TB-Profiler result

Run: ERR3445501
Summary

Run ID: ERR3445501

Sample name:

Date: 2024-04-16T12:20:39.981504

Number of reads: 847560

Percentage reads mapped: 20.48

Median coverage: 13.0

Strain: La1.7.1;La1.7.X-unk4;lineage7

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.7.1 M.bovis None 0.11
lineage7 Lineage 7 None 0.18
La1.7.X-unk4 M.bovis None 1.0
lineage6.2.1 West-Africa 2 RD702 0.11
La1 M.bovis None 0.34
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.421_423delTTGinsCC Assoc w R High-level resistance
ethambutol embB p.Asp311Gly Mutation from literature
pyrazinamide pncA p.His57Asp Assoc w R
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.641_644delTCGG Assoc w R - Interim
c.636_637insGCCG Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.421_423delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.1189_1191delAAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2314_2316delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2338_2340delCGCinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.641_644delTCGG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.636_637insGCCG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.85 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491203 c.421_423delCAGinsGA frameshift_variant&missense_variant 0.67 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.71 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304119 c.1189_1191delAAAinsCG frameshift_variant&missense_variant 0.63 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305244 c.2314_2316delTTGinsCC frameshift_variant&missense_variant 0.42 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305268 c.2338_2340delCGCinsAG frameshift_variant&missense_variant 0.46 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.48 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155689 c.421_423delTTGinsCC frameshift_variant&missense_variant 0.5 isoniazid Assoc w R High-level resistance
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide Assoc w R
pepQ 2859774 c.641_644delTCGG frameshift_variant 0.37 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
pepQ 2859782 c.636_637insGCCG frameshift_variant 0.35 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
embB 4247445 p.Asp311Gly missense_variant 0.46 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 627 c.627G>A synonymous_variant 0.58 isoniazid
dnaA 633 c.633T>G synonymous_variant 0.58 isoniazid
dnaA 636 c.636C>G synonymous_variant 0.61 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 648 c.648C>T synonymous_variant 0.64 isoniazid
dnaA 654 c.654A>G synonymous_variant 0.66 isoniazid
dnaA 663 c.663A>C synonymous_variant 0.66 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>C synonymous_variant 0.68 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.7 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.7 isoniazid
dnaA 699 c.699G>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 702 c.702C>G synonymous_variant 0.7 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.68 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.72 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 0.71 isoniazid
dnaA 750 c.750C>G synonymous_variant 0.69 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.71 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.67 isoniazid
dnaA 769 c.769_771delGCAinsTC frameshift_variant&missense_variant 0.65 isoniazid Uncertain significance
dnaA 792 c.792C>T synonymous_variant 0.66 isoniazid
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.66 isoniazid Uncertain significance
dnaA 798 c.798C>T synonymous_variant 0.66 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 0.68 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.68 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 0.69 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.71 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.7 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.71 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.71 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 0.71 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.71 isoniazid
dnaA 876 c.876C>A synonymous_variant 0.68 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.72 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.71 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.67 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.63 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.63 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.5 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.58 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.57 isoniazid
dnaA 1237 c.1237_1239delGCGinsAC frameshift_variant&missense_variant 0.52 isoniazid Uncertain significance
dnaA 1242 c.1242G>A synonymous_variant 0.55 isoniazid
dnaA 1243 p.Thr415Ala missense_variant 0.55 isoniazid Uncertain significance
dnaA 1254 c.1254T>G synonymous_variant 0.6 isoniazid
dnaA 1275 p.Asp425Glu missense_variant 0.64 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.64 isoniazid
dnaA 1282 p.Val428Ile missense_variant 0.61 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.62 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.62 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.62 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.62 isoniazid
dnaA 1314 c.1314A>C synonymous_variant 0.64 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.64 isoniazid
dnaA 1320 c.1320G>C synonymous_variant 0.67 isoniazid
dnaA 1323 c.1323C>A synonymous_variant 0.64 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 0.67 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 0.61 isoniazid
gyrB 6139 c.900G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6193 c.954G>A synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6199 c.960C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6204 p.Ser322Thr missense_variant 0.63 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.68 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6304 c.-998C>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6322 c.-980G>A upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6326 c.-976_-975delAGinsTC upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 0.85 levofloxacin Uncertain significance
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrB 6398 p.Val387Ile missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrB 6410 p.Gln391Glu missense_variant 0.56 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6430 p.Glu397Asp missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6440 p.Thr401Ala missense_variant 0.64 levofloxacin
moxifloxacin
gyrB 6445 p.Asp402Glu missense_variant 0.64 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6556 c.-746C>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrB 6559 c.1320C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6592 c.-710C>A upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6604 c.-698G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6724 c.-578G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6745 c.-557T>A upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 6763 c.-539G>A upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6766 c.-536G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.72 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.61 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6976 c.-326A>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7015 c.-287G>A upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>A upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Arg missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>G upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 7047 p.Lys603Thr missense_variant 0.79 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.79 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7096 c.-206G>A upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7111 c.-191C>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7210 p.Asp657Glu missense_variant 0.73 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7415 c.114C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7424 c.123G>A synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7427 c.126G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7475 c.174A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7484 c.183T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7490 c.189C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7614 c.313C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7685 c.384G>A synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7688 c.387C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7700 c.399G>A synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7703 c.402G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7709 c.408G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7781 c.480G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7802 c.501C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7817 c.516C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7823 c.522G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7832 c.531G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8108 c.807G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 c.898_900delTCCinsGG frameshift_variant&missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8231 c.930C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCT frameshift_variant&missense_variant 0.48 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8330 c.1029C>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8360 c.1059G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.48 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8400 p.Asp367Asn missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8495 c.1194C>T synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251_1254delCCGGinsGC frameshift_variant&synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8559 c.1258_1260delGGAinsAGGGC frameshift_variant&missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 8571 c.1270C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8588 p.Glu429Asp missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8786 c.1485T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8817 p.Ser506Ala missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8885 c.1584C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.87 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9002 c.1701C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.74 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9134 c.1833C>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9217 p.Asp639Ala missense_variant 0.71 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 491007 c.225G>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491037 c.255C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491073 c.291C>T synonymous_variant 0.81 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491077 p.Asn99Asp missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>T synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491176 c.394C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491190 c.408G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Lys missense_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Leu missense_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491249 p.Arg156His missense_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491251 p.Leu157Thr missense_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491265 c.483G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 491491 p.Pro237Thr missense_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491505 c.723G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491536 c.754C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
mshA 575686 c.339G>A synonymous_variant 0.5 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.5 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.5 ethionamide
isoniazid Not assoc w R - Interim
mshA 575701 c.354G>A synonymous_variant 0.54 ethionamide
isoniazid
mshA 575704 c.357T>G synonymous_variant 0.54 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 0.54 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575722 c.375G>C synonymous_variant 0.7 ethionamide
isoniazid
mshA 575725 c.378C>G synonymous_variant 0.63 ethionamide
isoniazid
mshA 575728 c.381C>G synonymous_variant 0.64 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.67 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.77 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 0.78 ethionamide
isoniazid
mshA 575752 c.405G>A synonymous_variant 0.78 ethionamide
isoniazid Not assoc w R - Interim
mshA 575764 c.417C>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.81 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.8 ethionamide
isoniazid Not assoc w R - Interim
mshA 575806 c.459G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575816 c.469C>T synonymous_variant 0.78 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.78 ethionamide
isoniazid
mshA 575830 c.483C>T synonymous_variant 0.78 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575851 c.504C>G synonymous_variant 0.77 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.72 ethionamide
isoniazid
mshA 575869 c.522G>A synonymous_variant 0.71 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.77 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.78 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.64 ethionamide
isoniazid
ccsA 620197 p.Gln103Ala missense_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620236 c.346C>T synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620296 p.Pro136Ala missense_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620299 c.409C>T synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620311 p.Leu141Val missense_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620316 c.426G>C synonymous_variant 0.36 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620319 c.429C>G synonymous_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.39 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.37 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>C synonymous_variant 0.37 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620355 p.Leu156Phe missense_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>A synonymous_variant 0.45 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620406 c.516G>A synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.44 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.58 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.53 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.53 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 0.53 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 0.53 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 0.53 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 0.59 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.68 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620676 c.786C>T synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620679 c.789C>G synonymous_variant 0.81 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 0.82 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620688 c.798G>C synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>T synonymous_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620754 c.864G>C synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620758 p.Arg290Lys missense_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 0.59 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 620802 c.912C>G synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.5 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
Rv0565c 657635 c.-167_-165delAGCinsTCG upstream_gene_variant 0.73 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.73 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.73 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.79 ethionamide
Rv0565c 657668 c.-200_-198delACCinsGG upstream_gene_variant 0.69 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.69 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.69 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 0.65 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.61 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.65 ethionamide
Rv0565c 657722 c.-254_-252delAACinsCG upstream_gene_variant 0.65 ethionamide
nusG 734418 c.165C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
nusG 734421 c.168A>C synonymous_variant 0.77 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.76 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.81 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.83 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.88 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.86 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.91 rifampicin
nusG 734508 c.255C>G synonymous_variant 0.9 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.81 rifampicin
nusG 734566 c.313C>T synonymous_variant 0.76 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.79 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.5 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.64 rifampicin
nusG 734850 c.597C>A synonymous_variant 0.64 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.64 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.64 rifampicin
nusG 734859 c.606G>C synonymous_variant 0.64 rifampicin
nusG 734862 c.609C>G synonymous_variant 0.64 rifampicin
nusG 734863 p.Thr204Ser missense_variant 0.64 rifampicin
nusG 734871 c.618C>T synonymous_variant 0.64 rifampicin
nusG 734889 c.636G>A synonymous_variant 0.69 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.69 rifampicin
rpoB 760060 p.Tyr85Ser missense_variant 0.45 rifampicin
rpoB 760068 c.262_264delTCTinsAGC synonymous_variant 0.53 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760094 c.288G>C synonymous_variant 0.72 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.68 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.68 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.68 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.66 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 0.67 rifampicin
rpoB 760139 c.333A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.67 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.76 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.86 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.87 rifampicin
rpoB 760323 c.517C>T synonymous_variant 0.88 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.88 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.88 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.87 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.87 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.85 rifampicin
rpoB 760343 c.537G>C synonymous_variant 0.85 rifampicin
rpoB 760357 p.Thr184Ser missense_variant 0.91 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.93 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.9 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.89 rifampicin Uncertain significance
rpoB 760412 c.606C>T synonymous_variant 0.9 rifampicin
rpoB 760415 c.609C>A synonymous_variant 0.9 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760496 c.690G>T synonymous_variant 0.84 rifampicin
rpoB 760508 c.702G>C synonymous_variant 0.83 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.8 rifampicin
rpoB 760521 p.Ser239Glu missense_variant 0.74 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Arg missense_variant 0.73 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760551 c.745_746delTCinsAG synonymous_variant 0.76 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.78 rifampicin Uncertain significance
rpoB 760571 c.765G>C synonymous_variant 0.8 rifampicin
rpoB 760574 c.768G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760591 p.Val262Ala missense_variant 0.83 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>T synonymous_variant 0.85 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.74 rifampicin
rpoB 760721 c.915C>G synonymous_variant 0.72 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760796 c.990A>G synonymous_variant 0.6 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.68 rifampicin
rpoB 760808 c.1002C>G synonymous_variant 0.68 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.68 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760842 c.1036_1038delCAGinsGC frameshift_variant&missense_variant 0.62 rifampicin
rpoB 760846 p.Thr347Lys missense_variant 0.62 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.73 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>T synonymous_variant 0.84 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.84 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.84 rifampicin Uncertain significance
rpoB 760916 c.1110C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.87 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.87 rifampicin Uncertain significance
rpoB 760973 c.1167G>C synonymous_variant 0.86 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.88 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.86 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.86 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.87 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>G synonymous_variant 0.76 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761156 c.1350G>C synonymous_variant 0.73 rifampicin
rpoB 761159 c.1353G>T synonymous_variant 0.73 rifampicin
rpoB 761160 c.1354C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.71 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.77 rifampicin
rpoB 761217 c.1411_1413delCCGinsTC frameshift_variant&missense_variant 0.76 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.74 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 0.71 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761274 c.1468C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.53 rifampicin
rpoB 761357 c.1551G>T synonymous_variant 0.53 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.53 rifampicin
rpoB 761366 c.1560C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761369 p.Glu521Asp missense_variant 0.5 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.53 rifampicin
rpoB 761384 c.1578C>G synonymous_variant 0.53 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.5 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761516 c.1710G>C synonymous_variant 0.52 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.68 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.75 rifampicin
rpoB 761603 c.1797C>G synonymous_variant 0.74 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.74 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761630 c.1824G>A synonymous_variant 0.71 rifampicin
rpoB 761636 c.1830G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.72 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.76 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.75 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.81 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.81 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.78 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.75 rifampicin
rpoB 761714 c.1908C>G synonymous_variant 0.74 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.63 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.69 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.69 rifampicin
rpoB 761753 c.1947C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761760 p.Ile652Val missense_variant 0.74 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.72 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.68 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.67 rifampicin
rpoB 761791 p.Arg662Gln missense_variant 0.73 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.72 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.74 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.8 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.8 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.81 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 0.8 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 0.79 rifampicin
rpoB 761881 p.Ala692Val missense_variant 0.78 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.82 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.8 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.79 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.78 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.79 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.79 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.86 rifampicin
rpoB 762000 c.2194_2195delTCinsAG synonymous_variant 0.86 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762068 c.2262C>T synonymous_variant 0.98 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.95 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.94 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.95 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.94 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.93 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.9 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 0.87 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.86 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 0.86 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.9 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.88 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.87 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.87 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.88 rifampicin
rpoB 762353 c.2547C>T synonymous_variant 0.88 rifampicin
rpoB 762359 c.2553C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 0.87 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.86 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.83 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.82 rifampicin
rpoC 762390 c.-980C>T upstream_gene_variant 0.82 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.8 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.79 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.79 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.85 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.92 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.95 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.95 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.94 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.94 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.94 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.93 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.79 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.77 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762818 c.3012C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762827 c.-543G>T upstream_gene_variant 0.9 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.92 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.88 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.87 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 0.89 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.9 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.89 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.89 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763217 c.-153G>C upstream_gene_variant 0.89 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.85 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.85 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.85 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 0.83 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.76 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.73 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.56 rifampicin
rpoC 763289 c.-81C>G upstream_gene_variant 0.56 rifampicin
rpoC 763373 c.4_6delCTCinsTA frameshift_variant&missense_variant 0.64 rifampicin
rpoC 763411 c.42T>C synonymous_variant 0.73 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.72 rifampicin
rpoC 763420 c.51G>C synonymous_variant 0.72 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.73 rifampicin Uncertain significance
rpoC 763429 c.60C>T synonymous_variant 0.73 rifampicin
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.73 rifampicin
rpoC 763435 c.66A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.87 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.91 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763711 c.342G>C synonymous_variant 0.87 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.87 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.88 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.87 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.87 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.82 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.8 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.82 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.8 rifampicin
rpoC 763822 c.453C>G synonymous_variant 0.79 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.76 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.73 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.7 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.61 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.5 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.5 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764023 c.654G>C synonymous_variant 0.59 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.57 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.61 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.58 rifampicin
rpoC 764044 c.675T>G synonymous_variant 0.62 rifampicin
rpoC 764054 c.685C>T synonymous_variant 0.7 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.74 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.75 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.75 rifampicin
rpoC 764101 c.732C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.74 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.69 rifampicin
rpoC 764143 c.774G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764147 p.Ser260Ala missense_variant 0.69 rifampicin Uncertain significance
rpoC 764153 p.Gln262Lys missense_variant 0.69 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.67 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.71 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Glu missense_variant 0.7 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.71 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.73 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.87 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.9 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.93 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764285 p.Gly306Ser missense_variant 0.92 rifampicin
rpoC 764317 c.948C>G synonymous_variant 0.95 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.95 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.92 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.92 rifampicin
rpoC 764405 c.1036_1038delAGGinsCT frameshift_variant&missense_variant 0.92 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764449 c.1080G>C synonymous_variant 0.92 rifampicin
rpoC 764452 c.1083T>G synonymous_variant 0.92 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.89 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.88 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.88 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 0.85 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.87 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764677 c.1308C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764680 c.1311G>A synonymous_variant 0.86 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.81 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.71 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 0.68 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.68 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.7 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.83 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.81 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.81 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.79 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.81 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.85 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.85 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.83 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765002 c.1633C>T synonymous_variant 0.83 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.82 rifampicin
rpoC 765022 c.1653G>C synonymous_variant 0.82 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.78 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>A synonymous_variant 0.76 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.82 rifampicin
rpoC 765371 c.2002C>T synonymous_variant 0.5 rifampicin
rpoC 765383 c.2014_2016delATGinsCC frameshift_variant&missense_variant 0.64 rifampicin
rpoC 765397 c.2028G>T synonymous_variant 0.8 rifampicin
rpoC 765405 p.Leu679His missense_variant 0.79 rifampicin Uncertain significance
rpoC 765409 c.2040T>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765425 p.Lys686Glu missense_variant 0.8 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.8 rifampicin
rpoC 765452 p.Ala695Arg missense_variant 0.79 rifampicin
rpoC 765458 p.Ile697Val missense_variant 0.8 rifampicin Uncertain significance
rpoC 765466 c.2097C>T synonymous_variant 0.83 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.83 rifampicin Uncertain significance
rpoC 765499 c.2130C>T synonymous_variant 0.84 rifampicin
rpoC 765544 c.2175C>G synonymous_variant 0.72 rifampicin
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.71 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.71 rifampicin
rpoC 765571 c.2202C>T synonymous_variant 0.68 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.64 rifampicin
rpoC 765591 p.Arg741Gln missense_variant 0.59 rifampicin
rpoC 765596 p.Lys743Gln missense_variant 0.57 rifampicin
rpoC 765607 c.2238C>G synonymous_variant 0.53 rifampicin
rpoC 765718 p.Asp783Glu missense_variant 0.42 rifampicin Uncertain significance
rpoC 765727 c.2358T>C synonymous_variant 0.47 rifampicin
rpoC 765728 p.Gln787Glu missense_variant 0.47 rifampicin
rpoC 765733 c.2364G>C synonymous_variant 0.5 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765741 p.Glu791Ala missense_variant 0.67 rifampicin Uncertain significance
rpoC 765751 c.2382C>G synonymous_variant 0.67 rifampicin
rpoC 765752 c.2383_2385delGACinsAG frameshift_variant&missense_variant 0.67 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.85 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.83 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.83 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.83 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.81 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765812 c.2443_2445delCGAinsAG frameshift_variant&synonymous_variant 0.8 rifampicin
rpoC 765817 c.2448G>A synonymous_variant 0.78 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.81 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.83 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.73 rifampicin
rpoC 765937 c.2568T>G synonymous_variant 0.72 rifampicin
rpoC 765946 c.2577C>T synonymous_variant 0.7 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 0.68 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.68 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765970 c.2601C>G synonymous_variant 0.68 rifampicin
rpoC 765973 c.2604C>G synonymous_variant 0.67 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 0.63 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>A synonymous_variant 0.59 rifampicin
rpoC 766018 c.2649C>T synonymous_variant 0.56 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.48 rifampicin
rpoC 766034 p.His889Thr missense_variant 0.38 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.27 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766351 c.2982C>G synonymous_variant 0.8 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.81 rifampicin
rpoC 766366 c.2997C>A synonymous_variant 0.81 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.81 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.93 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.88 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.88 rifampicin
rpoC 766423 c.3054T>C synonymous_variant 0.89 rifampicin
rpoC 766429 c.3060C>G synonymous_variant 0.87 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.87 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 0.89 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.88 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.88 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 0.88 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 0.88 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.88 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.86 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.89 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.87 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.86 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.89 rifampicin
rpoC 766568 p.Val1067Ile missense_variant 0.83 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.8 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.78 rifampicin
rpoC 766588 c.3219G>A synonymous_variant 0.74 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 766645 p.Glu1092Asp missense_variant 0.43 rifampicin Not assoc w R
rpoC 766651 c.3282T>C synonymous_variant 0.4 rifampicin
rpoC 766652 p.Ser1095Thr missense_variant 0.4 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.4 rifampicin
rpoC 766660 c.3291G>C synonymous_variant 0.38 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 0.44 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 0.5 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 0.55 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.55 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 766712 c.3343_3345delTCGinsGT frameshift_variant&missense_variant 0.66 rifampicin
rpoC 766735 c.3366G>A synonymous_variant 0.73 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.73 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.75 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.74 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.73 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.73 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>G synonymous_variant 0.72 rifampicin
rpoC 766861 c.3492G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766867 c.3498C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.72 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.72 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.71 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.71 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.74 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.76 rifampicin
rpoC 766920 p.Ala1184Gly missense_variant 0.79 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 0.79 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.89 rifampicin
rpoC 766951 c.3582G>C synonymous_variant 0.89 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766969 c.3600C>G synonymous_variant 0.92 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 0.86 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.86 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>T synonymous_variant 0.85 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.83 rifampicin
rpoC 767185 c.3816G>C synonymous_variant 0.82 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.82 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.85 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.79 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.77 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 767288 c.3919C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
mmpL5 775847 c.2634G>T synonymous_variant 0.65 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775856 c.2625T>C synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 775874 c.2607C>G synonymous_variant 0.55 clofazimine
bedaquiline
mmpL5 775880 p.Asn867Arg missense_variant 0.55 clofazimine
bedaquiline
mmpL5 775885 p.Ile866Val missense_variant 0.52 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 0.52 clofazimine
bedaquiline
mmpL5 775895 c.2584_2586delATCinsCG frameshift_variant&missense_variant 0.52 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775910 c.2571G>C synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 0.64 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>G synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 775922 c.2559G>A synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775975 p.Leu836Met missense_variant 0.85 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.84 clofazimine
bedaquiline
mmpL5 776000 c.2481G>C synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 776021 c.2458_2460delGTGinsAC frameshift_variant&missense_variant 0.88 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776029 c.2452C>T synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776030 c.2451G>T synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 776042 c.2439C>G synonymous_variant 0.62 clofazimine
bedaquiline
mmpL5 776045 c.2436G>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 776051 c.2428_2430delTTGinsAC frameshift_variant&missense_variant 0.52 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776063 c.2418C>T synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 777094 c.1387T>C synonymous_variant 0.57 clofazimine
bedaquiline
mmpL5 777095 c.1386T>C synonymous_variant 0.62 clofazimine
bedaquiline
mmpL5 777101 c.1380C>G synonymous_variant 0.59 clofazimine
bedaquiline
mmpL5 777107 c.1374T>C synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 777110 c.1371T>C synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777115 p.Met456Leu missense_variant 0.76 clofazimine
bedaquiline
mmpL5 777122 c.1359C>T synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 777133 p.Val450Ile missense_variant 0.79 clofazimine
bedaquiline
mmpL5 777142 p.Val447Leu missense_variant 0.74 clofazimine
bedaquiline
mmpL5 777143 c.1338G>A synonymous_variant 0.74 clofazimine
bedaquiline
mmpL5 777146 c.1335C>G synonymous_variant 0.74 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.64 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.64 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 0.64 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.66 clofazimine
bedaquiline
mmpL5 777182 c.1299C>T synonymous_variant 0.66 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.66 clofazimine
bedaquiline
mmpL5 777194 c.1285_1287delGAAinsCG frameshift_variant&missense_variant 0.68 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777206 c.1275A>G synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 777245 c.1236G>C synonymous_variant 0.55 clofazimine
bedaquiline
mmpL5 777254 c.1227G>C synonymous_variant 0.45 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.52 streptomycin
rpsL 781597 p.Arg13His missense_variant 0.52 streptomycin
rpsL 781605 p.Ile16Pro missense_variant 0.55 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.55 streptomycin
rpsL 781615 p.Val19Ala missense_variant 0.55 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.62 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.67 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.82 streptomycin
rpsL 781652 c.93T>C synonymous_variant 0.82 streptomycin
rpsL 781655 c.96T>A synonymous_variant 0.82 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.85 streptomycin
rpsL 781676 c.117C>G synonymous_variant 0.87 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.85 streptomycin
rpsL 781703 c.144G>A synonymous_variant 0.86 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.86 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.85 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.85 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.84 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.85 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.83 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.82 streptomycin
rpsL 781737 p.Gln60Ala missense_variant 0.82 streptomycin
rpsL 781751 c.192G>T synonymous_variant 0.85 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.86 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.88 streptomycin
rpsL 781772 c.213C>G synonymous_variant 0.89 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.86 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.85 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.85 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.85 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.88 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.89 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.88 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.87 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.89 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.89 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.9 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.91 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.91 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.92 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.92 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.91 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.46 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.54 linezolid
rplC 800537 c.-272C>G upstream_gene_variant 0.54 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.56 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.57 linezolid
rplC 800564 c.-245C>G upstream_gene_variant 0.55 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.54 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.54 linezolid
rplC 800577 c.-232_-230delCGCinsAA upstream_gene_variant 0.54 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.53 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.53 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 0.53 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.55 linezolid
rplC 800603 c.-206G>A upstream_gene_variant 0.55 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.61 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.64 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.66 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.67 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.67 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.7 linezolid
rplC 800693 c.-116A>T upstream_gene_variant 0.82 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.8 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.8 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.8 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.8 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.8 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.78 linezolid
rplC 801174 c.366T>C synonymous_variant 0.57 linezolid
rplC 801186 c.378C>G synonymous_variant 0.76 linezolid
rplC 801195 c.387G>C synonymous_variant 0.73 linezolid
rplC 801207 c.399C>T synonymous_variant 0.75 linezolid
rplC 801210 c.402T>C synonymous_variant 0.75 linezolid
rplC 801222 c.414T>C synonymous_variant 0.74 linezolid
rplC 801228 c.420T>C synonymous_variant 0.75 linezolid
rplC 801237 c.429G>C synonymous_variant 0.77 linezolid
rplC 801252 c.444G>C synonymous_variant 0.8 linezolid
rplC 801258 c.450C>G synonymous_variant 0.78 linezolid
rplC 801267 c.459A>C synonymous_variant 0.78 linezolid
rplC 801270 c.462T>C synonymous_variant 0.76 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.75 linezolid
rplC 801307 p.Ala167Ser missense_variant 0.78 linezolid
rplC 801312 c.504G>C synonymous_variant 0.78 linezolid
rplC 801315 c.507G>C synonymous_variant 0.75 linezolid
rplC 801324 c.516T>C synonymous_variant 0.76 linezolid
rplC 801330 c.522G>T synonymous_variant 0.72 linezolid
rplC 801336 c.528C>G synonymous_variant 0.65 linezolid
rplC 801337 p.Val177Thr missense_variant 0.63 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.61 linezolid
rplC 801348 c.540T>G synonymous_variant 0.63 linezolid
rplC 801357 c.549T>C synonymous_variant 0.59 linezolid
rplC 801369 c.561C>T synonymous_variant 0.63 linezolid
rplC 801387 c.579G>C synonymous_variant 0.48 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
Rv1129c 1254582 c.-48A>G upstream_gene_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiC 1303789 p.Ile287Val missense_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303827 p.Glu299Asp missense_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303857 c.927C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303861 p.Ile311Phe missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 0.73 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303871 p.Tyr314Phe missense_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303891 p.Ala321Thr missense_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303903 p.Leu325Met missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303908 c.978C>A synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303912 p.Gly328Lys missense_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>A synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304007 c.1077G>A synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>T synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304046 c.1116C>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304055 p.Asp375Glu missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304059 c.1129C>T synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304082 c.1152C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304101 c.1171C>A synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304106 c.1176G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304109 c.1179C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304151 c.1221C>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>A synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304667 c.1737G>A synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1304682 c.1752C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304712 c.1782C>G synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.69 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.5 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304775 c.1845C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304793 c.1863C>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.57 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305231 c.2301C>A synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 0.38 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305291 c.2361C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305318 c.2388C>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305351 c.2421G>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
Rv1258c 1406297 c.1044A>G synonymous_variant 0.6 streptomycin
isoniazid
pyrazinamide
Rv1258c 1406318 c.1021_1023delGCAinsCG frameshift_variant&synonymous_variant 0.56 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
embR 1416666 p.Tyr228His missense_variant 1.0 ethambutol Uncertain significance
embR 1417554 c.-207C>G upstream_gene_variant 1.0 ethambutol
atpE 1461071 c.27C>G synonymous_variant 0.55 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.69 bedaquiline
atpE 1461107 c.63C>A synonymous_variant 0.71 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 0.71 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.71 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.69 bedaquiline
atpE 1461146 c.102G>C synonymous_variant 0.71 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.71 bedaquiline
atpE 1461153 p.Ser37Ala missense_variant 0.71 bedaquiline Uncertain significance
atpE 1461158 c.114T>C synonymous_variant 0.73 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.73 bedaquiline Uncertain significance
atpE 1461167 c.123G>C synonymous_variant 0.76 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.76 bedaquiline
atpE 1461179 c.135G>T synonymous_variant 0.67 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.67 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.67 bedaquiline
atpE 1461188 c.144G>A synonymous_variant 0.67 bedaquiline
atpE 1461197 c.153A>T synonymous_variant 0.62 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 0.57 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.57 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.57 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.5 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472022 n.178_181delGGAC non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185_188delGGGAinsCTCTTTGGT non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>A non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472042 n.197T>C non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472048 n.203T>G non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472298 n.453_468delGTCCGGGTTCTCTCGGinsCGTA non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1473813 n.156C>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474287 n.630T>C non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474288 n.632_633insGC non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474292 n.636_647delTCCTCTCCGGAG non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.654_655dupGG non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474415 n.759_769delCACACGCGCAT non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474430 n.773delCinsTCAGTGGTG non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAGT non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475375 n.1718G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475376 n.1719A>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid Uncertain significance
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475396 n.1739C>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475406 n.1749T>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475407 n.1750C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475707 n.2050T>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475762 n.2105G>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476119 n.2462G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476691 n.3034T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
inhA 1673514 c.-688G>C upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1673517 c.-685G>C upstream_gene_variant 0.55 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.55 ethionamide
isoniazid
inhA 1673544 c.-658G>C upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.67 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673586 c.-616C>A upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673589 c.-613A>G upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673592 c.-610G>A upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673596 c.157_159delAAGinsGC frameshift_variant&missense_variant 0.84 ethionamide
isoniazid
inhA 1673601 c.-601G>T upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673613 c.-589C>G upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673614 c.175_177delGAAinsCG frameshift_variant&missense_variant 0.84 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.89 ethionamide
isoniazid
inhA 1673643 c.-559C>A upstream_gene_variant 0.89 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.87 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.76 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.82 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673700 c.-502C>G upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673784 c.-418G>A upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.82 ethionamide
isoniazid
inhA 1673805 c.-397G>C upstream_gene_variant 0.82 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 0.83 ethionamide
isoniazid
fabG1 1673830 p.Lys131Arg missense_variant 0.83 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 0.83 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 0.83 ethionamide
isoniazid
fabG1 1673844 p.Met135Ile missense_variant 0.81 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 0.81 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 0.78 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 0.79 ethionamide
isoniazid
inhA 1673883 c.-319C>T upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.83 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.79 ethionamide
isoniazid
inhA 1673916 c.-286A>G upstream_gene_variant 0.76 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.76 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.68 ethionamide
isoniazid
inhA 1673937 c.-265G>A upstream_gene_variant 0.44 ethionamide
isoniazid
inhA 1674416 p.Ala72Asp missense_variant 0.5 ethionamide
isoniazid
inhA 1674418 c.217_218delAGinsTC synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674428 p.Gly76Asp missense_variant 0.5 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674443 p.Ala81Val missense_variant 0.76 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 0.77 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 0.77 ethionamide
isoniazid
inhA 1674455 p.Gly85Asp missense_variant 0.76 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674474 c.273G>C synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674491 p.Phe97Tyr missense_variant 0.82 ethionamide
isoniazid
inhA 1674502 c.301_303delACCinsTG frameshift_variant&missense_variant 0.79 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674542 p.Ala114Asp missense_variant 0.81 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.79 ethionamide
isoniazid
inhA 1674561 c.360C>T synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.74 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.75 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.73 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.73 ethionamide
isoniazid
inhA 1674601 c.400C>T synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674604 c.403C>T synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674609 c.408G>C synonymous_variant 0.68 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 0.64 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 0.62 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.58 ethionamide
isoniazid
inhA 1674658 c.457C>A synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 0.52 ethionamide
isoniazid
inhA 1674693 c.492C>T synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674699 c.498C>T synonymous_variant 0.47 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 0.44 ethionamide
isoniazid
rpsA 1833547 c.6G>A synonymous_variant 0.53 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.58 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.73 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.73 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.81 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.82 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.86 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.87 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.89 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.88 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.9 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.92 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.89 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.88 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.88 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.88 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.89 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.85 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.86 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.87 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.86 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.86 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.91 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.91 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.86 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.84 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.85 pyrazinamide
rpsA 1833901 c.360G>A synonymous_variant 0.85 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.86 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.85 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.84 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.87 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.87 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834090 c.549G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.74 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834282 c.741C>T synonymous_variant 0.84 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.84 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.88 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834360 c.819G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.89 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834423 c.882G>A synonymous_variant 0.92 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.93 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.93 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 0.93 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834531 c.990C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.87 pyrazinamide
rpsA 1834556 p.Ala339Gln missense_variant 0.87 pyrazinamide
rpsA 1834598 c.1057C>T synonymous_variant 0.82 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGT synonymous_variant 0.79 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.78 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.83 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.83 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 0.78 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.78 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.76 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.76 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.76 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.76 pyrazinamide
rpsA 1834787 c.1246_1248delGCTinsTG frameshift_variant&missense_variant 0.76 pyrazinamide Uncertain significance
rpsA 1834792 c.1251G>T synonymous_variant 0.76 pyrazinamide
rpsA 1834798 c.1257C>G synonymous_variant 0.76 pyrazinamide
rpsA 1834834 c.1293G>A synonymous_variant 0.67 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.79 linezolid
tsnR 1853370 c.-236_-234delGCAinsTT upstream_gene_variant 0.8 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 0.8 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.85 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.85 linezolid
tsnR 1853390 c.-216G>A upstream_gene_variant 0.83 linezolid
tsnR 1853394 c.-212_-210delCTCinsGCG upstream_gene_variant 0.82 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.69 linezolid
tsnR 1853429 c.-177G>A upstream_gene_variant 0.67 linezolid
tsnR 1853430 c.-176C>T upstream_gene_variant 0.64 linezolid
tsnR 1853444 c.-162C>G upstream_gene_variant 0.57 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.5 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.48 linezolid
tsnR 1853474 c.-132C>G upstream_gene_variant 0.32 linezolid
tsnR 1853669 p.Arg22Cys missense_variant 1.0 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
bacA 2064438 c.291G>A synonymous_variant 1.0 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
bacA 2064993 c.-265T>C upstream_gene_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155503 c.609C>T synonymous_variant 1.0 isoniazid Not assoc w R
katG 2155641 p.Lys157Asn missense_variant 0.36 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 0.46 isoniazid
katG 2155674 c.438G>C synonymous_variant 0.48 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.5 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.59 isoniazid
katG 2155716 c.396T>C synonymous_variant 0.55 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.55 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.55 isoniazid
katG 2155735 p.Met126Ala missense_variant 0.55 isoniazid
katG 2155740 p.Gly124Glu missense_variant 0.52 isoniazid
katG 2155743 c.369G>T synonymous_variant 0.5 isoniazid
katG 2155746 c.366C>G synonymous_variant 0.5 isoniazid
katG 2155765 p.His116Phe missense_variant 0.44 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.33 isoniazid
PPE35 2168011 p.Ser868Arg missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2168319 p.Thr765Ile missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
kasA 2517941 c.-174C>G upstream_gene_variant 0.81 isoniazid
kasA 2517962 c.-153C>T upstream_gene_variant 0.74 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.65 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.6 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.45 isoniazid
kasA 2518150 c.36C>G synonymous_variant 0.48 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.48 isoniazid
kasA 2518156 c.42T>C synonymous_variant 0.52 isoniazid
kasA 2518159 c.45G>C synonymous_variant 0.52 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.59 isoniazid
kasA 2518180 c.66G>C synonymous_variant 0.63 isoniazid
kasA 2518187 p.Ile25Val missense_variant 0.59 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.59 isoniazid
kasA 2518193 p.Pro27Ala missense_variant 0.59 isoniazid
kasA 2518219 c.105T>G synonymous_variant 0.67 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.67 isoniazid
kasA 2518223 c.109T>C synonymous_variant 0.67 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.67 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.63 isoniazid
kasA 2518255 c.141A>G synonymous_variant 0.53 isoniazid
kasA 2518273 c.159G>A synonymous_variant 0.48 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.47 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.47 isoniazid
kasA 2518759 c.645C>G synonymous_variant 0.47 isoniazid
kasA 2518769 p.Arg219Asn missense_variant 0.47 isoniazid
kasA 2518777 p.Asp221Glu missense_variant 0.41 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.39 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.39 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.39 isoniazid
kasA 2518787 c.673_675delCGGinsGC frameshift_variant&missense_variant 0.38 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.39 isoniazid
kasA 2518811 p.Asp233Asn missense_variant 0.46 isoniazid
kasA 2518822 c.708C>T synonymous_variant 0.5 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.5 isoniazid
kasA 2518828 c.714G>C synonymous_variant 0.52 isoniazid
kasA 2518849 c.735G>C synonymous_variant 0.57 isoniazid
kasA 2518853 p.Leu247Val missense_variant 0.57 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.5 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.39 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.72 isoniazid
ahpC 2726642 c.450C>T synonymous_variant 0.72 isoniazid
ahpC 2726648 c.456T>G synonymous_variant 0.71 isoniazid
ahpC 2726651 c.459G>T synonymous_variant 0.71 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 0.65 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.65 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.61 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.62 isoniazid
Rv2477c 2782398 c.1645A>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782399 c.1644T>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782405 c.1638A>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782408 c.1635T>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782414 p.Asp543Glu missense_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782419 p.Val542Ile missense_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782426 c.1617G>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782429 c.1614A>G synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>T synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782486 c.1557G>A synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782494 p.Asp517His missense_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 p.Asp516Glu missense_variant 0.76 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782537 c.1506T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782576 c.1467C>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782867 c.1174_1176delGCCinsTG frameshift_variant&missense_variant 0.56 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782894 c.1149C>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782897 p.Glu382Asp missense_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782909 c.1134C>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782913 p.Ser377Thr missense_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782924 c.1119G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782945 c.1098C>G synonymous_variant 0.7 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783005 c.1038C>A synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783010 c.1032delG frameshift_variant 0.68 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783015 c.1027_1028insC frameshift_variant 0.65 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783026 c.1017C>T synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783038 c.1003_1005delGCCinsAG frameshift_variant&missense_variant 0.67 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783048 p.Asp332Gly missense_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783053 c.990C>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783071 c.972C>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783080 c.963G>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Val missense_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783296 c.747C>A synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783308 c.735G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783338 c.705C>T synonymous_variant 0.61 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783413 c.630G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783431 p.Ser204Glu missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783434 c.609C>G synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.76 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783520 c.523T>C synonymous_variant 0.74 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783551 c.492G>A synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783554 c.489C>T synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783578 c.465G>A synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783584 c.457_459delGCCinsCG frameshift_variant&synonymous_variant 0.73 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783593 c.450T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783602 c.441G>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783617 c.426G>A synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783827 c.216C>T synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783856 p.Phe63Leu missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>T synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783877 p.Lys56Gln missense_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>A synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783917 c.126C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783926 c.117C>T synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859747 c.672C>G synonymous_variant 0.39 clofazimine
bedaquiline
pepQ 2859756 c.663C>T synonymous_variant 0.35 clofazimine
bedaquiline
pepQ 2859771 c.648T>C synonymous_variant 0.35 clofazimine
bedaquiline
pepQ 2859792 c.627C>T synonymous_variant 0.35 clofazimine
bedaquiline
thyX 3067309 p.Ile213Val missense_variant 0.5 para-aminosalicylic_acid
thyX 3067316 c.630A>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067319 c.627G>C synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067328 c.618G>C synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067394 c.552G>A synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067403 c.543C>G synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067418 c.528C>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067430 c.516C>T synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067433 c.513C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067445 c.501C>T synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067760 c.186G>C synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.43 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 0.57 para-aminosalicylic_acid
thyX 3067790 c.156C>A synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067796 c.150C>G synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067808 c.138C>T synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067862 c.84C>T synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.53 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067880 p.Asp22Glu missense_variant 0.54 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3073860 c.612C>T synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073887 c.583_585delTCGinsAC frameshift_variant&missense_variant 0.67 para-aminosalicylic_acid
thyA 3073891 p.Leu194Ser missense_variant 0.69 para-aminosalicylic_acid
thyA 3073893 c.578dupG frameshift_variant 0.71 para-aminosalicylic_acid
thyA 3073950 c.522G>A synonymous_variant 0.78 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073965 c.507C>T synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073992 c.478_480delAGCinsTCG synonymous_variant 0.68 para-aminosalicylic_acid
thyA 3073995 c.477G>C synonymous_variant 0.68 para-aminosalicylic_acid
thyA 3074000 c.472C>A synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3074013 c.459C>T synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3074193 c.277_279delATCinsGA frameshift_variant&missense_variant 0.44 para-aminosalicylic_acid
thyA 3074199 c.273G>C synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.42 para-aminosalicylic_acid
thyA 3074214 p.Asp86Glu missense_variant 0.42 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074241 c.231C>G synonymous_variant 0.44 para-aminosalicylic_acid
lpqB 3623730 p.Ser394Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624486 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625168 c.-258G>T upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625174 c.-264C>T upstream_gene_variant 0.57 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.54 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.54 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.43 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625669 c.-759G>C upstream_gene_variant 0.3 bedaquiline
rifampicin
mtrB 3625678 c.936C>A synonymous_variant 0.4 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625687 c.-777G>C upstream_gene_variant 0.48 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625693 c.-783G>C upstream_gene_variant 0.48 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.76 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3625766 p.Ser283His missense_variant 0.77 bedaquiline
rifampicin
mtrB 3625774 c.840G>A synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625796 p.Val273Glu missense_variant 0.75 bedaquiline
rifampicin
lpqB 3625798 c.-888G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
lpqB 3625801 c.-891G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625825 c.-915C>T upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625840 c.-930A>G upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 0.57 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.43 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 0.43 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625882 c.732G>A synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626476 c.138C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrA 3626699 c.651C>T synonymous_variant 0.63 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3626711 p.Thr213Gln missense_variant 0.7 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626735 c.-122C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 0.79 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 0.77 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626798 c.-185T>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrA 3626864 c.484_486delTTGinsCC frameshift_variant&missense_variant 0.79 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrA 3626907 p.Asn148Leu missense_variant 0.67 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626921 c.-308C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3626924 c.-311G>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626930 c.-317A>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrA 3626949 p.Ala134Gly missense_variant 0.75 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3626966 c.-353C>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.58 bedaquiline
rifampicin Uncertain significance
mtrB 3626992 c.-379C>T upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3626999 c.-386G>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3627005 c.-392G>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3627014 c.-401G>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3627017 c.-404G>A upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3627035 c.-422G>A upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.75 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.47 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3627158 c.-545C>G upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrA 3627185 c.163_165delTTGinsCC frameshift_variant&missense_variant 0.59 bedaquiline
rifampicin
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.59 bedaquiline
rifampicin
mtrB 3627197 c.-584T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3627215 c.-602G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627224 c.-611G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627233 c.-620T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627263 c.-650C>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrA 3627307 p.Ala15Pro missense_variant 0.73 bedaquiline
rifampicin
mtrA 3627311 c.39C>T synonymous_variant 0.68 bedaquiline Not assoc w R - Interim
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3627320 c.-707C>G upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627325 c.-712T>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.57 bedaquiline
rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.45 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 0.45 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 0.45 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 0.47 rifampicin
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 0.53 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.93 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.93 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>T synonymous_variant 0.92 rifampicin
rpoA 3877685 c.823C>T synonymous_variant 0.92 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.93 rifampicin
rpoA 3877728 c.780C>G synonymous_variant 0.89 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 0.9 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 0.88 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.84 rifampicin
rpoA 3877803 c.705G>C synonymous_variant 0.84 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877841 c.667C>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>G synonymous_variant 0.84 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 0.84 rifampicin
rpoA 3877865 c.643C>T synonymous_variant 0.83 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>A synonymous_variant 0.83 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.82 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 0.82 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.88 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.87 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.88 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878010 c.498C>G synonymous_variant 0.91 rifampicin
rpoA 3878019 c.489A>G synonymous_variant 0.88 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.88 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.88 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.88 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.88 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>G synonymous_variant 0.88 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.88 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.88 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.84 rifampicin
rpoA 3878064 c.444G>C synonymous_variant 0.86 rifampicin
rpoA 3878067 c.441C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878070 c.438T>C synonymous_variant 0.84 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.88 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.86 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.87 rifampicin
rpoA 3878118 p.Asp130Glu missense_variant 0.83 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 0.85 rifampicin
rpoA 3878142 p.Gly122Glu missense_variant 0.81 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.81 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878166 c.342C>G synonymous_variant 0.83 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>T synonymous_variant 0.84 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.84 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.91 rifampicin
rpoA 3878250 c.258C>G synonymous_variant 0.9 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.88 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.85 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.83 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>T synonymous_variant 0.77 rifampicin
rpoA 3878307 c.201C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878316 c.192C>G synonymous_variant 0.75 rifampicin
rpoA 3878322 c.186A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.69 rifampicin
rpoA 3878358 c.150C>G synonymous_variant 0.59 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.59 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.62 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.58 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.44 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3878394 c.114G>T synonymous_variant 0.47 rifampicin
rpoA 3878869 c.-362G>T upstream_gene_variant 0.74 rifampicin
rpoA 3878881 c.-374C>G upstream_gene_variant 0.74 rifampicin
rpoA 3878886 c.-379G>A upstream_gene_variant 0.74 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 0.74 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 0.74 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.75 rifampicin
rpoA 3878909 c.-403_-402delAAinsCT upstream_gene_variant 0.75 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.77 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.77 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.76 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 0.73 rifampicin
rpoA 3878965 c.-458C>A upstream_gene_variant 0.74 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.74 rifampicin Uncertain significance
rpoA 3879061 c.-554C>T upstream_gene_variant 0.54 rifampicin
rpoA 3879070 c.-563G>A upstream_gene_variant 0.67 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.71 rifampicin
rpoA 3879082 c.-575C>A upstream_gene_variant 0.71 rifampicin
rpoA 3879088 c.-583_-581delACAinsTC upstream_gene_variant 0.74 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.78 rifampicin
rpoA 3879121 c.-616_-614delCTTinsTG upstream_gene_variant 0.71 rifampicin
rpoA 3879124 c.-618_-617delTGinsGT upstream_gene_variant 0.77 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.77 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.77 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.71 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.71 rifampicin
ddn 3986622 c.-222C>T upstream_gene_variant 0.8 delamanid
pretomanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.69 delamanid
pretomanid
ddn 3986646 c.-198_-196delCTCinsTG upstream_gene_variant 0.68 delamanid
pretomanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.59 delamanid
pretomanid
clpC1 4038325 p.Val794Ile missense_variant 0.41 pyrazinamide
clpC1 4038335 c.2370C>G synonymous_variant 0.47 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.63 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.67 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038377 c.2328C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.64 pyrazinamide
clpC1 4038395 c.2310C>G synonymous_variant 0.64 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 0.64 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCC frameshift_variant&missense_variant 0.64 pyrazinamide
clpC1 4038410 c.2295C>T synonymous_variant 0.69 pyrazinamide
clpC1 4038416 c.2289C>A synonymous_variant 0.72 pyrazinamide
clpC1 4038419 c.2286T>A synonymous_variant 0.72 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.64 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.61 pyrazinamide
clpC1 4038449 c.2256C>G synonymous_variant 0.61 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.61 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.61 pyrazinamide
clpC1 4038461 c.2242_2244delGCGinsTC frameshift_variant&missense_variant 0.61 pyrazinamide
clpC1 4038474 p.Ser744Thr missense_variant 0.76 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.83 pyrazinamide
clpC1 4038490 p.Ala739Ser missense_variant 0.83 pyrazinamide
clpC1 4038491 c.2214C>G synonymous_variant 0.85 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.84 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.89 pyrazinamide
clpC1 4038533 c.2172C>T synonymous_variant 0.89 pyrazinamide
clpC1 4038587 c.2118C>A synonymous_variant 0.95 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.89 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.84 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038650 c.2055C>T synonymous_variant 0.81 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.78 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.76 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038668 c.2037G>C synonymous_variant 0.76 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.71 pyrazinamide
clpC1 4038683 c.2020_2022delTCTinsAGC synonymous_variant 0.75 pyrazinamide
clpC1 4038695 c.2010C>G synonymous_variant 0.76 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.76 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.76 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038746 c.1959C>T synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4038749 c.1956C>T synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>C synonymous_variant 0.74 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.75 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 0.89 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.88 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.85 pyrazinamide
clpC1 4038860 c.1845G>T synonymous_variant 0.84 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 0.86 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.84 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.83 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.84 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.83 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038935 c.1770C>G synonymous_variant 0.86 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.85 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.85 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039088 c.1617G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039094 c.1611C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039115 c.1590G>A synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039121 c.1584T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039166 c.1539G>A synonymous_variant 0.9 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.9 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.92 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 0.9 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.87 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4039328 c.1377A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.8 pyrazinamide
clpC1 4039347 p.Arg453Lys missense_variant 0.79 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.93 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.89 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.89 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.91 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039457 c.1248C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.87 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039472 c.1233G>A synonymous_variant 0.88 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039553 c.1152C>A synonymous_variant 0.9 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 0.9 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039592 c.1113G>T synonymous_variant 0.9 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.91 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039616 c.1089G>T synonymous_variant 0.92 pyrazinamide
clpC1 4039622 c.1083C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039640 c.1065C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039655 c.1050G>T synonymous_variant 0.91 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.84 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.88 pyrazinamide
clpC1 4039799 c.906C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.87 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.84 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039844 c.861C>T synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 0.87 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.79 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.78 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039942 c.763C>T synonymous_variant 0.8 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.8 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039988 c.717C>T synonymous_variant 0.87 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040033 c.672G>T synonymous_variant 0.9 pyrazinamide
clpC1 4040051 c.654C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.88 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.81 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040135 c.570C>G synonymous_variant 0.79 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.73 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.68 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>A synonymous_variant 0.68 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.68 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.68 pyrazinamide
clpC1 4040189 c.516C>T synonymous_variant 0.64 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.62 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.59 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.59 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.59 pyrazinamide
clpC1 4040213 p.Ser164Asn missense_variant 0.64 pyrazinamide
clpC1 4040221 p.Ser162Ala missense_variant 0.64 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.67 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040243 c.462C>G synonymous_variant 0.72 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 0.71 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.68 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040270 c.435C>T synonymous_variant 0.7 pyrazinamide
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.67 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040300 c.405C>T synonymous_variant 0.74 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.73 pyrazinamide
clpC1 4040315 c.390G>A synonymous_variant 0.67 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.57 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040342 c.363C>T synonymous_variant 0.57 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.57 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.57 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.5 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 0.53 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.5 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.55 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.59 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.57 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.63 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.67 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.67 pyrazinamide
clpC1 4040438 c.267G>A synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040441 c.264C>G synonymous_variant 0.6 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.6 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.62 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.52 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.52 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.54 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>A synonymous_variant 0.54 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.4 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.42 pyrazinamide
clpC1 4040615 c.90C>A synonymous_variant 0.4 pyrazinamide
clpC1 4040618 c.87C>A synonymous_variant 0.4 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.42 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.45 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.45 pyrazinamide
clpC1 4040690 c.15T>C synonymous_variant 0.41 pyrazinamide
panD 4044093 c.189A>G synonymous_variant 0.57 pyrazinamide
panD 4044108 c.174C>T synonymous_variant 0.62 pyrazinamide
panD 4044111 c.171C>G synonymous_variant 0.62 pyrazinamide
panD 4044120 c.162A>G synonymous_variant 0.65 pyrazinamide
panD 4044123 c.159T>A synonymous_variant 0.65 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
panD 4044144 c.138C>T synonymous_variant 0.68 pyrazinamide
panD 4044147 c.135C>G synonymous_variant 0.65 pyrazinamide
panD 4044150 c.132A>G synonymous_variant 0.65 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
panD 4044159 c.123C>T synonymous_variant 0.72 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 0.68 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.68 pyrazinamide
panD 4044168 c.114G>T synonymous_variant 0.68 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.78 pyrazinamide
panD 4044192 c.90C>G synonymous_variant 0.75 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.75 pyrazinamide
panD 4044213 c.69C>G synonymous_variant 0.67 pyrazinamide
glpK 4138580 c.1176C>T synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>T synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138628 c.1128T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>T synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138649 c.1107C>T synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138654 c.1102C>T synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138655 c.1101G>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138661 c.1095T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138664 c.1092G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138667 c.1089G>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>T synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138695 p.Pro354Asp missense_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138700 c.1056G>A synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138745 c.1011G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138751 c.1005T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138775 c.981C>G synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138781 c.975G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139282 c.474T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139285 p.Glu157Asp missense_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139302 p.Leu152Val missense_variant 0.78 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139312 c.444T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139318 c.438T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139321 c.435T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139324 c.432A>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139339 c.417G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139348 c.408C>G synonymous_variant 0.86 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139356 p.Leu134Val missense_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139359 p.Asn133Asp missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139360 c.396A>T synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139363 c.393T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139366 c.390T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139372 c.384A>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139375 c.381T>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139378 c.378G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139386 p.Ser124Thr missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139408 c.348T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139417 c.339A>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139420 c.336T>C synonymous_variant 0.84 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139435 c.321C>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139440 c.316C>A synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139441 c.315A>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139447 p.His103Arg missense_variant 0.62 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139459 c.297A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139467 p.Thr97Ala missense_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240717 c.855T>C synonymous_variant 0.83 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embC 4240736 p.Ser292Ala missense_variant 0.88 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.77 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.77 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.77 ethambutol
embC 4240807 c.945C>G synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embC 4240822 c.960C>G synonymous_variant 0.73 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.72 ethambutol
embC 4240867 c.1005T>G synonymous_variant 0.42 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.44 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.33 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.43 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.45 ethambutol
embC 4241053 c.1191G>T synonymous_variant 0.48 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.5 ethambutol
embC 4241071 c.1209C>G synonymous_variant 0.48 ethambutol
embC 4241072 p.Leu404Val missense_variant 0.5 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.52 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.57 ethambutol
embC 4241109 p.Ala416Gly missense_variant 0.6 ethambutol
embC 4241116 c.1254C>G synonymous_variant 0.6 ethambutol
embC 4241131 c.1269G>T synonymous_variant 0.58 ethambutol
embC 4241137 c.1275G>C synonymous_variant 0.58 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.56 ethambutol
embC 4241147 p.Cys429Ile missense_variant 0.56 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.53 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4241162 c.1300_1302delTTGinsCC frameshift_variant&missense_variant 0.5 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242970 c.3108C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244220 c.988C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4246551 p.Asn13Ser missense_variant 1.0 ethambutol Not assoc w R
embB 4246864 c.351C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247434 c.921C>G synonymous_variant 0.46 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embB 4247455 c.942C>T synonymous_variant 0.47 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.53 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.53 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.5 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.46 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.43 ethambutol
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
embB 4248085 c.1572T>C synonymous_variant 0.46 ethambutol
embB 4248094 c.1581C>T synonymous_variant 0.51 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.51 ethambutol
embB 4248098 p.Ile529Phe missense_variant 0.51 ethambutol
embB 4248106 c.1593C>G synonymous_variant 0.54 ethambutol
embB 4248109 c.1596C>A synonymous_variant 0.55 ethambutol
embB 4248112 c.1599C>G synonymous_variant 0.57 ethambutol
embB 4248127 c.1614G>A synonymous_variant 0.66 ethambutol Not assoc w R - Interim
embB 4248142 c.1629T>C synonymous_variant 0.67 ethambutol
embB 4248145 p.Leu544Phe missense_variant 0.67 ethambutol
embB 4248155 c.1642_1644delCTAinsTG frameshift_variant&stop_gained 0.65 ethambutol
embB 4248159 p.Cys549Ser missense_variant 0.64 ethambutol
embB 4248169 c.1656C>G synonymous_variant 0.67 ethambutol
embB 4248170 p.Ala553Ser missense_variant 0.67 ethambutol
embB 4248173 p.Val554Met missense_variant 0.69 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.77 ethambutol
embB 4248206 c.1693_1695delAGCinsGG frameshift_variant&missense_variant 0.77 ethambutol
embB 4248220 c.1707A>T synonymous_variant 0.79 ethambutol
embB 4248226 c.1713G>C synonymous_variant 0.77 ethambutol
embB 4248242 p.Val577Ile missense_variant 0.73 ethambutol
embB 4248248 p.Phe579Leu missense_variant 0.73 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.7 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 0.41 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.46 ethambutol
aftB 4269048 c.-212C>T upstream_gene_variant 0.45 ethambutol
ubiA 4269071 p.Phe255Ile missense_variant 0.52 ethambutol
aftB 4269075 c.-239T>C upstream_gene_variant 0.52 ethambutol
ubiA 4269078 p.Met252Ile missense_variant 0.5 ethambutol
ubiA 4269083 p.Ser251Thr missense_variant 0.5 ethambutol
aftB 4269084 c.-248G>C upstream_gene_variant 0.5 ethambutol
ubiA 4269090 p.Phe248Tyr missense_variant 0.52 ethambutol
aftB 4269096 c.-260C>G upstream_gene_variant 0.52 ethambutol
ubiA 4269100 p.Gly245Ala missense_variant 0.53 ethambutol
ubiA 4269103 p.Ser244Thr missense_variant 0.55 ethambutol
ubiA 4269106 p.Tyr243Ala missense_variant 0.55 ethambutol
aftB 4269114 c.-278C>T upstream_gene_variant 0.62 ethambutol
aftB 4269117 c.-281G>A upstream_gene_variant 0.67 ethambutol
aftB 4269123 c.-287T>C upstream_gene_variant 0.69 ethambutol
ubiA 4269141 c.691_693delTTGinsCC frameshift_variant&missense_variant 0.66 ethambutol
aftB 4269144 c.-308C>T upstream_gene_variant 0.67 ethambutol
ubiA 4269149 p.Val229Met missense_variant 0.69 ethambutol
aftB 4269171 c.-335C>G upstream_gene_variant 0.67 ethambutol
aftB 4269177 c.-341G>C upstream_gene_variant 0.64 ethambutol
ubiA 4269188 p.Thr216Ser missense_variant 0.63 ethambutol Uncertain significance
ubiA 4269189 p.Ser215Ala missense_variant 0.64 ethambutol
aftB 4269192 c.-356C>G upstream_gene_variant 0.61 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.67 ethambutol
aftB 4269207 c.-371G>C upstream_gene_variant 0.67 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.63 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.61 ethambutol Not assoc w R - Interim
aftB 4269240 c.-404G>C upstream_gene_variant 0.59 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.59 ethambutol
aftB 4269249 c.-413G>A upstream_gene_variant 0.59 ethambutol
aftB 4269252 c.-416C>G upstream_gene_variant 0.61 ethambutol
aftB 4269258 c.-422C>T upstream_gene_variant 0.58 ethambutol
aftB 4269264 c.-428C>A upstream_gene_variant 0.57 ethambutol
ubiA 4269351 c.483C>T synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
aftB 4269399 c.-563A>G upstream_gene_variant 0.35 ethambutol
aftB 4269405 c.-569G>A upstream_gene_variant 0.33 ethambutol
aftB 4269411 c.-575T>G upstream_gene_variant 0.35 ethambutol
aftB 4269414 c.-578T>C upstream_gene_variant 0.38 ethambutol
aftB 4269435 c.-599C>G upstream_gene_variant 0.4 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin