TB-Profiler result

Run: ERR1873492

Summary

Run ID: ERR1873492

Sample name:

Date: 2024-04-14T09:28:59.021135

Number of reads: 1044181

Percentage reads mapped: 30.32

Median coverage: 19.0

Strain: M.canetti;lineage2.2.2;lineage6.2

Spoligotype:

Drug-resistance: HR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.2 West-Africa 2 RD702 0.08
lineage2 East-Asian RD105 0.93
La1.2.BCG M.bovis None 0.17
lineage2.2.2 East-Asian (Beijing) RD105;RD207 0.64
lineage2.2 East-Asian (Beijing) RD105;RD207 0.97
M.canetti M.canetti None 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
c.451_453delGTCinsCG Assoc w R High-level resistance
ethambutol embB p.Met306Ile Assoc w R
p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.31_33delCTAinsTG Assoc w R
kanamycin
cycloserine
ethionamide ethA p.Ala381Pro Uncertain significance Mutation from literature
clofazimine pepQ c.715_717delTTGinsCC Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.205_207delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.796_798delATCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.991_993delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1603_1605delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2053_2055delCTGinsTA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1243_1245delCCAinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.715_717delTTGinsCC Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490987 c.205_207delCTGinsGA frameshift_variant&missense_variant 0.35 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.38 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491578 c.796_798delATCinsCG frameshift_variant&missense_variant 0.48 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.84 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303921 c.991_993delATCinsGT frameshift_variant&missense_variant 0.59 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 0.52 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304533 c.1603_1605delTTGinsCA frameshift_variant&missense_variant 0.55 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304983 c.2053_2055delCTGinsTA frameshift_variant&stop_gained 0.84 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance Mutation from literature
tlyA 1917970 c.31_33delCTAinsTG frameshift_variant&stop_gained 0.42 capreomycin Assoc w R
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R High-level resistance
katG 2155659 c.451_453delGTCinsCG frameshift_variant&missense_variant 0.52 isoniazid Assoc w R High-level resistance
pepQ 2859702 c.715_717delTTGinsCC frameshift_variant&missense_variant 0.43 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
fbiB 3642777 c.1243_1245delCCAinsGC frameshift_variant&missense_variant 0.76 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247431 p.Met306Ile missense_variant 0.3 ethambutol Assoc w R
embB 4247448 p.His312Arg missense_variant 0.7 ethambutol Mutation from literature
ethA 4326333 p.Ala381Pro missense_variant 1.0 ethionamide Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 525 c.525T>C synonymous_variant 0.38 isoniazid
dnaA 528 c.528G>T synonymous_variant 0.38 isoniazid
dnaA 531 c.531C>T synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 534 c.534T>C synonymous_variant 0.4 isoniazid Not assoc w R - Interim
dnaA 558 c.558G>C synonymous_variant 0.58 isoniazid
dnaA 561 c.561C>T synonymous_variant 0.62 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.6 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 0.6 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.6 isoniazid
dnaA 597 c.597C>G synonymous_variant 0.58 isoniazid Not assoc w R - Interim
dnaA 609 c.609C>G synonymous_variant 0.43 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.42 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.53 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.58 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>T synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 0.53 isoniazid
dnaA 762 c.762C>T synonymous_variant 0.55 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.58 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 798 c.798C>T synonymous_variant 0.56 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.57 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.53 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.47 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.43 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.42 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.42 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.45 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.5 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.55 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.56 isoniazid Not assoc w R - Interim
dnaA 877 c.877T>C synonymous_variant 0.61 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.57 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.56 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.52 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.48 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.48 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.48 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.47 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.45 isoniazid
dnaA 931 c.931_933delCTCinsTG frameshift_variant&missense_variant 0.47 isoniazid Uncertain significance
dnaA 945 c.945G>A synonymous_variant 0.41 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 0.56 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.62 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.76 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.58 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 0.61 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.48 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.52 isoniazid
dnaA 1110 c.1110T>A synonymous_variant 0.52 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.52 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 0.47 isoniazid
dnaA 1134 c.1134G>T synonymous_variant 0.5 isoniazid
dnaA 1137 c.1137C>T synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1140 c.1140C>G synonymous_variant 0.44 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.36 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 0.35 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.37 isoniazid Not assoc w R - Interim
dnaA 1173 c.1173C>T synonymous_variant 0.41 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.44 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.61 isoniazid Not assoc w R - Interim
dnaA 1203 c.1203T>C synonymous_variant 0.61 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.61 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.62 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.62 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.68 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>G synonymous_variant 0.76 isoniazid
dnaA 1275 c.1275C>T synonymous_variant 0.71 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.71 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.69 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.62 isoniazid
dnaA 1296 c.1296C>G synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 1299 c.1299G>C synonymous_variant 0.61 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>T synonymous_variant 0.61 isoniazid Not assoc w R - Interim
dnaA 1314 c.1314A>G synonymous_variant 0.58 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.56 isoniazid
dnaA 1329 c.1329A>G synonymous_variant 0.48 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.44 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 0.42 isoniazid
dnaA 1371 c.1371T>C synonymous_variant 0.47 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 0.51 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.55 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.6 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.6 isoniazid
dnaA 1395 c.1395G>A synonymous_variant 0.6 isoniazid
dnaA 1401 c.1401C>T synonymous_variant 0.6 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.67 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.7 isoniazid
dnaA 1425 c.1425C>T synonymous_variant 0.77 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.76 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.76 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.78 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.76 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.68 isoniazid
dnaA 1485 c.1485A>G synonymous_variant 0.57 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.59 isoniazid
gyrB 5788 c.549G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 5791 p.Glu184Asp missense_variant 0.38 levofloxacin
moxifloxacin
gyrB 5803 c.564A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 5812 c.573C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 5819 c.580C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5824 c.585A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 5827 c.588G>A synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrB 5848 c.609G>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 5849 c.610C>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 5863 c.624G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.3 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6100 c.861G>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.52 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6187 c.948C>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.72 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.43 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.43 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>T upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6316 c.-986G>A upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>T upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrB 6440 c.1201_1203delACCinsGG frameshift_variant&missense_variant 0.54 levofloxacin Uncertain significance
moxifloxacin
gyrA 6448 c.-854G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6451 c.-851A>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6457 c.-845T>G upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6475 c.-827C>G upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6484 c.-818A>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6490 c.-812T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrA 6502 c.-800T>A upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrB 6542 p.Ile435Leu missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6559 c.-743C>A upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6565 c.-737G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6688 c.-614C>A upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>T synonymous_variant 0.5 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6727 c.-575G>T upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.52 levofloxacin Uncertain significance
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6784 c.-518C>T upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6794 p.Ile519Leu missense_variant 0.64 levofloxacin
moxifloxacin
gyrB 6797 p.Gly520Thr missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 6838 c.-464C>A upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6889 c.-413G>A upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 6940 c.-362G>A upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6966 p.Ser576Thr missense_variant 0.77 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6970 p.Asp577Glu missense_variant 0.77 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>G upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 7057 c.-245C>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7204 c.-98C>T upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 7237 c.-65C>T upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7301 c.-1G>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 7307 c.6A>T synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 7324 c.23_24insAGG disruptive_inframe_insertion 0.29 levofloxacin
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 7343 c.42G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7347 c.46_48delGAAinsCG frameshift_variant&missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 7490 c.189C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7493 c.192C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7523 c.222C>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7601 c.300C>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7701 c.400C>T synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7778 c.477G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7811 c.510C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7832 c.531G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8051 c.750C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8096 c.795T>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8117 c.816C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8129 c.828T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8141 c.840C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8156 c.855T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8204 c.903C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.7 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 p.Asp415Glu missense_variant 0.62 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8570 p.Glu423Asp missense_variant 0.77 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8579 p.Asp426Glu missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8628 c.1327C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.72 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8767 p.Arg489Lys missense_variant 0.57 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8769 p.His490Tyr missense_variant 0.61 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8818 p.Ser506Asn missense_variant 0.78 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8894 c.1593C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8906 c.1605C>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8918 c.1617C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8951 c.1650G>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.59 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.65 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9065 c.1764C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9066 c.1765C>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.61 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>A synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9179 c.1878C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9185 c.1884C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9208 p.Lys636Arg missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 9281 c.1980C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9335 c.2034G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.61 levofloxacin
moxifloxacin
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.33 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.45 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.47 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.63 isoniazid
fgd1 490781 c.-2T>A upstream_gene_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.78 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 490860 c.78C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 490981 c.199C>A synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 490986 c.204G>A synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491491 p.Pro237Thr missense_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491502 p.Glu240Asp missense_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491503 p.Leu241Lys missense_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491560 p.His260Thr missense_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491568 c.786C>T synonymous_variant 0.4 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491569 p.Asp263His missense_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491625 c.843C>G synonymous_variant 0.51 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491646 c.864G>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
mshA 575521 c.174A>C synonymous_variant 0.45 ethionamide
isoniazid
mshA 575527 c.180G>C synonymous_variant 0.47 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.45 ethionamide
isoniazid
mshA 575542 c.195C>G synonymous_variant 0.5 ethionamide
isoniazid
mshA 575560 c.213C>T synonymous_variant 0.42 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.42 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.48 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.45 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.42 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575587 c.240C>G synonymous_variant 0.45 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 0.43 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.45 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.46 ethionamide
isoniazid
mshA 575668 c.321G>A synonymous_variant 0.42 ethionamide
isoniazid
mshA 575671 c.324G>C synonymous_variant 0.46 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.48 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.68 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.68 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 0.63 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.64 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.65 ethionamide
isoniazid
mshA 575770 c.423G>A synonymous_variant 0.61 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.61 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.54 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.52 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.55 ethionamide
isoniazid
mshA 575816 c.469C>T synonymous_variant 0.55 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.45 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.43 ethionamide
isoniazid
mshA 575833 c.486C>T synonymous_variant 0.48 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575837 c.490C>T synonymous_variant 0.48 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575845 c.498C>G synonymous_variant 0.48 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.52 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.58 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 0.59 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.35 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 0.35 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.38 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.44 ethionamide
isoniazid
mshA 576004 c.657T>C synonymous_variant 0.38 ethionamide
isoniazid
ccsA 619570 c.-321G>C upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>T upstream_gene_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 619594 c.-297G>C upstream_gene_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 619618 c.-273C>G upstream_gene_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>G upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619633 c.-258G>A upstream_gene_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.84 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>G upstream_gene_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 619900 p.Leu4Met missense_variant 0.53 capreomycin
amikacin Uncertain significance
kanamycin Uncertain significance
ccsA 619912 p.Val8Ile missense_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 619916 p.Gly9Glu missense_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 619923 c.33C>A synonymous_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 619947 c.57C>G synonymous_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 619953 c.63C>G synonymous_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 619962 c.72G>C synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 619968 c.78G>C synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 619969 p.Val27Ile missense_variant 0.73 capreomycin Not assoc w R - Interim
amikacin Not assoc w R
kanamycin Uncertain significance
ccsA 619981 c.91C>T synonymous_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 619989 c.99G>C synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 620208 c.318G>C synonymous_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 620226 c.336G>A synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620370 c.480C>G synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.81 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.71 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
Rv0565c 656256 c.1215G>C synonymous_variant 0.45 ethionamide
Rv0565c 656259 c.1212G>C synonymous_variant 0.48 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.5 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.5 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.55 ethionamide
Rv0565c 656295 c.1176C>T synonymous_variant 0.55 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.55 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.55 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.56 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 0.65 ethionamide
Rv0565c 656349 c.1122G>A synonymous_variant 0.59 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.6 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 0.52 ethionamide
Rv0565c 656367 c.1101_1104delTCGGinsGC frameshift_variant&synonymous_variant 0.53 ethionamide Uncertain significance
Rv0565c 656371 p.Pro367His missense_variant 0.53 ethionamide
Rv0565c 656375 c.1095_1096insAA frameshift_variant 0.57 ethionamide Uncertain significance
Rv0565c 656383 p.Val363Thr missense_variant 0.65 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.62 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.52 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.48 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.39 ethionamide
Rv0565c 656424 c.1047G>A synonymous_variant 0.38 ethionamide
Rv0565c 656427 c.1044G>A synonymous_variant 0.36 ethionamide
Rv0565c 656430 c.1041C>G synonymous_variant 0.35 ethionamide
Rv0565c 656439 c.1032C>G synonymous_variant 0.42 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 0.4 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.4 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.4 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.44 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.3 ethionamide Not assoc w R - Interim
Rv0565c 656515 p.Asp319Gly missense_variant 0.3 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 0.24 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 0.27 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.27 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 0.27 ethionamide
Rv0565c 656952 c.519A>C synonymous_variant 0.27 ethionamide Not assoc w R - Interim
Rv0565c 656964 c.507C>G synonymous_variant 0.27 ethionamide
Rv0565c 656967 c.504T>C synonymous_variant 0.27 ethionamide
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 0.9 ethionamide Uncertain significance
Rv0565c 657219 p.Ala84Val missense_variant 0.44 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.54 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.59 ethionamide
Rv0565c 657242 p.Glu77Lys missense_variant 0.6 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.69 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.72 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.69 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.69 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.73 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.56 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.68 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.7 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 0.8 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.77 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.75 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.75 ethionamide
Rv0565c 657700 c.-230A>G upstream_gene_variant 0.81 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.81 ethionamide
Rv0565c 657725 c.-255G>A upstream_gene_variant 0.79 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.69 ethionamide
hadA 731729 c.-201C>T upstream_gene_variant 0.5 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.56 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.69 isoniazid
hadA 731748 c.-182T>C upstream_gene_variant 0.69 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.8 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.8 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.75 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.72 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.52 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.47 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.42 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.38 isoniazid
hadA 732238 c.309G>T synonymous_variant 0.5 isoniazid
hadA 732250 c.321C>T synonymous_variant 0.66 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.71 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.75 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.76 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.79 isoniazid
hadA 732304 c.375C>T synonymous_variant 0.8 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.8 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.81 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.81 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.8 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.84 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.8 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.78 isoniazid
hadA 732388 c.459T>C synonymous_variant 0.72 isoniazid
hadA 732389 p.Ser154Ala missense_variant 0.72 isoniazid
hadA 732392 p.Asp155Asn missense_variant 0.72 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.72 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.75 isoniazid
hadA 732401 p.Ala158Pro missense_variant 0.75 isoniazid
nusG 734078 c.-176C>A upstream_gene_variant 0.46 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 0.49 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.48 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.48 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.49 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.48 rifampicin Uncertain significance
nusG 734123 c.-131C>T upstream_gene_variant 0.49 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 0.48 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.49 rifampicin
nusG 734135 c.-119G>T upstream_gene_variant 0.48 rifampicin
nusG 734144 c.-110G>T upstream_gene_variant 0.47 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.51 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.53 rifampicin
nusG 734362 p.Ala37Thr missense_variant 0.61 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.68 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.71 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.77 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.78 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.84 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.84 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>C synonymous_variant 0.79 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.79 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734538 c.285C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.8 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.77 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.79 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.77 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.69 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.71 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.64 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.58 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.47 rifampicin
nusG 734658 c.405A>G synonymous_variant 0.5 rifampicin Not assoc w R
nusG 734661 c.408A>C synonymous_variant 0.47 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.47 rifampicin
nusG 734667 c.414C>T synonymous_variant 0.5 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.54 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsAG frameshift_variant&missense_variant 0.54 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.8 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.79 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.78 rifampicin
nusG 734742 c.489T>C synonymous_variant 0.86 rifampicin
nusG 734750 p.Ser166Thr missense_variant 0.88 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.85 rifampicin
nusG 734771 p.Ala173Val missense_variant 0.84 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.77 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.76 rifampicin
nusG 734787 c.534T>C synonymous_variant 0.76 rifampicin
nusG 734791 p.Val180Thr missense_variant 0.73 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.75 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.74 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.72 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>A synonymous_variant 0.74 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.69 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.69 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.71 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.69 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.64 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.53 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.4 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.43 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.81 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.81 rifampicin
rpoB 760088 c.282C>G synonymous_variant 0.81 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.86 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.86 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.84 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.82 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 0.89 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.89 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.87 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 0.87 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.82 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.81 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.79 rifampicin
rpoB 760383 c.577C>T synonymous_variant 0.77 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.77 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.85 rifampicin
rpoB 760519 p.Thr238Ser missense_variant 0.85 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.84 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.81 rifampicin
rpoB 760547 c.741G>T synonymous_variant 0.84 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.81 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.88 rifampicin
rpoB 760607 c.801G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.8 rifampicin
rpoB 760679 c.873A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.7 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.68 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 0.69 rifampicin
rpoB 760760 c.954C>G synonymous_variant 0.7 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.76 rifampicin
rpoB 760784 c.978G>C synonymous_variant 0.77 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.74 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.77 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.76 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.78 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.79 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 0.8 rifampicin
rpoB 760877 c.1071G>A synonymous_variant 0.81 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.77 rifampicin
rpoB 760892 c.1086C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>G synonymous_variant 0.81 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.8 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.78 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.78 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 0.74 rifampicin
rpoB 760973 c.1167G>C synonymous_variant 0.76 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.88 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.83 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.82 rifampicin
rpoB 761126 c.1320G>A synonymous_variant 0.83 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.83 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.93 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.94 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761286 c.1480C>T synonymous_variant 0.94 rifampicin
rpoB 761289 p.Ser495Ala missense_variant 0.94 rifampicin
rpoB 761292 p.Val496Thr missense_variant 0.85 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.78 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.79 rifampicin
rpoB 761358 c.1552_1554delGTTinsAC frameshift_variant&missense_variant 0.79 rifampicin
rpoB 761373 p.Val523His missense_variant 0.77 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.5 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.63 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.77 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.84 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.83 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.85 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.86 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.9 rifampicin
rpoB 761651 c.1845C>T synonymous_variant 0.9 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761660 c.1854G>C synonymous_variant 0.88 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.88 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.91 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 0.9 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.84 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.88 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.88 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.88 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.79 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.76 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.68 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.59 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.59 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.58 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.58 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.58 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.65 rifampicin
rpoB 761867 c.2061C>G synonymous_variant 0.7 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 0.69 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.69 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.82 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.86 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.9 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.9 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.9 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.88 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.87 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 0.86 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.85 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.83 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.83 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.85 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.9 rifampicin
rpoB 762284 c.2478G>T synonymous_variant 0.88 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.74 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.74 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.72 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.7 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.74 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.72 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.74 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.77 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.83 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.82 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.8 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.84 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.83 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.85 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.81 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.78 rifampicin
rpoC 762545 c.-825C>G upstream_gene_variant 0.72 rifampicin
rpoC 762575 c.-795C>T upstream_gene_variant 0.59 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.44 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.44 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.5 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 0.62 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.69 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.69 rifampicin Uncertain significance
rpoB 762795 p.Asp997Asn missense_variant 0.7 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 0.72 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.77 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762894 c.3088C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 762917 c.-453C>T upstream_gene_variant 0.82 rifampicin
rpoC 762947 c.-423C>G upstream_gene_variant 0.82 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.87 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763049 c.-321G>A upstream_gene_variant 0.8 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.68 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.68 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.71 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763181 c.-189G>C upstream_gene_variant 0.73 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.68 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.68 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.69 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.7 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.72 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.62 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.32 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.39 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.75 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.83 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.86 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.85 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.84 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 0.78 rifampicin
rpoC 763672 c.303C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>T synonymous_variant 0.8 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.81 rifampicin
rpoC 763714 c.345G>T synonymous_variant 0.82 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.81 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.84 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.83 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.83 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.85 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.88 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.86 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.81 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763835 p.Ala156Leu missense_variant 0.71 rifampicin
rpoC 763853 c.484_486delGTCinsAT frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.73 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.67 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.67 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.67 rifampicin
rpoC 763885 c.516C>A synonymous_variant 0.71 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.71 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.72 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.71 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.74 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.82 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.81 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.83 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.78 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.67 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.7 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.74 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.79 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.81 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.79 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.78 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.85 rifampicin
rpoC 764182 c.813C>T synonymous_variant 0.79 rifampicin
rpoC 764198 c.829C>T synonymous_variant 0.78 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.79 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764213 p.Arg282Lys missense_variant 0.8 rifampicin Uncertain significance
rpoC 764257 c.888G>C synonymous_variant 0.74 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.69 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.68 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.71 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764329 c.960C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764359 c.990C>G synonymous_variant 0.63 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.67 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.68 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.75 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.86 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.88 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.83 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.83 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.84 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.81 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.75 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.8 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764734 c.1365C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.86 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764915 c.1546C>T synonymous_variant 0.86 rifampicin
rpoC 764932 c.1563C>G synonymous_variant 0.85 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.86 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.76 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765278 c.1909C>T synonymous_variant 0.53 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.56 rifampicin
rpoC 765317 c.1948_1950delCTAinsTG frameshift_variant&stop_gained 0.46 rifampicin
rpoC 765326 p.His653Ala missense_variant 0.46 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.5 rifampicin Uncertain significance
rpoC 765346 c.1977C>T synonymous_variant 0.69 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765370 c.2001G>T synonymous_variant 0.78 rifampicin
rpoC 765371 c.2002C>T synonymous_variant 0.78 rifampicin
rpoC 765379 c.2010G>A synonymous_variant 0.81 rifampicin
rpoC 765383 c.2014_2016delATGinsCT frameshift_variant&missense_variant 0.81 rifampicin
rpoC 765395 c.2026C>T synonymous_variant 0.84 rifampicin
rpoC 765404 c.2035_2037delCTGinsGC frameshift_variant&missense_variant 0.79 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.78 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.79 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765466 c.2097C>T synonymous_variant 0.84 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.93 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.89 rifampicin
rpoC 765550 c.2181C>T synonymous_variant 0.86 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.85 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.85 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.85 rifampicin
rpoC 765583 c.2214G>C synonymous_variant 0.86 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.83 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.81 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.87 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.87 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.89 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.85 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.81 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.82 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.8 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.81 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 0.85 rifampicin
rpoC 765928 c.2559C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.77 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.82 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.81 rifampicin
rpoC 766061 p.Val898Leu missense_variant 0.81 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.84 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.86 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.86 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 0.85 rifampicin
rpoC 766147 c.2778C>T synonymous_variant 0.79 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.79 rifampicin Uncertain significance
rpoC 766153 c.2784C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766178 p.Ile937Val missense_variant 0.59 rifampicin
rpoC 766247 p.Val960Ile missense_variant 0.5 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 0.68 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.67 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.67 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.67 rifampicin
rpoC 766280 c.2911_2913delAGCinsGA frameshift_variant&missense_variant 0.67 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 0.71 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 0.75 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.83 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.84 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.86 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.89 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.87 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.9 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.89 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.87 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 0.91 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.9 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.87 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.87 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766501 c.3132G>C synonymous_variant 0.85 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.74 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.73 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.79 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.79 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.78 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.78 rifampicin
rpoC 766588 c.3219G>A synonymous_variant 0.77 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.77 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.79 rifampicin
rpoC 766597 c.3228C>T synonymous_variant 0.79 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.85 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.92 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.85 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.86 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.89 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.88 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 0.87 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.86 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.86 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.85 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.86 rifampicin
rpoC 766777 c.3408C>G synonymous_variant 0.86 rifampicin
rpoC 766781 p.Val1138Thr missense_variant 0.85 rifampicin
rpoC 766801 c.3432C>A synonymous_variant 0.89 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>G synonymous_variant 0.73 rifampicin
rpoC 766861 c.3492G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.73 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.7 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.7 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.72 rifampicin
rpoC 766915 c.3546C>T synonymous_variant 0.61 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.59 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.52 rifampicin
rpoC 766934 p.Glu1189Ser missense_variant 0.52 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>T synonymous_variant 0.72 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.88 rifampicin
rpoC 767059 c.3690T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767080 c.3711G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.81 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.79 rifampicin
rpoC 767152 c.3783T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767176 c.3807C>T synonymous_variant 0.86 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.86 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.71 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.65 rifampicin
rpoC 767270 p.Thr1301Ala missense_variant 0.67 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.62 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
mmpL5 775856 c.2625T>C synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Ser missense_variant 0.56 clofazimine
bedaquiline
mmpL5 775865 c.2616T>A synonymous_variant 0.56 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.63 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 775901 c.2580G>A synonymous_variant 0.58 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.65 clofazimine
bedaquiline
mmpL5 775913 c.2568C>G synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.51 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.39 clofazimine
bedaquiline
mmpL5 775973 c.2506_2508delTTGinsCC frameshift_variant&missense_variant 0.29 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775981 p.Leu834Met missense_variant 0.47 clofazimine
bedaquiline
rpsL 781128 c.-432C>G upstream_gene_variant 0.67 streptomycin
rpsL 781134 c.-426T>C upstream_gene_variant 0.67 streptomycin
rpsL 781138 c.-422_-421delCAinsGC upstream_gene_variant 0.67 streptomycin
rpsL 781143 c.-417T>C upstream_gene_variant 0.67 streptomycin
rpsL 781147 c.-413T>C upstream_gene_variant 0.63 streptomycin
rpsL 781153 c.-407G>T upstream_gene_variant 0.65 streptomycin
rpsL 781158 c.-402C>G upstream_gene_variant 0.68 streptomycin
rpsL 781164 c.-396T>C upstream_gene_variant 0.75 streptomycin
rpsL 781182 c.-378G>T upstream_gene_variant 0.82 streptomycin
rpsL 781197 c.-363A>G upstream_gene_variant 0.83 streptomycin
rpsL 781203 c.-357C>G upstream_gene_variant 0.79 streptomycin
rpsL 781209 c.-351C>G upstream_gene_variant 0.75 streptomycin
rpsL 781218 c.-342C>G upstream_gene_variant 0.79 streptomycin
rpsL 781224 c.-336T>C upstream_gene_variant 0.82 streptomycin
rpsL 781230 c.-330T>C upstream_gene_variant 0.82 streptomycin
rpsL 781234 c.-326G>C upstream_gene_variant 0.82 streptomycin
rpsL 781240 c.-320A>T upstream_gene_variant 0.85 streptomycin
rpsL 781266 c.-294G>C upstream_gene_variant 0.75 streptomycin
rpsL 781270 c.-290A>C upstream_gene_variant 0.64 streptomycin
rpsL 781571 c.12C>T synonymous_variant 0.68 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.85 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.85 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.85 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.88 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.89 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.93 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.91 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.89 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.85 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.84 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.86 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.87 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.87 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.87 streptomycin
rpsL 781805 c.246G>A synonymous_variant 0.89 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.88 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.87 streptomycin
rpsL 781817 c.258G>C synonymous_variant 0.86 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.88 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.88 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.86 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.84 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.84 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.85 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.81 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.8 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.81 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.74 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.7 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.84 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.84 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.83 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.85 linezolid
rplC 800594 c.-215C>T upstream_gene_variant 0.87 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.85 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.85 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.91 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.83 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.83 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.82 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.8 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.82 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.77 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.76 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.72 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 0.6 linezolid
rplC 800806 c.-3G>C upstream_gene_variant 0.58 linezolid
rplC 800807 c.-2C>T upstream_gene_variant 0.58 linezolid
rplC 800808 c.-1A>C upstream_gene_variant 0.58 linezolid Uncertain significance
rplC 800815 c.7C>A synonymous_variant 0.56 linezolid
rplC 800820 c.12G>A synonymous_variant 0.58 linezolid
rplC 800829 c.21C>G synonymous_variant 0.66 linezolid
rplC 800844 c.36T>C synonymous_variant 0.67 linezolid
rplC 800856 c.48A>G synonymous_variant 0.6 linezolid
rplC 800865 c.57A>G synonymous_variant 0.48 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.45 linezolid
rplC 800874 c.66A>G synonymous_variant 0.43 linezolid
rplC 800875 c.67_69delGTAinsAT frameshift_variant&missense_variant 0.43 linezolid
rplC 800880 c.72A>G synonymous_variant 0.58 linezolid
rplC 800889 c.81C>G synonymous_variant 0.68 linezolid
rplC 800892 c.84G>C synonymous_variant 0.68 linezolid
rplC 800904 c.96G>C synonymous_variant 0.79 linezolid
rplC 800907 c.99C>G synonymous_variant 0.79 linezolid
rplC 800916 c.108A>G synonymous_variant 0.73 linezolid
rplC 800922 c.114C>G synonymous_variant 0.63 linezolid
rplC 800928 c.120C>T synonymous_variant 0.61 linezolid
rplC 800931 c.123G>C synonymous_variant 0.61 linezolid
rplC 800937 c.129A>G synonymous_variant 0.65 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.61 linezolid
rplC 800946 c.138T>C synonymous_variant 0.69 linezolid
rplC 800949 c.141T>C synonymous_variant 0.72 linezolid
rplC 800970 c.162T>C synonymous_variant 0.79 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.75 linezolid
rplC 800985 c.177A>C synonymous_variant 0.75 linezolid
rplC 801004 p.Leu66Val missense_variant 0.56 linezolid
rplC 801009 c.201A>C synonymous_variant 0.5 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.56 linezolid
rplC 801027 c.219C>G synonymous_variant 0.56 linezolid
rplC 801033 c.225C>G synonymous_variant 0.53 linezolid
rplC 801039 c.231A>G synonymous_variant 0.5 linezolid
rplC 801132 c.324T>C synonymous_variant 0.5 linezolid
rplC 801136 p.Ser110Ala missense_variant 0.53 linezolid
rplC 801147 c.339T>C synonymous_variant 0.61 linezolid
rplC 801150 c.342G>C synonymous_variant 0.58 linezolid
rplC 801153 c.345G>C synonymous_variant 0.6 linezolid
rplC 801156 c.348T>C synonymous_variant 0.65 linezolid
rplC 801168 c.360C>A synonymous_variant 0.67 linezolid
rplC 801171 c.363A>G synonymous_variant 0.67 linezolid
rplC 801174 c.366T>C synonymous_variant 0.67 linezolid
rplC 801195 c.387G>C synonymous_variant 0.67 linezolid
rplC 801205 c.397_399delCGCinsAT frameshift_variant&missense_variant 0.71 linezolid
rplC 801222 c.414T>C synonymous_variant 0.7 linezolid
rplC 801246 c.438C>T synonymous_variant 0.58 linezolid
rplC 801249 c.441T>C synonymous_variant 0.58 linezolid
rplC 801255 c.447C>T synonymous_variant 0.59 linezolid
rplC 801258 c.450C>G synonymous_variant 0.57 linezolid
rplC 801279 c.471G>C synonymous_variant 0.56 linezolid
rplC 801282 c.474G>C synonymous_variant 0.65 linezolid
rplC 801307 c.499_501delGCCinsTG frameshift_variant&missense_variant 0.6 linezolid
rplC 801312 c.504G>C synonymous_variant 0.63 linezolid
rplC 801321 c.513C>T synonymous_variant 0.58 linezolid Not assoc w R - Interim
rplC 801323 p.Asn172Ser missense_variant 0.58 linezolid
rplC 801327 c.519C>T synonymous_variant 0.58 linezolid
rplC 801330 c.522G>C synonymous_variant 0.58 linezolid
rplC 801339 c.531T>C synonymous_variant 0.62 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.68 linezolid
rplC 801348 c.540T>G synonymous_variant 0.74 linezolid
rplC 801357 c.549T>C synonymous_variant 0.76 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.79 linezolid
rplC 801396 c.588T>C synonymous_variant 0.71 linezolid
rplC 801402 c.594T>C synonymous_variant 0.67 linezolid
rplC 801405 c.597T>C synonymous_variant 0.69 linezolid
rplC 801423 c.615G>C synonymous_variant 0.69 linezolid
rplC 801427 p.Met207Val missense_variant 0.69 linezolid
rplC 801438 c.630T>C synonymous_variant 0.56 linezolid
rplC 801442 p.Ile212Val missense_variant 0.54 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1303441 c.511T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303542 c.612C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303599 c.669C>T synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303647 c.717G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.81 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 0.72 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303905 c.975G>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1303965 c.1035G>A synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>A synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>T synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304046 c.1116C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304058 c.1128G>A synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304088 c.1158C>T synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304103 c.1173G>A synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304137 p.Ala403Ser missense_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304154 c.1224G>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304157 c.1227G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304162 p.Arg411Gln missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>T synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304226 c.1296C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304241 c.1311G>A synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304523 c.1593G>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304530 p.Ser534Thr missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304544 p.Asp538Glu missense_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>A synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.55 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304796 c.1866G>A synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304826 c.1896G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.75 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304880 c.1950C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1305014 p.Thr695Ser missense_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1305051 c.2121G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1305075 c.2145T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305114 c.2184T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.57 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305144 c.2214G>A synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1305199 p.Ala757Ser missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>T synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305219 c.2289T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 0.29 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1305348 c.2418C>T synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305361 c.2431C>T synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1305375 c.2445C>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305400 p.His824Tyr missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
atpE 1460816 c.-229T>C upstream_gene_variant 0.72 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.66 bedaquiline
atpE 1460832 c.-213C>T upstream_gene_variant 0.66 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.66 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.6 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.62 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.57 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.54 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.58 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.6 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.58 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.6 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 0.58 bedaquiline
atpE 1461194 c.150C>T synonymous_variant 0.54 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.53 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.46 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.39 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.3 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.26 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.8 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.8 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473752 n.95G>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473936 n.279A>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1473966 n.309T>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473981 n.324_325insT non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474036 n.379G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474110 n.453A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474969 n.1312G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475007 n.1350C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475009 n.1352G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475016 n.1359C>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475409 n.1752T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.82 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475652 n.1995C>T non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.75 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.81 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476717 n.3060C>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
inhA 1673499 c.-703T>C upstream_gene_variant 0.77 ethionamide
isoniazid Uncertain significance
inhA 1673505 c.-697A>C upstream_gene_variant 0.81 ethionamide
isoniazid
inhA 1673517 c.-685G>A upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673565 c.-637G>T upstream_gene_variant 0.86 ethionamide
isoniazid
fabG1 1673569 p.Val44Ile missense_variant 0.85 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.73 ethionamide
isoniazid Uncertain significance
fabG1 1673710 c.271_273delCTAinsGC frameshift_variant&missense_variant 0.69 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.69 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673730 c.-472C>T upstream_gene_variant 0.68 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1673733 p.Met98Ile missense_variant 0.68 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.65 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.65 ethionamide
isoniazid
fabG1 1673758 c.319_321delAAGinsCA frameshift_variant&missense_variant 0.63 ethionamide
isoniazid
fabG1 1673890 p.Ala151Ser missense_variant 0.56 ethionamide
isoniazid
inhA 1673901 c.-301A>C upstream_gene_variant 0.67 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.67 ethionamide
isoniazid
inhA 1673916 c.-286A>T upstream_gene_variant 0.65 ethionamide
isoniazid
fabG1 1673917 c.478_480delGTGinsCC frameshift_variant&missense_variant 0.65 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.69 ethionamide
isoniazid
inhA 1673934 c.-268C>T upstream_gene_variant 0.74 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.75 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.6 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 0.56 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 0.62 ethionamide
isoniazid
inhA 1674012 c.-190C>G upstream_gene_variant 0.65 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.7 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 0.7 ethionamide
isoniazid
fabG1 1674049 p.Gln204Glu missense_variant 0.73 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1674060 c.-142A>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.74 ethionamide
isoniazid
inhA 1674084 c.-118C>G upstream_gene_variant 0.72 ethionamide
isoniazid
inhA 1674117 c.-85C>G upstream_gene_variant 0.65 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 0.6 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 0.6 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.58 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.57 ethionamide
isoniazid
inhA 1674331 c.130C>T synonymous_variant 0.59 ethionamide
isoniazid
inhA 1674336 c.135G>C synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 0.58 ethionamide Uncertain significance
isoniazid
inhA 1674368 p.Ala56Glu missense_variant 0.54 ethionamide
isoniazid
inhA 1674375 c.174C>G synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674382 p.Leu61Ile missense_variant 0.56 ethionamide
isoniazid
inhA 1674462 c.261G>A synonymous_variant 0.36 ethionamide
isoniazid
inhA 1674471 c.270G>T synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.52 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.57 ethionamide
isoniazid
inhA 1674504 c.303C>G