezolid
rplC 800815 c.7C>A synonymous_variant 0.92 linezolid
rplC 800820 c.12G>A synonymous_variant 0.93 linezolid
rplC 800829 c.21C>G synonymous_variant 0.96 linezolid
rplC 800844 c.36T>C synonymous_variant 0.95 linezolid
rplC 800856 c.48A>G synonymous_variant 0.97 linezolid
rplC 800865 c.57A>G synonymous_variant 0.96 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.95 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.95 linezolid
rplC 800877 c.69A>C synonymous_variant 0.95 linezolid
rplC 800880 c.72A>C synonymous_variant 0.93 linezolid
rplC 800901 c.93C>G synonymous_variant 0.98 linezolid
rplC 800904 c.96G>C synonymous_variant 0.89 linezolid
rplC 800916 c.108A>G synonymous_variant 0.96 linezolid
rplC 800934 c.126C>G synonymous_variant 0.96 linezolid
rplC 800937 c.129A>G synonymous_variant 0.96 linezolid
rplC 800946 c.138T>C synonymous_variant 0.95 linezolid
rplC 800949 c.141T>C synonymous_variant 0.94 linezolid
rplC 800967 c.159C>G synonymous_variant 0.94 linezolid
rplC 800970 c.162T>C synonymous_variant 0.94 linezolid Not assoc w R - Interim
rplC 800973 c.165C>G synonymous_variant 0.94 linezolid
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 0.92 linezolid
rplC 801135 c.327C>T synonymous_variant 0.92 linezolid
rplC 801136 p.Ser110Ala missense_variant 1.0 linezolid
rplC 801141 c.333C>T synonymous_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801159 c.351C>G synonymous_variant 1.0 linezolid
rplC 801162 c.354C>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801246 c.438C>G synonymous_variant 0.98 linezolid
rplC 801249 c.441T>G synonymous_variant 0.98 linezolid
rplC 801255 c.447C>T synonymous_variant 0.98 linezolid
rplC 801270 c.462T>C synonymous_variant 0.97 linezolid
rplC 801276 c.468G>T synonymous_variant 0.97 linezolid
rplC 801285 c.477G>C synonymous_variant 0.97 linezolid
rplC 801288 c.480G>C synonymous_variant 0.97 linezolid
rplC 801303 c.495G>T synonymous_variant 0.98 linezolid
rplC 801312 c.504G>C synonymous_variant 0.98 linezolid
rplC 801333 c.525G>A synonymous_variant 0.98 linezolid
rplC 801339 c.531T>G synonymous_variant 0.97 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.97 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.98 linezolid
rplC 801396 c.588T>C synonymous_variant 0.97 linezolid
rplC 801400 c.592_594delGTTinsAC frameshift_variant&missense_variant 0.96 linezolid
rplC 801405 c.597T>C synonymous_variant 0.96 linezolid
rplC 801423 c.615G>C synonymous_variant 0.95 linezolid
rplC 801426 c.618C>G synonymous_variant 0.94 linezolid
rplC 801438 c.630T>C synonymous_variant 0.88 linezolid
fbiC 1303242 c.312T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303251 c.321C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303257 c.327C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303263 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303268 p.Lys113Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303272 c.342A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303281 c.351A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303284 c.354T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303285 p.Ser119Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303288 p.Ser120Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303292 p.Thr121Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303296 c.366T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303302 c.372A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303440 c.510G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303542 c.612C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303713 c.783C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303722 c.792C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303782 c.852C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303812 c.882C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303815 c.885C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303827 c.897A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303844 p.Ala305Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303896 c.966G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303903 c.973C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303908 c.978C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303938 c.1008C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304016 c.1086C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304104 c.1174C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304154 c.1224G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304165 p.Gly412Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304199 c.1269C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304220 c.1290G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304223 c.1293G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304255 p.Ala442Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304261 p.Trp444Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304415 c.1485G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304424 c.1494C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304436 c.1506G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304439 c.1509G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304444 p.Ala505Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304484 c.1554C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304487 c.1557C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304547 c.1617C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304577 c.1647C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304589 c.1659C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304802 c.1872G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304805 c.1875G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304889 c.1959G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305106 c.2176C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305114 p.Asp728Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305318 c.2388C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305411 c.2481C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305414 c.2484G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305420 c.2490C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305426 c.2496G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305431 p.Val834Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305441 c.2511C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364661 c.249C>G synonymous_variant 0.85 pyrazinamide
sigE 1364667 c.255T>C synonymous_variant 0.92 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.93 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 0.93 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.92 pyrazinamide
sigE 1364694 c.282G>C synonymous_variant 0.92 pyrazinamide
sigE 1364697 c.285G>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364718 c.306C>G synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364910 c.498G>C synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 c.510G>A synonymous_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 1.0 pyrazinamide
sigE 1364950 c.538_540delGCAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1365000 c.588G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
embR 1416307 c.1041C>G synonymous_variant 1.0 ethambutol
embR 1416313 c.1035A>G synonymous_variant 1.0 ethambutol
embR 1416327 p.Ile341Leu missense_variant 1.0 ethambutol
embR 1416330 p.Val340Ile missense_variant 1.0 ethambutol
embR 1416335 p.Asn338Ser missense_variant 1.0 ethambutol
embR 1416358 c.990C>A synonymous_variant 1.0 ethambutol
embR 1416367 c.981C>G synonymous_variant 1.0 ethambutol
embR 1416637 c.711C>T synonymous_variant 1.0 ethambutol
embR 1416643 c.705G>C synonymous_variant 1.0 ethambutol
embR 1416646 c.702A>G synonymous_variant 1.0 ethambutol
embR 1416652 c.696G>A synonymous_variant 1.0 ethambutol
embR 1416671 p.Gly226Ala missense_variant 1.0 ethambutol
embR 1416675 c.673C>T synonymous_variant 1.0 ethambutol
embR 1416679 c.669T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embR 1416688 c.660G>C synonymous_variant 1.0 ethambutol
embR 1416696 p.Ser218Thr missense_variant 1.0 ethambutol
embR 1416721 c.625_627delACAinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embR 1416731 p.Pro206Gln missense_variant 1.0 ethambutol
embR 1416736 c.612G>C synonymous_variant 1.0 ethambutol
embR 1416752 p.Phe199Ala missense_variant 1.0 ethambutol
embR 1416754 c.594A>C synonymous_variant 1.0 ethambutol
embR 1416760 c.588T>G synonymous_variant 1.0 ethambutol
embR 1417042 c.306G>A synonymous_variant 1.0 ethambutol
atpE 1460804 c.-241T>C upstream_gene_variant 0.95 bedaquiline
atpE 1460807 c.-238C>T upstream_gene_variant 0.97 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.98 bedaquiline
atpE 1460840 c.-205A>C upstream_gene_variant 0.98 bedaquiline
atpE 1460850 c.-195_-193delCTCinsAG upstream_gene_variant 0.97 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.93 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.97 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.97 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1461068 c.24C>T synonymous_variant 1.0 bedaquiline
atpE 1461071 c.27C>T synonymous_variant 1.0 bedaquiline
atpE 1461087 c.43_45delCTGinsAC frameshift_variant&missense_variant 0.93 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 0.93 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.93 bedaquiline
atpE 1461107 c.63C>A synonymous_variant 0.92 bedaquiline
atpE 1461113 c.69C>A synonymous_variant 0.94 bedaquiline
atpE 1461122 c.78C>T synonymous_variant 0.95 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.96 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.95 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.95 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.96 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.96 bedaquiline Uncertain significance
atpE 1461173 c.129C>G synonymous_variant 0.97 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.95 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
atpE 1461261 c.217C>T synonymous_variant 1.0 bedaquiline
atpE 1461275 c.231T>C synonymous_variant 0.95 bedaquiline
atpE 1461278 c.234A>T synonymous_variant 0.9 bedaquiline
atpE 1461286 p.Lys81Thr missense_variant 0.82 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471675 n.-171G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471684 n.-162A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471685 n.-161A>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471687 n.-159C>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472044 n.199G>A non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473684 n.27G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473943 n.286G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474029 n.372G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474060 n.403G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474664 n.1007G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474997 n.1340A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475019 n.1362T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475239 n.1582A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475622 n.1965G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476044 n.2387T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
inhA 1673490 c.-712A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673499 c.-703T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673502 c.-700C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673505 c.-697A>C upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673529 c.-673G>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673569 p.Val44Ile missense_variant 0.89 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673577 c.-625C>T upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.91 ethionamide
isoniazid Uncertain significance
inhA 1673586 c.-616C>T upstream_gene_variant 0.82 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673613 c.-589C>G upstream_gene_variant 0.83 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.95 ethionamide
isoniazid
inhA 1673652 c.-550C>A upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.95 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.95 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.9 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1673680 c.241_243delCCGinsGC frameshift_variant&missense_variant 0.9 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.92 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.92 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.9 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.91 ethionamide
isoniazid
inhA 1673754 c.-448C>T upstream_gene_variant 0.87 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.91 ethionamide
isoniazid
inhA 1673787 c.-415G>A upstream_gene_variant 0.92 ethionamide
isoniazid Uncertain significance
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674042 c.-160G>T upstream_gene_variant 0.93 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674069 c.-133G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674090 c.-112C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674111 c.-91G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674135 c.-67C>T upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1674136 p.Ser233Ala missense_variant 0.95 ethionamide
isoniazid
inhA 1674141 c.-61T>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674474 c.273G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674621 c.420C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674639 c.438C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674675 c.474C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674717 c.516C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674732 c.531C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674746 p.Tyr182Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674810 c.609C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674834 c.633C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674855 c.654C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674912 c.711G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674927 c.726G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674945 p.Asp248Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674981 c.780C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674993 c.792G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 1.0 ethionamide
isoniazid
rpsA 1833288 c.-254_-253delTGinsCA upstream_gene_variant 0.87 pyrazinamide
rpsA 1833295 c.-247C>A upstream_gene_variant 0.89 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.88 pyrazinamide
rpsA 1833319 c.-223C>G upstream_gene_variant 0.8 pyrazinamide
rpsA 1833516 c.-26A>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833541 c.-1T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833610 c.69C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.99 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.99 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>A synonymous_variant 1.0 pyrazinamide
rpsA 1833796 c.255G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.99 pyrazinamide
rpsA 1833970 c.429G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834072 c.531C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834204 c.663C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834259 c.718_720delCTAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
rpsA 1834264 c.723G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834411 c.870T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834451 c.910_912delTTGinsCC frameshift_variant&missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834459 c.918G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.99 pyrazinamide
rpsA 1834480 c.939C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834528 c.987T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834531 c.990C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834558 c.1017C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834636 c.1095C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 1.0 linezolid
tsnR 1853399 c.-207C>T upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.98 linezolid
tsnR 1853429 c.-177G>T upstream_gene_variant 0.96 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.96 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 0.96 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.95 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 0.93 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.93 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.93 linezolid
tsnR 1853474 c.-132C>T upstream_gene_variant 0.9 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.91 linezolid
tsnR 1853484 c.-122_-121delAGinsGC upstream_gene_variant 0.91 linezolid
tsnR 1853502 c.-104A>G upstream_gene_variant 0.82 linezolid
tsnR 1853510 c.-96G>C upstream_gene_variant 0.8 linezolid
tsnR 1853516 c.-90C>T upstream_gene_variant 0.83 linezolid
tsnR 1853954 p.Arg117Gly missense_variant 0.92 linezolid
tsnR 1853977 c.372G>C synonymous_variant 0.97 linezolid
tsnR 1853980 c.375A>C synonymous_variant 0.97 linezolid
tsnR 1854010 c.405G>C synonymous_variant 0.94 linezolid
tsnR 1854013 c.408G>C synonymous_variant 0.94 linezolid
tsnR 1854022 c.417C>G synonymous_variant 0.97 linezolid
tsnR 1854024 p.Ala140Gly missense_variant 0.97 linezolid
tsnR 1854030 p.Arg142His missense_variant 0.97 linezolid
tsnR 1854043 c.438A>T synonymous_variant 0.97 linezolid
tsnR 1854059 c.454C>T synonymous_variant 0.94 linezolid
tlyA 1917908 c.-32C>G upstream_gene_variant 1.0 capreomycin
tlyA 1917917 c.-23G>C upstream_gene_variant 1.0 capreomycin
tlyA 1917929 c.-11T>C upstream_gene_variant 1.0 capreomycin
tlyA 1917937 c.-3G>C upstream_gene_variant 1.0 capreomycin
tlyA 1917938 c.-2G>C upstream_gene_variant 1.0 capreomycin
tlyA 1917940 p.Val1Met missense_variant 1.0 capreomycin
tlyA 1917951 c.12T>C synonymous_variant 1.0 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 1.0 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 1.0 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 1.0 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>G synonymous_variant 1.0 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 1.0 capreomycin
tlyA 1918035 c.96G>C synonymous_variant 1.0 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 1.0 capreomycin
tlyA 1918047 c.108G>C synonymous_variant 1.0 capreomycin
tlyA 1918410 c.471C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
tlyA 1918422 c.483T>C synonymous_variant 1.0 capreomycin
tlyA 1918442 p.Val168Ala missense_variant 1.0 capreomycin
tlyA 1918454 p.Ser172Cys missense_variant 1.0 capreomycin
tlyA 1918457 p.Arg173Pro missense_variant 1.0 capreomycin
tlyA 1918459 p.Asp174Ser missense_variant 1.0 capreomycin
tlyA 1918464 c.525C>G synonymous_variant 1.0 capreomycin
tlyA 1918476 c.537A>C synonymous_variant 1.0 capreomycin
tlyA 1918477 p.Leu180Met missense_variant 1.0 capreomycin
tlyA 1918488 c.549G>A synonymous_variant 1.0 capreomycin
tlyA 1918503 c.564G>C synonymous_variant 1.0 capreomycin
bacA 2063254 p.Glu492Ala missense_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063259 p.Glu490Asp missense_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063265 p.Gly488Glu missense_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063271 c.1458G>A synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063275 p.His485Cys missense_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063280 c.1449C>G synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063286 c.1443G>C synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063289 c.1440A>C synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063538 c.1191A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063541 c.1188A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063544 c.1185C>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063550 c.1177_1179delTCCinsGG frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063556 c.1173T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063588 c.1141T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063601 c.1126_1128delAACinsGA frameshift_variant&missense_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2063610 c.1119C>A synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063613 c.1116T>C synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063619 c.1110G>A synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063631 c.1098T>C synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063641 p.Asp363Ala missense_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063649 c.1080G>T synonymous_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064141 c.588C>G synonymous_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064150 c.579T>C synonymous_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064156 c.573C>T synonymous_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064174 c.555C>T synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064177 c.552C>G synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064189 c.540G>C synonymous_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064192 c.535_537delGAAinsAC frameshift_variant&missense_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064207 c.522C>T synonymous_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064210 c.519A>G synonymous_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064240 c.487_489delCAAinsGT frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064243 c.486A>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064253 p.His159Ala missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064258 c.471A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064267 c.460_462delAGGinsCT frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064273 c.456C>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064882 c.-154C>G upstream_gene_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064883 c.-157_-155delGACinsAT upstream_gene_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064897 c.-169C>G upstream_gene_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064906 c.-178G>A upstream_gene_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064942 c.-214G>A upstream_gene_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064963 c.-235G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064975 c.-247G>C upstream_gene_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101702 c.1341G>A synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101708 c.1335G>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101732 c.1311T>C synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2101735 c.1308A>G synonymous_variant 0.84 ethionamide
delamanid
isoniazid
ndh 2101753 c.1290C>G synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.92 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>C synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101800 c.1243C>T synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101816 c.1227C>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101838 p.Ala402Val missense_variant 0.98 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101854 c.1189C>T synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101858 c.1185T>C synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101876 c.1167C>G synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2101879 c.1164C>T synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101888 c.1153_1155delGTTinsCG frameshift_variant&missense_variant 0.92 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101891 c.1152C>G synonymous_variant 0.92 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101915 c.1128T>C synonymous_variant 0.92 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101924 c.1119T>G synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2101930 c.1113C>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101954 c.1089G>A synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101966 c.1077T>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101980 p.Asn355Asp missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101993 c.1050A>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102009 p.Ser345Asn missense_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102020 c.1023A>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102023 c.1020G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102026 c.1017G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102044 c.999G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102047 c.996G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102050 c.993T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102053 c.990G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102059 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102065 c.978G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102068 c.975T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102071 c.972C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102083 c.958_960delGTGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102086 c.957G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102110 c.933T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102245 c.798C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102254 c.789C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102287 c.756C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102302 c.741G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102692 c.351C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102713 c.330C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>G synonymous_variant 0.96 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102731 c.312C>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102737 c.306A>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102743 c.300C>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102752 c.291G>A synonymous_variant 0.96 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102755 p.Gly96Asn missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102785 c.256_258delTTGinsCC frameshift_variant&missense_variant 0.97 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102791 c.252A>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102800 c.243T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102804 p.Arg80His missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102812 c.231T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102817 c.226C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102821 c.222C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102833 c.210G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102836 c.207T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102845 c.198A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102857 c.186T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102883 c.160C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102911 c.132G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102929 c.114T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102962 c.81A>C synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2102965 c.78G>A synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102974 c.69G>T synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102977 c.66T>A synonymous_variant 0.95 ethionamide
delamanid
isoniazid
katG 2155113 c.999C>G synonymous_variant 0.88 isoniazid
katG 2155119 p.Ser331Thr missense_variant 0.82 isoniazid
katG 2155131 c.981A>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
katG 2155144 p.Asn323Pro missense_variant 0.88 isoniazid
katG 2155152 c.960A>C synonymous_variant 0.88 isoniazid
katG 2155155 c.957C>G synonymous_variant 0.88 isoniazid
katG 2155561 p.Gly184Ala missense_variant 1.0 isoniazid
katG 2155569 c.543C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155572 c.540G>C synonymous_variant 1.0 isoniazid
katG 2155581 c.531C>A synonymous_variant 1.0 isoniazid
katG 2155590 c.522A>G synonymous_variant 1.0 isoniazid
katG 2155617 c.495T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155623 c.489C>T synonymous_variant 1.0 isoniazid
katG 2155626 c.486G>C synonymous_variant 1.0 isoniazid
katG 2155632 c.480A>C synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155659 c.453C>G synonymous_variant 1.0 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>C synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155725 c.387C>T synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
katG 2155747 p.Ala122Gly missense_variant 1.0 isoniazid
katG 2155764 c.348C>T synonymous_variant 1.0 isoniazid
katG 2155782 c.330C>G synonymous_variant 1.0 isoniazid
katG 2155785 c.327T>C synonymous_variant 1.0 isoniazid
katG 2155794 p.Ala106Ser missense_variant 1.0 isoniazid
katG 2155806 c.306T>C synonymous_variant 1.0 isoniazid
katG 2155845 p.Pro89Asp missense_variant 1.0 isoniazid
pncA 2289994 c.-753A>G upstream_gene_variant 0.77 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.77 pyrazinamide
pncA 2290000 c.-759C>T upstream_gene_variant 0.85 pyrazinamide
pncA 2290006 c.-765T>C upstream_gene_variant 0.88 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.89 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 0.9 pyrazinamide
pncA 2290034 c.-793C>G upstream_gene_variant 0.88 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 0.9 pyrazinamide
pncA 2290072 c.-831T>C upstream_gene_variant 0.9 pyrazinamide
pncA 2290075 c.-834C>G upstream_gene_variant 0.93 pyrazinamide
pncA 2290084 c.-843T>C upstream_gene_variant 0.96 pyrazinamide
pncA 2290087 c.-846T>C upstream_gene_variant 0.96 pyrazinamide
pncA 2290096 c.-857_-855delATCinsGG upstream_gene_variant 0.96 pyrazinamide
kasA 2517917 c.-198G>C upstream_gene_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.99 isoniazid
kasA 2517956 c.-159G>A upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2517992 c.-123C>T upstream_gene_variant 0.94 isoniazid
kasA 2517995 c.-120C>G upstream_gene_variant 0.94 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 1.0 isoniazid
kasA 2518162 c.48G>A synonymous_variant 1.0 isoniazid
kasA 2518174 c.60A>G synonymous_variant 1.0 isoniazid
kasA 2518183 c.69G>A synonymous_variant 1.0 isoniazid
kasA 2518184 c.70_72delTCGinsGA frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518234 c.120G>A synonymous_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518273 c.159G>A synonymous_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 1.0 isoniazid
kasA 2518282 c.168A>G synonymous_variant 1.0 isoniazid
kasA 2518283 c.169_171delGCGinsCC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518300 c.186T>C synonymous_variant 1.0 isoniazid
kasA 2518312 p.Asp66Glu missense_variant 1.0 isoniazid
kasA 2518315 c.201G>C synonymous_variant 1.0 isoniazid
kasA 2518323 p.Ser70Asn missense_variant 1.0 isoniazid
kasA 2518408 c.294C>G synonymous_variant 0.9 isoniazid
kasA 2518413 p.Ser100Thr missense_variant 0.92 isoniazid
kasA 2518439 p.Ala109Thr missense_variant 0.92 isoniazid
kasA 2518444 c.330T>G synonymous_variant 0.97 isoniazid
kasA 2518450 c.336C>G synonymous_variant 0.97 isoniazid
kasA 2518459 c.345T>A synonymous_variant 0.98 isoniazid
kasA 2518462 c.348A>G synonymous_variant 0.98 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.98 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.98 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.98 isoniazid
kasA 2518483 c.369C>T synonymous_variant 0.98 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518513 c.399C>G synonymous_variant 1.0 isoniazid
kasA 2518519 c.405G>A synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>A synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.98 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.98 isoniazid
kasA 2518588 c.474T>A synonymous_variant 0.98 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.98 isoniazid
kasA 2518612 c.498C>G synonymous_variant 0.98 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.97 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.98 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.98 isoniazid
kasA 2518669 c.555C>T synonymous_variant 0.98 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.98 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.98 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.98 isoniazid
kasA 2518687 c.573C>T synonymous_variant 0.98 isoniazid
kasA 2518688 p.Val192Ile missense_variant 0.98 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.98 isoniazid
kasA 2518705 c.591T>G synonymous_variant 0.98 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.98 isoniazid
kasA 2518768 c.654C>T synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>T synonymous_variant 1.0 isoniazid
kasA 2518792 c.678C>G synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.98 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.98 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.98 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.96 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.98 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518912 c.798G>C synonymous_variant 1.0 isoniazid
kasA 2518921 c.807T>C synonymous_variant 1.0 isoniazid
kasA 2518939 c.825T>C synonymous_variant 1.0 isoniazid
kasA 2518942 c.828T>C synonymous_variant 1.0 isoniazid
kasA 2518960 c.846C>G synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 1.0 isoniazid
kasA 2519242 c.1128C>T synonymous_variant 1.0 isoniazid
kasA 2519251 c.1137G>A synonymous_variant 1.0 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 1.0 isoniazid
kasA 2519260 c.1146T>G synonymous_variant 1.0 isoniazid
kasA 2519264 p.Val384Ile missense_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
kasA 2519293 p.Asp393Glu missense_variant 1.0 isoniazid
kasA 2519298 p.Arg395Gln missense_variant 1.0 isoniazid
kasA 2519305 c.1191A>G synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
kasA 2519329 c.1215C>A synonymous_variant 1.0 isoniazid
kasA 2519332 c.1218C>G synonymous_variant 1.0 isoniazid
kasA 2519338 c.1224T>C synonymous_variant 1.0 isoniazid
kasA 2519341 c.1227G>C synonymous_variant 1.0 isoniazid
kasA 2519347 c.1233T>C synonymous_variant 1.0 isoniazid
kasA 2519364 c.1250G>A splice_region_variant&stop_retained_variant 1.0 isoniazid
ahpC 2726255 c.63T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726261 c.69G>C synonymous_variant 1.0 isoniazid
ahpC 2726264 c.72C>G synonymous_variant 1.0 isoniazid
ahpC 2726277 p.Lys29Arg missense_variant 1.0 isoniazid
ahpC 2726282 c.90G>A synonymous_variant 1.0 isoniazid
ahpC 2726303 c.111T>G synonymous_variant 1.0 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.98 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.98 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.98 isoniazid
ahpC 2726324 c.132A>C synonymous_variant 0.98 isoniazid
ahpC 2726336 c.144G>C synonymous_variant 0.98 isoniazid
ahpC 2726339 c.147G>C synonymous_variant 0.97 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.97 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 1.0 isoniazid
ahpC 2726378 c.186T>G synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726405 c.213C>G synonymous_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
ahpC 2726418 p.Glu76Ser missense_variant 1.0 isoniazid
ahpC 2726432 c.240C>A synonymous_variant 1.0 isoniazid
ahpC 2726435 c.243G>A synonymous_variant 1.0 isoniazid
ahpC 2726444 c.252G>C synonymous_variant 1.0 isoniazid
ahpC 2726447 c.255T>C synonymous_variant 1.0 isoniazid
ahpC 2726453 c.261T>C synonymous_variant 1.0 isoniazid
ahpC 2726627 c.435G>A synonymous_variant 0.94 isoniazid
ahpC 2726633 c.441C>A synonymous_variant 0.93 isoniazid
ahpC 2726639 c.447C>G synonymous_variant 0.87 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.87 isoniazid
ahpC 2726648 c.456T>A synonymous_variant 0.87 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 0.87 isoniazid
ahpC 2726657 c.465A>G synonymous_variant 0.87 isoniazid
ahpC 2726660 c.468C>T synonymous_variant 0.87 isoniazid
ahpC 2726666 c.474C>G synonymous_variant 0.88 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 0.88 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.94 isoniazid
ahpC 2726676 c.484C>T synonymous_variant 0.89 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.89 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.89 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.88 isoniazid
folC 2746360 c.1239T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.95 para-aminosalicylic_acid
folC 2746399 c.1200C>G synonymous_variant 0.95 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.95 para-aminosalicylic_acid
folC 2746420 c.1179A>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746448 p.Asp384Gly missense_variant 0.83 para-aminosalicylic_acid
folC 2746450 p.Gly383Thr missense_variant 0.8 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747006 p.Ser198Asp missense_variant 0.8 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747029 c.570G>C synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747037 p.Asn188Asp missense_variant 0.9 para-aminosalicylic_acid
folC 2747044 c.555C>T synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747083 c.516G>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 0.96 para-aminosalicylic_acid
folC 2747101 c.498G>A synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747122 c.477G>A synonymous_variant 0.95 para-aminosalicylic_acid
folC 2747129 p.Ala157Gly missense_variant 0.95 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747140 c.459G>A synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747317 c.282C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747343 p.Val86Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747350 c.249C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747363 p.Ala79Val missense_variant 1.0 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 1.0 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747412 p.Ser63Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747413 c.186C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747416 c.183A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747428 c.171G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747434 c.165C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747447 p.Ser51Thr missense_variant 0.97 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2747473 p.Arg42Lys missense_variant 1.0 para-aminosalicylic_acid
folC 2747482 c.117G>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747491 c.108A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747497 c.102C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747500 c.99A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747503 c.96T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747509 c.90T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747512 c.87G>A synonymous_variant 0.95 para-aminosalicylic_acid
Rv2477c 2782428 c.1615C>A synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782447 c.1596C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782450 c.1593C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.94 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782531 c.1512C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782573 c.1470C>T synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782695 c.1348A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782702 c.1341G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782705 c.1338G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782714 c.1329A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782720 c.1323T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782726 c.1317G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782729 c.1314A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782879 c.1164C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782885 c.1158G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782900 c.1143C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782913 p.Ser377Thr missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782954 c.1089G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782993 c.1050C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783107 c.936G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783110 c.933C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783134 c.909G>A synonymous_variant 0.98 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin
amikacin
Rv2477c 2783140 c.903C>A synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783152 c.891G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783155 c.888C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783193 p.Ser284Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783203 c.840C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783209 c.834G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 p.Gln263His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>A synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783287 c.756C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783320 c.723C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783341 c.702C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>T synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783365 c.678C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783431 p.Ser204Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783523 c.520C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783647 c.396C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783767 c.276C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783773 c.270A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783837 p.Thr69Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>T synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783950 c.93C>A synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783956 p.Tyr29Phe missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783968 c.75G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784301 c.-259T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784303 c.-261C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784311 c.-269T>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784315 c.-273G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784318 c.-276G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784333 c.-291G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784354 c.-312T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784357 c.-316_-315delTTinsAC upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784366 c.-324G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784395 c.-353C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784411 c.-369G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784414 c.-372A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784465 c.-423T>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784492 c.-450C>G upstream_gene_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784501 c.-461_-459delGGTinsAAC upstream_gene_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784512 c.-470A>G upstream_gene_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784513 c.-471C>T upstream_gene_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784519 c.-477G>C upstream_gene_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784546 c.-504G>A upstream_gene_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784551 c.-509G>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784558 c.-516A>G upstream_gene_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784563 c.-521G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784564 c.-522T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784570 c.-530_-528delAAAinsCG upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784583 c.-542_-541delTTinsCC upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784585 c.-543T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859486 c.933A>C synonymous_variant 0.91 clofazimine
bedaquiline
pepQ 2859490 p.Val310Ala missense_variant 0.92 clofazimine
bedaquiline
pepQ 2859507 c.912A>G synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859510 c.909T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859513 c.906A>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859525 c.894T>G synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859528 c.891T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859531 c.888C>T synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859534 c.885A>G synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859540 c.879A>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859543 c.876C>T synonymous_variant 0.94 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859546 c.873T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859554 p.His289Asn missense_variant 0.94 clofazimine
bedaquiline
pepQ 2859559 p.Gly287Ala missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859561 c.858C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859660 c.759G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859667 p.Gln251Arg missense_variant 0.97 clofazimine
bedaquiline
pepQ 2859678 c.741A>G synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859704 c.715T>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859708 c.711C>T synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859723 c.696T>C synonymous_variant 0.98 clofazimine Not assoc w R - Interim
bedaquiline
pepQ 2859732 c.687C>T synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859735 c.684G>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859747 c.672C>G synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859765 c.654G>C synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859778 p.Val214Asp missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859780 p.Gln213Thr missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859789 c.630G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859801 c.618G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859813 c.606C>T synonymous_variant 0.91 clofazimine
bedaquiline
pepQ 2859864 c.555T>C synonymous_variant 0.91 clofazimine
bedaquiline
pepQ 2859873 c.546T>C synonymous_variant 0.91 clofazimine
bedaquiline
pepQ 2859886 p.Ala178Gly missense_variant 0.9 clofazimine
bedaquiline
ribD 2986655 c.-184_-183delAAinsGG upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986661 c.-178G>A upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986664 c.-175A>C upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986667 c.-172T>C upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986670 c.-169_-168delATinsGA upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986688 c.-151C>G upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986700 c.-139C>T upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986703 c.-136A>C upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986714 c.-125G>A upstream_gene_variant 1.0 para-aminosalicylic_acid
Rv2680 2996329 c.225T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996350 c.-389C>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 1.0 capreomycin
Rv2681 2996363 c.-376C>T upstream_gene_variant 1.0 capreomycin
Rv2681 2996368 c.-371T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 1.0 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996404 c.-335T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 1.0 capreomycin
Rv2681 2996927 c.189T>C synonymous_variant 1.0 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 1.0 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 1.0 capreomycin
Rv2681 2996961 p.Ile75Val missense_variant 1.0 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 1.0 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 1.0 capreomycin
Rv2681 2996990 c.252G>C synonymous_variant 1.0 capreomycin
Rv2681 2997013 p.Gly92Ala missense_variant 1.0 capreomycin
Rv2681 2997021 c.283_285delTTGinsGC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997028 p.Val97Ala missense_variant 1.0 capreomycin
Rv2681 2997033 p.Ala99Arg missense_variant 1.0 capreomycin
Rv2681 2997038 c.300G>C synonymous_variant 1.0 capreomycin
Rv2681 2997054 p.Ser106Glu missense_variant 1.0 capreomycin
Rv2681 2997060 p.Asn108Asp missense_variant 1.0 capreomycin
Rv2681 2997078 p.Ser114Ala missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997098 c.360C>G synonymous_variant 1.0 capreomycin
Rv2681 2997101 c.363T>C synonymous_variant 1.0 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 1.0 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 1.0 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2997128 c.390A>G synonymous_variant 1.0 capreomycin
Rv2681 2997134 c.396A>G synonymous_variant 1.0 capreomycin
Rv2681 2997149 c.411T>G synonymous_variant 1.0 capreomycin
Rv2681 2997158 c.420C>G synonymous_variant 1.0 capreomycin
Rv2681 2997173 p.Asp145Glu missense_variant 1.0 capreomycin
Rv2681 2997176 c.438A>G synonymous_variant 1.0 capreomycin
Rv2681 2997189 p.Ala151Thr missense_variant 1.0 capreomycin
Rv2681 2997196 p.Val153Ala missense_variant 1.0 capreomycin
Rv2681 2997198 p.Glu154Gln missense_variant 1.0 capreomycin
Rv2681 2997206 c.468A>G synonymous_variant 1.0 capreomycin
Rv2681 2997209 c.471T>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2997212 c.474A>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2997218 c.480A>G synonymous_variant 1.0 capreomycin
Rv2681 2997219 c.481T>C synonymous_variant 1.0 capreomycin
Rv2681 2997222 p.Thr162Ala missense_variant 0.95 capreomycin
Rv2681 2997257 c.519C>A synonymous_variant 0.96 capreomycin
Rv2681 2997263 c.525A>G synonymous_variant 0.94 capreomycin
Rv2681 2997267 c.529_531delTCGinsGC frameshift_variant&missense_variant 0.93 capreomycin Uncertain significance
Rv2681 2997271 p.Ala178Glu missense_variant 0.93 capreomycin
Rv2681 2997278 c.540G>C synonymous_variant 0.94 capreomycin
Rv2681 2997287 c.549G>C synonymous_variant 0.94 capreomycin
Rv2681 2997290 c.552G>A synonymous_variant 0.94 capreomycin
Rv2681 2997291 c.553_555delTTGinsCC frameshift_variant&missense_variant 0.94 capreomycin Uncertain significance
Rv2681 2997302 c.564A>G synonymous_variant 0.94 capreomycin
Rv2681 2997317 c.579A>G synonymous_variant 0.87 capreomycin
Rv2681 2997324 p.Ala196Ser missense_variant 0.92 capreomycin
Rv2752c 3064839 c.1353C>T synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064856 p.Lys446Gln missense_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064872 c.1320T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064877 p.Ser439Ala missense_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064881 c.1309_1311delAGTinsTCC synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064884 c.1308C>T synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064887 c.1305A>G synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064893 c.1299C>G synonymous_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064896 c.1296T>G synonymous_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064962 c.1230C>G synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>C synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065004 c.1188G>C synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065040 c.1152C>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065055 c.1137T>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.91 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 0.89 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065154 c.1038G>A synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065166 c.1026C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065186 c.1006T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065187 c.1003_1005delGTGinsAT frameshift_variant&missense_variant 0.93 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065193 c.999C>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065196 c.996T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065205 c.987T>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065210 c.982T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065229 c.963G>C synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065235 c.957G>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065288 c.904T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065292 c.900T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065295 c.897A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065311 p.Thr294Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065313 c.879A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065324 p.Ala290Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065336 p.Leu286Val missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065337 c.855T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065346 c.846T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065352 c.840A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065355 c.837A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065367 c.823_825delCAAinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065370 c.820_822delAGGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065373 c.819A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065378 p.Val272Ile missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065381 p.Arg271Gly missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065403 c.789C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065418 c.774A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065442 c.750T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065454 c.738G>A synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065472 c.720C>G synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065487 c.705T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065513 c.679C>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065517 c.675C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065520 c.672G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065529 c.663G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065532 c.660A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065538 c.654G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065553 c.639A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065562 c.630T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065576 p.Ala206Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065594 c.598C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065610 c.580_582delACCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065634 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.543T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065659 p.Pro178Leu missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065666 c.526T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065667 c.525A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065699 p.Ile165Val missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065715 c.477T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065718 c.474G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065736 c.456C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065739 c.453G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065742 p.Thr150Ile missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065775 c.417T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065781 c.411C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065889 c.303G>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065898 c.294C>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065919 c.273G>T synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065922 c.270T>C synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065928 c.264G>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065940 c.252G>A synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065947 p.Gly82Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065949 c.243C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065957 c.235T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066071 c.121T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066118 p.Asn25Ser missense_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066425 c.-234A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066426 c.-235T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066429 c.-238G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066436 c.-246_-245delGGinsAA upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-268T>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066462 c.-271G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-274G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066468 c.-277C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066476 c.-285C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066480 c.-291_-289delGCCinsTG upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066483 c.-292T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066534 c.-343G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066564 c.-373C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066582 c.-392_-391delCCinsGT upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066601 c.-410C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066638 c.-447T>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066639 c.-448G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066644 c.-453T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066654 c.-463G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066676 c.-485C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066681 c.-490G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066687 c.-496G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066690 c.-499C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066696 c.-505T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066707 c.-516A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066741 c.-550T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066744 c.-553C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066747 c.-556A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066756 c.-567_-565delCGGinsTCC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066783 c.-592G>C upstream_gene_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066795 c.-604G>T upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066798 c.-607G>C upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066834 c.-643G>C upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066872 c.-681G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066885 c.-694G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066900 c.-709A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066905 c.-714T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066906 c.-715C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066910 c.-719C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066917 c.-726C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066925 c.-735_-734delATinsCG upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066927 c.-736A>G upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066933 c.-743_-742delGGinsAC upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066974 c.-783G>A upstream_gene_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067210 c.736T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067220 c.726G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067223 c.723G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 0.97 para-aminosalicylic_acid
thyX 3067250 c.696G>C synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067271 c.675G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067274 c.672C>A synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067280 c.666G>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067301 c.645C>T synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067310 c.636C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.99 para-aminosalicylic_acid
thyX 3067328 c.618G>C synonymous_variant 0.99 para-aminosalicylic_acid
thyX 3067331 c.615C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067360 p.Ile196Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067364 c.582C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067415 c.531C>T synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067433 c.513C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067442 c.504C>T synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067448 c.498G>A synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067586 c.360C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067607 p.Asp113Glu missense_variant 0.97 para-aminosalicylic_acid
thyX 3067613 c.333G>A synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067616 c.330C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067646 c.300C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.283_285delCGCinsAG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067676 c.270C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067724 c.222G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 1.0 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067823 c.123G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067880 c.66C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.97 para-aminosalicylic_acid
thyA 3073889 p.Ser195Ala missense_variant 0.97 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074028 c.444G>A synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.97 para-aminosalicylic_acid
thyA 3074056 p.Glu139Ser missense_variant 0.97 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074103 c.369C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074121 c.351T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074159 p.Ser105Thr missense_variant 0.93 para-aminosalicylic_acid
thyA 3074160 c.312A>C synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAC frameshift_variant&missense_variant 0.93 para-aminosalicylic_acid
thyA 3074166 c.306G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074262 c.210T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.93 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074305 p.Ala56Val missense_variant 0.96 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074322 c.150C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074325 c.147A>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074337 c.135C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074346 c.126C>T synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074364 c.108T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074372 p.Met34Leu missense_variant 1.0 para-aminosalicylic_acid
thyA 3074406 c.66C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074415 c.57C>A synonymous_variant 1.0 para-aminosalicylic_acid
ald 3087684 c.865_867delGCCinsAG frameshift_variant&missense_variant 0.73 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.9 cycloserine
ald 3087710 c.891C>T synonymous_variant 0.92 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.92 cycloserine
ald 3087726 p.Ala303Ser missense_variant 0.91 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.92 cycloserine
ald 3087734 c.915G>A synonymous_variant 0.96 cycloserine
ald 3087741 c.922_924delACGinsTC frameshift_variant&missense_variant 0.93 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 0.94 cycloserine
ald 3087776 c.957G>A synonymous_variant 0.93 cycloserine
ald 3087785 c.966C>G synonymous_variant 0.92 cycloserine
ald 3087786 p.Glu323Lys missense_variant 0.92 cycloserine
ald 3087791 c.972T>C synonymous_variant 0.91 cycloserine
ald 3087800 p.His327Gln missense_variant 0.94 cycloserine
fbiD 3339171 c.54C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiD 3339180 c.63G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiD 3339186 c.69A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiD 3339216 c.99G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiD 3339219 c.102T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiD 3339227 p.Asn37Ser missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiD 3339237 c.120G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiD 3339255 c.138G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339256 c.139T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339264 c.147C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiD 3339462 c.345C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiD 3339474 c.357A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiD 3339486 c.369G>A synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiD 3339492 c.375C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339501 c.384A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339513 c.396A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339516 c.399C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339519 p.His134Gln missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiD 3339615 c.498G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339617 p.Ser167Cys missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339639 c.522C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339642 c.525T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339643 p.Val176Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339651 c.534G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339654 c.537A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339657 c.540A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339660 c.543C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339666 c.549G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339681 c.564T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiD 3339690 c.573C>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
lpqB 3623273 c.1638T>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3623279 c.1632T>G synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623288 c.1623C>T synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3623309 c.1602A>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623312 p.Thr533Ile missense_variant 0.97 bedaquiline
rifampicin
lpqB 3623315 c.1596A>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623321 c.1590G>T synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623327 c.1584C>T synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623330 c.1581G>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623356 p.Leu519Ile missense_variant 0.98 bedaquiline
rifampicin
lpqB 3623360 c.1551A>G synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623363 c.1548T>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623366 c.1545T>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623378 c.1531_1533delGCCinsAG frameshift_variant&missense_variant 0.97 bedaquiline
rifampicin Uncertain significance
lpqB 3623387 c.1524C>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623408 c.1503C>T synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623411 c.1500T>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623428 c.1483T>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623441 c.1468_1470delTCCinsAG frameshift_variant&stop_gained 0.98 bedaquiline
rifampicin Uncertain significance
lpqB 3623444 c.1467T>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623447 c.1464G>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623474 c.1437C>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623489 c.1422C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623492 c.1419T>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623512 p.Gly467Ser missense_variant 0.97 bedaquiline
rifampicin
lpqB 3623518 p.Leu465Ile missense_variant 0.97 bedaquiline
rifampicin
lpqB 3623528 c.1383G>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623531 p.Gly460Ala missense_variant 0.96 bedaquiline
rifampicin
lpqB 3623552 c.1359G>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623555 c.1356G>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623558 c.1353C>T synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623561 c.1350T>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3623576 p.Asp445Glu missense_variant 0.88 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 0.93 bedaquiline
rifampicin
lpqB 3623587 p.Ala442Pro missense_variant 0.88 bedaquiline
rifampicin
lpqB 3623627 c.1284T>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623630 c.1281G>C synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3623639 c.1272A>G synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3623648 c.1263A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623660 c.1249_1251delATAinsTC frameshift_variant&synonymous_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3623665 p.Ala416Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623666 c.1245A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623676 p.Val412Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623684 c.1227T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623732 c.1177_1179delCTGinsAT frameshift_variant&missense_variant 0.88 bedaquiline
rifampicin Uncertain significance
lpqB 3623741 c.1170G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623753 c.1158G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624116 c.795A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624131 c.778_780delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624149 c.762C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624152 c.759C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624155 c.756G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624161 c.750G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624172 p.Val247Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624173 c.738A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624179 c.732C>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624200 c.711A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624320 c.591G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624335 c.576C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624341 c.570C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624347 c.564G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624365 c.546T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624371 c.540T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624386 c.525C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624416 c.495G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624671 c.240C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624680 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624707 c.204G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624713 c.198C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624725 c.186G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624770 c.141T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625030 c.-120G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625060 c.-150G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625066 c.-156G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625069 c.-159T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625096 c.-186C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625117 c.-207T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625135 c.-225A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625138 c.-228C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625189 c.-279A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625204 c.-294G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625263 p.Tyr451His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625273 c.-363C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625312 p.Arg434His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625315 c.-405G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625318 c.-408G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625327 c.-417A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625372 c.-462A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625381 c.-471T>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625387 c.-477T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625396 c.-486G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625407 p.Gln403Glu missense_variant 0.92 bedaquiline
rifampicin
mtrB 3625412 p.Ala401Asp missense_variant 0.92 bedaquiline
rifampicin
mtrB 3625419 p.Leu399Met missense_variant 0.87 bedaquiline
rifampicin
mtrB 3625420 p.Asp398Glu missense_variant 0.87 bedaquiline
rifampicin
lpqB 3625423 c.-513G>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625426 c.-516G>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625431 c.-521T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625438 c.-528T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625447 c.-537G>A upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625459 c.-549C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625465 c.-555T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625471 c.-561C>G upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625489 c.-579A>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3625497 c.1117T>C synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625510 c.-600T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625513 c.-603G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625518 c.-608T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625528 c.-618G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625531 c.-621C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625534 c.-624C>T upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625540 c.-630G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625549 c.-639G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625579 c.-669A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 0.98 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.98 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 0.98 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625720 c.-810G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625723 c.-813C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625777 c.-867C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625825 c.-915C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625852 c.-942A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625855 c.759G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625912 c.702G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625915 c.699G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625942 c.672C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626092 c.522T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626095 p.Glu173Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626101 p.Gln171His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626119 c.495C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626149 c.465C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626157 p.Ala153Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626170 c.444T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626747 c.-134G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626768 c.-155G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>A upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626867 c.-254G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626891 c.-278G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626924 c.-311G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626987 c.-374C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626990 c.-377G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626999 c.-386G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627170 c.-557C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin
mtrB 3627191 c.-578G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627196 c.-583C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627221 c.-608C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627227 c.123T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627296 c.-683T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627326 c.-713T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627861 c.-512C>T upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3627872 c.-523T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3627876 c.-527T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3627884 c.-535A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3627890 c.-541C>T upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3627893 c.-544T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3627920 c.-571A>C upstream_gene_variant 0.97 bedaquiline
rifampicin
fbiA 3640536 c.-7C>G upstream_gene_variant 0.93 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiA 3640541 c.-2A>G upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3640557 c.-978T>G upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiA 3640562 p.Ala7Val missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640566 c.-969T>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640569 c.-966A>G upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640575 c.-960C>T upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640584 c.-951C>G upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640587 c.-948C>T upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640593 c.-942C>T upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640596 c.-939G>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3640620 c.-915C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640827 c.-708T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640839 c.-696C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640851 c.-684G>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640857 c.-678G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640869 c.-666G>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640878 c.-657T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640879 c.337C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiB 3640890 c.-645C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640914 c.-621C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640930 p.Glu130Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640935 c.-600C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640938 c.-597A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640944 c.-591T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640956 c.-579G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640962 c.-573C>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640965 c.-570C>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640966 c.-569T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640974 c.432T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiB 3641046 c.-489T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641049 c.-486T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641070 c.-465C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641073 c.-462T>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641076 c.-459C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641078 p.Gln179Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641088 c.-447G>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3641097 c.-438T>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3641100 c.-435T>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3641103 c.-432T>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3641112 c.-423T>C upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fbiA 3641119 p.Ser193Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3641127 c.-408T>C upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3641139 c.-396G>C upstream_gene_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3641184 c.-351T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641187 c.-348T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641200 p.Ile220Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641223 c.-312C>G upstream_gene_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641226 c.-309G>C upstream_gene_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641229 c.-306T>C upstream_gene_variant 0.97 clofazimine
pretomanid
delamanid
fbiA 3641234 p.Ala231Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641239 c.-296T>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641246 p.Glu235Gly missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641250 c.-285A>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641256 c.-279A>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641260 p.Ile240Val missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641271 c.-264C>T upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641288 p.Glu249Gly missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641314 p.Thr258Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641325 c.-210G>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641328 c.-207T>G upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641331 c.-204C>A upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641334 c.-201G>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641337 c.-198G>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiA 3641340 p.Asp266Glu missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiA 3641351 p.Ala270Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641355 c.-180T>G upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641358 c.-177G>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641373 c.-162C>G upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641961 p.Thr143Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641987 c.453C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641993 c.459A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642020 c.486T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiB 3642026 c.492A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiB 3642035 c.501T>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3642038 c.504C>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiB 3642560 c.1026T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642572 c.1038A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642588 c.1054C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3642614 c.1080C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3642634 p.Asp367Gly missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642647 c.1113C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3642683 c.1149C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3642696 c.1162C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642710 c.1176G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642758 c.1224C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642763 p.Asp410Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642770 c.1236G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642773 p.Asp413Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642779 c.1245A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642780 p.Val416Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642785 c.1251C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642815 c.1281A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
alr 3841010 c.411A>G synonymous_variant 1.0 cycloserine
alr 3841018 p.Leu135Val missense_variant 1.0 cycloserine
alr 3841028 c.393G>C synonymous_variant 0.92 cycloserine
alr 3841033 p.Val130Ile missense_variant 1.0 cycloserine
alr 3841036 p.Gln129Glu missense_variant 0.92 cycloserine
alr 3841037 c.384G>C synonymous_variant 1.0 cycloserine
alr 3841046 c.375G>C synonymous_variant 0.95 cycloserine
alr 3841058 c.363G>C synonymous_variant 0.96 cycloserine
alr 3841069 p.Ile118Leu missense_variant 1.0 cycloserine
alr 3841079 c.342T>C synonymous_variant 1.0 cycloserine
alr 3841100 c.321A>G synonymous_variant 1.0 cycloserine
alr 3841106 c.315T>C synonymous_variant 1.0 cycloserine
alr 3841109 c.312C>G synonymous_variant 1.0 cycloserine
alr 3841112 c.309T>C synonymous_variant 1.0 cycloserine
alr 3841115 c.306T>C synonymous_variant 1.0 cycloserine
alr 3841127 c.294A>G synonymous_variant 1.0 cycloserine
alr 3841229 c.192G>C synonymous_variant 1.0 cycloserine
alr 3841232 c.189G>T synonymous_variant 1.0 cycloserine
alr 3841242 p.Gln60Arg missense_variant 1.0 cycloserine
alr 3841248 p.His58Pro missense_variant 1.0 cycloserine
alr 3841250 c.171C>T synonymous_variant 1.0 cycloserine
alr 3841262 c.159T>C synonymous_variant 1.0 cycloserine
alr 3841286 c.135T>C synonymous_variant 1.0 cycloserine
alr 3841289 c.132T>G synonymous_variant 1.0 cycloserine
alr 3841298 c.123T>C synonymous_variant 1.0 cycloserine
alr 3841304 c.115_117delATGinsGC frameshift_variant&missense_variant 1.0 cycloserine
rpoA 3877482 c.1026C>G synonymous_variant 1.0 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 1.0 rifampicin
rpoA 3877513 p.Thr332Ser missense_variant 1.0 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877524 c.984C>G synonymous_variant 1.0 rifampicin
rpoA 3877530 c.978C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877548 c.960C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877551 c.957G>A synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877587 c.921A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.99 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.99 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.98 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 1.0 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 0.97 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>T synonymous_variant 0.97 rifampicin
rpoA 3877794 c.714G>T synonymous_variant 0.97 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.97 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.97 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.97 rifampicin
rpoA 3877881 c.627G>A synonymous_variant 0.97 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.95 rifampicin
rpoA 3877899 p.Ser203Thr missense_variant 0.95 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.96 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.95 rifampicin
rpoA 3877986 c.522G>C synonymous_variant 0.96 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.95 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.97 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.97 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.97 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>C synonymous_variant 0.97 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 0.97 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.98 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.98 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.97 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 0.97 rifampicin
rpoA 3878079 c.429C>G synonymous_variant 0.97 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.97 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.97 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.97 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.98 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.98 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.98 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Ala missense_variant 1.0 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878358 c.150C>G synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 1.0 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 1.0 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878415 c.93C>T synonymous_variant 1.0 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 1.0 rifampicin
rpoA 3878460 c.48C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878471 p.Val13Ile missense_variant 1.0 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 1.0 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 1.0 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 1.0 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 1.0 rifampicin
rpoA 3878665 c.-158A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878698 c.-191A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 0.97 rifampicin
rpoA 3878704 c.-197C>G upstream_gene_variant 0.98 rifampicin
rpoA 3878725 c.-220_-218delCTAinsTG upstream_gene_variant 0.98 rifampicin
rpoA 3878728 c.-221G>A upstream_gene_variant 0.98 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.98 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoA 3878749 c.-242G>C upstream_gene_variant 0.98 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.97 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.97 rifampicin
rpoA 3878776 c.-269G>C upstream_gene_variant 0.97 rifampicin
rpoA 3878785 c.-278T>C upstream_gene_variant 0.97 rifampicin
rpoA 3878794 c.-287G>C upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.97 rifampicin
rpoA 3878806 c.-299C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878826 c.-319A>T upstream_gene_variant 1.0 rifampicin
rpoA 3878832 c.-325C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878839 c.-332C>T upstream_gene_variant 0.95 rifampicin
rpoA 3878842 c.-335G>C upstream_gene_variant 0.95 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.98 rifampicin
rpoA 3878875 c.-368C>T upstream_gene_variant 0.92 rifampicin Uncertain significance
rpoA 3878878 c.-371T>C upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 0.91 rifampicin
rpoA 3878889 c.-382A>G upstream_gene_variant 0.9 rifampicin
rpoA 3878894 c.-387A>G upstream_gene_variant 0.88 rifampicin
rpoA 3878908 c.-402_-401delACinsCG upstream_gene_variant 0.84 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.94 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.93 rifampicin
rpoA 3878924 c.-417G>C upstream_gene_variant 0.84 rifampicin
rpoA 3878929 c.-422G>C upstream_gene_variant 0.84 rifampicin
rpoA 3878935 c.-428C>T upstream_gene_variant 0.94 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.94 rifampicin
rpoA 3878953 c.-446C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878977 c.-470C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879006 c.-499A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.95 rifampicin
rpoA 3879016 c.-509A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879034 c.-528_-527delAGinsGT upstream_gene_variant 0.94 rifampicin
rpoA 3879037 c.-532_-530delCGGinsGC upstream_gene_variant 0.94 rifampicin
rpoA 3879041 c.-534T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879049 c.-542A>G upstream_gene_variant 0.96 rifampicin
rpoA 3879079 c.-572A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879151 c.-644C>T upstream_gene_variant 0.98 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879172 c.-665C>T upstream_gene_variant 0.99 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.97 rifampicin
rpoA 3879220 c.-713G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 1.0 rifampicin
ddn 3986633 c.-211C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986636 c.-208C>A upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986660 c.-184C>T upstream_gene_variant 0.97 delamanid
pretomanid
ddn 3986667 c.-177_-175delCTCinsACG upstream_gene_variant 0.97 delamanid
pretomanid
ddn 3986672 c.-172G>C upstream_gene_variant 0.97 delamanid
pretomanid
ddn 3986681 c.-163C>G upstream_gene_variant 0.97 delamanid
pretomanid
ddn 3986693 c.-151C>G upstream_gene_variant 0.92 delamanid
pretomanid
ddn 3986696 c.-148G>C upstream_gene_variant 0.9 delamanid
pretomanid
ddn 3986951 c.108T>C synonymous_variant 0.79 delamanid
pretomanid
ddn 3986960 c.117C>G synonymous_variant 0.88 delamanid
pretomanid
ddn 3986963 c.120C>A synonymous_variant 0.89 delamanid
pretomanid
ddn 3986978 c.135G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3986984 c.141G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987015 p.Gln58Glu missense_variant 1.0 delamanid
pretomanid
ddn 3987023 c.180G>C synonymous_variant 0.96 delamanid
pretomanid
ddn 3987026 c.183C>G synonymous_variant 0.96 delamanid
pretomanid
ddn 3987028 p.Asn62Ser missense_variant 0.96 delamanid
pretomanid
ddn 3987035 c.192C>G synonymous_variant 0.96 delamanid
pretomanid
ddn 3987041 c.198C>T synonymous_variant 0.97 delamanid
pretomanid
ddn 3987055 p.Gly71Asp missense_variant 0.97 delamanid
pretomanid
ddn 3987062 c.219C>G synonymous_variant 0.97 delamanid
pretomanid
ddn 3987074 c.231C>G synonymous_variant 0.98 delamanid
pretomanid
ddn 3987091 p.Glu83Ala missense_variant 0.98 delamanid Uncertain significance
pretomanid
ddn 3987095 c.252G>A synonymous_variant 0.98 delamanid Not assoc w R - Interim
pretomanid
ddn 3987119 c.276C>G synonymous_variant 0.98 delamanid
pretomanid
ddn 3987143 c.300A>G synonymous_variant 1.0 delamanid Not assoc w R - Interim
pretomanid
ddn 3987155 c.312G>A synonymous_variant 1.0 delamanid
pretomanid
ddn 3987158 c.315A>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987164 c.321G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987170 c.327T>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987173 c.330C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987182 c.339C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987185 c.342G>C synonymous_variant 1.0 delamanid
pretomanid
clpC1 4038239 c.2466T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038248 c.2457C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 1.0 pyrazinamide
clpC1 4038269 c.2434_2436delCCCinsGG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2431_2433delGGTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2395_2397delGTGinsAT frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 1.0 pyrazinamide
clpC1 4038491 c.2214C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038496 c.2209C>A synonymous_variant 1.0 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038575 c.2130C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038644 p.Glu687Asp missense_variant 0.98 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038650 c.2055C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039001 c.1704C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>A synonymous_variant 1.0 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039163 c.1540_1542delCTGinsAC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039199 c.1506C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039250 c.1455C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039258 p.Gln483Glu missense_variant 0.98 pyrazinamide
clpC1 4039259 c.1444_1446delGAGinsAC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039268 c.1437C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039336 c.1369C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039337 c.1368A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 0.98 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Ser missense_variant 0.98 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039581 p.Thr375Ser missense_variant 0.98 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039883 c.822G>A synonymous_variant 0.98 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.98 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039943 c.762G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039957 c.748C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039964 c.741C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040012 c.693G>A synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040033 c.672G>C synonymous_variant 0.99 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040093 c.612C>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040138 c.567G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040195 c.510G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040243 c.462C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040255 c.450C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040312 c.393G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.98 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.98 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.98 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.98 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.98 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>A synonymous_variant 0.98 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.98 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.77 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.73 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.93 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.96 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 0.96 pyrazinamide
clpC1 4040706 c.-4_-3delAC upstream_gene_variant 0.96 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.96 pyrazinamide
clpC1 4040728 c.-24G>T upstream_gene_variant 0.9 pyrazinamide Uncertain significance
panD 4044138 c.144T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 0.92 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 1.0 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 1.0 pyrazinamide
panD 4044174 c.108C>G synonymous_variant 1.0 pyrazinamide
panD 4044180 c.102C>T synonymous_variant 0.97 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.97 pyrazinamide
panD 4044210 c.72C>T synonymous_variant 0.98 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 0.97 pyrazinamide
panD 4044252 c.30C>T synonymous_variant 0.97 pyrazinamide
panD 4044261 c.21G>A synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
panD 4044276 p.Leu2Phe missense_variant 0.95 pyrazinamide
panD 4044287 c.-6A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044642 c.-361C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044647 c.-366C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044653 c.-372C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044659 c.-378G>A upstream_gene_variant 1.0 pyrazinamide
panD 4044662 c.-381C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044673 c.-392G>A upstream_gene_variant 1.0 pyrazinamide
panD 4044677 c.-396T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044686 c.-405C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044692 c.-411G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044695 c.-414C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044713 c.-432G>C upstream_gene_variant 0.97 pyrazinamide
panD 4044728 c.-447C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.98 pyrazinamide
panD 4044755 c.-474G>C upstream_gene_variant 0.98 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.97 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.94 pyrazinamide
panD 4044802 c.-521G>A upstream_gene_variant 0.95 pyrazinamide
panD 4044809 c.-528C>G upstream_gene_variant 0.95 pyrazinamide
panD 4044815 c.-534G>A upstream_gene_variant 0.95 pyrazinamide
panD 4044820 c.-539C>T upstream_gene_variant 0.94 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.86 pyrazinamide
panD 4044845 c.-566_-564delCCGinsGA upstream_gene_variant 0.85 pyrazinamide
panD 4044851 c.-570C>G upstream_gene_variant 0.89 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.89 pyrazinamide
panD 4044861 c.-580C>G upstream_gene_variant 0.89 pyrazinamide
panD 4044954 c.-673C>T upstream_gene_variant 0.94 pyrazinamide
panD 4044959 c.-678C>G upstream_gene_variant 0.95 pyrazinamide
panD 4044983 c.-702G>C upstream_gene_variant 0.95 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.91 pyrazinamide
panD 4044995 c.-714A>G upstream_gene_variant 0.91 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.91 pyrazinamide
panD 4045004 c.-723C>T upstream_gene_variant 0.91 pyrazinamide
panD 4045025 c.-744C>T upstream_gene_variant 0.9 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.9 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.9 pyrazinamide
panD 4045047 c.-766A>G upstream_gene_variant 0.8 pyrazinamide
glpK 4138411 c.1345C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138412 c.1344G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138415 c.1341G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138424 c.1332T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138429 c.1327T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138442 c.1314C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138451 c.1305T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138454 c.1302G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138472 c.1284G>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138490 c.1266G>T synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138495 p.Gln421Glu missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138500 p.Arg419His missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138519 p.Glu413Lys missense_variant 0.97 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138523 c.1233C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138564 c.1192C>T synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138652 c.1104G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138667 c.1089G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138696 p.Pro354Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138703 c.1053C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138727 c.1029C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138747 c.1009C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138751 c.1005T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 0.99 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138822 p.Asn312Asp missense_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138829 c.927A>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138838 c.918G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138841 c.915G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138847 c.909A>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138859 p.Asn299Lys missense_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138868 c.888G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138877 c.879A>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138880 c.876T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138889 c.867G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138895 c.861G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138898 c.858T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138907 c.849C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138910 c.846G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138913 c.843T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138934 c.820_822delCCAinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138943 c.813T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138946 c.810C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138949 c.807A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138964 c.792G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138973 c.783T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138976 c.780T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138982 c.774T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138985 c.771A>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139143 c.613T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139150 c.606G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139153 c.603C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139189 c.567G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139195 c.561G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139201 c.555C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139228 c.526_528delCCGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139231 c.525A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139242 c.514T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139243 c.513A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139249 c.507C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139253 p.Asn168Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139255 c.501G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139265 p.Ala164Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139270 c.486C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139273 c.483A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139276 c.480T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139285 p.Glu157Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139567 c.189C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139573 c.183C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139597 c.159C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139600 c.156G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139603 c.153C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139633 c.123C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139639 c.117G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139647 p.Ala37Thr missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139652 p.His35Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139657 c.99T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
embC 4238969 c.-894A>G upstream_gene_variant 1.0 ethambutol
embC 4238975 c.-888A>C upstream_gene_variant 0.95 ethambutol
embC 4238986 c.-877_-876delCAinsAG upstream_gene_variant 0.95 ethambutol
embC 4239014 c.-849C>G upstream_gene_variant 0.95 ethambutol
embC 4239018 c.-845C>T upstream_gene_variant 0.95 ethambutol
embC 4239026 c.-837G>C upstream_gene_variant 0.95 ethambutol
embC 4239027 c.-836A>G upstream_gene_variant 0.95 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 0.95 ethambutol Uncertain significance
embC 4239033 c.-830C>A upstream_gene_variant 0.95 ethambutol
embC 4239057 c.-806A>G upstream_gene_variant 1.0 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 1.0 ethambutol
embC 4239141 c.-722_-720delGCCinsAG upstream_gene_variant 0.94 ethambutol
embC 4239146 c.-717A>G upstream_gene_variant 0.94 ethambutol Uncertain significance
embC 4239147 c.-716_-714delTTGinsCA upstream_gene_variant 0.94 ethambutol
embC 4239152 c.-711G>C upstream_gene_variant 0.94 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 0.94 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 0.94 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 0.94 ethambutol
embC 4239185 c.-678G>C upstream_gene_variant 0.92 ethambutol
embC 4239189 c.-674C>T upstream_gene_variant 0.92 ethambutol
embC 4239193 c.-670G>C upstream_gene_variant 0.92 ethambutol
embC 4239326 c.-537C>T upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4239336 c.-527T>C upstream_gene_variant 0.92 ethambutol
embC 4239347 c.-516C>T upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4239378 c.-485T>C upstream_gene_variant 1.0 ethambutol
embC 4239395 c.-468C>T upstream_gene_variant 1.0 ethambutol
embC 4239398 c.-465G>T upstream_gene_variant 1.0 ethambutol
embC 4239401 c.-462A>C upstream_gene_variant 1.0 ethambutol
embC 4239408 c.-455G>A upstream_gene_variant 0.96 ethambutol Uncertain significance
embC 4239413 c.-450C>G upstream_gene_variant 0.95 ethambutol
embC 4239421 c.-442A>T upstream_gene_variant 0.95 ethambutol
embC 4239426 c.-437_-435delCCAinsGC upstream_gene_variant 0.94 ethambutol
embC 4239430 c.-433C>A upstream_gene_variant 0.94 ethambutol
embC 4239437 c.-426T>C upstream_gene_variant 0.96 ethambutol Uncertain significance
embC 4239443 c.-420C>G upstream_gene_variant 0.97 ethambutol
embC 4239448 c.-415G>T upstream_gene_variant 0.97 ethambutol
embC 4239466 c.-397_-396delGCinsCA upstream_gene_variant 0.97 ethambutol
embC 4239471 c.-392G>A upstream_gene_variant 0.97 ethambutol
embC 4239475 c.-388G>A upstream_gene_variant 0.97 ethambutol Uncertain significance
embC 4239482 c.-381C>G upstream_gene_variant 0.97 ethambutol
embC 4239483 c.-380G>C upstream_gene_variant 0.97 ethambutol
embC 4239486 c.-377T>A upstream_gene_variant 0.97 ethambutol
embC 4239512 c.-351G>C upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239533 c.-330T>C upstream_gene_variant 1.0 ethambutol
embC 4239539 c.-324G>A upstream_gene_variant 1.0 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 1.0 ethambutol
embC 4239703 c.-160G>A upstream_gene_variant 1.0 ethambutol
embC 4239710 c.-153C>G upstream_gene_variant 1.0 ethambutol
embC 4239723 c.-140C>G upstream_gene_variant 1.0 ethambutol
embC 4239749 c.-114T>C upstream_gene_variant 1.0 ethambutol
embC 4239752 c.-111T>G upstream_gene_variant 1.0 ethambutol
embC 4239764 c.-99G>C upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4239790 c.-73C>A upstream_gene_variant 0.8 ethambutol
embC 4240476 p.Ala205Gly missense_variant 1.0 ethambutol
embC 4240484 p.Ala208Thr missense_variant 1.0 ethambutol
embC 4240489 c.627A>G synonymous_variant 1.0 ethambutol
embC 4240495 c.633T>C synonymous_variant 1.0 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.82 ethambutol Not assoc w R
embC 4240678 c.816T>C synonymous_variant 0.86 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.9 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.94 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embC 4240717 c.855T>C synonymous_variant 0.96 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embC 4240777 c.915G>A synonymous_variant 0.99 ethambutol Not assoc w R - Interim
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240811 c.949_951delTTCinsCG frameshift_variant&missense_variant 0.96 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.95 ethambutol
embC 4240822 c.960C>G synonymous_variant 0.98 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.97 ethambutol
embC 4240834 c.972C>T synonymous_variant 0.97 ethambutol
embC 4240837 c.975C>G synonymous_variant 0.97 ethambutol
embC 4240843 c.981C>T synonymous_variant 0.94 ethambutol
embC 4240855 c.993G>C synonymous_variant 0.93 ethambutol
embC 4240858 c.996G>C synonymous_variant 0.91 ethambutol
embC 4240867 c.1005T>G synonymous_variant 0.93 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.86 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.8 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.92 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.93 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.97 ethambutol
embC 4241053 c.1191G>A synonymous_variant 0.97 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.97 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.98 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.97 ethambutol
embC 4241121 p.Ser420Asn missense_variant 1.0 ethambutol
embC 4241134 c.1272G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241164 c.1302G>A synonymous_variant 1.0 ethambutol
embC 4241167 c.1305C>G synonymous_variant 1.0 ethambutol
embC 4241170 c.1308G>C synonymous_variant 1.0 ethambutol
embC 4241182 c.1320G>C synonymous_variant 1.0 ethambutol
embC 4241185 c.1323G>C synonymous_variant 1.0 ethambutol
embC 4241191 c.1329C>T synonymous_variant 1.0 ethambutol
embC 4241194 c.1332C>G synonymous_variant 1.0 ethambutol
embC 4241197 c.1335G>C synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>C synonymous_variant 1.0 ethambutol
embC 4241206 c.1344G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241228 c.1366_1368delCTAinsTG frameshift_variant&stop_gained 1.0 ethambutol
embC 4241233 c.1371G>C synonymous_variant 1.0 ethambutol
embC 4241240 p.Leu460Val missense_variant 1.0 ethambutol
embC 4241245 c.1383C>T synonymous_variant 1.0 ethambutol
embC 4241248 c.1386G>C synonymous_variant 1.0 ethambutol
embC 4241251 c.1389T>A synonymous_variant 1.0 ethambutol
embC 4241256 p.Arg465Lys missense_variant 1.0 ethambutol
embC 4241268 p.Val469Ala missense_variant 1.0 ethambutol
embC 4241353 p.Ile497Met missense_variant 1.0 ethambutol Uncertain significance
embC 4241361 p.Asn500Thr missense_variant 1.0 ethambutol
embC 4241363 p.Leu501Ala missense_variant 1.0 ethambutol
embC 4241374 c.1512T>G synonymous_variant 1.0 ethambutol
embC 4241378 c.1516_1518delGTAinsCG frameshift_variant&missense_variant 1.0 ethambutol
embC 4241392 c.1530G>C synonymous_variant 1.0 ethambutol
embC 4241394 p.Lys511Ser missense_variant 1.0 ethambutol
embC 4241407 c.1545A>G synonymous_variant 1.0 ethambutol
embC 4241428 c.1566G>C synonymous_variant 1.0 ethambutol
embC 4241440 c.1578C>T synonymous_variant 1.0 ethambutol
embC 4241449 c.1587C>G synonymous_variant 1.0 ethambutol
embC 4241453 p.Ile531Val missense_variant 1.0 ethambutol
embC 4241458 c.1596C>G synonymous_variant 1.0 ethambutol
embC 4241788 c.1926C>T synonymous_variant 0.7 ethambutol
embC 4242104 p.Thr748Ser missense_variant 1.0 ethambutol
embC 4242112 c.2250G>C synonymous_variant 0.95 ethambutol
embC 4242121 c.2259A>G synonymous_variant 0.95 ethambutol
embC 4242124 c.2262C>T synonymous_variant 0.95 ethambutol
embC 4242127 c.2265G>A synonymous_variant 0.96 ethambutol
embC 4242133 c.2271G>C synonymous_variant 0.97 ethambutol
embC 4242138 p.Leu759Gln missense_variant 0.97 ethambutol
embC 4242143 p.Pro761Ala missense_variant 0.97 ethambutol
embC 4242151 c.2289A>C synonymous_variant 0.97 ethambutol
embC 4242172 c.2310C>G synonymous_variant 0.97 ethambutol
embC 4242174 p.Ala771Val missense_variant 0.97 ethambutol
embC 4242179 p.Leu773Val missense_variant 0.97 ethambutol
embC 4242193 c.2331G>C synonymous_variant 0.97 ethambutol
embC 4242202 c.2340C>A synonymous_variant 1.0 ethambutol
embC 4242203 c.2341C>T synonymous_variant 1.0 ethambutol
embC 4242208 c.2346T>A synonymous_variant 1.0 ethambutol
embC 4242214 c.2352C>G synonymous_variant 1.0 ethambutol
embC 4242220 c.2358A>G synonymous_variant 1.0 ethambutol
embC 4242229 c.2367C>T synonymous_variant 1.0 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.94 ethambutol
embA 4242826 c.-407G>T upstream_gene_variant 0.94 ethambutol
embA 4242829 c.-404G>C upstream_gene_variant 0.94 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 0.95 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.96 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.96 ethambutol
embA 4242847 c.-386C>T upstream_gene_variant 0.96 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.97 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 0.97 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.97 ethambutol
embA 4242868 c.-365C>T upstream_gene_variant 0.97 ethambutol
embA 4242880 c.-353A>G upstream_gene_variant 0.97 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embA 4242886 c.-347G>A upstream_gene_variant 0.97 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 1.0 ethambutol
embA 4242922 c.-311C>G upstream_gene_variant 1.0 ethambutol
embC 4242928 c.3066A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4243421 c.189A>G synonymous_variant 1.0 ethambutol
embA 4243427 c.195G>C synonymous_variant 0.95 ethambutol
embA 4243436 c.204C>G synonymous_variant 0.95 ethambutol
embA 4243439 c.207G>T synonymous_variant 0.95 ethambutol
embA 4243451 c.219G>C synonymous_variant 0.95 ethambutol
embA 4243461 p.Ser77Pro missense_variant 0.96 ethambutol Uncertain significance
embA 4243466 c.234C>G synonymous_variant 0.96 ethambutol
embA 4243476 c.244C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embA 4243485 p.Asn85Asp missense_variant 0.97 ethambutol
embA 4243505 c.273C>G synonymous_variant 0.96 ethambutol
embA 4243508 c.276A>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embA 4244045 c.813G>C synonymous_variant 0.92 ethambutol
embA 4244051 c.819T>C synonymous_variant 0.92 ethambutol
embA 4244057 c.825C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embA 4244061 p.Leu277Asn missense_variant 0.92 ethambutol
embA 4244070 p.Val280Ile missense_variant 0.85 ethambutol
embA 4244084 c.852C>G synonymous_variant 0.83 ethambutol
embA 4244099 c.867T>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embA 4244611 p.Ala460Gly missense_variant 0.93 ethambutol
embA 4244616 p.Ala462Ser missense_variant 0.94 ethambutol
embA 4244619 c.1387T>C synonymous_variant 0.94 ethambutol
embA 4244634 p.Val468Leu missense_variant 0.97 ethambutol
embA 4244645 c.1413T>C synonymous_variant 1.0 ethambutol
embA 4244648 c.1416G>C synonymous_variant 1.0 ethambutol
embA 4244649 p.Asp473Ser missense_variant 1.0 ethambutol
embA 4244654 c.1422G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244666 c.1434G>C synonymous_variant 1.0 ethambutol
embA 4244675 c.1443A>G synonymous_variant 1.0 ethambutol
embA 4244702 c.1470C>T synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embA 4244708 c.1476C>G synonymous_variant 0.97 ethambutol
embA 4244714 c.1482C>G synonymous_variant 0.97 ethambutol
embA 4244720 c.1488C>T synonymous_variant 0.96 ethambutol
embA 4244747 c.1515T>G synonymous_variant 0.93 ethambutol
embA 4244808 p.Phe526Leu missense_variant 1.0 ethambutol
embA 4244822 c.1590G>C synonymous_variant 1.0 ethambutol
embA 4244824 p.Val531Gly missense_variant 1.0 ethambutol
embA 4244829 c.1597_1599delTTCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244850 p.Arg540Gly missense_variant 1.0 ethambutol
embA 4244856 p.Ala542Pro missense_variant 0.96 ethambutol
embA 4244873 c.1641C>G synonymous_variant 0.96 ethambutol
embA 4244879 c.1647C>G synonymous_variant 0.93 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.95 ethambutol
embA 4244897 c.1665T>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 0.94 ethambutol
embA 4244921 c.1689C>G synonymous_variant 0.93 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.93 ethambutol
embA 4244936 c.1704C>G synonymous_variant 0.93 ethambutol
embA 4245041 c.1809C>G synonymous_variant 1.0 ethambutol
embA 4245053 c.1821G>C synonymous_variant 1.0 ethambutol
embA 4245060 c.1828T>C synonymous_variant 1.0 ethambutol
embA 4245083 c.1851A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245086 c.1854C>G synonymous_variant 1.0 ethambutol
embA 4245089 c.1857G>C synonymous_variant 1.0 ethambutol
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245136 p.Tyr635Phe missense_variant 0.98 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.98 ethambutol
embA 4245158 c.1926C>G synonymous_variant 0.98 ethambutol
embA 4245164 c.1932C>T synonymous_variant 0.98 ethambutol
embA 4245183 c.1951C>T synonymous_variant 0.98 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.98 ethambutol
embA 4245198 p.Leu656Phe missense_variant 1.0 ethambutol
embA 4245206 c.1974A>G synonymous_variant 1.0 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245218 c.1986C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4245224 c.1992T>C synonymous_variant 1.0 ethambutol
embA 4245233 c.2001G>C synonymous_variant 0.98 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.98 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embA 4245282 c.2050_2052delATCinsGG frameshift_variant&missense_variant 0.96 ethambutol Uncertain significance
embA 4245285 c.2053T>C synonymous_variant 0.96 ethambutol
embA 4245293 c.2061T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245296 c.2064G>C synonymous_variant 1.0 ethambutol
embA 4245299 c.2067A>G synonymous_variant 1.0 ethambutol
embA 4245315 p.Val695Thr missense_variant 1.0 ethambutol
embA 4245453 p.Ala741Thr missense_variant 1.0 ethambutol
embA 4245470 c.2238T>C synonymous_variant 1.0 ethambutol
embA 4245471 p.Ala747Ser missense_variant 1.0 ethambutol
embA 4245476 c.2244C>T synonymous_variant 1.0 ethambutol
embA 4245477 p.Met749Leu missense_variant 1.0 ethambutol
embA 4245497 c.2265C>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245500 c.2268G>A synonymous_variant 1.0 ethambutol
embA 4245501 c.2269_2271delGCGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245518 c.-996A>C upstream_gene_variant 1.0 ethambutol
embA 4245524 c.2292G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245527 c.-987C>T upstream_gene_variant 1.0 ethambutol
embB 4245530 c.-984T>G upstream_gene_variant 1.0 ethambutol
embA 4245535 p.Ser768Lys missense_variant 1.0 ethambutol
embA 4245569 p.Glu779Asp missense_variant 1.0 ethambutol
embB 4245575 c.-939C>G upstream_gene_variant 1.0 ethambutol
embA 4245576 p.Lys782Gln missense_variant 1.0 ethambutol
embB 4245593 c.-921C>G upstream_gene_variant 1.0 ethambutol
embB 4245594 c.-920_-919delTCinsAG upstream_gene_variant 1.0 ethambutol
embB 4245599 c.-915A>G upstream_gene_variant 1.0 ethambutol
embA 4245606 p.Leu792Val missense_variant 1.0 ethambutol
embB 4245611 c.-903C>G upstream_gene_variant 1.0 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 1.0 ethambutol
embA 4245623 c.2391G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245626 c.-888G>T upstream_gene_variant 1.0 ethambutol
embA 4245643 p.Ala804Val missense_variant 1.0 ethambutol
embA 4245648 p.Ile806Tyr missense_variant 1.0 ethambutol
embA 4245652 p.Thr807Ser missense_variant 1.0 ethambutol
embB 4245662 c.-852G>C upstream_gene_variant 1.0 ethambutol
embB 4245671 c.-843C>G upstream_gene_variant 1.0 ethambutol
embA 4245674 c.2442A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 1.0 ethambutol
embB 4245680 c.-834G>A upstream_gene_variant 1.0 ethambutol
embB 4245683 c.-831C>T upstream_gene_variant 1.0 ethambutol
embA 4245693 c.2461_2463delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245725 c.-789A>C upstream_gene_variant 1.0 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 1.0 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 1.0 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 1.0 ethambutol
embB 4245761 c.-753C>T upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embA 4245772 p.Asn847Thr missense_variant 1.0 ethambutol
embA 4245785 c.2553G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245791 c.-723C>G upstream_gene_variant 1.0 ethambutol
embA 4245795 c.2563_2565delGCCinsTG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245809 c.-705A>G upstream_gene_variant 1.0 ethambutol
embB 4245815 c.-699C>G upstream_gene_variant 1.0 ethambutol
embA 4245820 p.Ser863Thr missense_variant 1.0 ethambutol
embA 4245822 p.Pro864Gly missense_variant 0.94 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 1.0 ethambutol
embB 4245848 c.-666C>G upstream_gene_variant 1.0 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 1.0 ethambutol
embB 4245854 c.-660C>G upstream_gene_variant 1.0 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 1.0 ethambutol
embB 4245869 c.-645C>G upstream_gene_variant 1.0 ethambutol
embB 4245875 c.-639G>A upstream_gene_variant 1.0 ethambutol
embA 4246041 c.2809_2811delGACinsAT frameshift_variant&missense_variant 0.77 ethambutol Uncertain significance
embA 4246055 c.2823T>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embA 4246067 c.2835C>T synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4246079 c.-435C>T upstream_gene_variant 0.8 ethambutol
embA 4246080 c.2848_2850delCCTinsTC frameshift_variant&missense_variant 0.8 ethambutol Uncertain significance
embA 4246088 c.2856A>G synonymous_variant 0.94 ethambutol Not assoc w R
embB 4246097 c.-417C>G upstream_gene_variant 0.95 ethambutol
embA 4246103 c.2871C>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4246109 c.-405C>G upstream_gene_variant 0.92 ethambutol
embB 4246115 c.-399T>G upstream_gene_variant 0.96 ethambutol
embA 4246128 c.2896_2898delTCTinsAC frameshift_variant&missense_variant 0.95 ethambutol Uncertain significance
embA 4246138 p.Arg969Gln missense_variant 1.0 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 1.0 ethambutol
embB 4246148 c.-366G>A upstream_gene_variant 1.0 ethambutol
embA 4246151 c.2919A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4246152 p.Ala974Gln missense_variant 1.0 ethambutol
embB 4246157 c.-357A>G upstream_gene_variant 1.0 ethambutol
embB 4246178 c.-336G>C upstream_gene_variant 1.0 ethambutol
embB 4246184 c.-330A>C upstream_gene_variant 1.0 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.95 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.95 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.95 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 0.92 ethambutol
embA 4246329 p.Thr1033Leu missense_variant 0.93 ethambutol
embA 4246338 p.Leu1036Met missense_variant 0.97 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.96 ethambutol Uncertain significance
embB 4246364 c.-150G>C upstream_gene_variant 0.96 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.96 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.95 ethambutol
embB 4246385 c.-129T>C upstream_gene_variant 0.93 ethambutol
embB 4246794 p.Ala94Glu missense_variant 0.92 ethambutol
embB 4246804 c.291G>C synonymous_variant 0.94 ethambutol
embB 4246826 c.313_315delCAAinsAG frameshift_variant&missense_variant 0.96 ethambutol
embB 4246839 c.327_328insGCGCTC conservative_inframe_insertion 0.96 ethambutol
embB 4246843 c.331_336delTTGCAG conservative_inframe_deletion 0.96 ethambutol
embB 4246869 p.Ser119Asn missense_variant 0.92 ethambutol Uncertain significance
embB 4246872 p.Ala120Gly missense_variant 0.92 ethambutol
embB 4246882 c.369G>C synonymous_variant 0.92 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.88 ethambutol
embB 4247404 c.891G>C synonymous_variant 0.88 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.89 ethambutol
embB 4247425 c.912G>T synonymous_variant 0.94 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4247452 c.939C>G synonymous_variant 0.94 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.98 ethambutol
embB 4247476 c.963C>T synonymous_variant 0.98 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247528 c.1015C>T synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247550 p.Ala346Gly missense_variant 0.97 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>G synonymous_variant 1.0 ethambutol
embB 4247579 p.Ala356Ile missense_variant 0.92 ethambutol
embB 4247584 c.1071C>G synonymous_variant 0.92 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4247591 p.Val360Leu missense_variant 0.92 ethambutol Uncertain significance
embB 4247596 c.1083C>T synonymous_variant 0.92 ethambutol
embB 4247683 c.1170C>G synonymous_variant 0.92 ethambutol
embB 4247684 c.1171T>C synonymous_variant 0.92 ethambutol
embB 4247692 c.1179C>A synonymous_variant 0.95 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>A synonymous_variant 0.93 ethambutol
embB 4247842 c.1329T>G synonymous_variant 0.93 ethambutol
embB 4247854 c.1341C>T synonymous_variant 0.93 ethambutol
embB 4247857 c.1344C>G synonymous_variant 0.93 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.93 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247977 c.1464C>G synonymous_variant 1.0 ethambutol
embB 4247983 c.1470G>C synonymous_variant 1.0 ethambutol
embB 4248004 c.1491G>A synonymous_variant 0.97 ethambutol
embB 4248011 p.Ser500Ala missense_variant 0.97 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.98 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.98 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.98 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.98 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.99 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.99 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.99 ethambutol
embB 4248106 c.1593C>G synonymous_variant 1.0 ethambutol
embB 4248122 c.1609C>T synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248139 c.1626C>T synonymous_variant 0.99 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 1.0 ethambutol
embB 4248169 c.1656C>G synonymous_variant 1.0 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.99 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248211 c.1698G>C synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248252 p.Gly580Ala missense_variant 0.99 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>G synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>C synonymous_variant 1.0 ethambutol
embB 4248325 c.1812G>C synonymous_variant 1.0 ethambutol
embB 4248334 c.1821C>G synonymous_variant 0.97 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.95 ethambutol
embB 4248346 c.1833G>C synonymous_variant 0.95 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.95 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.95 ethambutol
embB 4248358 c.1845C>A synonymous_variant 0.95 ethambutol
embB 4248361 c.1848A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248368 c.1855C>T synonymous_variant 0.97 ethambutol
embB 4248403 c.1890G>C synonymous_variant 0.93 ethambutol
embB 4248406 c.1893G>C synonymous_variant 0.93 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 0.93 ethambutol
embB 4248410 c.1897_1899delTTCinsCG frameshift_variant&missense_variant 0.93 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.93 ethambutol
embB 4248430 c.1917T>C synonymous_variant 0.96 ethambutol
embB 4248432 p.Trp640Phe missense_variant 0.96 ethambutol
embB 4248448 c.1935C>T synonymous_variant 0.96 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.96 ethambutol
embB 4248463 c.1950C>G synonymous_variant 0.94 ethambutol
embB 4249111 c.2598T>C synonymous_variant 0.9 ethambutol
embB 4249129 c.2616T>C synonymous_variant 0.92 ethambutol
embB 4249147 c.2634C>G synonymous_variant 0.93 ethambutol
embB 4249168 c.2655C>A synonymous_variant 0.97 ethambutol
embB 4249174 c.2661C>T synonymous_variant 0.97 ethambutol
embB 4249177 c.2664G>C synonymous_variant 0.97 ethambutol
embB 4249187 c.2674_2676delTACinsCT frameshift_variant&missense_variant 0.96 ethambutol
embB 4249193 p.Pro894Thr missense_variant 0.96 ethambutol
embB 4249198 c.2685G>A synonymous_variant 0.96 ethambutol
embB 4249204 c.2691T>G synonymous_variant 0.96 ethambutol
embB 4249213 c.2700C>G synonymous_variant 1.0 ethambutol
embB 4249221 p.Ala903Gly missense_variant 1.0 ethambutol
embB 4249282 c.2769A>C synonymous_variant 0.93 ethambutol
embB 4249291 c.2778C>G synonymous_variant 0.95 ethambutol
embB 4249296 p.Ala928Val missense_variant 0.96 ethambutol
embB 4249321 c.2808A>G synonymous_variant 0.98 ethambutol
embB 4249322 c.2809_2811delGCAinsTG frameshift_variant&stop_gained 0.98 ethambutol
embB 4249325 p.Lys938Gln missense_variant 0.98 ethambutol
embB 4249338 p.Asp942Gly missense_variant 0.98 ethambutol
embB 4249342 c.2829C>G synonymous_variant 0.98 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.98 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.98 ethambutol
embB 4249423 p.Asp970Glu missense_variant 1.0 ethambutol Uncertain significance
embB 4249432 c.2919A>G synonymous_variant 1.0 ethambutol
embB 4249441 c.2928A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 1.0 ethambutol
embB 4249447 c.2934G>C synonymous_variant 0.96 ethambutol
embB 4249454 p.Thr981Ser missense_variant 1.0 ethambutol
embB 4249462 c.2949G>C synonymous_variant 1.0 ethambutol
embB 4249468 c.2955G>A synonymous_variant 1.0 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249487 c.2974_2976delTTGinsCT frameshift_variant&synonymous_variant 1.0 ethambutol
embB 4249498 c.2985G>C synonymous_variant 1.0 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.96 ethambutol
embB 4249525 c.3012T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 1.0 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4249546 c.3033G>A synonymous_variant 1.0 ethambutol
embB 4249552 c.3039C>G synonymous_variant 1.0 ethambutol
embB 4249558 c.3045A>C synonymous_variant 1.0 ethambutol
embB 4249568 p.Ser1019Thr missense_variant 1.0 ethambutol
embB 4249573 c.3060T>C synonymous_variant 1.0 ethambutol
embB 4249580 p.Leu1023Met missense_variant 1.0 ethambutol
embB 4249600 c.3087A>G synonymous_variant 1.0 ethambutol
embB 4249609 c.3096T>C synonymous_variant 1.0 ethambutol
embB 4249618 c.3105C>G synonymous_variant 1.0 ethambutol
embB 4249624 c.3111C>G synonymous_variant 1.0 ethambutol
embB 4249627 c.3114G>C synonymous_variant 1.0 ethambutol
embB 4249637 c.3124C>T synonymous_variant 1.0 ethambutol
embB 4249640 c.3127T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249657 c.3144C>G synonymous_variant 1.0 ethambutol
embB 4249661 p.Ala1050Ser missense_variant 1.0 ethambutol
aftB 4267483 c.1354T>C synonymous_variant 0.92 ethambutol
aftB 4267484 c.1353A>G synonymous_variant 0.93 ethambutol
aftB 4267496 p.Glu447Asp missense_variant 0.96 ethambutol
aftB 4267514 c.1323G>C synonymous_variant 0.97 ethambutol
aftB 4267517 c.1320A>C synonymous_variant 0.97 ethambutol
aftB 4267520 c.1317T>G synonymous_variant 0.97 ethambutol
aftB 4267523 c.1312_1314delGTGinsAC frameshift_variant&missense_variant 0.97 ethambutol Uncertain significance
aftB 4267535 c.1302A>G synonymous_variant 1.0 ethambutol
aftB 4267544 c.1293T>C synonymous_variant 1.0 ethambutol
aftB 4267547 c.1290C>G synonymous_variant 1.0 ethambutol
aftB 4267567 p.Leu424Val missense_variant 1.0 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 1.0 ethambutol
aftB 4267578 p.His420Arg missense_variant 1.0 ethambutol
aftB 4267592 c.1243_1245delGCCinsTG frameshift_variant&missense_variant 0.97 ethambutol Uncertain significance
aftB 4267595 c.1242C>T synonymous_variant 1.0 ethambutol
aftB 4267604 c.1233C>G synonymous_variant 1.0 ethambutol
aftB 4267634 p.Arg401His missense_variant 1.0 ethambutol
aftB 4267655 c.1182C>G synonymous_variant 1.0 ethambutol
aftB 4267658 c.1179G>C synonymous_variant 0.94 ethambutol
aftB 4267661 c.1176G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267670 c.1167G>A synonymous_variant 0.96 ethambutol
aftB 4267679 c.1158G>A synonymous_variant 0.95 ethambutol
aftB 4267685 c.1152T>C synonymous_variant 0.95 ethambutol
aftB 4267694 c.1143G>A synonymous_variant 0.92 ethambutol
aftB 4268138 c.699A>T synonymous_variant 1.0 ethambutol
aftB 4268144 c.693T>C synonymous_variant 1.0 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 1.0 ethambutol
aftB 4268955 c.-119A>G upstream_gene_variant 1.0 ethambutol
aftB 4268958 c.-122A>C upstream_gene_variant 1.0 ethambutol
aftB 4268964 c.-128G>C upstream_gene_variant 1.0 ethambutol
aftB 4268970 c.-134G>C upstream_gene_variant 1.0 ethambutol
aftB 4268975 c.-139C>T upstream_gene_variant 1.0 ethambutol
ubiA 4268984 c.850T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268985 c.-149A>G upstream_gene_variant 1.0 ethambutol
aftB 4269006 c.-170T>C upstream_gene_variant 1.0 ethambutol
aftB 4269027 c.-191C>G upstream_gene_variant 1.0 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 1.0 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 1.0 ethambutol
aftB 4269081 c.-245G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269089 p.Ala249Thr missense_variant 1.0 ethambutol Uncertain significance
aftB 4269123 c.-287T>G upstream_gene_variant 0.96 ethambutol
ubiA 4269143 p.Leu231Met missense_variant 0.97 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
ubiA 4269164 p.Leu224Met missense_variant 0.96 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.97 ethambutol
ubiA 4269209 p.Ser209Ala missense_variant 0.99 ethambutol
ubiA 4269221 p.Ala205Ser missense_variant 0.98 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.98 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 0.97 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.97 ethambutol
ethA 4326304 c.1170C>G synonymous_variant 0.75 ethionamide
ethA 4326307 c.1167C>G synonymous_variant 0.75 ethionamide
ethA 4326310 c.1164T>C synonymous_variant 0.75 ethionamide
ethA 4326319 c.1155C>A synonymous_variant 0.75 ethionamide
ethA 4326322 c.1152T>G synonymous_variant 0.75 ethionamide
ethA 4326332 p.Ala381Ile missense_variant 0.75 ethionamide
ethA 4326352 c.1122T>G synonymous_variant 0.75 ethionamide
ethR 4326847 c.-702G>C upstream_gene_variant 0.82 ethionamide
ethR 4326850 c.-699T>G upstream_gene_variant 0.83 ethionamide
ethR 4326853 c.-696G>C upstream_gene_variant 0.87 ethionamide
ethA 4326886 p.Asp196Glu missense_variant 0.97 ethionamide Uncertain significance
ethA 4326898 c.576G>C synonymous_variant 0.97 ethionamide Not assoc w R - Interim
ethR 4326904 c.-645G>C upstream_gene_variant 0.97 ethionamide
ethR 4326907 c.-642C>G upstream_gene_variant 0.97 ethionamide
ethR 4326916 c.-633C>G upstream_gene_variant 0.97 ethionamide
ethR 4326919 c.-630T>G upstream_gene_variant 0.97 ethionamide
ethR 4326934 c.-615C>G upstream_gene_variant 0.97 ethionamide
ethA 4326949 p.Ala175Gly missense_variant 0.95 ethionamide
ethA 4326953 p.Asp174Ala missense_variant 0.95 ethionamide
ethR 4326985 c.-564A>G upstream_gene_variant 1.0 ethionamide
ethA 4326997 c.477G>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
ethA 4327001 p.Val158Thr missense_variant 1.0 ethionamide
ethR 4327006 c.-543A>G upstream_gene_variant 1.0 ethionamide
ethR 4327009 c.-540C>T upstream_gene_variant 0.93 ethionamide
ethA 4327018 p.Ala152Glu missense_variant 0.92 ethionamide
ethR 4327021 c.-528G>A upstream_gene_variant 0.92 ethionamide
ethR 4327024 c.-525T>C upstream_gene_variant 0.92 ethionamide
ethA 4327032 p.Ser148Ala missense_variant 0.92 ethionamide
ethA 4327041 p.Glu145Gln missense_variant 0.92 ethionamide
ethA 4327042 p.Asp144Glu missense_variant 0.92 ethionamide
ethR 4327303 c.-246G>C upstream_gene_variant 0.89 ethionamide
ethR 4327312 c.-237G>A upstream_gene_variant 0.9 ethionamide
ethR 4327321 c.-228G>C upstream_gene_variant 0.91 ethionamide
ethR 4327324 c.-225A>G upstream_gene_variant 0.91 ethionamide
ethR 4327327 c.-222A>G upstream_gene_variant 0.91 ethionamide
ethR 4327335 c.-214A>G upstream_gene_variant 0.91 ethionamide
ethR 4327336 c.-213A>G upstream_gene_variant 0.92 ethionamide
ethR 4327342 c.-207G>C upstream_gene_variant 0.93 ethionamide
ethA 4327356 p.Ser40Ala missense_variant 0.95 ethionamide
ethA 4327357 p.Glu39Ala missense_variant 0.95 ethionamide
ethR 4327396 c.-153A>G upstream_gene_variant 0.97 ethionamide
ethR 4327414 c.-135G>C upstream_gene_variant 1.0 ethionamide
ethR 4327420 c.-129G>A upstream_gene_variant 1.0 ethionamide
ethR 4327423 c.-126G>C upstream_gene_variant 1.0 ethionamide
ethR 4327426 c.-123A>G upstream_gene_variant 1.0 ethionamide
ethR 4327438 c.-111A>G upstream_gene_variant 1.0 ethionamide
ethR 4327453 c.-96A>G upstream_gene_variant 1.0 ethionamide