TB-Profiler result

Run: ERR3445503
Summary

Run ID: ERR3445503

Sample name:

Date: 2024-04-16T07:07:06.299320

Number of reads: 782993

Percentage reads mapped: 15.19

Median coverage: 10.0

Strain: La1.7.1;La1.7.X-unk4

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.7 M.bovis None 0.33
La1.7.1 M.bovis None 0.07
La1.7.X-unk4 M.bovis None 1.0
La1 M.bovis None 0.32
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Asp311Gly Mutation from literature
pyrazinamide pncA p.His57Asp Assoc w R
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.820_822delTTAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1120_1122delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1189_1191delAAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.62 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsAC frameshift_variant&missense_variant 0.58 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.65 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304050 c.1120_1122delTTGinsCC frameshift_variant&missense_variant 0.72 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304119 c.1189_1191delAAAinsCG frameshift_variant&missense_variant 0.61 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide Assoc w R
embB 4247445 p.Asp311Gly missense_variant 0.38 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 0.5 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.53 isoniazid
dnaA 714 c.714C>G synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.82 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.82 isoniazid
dnaA 765 c.766_767insCG frameshift_variant 0.82 isoniazid Uncertain significance
dnaA 769 c.770_771delCA frameshift_variant 0.83 isoniazid Uncertain significance
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.82 isoniazid Uncertain significance
dnaA 802 c.802C>T synonymous_variant 0.82 isoniazid
dnaA 805 c.805T>C synonymous_variant 0.81 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.8 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.8 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.8 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.83 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.82 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 864 c.864C>T synonymous_variant 0.83 isoniazid
dnaA 876 c.876C>A synonymous_variant 0.8 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.81 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.83 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.85 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.86 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.86 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.85 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.86 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.86 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.88 isoniazid
dnaA 955 c.955_957delAGAinsCC frameshift_variant&missense_variant 0.86 isoniazid Uncertain significance
dnaA 960 c.960C>T synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 966 c.966T>C synonymous_variant 0.88 isoniazid
dnaA 975 c.975G>A synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.85 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.85 isoniazid
dnaA 999 c.999C>G synonymous_variant 0.86 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.86 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.82 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.81 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 0.8 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.77 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 0.77 isoniazid
dnaA 1047 p.Glu349Asp missense_variant 0.75 isoniazid
dnaA 1050 c.1050G>T synonymous_variant 0.75 isoniazid
dnaA 1055 p.Ala352Asp missense_variant 0.73 isoniazid
dnaA 1059 c.1059C>T synonymous_variant 0.74 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.79 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.8 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.8 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.79 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.81 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 0.81 isoniazid
dnaA 1134 c.1134G>C synonymous_variant 0.82 isoniazid
dnaA 1140 c.1140C>G synonymous_variant 0.79 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.8 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.82 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.77 isoniazid
dnaA 1165 c.1165_1167delCCAinsGG frameshift_variant&missense_variant 0.78 isoniazid Uncertain significance
dnaA 1176 c.1176A>G synonymous_variant 0.77 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.77 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.74 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.74 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 0.74 isoniazid
dnaA 1210 p.Ala404Ser missense_variant 0.73 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.65 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.64 isoniazid
dnaA 1237 c.1237_1239delGCGinsAC frameshift_variant&missense_variant 0.55 isoniazid Uncertain significance
dnaA 1254 c.1254T>G synonymous_variant 0.59 isoniazid
gyrB 6127 c.888G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6202 c.963C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6203 p.Ser322Ala missense_variant 0.71 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.67 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6316 c.-986G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6325 c.-977C>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6326 c.-976_-975delAGinsTC upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6334 c.-968G>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 0.83 levofloxacin Uncertain significance
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 6398 p.Val387Ile missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6490 c.-812T>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6511 c.-791A>T upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 6532 c.-770C>T upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6556 c.-746C>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6631 c.-671C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.68 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.69 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6896 p.Arg553Lys missense_variant 0.38 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>T upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 6905 c.1666_1668delATCinsGG frameshift_variant&missense_variant 0.32 levofloxacin Uncertain significance
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6920 c.1681_1683delGTGinsAC frameshift_variant&missense_variant 0.33 levofloxacin Uncertain significance
moxifloxacin
gyrA 6925 c.-377T>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6931 c.-371A>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6997 c.-305G>A upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7015 c.-287G>A upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Arg missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>A upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrB 7047 p.Lys603Thr missense_variant 0.75 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.76 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7114 c.-188C>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>T upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>A upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7216 c.-86G>T upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7237 c.-65C>T upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7415 c.114C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7448 c.147G>A synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7484 c.183T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7490 c.189C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.84 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7775 c.474C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7862 c.561C>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8147 c.846C>T synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8190 p.Ala297Asn missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 8240 c.939C>A synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCT frameshift_variant&missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8312 c.1011G>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8357 c.1056G>T synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8367 c.1066C>T synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8400 p.Asp367Asn missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8477 c.1176C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8547 c.1246_1248delATCinsGG frameshift_variant&missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Gln missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8562 c.1261C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 p.Glu429Asp missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8708 c.1407G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8720 c.1419G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8796 c.1495_1497delATCinsGG frameshift_variant&missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.65 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8817 p.Ser506Ala missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8951 c.1650G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8954 c.1653G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9104 c.1803C>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9134 c.1833C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9161 c.1860C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9197 c.1896G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9207 p.Lys636Arg missense_variant 0.62 levofloxacin
moxifloxacin
gyrA 9213 p.Thr638Val missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9284 c.1983T>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9314 c.2013G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9332 p.Asn677Lys missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9369 c.2068C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9383 c.2082T>G synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9389 c.2088C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 9425 c.2124C>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Ala missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 9446 c.2145C>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9453 c.2154_2158delTGAAG frameshift_variant 0.55 levofloxacin
moxifloxacin
gyrA 9461 c.2160_2161insCCGAT frameshift_variant 0.5 levofloxacin
moxifloxacin
gyrA 9464 c.2163C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9467 c.2166T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9485 c.2184A>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>T synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 9500 c.2199A>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9503 c.2202T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 9515 p.Glu738Asp missense_variant 0.52 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9518 c.2217A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.48 levofloxacin
moxifloxacin
fgd1 491034 c.252C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491037 c.255C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491055 c.273C>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 0.58 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491073 c.291C>T synonymous_variant 0.6 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491082 c.300T>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 491139 c.357G>A synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>T synonymous_variant 0.79 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491144 p.Ala121Asp missense_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491172 c.390C>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491491 p.Pro237Thr missense_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491605 c.823C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491652 c.870C>A synonymous_variant 0.67 clofazimine
pretomanid
delamanid
mshA 575548 c.201C>A synonymous_variant 0.68 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.74 ethionamide
isoniazid
mshA 575566 c.219G>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575581 p.His78Gln missense_variant 0.74 ethionamide
isoniazid
mshA 575582 p.Leu79Met missense_variant 0.75 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.72 ethionamide
isoniazid
mshA 575597 p.Ile84Val missense_variant 0.74 ethionamide
isoniazid
mshA 575620 c.273G>T synonymous_variant 0.69 ethionamide
isoniazid
mshA 575623 c.276C>A synonymous_variant 0.71 ethionamide
isoniazid
mshA 575626 c.279C>G synonymous_variant 0.71 ethionamide
isoniazid
mshA 575627 c.280_282delGCAinsTG frameshift_variant&stop_gained 0.71 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575635 c.288A>C synonymous_variant 0.69 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 0.69 ethionamide
isoniazid
mshA 575640 p.Pro98Gln missense_variant 0.69 ethionamide
isoniazid
mshA 575645 c.298_300delGTGinsAC frameshift_variant&missense_variant 0.68 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575656 c.309G>C synonymous_variant 0.68 ethionamide
isoniazid
mshA 575665 c.318G>T synonymous_variant 0.71 ethionamide
isoniazid Not assoc w R - Interim
mshA 575686 c.339G>T synonymous_variant 0.7 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 0.7 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.7 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>G synonymous_variant 0.65 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 0.63 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575713 c.366G>A synonymous_variant 0.68 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.73 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.72 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.74 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.74 ethionamide
isoniazid
mshA 575761 c.414C>G synonymous_variant 0.74 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.74 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.73 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.73 ethionamide
isoniazid Not assoc w R - Interim
mshA 575821 c.474G>C synonymous_variant 0.76 ethionamide
isoniazid
mshA 575839 c.492G>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.78 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.76 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.76 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575908 c.561A>T synonymous_variant 0.71 ethionamide
isoniazid
mshA 575911 c.564G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 575917 p.Asp190Glu missense_variant 0.69 ethionamide
isoniazid
mshA 575924 p.Gly193Ser missense_variant 0.7 ethionamide
isoniazid
mshA 575935 c.588G>T synonymous_variant 0.73 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.66 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 0.66 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 0.67 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.64 ethionamide
isoniazid Not assoc w R - Interim
ccsA 620307 c.417C>G synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620311 p.Leu141Val missense_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620316 c.426G>C synonymous_variant 0.75 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620319 c.429C>T synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620325 c.435G>T synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620352 c.462C>T synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>A synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.81 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620430 c.540C>T synonymous_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620569 p.Gly227Arg missense_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620589 c.699G>A synonymous_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620709 c.819G>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>A synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 620725 c.835C>T synonymous_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>T synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620754 c.864G>A synonymous_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620758 p.Arg290Lys missense_variant 0.68 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>G synonymous_variant 0.68 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620791 c.901_903delGTGinsAC frameshift_variant&missense_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620802 c.912C>G synonymous_variant 0.57 capreomycin
amikacin
kanamycin
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
hadA 731753 c.-177A>T upstream_gene_variant 0.57 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.62 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.67 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.57 isoniazid
nusG 734384 p.Ser44Thr missense_variant 0.33 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.58 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.67 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.69 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.74 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.78 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.8 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.8 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.79 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.83 rifampicin
nusG 734508 c.255C>G synonymous_variant 0.83 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.71 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>C synonymous_variant 0.54 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.46 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.5 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.5 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.5 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.5 rifampicin
nusG 734863 p.Thr204Ser missense_variant 0.5 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.5 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.7 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.7 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.72 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.76 rifampicin Uncertain significance
rpoB 760139 c.333A>C synonymous_variant 0.79 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.8 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.94 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.94 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.93 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.93 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.89 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.89 rifampicin
rpoB 760357 p.Thr184Asn missense_variant 0.92 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.92 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.91 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.9 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.87 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 0.86 rifampicin
rpoB 760514 c.708C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.87 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.87 rifampicin
rpoB 760541 c.735G>T synonymous_variant 0.89 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.9 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.93 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.95 rifampicin
rpoB 760629 c.823C>T synonymous_variant 0.94 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760674 c.868T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.71 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.74 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.86 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.87 rifampicin
rpoB 761124 c.1318C>T synonymous_variant 0.83 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.93 rifampicin
rpoB 761217 c.1411_1413delCCGinsGC frameshift_variant&missense_variant 0.9 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.95 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 0.93 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761342 c.1536G>A synonymous_variant 0.89 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.87 rifampicin
rpoB 761346 p.Val514Lys missense_variant 0.87 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.87 rifampicin
rpoB 761357 c.1551G>T synonymous_variant 0.87 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.87 rifampicin
rpoB 761369 p.Glu521Asp missense_variant 0.88 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.84 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.85 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.75 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.7 rifampicin
rpoB 761437 p.Ala544Glu missense_variant 0.68 rifampicin
rpoB 761439 p.Asp545Asn missense_variant 0.7 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.7 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.72 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.85 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.91 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.91 rifampicin
rpoB 761661 c.1855C>T synonymous_variant 0.9 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.87 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.87 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.89 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.83 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.77 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.66 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.66 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.65 rifampicin
rpoB 761786 c.1980C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761791 p.Arg662His missense_variant 0.69 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.76 rifampicin
rpoB 761816 c.2010C>G synonymous_variant 0.76 rifampicin
rpoB 761819 c.2013G>T synonymous_variant 0.74 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.78 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.78 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.78 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.8 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 0.8 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 0.82 rifampicin
rpoB 761882 c.2076C>G synonymous_variant 0.85 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.89 rifampicin
rpoB 761903 c.2097T>G synonymous_variant 0.88 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.88 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.87 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.88 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.88 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.88 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.88 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>A synonymous_variant 0.9 rifampicin
rpoB 761999 c.2193G>C synonymous_variant 0.95 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.98 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.98 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.97 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.97 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.97 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 0.89 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.9 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 0.86 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.8 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 0.81 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.78 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.62 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.61 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.61 rifampicin
rpoB 762348 c.2542_2543delTCinsAG synonymous_variant 0.61 rifampicin
rpoB 762359 c.2553C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 0.62 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.62 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.65 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.68 rifampicin
rpoC 762390 c.-980C>T upstream_gene_variant 0.65 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.65 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.65 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.65 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.68 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.85 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 762503 c.-867G>C upstream_gene_variant 0.86 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.86 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.86 rifampicin Uncertain significance
rpoC 762533 c.-837T>C upstream_gene_variant 0.86 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.86 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.86 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.91 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.91 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.9 rifampicin
rpoC 762575 c.-795C>T upstream_gene_variant 0.85 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.82 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.81 rifampicin
rpoB 762595 c.2789_2790insC frameshift_variant 0.64 rifampicin
rpoB 762600 p.Trp932Gly missense_variant 0.54 rifampicin
rpoB 762604 c.2799delT frameshift_variant 0.59 rifampicin
rpoB 762609 c.2803_2805delCACinsAG frameshift_variant&missense_variant 0.59 rifampicin
rpoB 762725 c.2919C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762730 p.Gln975Arg missense_variant 0.72 rifampicin
rpoC 762734 c.-636G>A upstream_gene_variant 0.68 rifampicin
rpoC 762737 c.-633C>G upstream_gene_variant 0.67 rifampicin
rpoB 762749 c.2943C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762753 c.2947_2949delTTGinsCC frameshift_variant&missense_variant 0.69 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 0.73 rifampicin Uncertain significance
rpoB 762782 c.2976T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.78 rifampicin Uncertain significance
rpoB 762786 p.Val994Thr missense_variant 0.78 rifampicin
rpoC 762791 c.-579G>C upstream_gene_variant 0.79 rifampicin
rpoB 762799 p.Ala998Glu missense_variant 0.81 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762818 c.3012C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 762827 c.-543G>T upstream_gene_variant 0.85 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 762851 c.-519C>T upstream_gene_variant 0.86 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 762863 c.-507T>G upstream_gene_variant 0.83 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.86 rifampicin Uncertain significance
rpoC 762917 c.-453C>T upstream_gene_variant 0.9 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.75 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.74 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.72 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763172 c.-198G>T upstream_gene_variant 0.69 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>A synonymous_variant 0.71 rifampicin
rpoC 763411 c.42T>C synonymous_variant 0.71 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.71 rifampicin
rpoC 763420 c.51G>C synonymous_variant 0.73 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.73 rifampicin Uncertain significance
rpoC 763429 c.60C>T synonymous_variant 0.77 rifampicin
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.75 rifampicin
rpoC 763435 c.66A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.88 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763648 c.279C>T synonymous_variant 0.92 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 0.94 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.94 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.94 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.92 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.92 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.9 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.9 rifampicin
rpoC 763781 c.412_414delTCGinsGC frameshift_variant&missense_variant 0.88 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.89 rifampicin
rpoC 763801 c.432C>T synonymous_variant 0.87 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.84 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.83 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.81 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.72 rifampicin
rpoC 763925 p.Ala186Lys missense_variant 0.74 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.74 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 0.71 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.71 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.74 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763972 c.603C>T synonymous_variant 0.8 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.88 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.86 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.86 rifampicin
rpoC 764015 c.646C>T synonymous_variant 0.87 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.85 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.87 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.89 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.89 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.89 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.87 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.87 rifampicin
rpoC 764095 c.726C>G synonymous_variant 0.86 rifampicin
rpoC 764101 c.732C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.84 rifampicin
rpoC 764134 c.765C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764147 c.778_780delTCGinsGC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.9 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.87 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.86 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764194 c.825G>A synonymous_variant 0.84 rifampicin
rpoC 764195 p.Ser276Glu missense_variant 0.84 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.84 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.86 rifampicin
rpoC 764239 c.870T>C synonymous_variant 0.89 rifampicin
rpoC 764245 c.876C>G synonymous_variant 0.89 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.91 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.89 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.88 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764285 p.Gly306Ser missense_variant 0.89 rifampicin
rpoC 764293 c.924G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.89 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.9 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.88 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 764392 c.1023C>T synonymous_variant 0.88 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.93 rifampicin
rpoC 764425 c.1056C>T synonymous_variant 0.91 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.91 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.93 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.95 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.92 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.93 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.97 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.95 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.95 rifampicin
rpoC 764573 c.1204_1206delCTTinsTG frameshift_variant&missense_variant 0.89 rifampicin
rpoC 764578 c.1209C>G synonymous_variant 0.91 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 0.86 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.91 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.91 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.91 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.91 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.92 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.94 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.94 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.94 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.93 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.93 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764926 c.1557C>T synonymous_variant 0.91 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.91 rifampicin
rpoC 764956 c.1587T>C synonymous_variant 0.91 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>T synonymous_variant 0.89 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.89 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.89 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.85 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.84 rifampicin
rpoC 765085 c.1716T>G synonymous_variant 0.85 rifampicin
rpoC 765121 c.1752G>C synonymous_variant 0.67 rifampicin
rpoC 765382 c.2013G>C synonymous_variant 0.81 rifampicin
rpoC 765397 c.2028G>T synonymous_variant 0.89 rifampicin
rpoC 765405 p.Leu679His missense_variant 0.89 rifampicin Uncertain significance
rpoC 765409 c.2040T>A synonymous_variant 0.87 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.87 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.9 rifampicin
rpoC 765452 p.Ala695Arg missense_variant 0.9 rifampicin
rpoC 765458 p.Ile697Val missense_variant 0.9 rifampicin Uncertain significance
rpoC 765466 c.2097C>T synonymous_variant 0.9 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.94 rifampicin Uncertain significance
rpoC 765496 c.2127C>T synonymous_variant 0.94 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765505 c.2136C>A synonymous_variant 0.96 rifampicin
rpoC 765508 c.2139C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765718 p.Asp783Glu missense_variant 0.41 rifampicin Uncertain significance
rpoC 765727 c.2358T>C synonymous_variant 0.41 rifampicin
rpoC 765728 p.Gln787Glu missense_variant 0.41 rifampicin
rpoC 765733 c.2364G>C synonymous_variant 0.47 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765741 p.Glu791Ala missense_variant 0.55 rifampicin Uncertain significance
rpoC 765751 c.2382C>G synonymous_variant 0.61 rifampicin
rpoC 765752 c.2383_2385delGACinsAG frameshift_variant&missense_variant 0.68 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.82 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.83 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.84 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.84 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.84 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.83 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765812 c.2443_2445delCGAinsAG frameshift_variant&synonymous_variant 0.81 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.78 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.86 rifampicin Uncertain significance
rpoC 765883 c.2514C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 0.86 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765913 c.2544G>A synonymous_variant 0.91 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.92 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 0.91 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.92 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765970 c.2601C>G synonymous_variant 0.97 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 0.91 rifampicin
rpoC 766012 c.2643C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.89 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 0.88 rifampicin
rpoC 766034 p.His889Thr missense_variant 0.82 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.76 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 0.67 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.67 rifampicin
rpoC 766324 c.2955C>G synonymous_variant 0.7 rifampicin
rpoC 766333 c.2964G>C synonymous_variant 0.75 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.82 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.82 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.82 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.82 rifampicin
rpoC 766375 c.3006C>G synonymous_variant 0.83 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.82 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.82 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.82 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.86 rifampicin
rpoC 766423 c.3054T>C synonymous_variant 0.88 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 0.91 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 0.88 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.87 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 0.88 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 0.87 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.88 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.88 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.88 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.86 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.85 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.79 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766720 c.3351C>T synonymous_variant 0.91 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.91 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.93 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.93 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.93 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.93 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.93 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.91 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.86 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.82 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.81 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.83 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.81 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.81 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766920 p.Ala1184Gly missense_variant 0.81 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 0.83 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766951 c.3582G>C synonymous_variant 0.93 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766975 c.3606C>G synonymous_variant 0.92 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 0.93 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767041 c.3672G>C synonymous_variant 0.94 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>C synonymous_variant 0.92 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.87 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.89 rifampicin
rpoC 767146 c.3777G>A synonymous_variant 0.9 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.89 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.9 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.91 rifampicin
rpoC 767203 c.3834C>A synonymous_variant 0.9 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.71 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.71 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 767288 c.3919C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
mmpL5 777115 p.Met456Leu missense_variant 0.58 clofazimine
bedaquiline
mmpL5 777122 c.1359C>T synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 777142 p.Val447Leu missense_variant 0.73 clofazimine
bedaquiline
mmpL5 777164 c.1317C>A synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.63 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777194 c.1285_1287delGAAinsCG frameshift_variant&missense_variant 0.63 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777203 c.1278G>T synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 777209 c.1272C>T synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 777227 c.1254C>G synonymous_variant 0.58 clofazimine
bedaquiline
mmpL5 777245 c.1236G>C synonymous_variant 0.58 clofazimine
bedaquiline
mmpL5 777254 c.1227G>C synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 777262 p.Thr407Ala missense_variant 0.6 clofazimine
bedaquiline
mmpL5 777488 c.993C>T synonymous_variant 0.55 clofazimine
bedaquiline
mmpL5 777491 c.990G>C synonymous_variant 0.55 clofazimine
bedaquiline
mmpL5 777497 c.984A>G synonymous_variant 0.58 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777519 p.Thr321Leu missense_variant 0.6 clofazimine
bedaquiline
mmpL5 777521 c.960C>G synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777524 c.957T>C synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777527 c.954G>C synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777533 c.948C>G synonymous_variant 0.59 clofazimine
bedaquiline
mmpL5 777539 c.942T>C synonymous_variant 0.57 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.82 streptomycin
rpsL 781597 p.Arg13His missense_variant 0.82 streptomycin
rpsL 781605 p.Ile16Pro missense_variant 0.78 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.78 streptomycin
rpsL 781615 p.Val19Ala missense_variant 0.78 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.81 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.79 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.8 streptomycin
rpsL 781652 c.93T>C synonymous_variant 0.8 streptomycin
rpsL 781655 c.96T>A synonymous_variant 0.79 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.82 streptomycin
rpsL 781676 c.117C>G synonymous_variant 0.82 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.83 streptomycin
rpsL 781703 c.144G>A synonymous_variant 0.82 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.78 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.78 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.78 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.78 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.78 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.78 streptomycin
rpsL 781737 p.Gln60Ala missense_variant 0.78 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.82 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.82 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.81 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.84 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.81 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.81 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.78 streptomycin Not assoc w R - Interim
rpsL 781862 c.303G>C synonymous_variant 0.79 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.81 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.81 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.82 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.83 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.81 streptomycin
rpsL 781898 c.339A>G synonymous_variant 0.8 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.8 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.78 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.83 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.83 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.82 linezolid
rplC 800537 c.-272C>G upstream_gene_variant 0.8 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.81 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.85 linezolid
rplC 800564 c.-245C>G upstream_gene_variant 0.87 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.86 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.86 linezolid
rplC 800577 c.-232_-230delCGCinsAA upstream_gene_variant 0.86 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.87 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.87 linezolid
rplC 800597 c.-212A>T upstream_gene_variant 0.87 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.87 linezolid
rplC 800603 c.-206G>T upstream_gene_variant 0.87 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.9 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.88 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.87 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.87 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.87 linezolid
rplC 800693 c.-116A>T upstream_gene_variant 0.88 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.88 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.88 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.88 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.88 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 0.83 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.83 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.82 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.81 linezolid
rplC 800829 c.21C>G synonymous_variant 0.75 linezolid
rplC 800832 c.24T>C synonymous_variant 0.76 linezolid
rplC 800844 c.36T>C synonymous_variant 0.84 linezolid
rplC 800856 c.48A>G synonymous_variant 0.88 linezolid
rplC 800865 c.57A>G synonymous_variant 0.88 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.88 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.83 linezolid
rplC 800877 c.69A>C synonymous_variant 0.85 linezolid
rplC 800880 c.72A>G synonymous_variant 0.86 linezolid
rplC 800889 c.81C>G synonymous_variant 0.88 linezolid
rplC 800892 c.84G>C synonymous_variant 0.88 linezolid
rplC 800916 c.108A>G synonymous_variant 0.88 linezolid
rplC 800919 c.111C>G synonymous_variant 0.88 linezolid
rplC 800934 c.126C>G synonymous_variant 0.88 linezolid
rplC 800937 c.129A>G synonymous_variant 0.88 linezolid
rplC 800946 c.138T>G synonymous_variant 0.83 linezolid
rplC 800949 c.141T>C synonymous_variant 0.81 linezolid
rplC 800955 c.147C>T synonymous_variant 0.86 linezolid
rplC 800961 c.153G>A synonymous_variant 0.85 linezolid
rplC 800970 c.162T>C synonymous_variant 0.83 linezolid Not assoc w R - Interim
rplC 800985 c.177A>C synonymous_variant 0.67 linezolid
rplC 800988 c.180C>G synonymous_variant 0.67 linezolid
rplC 801171 c.363A>G synonymous_variant 0.5 linezolid
rplC 801186 c.378C>G synonymous_variant 0.79 linezolid
rplC 801222 c.414T>C synonymous_variant 0.78 linezolid
rplC 801228 c.420T>C synonymous_variant 0.81 linezolid
rplC 801231 c.423C>G synonymous_variant 0.78 linezolid
rplC 801237 c.429G>T synonymous_variant 0.82 linezolid
rplC 801249 c.441T>C synonymous_variant 0.84 linezolid
rplC 801252 c.444G>C synonymous_variant 0.82 linezolid
rplC 801264 c.456C>T synonymous_variant 0.79 linezolid
rplC 801267 c.459A>C synonymous_variant 0.78 linezolid
rplC 801270 c.462T>C synonymous_variant 0.77 linezolid
rplC 801276 c.468G>A synonymous_variant 0.74 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.75 linezolid
rplC 801300 c.492C>G synonymous_variant 0.69 linezolid
rplC 801303 c.495G>T synonymous_variant 0.69 linezolid
rplC 801307 c.499_501delGCCinsTG frameshift_variant&missense_variant 0.67 linezolid
rplC 801312 c.504G>C synonymous_variant 0.67 linezolid
rplC 801315 c.507G>T synonymous_variant 0.67 linezolid
rplC 801330 c.522G>C synonymous_variant 0.59 linezolid
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiC 1303686 c.756C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303701 c.771C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303713 c.783C>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268His missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303746 p.Asp272Glu missense_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303755 c.825T>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303765 p.Lys279Arg missense_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>A synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1304059 c.1129C>T synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304070 c.1140C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304079 p.Glu383Asp missense_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304106 c.1176G>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>C synonymous_variant 0.63 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.84 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304761 p.Val611Ile missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304961 c.2031C>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304967 c.2037G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305043 c.2113_2115delTCAinsAGT synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305073 p.Ser715Gln missense_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305100 p.Asn724Arg missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1305106 c.2176C>T synonymous_variant 0.62 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305114 p.Asp728Glu missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.65 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305129 c.2199C>A synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305135 c.2205C>T synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>A synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305168 c.2238C>T synonymous_variant 0.47 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305173 p.Asn748Ser missense_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
sigE 1364658 c.246G>C synonymous_variant 0.44 pyrazinamide
sigE 1364661 c.249C>G synonymous_variant 0.44 pyrazinamide
sigE 1364673 c.261G>C synonymous_variant 0.65 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.65 pyrazinamide
sigE 1364679 c.267T>C synonymous_variant 0.71 pyrazinamide
sigE 1364697 c.285G>C synonymous_variant 0.74 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.76 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.76 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 0.76 pyrazinamide
sigE 1364718 c.306C>G synonymous_variant 0.76 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.76 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.79 pyrazinamide
sigE 1364727 c.315C>T synonymous_variant 0.8 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 0.84 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.81 pyrazinamide
sigE 1364767 c.355_357delAGGinsCC frameshift_variant&missense_variant 0.82 pyrazinamide Uncertain significance
sigE 1364782 c.370_372delGTCinsCG frameshift_variant&missense_variant 0.8 pyrazinamide Uncertain significance
sigE 1364790 c.378T>C synonymous_variant 0.81 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.8 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.79 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.79 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.8 pyrazinamide
sigE 1364820 c.408A>T synonymous_variant 0.82 pyrazinamide
sigE 1364839 c.427_429delTTGinsCA frameshift_variant&missense_variant 0.82 pyrazinamide Uncertain significance
sigE 1364847 c.435G>C synonymous_variant 0.77 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.77 pyrazinamide
sigE 1364860 c.448_450delCGCinsAG frameshift_variant&missense_variant 0.77 pyrazinamide Uncertain significance
sigE 1364865 c.453G>C synonymous_variant 0.77 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.77 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.84 pyrazinamide Uncertain significance
sigE 1364910 c.498G>T synonymous_variant 0.91 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.9 pyrazinamide
sigE 1364918 p.Asp169Ala missense_variant 0.9 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.88 pyrazinamide
sigE 1364931 c.519C>G synonymous_variant 0.88 pyrazinamide
sigE 1364950 c.538_540delGCAinsTG frameshift_variant&stop_gained 0.83 pyrazinamide Uncertain significance
sigE 1364961 c.549A>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.63 pyrazinamide
sigE 1364980 c.568_570delTTGinsCC frameshift_variant&missense_variant 0.63 pyrazinamide Uncertain significance
sigE 1364984 p.Ala191Asp missense_variant 0.63 pyrazinamide
sigE 1364988 c.576G>C synonymous_variant 0.63 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.6 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.6 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.58 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.58 pyrazinamide
sigE 1365036 c.624T>A synonymous_variant 0.44 pyrazinamide
atpE 1461050 c.6C>T synonymous_variant 0.43 bedaquiline
atpE 1461071 c.27C>G synonymous_variant 0.55 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.7 bedaquiline
atpE 1461107 c.63C>A synonymous_variant 0.67 bedaquiline
atpE 1461113 c.69C>T synonymous_variant 0.72 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 0.81 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.81 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.81 bedaquiline
atpE 1461147 c.103_105delCTTinsTG frameshift_variant&missense_variant 0.85 bedaquiline
atpE 1461153 p.Ser37Ala missense_variant 0.88 bedaquiline Uncertain significance
atpE 1461158 c.114T>C synonymous_variant 0.88 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.88 bedaquiline Uncertain significance
atpE 1461164 c.120C>T synonymous_variant 0.88 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.88 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.88 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.85 bedaquiline
atpE 1461188 c.144G>A synonymous_variant 0.85 bedaquiline
atpE 1461197 c.153A>T synonymous_variant 0.78 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 0.73 bedaquiline
atpE 1461215 c.171C>G synonymous_variant 0.71 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.71 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.71 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.71 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.59 bedaquiline
rrs 1471845 n.-1G>T upstream_gene_variant 0.45 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472024 n.179G>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472025 n.180A>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183delAinsTG non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472038 n.194dupG non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472048 n.203T>G non_coding_transcript_exon_variant 0.84 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472844 n.1000dupG non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1005delT non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472856 n.1012delA non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1018dupT non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472953 n.1108_1109insA non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112_1113delCAinsT non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472975 n.1130T>A non_coding_transcript_exon_variant 0.29 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473654 n.-4G>T upstream_gene_variant 0.44 capreomycin
linezolid
rrl 1473658 n.1T>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1474287 n.630_649delTCCTTTTCCTCTCCGGAGGAinsCTCGATTTATC non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474418 n.761C>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474420 n.764_769delGCGCAT non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474428 n.771C>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474430 n.773C>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474710 n.1053delTinsGCAA non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474955 n.1298T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474956 n.1299C>G non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474957 n.1300C>A non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474958 n.1301A>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1474969 n.1312G>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474970 n.1313G>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474971 n.1314T>G non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474972 n.1315G>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474995 n.1338T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474997 n.1340A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1475008 n.1351C>G non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475009 n.1352G>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475015 n.1358_1360delCCGinsTTCA non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475403 n.1746T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475619 n.1964dupT non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.93 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476025 n.2368G>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.33 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.32 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.3 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036delGinsCA non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
inhA 1673646 c.-556T>C upstream_gene_variant 0.83 ethionamide
isoniazid
inhA 1673652 c.-550C>A upstream_gene_variant 0.75 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.77 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.77 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673673 c.-529C>T upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.83 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673697 c.-505G>C upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1673706 c.-496C>A upstream_gene_variant 0.79 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.79 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.79 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.8 ethionamide
isoniazid
fabG1 1673748 p.Glu103Asp missense_variant 0.74 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.74 ethionamide
isoniazid
inhA 1673757 c.-445G>A upstream_gene_variant 0.74 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.74 ethionamide
isoniazid
inhA 1673778 c.-424C>G upstream_gene_variant 0.75 ethionamide
isoniazid
inhA 1673799 c.-403T>C upstream_gene_variant 0.68 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.63 ethionamide
isoniazid
inhA 1673808 c.-394A>C upstream_gene_variant 0.61 ethionamide
isoniazid
fabG1 1673816 p.Ser126Thr missense_variant 0.61 ethionamide
isoniazid
inhA 1673877 c.-325C>G upstream_gene_variant 0.68 ethionamide
isoniazid
inhA 1673901 c.-301A>T upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673904 c.-298C>G upstream_gene_variant 0.77 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.77 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.71 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1673941 c.502_504delGCCinsTG frameshift_variant&missense_variant 0.68 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.68 ethionamide
isoniazid
fabG1 1673960 p.Ala174Val missense_variant 0.74 ethionamide
isoniazid
inhA 1673973 c.-229G>C upstream_gene_variant 0.74 ethionamide
isoniazid Uncertain significance
inhA 1673976 c.-226T>C upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673979 c.-223G>C upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673982 c.-220G>C upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673988 c.-214G>T upstream_gene_variant 0.74 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.86 ethionamide
isoniazid
inhA 1674015 c.-187C>T upstream_gene_variant 0.83 ethionamide
isoniazid Uncertain significance
inhA 1674021 c.-181G>C upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.74 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.63 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 0.63 ethionamide
isoniazid
inhA 1674048 c.-154G>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGT frameshift_variant&missense_variant 0.71 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1674060 c.-142A>C upstream_gene_variant 0.74 ethionamide
isoniazid
inhA 1674069 c.-133G>C upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1674072 c.-130C>G upstream_gene_variant 0.7 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.67 ethionamide
isoniazid
fabG1 1674083 p.Ala215Glu missense_variant 0.7 ethionamide
isoniazid
inhA 1674093 c.-109C>G upstream_gene_variant 0.67 ethionamide
isoniazid
inhA 1674096 c.-106G>C upstream_gene_variant 0.67 ethionamide
isoniazid
fabG1 1674098 p.Val220Ala missense_variant 0.7 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 0.7 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.61 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 0.44 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 0.44 ethionamide
isoniazid
inhA 1674463 p.Leu88Ile missense_variant 0.64 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.69 ethionamide
isoniazid
inhA 1674474 c.273G>C synonymous_variant 0.74 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674502 p.Thr101Ser missense_variant 0.7 ethionamide
isoniazid
inhA 1674516 c.315C>A synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 0.82 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674540 c.339C>T synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.82 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674552 c.351C>G synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.8 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.8 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.76 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 0.69 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674628 c.427_428delTCinsAG synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674639 c.438C>T synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.7 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674687 c.486G>C synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 0.71 ethionamide
isoniazid
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 0.58 pyrazinamide
rpsA 1833547 c.6G>A synonymous_variant 0.65 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.7 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.77 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.8 pyrazinamide
rpsA 1833598 c.57C>T synonymous_variant 0.8 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.81 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.8 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.8 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.81 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.89 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.9 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.87 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.87 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.9 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.9 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.89 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.83 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.83 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.84 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.84 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 0.84 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.84 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.84 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.88 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.92 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.92 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.92 pyrazinamide
rpsA 1833901 c.360G>A synonymous_variant 0.91 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.91 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.94 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.92 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834135 c.594G>T synonymous_variant 0.78 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.7 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.63 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.61 pyrazinamide
rpsA 1834169 c.628_630delACCinsGG frameshift_variant&missense_variant 0.57 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834190 c.649_650delTCinsAG synonymous_variant 0.61 pyrazinamide
rpsA 1834193 c.652_654delTCGinsAGC synonymous_variant 0.57 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.7 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834282 c.741C>T synonymous_variant 0.84 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.9 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834402 c.861C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.91 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.87 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.87 pyrazinamide
rpsA 1834513 c.972C>A synonymous_variant 0.86 pyrazinamide
rpsA 1834519 c.978G>T synonymous_variant 0.83 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.83 pyrazinamide
rpsA 1834528 c.987T>G synonymous_variant 0.83 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.84 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.83 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.85 pyrazinamide
rpsA 1834556 p.Ala339Gln missense_variant 0.85 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.89 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.89 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 0.78 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.78 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.75 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.75 pyrazinamide
rpsA 1834741 c.1200C>T synonymous_variant 0.75 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.76 pyrazinamide
rpsA 1834761 p.Phe407Tyr missense_variant 0.76 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.76 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.72 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.71 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.71 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.71 pyrazinamide
rpsA 1834787 c.1246_1248delGCTinsTC frameshift_variant&missense_variant 0.71 pyrazinamide Uncertain significance
rpsA 1834792 c.1251G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 0.81 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 0.81 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.78 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.78 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 0.76 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.81 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 0.81 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.79 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.81 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.78 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.8 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.7 linezolid
tsnR 1853444 c.-162C>G upstream_gene_variant 0.67 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.6 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.57 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.55 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
bacA 2064996 c.-268G>T upstream_gene_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
katG 2156025 c.87C>A synonymous_variant 1.0 isoniazid Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
kasA 2517917 c.-198G>T upstream_gene_variant 0.88 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.87 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.84 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.78 isoniazid
kasA 2517993 c.-122G>A upstream_gene_variant 0.77 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.64 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.5 isoniazid
kasA 2518028 c.-87G>A upstream_gene_variant 0.41 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.63 isoniazid
kasA 2518150 c.36C>G synonymous_variant 0.67 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.63 isoniazid
kasA 2518156 c.42T>C synonymous_variant 0.63 isoniazid
kasA 2518159 c.45G>C synonymous_variant 0.63 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.65 isoniazid
kasA 2518180 c.66G>C synonymous_variant 0.68 isoniazid
kasA 2518187 p.Ile25Val missense_variant 0.68 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.68 isoniazid
kasA 2518193 p.Pro27Ala missense_variant 0.68 isoniazid
kasA 2518219 c.105T>C synonymous_variant 0.78 isoniazid
kasA 2518223 c.109T>C synonymous_variant 0.74 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.72 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.73 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.73 isoniazid
kasA 2518255 c.141A>G synonymous_variant 0.73 isoniazid
kasA 2518258 c.144C>T synonymous_variant 0.73 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.59 isoniazid
kasA 2518488 p.Ser125Thr missense_variant 0.61 isoniazid
kasA 2518496 p.Leu128Ala missense_variant 0.59 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.62 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.62 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.65 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.67 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.69 isoniazid
kasA 2518540 c.426T>G synonymous_variant 0.72 isoniazid
kasA 2518555 c.441C>G synonymous_variant 0.76 isoniazid
kasA 2518564 c.450C>G synonymous_variant 0.75 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.74 isoniazid
kasA 2518588 c.474T>G synonymous_variant 0.72 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.72 isoniazid
kasA 2518595 c.481_483delCGCinsAG frameshift_variant&missense_variant 0.71 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.67 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.7 isoniazid
kasA 2518618 c.504G>C synonymous_variant 0.72 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.73 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.67 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.62 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 0.65 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.61 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.69 isoniazid
ahpC 2726582 c.390G>C synonymous_variant 0.44 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.56 isoniazid
ahpC 2726597 c.405C>G synonymous_variant 0.53 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.53 isoniazid
ahpC 2726612 c.420C>G synonymous_variant 0.64 isoniazid
ahpC 2726633 c.441C>G synonymous_variant 0.62 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.62 isoniazid
ahpC 2726648 c.456T>C synonymous_variant 0.62 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 0.57 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.54 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.54 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.52 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.52 isoniazid
ahpC 2726702 c.510C>G synonymous_variant 0.54 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.38 isoniazid
Rv2477c 2782453 c.1590C>T synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782462 c.1581C>T synonymous_variant 0.45 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 p.Asp516Glu missense_variant 0.57 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782501 c.1542T>C synonymous_variant 0.52 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782516 c.1527C>T synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782525 c.1518C>T synonymous_variant 0.52 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782546 c.1495_1497delCGCinsAG frameshift_variant&missense_variant 0.5 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782549 c.1494T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782564 c.1479G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782573 c.1470C>T synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.7 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>T synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>T synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783005 c.1038C>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.78 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>T synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783083 c.960G>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783155 c.888C>G synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783185 c.858G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783218 c.825C>G synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.43 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783233 c.808_810delTTGinsCC frameshift_variant&missense_variant 0.4 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783239 p.Glu268Asp missense_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783284 c.759G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Val missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.57 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783413 c.630G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783431 p.Ser204Glu missense_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783497 c.544_546delTTGinsCC frameshift_variant&missense_variant 0.79 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783502 c.541T>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783575 c.468G>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783877 p.Lys56Gln missense_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783901 c.142T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2680 2996344 c.240C>A synonymous_variant 0.33 capreomycin Not assoc w R - Interim
Rv2681 2996353 c.-386G>C upstream_gene_variant 0.4 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.38 capreomycin
Rv2680 2996366 c.262_264delTATinsCC frameshift_variant&missense_variant 0.36 capreomycin Uncertain significance
Rv2681 2996374 c.-365G>C upstream_gene_variant 0.36 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 0.36 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 0.35 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 0.35 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>G upstream_gene_variant 0.35 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.36 capreomycin
Rv2680 2996404 p.Ile100Met missense_variant 0.36 capreomycin
Rv2681 2996407 c.-332C>G upstream_gene_variant 0.38 capreomycin
Rv2681 2996410 c.-329G>C upstream_gene_variant 0.38 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.36 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.38 capreomycin
Rv2681 2996440 c.-299G>C upstream_gene_variant 0.48 capreomycin
Rv2681 2996443 c.-296T>C upstream_gene_variant 0.5 capreomycin
Rv2680 2996446 c.342A>G synonymous_variant 0.55 capreomycin Not assoc w R - Interim
Rv2681 2996458 c.-281C>G upstream_gene_variant 0.57 capreomycin
Rv2681 2996473 c.-266G>C upstream_gene_variant 0.47 capreomycin
Rv2681 2996476 c.-263A>G upstream_gene_variant 0.5 capreomycin
Rv2681 2996482 c.-257T>C upstream_gene_variant 0.47 capreomycin
Rv2680 2996488 c.384G>C synonymous_variant 0.43 capreomycin Not assoc w R - Interim
Rv2681 2997325 p.Ala196Val missense_variant 1.0 capreomycin Uncertain significance
thyA 3073839 c.633T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.52 para-aminosalicylic_acid
thyA 3073888 p.Ser195Glu missense_variant 0.53 para-aminosalicylic_acid
thyA 3073890 c.580_582delTTGinsCC frameshift_variant&missense_variant 0.56 para-aminosalicylic_acid
thyA 3073893 c.579C>A synonymous_variant 0.56 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3073950 c.522G>T synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.6 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.54 para-aminosalicylic_acid
mtrB 3625069 c.1543_1545delCTTinsTG frameshift_variant&synonymous_variant 0.58 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625078 c.-168G>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Lys missense_variant 0.58 bedaquiline
rifampicin
lpqB 3625117 c.-207T>C upstream_gene_variant 0.63 bedaquiline
rifampicin
lpqB 3625122 c.-212C>A upstream_gene_variant 0.59 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.59 bedaquiline
rifampicin
lpqB 3625126 c.-216G>A upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625135 c.-225A>T upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625144 c.-234G>A upstream_gene_variant 0.56 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.6 bedaquiline
rifampicin
lpqB 3625156 c.-246G>A upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 0.62 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625168 c.-258G>T upstream_gene_variant 0.68 bedaquiline
rifampicin
lpqB 3625183 c.-273G>T upstream_gene_variant 0.63 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625198 c.-288C>T upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.64 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.72 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625246 c.-336G>A upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625283 p.Val444Ala missense_variant 0.83 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625291 p.Glu441Asp missense_variant 0.89 bedaquiline
rifampicin
lpqB 3625312 c.-402G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 0.67 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625336 c.-426C>T upstream_gene_variant 0.64 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625357 c.-447T>C upstream_gene_variant 0.46 bedaquiline
rifampicin
lpqB 3625663 c.-753G>C upstream_gene_variant 0.65 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
lpqB 3625672 c.-762G>A upstream_gene_variant 0.71 bedaquiline
rifampicin
lpqB 3625683 c.-773C>T upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3625687 c.927G>A synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625690 c.-780T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3625708 c.906C>T synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
lpqB 3625723 c.-813C>G upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.83 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625766 p.Ser283His missense_variant 0.83 bedaquiline
rifampicin
lpqB 3625795 c.-885G>C upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625798 c.-888G>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3625804 c.808_810delAGGinsCC frameshift_variant&missense_variant 0.79 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625840 c.-930A>G upstream_gene_variant 0.66 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 0.65 bedaquiline
rifampicin
lpqB 3625846 c.-936G>C upstream_gene_variant 0.67 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625876 c.-966G>A upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3625897 c.715_717delGTGinsCT frameshift_variant&missense_variant 0.67 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625903 c.709_711delGTGinsAC frameshift_variant&missense_variant 0.62 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625909 c.-999T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3625914 p.Ser234Ala missense_variant 0.71 bedaquiline
rifampicin
mtrB 3625924 c.690G>C synonymous_variant 0.57 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.57 bedaquiline
rifampicin
mtrB 3625930 p.Gly228Ala missense_variant 0.53 bedaquiline
rifampicin
mtrB 3625943 p.Val224Gly missense_variant 0.47 bedaquiline
rifampicin
mtrB 3625945 c.669A>C synonymous_variant 0.47 bedaquiline
rifampicin
mtrB 3625951 c.663A>C synonymous_variant 0.4 bedaquiline
rifampicin
mtrB 3625956 p.Leu220Val missense_variant 0.4 bedaquiline
rifampicin
mtrB 3625966 c.648C>G synonymous_variant 0.37 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3626702 c.-89G>C upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 0.65 bedaquiline
rifampicin
mtrB 3626714 c.-101G>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrA 3626741 c.609C>G synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 0.75 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626795 c.-182C>T upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>A upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3626900 c.-287G>A upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.42 bedaquiline
rifampicin
mtrA 3626906 c.442_444delAACinsCG frameshift_variant&missense_variant 0.47 bedaquiline
rifampicin
mtrA 3626909 c.441C>G synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626912 c.438T>C synonymous_variant 0.53 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626927 c.-314G>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 0.71 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrA 3626949 p.Ala134Gly missense_variant 0.7 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.74 bedaquiline
rifampicin Uncertain significance
mtrB 3626987 c.-374C>G upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3626992 c.-379C>T upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3626995 c.-382C>A upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrA 3626999 c.351G>A synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627002 c.-389G>T upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627005 c.-392G>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627014 c.-401G>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627017 c.-404G>A upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.8 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3627086 c.-473C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627092 c.-479C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627113 c.-500C>T upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627131 c.-518C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627134 c.-521C>T upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrA 3627137 c.211_213delTTGinsCC frameshift_variant&missense_variant 0.78 bedaquiline
rifampicin
mtrB 3627149 c.-536G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.67 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627215 c.-602G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3627230 c.-617G>A upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627233 c.-620T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627263 c.-650C>T upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCC frameshift_variant&missense_variant 0.67 bedaquiline
rifampicin
mtrA 3627305 c.43_45delGCTinsCG frameshift_variant&synonymous_variant 0.7 bedaquiline
rifampicin
mtrA 3627311 c.39C>T synonymous_variant 0.7 bedaquiline Not assoc w R - Interim
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627320 c.-707C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627325 c.-712T>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.65 bedaquiline
rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.71 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 0.71 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 0.71 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877565 c.942delC frameshift_variant 0.71 rifampicin
rpoA 3877568 p.Ser314Arg missense_variant 0.71 rifampicin
rpoA 3877569 c.939G>T synonymous_variant 0.77 rifampicin
rpoA 3877572 c.935dupC frameshift_variant 0.79 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.96 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 0.96 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.96 rifampicin
rpoA 3877677 c.831G>T synonymous_variant 0.96 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.95 rifampicin
rpoA 3877707 c.801G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.94 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 0.93 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877821 c.687C>G synonymous_variant 0.94 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.97 rifampicin
rpoA 3877860 c.648C>T synonymous_variant 0.97 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.98 rifampicin
rpoA 3877881 c.627G>C synonymous_variant 0.96 rifampicin
rpoA 3877884 c.624G>C synonymous_variant 0.98 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 0.98 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.98 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.92 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.9 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.82 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3878010 c.498C>G synonymous_variant 0.63 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.87 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 0.81 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.83 rifampicin
rpoA 3878142 p.Gly122Glu missense_variant 0.88 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.89 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>T synonymous_variant 0.9 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 0.92 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878244 c.264G>A synonymous_variant 0.9 rifampicin
rpoA 3878250 c.258C>G synonymous_variant 0.9 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 0.9 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.9 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.9 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.89 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>T synonymous_variant 0.93 rifampicin
rpoA 3878316 c.192C>T synonymous_variant 0.9 rifampicin
rpoA 3878322 c.186A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>G synonymous_variant 0.85 rifampicin
rpoA 3878337 c.171T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.83 rifampicin
rpoA 3878358 c.150C>G synonymous_variant 0.85 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.86 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.86 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.85 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.87 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.84 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878394 c.114G>T synonymous_variant 0.84 rifampicin
rpoA 3878406 c.102G>T synonymous_variant 0.8 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.72 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.57 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.65 rifampicin
rpoA 3879117 c.-610C>T upstream_gene_variant 0.56 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.43 rifampicin
rpoA 3879124 c.-618_-617delTGinsGC upstream_gene_variant 0.4 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.38 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.43 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.46 rifampicin
ddn 3986648 c.-196C>G upstream_gene_variant 0.69 delamanid
pretomanid
ddn 3986657 c.-187C>G upstream_gene_variant 0.67 delamanid
pretomanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.67 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.59 delamanid
pretomanid
ddn 3986673 c.-171C>T upstream_gene_variant 0.63 delamanid
pretomanid
ddn 3986681 c.-163C>G upstream_gene_variant 0.66 delamanid
pretomanid
ddn 3986696 c.-148G>T upstream_gene_variant 0.5 delamanid
pretomanid
ddn 3986699 c.-145C>G upstream_gene_variant 0.5 delamanid
pretomanid
ddn 3986714 c.-130C>G upstream_gene_variant 0.44 delamanid
pretomanid
clpC1 4038302 c.2403C>G synonymous_variant 0.55 pyrazinamide
clpC1 4038308 c.2395_2397delGTGinsCC frameshift_variant&missense_variant 0.5 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.48 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.48 pyrazinamide
clpC1 4038325 p.Val794Ile missense_variant 0.48 pyrazinamide
clpC1 4038335 c.2370C>G synonymous_variant 0.46 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.52 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.5 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.5 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.52 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.55 pyrazinamide
clpC1 4038392 c.2313C>G synonymous_variant 0.55 pyrazinamide
clpC1 4038395 c.2310C>G synonymous_variant 0.55 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCC frameshift_variant&missense_variant 0.48 pyrazinamide
clpC1 4038407 c.2298G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038416 c.2289C>A synonymous_variant 0.64 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.65 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.62 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.54 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.54 pyrazinamide
clpC1 4038449 c.2256C>G synonymous_variant 0.54 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.54 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.56 pyrazinamide
clpC1 4038463 p.Ala748Thr missense_variant 0.56 pyrazinamide
clpC1 4038474 p.Ser744Ala missense_variant 0.56 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.54 pyrazinamide
clpC1 4038490 p.Ala739Ser missense_variant 0.54 pyrazinamide
clpC1 4038491 c.2214C>G synonymous_variant 0.54 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.54 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.52 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 0.56 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.56 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.77 pyrazinamide
clpC1 4038587 c.2116_2118delCGCinsAG frameshift_variant&missense_variant 0.91 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.91 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.91 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.94 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.95 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.94 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.94 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>T synonymous_variant 0.97 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038842 c.1863G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>C synonymous_variant 0.92 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.92 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.93 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.94 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.93 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.92 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4038986 c.1719C>T synonymous_variant 0.92 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039009 c.1696C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039082 c.1623C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.87 pyrazinamide
clpC1 4039193 c.1512C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.86 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039259 c.1446G>A synonymous_variant 0.8 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 0.68 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.77 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.76 pyrazinamide
clpC1 4039316 c.1389G>A synonymous_variant 0.77 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.77 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 0.8 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.85 pyrazinamide
clpC1 4039347 p.Arg453Lys missense_variant 0.85 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.91 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.91 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039466 c.1239T>G synonymous_variant 0.89 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039559 c.1146C>T synonymous_variant 0.87 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039576 p.Ala377Ser missense_variant 0.87 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039628 c.1077C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.87 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.89 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.88 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.89 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4039922 c.783C>T synonymous_variant 0.86 pyrazinamide
clpC1 4039925 c.780C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039985 c.720G>A synonymous_variant 0.86 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.86 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.86 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.85 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.83 pyrazinamide
clpC1 4040121 p.Lys195Arg missense_variant 0.8 pyrazinamide
clpC1 4040123 c.582G>A synonymous_variant 0.8 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.71 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.68 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>C synonymous_variant 0.66 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.69 pyrazinamide
clpC1 4040198 c.505_507delTTGinsCC frameshift_variant&missense_variant 0.61 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.61 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.61 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.61 pyrazinamide
clpC1 4040214 p.Ser164Asn missense_variant 0.61 pyrazinamide
clpC1 4040219 c.484_486delTCCinsGG frameshift_variant&missense_variant 0.61 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.62 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.62 pyrazinamide
clpC1 4040240 c.465C>G synonymous_variant 0.72 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.81 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 0.84 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.85 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040270 c.435C>T synonymous_variant 0.88 pyrazinamide
clpC1 4040273 c.432T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.429C>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040279 c.426C>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040312 c.393G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.93 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.92 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.92 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040393 c.312G>T synonymous_variant 0.94 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040414 c.291G>A synonymous_variant 0.88 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.87 pyrazinamide
clpC1 4040429 c.274_276delTTGinsCC frameshift_variant&missense_variant 0.87 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 0.87 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.89 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.89 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.9 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040537 c.168G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.89 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.88 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.88 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.83 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.83 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.83 pyrazinamide
clpC1 4040597 c.108C>A synonymous_variant 0.83 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.83 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.84 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.86 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.77 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.75 pyrazinamide
clpC1 4040690 c.15T>C synonymous_variant 0.62 pyrazinamide
glpK 4138451 c.1305T>C synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138464 p.Gly431Ala missense_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138487 c.1267_1269delTTGinsCC frameshift_variant&missense_variant 0.63 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138490 c.1266G>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138495 p.Gln421Glu missense_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138498 p.Leu420Met missense_variant 0.63 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138500 p.Arg419His missense_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138505 c.1251T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138514 c.1242A>C synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 c.1239A>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138532 c.1224G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138562 c.1194G>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138589 c.1167C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139285 c.471A>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139302 p.Leu152Val missense_variant 0.85 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139312 c.444T>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139318 c.438T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139321 c.435T>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139324 c.432A>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139327 c.429G>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139351 c.405C>T synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139354 c.400_402delCTGinsGC frameshift_variant&missense_variant 0.79 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139359 p.Asn133Asp missense_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139360 c.396A>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139363 c.393T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139366 c.390T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139372 c.384A>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139375 c.381T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139387 c.369G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139408 c.348T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139417 c.339A>G synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139420 c.336T>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139432 c.324C>T synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139637 p.Ala40Gly missense_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139639 c.115_117delGTGinsAC frameshift_variant&missense_variant 0.6 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139648 c.108T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139652 p.His35Gly missense_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4240717 c.855T>C synonymous_variant 0.48 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embC 4240729 c.867C>G synonymous_variant 0.53 ethambutol
embC 4240736 p.Ser292Ala missense_variant 0.61 ethambutol
embC 4240759 c.897C>G synonymous_variant 0.67 ethambutol
embC 4240765 c.903C>G synonymous_variant 0.7 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.7 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.66 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.66 ethambutol
embC 4240795 c.933C>G synonymous_variant 0.66 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.62 ethambutol
embC 4240822 c.960C>T synonymous_variant 0.62 ethambutol Not assoc w R - Interim
embC 4240825 c.963G>A synonymous_variant 0.62 ethambutol
embC 4240826 p.Ala322Ser missense_variant 0.62 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.65 ethambutol
embC 4240843 c.981C>T synonymous_variant 0.61 ethambutol
embA 4244220 c.988C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247395 c.882C>G synonymous_variant 0.47 ethambutol
embB 4247398 c.885G>C synonymous_variant 0.44 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.47 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.38 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.39 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.38 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.39 ethambutol
embB 4247996 p.Ala495Phe missense_variant 0.52 ethambutol
embB 4248008 c.1495_1497delCTGinsAC frameshift_variant&missense_variant 0.59 ethambutol
embB 4248011 p.Ser500Ala missense_variant 0.57 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.67 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.57 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.55 ethambutol
embB 4248052 c.1539G>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embB 4248055 c.1542G>C synonymous_variant 0.6 ethambutol
embB 4248057 p.Ser515Asn missense_variant 0.6 ethambutol
embB 4248063 p.Ala517Glu missense_variant 0.6 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.6 ethambutol
embB 4248085 c.1572T>G synonymous_variant 0.55 ethambutol Not assoc w R - Interim
embB 4248097 c.1584C>G synonymous_variant 0.41 ethambutol
embB 4248295 c.1782C>T synonymous_variant 0.4 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.39 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.35 ethambutol
embB 4248325 c.1812G>C synonymous_variant 0.35 ethambutol
embB 4248328 c.1815G>A synonymous_variant 0.33 ethambutol
embB 4248334 c.1821C>G synonymous_variant 0.33 ethambutol
embB 4248341 p.Thr610Ala missense_variant 0.32 ethambutol
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R