Run ID: ERR4831546
Sample name:
Date: 2024-10-03T22:12:25.274647
Number of reads: 1044149
Percentage reads mapped: 30.35
Median coverage: 18.0
Strain: M.canetti;lineage2.2.2;lineage6.2
Spoligotype:
Drug-resistance: HR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage6.2 | West-Africa 2 | RD702 | 0.08 |
lineage2 | East-Asian | RD105 | 0.93 |
La1.2.BCG | M.bovis | None | 0.17 |
lineage2.2.2 | East-Asian (Beijing) | RD105;RD207 | 0.64 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 0.97 |
M.canetti | M.canetti | None | 0.08 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
ethambutol | embB | p.Met306Ile | Assoc w R | |
p.His312Arg | Mutation from literature | |||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ethA | p.Ala381Pro | Uncertain significance | Mutation from literature |
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.86 | streptomycin | Uncertain significance | Mutation from literature |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
embB | 4247431 | p.Met306Ile | missense_variant | 0.3 | ethambutol | Assoc w R | |
embB | 4247448 | p.His312Arg | missense_variant | 0.7 | ethambutol | Mutation from literature | |
ethA | 4326333 | p.Ala381Pro | missense_variant | 1.0 | ethionamide | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 525 | c.525T>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 528 | c.528G>T | synonymous_variant | 0.38 | isoniazid | |
dnaA | 531 | c.531C>T | synonymous_variant | 0.41 | isoniazid | Not assoc w R - Interim |
dnaA | 534 | c.534T>C | synonymous_variant | 0.4 | isoniazid | Not assoc w R - Interim |
dnaA | 558 | c.558G>C | synonymous_variant | 0.58 | isoniazid | |
dnaA | 561 | c.561C>T | synonymous_variant | 0.62 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 0.6 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 0.62 | isoniazid | Not assoc w R - Interim |
dnaA | 588 | c.588A>G | synonymous_variant | 0.6 | isoniazid | |
dnaA | 591 | c.591C>G | synonymous_variant | 0.6 | isoniazid | |
dnaA | 597 | c.597C>G | synonymous_variant | 0.58 | isoniazid | Not assoc w R - Interim |
dnaA | 609 | c.609C>G | synonymous_variant | 0.43 | isoniazid | |
dnaA | 610 | c.610C>T | synonymous_variant | 0.42 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.53 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.58 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>T | synonymous_variant | 0.54 | isoniazid | Not assoc w R - Interim |
dnaA | 756 | c.756T>C | synonymous_variant | 0.53 | isoniazid | |
dnaA | 762 | c.762C>T | synonymous_variant | 0.55 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.54 | isoniazid | Not assoc w R - Interim |
dnaA | 798 | c.798C>T | synonymous_variant | 0.56 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.57 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.53 | isoniazid | |
dnaA | 819 | c.819C>T | synonymous_variant | 0.47 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.43 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.45 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.5 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.55 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.56 | isoniazid | Not assoc w R - Interim |
dnaA | 877 | c.877T>C | synonymous_variant | 0.61 | isoniazid | |
dnaA | 882 | c.882C>T | synonymous_variant | 0.57 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.56 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.52 | isoniazid | |
dnaA | 909 | c.909A>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 912 | c.912T>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.47 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 0.45 | isoniazid | |
dnaA | 931 | c.931_933delCTCinsTTG | synonymous_variant | 0.47 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.41 | isoniazid | |
dnaA | 1038 | c.1038A>G | synonymous_variant | 0.56 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.62 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.76 | isoniazid | |
dnaA | 1077 | c.1077A>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 1080 | c.1080C>G | synonymous_variant | 0.61 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.5 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.52 | isoniazid | |
dnaA | 1110 | c.1110T>A | synonymous_variant | 0.52 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.52 | isoniazid | |
dnaA | 1119 | c.1119G>A | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1134 | c.1134G>T | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1137 | c.1137C>T | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
dnaA | 1140 | c.1140C>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1164 | c.1164A>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 1173 | c.1173C>T | synonymous_variant | 0.41 | isoniazid | |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1197 | c.1197T>C | synonymous_variant | 0.61 | isoniazid | Not assoc w R - Interim |
dnaA | 1203 | c.1203T>C | synonymous_variant | 0.61 | isoniazid | |
dnaA | 1215 | c.1215C>T | synonymous_variant | 0.61 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.62 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.62 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.7 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>G | synonymous_variant | 0.76 | isoniazid | |
dnaA | 1275 | c.1275C>T | synonymous_variant | 0.71 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.71 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.69 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 0.62 | isoniazid | |
dnaA | 1296 | c.1296C>G | synonymous_variant | 0.62 | isoniazid | Not assoc w R - Interim |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.61 | isoniazid | Not assoc w R - Interim |
dnaA | 1302 | c.1302C>T | synonymous_variant | 0.61 | isoniazid | Not assoc w R - Interim |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.56 | isoniazid | |
dnaA | 1329 | c.1329A>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1332 | c.1332A>C | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1341 | c.1341G>C | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1371 | c.1371T>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1374 | c.1374G>A | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.55 | isoniazid | |
dnaA | 1389 | c.1389C>G | synonymous_variant | 0.6 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.6 | isoniazid | |
dnaA | 1395 | c.1395G>A | synonymous_variant | 0.6 | isoniazid | |
dnaA | 1401 | c.1401C>T | synonymous_variant | 0.6 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.67 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.7 | isoniazid | |
dnaA | 1425 | c.1425C>T | synonymous_variant | 0.77 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.76 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 0.76 | isoniazid | |
dnaA | 1441 | c.1441C>T | synonymous_variant | 0.78 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 0.76 | isoniazid | |
dnaA | 1470 | c.1470C>T | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1485 | c.1485A>G | synonymous_variant | 0.57 | isoniazid | |
dnaA | 1488 | c.1488A>G | synonymous_variant | 0.59 | isoniazid | |
gyrB | 5788 | c.549G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5791 | p.Glu184Asp | missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5803 | c.564A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5812 | c.573C>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5819 | c.580C>T | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5848 | c.609G>T | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5849 | c.610C>T | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5863 | c.624G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5873 | c.634A>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6086 | p.Thr283Pro | missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6091 | c.852G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6100 | c.861G>T | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6103 | c.864G>A | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6123 | p.Ala295Gly | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6130 | c.891T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6184 | c.945C>T | synonymous_variant | 0.69 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6187 | c.948C>T | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6209 | c.970C>T | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6215 | p.Ser326Thr | missense_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6259 | p.Asp340Glu | missense_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6265 | c.1026C>T | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6304 | c.-998C>T | upstream_gene_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6316 | c.-986G>A | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.74 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6400 | c.-902C>T | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6418 | c.-884C>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6427 | c.-875T>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6430 | c.-872A>G | upstream_gene_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6440 | p.Thr401Ala | missense_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6448 | c.-854G>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6451 | c.-851A>G | upstream_gene_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6457 | c.-845T>G | upstream_gene_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6469 | c.-833T>G | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6475 | c.-827C>G | upstream_gene_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6484 | c.-818A>G | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6490 | c.-812T>C | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6496 | c.-806G>C | upstream_gene_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6499 | c.-803A>G | upstream_gene_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6502 | c.-800T>A | upstream_gene_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6523 | c.-779G>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6526 | c.-776T>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6542 | p.Ile435Leu | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6547 | c.-755T>C | upstream_gene_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6550 | c.1311A>G | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6551 | c.1312T>C | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6559 | c.-743C>A | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6565 | c.-737G>C | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6571 | c.-731T>C | upstream_gene_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6577 | c.1338T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6583 | c.-719G>C | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6586 | c.-716T>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6688 | c.-614C>A | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6715 | c.1476C>T | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6727 | c.-575G>T | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 0.65 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6763 | c.1524G>C | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6784 | c.-518C>T | upstream_gene_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6794 | p.Ile519Leu | missense_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6838 | c.-464C>A | upstream_gene_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6866 | c.-436C>T | upstream_gene_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6889 | c.-413G>A | upstream_gene_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6898 | c.-404G>C | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6940 | c.-362G>A | upstream_gene_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6966 | p.Ser576Thr | missense_variant | 0.77 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrB | 6970 | p.Asp577Glu | missense_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7021 | c.-281G>C | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7030 | c.-272C>G | upstream_gene_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7057 | c.-245C>G | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7060 | c.1821T>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7153 | c.1914G>C | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7177 | c.-125G>A | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7204 | c.-98C>T | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7213 | c.-89G>A | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7225 | c.-77T>C | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7237 | c.-65C>T | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7246 | c.2007T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7301 | c.-1G>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7307 | c.6A>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7324 | c.23_24insAGG | disruptive_inframe_insertion | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7334 | c.33G>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7335 | p.Leu12Val | missense_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7343 | c.42G>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7347 | p.Glu16Gln | missense_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7355 | c.54T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.69 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.68 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7406 | c.105G>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>T | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.79 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7490 | c.189C>T | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7493 | c.192C>T | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>G | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7565 | c.264C>T | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7587 | c.286C>T | synonymous_variant | 0.74 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7701 | c.400C>T | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409_411delTTGinsCTC | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7775 | c.474C>T | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7778 | c.477G>T | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>C | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.82 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7811 | c.510C>T | synonymous_variant | 0.82 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7832 | c.531G>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7868 | c.567C>T | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8051 | c.750C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8054 | c.753T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8057 | c.756A>G | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>A | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>G | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8117 | c.816C>T | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8126 | c.825G>C | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8135 | c.834C>G | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8141 | c.840C>T | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8204 | c.903C>T | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8210 | c.909G>A | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8222 | c.921C>T | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8228 | c.927G>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8235 | c.934_936delTTAinsCTG | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8246 | c.945C>G | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.52 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8339 | c.1038A>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.7 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.74 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8393 | c.1092T>C | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.76 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8405 | c.1104C>T | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8465 | c.1164C>G | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8472 | c.1171C>T | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | p.Asp415Glu | missense_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8552 | c.1251C>G | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.74 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8570 | p.Glu423Asp | missense_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8576 | c.1275C>A | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8579 | p.Asp426Glu | missense_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.82 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8609 | c.1308G>C | synonymous_variant | 0.81 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.76 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8628 | c.1327C>T | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8655 | p.Ile452Val | missense_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.57 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8769 | p.His490Tyr | missense_variant | 0.61 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8783 | c.1482G>T | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>T | synonymous_variant | 0.73 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.78 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.77 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.74 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.73 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8882 | c.1581G>A | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8894 | c.1593C>T | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8906 | c.1605C>A | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8918 | c.1617C>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8945 | c.1644G>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645T>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8951 | c.1650G>A | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.59 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>G | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9026 | c.1725G>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9029 | c.1728T>G | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.65 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9065 | c.1764C>G | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9066 | c.1765C>A | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9128 | c.1827C>G | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9147 | p.Gly616Ser | missense_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9164 | c.1863G>A | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9179 | c.1878C>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9185 | c.1884C>T | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9197 | c.1896G>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9208 | p.Lys636Arg | missense_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9248 | c.1947G>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9251 | c.1950G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9281 | c.1980C>G | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9287 | c.1986G>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.69 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.79 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>G | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13876 | c.-318G>C | upstream_gene_variant | 0.33 | isoniazid | |
Rv0010c | 13890 | c.-332T>C | upstream_gene_variant | 0.45 | isoniazid | |
Rv0010c | 13893 | c.-335T>G | upstream_gene_variant | 0.47 | isoniazid | |
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.63 | isoniazid | |
fgd1 | 490781 | c.-2T>A | upstream_gene_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.78 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.72 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490818 | c.36C>T | synonymous_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490851 | c.69A>C | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490854 | c.72C>T | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490860 | c.78C>T | synonymous_variant | 0.69 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.68 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490902 | c.120T>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490962 | c.180T>C | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490971 | c.189A>G | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490981 | c.199C>A | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490986 | c.204G>A | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490987 | p.Leu69Val | missense_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491491 | p.Pro237Thr | missense_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491502 | p.Glu240Asp | missense_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491503 | p.Leu241Lys | missense_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491508 | c.726A>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491512 | p.Asn244Glu | missense_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491547 | c.765A>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491560 | p.His260Thr | missense_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491568 | c.786C>T | synonymous_variant | 0.4 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491569 | p.Asp263His | missense_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491578 | p.Ile266Leu | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491603 | p.Ala274Glu | missense_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491610 | c.828A>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491625 | c.843C>G | synonymous_variant | 0.51 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491658 | c.876A>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491661 | c.879C>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491673 | c.891A>C | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 575521 | c.174A>C | synonymous_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575527 | c.180G>C | synonymous_variant | 0.47 | isoniazid | |
ethionamide | ||||||
mshA | 575536 | c.189T>C | synonymous_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575542 | c.195C>G | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
mshA | 575560 | c.213C>T | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575561 | p.Met72Val | missense_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575569 | c.222A>G | synonymous_variant | 0.48 | isoniazid | |
ethionamide | ||||||
mshA | 575571 | p.Ser75Thr | missense_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575576 | c.229C>T | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575587 | c.240C>G | synonymous_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575590 | c.243T>G | synonymous_variant | 0.43 | isoniazid | |
ethionamide | ||||||
mshA | 575593 | c.246G>C | synonymous_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575668 | c.321G>A | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575671 | c.324G>C | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575674 | c.327G>C | synonymous_variant | 0.48 | isoniazid | |
ethionamide | ||||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.68 | isoniazid | |
ethionamide | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.68 | isoniazid | |
ethionamide | ||||||
mshA | 575752 | c.405G>C | synonymous_variant | 0.63 | isoniazid | |
ethionamide | ||||||
mshA | 575756 | c.409C>T | synonymous_variant | 0.64 | isoniazid | |
ethionamide | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.65 | isoniazid | |
ethionamide | ||||||
mshA | 575770 | c.423G>A | synonymous_variant | 0.61 | isoniazid | |
ethionamide | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.61 | isoniazid | |
ethionamide | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.54 | isoniazid | |
ethionamide | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 0.52 | isoniazid | |
ethionamide | ||||||
mshA | 575785 | c.438T>C | synonymous_variant | 0.55 | isoniazid | |
ethionamide | ||||||
mshA | 575816 | c.469C>T | synonymous_variant | 0.55 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.43 | isoniazid | |
ethionamide | ||||||
mshA | 575833 | c.486C>T | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575837 | c.490C>T | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575845 | c.498C>G | synonymous_variant | 0.48 | isoniazid | |
ethionamide | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.52 | isoniazid | |
ethionamide | ||||||
mshA | 575878 | c.531A>G | synonymous_variant | 0.58 | isoniazid | |
ethionamide | ||||||
mshA | 575887 | c.540G>C | synonymous_variant | 0.59 | isoniazid | |
ethionamide | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.35 | isoniazid | |
ethionamide | ||||||
mshA | 575953 | c.606G>C | synonymous_variant | 0.35 | isoniazid | |
ethionamide | ||||||
mshA | 575980 | c.633T>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
mshA | 575984 | c.637T>C | synonymous_variant | 0.44 | isoniazid | |
ethionamide | ||||||
mshA | 576004 | c.657T>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.72 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.74 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619579 | c.-312G>T | upstream_gene_variant | 0.74 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.81 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619594 | c.-297G>C | upstream_gene_variant | 0.86 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619618 | c.-273C>G | upstream_gene_variant | 0.84 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619627 | c.-264C>G | upstream_gene_variant | 0.83 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619633 | c.-258G>A | upstream_gene_variant | 0.84 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.84 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619668 | c.-223_-222delCGinsGC | upstream_gene_variant | 0.74 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619672 | c.-219A>T | upstream_gene_variant | 0.75 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619676 | c.-215C>G | upstream_gene_variant | 0.77 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619900 | p.Leu4Met | missense_variant | 0.53 | kanamycin | Uncertain significance |
capreomycin | ||||||
amikacin | Uncertain significance | |||||
ccsA | 619912 | p.Val8Ile | missense_variant | 0.61 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619916 | p.Gly9Glu | missense_variant | 0.61 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619923 | c.33C>A | synonymous_variant | 0.65 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619947 | c.57C>G | synonymous_variant | 0.65 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619953 | c.63C>G | synonymous_variant | 0.69 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619962 | c.72G>C | synonymous_variant | 0.73 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619968 | c.78G>C | synonymous_variant | 0.73 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619969 | p.Val27Ile | missense_variant | 0.73 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R | |||||
ccsA | 619981 | c.91C>T | synonymous_variant | 0.64 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619989 | c.99G>C | synonymous_variant | 0.62 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620198 | p.Gln103Leu | missense_variant | 0.65 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620208 | c.318G>C | synonymous_variant | 0.56 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620226 | c.336G>A | synonymous_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620245 | c.355T>C | synonymous_variant | 0.43 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 0.79 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620317 | p.Val143Leu | missense_variant | 0.82 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.89 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620349 | c.459A>G | synonymous_variant | 0.89 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.9 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.9 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620370 | c.480C>G | synonymous_variant | 0.9 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.9 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.92 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.92 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.86 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.81 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.71 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv0565c | 656256 | c.1215G>C | synonymous_variant | 0.45 | ethionamide | |
Rv0565c | 656259 | c.1212G>C | synonymous_variant | 0.48 | ethionamide | |
Rv0565c | 656265 | c.1206G>C | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 656268 | p.Met401Ile | missense_variant | 0.5 | ethionamide | |
Rv0565c | 656289 | c.1182C>G | synonymous_variant | 0.55 | ethionamide | |
Rv0565c | 656295 | c.1176C>T | synonymous_variant | 0.55 | ethionamide | |
Rv0565c | 656298 | c.1173G>C | synonymous_variant | 0.55 | ethionamide | |
Rv0565c | 656304 | c.1167T>C | synonymous_variant | 0.55 | ethionamide | |
Rv0565c | 656310 | c.1161T>C | synonymous_variant | 0.56 | ethionamide | |
Rv0565c | 656325 | c.1146C>G | synonymous_variant | 0.65 | ethionamide | |
Rv0565c | 656349 | c.1122G>A | synonymous_variant | 0.59 | ethionamide | |
Rv0565c | 656358 | c.1113T>C | synonymous_variant | 0.6 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656364 | c.1107T>C | synonymous_variant | 0.52 | ethionamide | |
Rv0565c | 656367 | c.1101_1104delTCGGinsGC | frameshift_variant&synonymous_variant | 0.53 | ethionamide | Uncertain significance |
Rv0565c | 656371 | p.Pro367His | missense_variant | 0.53 | ethionamide | |
Rv0565c | 656375 | c.1095_1096insAA | frameshift_variant | 0.57 | ethionamide | Uncertain significance |
Rv0565c | 656383 | p.Val363Thr | missense_variant | 0.65 | ethionamide | |
Rv0565c | 656391 | c.1080C>G | synonymous_variant | 0.62 | ethionamide | |
Rv0565c | 656412 | c.1059T>G | synonymous_variant | 0.52 | ethionamide | |
Rv0565c | 656418 | c.1053A>G | synonymous_variant | 0.48 | ethionamide | |
Rv0565c | 656423 | c.1048T>C | synonymous_variant | 0.39 | ethionamide | |
Rv0565c | 656424 | c.1047G>A | synonymous_variant | 0.38 | ethionamide | |
Rv0565c | 656427 | c.1044G>A | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 656430 | c.1041C>G | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656439 | c.1032C>G | synonymous_variant | 0.42 | ethionamide | |
Rv0565c | 656448 | c.1023T>C | synonymous_variant | 0.4 | ethionamide | |
Rv0565c | 656454 | c.1017G>C | synonymous_variant | 0.4 | ethionamide | |
Rv0565c | 656457 | c.1014T>C | synonymous_variant | 0.4 | ethionamide | |
Rv0565c | 656469 | c.1002T>C | synonymous_variant | 0.44 | ethionamide | |
Rv0565c | 656511 | c.960T>C | synonymous_variant | 0.3 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656515 | p.Asp319Gly | missense_variant | 0.3 | ethionamide | |
Rv0565c | 656582 | p.Leu297Met | missense_variant | 0.24 | ethionamide | |
Rv0565c | 656589 | c.882T>C | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 656946 | c.525T>C | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 656949 | c.522G>A | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 656952 | c.519A>C | synonymous_variant | 0.27 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656964 | c.507C>G | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 656967 | c.504T>C | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 0.9 | ethionamide | Uncertain significance |
Rv0565c | 657219 | p.Ala84Val | missense_variant | 0.44 | ethionamide | |
Rv0565c | 657233 | p.Ile80Val | missense_variant | 0.54 | ethionamide | |
Rv0565c | 657237 | c.234A>G | synonymous_variant | 0.59 | ethionamide | |
Rv0565c | 657242 | p.Glu77Lys | missense_variant | 0.6 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.69 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.72 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.69 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.69 | ethionamide | |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.73 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.56 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.68 | ethionamide | |
Rv0565c | 657650 | c.-180G>A | upstream_gene_variant | 0.7 | ethionamide | |
Rv0565c | 657659 | c.-189G>A | upstream_gene_variant | 0.8 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.77 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.75 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.75 | ethionamide | |
Rv0565c | 657700 | c.-230A>G | upstream_gene_variant | 0.81 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.81 | ethionamide | |
Rv0565c | 657725 | c.-255G>A | upstream_gene_variant | 0.79 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.69 | ethionamide | |
hadA | 731729 | c.-201C>T | upstream_gene_variant | 0.5 | isoniazid | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.56 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.69 | isoniazid | |
hadA | 731748 | c.-182T>C | upstream_gene_variant | 0.69 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.8 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.8 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.75 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 0.72 | isoniazid | |
hadA | 731840 | c.-90G>C | upstream_gene_variant | 0.52 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.47 | isoniazid | |
hadA | 731849 | c.-81C>T | upstream_gene_variant | 0.42 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 0.38 | isoniazid | |
hadA | 732238 | c.309G>T | synonymous_variant | 0.5 | isoniazid | |
hadA | 732250 | c.321C>T | synonymous_variant | 0.66 | isoniazid | |
hadA | 732259 | c.330T>C | synonymous_variant | 0.71 | isoniazid | |
hadA | 732270 | p.Glu114Val | missense_variant | 0.75 | isoniazid | |
hadA | 732272 | p.Ala115Ser | missense_variant | 0.76 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.79 | isoniazid | |
hadA | 732304 | c.375C>T | synonymous_variant | 0.8 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.8 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.81 | isoniazid | |
hadA | 732319 | c.390G>A | synonymous_variant | 0.81 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.8 | isoniazid | |
hadA | 732329 | p.Leu134Ile | missense_variant | 0.84 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.8 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.78 | isoniazid | |
hadA | 732388 | c.459T>C | synonymous_variant | 0.72 | isoniazid | |
hadA | 732389 | p.Ser154Ala | missense_variant | 0.72 | isoniazid | |
hadA | 732392 | p.Asp155Asn | missense_variant | 0.72 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.72 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.75 | isoniazid | |
hadA | 732401 | p.Ala158Pro | missense_variant | 0.75 | isoniazid | |
nusG | 734078 | c.-176C>A | upstream_gene_variant | 0.46 | rifampicin | |
nusG | 734093 | c.-161A>C | upstream_gene_variant | 0.49 | rifampicin | |
nusG | 734102 | c.-152G>C | upstream_gene_variant | 0.48 | rifampicin | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.48 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.49 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.48 | rifampicin | Uncertain significance |
nusG | 734123 | c.-131C>T | upstream_gene_variant | 0.49 | rifampicin | |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.48 | rifampicin | |
nusG | 734132 | c.-122G>C | upstream_gene_variant | 0.49 | rifampicin | |
nusG | 734135 | c.-119G>T | upstream_gene_variant | 0.48 | rifampicin | |
nusG | 734144 | c.-110G>T | upstream_gene_variant | 0.47 | rifampicin | |
nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.51 | rifampicin | |
nusG | 734352 | c.99T>C | synonymous_variant | 0.53 | rifampicin | |
nusG | 734362 | p.Ala37Thr | missense_variant | 0.61 | rifampicin | |
nusG | 734403 | c.150C>T | synonymous_variant | 0.68 | rifampicin | |
nusG | 734407 | p.Val52Ile | missense_variant | 0.71 | rifampicin | |
nusG | 734421 | c.168A>C | synonymous_variant | 0.77 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.78 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.84 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.84 | rifampicin | |
nusG | 734460 | c.207G>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
nusG | 734472 | c.219T>C | synonymous_variant | 0.79 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
nusG | 734478 | c.225C>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
nusG | 734481 | c.228C>T | synonymous_variant | 0.79 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
nusG | 734538 | c.285C>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.8 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.77 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.79 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.77 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.69 | rifampicin | |
nusG | 734631 | c.378G>C | synonymous_variant | 0.71 | rifampicin | |
nusG | 734637 | c.384G>C | synonymous_variant | 0.64 | rifampicin | |
nusG | 734643 | c.390G>C | synonymous_variant | 0.58 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 0.47 | rifampicin | |
nusG | 734658 | c.405A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R |
nusG | 734661 | c.408A>C | synonymous_variant | 0.47 | rifampicin | |
nusG | 734664 | c.411T>G | synonymous_variant | 0.47 | rifampicin | |
nusG | 734667 | c.414C>T | synonymous_variant | 0.5 | rifampicin | |
nusG | 734673 | c.420A>G | synonymous_variant | 0.54 | rifampicin | |
nusG | 734679 | c.426C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
nusG | 734680 | p.Ala143Thr | missense_variant | 0.54 | rifampicin | |
nusG | 734709 | c.456T>G | synonymous_variant | 0.8 | rifampicin | |
nusG | 734726 | p.Arg158Lys | missense_variant | 0.79 | rifampicin | |
nusG | 734733 | c.480T>C | synonymous_variant | 0.78 | rifampicin | |
nusG | 734742 | c.489T>C | synonymous_variant | 0.86 | rifampicin | |
nusG | 734750 | p.Ser166Thr | missense_variant | 0.88 | rifampicin | |
nusG | 734757 | c.504T>C | synonymous_variant | 0.85 | rifampicin | |
nusG | 734771 | p.Ala173Val | missense_variant | 0.84 | rifampicin | |
nusG | 734781 | c.528A>G | synonymous_variant | 0.77 | rifampicin | |
nusG | 734784 | c.531G>A | synonymous_variant | 0.76 | rifampicin | |
nusG | 734787 | c.534T>C | synonymous_variant | 0.76 | rifampicin | |
nusG | 734791 | p.Val180Thr | missense_variant | 0.73 | rifampicin | |
nusG | 734794 | p.Val181Ile | missense_variant | 0.75 | rifampicin | Uncertain significance |
nusG | 734814 | c.561G>C | synonymous_variant | 0.74 | rifampicin | |
nusG | 734826 | c.573A>G | synonymous_variant | 0.72 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
nusG | 734841 | c.588G>A | synonymous_variant | 0.74 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.69 | rifampicin | |
nusG | 734853 | c.600A>G | synonymous_variant | 0.69 | rifampicin | |
nusG | 734865 | c.612G>C | synonymous_variant | 0.71 | rifampicin | |
nusG | 734870 | p.Ser206Asn | missense_variant | 0.69 | rifampicin | |
nusG | 734882 | p.Ala210Gly | missense_variant | 0.64 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 0.53 | rifampicin | |
nusG | 734910 | c.657C>G | synonymous_variant | 0.4 | rifampicin | |
nusG | 734913 | c.660C>G | synonymous_variant | 0.43 | rifampicin | |
mmaA3 | 738333 | c.-184C>A | upstream_gene_variant | 0.41 | isoniazid | |
mmaA3 | 738339 | c.-190G>C | upstream_gene_variant | 0.35 | isoniazid | |
mmaA3 | 738345 | c.-198_-196delCTGinsGCA | upstream_gene_variant | 0.42 | isoniazid | |
mmaA3 | 738348 | c.-199G>C | upstream_gene_variant | 0.5 | isoniazid | |
rpoB | 760067 | c.261G>C | synonymous_variant | 0.81 | rifampicin | |
rpoB | 760070 | c.264T>G | synonymous_variant | 0.81 | rifampicin | |
rpoB | 760088 | c.282C>G | synonymous_variant | 0.81 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.86 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.86 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.84 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.82 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.89 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.89 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.87 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760356 | p.Thr184Ser | missense_variant | 0.87 | rifampicin | Uncertain significance |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.82 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.81 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.79 | rifampicin | |
rpoB | 760383 | c.577C>T | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoB | 760460 | c.654G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 760487 | c.681G>C | synonymous_variant | 0.85 | rifampicin | |
rpoB | 760519 | p.Thr238Ser | missense_variant | 0.85 | rifampicin | |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.84 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.81 | rifampicin | |
rpoB | 760547 | c.741G>T | synonymous_variant | 0.84 | rifampicin | |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.81 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.88 | rifampicin | |
rpoB | 760607 | c.801G>A | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.8 | rifampicin | |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 760721 | c.915C>G | synonymous_variant | 0.7 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760755 | p.His317Asn | missense_variant | 0.69 | rifampicin | |
rpoB | 760760 | c.954C>G | synonymous_variant | 0.7 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.76 | rifampicin | |
rpoB | 760784 | c.978G>C | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.74 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.76 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Ala | missense_variant | 0.78 | rifampicin | |
rpoB | 760859 | c.1053T>C | synonymous_variant | 0.79 | rifampicin | |
rpoB | 760862 | c.1056G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 760869 | p.Val355Thr | missense_variant | 0.8 | rifampicin | |
rpoB | 760877 | c.1071G>A | synonymous_variant | 0.81 | rifampicin | |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.77 | rifampicin | |
rpoB | 760892 | c.1086C>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.81 | rifampicin | |
rpoB | 760920 | c.1114C>T | synonymous_variant | 0.8 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.78 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.78 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 760964 | c.1158C>T | synonymous_variant | 0.74 | rifampicin | |
rpoB | 760973 | c.1167G>C | synonymous_variant | 0.76 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.83 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761126 | c.1320G>A | synonymous_variant | 0.83 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 761147 | c.1341C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.83 | rifampicin | |
rpoB | 761165 | c.1359_1362delGCCCinsCCCG | synonymous_variant | 0.84 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761234 | c.1428G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761258 | c.1452G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761286 | c.1480C>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761289 | p.Ser495Ala | missense_variant | 0.94 | rifampicin | |
rpoB | 761292 | p.Val496Thr | missense_variant | 0.85 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 761345 | c.1539G>C | synonymous_variant | 0.78 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.79 | rifampicin | |
rpoB | 761358 | p.Val518Ile | missense_variant | 0.79 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.77 | rifampicin | |
rpoB | 761465 | c.1659G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.63 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.77 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.84 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.83 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 761561 | c.1755C>G | synonymous_variant | 0.85 | rifampicin | |
rpoB | 761564 | c.1758G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.86 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761651 | c.1845C>T | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 761660 | c.1854G>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761675 | c.1869G>T | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761711 | c.1905C>G | synonymous_variant | 0.91 | rifampicin | |
rpoB | 761717 | c.1911C>G | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 0.84 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.79 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.76 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.68 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.59 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.58 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.58 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.58 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761867 | c.2061C>G | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761870 | p.Asp688Glu | missense_variant | 0.69 | rifampicin | |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.69 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.82 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.86 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.9 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.9 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.88 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 761969 | c.2163G>A | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 761972 | c.2166C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.87 | rifampicin | |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.86 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.85 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.83 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.83 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.85 | rifampicin | |
rpoB | 762149 | c.2343G>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.9 | rifampicin | |
rpoB | 762284 | c.2478G>T | synonymous_variant | 0.88 | rifampicin | |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 762296 | c.2490G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.72 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 762380 | c.-990T>C | upstream_gene_variant | 0.74 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.72 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.74 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.83 | rifampicin | |
rpoC | 762443 | c.-927G>C | upstream_gene_variant | 0.82 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762452 | c.2646G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.8 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.84 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.83 | rifampicin | Uncertain significance |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.85 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.81 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.78 | rifampicin | |
rpoC | 762545 | c.-825C>G | upstream_gene_variant | 0.72 | rifampicin | |
rpoC | 762575 | c.-795C>T | upstream_gene_variant | 0.59 | rifampicin | |
rpoC | 762581 | c.-789T>C | upstream_gene_variant | 0.44 | rifampicin | |
rpoC | 762582 | c.-788T>C | upstream_gene_variant | 0.44 | rifampicin | |
rpoB | 762750 | p.Leu982Met | missense_variant | 0.5 | rifampicin | |
rpoB | 762753 | c.2947T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 762758 | c.-612G>C | upstream_gene_variant | 0.62 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 0.69 | rifampicin | Uncertain significance |
rpoB | 762788 | c.2982G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.69 | rifampicin | Uncertain significance |
rpoB | 762795 | p.Asp997Asn | missense_variant | 0.7 | rifampicin | Uncertain significance |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.72 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.77 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 762833 | c.3027C>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 762836 | c.3030C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoB | 762894 | c.3088C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 762917 | c.-453C>T | upstream_gene_variant | 0.82 | rifampicin | |
rpoC | 762947 | c.-423C>G | upstream_gene_variant | 0.82 | rifampicin | |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.87 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 763049 | c.-321G>A | upstream_gene_variant | 0.8 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 763139 | c.-231C>T | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.71 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 763181 | c.-189G>C | upstream_gene_variant | 0.73 | rifampicin | |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.69 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.7 | rifampicin | |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.72 | rifampicin | |
rpoC | 763262 | c.-108C>A | upstream_gene_variant | 0.62 | rifampicin | |
rpoB | 763268 | c.3462C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.32 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.39 | rifampicin | Uncertain significance |
rpoC | 763402 | c.33C>T | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 763408 | c.39T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.75 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.83 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 763576 | c.207C>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.84 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 763658 | c.289_291delCTTinsTTG | synonymous_variant | 0.78 | rifampicin | |
rpoC | 763672 | c.303C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 763705 | c.336G>T | synonymous_variant | 0.8 | rifampicin | |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.81 | rifampicin | |
rpoC | 763714 | c.345G>T | synonymous_variant | 0.82 | rifampicin | |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.81 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.84 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.83 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.83 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.88 | rifampicin | |
rpoC | 763781 | p.Ser138Ala | missense_variant | 0.86 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.81 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 763835 | p.Ala156Leu | missense_variant | 0.71 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.72 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.73 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.67 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.67 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 763885 | c.516C>A | synonymous_variant | 0.71 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.72 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.71 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 763951 | c.582G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.82 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.81 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.83 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.78 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.67 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.7 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.79 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.81 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.79 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.78 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 764182 | c.813C>T | synonymous_variant | 0.79 | rifampicin | |
rpoC | 764198 | c.829C>T | synonymous_variant | 0.78 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 764213 | p.Arg282Lys | missense_variant | 0.8 | rifampicin | Uncertain significance |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 764329 | c.960C>T | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 764359 | c.990C>G | synonymous_variant | 0.63 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 764383 | c.1014C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 764435 | c.1066_1068delAGGinsCGA | synonymous_variant | 0.86 | rifampicin | |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.88 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.83 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.83 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 764485 | c.1116G>C | synonymous_variant | 0.84 | rifampicin | |
rpoC | 764491 | c.1122G>T | synonymous_variant | 0.81 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 0.75 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.8 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 764734 | c.1365C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 764758 | c.1389C>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 764915 | c.1546C>T | synonymous_variant | 0.86 | rifampicin | |
rpoC | 764932 | c.1563C>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765278 | c.1909C>T | synonymous_variant | 0.53 | rifampicin | |
rpoC | 765292 | c.1923G>T | synonymous_variant | 0.56 | rifampicin | |
rpoC | 765317 | c.1948_1950delCTAinsTTG | synonymous_variant | 0.46 | rifampicin | |
rpoC | 765326 | p.His653Ala | missense_variant | 0.46 | rifampicin | Uncertain significance |
rpoC | 765330 | p.Ser654Asn | missense_variant | 0.5 | rifampicin | Uncertain significance |
rpoC | 765346 | c.1977C>T | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 765370 | c.2001G>T | synonymous_variant | 0.78 | rifampicin | |
rpoC | 765371 | c.2002C>T | synonymous_variant | 0.78 | rifampicin | |
rpoC | 765379 | c.2010G>A | synonymous_variant | 0.81 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.81 | rifampicin | Uncertain significance |
rpoC | 765395 | c.2026C>T | synonymous_variant | 0.84 | rifampicin | |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.79 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.78 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 765454 | c.2085C>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 765466 | c.2097C>T | synonymous_variant | 0.84 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.93 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.89 | rifampicin | |
rpoC | 765550 | c.2181C>T | synonymous_variant | 0.86 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765583 | c.2214G>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.83 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.81 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.87 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.87 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.89 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.81 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.82 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.8 | rifampicin | |
rpoC | 765811 | c.2442T>G | synonymous_variant | 0.81 | rifampicin | |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 766009 | c.2640G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.82 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.81 | rifampicin | |
rpoC | 766061 | p.Val898Leu | missense_variant | 0.81 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.84 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.85 | rifampicin | |
rpoC | 766147 | c.2778C>T | synonymous_variant | 0.79 | rifampicin | |
rpoC | 766148 | p.Thr927Ala | missense_variant | 0.79 | rifampicin | Uncertain significance |
rpoC | 766153 | c.2784C>T | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 766178 | p.Ile937Val | missense_variant | 0.59 | rifampicin | |
rpoC | 766247 | p.Val960Ile | missense_variant | 0.5 | rifampicin | |
rpoC | 766258 | c.2889T>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 766270 | c.2901G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.67 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.67 | rifampicin | |
rpoC | 766288 | c.2919C>T | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766294 | c.2925C>T | synonymous_variant | 0.75 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.83 | rifampicin | |
rpoC | 766321 | c.2952C>G | synonymous_variant | 0.84 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.87 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.9 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.87 | rifampicin | |
rpoC | 766459 | c.3090G>T | synonymous_variant | 0.91 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.9 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.87 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 0.87 | rifampicin | Uncertain significance |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoC | 766501 | c.3132G>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 766531 | c.3162G>T | synonymous_variant | 0.73 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.79 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.78 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.78 | rifampicin | |
rpoC | 766588 | c.3219G>A | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.77 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 766597 | c.3228C>T | synonymous_variant | 0.79 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.85 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 0.92 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766690 | c.3321G>C | synonymous_variant | 0.88 | rifampicin | |
rpoC | 766693 | c.3324C>T | synonymous_variant | 0.87 | rifampicin | |
rpoC | 766714 | c.3345G>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.85 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766777 | c.3408C>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766781 | p.Val1138Thr | missense_variant | 0.85 | rifampicin | |
rpoC | 766801 | c.3432C>A | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 766846 | c.3477C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 766858 | c.3489C>G | synonymous_variant | 0.73 | rifampicin | |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.73 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766915 | c.3546C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 766921 | c.3552G>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766934 | p.Glu1189Ser | missense_variant | 0.52 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>T | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.88 | rifampicin | |
rpoC | 767059 | c.3690T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 767080 | c.3711G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 767104 | c.3735C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 767105 | p.Asn1246Gln | missense_variant | 0.81 | rifampicin | Uncertain significance |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.79 | rifampicin | |
rpoC | 767152 | c.3783T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 767176 | c.3807C>T | synonymous_variant | 0.86 | rifampicin | |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.86 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.65 | rifampicin | |
rpoC | 767270 | p.Thr1301Ala | missense_variant | 0.67 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775856 | c.2625T>C | synonymous_variant | 0.67 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775864 | p.Ala873Ser | missense_variant | 0.56 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775865 | c.2616T>A | synonymous_variant | 0.56 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775883 | p.Ile866Leu | missense_variant | 0.63 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775886 | c.2595A>C | synonymous_variant | 0.63 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775901 | c.2580G>A | synonymous_variant | 0.58 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.65 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775913 | c.2568C>G | synonymous_variant | 0.67 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 0.67 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.51 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.39 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775973 | c.2506_2508delTTGinsCTC | synonymous_variant | 0.29 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.47 | bedaquiline | |
clofazimine | ||||||
rpsL | 781128 | c.-432C>G | upstream_gene_variant | 0.67 | streptomycin | |
rpsL | 781134 | c.-426T>C | upstream_gene_variant | 0.67 | streptomycin | |
rpsL | 781138 | c.-422_-421delCAinsGC | upstream_gene_variant | 0.67 | streptomycin | |
rpsL | 781143 | c.-417T>C | upstream_gene_variant | 0.67 | streptomycin | |
rpsL | 781147 | c.-413T>C | upstream_gene_variant | 0.63 | streptomycin | |
rpsL | 781153 | c.-407G>T | upstream_gene_variant | 0.65 | streptomycin | |
rpsL | 781158 | c.-402C>G | upstream_gene_variant | 0.68 | streptomycin | |
rpsL | 781164 | c.-396T>C | upstream_gene_variant | 0.75 | streptomycin | |
rpsL | 781182 | c.-378G>T | upstream_gene_variant | 0.82 | streptomycin | |
rpsL | 781197 | c.-363A>G | upstream_gene_variant | 0.83 | streptomycin | |
rpsL | 781203 | c.-357C>G | upstream_gene_variant | 0.79 | streptomycin | |
rpsL | 781209 | c.-351C>G | upstream_gene_variant | 0.75 | streptomycin | |
rpsL | 781218 | c.-342C>G | upstream_gene_variant | 0.79 | streptomycin | |
rpsL | 781224 | c.-336T>C | upstream_gene_variant | 0.82 | streptomycin | |
rpsL | 781230 | c.-330T>C | upstream_gene_variant | 0.82 | streptomycin | |
rpsL | 781234 | c.-326G>C | upstream_gene_variant | 0.82 | streptomycin | |
rpsL | 781240 | c.-320A>T | upstream_gene_variant | 0.85 | streptomycin | |
rpsL | 781266 | c.-294G>C | upstream_gene_variant | 0.75 | streptomycin | |
rpsL | 781270 | c.-290A>C | upstream_gene_variant | 0.64 | streptomycin | |
rpsL | 781571 | c.12C>T | synonymous_variant | 0.68 | streptomycin | |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781598 | c.39G>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781605 | p.Ile16Val | missense_variant | 0.85 | streptomycin | Uncertain significance |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.88 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.89 | streptomycin | Not assoc w R - Interim |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.91 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.89 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.84 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.86 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.87 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.87 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.87 | streptomycin | |
rpsL | 781805 | c.246G>A | synonymous_variant | 0.89 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.88 | streptomycin | |
rpsL | 781814 | c.255C>T | synonymous_variant | 0.87 | streptomycin | |
rpsL | 781817 | c.258G>C | synonymous_variant | 0.86 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.88 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.88 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.86 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.84 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.84 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.85 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.81 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.8 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.81 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.74 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.7 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.84 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.84 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.83 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.85 | linezolid | |
rplC | 800594 | c.-215C>T | upstream_gene_variant | 0.87 | linezolid | |
rplC | 800600 | c.-209G>T | upstream_gene_variant | 0.85 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.85 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.91 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.83 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.83 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.82 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.8 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.82 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 0.77 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.76 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.72 | linezolid | |
rplC | 800798 | c.-11_-8delTGGAinsC | upstream_gene_variant | 0.6 | linezolid | |
rplC | 800806 | c.-3G>C | upstream_gene_variant | 0.58 | linezolid | |
rplC | 800807 | c.-2C>T | upstream_gene_variant | 0.58 | linezolid | |
rplC | 800808 | c.-1A>C | upstream_gene_variant | 0.58 | linezolid | Uncertain significance |
rplC | 800815 | c.7C>A | synonymous_variant | 0.56 | linezolid | |
rplC | 800820 | c.12G>A | synonymous_variant | 0.58 | linezolid | |
rplC | 800829 | c.21C>G | synonymous_variant | 0.66 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.67 | linezolid | |
rplC | 800856 | c.48A>G | synonymous_variant | 0.6 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.48 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.45 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.43 | linezolid | |
rplC | 800875 | p.Val23Ile | missense_variant | 0.43 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.58 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.68 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.68 | linezolid | |
rplC | 800904 | c.96G>C | synonymous_variant | 0.79 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.79 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.73 | linezolid | |
rplC | 800922 | c.114C>G | synonymous_variant | 0.63 | linezolid | |
rplC | 800928 | c.120C>T | synonymous_variant | 0.61 | linezolid | |
rplC | 800931 | c.123G>C | synonymous_variant | 0.61 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.65 | linezolid | |
rplC | 800939 | p.Arg44Gln | missense_variant | 0.61 | linezolid | |
rplC | 800946 | c.138T>C | synonymous_variant | 0.69 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 0.72 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 0.79 | linezolid | Not assoc w R - Interim |
rplC | 800982 | c.174C>T | synonymous_variant | 0.75 | linezolid | |
rplC | 800985 | c.177A>C | synonymous_variant | 0.75 | linezolid | |
rplC | 801004 | p.Leu66Val | missense_variant | 0.56 | linezolid | |
rplC | 801009 | c.201A>C | synonymous_variant | 0.5 | linezolid | |
rplC | 801019 | p.Thr71Ala | missense_variant | 0.56 | linezolid | |
rplC | 801027 | c.219C>G | synonymous_variant | 0.56 | linezolid | |
rplC | 801033 | c.225C>G | synonymous_variant | 0.53 | linezolid | |
rplC | 801039 | c.231A>G | synonymous_variant | 0.5 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 0.5 | linezolid | |
rplC | 801136 | p.Ser110Ala | missense_variant | 0.53 | linezolid | |
rplC | 801147 | c.339T>C | synonymous_variant | 0.61 | linezolid | |
rplC | 801150 | c.342G>C | synonymous_variant | 0.58 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 0.6 | linezolid | |
rplC | 801156 | c.348T>C | synonymous_variant | 0.65 | linezolid | |
rplC | 801168 | c.360C>A | synonymous_variant | 0.67 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 0.67 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.67 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.67 | linezolid | |
rplC | 801205 | p.Arg133Ser | missense_variant | 0.71 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 0.7 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.58 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.58 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.59 | linezolid | |
rplC | 801258 | c.450C>G | synonymous_variant | 0.57 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.56 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.65 | linezolid | |
rplC | 801307 | p.Ala167Ser | missense_variant | 0.6 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.63 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.58 | linezolid | Not assoc w R - Interim |
rplC | 801323 | p.Asn172Ser | missense_variant | 0.58 | linezolid | |
rplC | 801327 | c.519C>T | synonymous_variant | 0.58 | linezolid | |
rplC | 801330 | c.522G>C | synonymous_variant | 0.58 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.62 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.68 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.74 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.76 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.79 | linezolid | |
rplC | 801396 | c.588T>C | synonymous_variant | 0.71 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.67 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.69 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.69 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.69 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.56 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.54 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1303441 | c.511T>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303464 | c.534A>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303470 | c.540T>G | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303480 | p.Gln184Glu | missense_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303488 | c.558G>C | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303492 | c.562T>C | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.74 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303542 | c.612C>G | synonymous_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.79 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303599 | c.669C>T | synonymous_variant | 0.69 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303647 | c.717G>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.74 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.77 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303728 | c.798G>C | synonymous_variant | 0.86 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.85 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.85 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.85 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.83 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.81 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>T | synonymous_variant | 0.82 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.84 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303794 | c.864A>G | synonymous_variant | 0.86 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.84 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.85 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.88 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.86 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303897 | c.967C>T | synonymous_variant | 0.72 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.66 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.63 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303921 | p.Ile331Val | missense_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303935 | c.1005G>C | synonymous_variant | 0.63 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303965 | c.1035G>A | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303969 | p.Val347Ile | missense_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304001 | c.1071C>T | synonymous_variant | 0.66 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.63 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304049 | c.1119T>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304050 | c.1120T>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304058 | c.1128G>A | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304079 | c.1149A>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304088 | c.1158C>T | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304097 | c.1167G>T | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304103 | c.1173G>A | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304115 | c.1185A>G | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304127 | c.1197A>G | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304137 | p.Ala403Ser | missense_variant | 0.68 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304142 | c.1212G>C | synonymous_variant | 0.81 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304154 | c.1224G>A | synonymous_variant | 0.87 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304157 | c.1227G>C | synonymous_variant | 0.87 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304162 | p.Arg411Gln | missense_variant | 0.88 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304169 | c.1239T>C | synonymous_variant | 0.93 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304174 | p.Val415Ala | missense_variant | 0.94 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304205 | c.1275C>T | synonymous_variant | 0.85 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304226 | c.1296C>G | synonymous_variant | 0.82 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304232 | c.1302G>C | synonymous_variant | 0.82 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304241 | c.1311G>A | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304520 | c.1590A>C | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304523 | c.1593G>T | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304530 | p.Ser534Thr | missense_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304533 | c.1603_1605delTTGinsCTA | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304544 | p.Asp538Glu | missense_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304545 | p.Val539Thr | missense_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304556 | c.1626C>T | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304565 | c.1635C>A | synonymous_variant | 0.68 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.74 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.74 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>G | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>C | synonymous_variant | 0.69 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304790 | c.1860C>G | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304796 | c.1866G>A | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.77 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304826 | c.1896G>C | synonymous_variant | 0.77 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.75 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.82 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304880 | c.1950C>T | synonymous_variant | 0.8 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.82 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.79 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.82 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.84 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.85 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.86 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053_2055delCTGinsTTA | synonymous_variant | 0.84 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.84 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | c.2065T>C | synonymous_variant | 0.84 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305014 | p.Thr695Ser | missense_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305021 | c.2091C>A | synonymous_variant | 0.8 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.79 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305045 | c.2115A>G | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305051 | c.2121G>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305075 | c.2145T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305078 | c.2148A>G | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305092 | p.Ala721Gly | missense_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305096 | c.2166T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305099 | c.2169T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305114 | c.2184T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305117 | c.2187T>C | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305126 | c.2196T>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305135 | c.2205C>T | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305144 | c.2214G>A | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305150 | c.2220C>G | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305173 | p.Asn748Ser | missense_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305177 | c.2247A>G | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305181 | c.2251T>C | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305186 | c.2256C>T | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305195 | c.2265T>C | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305199 | p.Ala757Ser | missense_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305204 | c.2274C>T | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305215 | p.Ser762Thr | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305219 | c.2289T>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305231 | c.2301C>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305237 | c.2307A>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305240 | c.2310T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305243 | c.2313T>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305252 | c.2322G>A | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305348 | c.2418C>T | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305361 | c.2431C>T | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305375 | c.2445C>G | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305396 | c.2466C>G | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305400 | p.His824Tyr | missense_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305405 | c.2475A>C | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305417 | c.2487C>G | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
atpE | 1460816 | c.-229T>C | upstream_gene_variant | 0.72 | bedaquiline | |
atpE | 1460831 | c.-214T>C | upstream_gene_variant | 0.66 | bedaquiline | |
atpE | 1460832 | c.-213C>T | upstream_gene_variant | 0.66 | bedaquiline | |
atpE | 1460840 | c.-205A>G | upstream_gene_variant | 0.66 | bedaquiline | |
atpE | 1460852 | c.-193C>G | upstream_gene_variant | 0.6 | bedaquiline | |
atpE | 1460855 | c.-190T>C | upstream_gene_variant | 0.62 | bedaquiline | |
atpE | 1460858 | c.-187C>G | upstream_gene_variant | 0.57 | bedaquiline | |
atpE | 1460861 | c.-184C>G | upstream_gene_variant | 0.54 | bedaquiline | |
atpE | 1461158 | c.114T>C | synonymous_variant | 0.58 | bedaquiline | |
atpE | 1461159 | p.Val39Ile | missense_variant | 0.6 | bedaquiline | Uncertain significance |
atpE | 1461170 | c.126A>G | synonymous_variant | 0.58 | bedaquiline | |
atpE | 1461185 | c.141G>C | synonymous_variant | 0.6 | bedaquiline | |
atpE | 1461189 | c.145C>T | synonymous_variant | 0.58 | bedaquiline | |
atpE | 1461194 | c.150C>T | synonymous_variant | 0.54 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.53 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.46 | bedaquiline | |
atpE | 1461233 | c.189A>C | synonymous_variant | 0.39 | bedaquiline | |
atpE | 1461251 | c.207G>C | synonymous_variant | 0.3 | bedaquiline | |
atpE | 1461254 | c.210T>C | synonymous_variant | 0.26 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.74 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.66 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.55 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.53 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.53 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.53 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.54 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.6 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.64 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.83 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.83 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.86 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.86 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.83 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.87 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.88 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.86 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473288 | n.1443C>T | non_coding_transcript_exon_variant | 0.81 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.8 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.8 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473752 | n.95G>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1473831 | n.174G>A | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473936 | n.279A>G | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473944 | n.287G>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1473966 | n.309T>C | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1473971 | n.314G>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1473981 | n.324_325insT | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
linezolid | ||||||
rrl | 1474036 | n.379G>A | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1474040 | n.383G>A | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1474110 | n.453A>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.634_649delTTTCCTCTCCGGAGGAinsC | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.76 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1474964 | n.1307T>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1474969 | n.1312G>A | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1475007 | n.1350C>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1475009 | n.1352G>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1475016 | n.1359C>G | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475028 | n.1371G>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1475409 | n.1752T>C | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475652 | n.1995C>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.86 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.76 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476717 | n.3060C>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
linezolid | ||||||
rrl | 1476746 | n.3089T>C | non_coding_transcript_exon_variant | 0.76 | capreomycin | |
linezolid | ||||||
rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1476770 | n.3113T>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1476771 | n.3114G>A | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
inhA | 1673499 | c.-703T>C | upstream_gene_variant | 0.77 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1673505 | c.-697A>C | upstream_gene_variant | 0.81 | isoniazid | |
ethionamide | ||||||
inhA | 1673517 | c.-685G>A | upstream_gene_variant | 0.84 | isoniazid | |
ethionamide | ||||||
inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.93 | isoniazid | |
ethionamide | ||||||
inhA | 1673565 | c.-637G>T | upstream_gene_variant | 0.86 | isoniazid | |
ethionamide | ||||||
inhA | 1673569 | c.-633G>A | upstream_gene_variant | 0.85 | isoniazid | |
ethionamide | ||||||
inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.76 | isoniazid | |
ethionamide | ||||||
inhA | 1673580 | c.-622T>C | upstream_gene_variant | 0.73 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1673710 | c.-492_-490delCTAinsGTC | upstream_gene_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1673724 | c.-478A>G | upstream_gene_variant | 0.7 | isoniazid | |
ethionamide | ||||||
inhA | 1673730 | c.-472C>T | upstream_gene_variant | 0.68 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1673733 | c.-469G>C | upstream_gene_variant | 0.68 | isoniazid | |
ethionamide | ||||||
inhA | 1673748 | c.-454A>G | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1673749 | c.-453_-452delAAinsCG | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1673758 | c.-444_-442delAAGinsCAA | upstream_gene_variant | 0.63 | isoniazid | |
ethionamide | ||||||
inhA | 1673890 | c.-312G>T | upstream_gene_variant | 0.56 | isoniazid | |
ethionamide | ||||||
inhA | 1673901 | c.-301A>C | upstream_gene_variant | 0.67 | isoniazid | |
ethionamide | ||||||
inhA | 1673905 | c.-297T>G | upstream_gene_variant | 0.67 | isoniazid | |
ethionamide | ||||||
inhA | 1673916 | c.-286A>T | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1673917 | c.-285_-283delGTGinsCTC | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1673922 | c.-280T>C | upstream_gene_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1673934 | c.-268C>T | upstream_gene_variant | 0.74 | isoniazid | |
ethionamide | ||||||
inhA | 1673941 | c.-261G>T | upstream_gene_variant | 0.75 | isoniazid | |
ethionamide | ||||||
inhA | 1673946 | c.-256C>G | upstream_gene_variant | 0.77 | isoniazid | |
ethionamide | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.79 | isoniazid | |
ethionamide | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1673962 | c.-240_-238delAACinsGGG | upstream_gene_variant | 0.56 | isoniazid | |
ethionamide | ||||||
inhA | 1673976 | c.-226T>C | upstream_gene_variant | 0.62 | isoniazid | |
ethionamide | ||||||
inhA | 1674012 | c.-190C>G | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1674024 | c.-178T>C | upstream_gene_variant | 0.7 | isoniazid | |
ethionamide | ||||||
inhA | 1674037 | c.-165_-163delCAGinsGCC | upstream_gene_variant | 0.7 | isoniazid | |
ethionamide | ||||||
inhA | 1674049 | c.-153C>G | upstream_gene_variant | 0.73 | isoniazid | |
ethionamide | ||||||
inhA | 1674054 | c.-148T>C | upstream_gene_variant | 0.73 | isoniazid | |
ethionamide | ||||||
inhA | 1674060 | c.-142A>C | upstream_gene_variant | 0.71 | isoniazid | |
ethionamide | ||||||
inhA | 1674079 | c.-123C>G | upstream_gene_variant | 0.74 | isoniazid | |
ethionamide | ||||||
inhA | 1674084 | c.-118C>G | upstream_gene_variant | 0.72 | isoniazid | |
ethionamide | ||||||
inhA | 1674117 | c.-85C>G | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1674123 | c.-79T>C | upstream_gene_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674129 | c.-73C>T | upstream_gene_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674132 | c.-70T>C | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1674136 | c.-66T>G | upstream_gene_variant | 0.57 | isoniazid | |
ethionamide | ||||||
inhA | 1674331 | c.130C>T | synonymous_variant | 0.59 | isoniazid | |
ethionamide | ||||||
inhA | 1674336 | c.135G>C | synonymous_variant | 0.61 | isoniazid | |
ethionamide | ||||||
inhA | 1674352 | p.Thr51Ala | missense_variant | 0.58 | isoniazid | |
ethionamide | Uncertain significance | |||||
inhA | 1674368 | p.Ala56Glu | missense_variant | 0.54 | isoniazid | |
ethionamide | ||||||
inhA | 1674375 | c.174C>G | synonymous_variant | 0.53 | isoniazid | |
ethionamide | ||||||
inhA | 1674382 | p.Leu61Ile | missense_variant | 0.56 | isoniazid | |
ethionamide | ||||||
inhA | 1674462 | c.261G>A | synonymous_variant | 0.36 | isoniazid | |
ethionamide | ||||||
inhA | 1674471 | c.270G>T | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674480 | c.279T>C | synonymous_variant | 0.52 | isoniazid | |
ethionamide | ||||||
inhA | 1674486 | c.285T>C | synonymous_variant | 0.54 | isoniazid | |
ethionamide | ||||||
inhA | 1674489 | c.288G>T | synonymous_variant | 0.57 | isoniazid | |
ethionamide | ||||||
inhA | 1674504 | c.303C>G | synonymous_variant | 0.67 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
inhA | 1674540 | c.339C>T | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.72 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.73 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.8 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.8 | isoniazid | |
ethionamide | ||||||
inhA | 1674573 | c.372G>A | synonymous_variant | 0.83 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.8 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.82 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.83 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Val | missense_variant | 0.83 | isoniazid | |
ethionamide | ||||||
inhA | 1674604 | c.403C>T | synonymous_variant | 0.83 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
inhA | 1674627 | c.426T>C | synonymous_variant | 0.78 | isoniazid | |
ethionamide | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 0.81 | isoniazid | |
ethionamide | ||||||
inhA | 1674654 | c.453G>C | synonymous_variant | 0.83 | isoniazid | |
ethionamide | ||||||
inhA | 1674687 | c.486G>C | synonymous_variant | 0.76 | isoniazid | |
ethionamide | ||||||
inhA | 1674690 | c.489C>G | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.81 | isoniazid | |
ethionamide | ||||||
inhA | 1674738 | c.537C>G | synonymous_variant | 0.82 | isoniazid | |
ethionamide | ||||||
inhA | 1674746 | p.Tyr182Ser | missense_variant | 0.79 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.8 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674759 | c.558G>C | synonymous_variant | 0.85 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>G | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
inhA | 1674780 | c.579T>C | synonymous_variant | 0.79 | isoniazid | |
ethionamide | ||||||
inhA | 1674795 | c.594G>C | synonymous_variant | 0.82 | isoniazid | |
ethionamide | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.81 | isoniazid | |
ethionamide | ||||||
inhA | 1674804 | c.603G>C | synonymous_variant | 0.81 | isoniazid | |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674840 | c.639C>G | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.78 | isoniazid | |
ethionamide | ||||||
inhA | 1674855 | c.654C>G | synonymous_variant | 0.73 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
inhA | 1674858 | c.657G>A | synonymous_variant | 0.71 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.8 | isoniazid | |
ethionamide | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.82 | isoniazid | |
ethionamide | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.76 | isoniazid | |
ethionamide | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.76 | isoniazid | |
ethionamide | ||||||
inhA | 1674934 | c.733C>T | synonymous_variant | 0.68 | isoniazid | |
ethionamide | ||||||
inhA | 1674939 | c.738G>C | synonymous_variant | 0.7 | isoniazid | |
ethionamide | ||||||
inhA | 1674942 | c.741T>G | synonymous_variant | 0.7 | isoniazid | |
ethionamide | ||||||
inhA | 1674951 | c.750G>C | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
inhA | 1674960 | c.759C>G | synonymous_variant | 0.62 | isoniazid | |
ethionamide | ||||||
rpsA | 1833541 | c.-1T>C | upstream_gene_variant | 0.92 | pyrazinamide | |
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.88 | pyrazinamide | Uncertain significance |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833595 | c.54T>G | synonymous_variant | 0.88 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.81 | pyrazinamide | |
rpsA | 1833703 | c.162C>T | synonymous_variant | 0.84 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.86 | pyrazinamide | |
rpsA | 1833760 | c.219C>T | synonymous_variant | 0.87 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833772 | c.231C>T | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.88 | pyrazinamide | |
rpsA | 1833835 | c.294C>T | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833844 | c.303C>T | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.91 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.81 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 0.86 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.88 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834093 | c.552G>C | synonymous_variant | 0.73 | pyrazinamide | |
rpsA | 1834102 | c.561T>G | synonymous_variant | 0.77 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.56 | pyrazinamide | |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.57 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.77 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.77 | pyrazinamide | |
rpsA | 1834259 | c.718_720delCTAinsTTG | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834294 | c.753G>T | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834297 | c.756C>G | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.77 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.76 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834378 | c.837T>C | synonymous_variant | 0.87 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834390 | c.849G>A | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.8 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.79 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.8 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.81 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834495 | c.954G>A | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834498 | c.957C>T | synonymous_variant | 0.84 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.83 | pyrazinamide | |
rpsA | 1834603 | c.1062G>A | synonymous_variant | 0.8 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.77 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.78 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.79 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.89 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.9 | pyrazinamide | |
rpsA | 1834759 | c.1218A>C | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.89 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Asn | missense_variant | 0.86 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.81 | pyrazinamide | |
rpsA | 1834828 | c.1287C>G | synonymous_variant | 0.58 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.75 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.74 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.74 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.69 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.71 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.62 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.55 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.57 | linezolid | |
tsnR | 1853459 | c.-147G>T | upstream_gene_variant | 0.5 | linezolid | |
tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.53 | linezolid | |
tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 0.44 | linezolid | |
tsnR | 1853469 | c.-137G>T | upstream_gene_variant | 0.44 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.42 | linezolid | |
tsnR | 1853484 | c.-122_-121delAGinsGC | upstream_gene_variant | 0.39 | linezolid | |
tsnR | 1853492 | c.-114G>A | upstream_gene_variant | 0.39 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917970 | c.31_33delCTAinsTTG | synonymous_variant | 0.42 | capreomycin | |
tlyA | 1917981 | c.42G>C | synonymous_variant | 0.45 | capreomycin | |
tlyA | 1917990 | c.51G>C | synonymous_variant | 0.47 | capreomycin | |
tlyA | 1917993 | c.54A>G | synonymous_variant | 0.5 | capreomycin | Not assoc w R - Interim |
tlyA | 1917996 | c.57A>C | synonymous_variant | 0.5 | capreomycin | |
tlyA | 1918002 | c.63A>G | synonymous_variant | 0.53 | capreomycin | |
tlyA | 1918026 | c.87C>G | synonymous_variant | 0.56 | capreomycin | |
tlyA | 1918029 | c.90C>G | synonymous_variant | 0.56 | capreomycin | |
tlyA | 1918036 | p.Arg33Ser | missense_variant | 0.6 | capreomycin | |
tlyA | 1918048 | p.Leu37Met | missense_variant | 0.64 | capreomycin | |
bacA | 2063538 | c.1191A>G | synonymous_variant | 0.58 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063541 | c.1188A>G | synonymous_variant | 0.61 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063556 | c.1173T>C | synonymous_variant | 0.73 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063565 | c.1164C>T | synonymous_variant | 0.76 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063588 | c.1141T>C | synonymous_variant | 0.8 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063610 | p.Ser373Ala | missense_variant | 0.61 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063613 | c.1116T>G | synonymous_variant | 0.59 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063625 | c.1104G>C | synonymous_variant | 0.59 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063628 | c.1101C>G | synonymous_variant | 0.56 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063640 | c.1089C>T | synonymous_variant | 0.52 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063648 | p.Gln361Lys | missense_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
bacA | 2063649 | c.1080G>C | synonymous_variant | 0.37 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064150 | c.579T>C | synonymous_variant | 0.29 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064155 | p.Val192Ile | missense_variant | 0.4 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
bacA | 2064159 | c.570A>G | synonymous_variant | 0.42 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064165 | c.564T>C | synonymous_variant | 0.44 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064189 | c.540G>C | synonymous_variant | 0.5 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064192 | p.Glu179Asn | missense_variant | 0.5 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064204 | c.525G>T | synonymous_variant | 0.5 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064224 | c.505A>C | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064228 | p.Asp167Glu | missense_variant | 0.4 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064231 | c.498C>G | synonymous_variant | 0.38 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2101920 | c.1123A>C | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.61 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101930 | c.1113C>G | synonymous_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101936 | c.1107G>C | synonymous_variant | 0.65 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101939 | c.1104A>C | synonymous_variant | 0.7 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101960 | c.1083A>T | synonymous_variant | 0.69 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101966 | c.1077T>G | synonymous_variant | 0.77 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101969 | p.Glu358Asp | missense_variant | 0.77 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101972 | c.1071G>C | synonymous_variant | 0.81 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101977 | p.Pro356Ser | missense_variant | 0.8 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101988 | p.Ala352Gly | missense_variant | 0.74 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101990 | c.1053G>C | synonymous_variant | 0.74 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102005 | c.1038G>C | synonymous_variant | 0.67 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102011 | c.1032C>G | synonymous_variant | 0.67 | isoniazid | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
ethionamide | Not assoc w R - Interim | |||||
ndh | 2102218 | c.825C>G | synonymous_variant | 0.5 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102260 | c.783C>T | synonymous_variant | 0.73 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102317 | c.726A>G | synonymous_variant | 0.68 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102328 | p.Leu239Met | missense_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102422 | c.621C>G | synonymous_variant | 0.44 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102443 | p.Ala200Ser | missense_variant | 0.44 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102450 | p.Lys198Arg | missense_variant | 0.41 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102656 | c.387C>T | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
ethionamide | Not assoc w R - Interim | |||||
ndh | 2102671 | c.372T>G | synonymous_variant | 0.47 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102680 | c.363T>C | synonymous_variant | 0.5 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102683 | c.360T>C | synonymous_variant | 0.53 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102686 | c.357G>C | synonymous_variant | 0.53 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102694 | p.Val117Ile | missense_variant | 0.5 | isoniazid | Uncertain significance |
delamanid | Uncertain significance | |||||
ethionamide | Uncertain significance | |||||
ndh | 2102695 | c.348C>T | synonymous_variant | 0.5 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
katG | 2154992 | p.Ser374Ala | missense_variant | 0.63 | isoniazid | |
katG | 2154999 | c.1113A>G | synonymous_variant | 0.7 | isoniazid | |
katG | 2155005 | c.1107C>T | synonymous_variant | 0.72 | isoniazid | Not assoc w R - Interim |
katG | 2155017 | c.1095G>C | synonymous_variant | 0.7 | isoniazid | |
katG | 2155026 | c.1086C>A | synonymous_variant | 0.7 | isoniazid | |
katG | 2155029 | c.1083C>G | synonymous_variant | 0.7 | isoniazid | |
katG | 2155032 | c.1080T>C | synonymous_variant | 0.71 | isoniazid | Not assoc w R - Interim |
katG | 2155054 | p.Tyr353Phe | missense_variant | 0.66 | isoniazid | |
katG | 2155056 | c.1056A>G | synonymous_variant | 0.66 | isoniazid | |
katG | 2155062 | c.1050T>C | synonymous_variant | 0.73 | isoniazid | |
katG | 2155068 | c.1044T>C | synonymous_variant | 0.68 | isoniazid | |
katG | 2155071 | c.1041T>C | synonymous_variant | 0.68 | isoniazid | |
katG | 2155080 | c.1032G>C | synonymous_variant | 0.57 | isoniazid | |
katG | 2155083 | c.1029G>C | synonymous_variant | 0.53 | isoniazid | |
katG | 2155626 | c.486G>T | synonymous_variant | 0.38 | isoniazid | |
katG | 2155632 | c.480A>C | synonymous_variant | 0.4 | isoniazid | |
katG | 2155637 | p.Leu159Ile | missense_variant | 0.42 | isoniazid | |
katG | 2155641 | p.Lys157Asn | missense_variant | 0.42 | isoniazid | Uncertain significance |
katG | 2155659 | p.Val151Leu | missense_variant | 0.52 | isoniazid | |
katG | 2155676 | c.436C>A | synonymous_variant | 0.59 | isoniazid | |
katG | 2155691 | c.421T>C | synonymous_variant | 0.62 | isoniazid | |
katG | 2155716 | c.396T>C | synonymous_variant | 0.68 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.56 | isoniazid | |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2221939 | p.Arg409Gln | missense_variant | 1.0 | bedaquiline | Uncertain significance |
clofazimine | Uncertain significance | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517917 | c.-198G>T | upstream_gene_variant | 0.86 | isoniazid | |
kasA | 2517965 | c.-150C>T | upstream_gene_variant | 0.83 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.78 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.75 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 0.53 | isoniazid | |
kasA | 2518025 | c.-90G>C | upstream_gene_variant | 0.44 | isoniazid | |
kasA | 2518132 | c.18C>T | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518146 | p.Phe11Tyr | missense_variant | 0.65 | isoniazid | |
kasA | 2518152 | p.Ser13Asn | missense_variant | 0.67 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 0.68 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 0.7 | isoniazid | |
kasA | 2518183 | c.69G>A | synonymous_variant | 0.69 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 0.7 | isoniazid | |
kasA | 2518220 | c.106C>T | synonymous_variant | 0.72 | isoniazid | |
kasA | 2518234 | c.120G>A | synonymous_variant | 0.75 | isoniazid | |
kasA | 2518248 | p.Ala45Val | missense_variant | 0.7 | isoniazid | |
kasA | 2518282 | c.168A>G | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518283 | p.Ala57Pro | missense_variant | 0.62 | isoniazid | |
kasA | 2518417 | c.303G>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518426 | c.312T>C | synonymous_variant | 0.42 | isoniazid | |
kasA | 2518429 | c.315A>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518439 | p.Ala109Ser | missense_variant | 0.5 | isoniazid | |
kasA | 2518444 | c.330T>C | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518447 | c.333T>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518459 | c.345T>G | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518462 | c.348A>C | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518465 | c.351T>C | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518468 | c.354A>C | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518475 | c.361A>C | synonymous_variant | 0.61 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.63 | isoniazid | |
kasA | 2518483 | c.369C>T | synonymous_variant | 0.6 | isoniazid | |
kasA | 2518488 | p.Ser125Thr | missense_variant | 0.62 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.71 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.71 | isoniazid | |
kasA | 2518510 | c.396C>T | synonymous_variant | 0.74 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.79 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.77 | isoniazid | |
kasA | 2518534 | c.420G>C | synonymous_variant | 0.83 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.81 | isoniazid | |
kasA | 2518574 | p.Ile154Val | missense_variant | 0.77 | isoniazid | |
kasA | 2518579 | c.465T>C | synonymous_variant | 0.77 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.77 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.76 | isoniazid | |
kasA | 2518606 | c.492G>C | synonymous_variant | 0.7 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.7 | isoniazid | |
kasA | 2518618 | c.504G>C | synonymous_variant | 0.69 | isoniazid | |
kasA | 2518627 | c.513T>C | synonymous_variant | 0.62 | isoniazid | |
kasA | 2518636 | c.522C>G | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518657 | c.543G>A | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.6 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.6 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.65 | isoniazid | |
kasA | 2518688 | p.Val192Phe | missense_variant | 0.66 | isoniazid | |
kasA | 2518705 | c.591T>G | synonymous_variant | 0.66 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.65 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.67 | isoniazid | |
kasA | 2518723 | c.609G>A | synonymous_variant | 0.69 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.81 | isoniazid | |
kasA | 2518768 | c.654C>A | synonymous_variant | 0.82 | isoniazid | |
kasA | 2518771 | c.657C>G | synonymous_variant | 0.81 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.81 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.8 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.81 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.81 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.79 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.82 | isoniazid | |
kasA | 2518834 | c.720C>T | synonymous_variant | 0.78 | isoniazid | |
kasA | 2518837 | c.723G>A | synonymous_variant | 0.77 | isoniazid | |
kasA | 2518853 | p.Leu247Ile | missense_variant | 0.62 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518867 | c.753G>A | synonymous_variant | 0.61 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518882 | c.768C>T | synonymous_variant | 0.54 | isoniazid | |
ahpC | 2726287 | p.Gly32Glu | missense_variant | 0.4 | isoniazid | |
ahpC | 2726303 | c.111T>C | synonymous_variant | 0.42 | isoniazid | |
ahpC | 2726311 | p.Ser40Asn | missense_variant | 0.41 | isoniazid | |
ahpC | 2726315 | p.Asp41Glu | missense_variant | 0.42 | isoniazid | |
ahpC | 2726318 | p.Glu42Asp | missense_variant | 0.41 | isoniazid | |
ahpC | 2726322 | p.Pro44Ala | missense_variant | 0.37 | isoniazid | |
ahpC | 2726336 | c.144G>T | synonymous_variant | 0.42 | isoniazid | |
ahpC | 2726348 | c.156T>C | synonymous_variant | 0.54 | isoniazid | |
ahpC | 2726579 | c.387T>C | synonymous_variant | 0.5 | isoniazid | |
ahpC | 2726591 | c.399C>G | synonymous_variant | 0.58 | isoniazid | |
ahpC | 2726593 | p.Val134Ala | missense_variant | 0.59 | isoniazid | |
ahpC | 2726600 | c.408T>C | synonymous_variant | 0.62 | isoniazid | |
ahpC | 2726612 | c.420C>G | synonymous_variant | 0.68 | isoniazid | |
ahpC | 2726633 | c.441C>G | synonymous_variant | 0.76 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.75 | isoniazid | |
ahpC | 2726651 | c.459G>C | synonymous_variant | 0.77 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.77 | isoniazid | Not assoc w R - Interim |
ahpC | 2726669 | p.Asp159Glu | missense_variant | 0.77 | isoniazid | |
ahpC | 2726675 | c.483A>G | synonymous_variant | 0.75 | isoniazid | |
ahpC | 2726681 | c.489A>C | synonymous_variant | 0.78 | isoniazid | Not assoc w R - Interim |
ahpC | 2726684 | c.492G>A | synonymous_variant | 0.75 | isoniazid | |
ahpC | 2726687 | c.495C>G | synonymous_variant | 0.79 | isoniazid | |
ahpC | 2726696 | c.504C>G | synonymous_variant | 0.79 | isoniazid | |
ahpC | 2726717 | c.525A>G | synonymous_variant | 0.71 | isoniazid | |
folC | 2746308 | p.Arg431Ser | missense_variant | 0.62 | para-aminosalicylic_acid | |
folC | 2746321 | c.1278A>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
folC | 2746335 | p.Gly422Arg | missense_variant | 0.59 | para-aminosalicylic_acid | |
folC | 2746336 | c.1263C>G | synonymous_variant | 0.59 | para-aminosalicylic_acid | |
folC | 2746351 | p.Ala416Ser | missense_variant | 0.63 | para-aminosalicylic_acid | |
folC | 2746360 | c.1239T>C | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
folC | 2746363 | c.1236G>C | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
folC | 2746393 | c.1206C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
folC | 2746558 | c.1041G>C | synonymous_variant | 0.57 | para-aminosalicylic_acid | |
folC | 2746564 | c.1035A>C | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2746576 | c.1023C>G | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
folC | 2746584 | c.1015T>C | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
folC | 2746594 | c.1005T>C | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
folC | 2746599 | p.Thr334Ala | missense_variant | 0.79 | para-aminosalicylic_acid | |
folC | 2746609 | c.990T>C | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
folC | 2746618 | c.981G>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
folC | 2746621 | c.978C>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
folC | 2746624 | c.975C>G | synonymous_variant | 0.84 | para-aminosalicylic_acid | |
folC | 2746631 | p.Gly323Val | missense_variant | 0.83 | para-aminosalicylic_acid | |
folC | 2746663 | c.936T>C | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
folC | 2746666 | c.933C>G | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
folC | 2746677 | p.Ser308Ala | missense_variant | 0.74 | para-aminosalicylic_acid | |
folC | 2746678 | c.921T>G | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
folC | 2746687 | c.912C>G | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2746693 | c.906G>C | synonymous_variant | 0.71 | para-aminosalicylic_acid | |
folC | 2746714 | c.885T>C | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2746728 | c.871T>C | synonymous_variant | 0.6 | para-aminosalicylic_acid | |
folC | 2746734 | p.Ile289Val | missense_variant | 0.61 | para-aminosalicylic_acid | |
folC | 2746741 | c.858C>T | synonymous_variant | 0.6 | para-aminosalicylic_acid | |
folC | 2747032 | c.567A>G | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747059 | c.540T>C | synonymous_variant | 0.77 | para-aminosalicylic_acid | |
folC | 2747065 | c.534C>G | synonymous_variant | 0.81 | para-aminosalicylic_acid | |
folC | 2747086 | c.513A>C | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2747089 | c.510G>C | synonymous_variant | 0.71 | para-aminosalicylic_acid | |
folC | 2747101 | c.498G>C | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
folC | 2747107 | c.492G>C | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747110 | c.489T>C | synonymous_variant | 0.63 | para-aminosalicylic_acid | |
folC | 2747113 | c.486C>G | synonymous_variant | 0.63 | para-aminosalicylic_acid | |
folC | 2747116 | c.483G>C | synonymous_variant | 0.63 | para-aminosalicylic_acid | |
folC | 2747134 | c.465C>G | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
folC | 2747224 | c.375G>C | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747239 | c.360T>C | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747242 | c.357G>A | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2747264 | p.Gly112Ser | missense_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747275 | c.324T>C | synonymous_variant | 0.63 | para-aminosalicylic_acid | |
folC | 2747287 | p.Pro104Ala | missense_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747290 | c.309A>G | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747293 | c.306G>A | synonymous_variant | 0.71 | para-aminosalicylic_acid | |
folC | 2747302 | c.297A>G | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
folC | 2747314 | c.285A>C | synonymous_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747317 | c.282C>G | synonymous_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747326 | c.273G>A | synonymous_variant | 0.65 | para-aminosalicylic_acid | |
folC | 2747334 | c.265C>T | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2747343 | p.Val86Ile | missense_variant | 0.7 | para-aminosalicylic_acid | |
folC | 2747355 | p.Val82Ile | missense_variant | 0.71 | para-aminosalicylic_acid | |
folC | 2747359 | c.240C>G | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
folC | 2747362 | c.237G>A | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
folC | 2747394 | p.Ile69Val | missense_variant | 0.74 | para-aminosalicylic_acid | |
folC | 2747407 | c.192T>C | synonymous_variant | 0.71 | para-aminosalicylic_acid | |
folC | 2747410 | c.187_188delAG | frameshift_variant | 0.74 | para-aminosalicylic_acid | |
folC | 2747414 | c.184_185insTG | frameshift_variant | 0.71 | para-aminosalicylic_acid | |
folC | 2747419 | c.180C>G | synonymous_variant | 0.74 | para-aminosalicylic_acid | |
folC | 2747442 | c.157T>C | synonymous_variant | 0.74 | para-aminosalicylic_acid | |
folC | 2747467 | p.Asp44Glu | missense_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747473 | p.Arg42Lys | missense_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747491 | c.108A>G | synonymous_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747497 | c.102C>G | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
folC | 2747500 | c.99A>G | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2747503 | c.96T>C | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
folC | 2747517 | c.82C>T | synonymous_variant | 0.7 | para-aminosalicylic_acid | |
folC | 2747521 | c.78C>G | synonymous_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747718 | c.-120G>A | upstream_gene_variant | 0.57 | para-aminosalicylic_acid | |
folC | 2747726 | c.-128G>A | upstream_gene_variant | 0.59 | para-aminosalicylic_acid | |
folC | 2747733 | c.-135G>A | upstream_gene_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747745 | c.-147A>C | upstream_gene_variant | 0.71 | para-aminosalicylic_acid | |
folC | 2747748 | c.-150C>G | upstream_gene_variant | 0.68 | para-aminosalicylic_acid | |
folC | 2747751 | c.-154_-153delGCinsCG | upstream_gene_variant | 0.65 | para-aminosalicylic_acid | |
folC | 2747759 | c.-161T>C | upstream_gene_variant | 0.65 | para-aminosalicylic_acid | |
folC | 2747760 | c.-162G>T | upstream_gene_variant | 0.65 | para-aminosalicylic_acid | |
folC | 2747772 | c.-174C>G | upstream_gene_variant | 0.73 | para-aminosalicylic_acid | |
folC | 2747781 | c.-183G>A | upstream_gene_variant | 0.76 | para-aminosalicylic_acid | |
folC | 2747790 | c.-192G>C | upstream_gene_variant | 0.76 | para-aminosalicylic_acid | |
Rv2477c | 2782393 | c.1650C>G | synonymous_variant | 0.6 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782396 | c.1647G>A | synonymous_variant | 0.57 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782399 | c.1644T>C | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782405 | c.1638A>G | synonymous_variant | 0.55 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782408 | c.1635T>A | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782411 | c.1632C>G | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782414 | p.Asp543Glu | missense_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782418 | p.Val542Ala | missense_variant | 0.59 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | ||||||
Rv2477c | 2782426 | c.1617G>T | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782432 | p.Val537Ile | missense_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782450 | c.1593C>G | synonymous_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782453 | c.1590C>T | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.66 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782510 | c.1533G>C | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782531 | c.1512C>G | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>G | synonymous_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782549 | c.1494T>C | synonymous_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782567 | c.1476C>G | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782612 | c.1431T>G | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782621 | c.1422T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782624 | c.1419G>C | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782633 | c.1410G>C | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782636 | c.1407G>C | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782639 | c.1404A>G | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782651 | c.1392T>C | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782654 | c.1389G>C | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782660 | c.1383C>A | synonymous_variant | 0.61 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782669 | c.1374A>G | synonymous_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782680 | c.1363T>C | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782684 | c.1359T>C | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782705 | c.1338G>A | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782708 | c.1335C>T | synonymous_variant | 0.63 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782714 | c.1329A>C | synonymous_variant | 0.62 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782720 | c.1323T>C | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782729 | c.1314A>G | synonymous_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782732 | c.1311A>G | synonymous_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782738 | c.1305C>T | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782750 | c.1293T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782753 | c.1290G>A | synonymous_variant | 0.56 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782759 | c.1284A>G | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782768 | c.1275C>T | synonymous_variant | 0.33 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 0.43 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.54 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782885 | c.1158G>C | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 0.78 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.81 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.81 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.83 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.83 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.82 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.8 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.8 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.79 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783020 | c.1023G>C | synonymous_variant | 0.78 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.78 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>C | synonymous_variant | 0.8 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.75 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783065 | c.978C>T | synonymous_variant | 0.72 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.73 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783087 | p.Asn319Ser | missense_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.67 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>C | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.66 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.71 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783182 | c.859_861delCGCinsAGG | synonymous_variant | 0.73 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783193 | p.Ser284Gly | missense_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.79 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.79 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.84 | kanamycin | |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.84 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783244 | p.Thr267Ala | missense_variant | 0.85 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.85 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.79 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783285 | p.Ala253Gly | missense_variant | 0.73 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783289 | p.Leu252Ile | missense_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.63 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783356 | c.687C>G | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.81 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.82 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 0.75 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783446 | c.597A>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.66 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.66 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.66 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>G | synonymous_variant | 0.68 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783499 | c.544T>C | synonymous_variant | 0.73 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.73 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.72 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783551 | c.492G>A | synonymous_variant | 0.68 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.68 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783566 | c.477C>T | synonymous_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.66 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.68 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783629 | c.414C>T | synonymous_variant | 0.68 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783641 | c.402G>C | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.73 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783695 | c.348C>T | synonymous_variant | 0.66 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783710 | c.333C>A | synonymous_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.73 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.77 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783770 | c.273G>A | synonymous_variant | 0.77 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.72 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783812 | c.231G>C | synonymous_variant | 0.74 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.63 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783836 | c.207C>G | synonymous_variant | 0.63 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783853 | c.190C>T | synonymous_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.68 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.79 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.79 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.77 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.83 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.84 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.85 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.85 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.86 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.85 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.81 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784016 | c.27G>A | synonymous_variant | 0.76 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
pepQ | 2859678 | c.741A>G | synonymous_variant | 0.45 | bedaquiline | |
clofazimine | ||||||
pepQ | 2859702 | c.715_717delTTGinsCTC | synonymous_variant | 0.43 | bedaquiline | |
clofazimine | ||||||
pepQ | 2859723 | c.696T>C | synonymous_variant | 0.45 | bedaquiline | |
clofazimine | Not assoc w R - Interim | |||||
pepQ | 2859735 | c.684G>C | synonymous_variant | 0.57 | bedaquiline | |
clofazimine | ||||||
pepQ | 2859739 | p.Ala227Gly | missense_variant | 0.6 | bedaquiline | |
clofazimine | ||||||
Rv2681 | 2996539 | c.-200T>C | upstream_gene_variant | 0.48 | capreomycin | |
Rv2681 | 2996560 | c.-179G>C | upstream_gene_variant | 0.48 | capreomycin | |
Rv2681 | 2996563 | c.-176A>C | upstream_gene_variant | 0.48 | capreomycin | |
Rv2681 | 2996569 | c.-170C>A | upstream_gene_variant | 0.5 | capreomycin | |
Rv2681 | 2996593 | c.-146T>C | upstream_gene_variant | 0.52 | capreomycin | |
Rv2681 | 2996602 | c.-137G>C | upstream_gene_variant | 0.52 | capreomycin | |
Rv2681 | 2996608 | c.-131A>G | upstream_gene_variant | 0.55 | capreomycin | |
Rv2681 | 2996611 | c.-128G>C | upstream_gene_variant | 0.55 | capreomycin | |
Rv2681 | 2996906 | c.168A>G | synonymous_variant | 0.68 | capreomycin | |
Rv2681 | 2996940 | p.Gly68Asn | missense_variant | 0.65 | capreomycin | |
Rv2681 | 2996945 | c.207C>G | synonymous_variant | 0.68 | capreomycin | |
Rv2681 | 2996957 | c.219T>C | synonymous_variant | 0.7 | capreomycin | |
Rv2681 | 2996966 | c.228G>A | synonymous_variant | 0.56 | capreomycin | |
Rv2681 | 2996974 | p.Glu79Gly | missense_variant | 0.5 | capreomycin | |
Rv2681 | 2996976 | p.Ala80Ser | missense_variant | 0.47 | capreomycin | |
Rv2681 | 2996987 | c.249A>G | synonymous_variant | 0.46 | capreomycin | |
Rv2752c | 3064773 | c.1419C>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064776 | c.1416T>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064779 | c.1413C>T | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064790 | c.1402T>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064797 | c.1395G>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064808 | c.1384C>T | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064830 | p.Ala454Gln | missense_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064838 | c.1354T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064860 | c.1332G>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065018 | p.Asn392His | missense_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065028 | p.Val388Ile | missense_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065040 | c.1152C>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065048 | c.1144C>T | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065052 | c.1140G>A | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065055 | c.1137T>G | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065085 | c.1105_1107delAGGinsCGC | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065109 | c.1081_1083delAGAinsCGC | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065126 | p.Ser356Ala | missense_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065127 | c.1065G>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065130 | p.Ala354Glu | missense_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065154 | c.1038G>A | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065163 | c.1029C>T | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065166 | c.1026C>G | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065183 | p.Ser337Ala | missense_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065451 | c.741G>A | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065466 | c.726G>T | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065481 | c.711T>C | synonymous_variant | 0.6 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065487 | c.705T>G | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065490 | c.702A>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065493 | c.699G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065496 | c.696G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065499 | c.693A>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065508 | c.684T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065511 | c.681G>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065517 | c.675C>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065520 | c.672G>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065532 | c.660A>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065553 | c.639A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065562 | c.630T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065595 | p.Leu199Phe | missense_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065607 | c.585C>G | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065612 | p.Thr194Ala | missense_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065622 | c.570G>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065625 | c.567G>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065634 | c.558G>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065637 | c.555A>G | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065640 | c.552T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065646 | c.546C>G | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065649 | c.543T>G | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065659 | p.Pro178Leu | missense_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3065661 | c.531A>G | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065666 | c.526T>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065667 | c.525A>G | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065675 | p.Phe173Leu | missense_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065715 | p.Tyr159His | missense_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065721 | c.471G>C | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065727 | c.465C>G | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065732 | c.460T>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065739 | c.453G>C | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065742 | p.Thr150Ile | missense_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065748 | c.444T>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065751 | c.441C>T | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065768 | p.Glu142Gln | missense_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065772 | c.420G>A | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065775 | c.417T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066054 | c.138T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066066 | c.126T>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066075 | c.117A>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066087 | c.105A>G | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3066118 | p.Asn25Ser | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066120 | c.72C>T | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066132 | c.60G>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066135 | c.57C>T | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066707 | c.-516A>G | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066713 | c.-522C>T | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066734 | c.-543G>A | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066741 | c.-550T>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066747 | c.-558_-556delCAAinsATC | upstream_gene_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066756 | c.-567_-565delCGGinsAGC | upstream_gene_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066771 | c.-580C>G | upstream_gene_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066774 | c.-583T>C | upstream_gene_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066780 | c.-589C>G | upstream_gene_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066783 | c.-592G>C | upstream_gene_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066807 | c.-616T>C | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066819 | c.-628T>C | upstream_gene_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066822 | c.-631T>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066834 | c.-643G>T | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066839 | c.-648A>G | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066846 | c.-655G>C | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067210 | c.736T>C | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067211 | c.735G>A | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067223 | c.723G>C | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067229 | c.717C>G | synonymous_variant | 0.65 | para-aminosalicylic_acid | |
thyX | 3067249 | p.Thr233Ser | missense_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067250 | p.Val232Ile | missense_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067273 | p.Ala225Thr | missense_variant | 0.89 | para-aminosalicylic_acid | |
thyX | 3067277 | c.669C>G | synonymous_variant | 0.87 | para-aminosalicylic_acid | |
thyX | 3067284 | p.Ala221Gly | missense_variant | 0.87 | para-aminosalicylic_acid | |
thyX | 3067286 | c.660C>G | synonymous_variant | 0.87 | para-aminosalicylic_acid | |
thyX | 3067289 | c.657C>G | synonymous_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067304 | c.642A>G | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
thyX | 3067313 | c.633G>C | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
thyX | 3067316 | c.630A>G | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.78 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.84 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.84 | para-aminosalicylic_acid | |
thyX | 3067412 | c.534C>G | synonymous_variant | 0.78 | para-aminosalicylic_acid | |
thyX | 3067424 | c.522G>A | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyX | 3067427 | c.519G>C | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.78 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
thyX | 3067634 | c.312C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067643 | c.303C>T | synonymous_variant | 0.42 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.48 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067676 | c.270C>A | synonymous_variant | 0.61 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.61 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.61 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.59 | para-aminosalicylic_acid | |
thyX | 3067724 | c.222G>A | synonymous_variant | 0.63 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.63 | para-aminosalicylic_acid | |
thyX | 3067736 | c.210C>T | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067742 | c.204A>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.59 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.57 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 0.85 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.89 | para-aminosalicylic_acid | |
thyX | 3067796 | c.150C>G | synonymous_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
thyX | 3067811 | c.135G>A | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
thyX | 3067826 | c.120C>T | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.89 | para-aminosalicylic_acid | |
thyX | 3067856 | p.Asp30Glu | missense_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.89 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.85 | para-aminosalicylic_acid | |
thyX | 3067883 | c.63C>G | synonymous_variant | 0.81 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067889 | c.57C>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067935 | p.Thr4Ile | missense_variant | 0.47 | para-aminosalicylic_acid | |
thyA | 3073860 | c.612C>G | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
thyA | 3073863 | c.609T>C | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
thyA | 3073866 | c.606C>G | synonymous_variant | 0.63 | para-aminosalicylic_acid | |
thyA | 3073872 | p.Ile200Val | missense_variant | 0.69 | para-aminosalicylic_acid | |
thyA | 3073889 | p.Ser195Ala | missense_variant | 0.75 | para-aminosalicylic_acid | |
thyA | 3073890 | c.580_582delTTGinsCTC | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 0.81 | para-aminosalicylic_acid | |
thyA | 3073917 | c.555C>G | synonymous_variant | 0.84 | para-aminosalicylic_acid | |
thyA | 3073920 | c.552C>G | synonymous_variant | 0.84 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.86 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
thyA | 3073971 | c.501C>T | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.77 | para-aminosalicylic_acid | |
thyA | 3074001 | c.471C>G | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>G | synonymous_variant | 0.77 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
thyA | 3074045 | c.427C>T | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
thyA | 3074056 | p.Glu139Pro | missense_variant | 0.8 | para-aminosalicylic_acid | |
thyA | 3074097 | c.375C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyA | 3074100 | c.372T>C | synonymous_variant | 0.55 | para-aminosalicylic_acid | |
thyA | 3074106 | c.366T>C | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyA | 3074372 | p.Met34Leu | missense_variant | 0.45 | para-aminosalicylic_acid | |
thyA | 3074379 | c.93C>T | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612621 | c.496T>C | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
Rv3236c | 3612622 | c.495C>T | synonymous_variant | 0.42 | pyrazinamide | |
Rv3236c | 3612628 | c.489G>C | synonymous_variant | 0.48 | pyrazinamide | |
Rv3236c | 3612667 | c.450T>G | synonymous_variant | 0.58 | pyrazinamide | |
Rv3236c | 3612676 | c.441A>G | synonymous_variant | 0.59 | pyrazinamide | |
Rv3236c | 3612694 | p.Arg141Gln | missense_variant | 0.67 | pyrazinamide | |
Rv3236c | 3612708 | c.409T>C | synonymous_variant | 0.6 | pyrazinamide | |
Rv3236c | 3612721 | c.396G>C | synonymous_variant | 0.55 | pyrazinamide | |
Rv3236c | 3612724 | c.393T>C | synonymous_variant | 0.47 | pyrazinamide | |
Rv3236c | 3612736 | c.381T>C | synonymous_variant | 0.44 | pyrazinamide | |
lpqB | 3623356 | p.Leu519Ile | missense_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623360 | c.1551A>G | synonymous_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623363 | c.1548T>C | synonymous_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623366 | c.1545T>C | synonymous_variant | 0.38 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623378 | p.Ala511Gly | missense_variant | 0.38 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623393 | c.1518A>C | synonymous_variant | 0.54 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623417 | c.1494A>C | synonymous_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623423 | c.1488C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3623428 | c.1483T>C | synonymous_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623449 | c.1462C>T | synonymous_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623459 | c.1452G>C | synonymous_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623465 | c.1446G>C | synonymous_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623468 | c.1443T>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3623472 | p.Tyr480Phe | missense_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623484 | p.Phe476Tyr | missense_variant | 0.59 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623489 | c.1422C>G | synonymous_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623492 | c.1419T>C | synonymous_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623512 | p.Gly467Ser | missense_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623516 | c.1395C>G | synonymous_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623519 | c.1392C>T | synonymous_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623528 | c.1383G>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3623531 | c.1380T>C | synonymous_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623552 | c.1359G>C | synonymous_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623555 | p.Gly452Ser | missense_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623561 | c.1350T>C | synonymous_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623570 | c.1341A>G | synonymous_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623573 | c.1338T>G | synonymous_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623576 | c.1335T>C | synonymous_variant | 0.4 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623580 | p.Asn444Thr | missense_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623587 | p.Ala442Pro | missense_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624062 | p.Asn283Ser | missense_variant | 0.41 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624077 | c.834G>C | synonymous_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624082 | c.829A>C | synonymous_variant | 0.66 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624100 | c.811T>C | synonymous_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624107 | c.804C>T | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624116 | c.795A>G | synonymous_variant | 0.77 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624119 | c.792C>G | synonymous_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624125 | c.786A>G | synonymous_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624133 | c.778A>C | synonymous_variant | 0.83 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624157 | c.754C>T | synonymous_variant | 0.89 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624166 | p.Met249Leu | missense_variant | 0.88 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624173 | c.738A>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624179 | c.732C>G | synonymous_variant | 0.82 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624182 | c.729C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624188 | c.723G>A | synonymous_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624194 | c.717C>G | synonymous_variant | 0.74 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624200 | c.711A>C | synonymous_variant | 0.7 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624209 | c.702A>C | synonymous_variant | 0.66 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624224 | c.687T>C | synonymous_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624323 | c.588G>C | synonymous_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624331 | c.580C>T | synonymous_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624339 | p.Arg191His | missense_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624346 | p.Ser189Pro | missense_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624359 | c.552C>T | synonymous_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624365 | c.546T>C | synonymous_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624389 | c.522C>G | synonymous_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624392 | c.519C>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624407 | c.504C>G | synonymous_variant | 0.61 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624680 | c.231T>G | synonymous_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624686 | p.Glu75Gln | missense_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624701 | c.210T>C | synonymous_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624704 | c.207G>C | synonymous_variant | 0.55 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624707 | c.204G>C | synonymous_variant | 0.55 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624725 | c.186G>C | synonymous_variant | 0.55 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624745 | p.Leu56Phe | missense_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624749 | c.162G>A | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624755 | c.154_156delTTAinsCTG | synonymous_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3625099 | c.-189C>G | upstream_gene_variant | 0.46 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.46 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.38 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625149 | p.Val489Ile | missense_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625156 | c.-246G>C | upstream_gene_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.55 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 0.9 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625246 | c.-336G>A | upstream_gene_variant | 0.89 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625255 | c.-345T>C | upstream_gene_variant | 0.88 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625258 | c.-348G>C | upstream_gene_variant | 0.88 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625267 | c.1347T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 0.89 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625291 | c.-381A>G | upstream_gene_variant | 0.88 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625313 | p.Arg434Lys | missense_variant | 0.8 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625321 | c.1293A>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625327 | c.-417A>G | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625351 | c.1263T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625357 | c.-447T>C | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625497 | c.1117T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625510 | c.-600T>C | upstream_gene_variant | 0.66 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 0.63 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 0.66 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625549 | c.-639G>A | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625592 | p.Ser341Asn | missense_variant | 0.71 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625630 | c.-720C>G | upstream_gene_variant | 0.74 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.77 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625683 | c.-773C>T | upstream_gene_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.79 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.81 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.87 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625732 | c.882C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.8 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.83 | rifampicin | Uncertain significance |
bedaquiline | ||||||
lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.79 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.75 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
lpqB | 3625798 | c.-888G>C | upstream_gene_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 0.85 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625855 | c.759G>A | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.88 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625876 | c.738G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625888 | c.-978G>T | upstream_gene_variant | 0.87 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625927 | c.687T>C | synonymous_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625930 | c.684C>G | synonymous_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625936 | c.678C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625942 | c.672C>G | synonymous_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625945 | c.669A>G | synonymous_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625951 | c.663A>G | synonymous_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625955 | p.Leu220Ala | missense_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626092 | c.522T>G | synonymous_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626095 | p.Glu173Asp | missense_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626101 | p.Gln171His | missense_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626107 | p.Thr169Ser | missense_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626134 | c.480C>G | synonymous_variant | 0.54 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626157 | p.Ala153Ser | missense_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626158 | p.Asn152Ser | missense_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626170 | c.444T>C | synonymous_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626179 | c.435A>G | synonymous_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626185 | c.429T>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626188 | p.Ser142Thr | missense_variant | 0.4 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626191 | c.423C>G | synonymous_variant | 0.4 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626194 | c.420T>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3626203 | c.411G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626206 | c.408T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3626209 | c.405T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3626223 | c.391C>T | synonymous_variant | 0.39 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626284 | c.330T>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3626296 | c.318T>G | synonymous_variant | 0.59 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626308 | c.306T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626316 | c.298C>T | synonymous_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626317 | c.297A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626325 | p.Thr97Ala | missense_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626329 | c.285G>A | synonymous_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626332 | c.282T>C | synonymous_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626349 | p.Ser89Gly | missense_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626350 | c.264C>G | synonymous_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626377 | p.Asp79Glu | missense_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626383 | c.231G>C | synonymous_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626386 | c.228G>C | synonymous_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626390 | p.Arg75Lys | missense_variant | 0.56 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626400 | p.Ile72Val | missense_variant | 0.55 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626404 | c.210C>G | synonymous_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626407 | c.207C>G | synonymous_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626410 | c.204T>C | synonymous_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626684 | c.-71G>T | upstream_gene_variant | 0.83 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626708 | c.642G>A | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626720 | c.-107G>A | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626735 | c.-122C>T | upstream_gene_variant | 0.74 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626744 | c.-131G>C | upstream_gene_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.66 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.71 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.71 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626869 | c.481C>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.74 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.7 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626891 | c.-278G>C | upstream_gene_variant | 0.7 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626894 | c.-281C>T | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.71 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.77 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.82 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.73 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626981 | c.-368C>T | upstream_gene_variant | 0.81 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.84 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627023 | c.-410C>G | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627056 | c.294C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.77 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.79 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 0.79 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627149 | c.-536G>C | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
fbiA | 3640291 | c.-252T>C | upstream_gene_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiA | 3640302 | c.-241_-236delTTAACCinsA | upstream_gene_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiA | 3640347 | c.-196A>G | upstream_gene_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiA | 3640349 | c.-194A>G | upstream_gene_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiA | 3640350 | c.-193C>T | upstream_gene_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiA | 3640365 | c.-178C>G | upstream_gene_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642560 | c.1026T>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642566 | c.1032A>G | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642578 | c.1044C>G | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642581 | c.1047A>C | synonymous_variant | 0.68 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642587 | p.Met351Ile | missense_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642602 | c.1068A>C | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642605 | c.1071A>C | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642609 | c.1075_1076delAGinsTC | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642614 | c.1080C>T | synonymous_variant | 0.74 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642620 | c.1086T>C | synonymous_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642656 | c.1122G>C | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642662 | c.1128C>G | synonymous_variant | 0.66 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642668 | c.1134A>C | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642677 | c.1143A>G | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642680 | c.1146A>G | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642684 | c.1150T>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642701 | c.1167C>G | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642719 | c.1185T>C | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642743 | c.1209T>C | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642749 | c.1215T>C | synonymous_variant | 0.87 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642758 | c.1224C>G | synonymous_variant | 0.94 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642763 | p.Asp410Ala | missense_variant | 0.94 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642770 | c.1236G>C | synonymous_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642773 | p.Asp413Glu | missense_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642777 | p.Pro415Ala | missense_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642781 | p.Val416Ala | missense_variant | 0.72 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642809 | c.1275G>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642815 | c.1281A>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
alr | 3840215 | c.1206T>C | synonymous_variant | 0.62 | cycloserine | |
alr | 3840230 | c.1191T>G | synonymous_variant | 0.67 | cycloserine | |
alr | 3840233 | c.1188A>G | synonymous_variant | 0.67 | cycloserine | |
alr | 3840236 | c.1185A>C | synonymous_variant | 0.67 | cycloserine | |
alr | 3840239 | c.1182G>C | synonymous_variant | 0.7 | cycloserine | |
alr | 3840248 | c.1173C>G | synonymous_variant | 0.76 | cycloserine | |
alr | 3840274 | p.Val383Leu | missense_variant | 0.67 | cycloserine | |
alr | 3840275 | c.1146T>G | synonymous_variant | 0.67 | cycloserine | |
alr | 3840293 | c.1128T>G | synonymous_variant | 0.59 | cycloserine | |
alr | 3840296 | c.1125G>C | synonymous_variant | 0.56 | cycloserine | |
alr | 3840407 | c.1014G>C | synonymous_variant | 0.56 | cycloserine | |
alr | 3840410 | c.1011T>C | synonymous_variant | 0.59 | cycloserine | |
alr | 3840416 | p.Cys335Arg | missense_variant | 0.59 | cycloserine | |
alr | 3840419 | c.1002A>G | synonymous_variant | 0.59 | cycloserine | |
alr | 3840422 | c.999A>G | synonymous_variant | 0.62 | cycloserine | |
alr | 3840436 | c.985C>T | synonymous_variant | 0.71 | cycloserine | |
alr | 3840449 | c.972G>C | synonymous_variant | 0.67 | cycloserine | |
alr | 3840467 | c.954G>C | synonymous_variant | 0.57 | cycloserine | |
alr | 3840476 | c.945A>C | synonymous_variant | 0.5 | cycloserine | |
rpoA | 3877494 | p.Glu338Asp | missense_variant | 0.57 | rifampicin | Uncertain significance |
rpoA | 3877503 | p.Ala335Ser | missense_variant | 0.57 | rifampicin | |
rpoA | 3877506 | p.Gly334Ala | missense_variant | 0.57 | rifampicin | |
rpoA | 3877513 | p.Thr332Asn | missense_variant | 0.59 | rifampicin | |
rpoA | 3877515 | c.993G>C | synonymous_variant | 0.61 | rifampicin | |
rpoA | 3877542 | c.966C>T | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.71 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoA | 3877590 | c.918G>T | synonymous_variant | 0.77 | rifampicin | |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.8 | rifampicin | |
rpoA | 3877638 | c.870T>G | synonymous_variant | 0.83 | rifampicin | |
rpoA | 3877656 | c.852T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.76 | rifampicin | |
rpoA | 3877677 | p.Ala277Ser | missense_variant | 0.73 | rifampicin | |
rpoA | 3877680 | c.828G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoA | 3877710 | c.798C>T | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.72 | rifampicin | |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.86 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.8 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.82 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.87 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.84 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.81 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.76 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.73 | rifampicin | |
rpoA | 3878025 | c.483C>T | synonymous_variant | 0.71 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878046 | c.462T>C | synonymous_variant | 0.76 | rifampicin | |
rpoA | 3878049 | c.459G>C | synonymous_variant | 0.76 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.63 | rifampicin | |
rpoA | 3878073 | c.435C>T | synonymous_variant | 0.61 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.61 | rifampicin | |
rpoA | 3878082 | c.426T>C | synonymous_variant | 0.61 | rifampicin | |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.63 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.66 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.71 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.72 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>A | synonymous_variant | 0.81 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoA | 3878184 | c.324C>G | synonymous_variant | 0.93 | rifampicin | |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.93 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoA | 3878276 | c.232C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.91 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>T | synonymous_variant | 0.82 | rifampicin | |
rpoA | 3878307 | c.201C>G | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoA | 3878325 | c.183C>T | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.59 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.63 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.55 | rifampicin | |
rpoA | 3878370 | c.138T>C | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.73 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.68 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.69 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878396 | c.112C>T | synonymous_variant | 0.71 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.8 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.85 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.85 | rifampicin | |
rpoA | 3878454 | c.54A>G | synonymous_variant | 0.82 | rifampicin | |
rpoA | 3878459 | p.Asn17Asp | missense_variant | 0.82 | rifampicin | |
rpoA | 3878465 | p.Thr15Ser | missense_variant | 0.82 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.76 | rifampicin | |
rpoA | 3878475 | c.33G>A | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878478 | c.30C>G | synonymous_variant | 0.73 | rifampicin | |
rpoA | 3878701 | c.-194C>G | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3878713 | c.-206G>A | upstream_gene_variant | 0.58 | rifampicin | Uncertain significance |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.58 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.58 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.58 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.58 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.59 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.59 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.52 | rifampicin | |
rpoA | 3878769 | c.-262C>A | upstream_gene_variant | 0.52 | rifampicin | |
rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 0.62 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.65 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.74 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsGGC | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.85 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.83 | rifampicin | Uncertain significance |
rpoA | 3878893 | c.-386C>T | upstream_gene_variant | 0.88 | rifampicin | |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.89 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.85 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.83 | rifampicin | Uncertain significance |
rpoA | 3878935 | c.-428C>T | upstream_gene_variant | 0.83 | rifampicin | |
rpoA | 3878938 | c.-431T>G | upstream_gene_variant | 0.83 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.87 | rifampicin | Uncertain significance |
rpoA | 3878956 | c.-449G>C | upstream_gene_variant | 0.89 | rifampicin | |
rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.9 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>G | upstream_gene_variant | 0.88 | rifampicin | |
rpoA | 3878974 | c.-469_-467delATCinsGTG | upstream_gene_variant | 0.87 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.78 | rifampicin | Uncertain significance |
rpoA | 3879001 | c.-494C>T | upstream_gene_variant | 0.76 | rifampicin | |
rpoA | 3879004 | c.-499_-497delAAGinsCGC | upstream_gene_variant | 0.76 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.79 | rifampicin | |
rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 0.79 | rifampicin | |
rpoA | 3879033 | c.-526C>T | upstream_gene_variant | 0.75 | rifampicin | |
rpoA | 3879034 | c.-527G>A | upstream_gene_variant | 0.75 | rifampicin | |
rpoA | 3879040 | c.-535_-533delGTGinsTCC | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3879050 | c.-543A>C | upstream_gene_variant | 0.75 | rifampicin | |
rpoA | 3879061 | c.-554C>T | upstream_gene_variant | 0.68 | rifampicin | |
rpoA | 3879073 | c.-566A>G | upstream_gene_variant | 0.75 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.76 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.86 | rifampicin | |
rpoA | 3879117 | c.-610C>T | upstream_gene_variant | 0.85 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.87 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.89 | rifampicin | |
rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 0.89 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.91 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.91 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.9 | rifampicin | |
rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.73 | rifampicin | |
rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.72 | rifampicin | |
rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.69 | rifampicin | |
rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 0.69 | rifampicin | |
ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.91 | pretomanid | |
delamanid | ||||||
ddn | 3986648 | c.-196C>G | upstream_gene_variant | 0.85 | pretomanid | |
delamanid | ||||||
ddn | 3986651 | c.-193G>A | upstream_gene_variant | 0.85 | pretomanid | |
delamanid | ||||||
ddn | 3986660 | c.-184C>T | upstream_gene_variant | 0.79 | pretomanid | |
delamanid | ||||||
ddn | 3986665 | c.-179G>C | upstream_gene_variant | 0.79 | pretomanid | |
delamanid | ||||||
ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 0.78 | pretomanid | |
delamanid | ||||||
ddn | 3986690 | c.-154C>G | upstream_gene_variant | 0.74 | pretomanid | |
delamanid | ||||||
ddn | 3986696 | c.-148G>C | upstream_gene_variant | 0.72 | pretomanid | |
delamanid | ||||||
ddn | 3986705 | c.-139C>G | upstream_gene_variant | 0.65 | pretomanid | |
delamanid | ||||||
clpC1 | 4038308 | c.2397G>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4038314 | c.2391T>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4038320 | c.2385G>C | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038325 | p.Val794Ile | missense_variant | 0.67 | pyrazinamide | |
clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.74 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.74 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.72 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.71 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038425 | c.2280C>G | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4038519 | p.Arg729Gln | missense_variant | 0.64 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.74 | pyrazinamide | |
clpC1 | 4038541 | c.2164C>T | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.87 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.74 | pyrazinamide | |
clpC1 | 4038644 | p.Glu687Asp | missense_variant | 0.72 | pyrazinamide | |
clpC1 | 4038647 | c.2058T>C | synonymous_variant | 0.74 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.66 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.64 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4038674 | c.2031C>G | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.66 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038692 | c.2013C>G | synonymous_variant | 0.67 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.72 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.83 | pyrazinamide | |
clpC1 | 4038917 | c.1788C>T | synonymous_variant | 0.83 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.83 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.82 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.78 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.87 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.89 | pyrazinamide | |
clpC1 | 4039040 | c.1665C>G | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4039094 | c.1611C>G | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4039124 | c.1581C>T | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039136 | c.1569C>T | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039139 | p.Glu522Val | missense_variant | 0.67 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.7 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4039187 | c.1518G>T | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4039258 | p.Gln483Glu | missense_variant | 0.56 | pyrazinamide | |
clpC1 | 4039259 | p.Glu482Asn | missense_variant | 0.55 | pyrazinamide | |
clpC1 | 4039268 | c.1437C>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.51 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039280 | c.1425G>T | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | p.Leu473Met | missense_variant | 0.58 | pyrazinamide | |
clpC1 | 4039289 | c.1416T>C | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039313 | c.1392C>T | synonymous_variant | 0.66 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.7 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>G | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>G | synonymous_variant | 0.66 | pyrazinamide | |
clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.62 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039361 | c.1344C>G | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4039382 | c.1323C>T | synonymous_variant | 0.84 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.82 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.84 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4039439 | c.1266C>T | synonymous_variant | 0.82 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.82 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>G | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4039568 | p.Met379Ile | missense_variant | 0.92 | pyrazinamide | Uncertain significance |
clpC1 | 4039574 | p.Ala377Ser | missense_variant | 0.91 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039581 | p.Thr375Ser | missense_variant | 0.9 | pyrazinamide | |
clpC1 | 4039601 | c.1104G>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4039621 | c.1084C>T | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>A | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4039646 | p.Glu353Ala | missense_variant | 0.77 | pyrazinamide | |
clpC1 | 4039715 | c.990G>A | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.72 | pyrazinamide | |
clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039814 | c.891C>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.63 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.72 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039940 | c.765G>A | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.84 | pyrazinamide | |
clpC1 | 4039991 | c.714G>T | synonymous_variant | 0.83 | pyrazinamide | |
clpC1 | 4039996 | p.Glu237Gln | missense_variant | 0.79 | pyrazinamide | |
clpC1 | 4040009 | c.696C>G | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4040015 | c.690G>A | synonymous_variant | 0.77 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.79 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4040030 | c.675C>G | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4040042 | c.663C>T | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040048 | c.657C>T | synonymous_variant | 0.82 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4040093 | c.610_612delCTCinsTTG | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.72 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040153 | c.552A>G | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.68 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.66 | pyrazinamide | |
clpC1 | 4040200 | c.505T>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040207 | c.498T>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040222 | c.483G>A | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040228 | c.477G>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4040252 | c.453C>G | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.59 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040276 | c.427_429delTCCinsAGT | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040284 | c.421C>T | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4040315 | c.390G>A | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4040348 | c.357G>T | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4040363 | c.342A>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4040393 | c.312G>T | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4040411 | c.294T>A | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.73 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040462 | c.243C>G | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4040468 | c.237G>C | synonymous_variant | 0.84 | pyrazinamide | |
clpC1 | 4040477 | c.228G>A | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4040486 | c.219G>C | synonymous_variant | 0.9 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.85 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040528 | c.177G>T | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.78 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040537 | c.168G>T | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4040567 | c.138C>G | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040570 | c.135C>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4040573 | c.132T>C | synonymous_variant | 0.64 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4040654 | c.51G>A | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4040657 | c.48T>G | synonymous_variant | 0.64 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040674 | c.31A>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040675 | c.30C>G | synonymous_variant | 0.64 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040678 | c.27C>A | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040681 | c.24T>A | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040690 | c.15T>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040695 | c.10C>A | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040699 | c.6C>T | synonymous_variant | 0.6 | pyrazinamide | |
panD | 4044072 | c.210C>A | synonymous_variant | 0.29 | pyrazinamide | |
panD | 4044075 | c.207T>C | synonymous_variant | 0.33 | pyrazinamide | |
panD | 4044084 | c.198T>C | synonymous_variant | 0.46 | pyrazinamide | |
panD | 4044093 | c.189A>G | synonymous_variant | 0.53 | pyrazinamide | |
panD | 4044120 | c.162A>G | synonymous_variant | 0.61 | pyrazinamide | |
panD | 4044123 | c.159T>C | synonymous_variant | 0.63 | pyrazinamide | |
panD | 4044126 | c.156T>C | synonymous_variant | 0.65 | pyrazinamide | |
panD | 4044138 | c.144T>C | synonymous_variant | 0.66 | pyrazinamide | Not assoc w R - Interim |
panD | 4044150 | c.132A>C | synonymous_variant | 0.69 | pyrazinamide | |
panD | 4044162 | c.120A>G | synonymous_variant | 0.68 | pyrazinamide | |
panD | 4044165 | c.117G>C | synonymous_variant | 0.71 | pyrazinamide | |
panD | 4044174 | c.108C>G | synonymous_variant | 0.71 | pyrazinamide | |
panD | 4044180 | c.102C>T | synonymous_variant | 0.7 | pyrazinamide | |
panD | 4044188 | c.94T>C | synonymous_variant | 0.58 | pyrazinamide | |
panD | 4044189 | c.93C>T | synonymous_variant | 0.61 | pyrazinamide | |
panD | 4044195 | c.87T>C | synonymous_variant | 0.6 | pyrazinamide | |
panD | 4044231 | p.Cys17Gln | missense_variant | 0.7 | pyrazinamide | |
panD | 4044237 | c.45G>C | synonymous_variant | 0.67 | pyrazinamide | |
panD | 4044240 | c.42G>C | synonymous_variant | 0.68 | pyrazinamide | |
panD | 4044989 | c.-708T>C | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4044995 | c.-714A>G | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4045000 | c.-719A>C | upstream_gene_variant | 0.58 | pyrazinamide | |
panD | 4045022 | c.-741C>G | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4045025 | c.-744C>G | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4045028 | c.-747C>G | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4045033 | c.-752T>G | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4045034 | c.-753A>C | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4045055 | c.-774T>C | upstream_gene_variant | 0.63 | pyrazinamide | |
panD | 4045063 | c.-782T>C | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4045067 | c.-786C>G | upstream_gene_variant | 0.55 | pyrazinamide | |
panD | 4045076 | c.-795A>C | upstream_gene_variant | 0.55 | pyrazinamide | |
panD | 4045085 | c.-804G>A | upstream_gene_variant | 0.47 | pyrazinamide | |
panD | 4045088 | c.-807T>C | upstream_gene_variant | 0.44 | pyrazinamide | |
panD | 4045094 | c.-813T>C | upstream_gene_variant | 0.43 | pyrazinamide | |
panD | 4045097 | c.-816T>C | upstream_gene_variant | 0.4 | pyrazinamide | |
glpK | 4138511 | c.1245C>T | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138514 | c.1242A>G | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138518 | p.Glu413Ala | missense_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138523 | c.1233C>A | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138535 | c.1221T>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138541 | c.1215C>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138547 | c.1209C>T | synonymous_variant | 0.69 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138568 | c.1188A>G | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138571 | c.1185C>T | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138580 | c.1176C>T | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138601 | c.1155G>C | synonymous_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138606 | c.1150T>C | synonymous_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138607 | c.1149G>C | synonymous_variant | 0.84 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138634 | c.1122G>A | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138643 | c.1113A>C | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138654 | c.1102C>T | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138658 | c.1098C>G | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138667 | c.1089G>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138670 | c.1086G>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138679 | p.Met359Val | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138682 | c.1074C>A | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138697 | c.1059C>G | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138706 | c.1050C>A | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138714 | p.Ala348Ser | missense_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138715 | c.1041G>A | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138774 | p.Ser328Ala | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138796 | c.960A>G | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139126 | c.630G>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139132 | c.624A>G | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139135 | p.Asp207Asn | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139143 | c.613T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139165 | c.591A>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139168 | c.588T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139175 | p.Val194Ala | missense_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139177 | c.579T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139183 | c.573T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139186 | c.570G>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139189 | c.567G>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139195 | c.561G>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139198 | c.558C>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139207 | c.549T>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139228 | p.Pro176Ala | missense_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139231 | c.525A>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139242 | c.514T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139243 | c.513A>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139249 | c.507C>T | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139255 | c.501G>A | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139270 | c.486C>G | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139273 | c.483A>G | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139276 | c.480T>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139282 | c.474T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139285 | p.Glu157Asp | missense_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139297 | c.459G>A | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139581 | p.Asn59Asp | missense_variant | 0.62 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
glpK | 4139615 | c.141G>A | synonymous_variant | 0.74 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
glpK | 4139627 | c.129G>A | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139630 | c.126C>T | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139636 | c.120C>A | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139642 | c.114G>A | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139648 | c.108T>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139651 | p.His35Glu | missense_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139675 | c.81C>T | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139687 | c.69C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4240019 | p.Asn53Asp | missense_variant | 0.53 | ethambutol | |
embC | 4240033 | c.171G>C | synonymous_variant | 0.53 | ethambutol | |
embC | 4240037 | c.175_177delTTGinsCTC | synonymous_variant | 0.5 | ethambutol | |
embC | 4240048 | c.186C>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4240051 | c.189A>G | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embC | 4240060 | c.198G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4240065 | p.Ala68Gly | missense_variant | 0.5 | ethambutol | |
embC | 4240069 | c.207T>C | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embC | 4240075 | p.Glu71Asp | missense_variant | 0.52 | ethambutol | |
embC | 4240078 | c.216A>G | synonymous_variant | 0.52 | ethambutol | |
embC | 4240087 | c.225T>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4240096 | c.234G>C | synonymous_variant | 0.48 | ethambutol | |
embC | 4240110 | p.Asn83Thr | missense_variant | 0.39 | ethambutol | |
embC | 4240123 | c.261C>G | synonymous_variant | 0.32 | ethambutol | |
embC | 4240127 | p.Gln89Glu | missense_variant | 0.33 | ethambutol | |
embC | 4240475 | p.Ala205Ser | missense_variant | 0.5 | ethambutol | Uncertain significance |
embC | 4240480 | c.618G>A | synonymous_variant | 0.5 | ethambutol | |
embC | 4240489 | c.627A>G | synonymous_variant | 0.47 | ethambutol | |
embC | 4240490 | p.Pro210Ser | missense_variant | 0.47 | ethambutol | Uncertain significance |
embC | 4240495 | c.633T>C | synonymous_variant | 0.45 | ethambutol | |
embC | 4240500 | p.Ser213Asn | missense_variant | 0.5 | ethambutol | Uncertain significance |
embC | 4240512 | p.Ser217Asn | missense_variant | 0.56 | ethambutol | |
embC | 4240514 | p.Val218Ile | missense_variant | 0.56 | ethambutol | |
embC | 4240519 | c.657T>C | synonymous_variant | 0.6 | ethambutol | |
embC | 4240543 | c.681G>C | synonymous_variant | 0.59 | ethambutol | |
embC | 4240561 | c.699C>G | synonymous_variant | 0.55 | ethambutol | |
embC | 4240574 | p.Val238Leu | missense_variant | 0.61 | ethambutol | |
embC | 4240578 | p.Ala239Val | missense_variant | 0.61 | ethambutol | |
embC | 4240585 | c.723C>G | synonymous_variant | 0.61 | ethambutol | |
embC | 4240587 | p.Gly242Ala | missense_variant | 0.65 | ethambutol | |
embC | 4240642 | c.780G>C | synonymous_variant | 0.79 | ethambutol | |
embC | 4240645 | c.783G>C | synonymous_variant | 0.83 | ethambutol | |
embC | 4240657 | c.795G>C | synonymous_variant | 0.83 | ethambutol | |
embC | 4240671 | p.Thr270Ile | missense_variant | 0.85 | ethambutol | Not assoc w R |
embC | 4240678 | c.816T>G | synonymous_variant | 0.84 | ethambutol | |
embC | 4240685 | p.Thr275Ala | missense_variant | 0.84 | ethambutol | |
embC | 4240693 | c.831T>G | synonymous_variant | 0.81 | ethambutol | |
embC | 4240698 | p.Ala279Gly | missense_variant | 0.82 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 0.87 | ethambutol | Not assoc w R - Interim |
embC | 4240738 | c.876C>A | synonymous_variant | 0.9 | ethambutol | |
embC | 4240765 | c.903C>G | synonymous_variant | 0.79 | ethambutol | |
embC | 4240780 | c.918T>C | synonymous_variant | 0.81 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.79 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.77 | ethambutol | |
embC | 4240807 | c.945C>G | synonymous_variant | 0.74 | ethambutol | Not assoc w R - Interim |
embC | 4240811 | p.Phe317Leu | missense_variant | 0.71 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.66 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.63 | ethambutol | |
embC | 4240849 | c.987C>T | synonymous_variant | 0.56 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.65 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 0.65 | ethambutol | |
embC | 4240873 | c.1011C>G | synonymous_variant | 0.65 | ethambutol | |
embC | 4240879 | c.1017G>C | synonymous_variant | 0.63 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 0.63 | ethambutol | Uncertain significance |
embC | 4240885 | c.1023T>C | synonymous_variant | 0.63 | ethambutol | |
embC | 4240886 | p.Ile342Val | missense_variant | 0.61 | ethambutol | |
embC | 4240897 | c.1035C>G | synonymous_variant | 0.59 | ethambutol | Not assoc w R |
embC | 4240898 | c.1036_1038delCTAinsTTG | synonymous_variant | 0.59 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4240924 | c.1062C>G | synonymous_variant | 0.48 | ethambutol | |
embC | 4240936 | c.1074A>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4240948 | c.1086G>A | synonymous_variant | 0.56 | ethambutol | Not assoc w R - Interim |
embC | 4240954 | p.Ile364Met | missense_variant | 0.54 | ethambutol | |
embC | 4240966 | c.1104G>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4240969 | c.1107C>T | synonymous_variant | 0.52 | ethambutol | Not assoc w R - Interim |
embC | 4240978 | c.1116G>A | synonymous_variant | 0.52 | ethambutol | Not assoc w R - Interim |
embC | 4240979 | p.Thr373Gln | missense_variant | 0.54 | ethambutol | |
embC | 4240983 | p.Ser374Asn | missense_variant | 0.57 | ethambutol | |
embC | 4240990 | c.1128A>C | synonymous_variant | 0.66 | ethambutol | |
embC | 4240996 | c.1134G>C | synonymous_variant | 0.68 | ethambutol | |
embC | 4241002 | c.1140G>A | synonymous_variant | 0.7 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 0.75 | ethambutol | |
embC | 4241023 | c.1161T>C | synonymous_variant | 0.74 | ethambutol | |
embC | 4241047 | c.1185C>G | synonymous_variant | 0.78 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.76 | ethambutol | |
embC | 4241053 | c.1191G>T | synonymous_variant | 0.77 | ethambutol | |
embC | 4241086 | c.1224G>C | synonymous_variant | 0.83 | ethambutol | |
embC | 4241104 | c.1242G>A | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.89 | ethambutol | |
embC | 4241110 | c.1248G>C | synonymous_variant | 0.88 | ethambutol | |
embC | 4241113 | c.1251G>C | synonymous_variant | 0.87 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.86 | ethambutol | Not assoc w R - Interim |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.71 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.71 | ethambutol | |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.67 | ethambutol | |
embC | 4241230 | c.1368A>G | synonymous_variant | 0.64 | ethambutol | |
embC | 4241361 | p.Asn500Thr | missense_variant | 0.44 | ethambutol | |
embC | 4241363 | p.Leu501Met | missense_variant | 0.44 | ethambutol | |
embC | 4241371 | c.1509G>A | synonymous_variant | 0.45 | ethambutol | |
embC | 4241374 | c.1512T>C | synonymous_variant | 0.48 | ethambutol | |
embC | 4241380 | c.1518A>G | synonymous_variant | 0.48 | ethambutol | |
embC | 4241392 | c.1530G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241394 | p.Lys511Ser | missense_variant | 0.5 | ethambutol | |
embC | 4241411 | p.Ile517Leu | missense_variant | 0.46 | ethambutol | |
embC | 4241608 | c.1746C>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4241611 | c.1749G>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4241614 | c.1752A>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4241626 | c.1764T>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241644 | c.1782G>C | synonymous_variant | 0.46 | ethambutol | |
embC | 4241648 | c.1786T>C | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
embC | 4242070 | c.2208T>C | synonymous_variant | 0.58 | ethambutol | |
embC | 4242073 | c.2211C>T | synonymous_variant | 0.58 | ethambutol | Not assoc w R - Interim |
embC | 4242076 | c.2214G>C | synonymous_variant | 0.58 | ethambutol | |
embC | 4242079 | c.2217T>C | synonymous_variant | 0.58 | ethambutol | |
embC | 4242085 | c.2223A>G | synonymous_variant | 0.52 | ethambutol | |
embC | 4242095 | p.Ala745Thr | missense_variant | 0.52 | ethambutol | Uncertain significance |
embC | 4242100 | c.2238C>G | synonymous_variant | 0.52 | ethambutol | |
embC | 4242104 | p.Thr748Ser | missense_variant | 0.52 | ethambutol | |
embC | 4242138 | p.Leu759Gln | missense_variant | 0.64 | ethambutol | |
embC | 4242142 | c.2280T>C | synonymous_variant | 0.61 | ethambutol | |
embC | 4242151 | c.2289A>G | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embC | 4242154 | c.2292C>G | synonymous_variant | 0.47 | ethambutol | |
embA | 4244324 | c.1092T>G | synonymous_variant | 0.5 | ethambutol | |
embA | 4244327 | c.1095T>C | synonymous_variant | 0.54 | ethambutol | |
embA | 4244337 | p.Leu369Val | missense_variant | 0.52 | ethambutol | |
embA | 4244340 | p.Ser370Ala | missense_variant | 0.54 | ethambutol | |
embA | 4244345 | c.1113C>G | synonymous_variant | 0.59 | ethambutol | |
embA | 4244372 | c.1140T>G | synonymous_variant | 0.62 | ethambutol | |
embA | 4244378 | c.1146G>A | synonymous_variant | 0.63 | ethambutol | Not assoc w R - Interim |
embA | 4244543 | c.1311C>G | synonymous_variant | 0.62 | ethambutol | |
embA | 4244547 | p.Ile439Val | missense_variant | 0.67 | ethambutol | |
embA | 4244557 | p.Arg442Thr | missense_variant | 0.65 | ethambutol | |
embA | 4244561 | c.1329C>T | synonymous_variant | 0.65 | ethambutol | |
embA | 4244582 | c.1350T>C | synonymous_variant | 0.6 | ethambutol | |
embA | 4244612 | c.1380C>G | synonymous_variant | 0.61 | ethambutol | |
embA | 4244615 | c.1383G>C | synonymous_variant | 0.61 | ethambutol | |
embA | 4244616 | p.Ala462Ser | missense_variant | 0.61 | ethambutol | |
embA | 4244619 | c.1387T>C | synonymous_variant | 0.58 | ethambutol | |
embA | 4244631 | p.Thr467Leu | missense_variant | 0.62 | ethambutol | |
embA | 4244645 | c.1413T>C | synonymous_variant | 0.67 | ethambutol | |
embA | 4244648 | c.1416G>C | synonymous_variant | 0.67 | ethambutol | |
embA | 4244650 | p.Asp473Gly | missense_variant | 0.64 | ethambutol | Uncertain significance |
embA | 4244663 | c.1431C>A | synonymous_variant | 0.71 | ethambutol | |
embA | 4244669 | c.1437G>C | synonymous_variant | 0.7 | ethambutol | |
embA | 4244671 | p.Ala480Gly | missense_variant | 0.7 | ethambutol | |
embA | 4244681 | c.1449A>C | synonymous_variant | 0.68 | ethambutol | |
embA | 4244720 | c.1488C>T | synonymous_variant | 0.47 | ethambutol | |
embA | 4245056 | c.1824C>G | synonymous_variant | 0.62 | ethambutol | |
embA | 4245060 | c.1828T>C | synonymous_variant | 0.65 | ethambutol | |
embA | 4245072 | p.Leu614Val | missense_variant | 0.68 | ethambutol | |
embA | 4245078 | p.Trp616Val | missense_variant | 0.66 | ethambutol | |
embA | 4245083 | c.1851A>G | synonymous_variant | 0.67 | ethambutol | Not assoc w R - Interim |
embA | 4245093 | p.Ile621Val | missense_variant | 0.75 | ethambutol | Uncertain significance |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.75 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.72 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.74 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.71 | ethambutol | |
embA | 4245186 | p.Thr652Ala | missense_variant | 0.68 | ethambutol | |
embA | 4245198 | p.Leu656Ala | missense_variant | 0.71 | ethambutol | |
embA | 4245206 | c.1974A>C | synonymous_variant | 0.71 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.71 | ethambutol | |
embA | 4245215 | c.1983A>C | synonymous_variant | 0.74 | ethambutol | |
embA | 4245222 | p.Tyr664Gln | missense_variant | 0.71 | ethambutol | |
embB | 4245668 | c.-846C>G | upstream_gene_variant | 0.55 | ethambutol | |
embA | 4245674 | c.2442A>C | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embA | 4245705 | p.His825Asn | missense_variant | 0.56 | ethambutol | |
embA | 4245708 | p.Ala826Ile | missense_variant | 0.56 | ethambutol | |
embB | 4245726 | c.-788_-786delTTGinsCTC | upstream_gene_variant | 0.62 | ethambutol | |
embB | 4245737 | c.-777A>C | upstream_gene_variant | 0.67 | ethambutol | |
embB | 4245740 | c.-774T>C | upstream_gene_variant | 0.77 | ethambutol | |
embA | 4246020 | p.Ala930Thr | missense_variant | 0.39 | ethambutol | |
embB | 4246040 | c.-474C>G | upstream_gene_variant | 0.39 | ethambutol | |
embA | 4246055 | c.2823T>C | synonymous_variant | 0.37 | ethambutol | Not assoc w R - Interim |
embB | 4246064 | c.-450T>C | upstream_gene_variant | 0.37 | ethambutol | |
embA | 4246080 | p.Pro950Ser | missense_variant | 0.44 | ethambutol | |
embA | 4246085 | p.Glu951Asp | missense_variant | 0.44 | ethambutol | Not assoc w R |
embA | 4246088 | c.2856A>G | synonymous_variant | 0.44 | ethambutol | Not assoc w R |
embB | 4246097 | c.-417C>G | upstream_gene_variant | 0.4 | ethambutol | |
embA | 4246359 | p.Ala1043Ser | missense_variant | 0.37 | ethambutol | |
embB | 4246367 | c.-147C>T | upstream_gene_variant | 0.37 | ethambutol | |
embB | 4246373 | c.-141T>G | upstream_gene_variant | 0.37 | ethambutol | |
embB | 4246376 | c.-138G>C | upstream_gene_variant | 0.37 | ethambutol | |
embB | 4246400 | c.-114G>C | upstream_gene_variant | 0.4 | ethambutol | |
embB | 4247348 | p.Thr279Ala | missense_variant | 0.4 | ethambutol | |
embB | 4247355 | p.Ala281Val | missense_variant | 0.4 | ethambutol | Uncertain significance |
embB | 4247357 | p.Val282Thr | missense_variant | 0.38 | ethambutol | |
embB | 4247365 | c.852A>C | synonymous_variant | 0.44 | ethambutol | |
embB | 4247367 | p.Phe285Ser | missense_variant | 0.44 | ethambutol | |
embB | 4247370 | p.Gly286Ala | missense_variant | 0.44 | ethambutol | |
embB | 4247375 | p.Leu288Val | missense_variant | 0.5 | ethambutol | |
embB | 4247380 | c.867C>G | synonymous_variant | 0.58 | ethambutol | |
embB | 4247389 | c.876C>G | synonymous_variant | 0.58 | ethambutol | |
embB | 4247395 | c.882C>G | synonymous_variant | 0.56 | ethambutol | |
embB | 4247401 | c.888T>C | synonymous_variant | 0.56 | ethambutol | |
embB | 4247404 | c.891G>C | synonymous_variant | 0.62 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.7 | ethambutol | Not assoc w R - Interim |
embB | 4247464 | c.951C>G | synonymous_variant | 0.77 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.77 | ethambutol | |
embB | 4247485 | c.972C>T | synonymous_variant | 0.8 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.77 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.73 | ethambutol | |
embB | 4247544 | p.Ser344Thr | missense_variant | 0.76 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.76 | ethambutol | |
embB | 4247722 | c.1209G>C | synonymous_variant | 0.62 | ethambutol | |
embB | 4247725 | c.1212G>C | synonymous_variant | 0.62 | ethambutol | |
embB | 4247729 | p.Gly406Pro | missense_variant | 0.62 | ethambutol | |
embB | 4247740 | c.1227G>C | synonymous_variant | 0.62 | ethambutol | |
embB | 4247741 | p.Leu410Val | missense_variant | 0.62 | ethambutol | |
embB | 4247746 | c.1233C>G | synonymous_variant | 0.57 | ethambutol | |
embB | 4247753 | p.Val414Ile | missense_variant | 0.5 | ethambutol | Uncertain significance |
embB | 4247797 | c.1284C>G | synonymous_variant | 0.59 | ethambutol | |
embB | 4247800 | c.1287A>T | synonymous_variant | 0.53 | ethambutol | |
embB | 4247803 | c.1290G>C | synonymous_variant | 0.59 | ethambutol | |
embB | 4247815 | c.1302C>G | synonymous_variant | 0.61 | ethambutol | |
embB | 4247819 | p.Val436Ile | missense_variant | 0.65 | ethambutol | Uncertain significance |
embB | 4247827 | c.1314C>G | synonymous_variant | 0.65 | ethambutol | |
embB | 4247830 | c.1317A>G | synonymous_variant | 0.65 | ethambutol | Not assoc w R - Interim |
embB | 4247836 | c.1323A>C | synonymous_variant | 0.71 | ethambutol | Not assoc w R - Interim |
embB | 4247839 | c.1326G>C | synonymous_variant | 0.64 | ethambutol | Not assoc w R - Interim |
embB | 4247842 | c.1329T>C | synonymous_variant | 0.64 | ethambutol | |
embB | 4247851 | c.1338C>T | synonymous_variant | 0.7 | ethambutol | Not assoc w R - Interim |
embB | 4247857 | c.1344C>T | synonymous_variant | 0.68 | ethambutol | |
embB | 4247858 | c.1345C>T | synonymous_variant | 0.68 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 0.68 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 0.69 | ethambutol | Not assoc w R - Interim |
embB | 4247899 | p.Met462Ile | missense_variant | 0.71 | ethambutol | |
embB | 4247905 | c.1392G>T | synonymous_variant | 0.68 | ethambutol | |
embB | 4247908 | c.1395C>T | synonymous_variant | 0.69 | ethambutol | |
embB | 4247909 | c.1396T>C | synonymous_variant | 0.69 | ethambutol | |
embB | 4247914 | c.1401G>C | synonymous_variant | 0.7 | ethambutol | Not assoc w R - Interim |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.68 | ethambutol | |
embB | 4247944 | c.1431G>A | synonymous_variant | 0.67 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.68 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.68 | ethambutol | |
embB | 4247965 | c.1452C>G | synonymous_variant | 0.67 | ethambutol | |
embB | 4247968 | c.1455C>A | synonymous_variant | 0.67 | ethambutol | |
embB | 4247992 | c.1479G>A | synonymous_variant | 0.63 | ethambutol | Not assoc w R - Interim |
embB | 4248007 | c.1494C>G | synonymous_variant | 0.7 | ethambutol | |
embB | 4248035 | p.Val508Ile | missense_variant | 0.78 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.76 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ser | missense_variant | 0.76 | ethambutol | |
embB | 4248052 | c.1539G>C | synonymous_variant | 0.78 | ethambutol | Not assoc w R - Interim |
embB | 4248055 | c.1542G>C | synonymous_variant | 0.78 | ethambutol | |
embB | 4248064 | c.1551G>C | synonymous_variant | 0.81 | ethambutol | Not assoc w R - Interim |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.78 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.72 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.62 | ethambutol | |
embB | 4248100 | c.1587C>T | synonymous_variant | 0.55 | ethambutol | Not assoc w R - Interim |
embB | 4248118 | c.1605T>C | synonymous_variant | 0.53 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4248139 | c.1626C>G | synonymous_variant | 0.47 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.47 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.47 | ethambutol | |
embB | 4248146 | p.Ile545Val | missense_variant | 0.55 | ethambutol | |
embB | 4248149 | p.Thr546Ala | missense_variant | 0.61 | ethambutol | Uncertain significance |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.61 | ethambutol | Not assoc w R - Interim |
embB | 4248163 | c.1650G>C | synonymous_variant | 0.61 | ethambutol | |
embB | 4248169 | c.1656C>G | synonymous_variant | 0.69 | ethambutol | |
embB | 4248175 | c.1662G>T | synonymous_variant | 0.71 | ethambutol | |
embB | 4248178 | c.1665C>T | synonymous_variant | 0.71 | ethambutol | |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.74 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.73 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.7 | ethambutol | Uncertain significance |
embB | 4248214 | c.1701C>G | synonymous_variant | 0.76 | ethambutol | |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.78 | ethambutol | |
embB | 4248226 | c.1713G>C | synonymous_variant | 0.79 | ethambutol | |
embB | 4248241 | c.1728C>T | synonymous_variant | 0.83 | ethambutol | |
embB | 4248277 | c.1764G>C | synonymous_variant | 0.76 | ethambutol | |
embB | 4248280 | c.1767C>G | synonymous_variant | 0.76 | ethambutol | |
embB | 4248316 | c.1803C>G | synonymous_variant | 0.7 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.68 | ethambutol | |
embB | 4248322 | c.1809G>A | synonymous_variant | 0.68 | ethambutol | Not assoc w R - Interim |
embB | 4248338 | c.1825C>T | synonymous_variant | 0.66 | ethambutol | |
embB | 4248346 | c.1833G>T | synonymous_variant | 0.55 | ethambutol | |
embB | 4248442 | c.1929C>G | synonymous_variant | 0.57 | ethambutol | |
embB | 4248463 | c.1950C>G | synonymous_variant | 0.57 | ethambutol | |
embB | 4248468 | p.Tyr652Phe | missense_variant | 0.57 | ethambutol | |
embB | 4248472 | c.1959T>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4248486 | p.Ser658Asn | missense_variant | 0.43 | ethambutol | |
embB | 4248489 | p.Ala659Val | missense_variant | 0.43 | ethambutol | |
embB | 4248498 | p.Lys662Arg | missense_variant | 0.46 | ethambutol | |
embB | 4248500 | p.Ile663Phe | missense_variant | 0.46 | ethambutol | |
embB | 4248503 | p.Asp664His | missense_variant | 0.46 | ethambutol | |
embB | 4248508 | c.1995G>A | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embB | 4248513 | p.Thr667Ser | missense_variant | 0.46 | ethambutol | |
embB | 4248524 | p.Ile671Val | missense_variant | 0.46 | ethambutol | |
aftB | 4267579 | p.His420Asn | missense_variant | 0.64 | ethambutol | |
aftB | 4267580 | c.1257G>C | synonymous_variant | 0.64 | ethambutol | |
aftB | 4267594 | p.Ala415Ser | missense_variant | 0.59 | ethambutol | |
aftB | 4267607 | c.1230G>A | synonymous_variant | 0.62 | ethambutol | |
aftB | 4267619 | c.1218C>A | synonymous_variant | 0.55 | ethambutol | |
aftB | 4267622 | c.1215G>C | synonymous_variant | 0.55 | ethambutol | |
aftB | 4267625 | c.1212T>C | synonymous_variant | 0.55 | ethambutol | |
aftB | 4267634 | p.Arg401His | missense_variant | 0.48 | ethambutol | |
aftB | 4267647 | p.Asp397Gly | missense_variant | 0.69 | ethambutol | Not assoc w R |
aftB | 4268081 | c.756A>G | synonymous_variant | 0.56 | ethambutol | |
aftB | 4268084 | c.753G>C | synonymous_variant | 0.61 | ethambutol | |
aftB | 4268096 | c.741C>G | synonymous_variant | 0.61 | ethambutol | |
aftB | 4268099 | c.738G>C | synonymous_variant | 0.61 | ethambutol | |
aftB | 4268102 | c.735C>G | synonymous_variant | 0.67 | ethambutol | Not assoc w R - Interim |
aftB | 4268105 | c.732T>C | synonymous_variant | 0.68 | ethambutol | |
aftB | 4268117 | c.720G>C | synonymous_variant | 0.78 | ethambutol | |
aftB | 4268123 | p.Ser238Gly | missense_variant | 0.75 | ethambutol | |
aftB | 4268129 | c.708T>A | synonymous_variant | 0.74 | ethambutol | |
aftB | 4268138 | c.699A>C | synonymous_variant | 0.74 | ethambutol | Not assoc w R - Interim |
aftB | 4268144 | c.693T>C | synonymous_variant | 0.74 | ethambutol | |
aftB | 4268164 | p.Gln225Glu | missense_variant | 0.78 | ethambutol | |
aftB | 4268171 | c.666G>C | synonymous_variant | 0.79 | ethambutol | |
aftB | 4268179 | c.658T>C | synonymous_variant | 0.74 | ethambutol | Not assoc w R - Interim |
aftB | 4268182 | p.Phe219Leu | missense_variant | 0.7 | ethambutol | |
aftB | 4268183 | c.654A>T | synonymous_variant | 0.7 | ethambutol | |
aftB | 4268186 | c.651C>G | synonymous_variant | 0.7 | ethambutol | |
aftB | 4268194 | p.Leu215Val | missense_variant | 0.75 | ethambutol | |
aftB | 4268207 | c.630C>G | synonymous_variant | 0.65 | ethambutol | |
aftB | 4268210 | c.627C>T | synonymous_variant | 0.62 | ethambutol | |
aftB | 4268222 | c.615G>C | synonymous_variant | 0.6 | ethambutol | |
aftB | 4268225 | c.612G>C | synonymous_variant | 0.57 | ethambutol | |
aftB | 4268228 | c.609C>G | synonymous_variant | 0.57 | ethambutol | |
aftB | 4268233 | p.Ile202Val | missense_variant | 0.57 | ethambutol | Uncertain significance |
aftB | 4268236 | c.601T>C | synonymous_variant | 0.57 | ethambutol | |
aftB | 4268386 | c.451T>C | synonymous_variant | 0.56 | ethambutol | |
aftB | 4268393 | c.444G>C | synonymous_variant | 0.56 | ethambutol | Not assoc w R - Interim |
aftB | 4268404 | c.433T>C | synonymous_variant | 0.6 | ethambutol | |
aftB | 4268406 | p.Val144Ala | missense_variant | 0.6 | ethambutol | |
aftB | 4268410 | c.427C>T | synonymous_variant | 0.6 | ethambutol | Not assoc w R - Interim |
aftB | 4268417 | c.420G>A | synonymous_variant | 0.64 | ethambutol | |
aftB | 4268423 | c.414C>G | synonymous_variant | 0.6 | ethambutol | |
aftB | 4268441 | c.396C>G | synonymous_variant | 0.53 | ethambutol | |
aftB | 4268444 | c.393C>G | synonymous_variant | 0.53 | ethambutol | Not assoc w R - Interim |
aftB | 4268994 | c.-158T>G | upstream_gene_variant | 0.61 | ethambutol | |
aftB | 4269006 | c.-170T>C | upstream_gene_variant | 0.67 | ethambutol | |
aftB | 4269012 | c.-176G>C | upstream_gene_variant | 0.64 | ethambutol | |
ubiA | 4269015 | c.819G>A | synonymous_variant | 0.64 | ethambutol | Not assoc w R - Interim |
aftB | 4269018 | c.-182G>C | upstream_gene_variant | 0.61 | ethambutol | |
aftB | 4269027 | c.-191C>G | upstream_gene_variant | 0.61 | ethambutol | |
aftB | 4269033 | c.-197T>C | upstream_gene_variant | 0.56 | ethambutol | |
aftB | 4269036 | c.-200C>G | upstream_gene_variant | 0.56 | ethambutol | |
aftB | 4269042 | c.-206G>C | upstream_gene_variant | 0.58 | ethambutol | |
ubiA | 4269075 | p.Ile253Val | missense_variant | 0.6 | ethambutol | |
ubiA | 4269080 | p.Met252Leu | missense_variant | 0.61 | ethambutol | |
aftB | 4269177 | c.-341G>T | upstream_gene_variant | 0.56 | ethambutol | |
aftB | 4269186 | c.-350C>A | upstream_gene_variant | 0.73 | ethambutol | |
aftB | 4269201 | c.-365A>G | upstream_gene_variant | 0.81 | ethambutol | |
aftB | 4269204 | c.-368G>C | upstream_gene_variant | 0.81 | ethambutol | |
aftB | 4269210 | c.-374G>A | upstream_gene_variant | 0.88 | ethambutol | |
ubiA | 4269220 | p.Ala205Lys | missense_variant | 0.81 | ethambutol | |
ubiA | 4269222 | c.612T>C | synonymous_variant | 0.81 | ethambutol | Not assoc w R - Interim |
aftB | 4269234 | c.-398A>G | upstream_gene_variant | 0.84 | ethambutol | |
ubiA | 4269240 | p.Leu198Val | missense_variant | 0.81 | ethambutol | Uncertain significance |
ubiA | 4269243 | p.His197Gln | missense_variant | 0.81 | ethambutol | |
aftB | 4269267 | c.-431C>G | upstream_gene_variant | 0.75 | ethambutol | |
aftB | 4269564 | c.-728G>C | upstream_gene_variant | 0.63 | ethambutol | |
aftB | 4269573 | c.-737A>G | upstream_gene_variant | 0.65 | ethambutol | |
ubiA | 4269585 | c.249G>A | synonymous_variant | 0.61 | ethambutol | Not assoc w R - Interim |
aftB | 4269588 | c.-752G>C | upstream_gene_variant | 0.61 | ethambutol | |
aftB | 4269591 | c.-755C>T | upstream_gene_variant | 0.61 | ethambutol | |
ubiA | 4269606 | c.228T>C | synonymous_variant | 0.59 | ethambutol | Not assoc w R |
aftB | 4269609 | c.-773G>C | upstream_gene_variant | 0.56 | ethambutol | |
aftB | 4269621 | c.-785C>G | upstream_gene_variant | 0.54 | ethambutol | |
ubiA | 4269624 | c.210C>T | synonymous_variant | 0.64 | ethambutol | Not assoc w R - Interim |
ubiA | 4269632 | p.Ala68Ser | missense_variant | 0.64 | ethambutol | |
ethA | 4327674 | c.-201C>G | upstream_gene_variant | 0.45 | ethionamide | |
ethA | 4327680 | c.-207A>G | upstream_gene_variant | 0.48 | ethionamide | |
ethA | 4327686 | c.-213C>G | upstream_gene_variant | 0.48 | ethionamide | |
ethR | 4327714 | p.Ile56Leu | missense_variant | 0.54 | ethionamide | |
ethA | 4327719 | c.-246C>G | upstream_gene_variant | 0.52 | ethionamide | |
ethA | 4327720 | c.-247T>G | upstream_gene_variant | 0.54 | ethionamide | |
ethA | 4327734 | c.-261G>A | upstream_gene_variant | 0.57 | ethionamide | |
ethR | 4327755 | p.Glu69Asp | missense_variant | 0.52 | ethionamide | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
whiB6 | 4338794 | c.-273A>G | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Not assoc w R |