Run ID: SRR5341456
Sample name:
Date: 2024-04-15T12:55:42.558494
Number of reads: 797339
Percentage reads mapped: 15.16
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| La1.2.BCG | M.bovis | None | 0.11 |
| lineage6.1.3 | West-Africa 2 | RD702 | 0.09 |
| lineage4 | Euro-American | None | 0.89 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.91 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | gyrB | p.Thr500Asn | Uncertain significance | Mutation from literature |
| ofloxacin | ||||
| levofloxacin | gyrB | p.Thr500Asn | Uncertain significance | Mutation from literature |
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.421_423delCAGinsGA | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| fbiC | c.550_552delCAAinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.2544_*717del | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiA | c.253_255delACTinsTC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| gyrB | 6738 | p.Thr500Asn | missense_variant | 1.0 | levofloxacin | Uncertain significance | Mutation from literature |
| moxifloxacin | Uncertain significance | Mutation from literature | |||||
| fgd1 | 491203 | c.421_423delCAGinsGA | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303480 | c.550_552delCAAinsGG | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305473 | c.2544_*717del | frameshift_variant&stop_lost&splice_region_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiA | 3640795 | c.253_255delACTinsTC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 699 | c.699G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 720 | c.720G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 723 | c.723A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 747 | c.747G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 750 | c.750C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 753 | c.753C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 759 | c.759C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 768 | c.768C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 771 | c.771A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 777 | c.777A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 789 | c.789C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 793 | c.793_795delGTAinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 798 | c.798C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 834 | c.834C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 837 | c.837A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 864 | c.864C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 877 | c.877T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 903 | c.903C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 927 | c.927G>A | synonymous_variant | 0.94 | isoniazid | |
| dnaA | 933 | c.933C>T | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 942 | c.942C>G | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 948 | c.948C>T | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 955 | c.955_957delAGAinsCG | frameshift_variant&synonymous_variant | 0.95 | isoniazid | Uncertain significance |
| dnaA | 969 | c.969G>A | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 975 | c.975G>A | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
| dnaA | 984 | c.984T>C | synonymous_variant | 0.92 | isoniazid | Not assoc w R - Interim |
| gyrB | 6256 | c.1017G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6262 | c.1023G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6304 | c.-998C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6316 | c.-986G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6326 | c.-976_-974delAGCinsTCG | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6329 | p.Glu364Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6526 | c.-776T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6532 | c.-770C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6535 | c.-767C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6541 | c.1302C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6542 | p.Ile435Leu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6547 | c.-755T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6556 | c.-746C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6563 | c.1324C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6571 | c.-731T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6577 | c.-725T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6582 | p.Thr448Asn | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6586 | c.-716T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6590 | p.Arg451Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6688 | c.-614C>A | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6724 | c.-578G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6733 | c.-569G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6742 | c.-560A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6763 | c.1524G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6764 | c.-538C>T | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6775 | c.1536G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6802 | c.1563G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7313 | c.12G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7317 | c.16T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7325 | c.24delTinsCGGG | conservative_inframe_insertion&synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7335 | c.34_36delCTCinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7412 | c.111C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7433 | c.132G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7466 | c.165G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7475 | c.174A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7487 | c.186C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7490 | c.189C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7511 | c.210C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7520 | c.219G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7529 | c.228G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7625 | c.324G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7626 | c.325C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7661 | c.360C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7671 | p.Pro124Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7676 | c.375G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382_384delAGGinsCT | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7733 | c.432A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7742 | c.441G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7758 | c.457_459delATCinsGA | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7781 | c.480G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7790 | c.489G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7797 | c.496_498delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7808 | c.507G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7835 | c.534A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7838 | c.537C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7853 | c.552C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7886 | c.585T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7898 | p.Asp199Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8312 | c.1011G>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8330 | c.1029C>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8339 | c.1038A>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 0.95 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8354 | c.1053G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8366 | c.1065G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8390 | c.1089C>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8393 | c.1092T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8399 | c.1098T>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8401 | p.Asp367Ala | missense_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8408 | c.1107A>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8414 | c.1113C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8426 | c.1125G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8433 | p.Thr378Arg | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8444 | c.1143G>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8454 | c.1153_1155delAACinsGG | frameshift_variant&missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8501 | c.1200G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8510 | c.1209G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8528 | c.1227G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8531 | c.1230G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8535 | p.Glu412Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8783 | c.1482G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8817 | p.Ser506Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8849 | c.1548C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8933 | c.1632G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8945 | c.1644G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9017 | c.1716C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9064 | p.Ser588Leu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9086 | c.1785C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9113 | c.1812C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9329 | c.2028C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9356 | c.2055G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9369 | c.2068C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9419 | c.2118T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9420 | p.Ile707Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9425 | c.2124C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9443 | c.2142G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9449 | c.2148C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9452 | c.2151G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9455 | c.2154T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9458 | c.2157A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9460 | p.Gly720Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9479 | c.2178G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491151 | c.369G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491171 | p.Ala130Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491184 | c.402A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491223 | c.441C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491238 | c.456C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491248 | p.Arg156Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491277 | c.495G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491280 | c.498C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491284 | p.Gly168Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491289 | c.507C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491316 | c.534C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491334 | c.552C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491337 | c.555C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491340 | c.558C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491345 | p.Ala188Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491373 | c.591C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491397 | c.615G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491409 | c.627G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491472 | c.690A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491490 | c.708C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491496 | c.714C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491499 | c.717G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491502 | c.720G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491523 | c.741G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491541 | c.759G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491546 | p.Thr255Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491563 | c.781_782delAGinsTC | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491598 | c.816C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575701 | c.354G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575714 | p.Tyr123Asn | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575752 | c.405G>A | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575761 | c.414C>T | synonymous_variant | 0.98 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575770 | c.423G>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575772 | p.Val142Ala | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575795 | c.448_450delATCinsGG | frameshift_variant&missense_variant | 0.98 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575803 | c.456C>T | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575809 | c.462C>T | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575818 | c.471G>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| mshA | 575833 | c.486C>T | synonymous_variant | 0.97 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575842 | c.495G>T | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| mshA | 575843 | p.Arg166Ala | missense_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575878 | c.531A>C | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575885 | c.538C>T | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575892 | p.Ala182Gly | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575905 | c.558G>C | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575916 | p.Asp190Ala | missense_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619588 | c.-303C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619607 | c.-284_-282delCTGinsAC | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619613 | c.-278_-276delGTCinsCG | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619619 | c.-272C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619627 | c.-264C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619629 | c.-262G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619634 | c.-257_-256delTCinsCT | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619647 | c.-244_-243delTCinsGG | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619654 | c.-237A>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619657 | c.-234C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619669 | c.-222G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619672 | c.-219A>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619676 | c.-215C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620337 | c.447C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620343 | c.453G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620349 | c.459A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620352 | c.462C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620366 | p.Asn159Thr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620418 | c.528G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620563 | c.673C>T | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620569 | c.679_681delGGAinsCG | frameshift_variant&missense_variant | 0.93 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620585 | p.Thr232Ser | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620607 | c.717T>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620613 | c.723C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620634 | c.744C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620643 | c.753C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620648 | p.Glu253Gly | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620703 | c.813G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620712 | c.822G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620736 | c.846G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620742 | c.852G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620758 | p.Arg290Tyr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620766 | c.876C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620783 | p.Ala298Val | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| hadA | 731717 | c.-213T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731726 | c.-204C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731729 | c.-201C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731753 | c.-177A>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731795 | c.-135C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731810 | c.-120G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731816 | c.-114G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731831 | c.-99G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731840 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731843 | c.-87T>C | upstream_gene_variant | 1.0 | isoniazid | |
| nusG | 734383 | p.Ser44Ala | missense_variant | 0.91 | rifampicin | |
| nusG | 734391 | c.138C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
| nusG | 734415 | c.162C>T | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734424 | c.171G>T | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734472 | c.219T>C | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734571 | c.318C>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734586 | c.333G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734614 | c.361_363delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734625 | c.372T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734787 | c.534T>G | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734794 | p.Val181Ile | missense_variant | 0.94 | rifampicin | Uncertain significance |
| nusG | 734814 | c.561G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734820 | c.567A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| nusG | 734826 | c.573A>C | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734841 | c.588G>T | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734850 | c.597C>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734863 | c.610_612delACGinsTC | frameshift_variant&missense_variant | 0.98 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734913 | c.660C>G | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734922 | c.669C>T | synonymous_variant | 0.96 | rifampicin | |
| nusG | 734928 | c.675A>G | synonymous_variant | 0.96 | rifampicin | |
| nusG | 734934 | c.681G>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| nusG | 734940 | c.687G>A | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760059 | c.253_255delTACinsGA | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoB | 760067 | c.261G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760070 | c.264T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760148 | p.Asp114Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760151 | c.345G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760155 | p.Lys117Arg | missense_variant | 1.0 | rifampicin | |
| rpoB | 760178 | c.372G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760199 | c.393C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760316 | c.510C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760317 | c.511_512delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760337 | c.531C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760354 | p.Glu183Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760357 | p.Thr184Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760400 | c.594G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760415 | c.609C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760449 | p.Thr215Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760460 | c.654G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760463 | c.657C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760490 | c.684C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760508 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760521 | c.715_716delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Arg | missense_variant | 0.97 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.98 | rifampicin | Uncertain significance |
| rpoB | 760587 | p.Thr261Ala | missense_variant | 0.98 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.98 | rifampicin | |
| rpoB | 760593 | p.Gly263Asn | missense_variant | 0.98 | rifampicin | |
| rpoB | 760596 | p.Thr264Ser | missense_variant | 0.98 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760649 | c.843G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760718 | c.912C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760721 | c.915C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760734 | p.Val310Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 760877 | c.1071G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760880 | c.1074G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760883 | c.1077G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760887 | p.Thr361Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760965 | p.Met387Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760970 | c.1164G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761124 | c.1318C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761180 | c.1374A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761201 | c.1395G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761204 | c.1398C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761222 | c.1416G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761240 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761258 | c.1452G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761318 | c.1512G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761333 | c.1527G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761345 | c.1539G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761348 | c.1542C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761357 | c.1551G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761516 | c.1710G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761534 | c.1728G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761651 | c.1845C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761669 | c.1863C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761711 | c.1905C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761712 | p.Val636Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 761724 | c.1918_1920delGAAinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761728 | p.Ser641Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761760 | p.Ile652Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761768 | c.1962G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761777 | c.1971C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761814 | p.Ala670Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761847 | c.2041_2043delTGCinsCT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761868 | c.2062_2064delGACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761876 | c.2070C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761880 | p.Ala692Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761897 | c.2091C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761903 | c.2097T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762006 | c.2200_2202delCGCinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762024 | p.Val740Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762134 | c.2328C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762209 | c.2403C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762212 | c.2406G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762218 | c.2412T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762236 | c.2430G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762246 | c.2440C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762281 | c.2475G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.99 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 762374 | c.-996G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.98 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 762407 | c.-963G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 762410 | c.2604T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 762449 | c.-921C>T | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 762452 | c.2646G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762470 | c.-900G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762476 | c.-894C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762490 | p.Val895Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 762512 | c.-858C>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 762521 | c.-849C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762527 | c.-843G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762560 | c.2754A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 762563 | c.-807G>T | upstream_gene_variant | 0.96 | rifampicin | |
| rpoC | 762575 | c.-795C>T | upstream_gene_variant | 0.94 | rifampicin | |
| rpoB | 762736 | p.Ala977Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 762753 | c.2947T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762758 | c.-612G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762760 | p.Cys985Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762768 | p.Pro988Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762788 | c.2982G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762795 | p.Asp997Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | p.Met1003Arg | missense_variant | 1.0 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762831 | c.3025_3026delAGinsTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762894 | c.3088C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762911 | c.-459C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762917 | c.3111C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762920 | c.3114C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762957 | c.3151C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763050 | c.-320C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763053 | c.3247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763058 | c.-312C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763076 | c.-294C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763082 | c.3276C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763133 | c.-237G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763190 | c.-180C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763193 | c.-177C>T | upstream_gene_variant | 0.98 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763203 | p.Ser1133Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 763207 | p.Ser1134Lys | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763235 | p.Glu1143Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763262 | c.-108C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763265 | c.-105G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763283 | c.3477T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763352 | c.-18T>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763396 | c.27A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763447 | c.78C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763465 | c.96G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763492 | c.123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763495 | c.126G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763501 | c.132C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763505 | c.136C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763606 | c.237C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763618 | c.249C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763657 | c.288G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763705 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763708 | c.339G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763709 | c.340C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763735 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 0.93 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 0.93 | rifampicin | |
| rpoC | 763879 | c.510A>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763888 | c.519G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763903 | c.534G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763919 | c.550C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763930 | c.561G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763947 | p.Ala193Val | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoC | 763951 | c.582G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763960 | c.591T>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764059 | c.690G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764075 | p.Val236Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764085 | p.Asn239Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764087 | p.Leu240Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764104 | c.735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764110 | c.741C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764169 | p.Asn267Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764207 | p.Val280Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764213 | p.Arg282Lys | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764242 | c.873C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764245 | c.876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764254 | c.885G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764287 | c.918C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764293 | c.924G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764317 | c.948C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764329 | c.960C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764344 | c.975C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764383 | c.1014C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764410 | c.1041G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764455 | c.1086G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764524 | c.1155C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764534 | c.1165C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764548 | c.1179G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764573 | c.1204_1206delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764623 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764635 | c.1266C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764644 | c.1275G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764656 | c.1287C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764671 | c.1302G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764713 | c.1344G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764863 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764896 | c.1527C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764962 | c.1593G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764983 | c.1614T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765085 | c.1716T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765115 | c.1746G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765277 | c.1908G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765281 | p.Thr638Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765304 | p.Glu645Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 765305 | c.1936_1938delATCinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765311 | p.Ala648Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765325 | c.1956C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765339 | p.Gln657Arg | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765348 | p.Asp660Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765358 | p.Met663Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765404 | p.Leu679Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765445 | c.2076G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765453 | p.Ala695Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765505 | c.2136C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765533 | p.Tyr722His | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765544 | c.2175C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765547 | c.2178C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765548 | c.2179_2181delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765625 | c.2256C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765635 | c.2266_2268delGTCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765640 | c.2271A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765661 | c.2292T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765662 | c.2293_2295delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765669 | p.His767Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765705 | p.Lys779Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765718 | p.Asp783Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765721 | c.2352G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765724 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765742 | p.Glu791Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765817 | c.2448G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765908 | c.2539C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765947 | c.2578T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765961 | c.2592G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765962 | c.2593T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765973 | c.2604C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766003 | c.2634G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766012 | c.2643C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766258 | c.2889T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766270 | c.2901G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766273 | c.2904T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766280 | c.2911_2913delAGCinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766288 | c.2919C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766291 | c.2922G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766294 | c.2925C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766297 | c.2928G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766309 | c.2940G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766312 | c.2943T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766351 | c.2982C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766375 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766387 | c.3018C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766390 | c.3021C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766408 | c.3039C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766435 | p.Glu1022Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766459 | c.3090G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766504 | c.3135G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766517 | p.Thr1050Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766530 | p.Arg1054Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766534 | c.3165C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766537 | c.3168G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766547 | p.Arg1060Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766564 | c.3195C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766582 | c.3213C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | c.3238_3240delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766610 | p.Ser1081Pro | missense_variant | 1.0 | rifampicin | |
| rpoC | 766618 | c.3249G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766654 | c.3285C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766661 | p.Val1098Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766702 | c.3333G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766708 | c.3339A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766747 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766753 | c.3384C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766775 | p.Arg1136Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 766787 | p.Glu1140Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766859 | c.3490C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766961 | p.Gly1198Leu | missense_variant | 0.93 | rifampicin | |
| rpoC | 766978 | c.3609C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 767023 | c.3654C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767041 | c.3672G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 767044 | c.3675G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | c.3736_3738delAACinsCG | frameshift_variant&missense_variant | 0.99 | rifampicin | |
| rpoC | 767110 | c.3741T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767179 | c.3810C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767182 | c.3813G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767197 | c.3828G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767266 | c.3897G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767278 | c.3909T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767284 | c.3915C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767302 | c.3933C>G | synonymous_variant | 1.0 | rifampicin | |
| mmpL5 | 775856 | c.2625T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775865 | c.2616T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775874 | c.2607C>A | synonymous_variant | 0.36 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775881 | p.Asn867Arg | missense_variant | 0.64 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775883 | c.2596_2598delATCinsCG | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775886 | c.2595A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775901 | c.2580G>A | synonymous_variant | 0.64 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775904 | c.2577G>A | synonymous_variant | 0.36 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775909 | p.Leu858Phe | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775910 | c.2569_2571delCGGinsAA | frameshift_variant&missense_variant | 0.64 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775913 | c.2568C>G | synonymous_variant | 0.36 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775916 | c.2565T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775939 | p.Ala848Ser | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775940 | c.2541C>A | synonymous_variant | 0.64 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.73 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775946 | c.2535C>G | synonymous_variant | 0.75 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775961 | c.2520C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775971 | p.Ala837Val | missense_variant | 0.38 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775975 | c.2506T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775981 | p.Leu834Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775991 | p.Glu830Asp | missense_variant | 0.94 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775994 | c.2485_2487delATCinsCT | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775997 | c.2484T>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776000 | c.2481G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776005 | p.Ile826Leu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776009 | c.2472A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776027 | c.2454G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781592 | c.33T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781652 | c.93T>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781679 | c.120C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781742 | c.183C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 0.98 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 0.99 | streptomycin | Not assoc w R - Interim |
| rpsL | 781772 | c.213C>T | synonymous_variant | 0.99 | streptomycin | Not assoc w R - Interim |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781814 | c.255C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781827 | c.268C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781838 | c.279G>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 0.99 | streptomycin | Not assoc w R - Interim |
| rpsL | 781868 | c.309T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781877 | c.318T>A | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 0.98 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 0.98 | streptomycin | Uncertain significance |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800639 | c.-170C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800642 | c.-167C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800745 | c.-64_-62delCTCinsTG | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800931 | c.123G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800964 | c.156G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800967 | c.159C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 800985 | c.177A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801008 | p.Thr67Ser | missense_variant | 0.95 | linezolid | |
| rplC | 801012 | c.204T>C | synonymous_variant | 0.95 | linezolid | |
| rplC | 801019 | c.211_213delACCinsGG | frameshift_variant&missense_variant | 0.95 | linezolid | |
| rplC | 801027 | c.219C>G | synonymous_variant | 0.95 | linezolid | |
| rplC | 801030 | c.222C>A | synonymous_variant | 0.95 | linezolid | |
| rplC | 801039 | c.231A>G | synonymous_variant | 0.94 | linezolid | |
| rplC | 801045 | c.237A>G | synonymous_variant | 0.94 | linezolid | |
| rplC | 801046 | p.Tyr80His | missense_variant | 0.94 | linezolid | |
| rplC | 801054 | c.246G>C | synonymous_variant | 0.94 | linezolid | |
| rplC | 801063 | c.255G>T | synonymous_variant | 0.92 | linezolid | |
| rplC | 801147 | c.339T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801150 | c.342G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801153 | c.345G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801156 | c.348T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801171 | c.363A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801174 | c.366T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801207 | c.399C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801220 | p.Ser138Gly | missense_variant | 1.0 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801237 | c.429G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801249 | c.441T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801258 | c.450C>G | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303458 | c.528G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303464 | c.534A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303485 | c.555C>G | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303488 | c.558G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303492 | c.562T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303500 | c.570C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303536 | c.606G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303581 | c.651G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303611 | c.681G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303614 | c.684C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303629 | c.699C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303632 | c.702T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303638 | c.708A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303646 | p.Ala239Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304511 | c.1581C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304532 | c.1602G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304533 | c.1603T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304538 | c.1608C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304544 | c.1614T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304546 | p.Val539Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304556 | c.1626C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304562 | c.1632G>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304567 | p.Phe546Tyr | missense_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304604 | c.1674C>T | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304608 | p.Thr560Val | missense_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305348 | c.2418C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305381 | c.2451G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305393 | c.2463T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305399 | c.2469A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305405 | c.2475A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305418 | p.Val830Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305423 | c.2493T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364799 | c.387G>C | synonymous_variant | 0.88 | pyrazinamide | |
| sigE | 1364802 | c.390C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364818 | c.406_408delCTAinsTG | frameshift_variant&stop_gained | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364856 | c.444C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364859 | c.447C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364862 | c.450C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364865 | c.453G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364867 | p.Ala152Gly | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364872 | p.Ile154Val | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364877 | c.465G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364913 | c.501C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364926 | p.Asn172Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364949 | c.537C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364952 | c.540A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364960 | p.Gly183Asp | missense_variant | 0.96 | pyrazinamide | |
| sigE | 1364964 | c.552T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364976 | c.564T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364979 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364980 | c.568T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364984 | p.Ala191Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364992 | p.Pro194Ala | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1365003 | c.591T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365006 | c.594T>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365012 | c.600G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365018 | c.606G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365024 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365033 | c.621G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365042 | c.630G>C | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1461089 | c.45G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461097 | p.Ala18Gly | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461146 | c.102G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461153 | p.Ser37Ala | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| atpE | 1461159 | p.Val39Ile | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| atpE | 1461164 | c.120C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461167 | c.123G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461179 | c.135G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461182 | c.138A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461185 | c.141G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461188 | c.144G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461215 | c.171C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461224 | c.180T>C | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472019 | n.174G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472028 | n.183A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472030 | n.185G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472031 | n.186G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472033 | n.188A>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472035 | n.190G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472040 | n.195T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472042 | n.197T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472292 | n.447A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472298 | n.453G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472302 | n.457G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472305 | n.460_466delTTCTCTCinsATTTTTCTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472314 | n.469A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472431 | n.586G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472438 | n.593T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472683 | n.838_839insTA | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472848 | n.1003T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472859 | n.1014G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473100 | n.1255G>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473109 | n.1264T>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473111 | n.1266A>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473717 | n.60G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473746 | n.89T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473807 | n.150T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473811 | n.154C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473812 | n.155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473814 | n.157A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473815 | n.158T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473816 | n.159C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473887 | n.230delTinsAA | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473922 | n.265A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473923 | n.266C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473935 | n.278C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474026 | n.369C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474045 | n.388C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474083 | n.426C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474094 | n.437C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474100 | n.443C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474101 | n.444C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474106 | n.449_450delATinsGAC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474108 | n.451C>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1474110 | n.453A>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474263 | n.606G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474287 | n.630_648delTCCTTTTCCTCTCCGGAGGinsCTCTCTTGT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474350 | n.693G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474351 | n.694G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474452 | n.795C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474638 | n.981C>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474708 | n.1052dupG | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474711 | n.1054_1055insA | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474715 | n.1061delA | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475031 | n.1374G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475062 | n.1405A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475120 | n.1463G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475202 | n.1545G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475433 | n.1776A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475482 | n.1825A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475603 | n.1946G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475619 | n.1962C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475621 | n.1964T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475629 | n.1972_1973insC | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475762 | n.2105G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475764 | n.2107A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476095 | n.2438C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476103 | n.2446C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476108 | n.2451T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476246 | n.2589G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476262 | n.2605G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476665 | n.3008T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476679 | n.3022T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| fabG1 | 1674006 | p.Asp189Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674015 | c.-187C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674018 | c.-184G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674021 | c.-181G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674024 | c.-178T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674033 | c.-169T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674037 | p.Gln200Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674042 | c.-160G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674049 | c.610_612delCAAinsGC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674054 | c.-148T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674060 | c.-142A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674063 | c.-139G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674075 | c.-127C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674079 | p.Pro214Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674083 | p.Ala215Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674090 | c.-112C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674096 | c.-106G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674098 | p.Val220Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674114 | c.-88T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674123 | c.-79T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674126 | c.-76G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674127 | c.688_690delAGCinsGA | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674132 | c.-70T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674136 | p.Ser233Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674141 | c.-61T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674237 | c.36T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674239 | p.Ser13Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674243 | c.42A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674258 | c.57G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674261 | c.60G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674267 | c.66G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674279 | c.78A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674280 | p.Arg27Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674285 | c.84A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674295 | p.Gln32Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674303 | c.102C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674313 | p.Leu38Cys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674342 | c.141T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674348 | c.147C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674353 | p.Thr51Ile | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674443 | p.Ala81Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674450 | c.249G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674452 | p.Ala84Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674471 | c.270G>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674480 | c.279T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674483 | c.282G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674486 | c.285T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674489 | c.288G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674498 | c.297G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674507 | c.306G>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674514 | p.Ile105Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674519 | c.318C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674522 | c.321G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674550 | p.Ser117Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674570 | c.369G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674573 | c.372G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674576 | c.375T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674579 | c.378G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674600 | c.399G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674601 | p.Leu134Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674627 | c.426T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674639 | c.438C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674656 | p.Ser152Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674669 | c.468G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674702 | c.501G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674708 | c.507G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674876 | c.675C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674892 | p.Asn231Asp | missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674915 | c.714C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674927 | c.726G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674937 | p.Leu246Met | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674942 | c.741T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674954 | c.753G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674957 | c.756G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674963 | c.762G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674965 | c.765delT | frameshift_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674969 | c.768_769insG | frameshift_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674973 | p.Ile258Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674993 | c.792G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833540 | c.-2_-1delATinsC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833547 | c.6G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833596 | p.Ser19Ala | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833709 | c.168C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833763 | c.222C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833770 | p.Asn77His | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833778 | c.237C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833781 | c.240T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833805 | c.264C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833814 | c.273C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833820 | c.279G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833835 | c.294C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833859 | c.318C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833970 | c.429G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833988 | c.447C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834018 | c.477C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834024 | c.483G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834051 | c.510G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834108 | c.567C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834172 | p.Ile211Val | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834231 | c.690T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834354 | c.813G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834361 | c.820T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834408 | c.867C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834432 | c.891G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834522 | c.981C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834527 | p.Arg329His | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834573 | c.1032G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834603 | p.Glu354Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834666 | c.1125G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | p.Glu399Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834747 | c.1206A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834751 | c.1210_1212delCTTinsAC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834829 | p.Ala430Thr | missense_variant | 1.0 | pyrazinamide | |
| kasA | 2517917 | c.-198G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517926 | c.-189G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517965 | c.-150C>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517994 | c.-121C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518261 | c.147G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518268 | p.Thr52Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518525 | c.411G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518564 | c.450C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518570 | c.456G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518579 | c.465T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518594 | c.480C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518606 | c.492G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518618 | c.504G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518636 | c.522C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518688 | p.Val192Phe | missense_variant | 1.0 | isoniazid | |
| kasA | 2518693 | c.579C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518715 | p.Pro201Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2518727 | c.613C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518739 | p.Ala209Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518756 | c.642G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518759 | c.645C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518774 | c.660C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518780 | p.Glu222Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518787 | c.673_675delCGGinsGC | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518816 | c.702C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518834 | c.720C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518843 | c.729T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518853 | p.Leu247Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518867 | c.753G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518879 | c.765A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518898 | c.784T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518907 | c.793T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518910 | p.Leu266Met | missense_variant | 1.0 | isoniazid | |
| kasA | 2518915 | c.801T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519137 | c.1023T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519152 | c.1038G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519158 | c.1044C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519170 | c.1056G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519183 | c.1069_1071delCTCinsTG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2519194 | c.1080G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519195 | p.Thr361Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2519203 | c.1089C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519209 | c.1095C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519221 | c.1107G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519224 | c.1110C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726582 | c.390G>T | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726591 | c.399C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726593 | p.Val134Ala | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726600 | c.408T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726604 | p.Val138Ile | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726624 | c.432C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726638 | p.Ala149Val | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726645 | c.453C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726657 | c.465A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726669 | c.477T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726675 | c.483A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726681 | c.489A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726693 | c.501C>A | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726696 | c.504C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726717 | c.525A>C | synonymous_variant | 1.0 | isoniazid | |
| folC | 2747059 | c.540T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747062 | c.537A>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747065 | c.534C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747074 | c.525G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747080 | c.519C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747086 | c.513A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747089 | c.510G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747098 | c.501C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747101 | c.498G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747107 | c.492G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747110 | c.489T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747129 | p.Ala157Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747161 | c.438C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782501 | c.1542T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782531 | c.1512C>G | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782534 | c.1509C>T | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782537 | c.1506T>G | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782549 | c.1494T>C | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782555 | c.1486_1488delTCGinsAGC | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782558 | c.1485T>C | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782606 | c.1437T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782609 | c.1434G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782612 | c.1431T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782624 | c.1419G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782633 | c.1410G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782639 | c.1404A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782645 | c.1398C>G | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782651 | c.1392T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782669 | c.1374A>G | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783290 | c.753G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783302 | c.741A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783344 | c.699C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783347 | c.696C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783356 | c.687C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783364 | c.679C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783371 | c.670_672delGAAinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783377 | c.666C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783380 | c.663C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783386 | c.657G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783413 | c.630G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783425 | c.618C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783432 | c.610_611delAGinsTC | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783446 | c.597A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783455 | p.Gln196Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783516 | c.526_527delTCinsAG | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783545 | c.498C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783554 | c.489C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783563 | c.480A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783568 | p.Asn159His | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783575 | c.468G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783584 | c.457_459delGCCinsCG | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783617 | c.426G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783629 | c.414C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783634 | p.Leu137Ile | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783641 | c.402G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783651 | p.His131Ala | missense_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783659 | c.384A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783668 | c.375G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783672 | p.Arg124Lys | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783691 | c.352C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783692 | c.351G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783695 | c.348C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783908 | c.135G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783926 | c.117C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783935 | c.108C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783944 | c.99G>A | synonymous_variant | 0.98 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783963 | p.Ser27Asn | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783967 | c.76T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783974 | c.69C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783986 | c.57G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783989 | c.54G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2784001 | c.42G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784010 | c.33C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784047 | c.-5G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| pepQ | 2859735 | c.684G>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859738 | c.681C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859765 | c.654G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859771 | c.648T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859778 | p.Val214Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859780 | p.Gln213Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859786 | c.633G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859789 | c.630G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859792 | c.627C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859798 | c.621G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859813 | c.606C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859822 | c.597T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859827 | p.Ala198Pro | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859828 | c.591G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859831 | c.588C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859834 | c.585T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| pepQ | 2859852 | c.567A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| thyX | 3067328 | c.618G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067331 | c.615C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067349 | c.597G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067364 | c.582C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067405 | p.Thr181Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067406 | c.540A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067409 | c.537C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067424 | c.522G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067430 | c.516C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067433 | c.513C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067442 | c.504C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067829 | c.117C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067838 | c.108C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067844 | c.102G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067847 | p.Pro33Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067853 | c.93C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067869 | p.Thr26Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067883 | c.63C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067884 | c.60_61delAC | frameshift_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067888 | p.Pro20Ala | missense_variant | 0.86 | para-aminosalicylic_acid | |
| thyX | 3067892 | p.Leu18Phe | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067894 | c.51_52insAC | frameshift_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067898 | p.Asp16Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067910 | c.36C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073863 | c.609T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073878 | p.Glu198Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073887 | p.Ser195Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073892 | c.580T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073893 | c.579C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073902 | c.570C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073920 | c.552C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073932 | c.540C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073980 | c.492C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073992 | c.478_480delAGCinsTCT | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073999 | p.Arg158Lys | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074013 | c.459C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074022 | c.450C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074025 | c.445_447delTTCinsCG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074042 | p.Pro144Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3624356 | c.555C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624362 | c.549G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624377 | c.534C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624383 | c.528C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624389 | c.522C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624396 | p.Ala172Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624404 | c.507G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624407 | c.504C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624422 | c.489G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624425 | p.Glu162Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624428 | c.483A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624448 | c.463C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624449 | c.462C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624452 | c.459T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624464 | c.447A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624467 | c.444C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624470 | c.441T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625027 | c.-117C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Not assoc w R | |||||
| lpqB | 3625069 | c.-159T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625072 | c.-162G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625075 | c.-165G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625087 | c.-177C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625090 | c.-180C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625095 | p.Glu507Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625099 | c.-189C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625111 | c.-201G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625135 | c.-225A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625147 | c.-237C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625162 | c.-252T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625174 | c.-264C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625180 | c.-270C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625186 | c.-276T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625189 | c.1425A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625204 | c.1408_1410delTCGinsGC | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625207 | c.-297C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625231 | c.-321G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625251 | c.-341C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625255 | c.-345T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625261 | c.1351_1353delTACinsCT | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625291 | p.Glu441Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625294 | c.-384C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625306 | c.-396G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625313 | p.Arg434Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625321 | p.Lys431Arg | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625324 | p.His430Arg | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625327 | c.-417A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625336 | c.-426C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625351 | c.1263T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625357 | c.-447T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625369 | c.-459G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625375 | c.-465A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625381 | c.-471T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625386 | p.Ala410Pro | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625591 | c.-681C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625599 | p.Met339Leu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625623 | p.Thr331Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625627 | p.Asp329Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625630 | c.-720C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625633 | c.981C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625636 | c.-726C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625639 | c.-729C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625645 | c.969C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625648 | c.964_966delTATinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625660 | c.954C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625684 | c.-774G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625708 | c.906C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625720 | c.-810G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625747 | c.-837G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625761 | p.Gln285Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625765 | c.-855C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625819 | c.795G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625837 | c.-927C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625867 | c.747A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625879 | c.735G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625882 | c.-972G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625899 | p.Val239Leu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626696 | c.-83T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626699 | c.-86C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626731 | p.Lys207Gln | missense_variant | 0.97 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626735 | c.-122C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626776 | c.-163A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626777 | c.573C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626789 | c.561C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626804 | c.-191A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626816 | c.-203G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626822 | p.Asp176Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626882 | c.468G>C | synonymous_variant | 0.83 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.85 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626891 | c.-278G>C | upstream_gene_variant | 0.86 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.79 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626907 | p.Asn148Ala | missense_variant | 0.86 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626909 | c.441C>G | synonymous_variant | 0.86 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626913 | p.Thr146Ser | missense_variant | 0.88 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626915 | c.-302C>G | upstream_gene_variant | 0.89 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626942 | c.406_408delGTAinsAC | frameshift_variant&missense_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 0.97 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626996 | c.-383G>C | upstream_gene_variant | 0.99 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627050 | c.300C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627068 | c.282T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627125 | c.-512C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627131 | p.Ala73Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627134 | c.-521C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627146 | c.204C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627149 | c.-536G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| fbiA | 3640701 | p.Ile53Met | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640707 | c.-828G>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640708 | p.Leu56Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640713 | c.-822T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640714 | p.Val58Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640725 | c.-810T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640728 | c.-807G>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640743 | c.-792T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640755 | c.-780C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640758 | c.-777G>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640764 | c.-771C>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640768 | p.Gln76Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640785 | p.Gln81His | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640788 | c.-747T>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642550 | p.Gln339Arg | missense_variant | 1.0 | clofazimine | Uncertain significance |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fbiB | 3642560 | c.1026T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642588 | p.Leu352Met | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642593 | c.1059G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642609 | p.Ser359His | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642620 | c.1086T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642623 | c.1089C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642625 | p.Ala364Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642629 | c.1095C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642634 | p.Asp367Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642659 | c.1125C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rpoA | 3877473 | c.1035A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877503 | p.Ala335Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877507 | p.Gly334Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877509 | p.Glu333Asp | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877514 | p.Thr332Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877533 | c.975C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877542 | c.966C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877545 | c.963G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877548 | c.960C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877553 | p.Glu319Gln | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877569 | c.937_939delCCGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoA | 3877572 | c.936G>T | synonymous_variant | 0.99 | rifampicin | |
| rpoA | 3877584 | c.924C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877596 | c.912G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 0.99 | rifampicin | |
| rpoA | 3877677 | c.831G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877680 | c.828G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877683 | c.825G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877689 | c.819C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877695 | c.813C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877710 | c.798C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877740 | c.768G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877773 | c.735G>T | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877788 | c.720G>A | synonymous_variant | 0.99 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877856 | c.652T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877872 | c.636C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877881 | c.627G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877908 | c.600T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877929 | c.577_579delATCinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877974 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878166 | c.342C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878175 | c.333G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878197 | p.Glu104Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878244 | c.264G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878250 | c.258C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878253 | c.255G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878276 | c.232C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878301 | c.207C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878310 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878394 | c.114G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878400 | c.108T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878421 | c.87A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878424 | c.84G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878433 | c.75G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878451 | c.57C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878454 | c.54A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878460 | p.Asp16Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878465 | p.Thr15Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878468 | p.Leu14Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878475 | c.33G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878487 | c.21C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878490 | c.18C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878672 | c.-165A>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878698 | c.-191A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878701 | c.-194C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878705 | c.-198A>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878713 | c.-206G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878725 | c.-220_-218delCTAinsTG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878734 | c.-229_-227delATCinsGT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878758 | c.-251G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878775 | c.-268A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878796 | c.-289G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878797 | c.-290G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878806 | c.-299C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878830 | c.-325_-323delCTGinsAC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878843 | c.-337_-336delCGinsAA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878845 | c.-338G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878873 | c.-366G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.97 | rifampicin | Uncertain significance |
| rpoA | 3878884 | c.-377C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878893 | c.-388_-386delCACinsAG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878899 | c.-392C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878947 | c.-440G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878956 | c.-449G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878961 | c.-454C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878962 | c.-455G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878974 | c.-469_-467delATCinsGT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878977 | c.-470C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879049 | c.-542A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879061 | c.-554C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879070 | c.-563G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879073 | c.-566A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879097 | c.-590C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879124 | c.-618_-617delTGinsGC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879178 | c.-671T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879190 | c.-683C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879199 | c.-692C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879207 | c.-700G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879208 | c.-701C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879215 | c.-709_-708delACinsGT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879219 | c.-712C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879223 | c.-716G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879229 | c.-722A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986621 | c.-223G>C | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986633 | c.-211C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986661 | c.-183C>A | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986664 | c.-180_-179delAGinsTC | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986672 | c.-172G>A | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986696 | c.-148G>A | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986699 | c.-145C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4038290 | p.Asp805Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038293 | c.2412G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038296 | c.2409C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038310 | p.Val799Leu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038314 | c.2391T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038317 | c.2388G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038320 | c.2385G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038325 | p.Val794Leu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038329 | c.2376G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038335 | c.2370C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038395 | c.2310C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038416 | c.2289C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038509 | c.2196C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038519 | p.Arg729Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | c.2175G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038533 | p.Arg724Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038539 | c.2166G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038563 | c.2142C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038605 | c.2100G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038620 | p.Gln695Leu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038647 | c.2058T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038668 | c.2037G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038677 | c.2026_2028delCCGinsGC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038692 | c.2013C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038722 | c.1983G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038726 | p.Thr660Cys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038809 | p.Gln632Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038838 | c.1867C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038842 | c.1863G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038863 | c.1842G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038905 | c.1800A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038962 | c.1743C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039001 | c.1702_1704delAACinsGG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039034 | c.1671C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039073 | c.1632C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039090 | c.1615C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039139 | c.1566G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039187 | c.1518G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039235 | c.1470C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039265 | c.1440C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039277 | c.1428C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039280 | c.1425G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039286 | c.1417_1419delCTTinsTG | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039304 | c.1401G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039310 | c.1395A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039358 | c.1347C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039364 | c.1341C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039385 | c.1320C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039406 | c.1299G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039448 | c.1257A>G | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039454 | c.1251A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039484 | c.1221T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039568 | p.Met379Ile | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039571 | c.1134G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039576 | p.Ala377Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039581 | p.Thr375Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039601 | c.1104G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039652 | c.1053G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039655 | c.1050G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039658 | c.1047G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039736 | c.969C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039742 | c.963C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039763 | c.942C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039841 | c.864G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039855 | c.850C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039889 | c.816G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039942 | c.763C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039997 | c.708C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040001 | p.His235Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040009 | c.696C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040020 | c.685C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040027 | c.678C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040030 | c.675C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040042 | c.663C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040057 | c.648C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040090 | c.615T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040135 | c.570C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040144 | c.561G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040159 | c.546G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040165 | c.540G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040168 | c.537G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040204 | c.501G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040213 | c.492T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040216 | c.489C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040221 | p.Ser162Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040231 | c.474C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040234 | c.471C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040257 | p.Ala150Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040288 | c.417C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040300 | c.405C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040309 | c.396C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040315 | p.Glu130Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040318 | c.387C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040321 | c.384C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040336 | c.369G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>A | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040435 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040441 | c.264C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040444 | c.261C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040462 | c.243C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040501 | c.204C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040513 | c.192G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040552 | c.153G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040561 | c.144A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040600 | c.103_105delTTAinsCT | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040618 | c.87C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040654 | c.51G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040669 | c.36C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040695 | c.10C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040708 | c.-4A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044024 | c.258T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044036 | c.246G>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044039 | c.243G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044045 | c.237G>A | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044050 | c.232T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044051 | c.231C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044057 | c.225C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044060 | c.222C>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044072 | c.210C>A | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044075 | c.207T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044096 | c.186C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044108 | c.174C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044114 | c.168C>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044120 | c.162A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044123 | c.159T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044126 | c.156T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044138 | c.144T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044147 | c.135C>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044150 | c.132A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044156 | c.126A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044162 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044165 | c.117G>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044177 | c.105C>T | synonymous_variant | 1.0 | pyrazinamide | |
| glpK | 4138535 | c.1221T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138541 | c.1215C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138583 | c.1173G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138586 | c.1170C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138610 | c.1146C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138625 | c.1131G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138628 | c.1128T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138631 | c.1125C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138646 | c.1110G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138655 | c.1101G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138661 | c.1095T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138667 | c.1089G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138682 | c.1074C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138696 | p.Pro354Ser | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138712 | c.1042_1044delGCGinsAT | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138718 | p.Ser346Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138724 | c.1030_1032delGCAinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138751 | c.1005T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.997_999delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138769 | c.987G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138775 | c.981C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138781 | c.975G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138793 | c.963T>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240717 | c.855T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240723 | c.861C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240756 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240759 | c.897C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240769 | c.907_909delGTGinsAT | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240786 | c.924C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240800 | p.Tyr313Phe | missense_variant | 1.0 | ethambutol | |
| embC | 4240807 | c.945C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240819 | c.957A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240822 | c.960C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240855 | c.993G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240996 | c.1134G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241002 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241024 | p.Val388Phe | missense_variant | 1.0 | ethambutol | |
| embC | 4241035 | c.1173G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241039 | p.Asp393Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4241044 | c.1182C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241047 | c.1185C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241053 | c.1191G>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241077 | c.1215C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241084 | p.Leu408Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4241110 | c.1248G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241125 | c.1263G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241135 | p.Val425Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | p.Leu434Met | missense_variant | 1.0 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241182 | c.1320G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241185 | c.1323G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241188 | c.1326C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241206 | c.1344G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242826 | c.-407G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242862 | c.-371A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242863 | p.Tyr1001Asn | missense_variant | 1.0 | ethambutol | |
| embA | 4242868 | c.-365C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242871 | c.-362C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242872 | p.Asp1004Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4242878 | p.Thr1006Val | missense_variant | 1.0 | ethambutol | |
| embC | 4242904 | c.3042C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4242916 | c.-317C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242919 | c.-314A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242928 | c.-305A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4247404 | c.891G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247407 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247420 | p.Ile303Val | missense_variant | 1.0 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247428 | c.915C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247434 | c.921C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247437 | c.924A>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247449 | c.936C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247462 | c.949_950delTCinsAG | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247494 | c.981G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247527 | c.1014G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247528 | c.1015C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248133 | c.1620C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248139 | c.1626C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248149 | p.Thr546Cys | missense_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248173 | p.Val554Met | missense_variant | 1.0 | ethambutol | |
| embB | 4248190 | c.1677G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248199 | c.1686A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248203 | p.Pro564Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248211 | c.1698G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248215 | p.Arg568Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248225 | p.Ala571Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248250 | p.Phe579Leu | missense_variant | 1.0 | ethambutol | |
| embB | 4248252 | p.Gly580Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248264 | p.Phe584Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248275 | p.Thr588Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248295 | c.1782C>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268063 | c.772_774delTCGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4268068 | p.Val257Leu | missense_variant | 1.0 | ethambutol | |
| aftB | 4268081 | c.756A>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268099 | c.738G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268105 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268120 | c.717C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268123 | c.712_714delAGTinsGC | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4268129 | c.708T>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268138 | c.699A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268144 | c.693T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268444 | c.393C>G | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
| aftB | 4268447 | c.390G>C | synonymous_variant | 0.9 | ethambutol | |
| aftB | 4268450 | c.387A>G | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
| aftB | 4268455 | p.Val128Leu | missense_variant | 0.9 | ethambutol | |
| aftB | 4268462 | c.375T>C | synonymous_variant | 0.9 | ethambutol | |
| aftB | 4268465 | c.372A>C | synonymous_variant | 0.9 | ethambutol |
