TB-Profiler result

Run: ERR1063856

Summary

Run ID: ERR1063856

Sample name:

Date: 2024-04-14T01:57:09.480693

Number of reads: 1668627

Percentage reads mapped: 18.66

Median coverage: 11.0

Strain: M.canetti;lineage4.9;lineage9

Spoligotype:

Drug-resistance: HR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.1.2 Indo-Oceanic RD239 0.17
lineage9 Lineage 9 None 0.35
lineage2.2.2 East-Asian (Beijing) RD105;RD207 0.22
lineage4 Euro-American None 0.75
lineage4.2.1.1 Euro-American (TUR) None 0.13
lineage4.9 Euro-American (H37Rv-like) None 0.61
M.canetti M.canetti None 0.07
lineage5.1.4 West-Africa 1 RD711 0.28
lineage4.6.2.1 Euro-American RD726 0.24
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
kasA p.Arg121Lys Mutation from literature
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.592_594delGCCinsCG Assoc w R - Interim
c.541_543delCTCinsGT Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.280_282delGGAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.760_762delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.766_768delGCTinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.889_891delGTAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1105_1107delCGGinsAA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1825_1827delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.82_84delGATinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.97_99delGTCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.157_159delGTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.592_594delGCCinsCG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.541_543delCTCinsGT Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491062 c.280_282delGGAinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491542 c.760_762delTTGinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491548 c.766_768delGCTinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491671 c.889_891delGTAinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304035 c.1105_1107delCGGinsAA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304755 c.1825_1827delCTAinsTG frameshift_variant&stop_gained 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
kasA 2518476 p.Arg121Lys missense_variant 1.0 isoniazid Mutation from literature
pepQ 2859825 c.592_594delGCCinsCG frameshift_variant&synonymous_variant 0.98 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
pepQ 2859876 c.541_543delCTCinsGT frameshift_variant&missense_variant 1.0 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
fbiB 3641616 c.82_84delGATinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641631 c.97_99delGTCinsAT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641691 c.157_159delGTGinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 762 c.762C>T synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.97 isoniazid
dnaA 780 c.780C>G synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 819 c.819C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877_879delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 888 c.888C>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>G synonymous_variant 1.0 isoniazid
dnaA 912 c.912T>C synonymous_variant 1.0 isoniazid
dnaA 915 c.915C>T synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 969 c.969G>A synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>T synonymous_variant 1.0 isoniazid
dnaA 993 c.993A>G synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>T synonymous_variant 1.0 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 1.0 isoniazid
dnaA 1041 c.1041G>A synonymous_variant 1.0 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 1.0 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 1.0 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1056 c.1056G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>T synonymous_variant 1.0 isoniazid
dnaA 1062 c.1062C>T synonymous_variant 1.0 isoniazid
dnaA 1068 p.Asp356Glu missense_variant 1.0 isoniazid Uncertain significance
dnaA 1071 c.1071C>A synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 1.0 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1134 c.1134G>A synonymous_variant 1.0 isoniazid
dnaA 1143 c.1143G>T synonymous_variant 1.0 isoniazid
dnaA 1149 c.1149C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1204 c.1204C>T synonymous_variant 0.99 isoniazid
dnaA 1209 c.1209C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>G synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1308 c.1308G>A synonymous_variant 1.0 isoniazid
gyrB 6056 p.Ser273Gly missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6067 c.828G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6085 c.846C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6094 c.855C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6201 c.963delC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6205 c.967dupG frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6274 c.1035C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6373 c.-929C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6577 c.-725T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6595 c.1356G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6598 c.-704C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6664 c.1425C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6748 c.-554G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6881 c.1642T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6961 c.-341G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7018 c.-284G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7190 c.-112C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7204 c.-98C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7412 c.111C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7758 p.Ile153Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 7802 c.501C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7818 c.517C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7844 c.543C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7881 c.580C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7923 p.His208Phe missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8071 p.Val257Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8076 p.Val259Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8106 c.805C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8111 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8117 c.816C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8337 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8435 c.1134C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8498 c.1197C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8580 p.Ile427Val missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8588 c.1287G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8637 c.1336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8684 c.1383G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8690 c.1389C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8702 c.1401C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8706 c.1405C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8843 c.1542G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9059 c.1758G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9110 c.1809G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9125 c.1824C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 c.1846_1848delGGCinsAT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9188 p.Asn629Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9204 c.1903_1905delTCCinsAG frameshift_variant&synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9291 c.1990_1992delCTGinsTA frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9329 c.2028C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9369 c.2068C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9389 c.2088C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9398 c.2097T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9621 p.Leu774Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9625 p.Tyr775Phe missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9653 c.2352C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9662 c.2361G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9665 c.2364A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9680 c.2379G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9746 c.2445C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 490794 c.12G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490803 c.21T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490809 c.27A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490824 c.42A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490839 c.57G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490853 p.Ala24Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490857 c.75C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490950 c.168C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491109 c.327G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491113 c.331C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491223 c.441C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491229 c.447C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491256 c.474G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491268 c.486C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491379 c.597C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491453 p.Gly224Asp missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 p.Glu240Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491556 c.774G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491605 c.823C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491688 c.906A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491694 c.912C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491703 c.921C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491712 c.930T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491718 c.936A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491721 c.939A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491727 c.945T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491730 c.948C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491751 c.969C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575641 c.294A>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575665 c.318G>T synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
mshA 575668 c.321G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575716 c.369C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575725 c.378C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575905 c.558G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
ccsA 620569 c.679_681delGGAinsCC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620597 p.Ala236Gly missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620647 c.757_759delGAAinsCG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656058 c.1413C>T synonymous_variant 1.0 ethionamide
Rv0565c 656061 c.1408_1410delATCinsCG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656073 p.Leu466Phe missense_variant 1.0 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 1.0 ethionamide
Rv0565c 656085 c.1386A>T synonymous_variant 1.0 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 1.0 ethionamide
Rv0565c 656112 c.1359C>G synonymous_variant 1.0 ethionamide
Rv0565c 656124 c.1347G>C synonymous_variant 0.98 ethionamide
Rv0565c 656127 c.1342_1344delTACinsCT frameshift_variant&missense_variant 0.98 ethionamide Uncertain significance
Rv0565c 656131 p.Pro447Leu missense_variant 0.98 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 0.98 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 0.98 ethionamide
Rv0565c 656145 c.1326T>C synonymous_variant 0.98 ethionamide
Rv0565c 656157 c.1314T>C synonymous_variant 0.98 ethionamide
Rv0565c 656172 c.1299A>G synonymous_variant 0.98 ethionamide
Rv0565c 656179 p.Asp431Pro missense_variant 0.97 ethionamide
Rv0565c 656188 p.Glu428Gly missense_variant 0.97 ethionamide
Rv0565c 656191 p.Asp427Gly missense_variant 0.97 ethionamide
Rv0565c 656199 c.1272C>T synonymous_variant 0.96 ethionamide
Rv0565c 657563 c.-93T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657590 c.-120G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657593 c.-123G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657598 c.-128C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657640 c.-170A>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsTC upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731685 c.-245C>G upstream_gene_variant 1.0 isoniazid
hadA 731687 c.-243G>C upstream_gene_variant 1.0 isoniazid
hadA 731688 c.-242C>A upstream_gene_variant 1.0 isoniazid
hadA 731691 c.-239G>C upstream_gene_variant 1.0 isoniazid
hadA 731694 c.-236T>G upstream_gene_variant 1.0 isoniazid
hadA 731695 c.-235C>G upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 1.0 isoniazid
hadA 731700 c.-230G>A upstream_gene_variant 1.0 isoniazid
hadA 731708 c.-222G>T upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731712 c.-218A>G upstream_gene_variant 1.0 isoniazid
hadA 731726 c.-204C>T upstream_gene_variant 1.0 isoniazid
hadA 731732 c.-198G>C upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 1.0 isoniazid
hadA 731817 c.-113C>A upstream_gene_variant 1.0 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 1.0 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 731855 c.-75C>T upstream_gene_variant 1.0 isoniazid
hadA 731861 c.-69G>T upstream_gene_variant 1.0 isoniazid
hadA 731864 c.-66C>T upstream_gene_variant 1.0 isoniazid
nusG 734053 c.-201A>T upstream_gene_variant 1.0 rifampicin
nusG 734063 c.-191C>G upstream_gene_variant 1.0 rifampicin
nusG 734066 c.-188G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734072 c.-182C>A upstream_gene_variant 1.0 rifampicin
nusG 734075 c.-179T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734077 c.-177C>G upstream_gene_variant 1.0 rifampicin
nusG 734082 c.-172A>C upstream_gene_variant 1.0 rifampicin
nusG 734087 c.-167G>C upstream_gene_variant 1.0 rifampicin
nusG 734093 c.-161A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 1.0 rifampicin
nusG 734118 c.-136_-134delCTTinsAC upstream_gene_variant 1.0 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 1.0 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734152 c.-102_-101delCCinsTG upstream_gene_variant 1.0 rifampicin
nusG 734384 p.Ser44Thr missense_variant 1.0 rifampicin
nusG 734388 c.135G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734391 c.138C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734403 c.150C>T synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734614 c.361_363delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734631 c.378G>C synonymous_variant 1.0 rifampicin
nusG 734634 c.381G>C synonymous_variant 1.0 rifampicin
nusG 734811 c.558G>A synonymous_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.97 rifampicin
nusG 734832 c.579C>G synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.97 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734889 c.636G>A synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
rpoB 759571 c.-236C>A upstream_gene_variant 1.0 rifampicin
rpoB 759604 c.-203A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759606 c.-201T>C upstream_gene_variant 1.0 rifampicin
rpoB 759616 c.-191C>T upstream_gene_variant 1.0 rifampicin
rpoB 759643 c.-164T>C upstream_gene_variant 1.0 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759656 c.-150delG upstream_gene_variant 1.0 rifampicin
rpoB 759661 c.-146G>C upstream_gene_variant 1.0 rifampicin
rpoB 759672 c.-135G>A upstream_gene_variant 1.0 rifampicin
rpoB 759674 c.-133T>C upstream_gene_variant 1.0 rifampicin
rpoB 759690 c.-116delA upstream_gene_variant 1.0 rifampicin
rpoB 759694 c.-113C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759701 c.-106A>T upstream_gene_variant 1.0 rifampicin
rpoB 759706 c.-101T>C upstream_gene_variant 1.0 rifampicin
rpoB 759711 c.-96G>A upstream_gene_variant 1.0 rifampicin
rpoB 759715 c.-91delA upstream_gene_variant 1.0 rifampicin
rpoB 759725 c.-82A>C upstream_gene_variant 1.0 rifampicin
rpoB 759727 c.-80A>G upstream_gene_variant 1.0 rifampicin
rpoB 760052 c.246G>A synonymous_variant 1.0 rifampicin
rpoB 760059 c.253_255delTACinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>G synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760185 c.379C>T synonymous_variant 1.0 rifampicin
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760325 c.519G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>C synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760422 c.616_618delCTCinsTG frameshift_variant&missense_variant 0.99 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760521 p.Ser239Ala missense_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760568 c.762G>C synonymous_variant 1.0 rifampicin
rpoB 760571 c.765G>C synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760597 p.Thr264Ser missense_variant 1.0 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760643 c.837G>A synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>A synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>G synonymous_variant 1.0 rifampicin
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760727 c.921C>A synonymous_variant 1.0 rifampicin
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.99 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.99 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761124 c.1318C>T synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 1.0 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 1.0 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761217 c.1411_1413delCCGinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761289 p.Ser495Ala missense_variant 1.0 rifampicin
rpoB 761303 c.1497G>A synonymous_variant 1.0 rifampicin
rpoB 761306 c.1500C>G synonymous_variant 1.0 rifampicin
rpoB 761309 c.1503C>T synonymous_variant 1.0 rifampicin
rpoB 761315 c.1509C>T synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761346 p.Val514Arg missense_variant 1.0 rifampicin
rpoB 761354 c.1548C>G synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>G synonymous_variant 1.0 rifampicin
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761369 p.Glu521Asp missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761411 c.1605G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.95 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 0.96 rifampicin
rpoB 761482 p.Ala559Gly missense_variant 0.97 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.98 rifampicin
rpoB 761502 c.1696_1698delCCCinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoB 761508 c.1702_1704delTCTinsGC frameshift_variant&missense_variant 0.98 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 1.0 rifampicin
rpoB 761532 p.Ser576Ala missense_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761655 p.Ala617Arg missense_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.99 rifampicin
rpoB 761734 p.Val643Ala missense_variant 0.99 rifampicin
rpoB 761738 c.1932C>T synonymous_variant 0.99 rifampicin
rpoB 761744 c.1938G>A synonymous_variant 0.99 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.99 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.99 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.99 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.99 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.99 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.99 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761894 c.2088C>T synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761908 p.Cys701Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761916 c.2110_2112delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761931 c.2125C>T synonymous_variant 1.0 rifampicin
rpoB 761951 c.2145G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 1.0 rifampicin
rpoB 762251 c.2445G>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.99 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762348 c.2542_2543delTCinsAG synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 1.0 rifampicin
rpoC 762390 c.-980C>T upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762489 p.Val895Gln missense_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.99 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 762521 c.-849C>A upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 1.0 rifampicin
rpoC 762605 c.-765T>C upstream_gene_variant 1.0 rifampicin
rpoC 762710 c.-660G>T upstream_gene_variant 1.0 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 1.0 rifampicin
rpoC 762734 c.-636G>A upstream_gene_variant 1.0 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 1.0 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 1.0 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762791 c.-579G>C upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.96 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763220 c.-150G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.96 rifampicin
rpoC 763262 c.-108C>G upstream_gene_variant 0.95 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.98 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 1.0 rifampicin
rpoC 763304 c.-66A>C upstream_gene_variant 1.0 rifampicin
rpoC 763305 c.-65_-64delAGinsTC upstream_gene_variant 1.0 rifampicin
rpoC 763310 c.-60C>T upstream_gene_variant 1.0 rifampicin
rpoC 763322 c.-48G>A upstream_gene_variant 1.0 rifampicin
rpoC 763325 c.-45_-44insATC upstream_gene_variant 1.0 rifampicin
rpoC 763329 c.-40_-34delGTCGCAA upstream_gene_variant 1.0 rifampicin
rpoC 763338 c.-32A>G upstream_gene_variant 1.0 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763453 c.84C>A synonymous_variant 1.0 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>A synonymous_variant 1.0 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763727 c.358C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Gly missense_variant 1.0 rifampicin
rpoC 763796 p.Met143Leu missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763867 c.498C>G synonymous_variant 1.0 rifampicin
rpoC 763871 p.Gly168Ser missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763885 c.516C>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 1.0 rifampicin
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>T synonymous_variant 1.0 rifampicin
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764095 c.726C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764134 c.765C>A synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764191 c.822C>T synonymous_variant 1.0 rifampicin
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764212 c.843C>T synonymous_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764269 c.900G>A synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 1.0 rifampicin
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764392 c.1023C>T synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764437 c.1068G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.94 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>C synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764614 c.1245G>A synonymous_variant 1.0 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.99 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764659 c.1290C>T synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.99 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>G synonymous_variant 0.99 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.99 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764854 c.1485G>C synonymous_variant 0.99 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765005 c.1637_1638insGC frameshift_variant 1.0 rifampicin
rpoC 765010 c.1641_1643delGAGinsC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.99 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765088 c.1719G>A synonymous_variant 0.98 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>T synonymous_variant 0.96 rifampicin
rpoC 765122 c.1753C>T synonymous_variant 0.96 rifampicin
rpoC 765145 c.1776C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765259 c.1890G>A synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765281 p.Thr638Glu missense_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765310 c.1941G>A synonymous_variant 1.0 rifampicin
rpoC 765313 c.1944C>T synonymous_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 c.1957_1959delCACinsGA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 0.97 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765346 c.1977C>A synonymous_variant 1.0 rifampicin
rpoC 765350 c.1981_1983delGCGinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765404 p.Leu679Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765451 c.2082C>G synonymous_variant 1.0 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765490 c.2121C>T synonymous_variant 1.0 rifampicin
rpoC 765493 c.2124G>C synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>A synonymous_variant 1.0 rifampicin
rpoC 765523 c.2154C>T synonymous_variant 1.0 rifampicin
rpoC 765547 c.2178C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2180delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765590 p.Arg741Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 765596 p.Lys743Gln missense_variant 1.0 rifampicin
rpoC 765611 p.His748Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765694 c.2325G>A synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>G synonymous_variant 1.0 rifampicin
rpoC 765733 c.2364G>T synonymous_variant 1.0 rifampicin
rpoC 765734 c.2365_2367delTTGinsCT frameshift_variant&synonymous_variant 0.99 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 1.0 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>G synonymous_variant 1.0 rifampicin
rpoC 765865 c.2496C>T synonymous_variant 0.99 rifampicin
rpoC 765871 c.2502T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765895 c.2526G>A synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.99 rifampicin
rpoC 765937 c.2568T>A synonymous_variant 1.0 rifampicin
rpoC 765946 c.2577C>G synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>A synonymous_variant 1.0 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766255 c.2886G>T synonymous_variant 1.0 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766276 c.2907C>G synonymous_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 1.0 rifampicin
rpoC 766297 c.2928G>C synonymous_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>A synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766351 c.2982C>G synonymous_variant 1.0 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 1.0 rifampicin
rpoC 766369 c.3000C>T synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.99 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766444 c.3075C>T synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766514 p.Val1049Ile missense_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766618 c.3249G>C synonymous_variant 1.0 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766652 p.Ser1095Thr missense_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 1.0 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.99 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766942 c.3573C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>A synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766966 c.3597G>A synonymous_variant 0.99 rifampicin
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>G synonymous_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 1.0 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767317 c.3949_*2629del stop_lost&conservative_inframe_deletion&splice_region_variant 1.0 rifampicin
mmpL5 775847 c.2634G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775880 c.2601C>T synonymous_variant 0.42 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775892 c.2589C>T synonymous_variant 0.37 clofazimine
bedaquiline
mmpL5 775895 c.2586C>T synonymous_variant 0.37 clofazimine
bedaquiline
mmpL5 775901 c.2580G>A synonymous_variant 0.57 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 0.37 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>G synonymous_variant 0.36 clofazimine
bedaquiline
mmpL5 775939 p.Ala848Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775940 c.2541C>G synonymous_variant 0.32 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775954 c.2527C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775961 c.2520C>G synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 775964 c.2515_2517delGCGinsTA frameshift_variant&missense_variant 0.3 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775975 c.2506T>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775990 c.2491C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776005 p.Ile826Val missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776008 p.His825Tyr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781164 c.-396T>C upstream_gene_variant 1.0 streptomycin
rpsL 781174 c.-386C>A upstream_gene_variant 1.0 streptomycin
rpsL 781179 c.-381T>C upstream_gene_variant 1.0 streptomycin
rpsL 781185 c.-375T>C upstream_gene_variant 1.0 streptomycin
rpsL 781189 c.-371T>C upstream_gene_variant 1.0 streptomycin
rpsL 781206 c.-354C>T upstream_gene_variant 1.0 streptomycin
rpsL 781208 c.-352T>C upstream_gene_variant 1.0 streptomycin
rpsL 781217 c.-343_-342insCAT upstream_gene_variant 1.0 streptomycin
rpsL 781224 c.-336T>C upstream_gene_variant 1.0 streptomycin
rpsL 781230 c.-330T>C upstream_gene_variant 1.0 streptomycin
rpsL 781231 c.-329_-327delGCGinsAC upstream_gene_variant 1.0 streptomycin
rpsL 781234 c.-326G>T upstream_gene_variant 1.0 streptomycin
rpsL 781240 c.-320A>T upstream_gene_variant 1.0 streptomycin
rpsL 781252 c.-308C>T upstream_gene_variant 1.0 streptomycin
rpsL 781257 c.-303G>C upstream_gene_variant 1.0 streptomycin
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781583 c.24C>G synonymous_variant 1.0 streptomycin
rpsL 781592 c.33T>A synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781643 c.84G>A synonymous_variant 1.0 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781664 c.105C>T synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>G synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>T synonymous_variant 1.0 streptomycin
rpsL 781724 c.165G>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>T synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>G synonymous_variant 1.0 streptomycin
rpsL 781805 c.246G>A synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781862 c.303G>A synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.99 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781919 c.360G>A synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800549 c.-260G>T upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800576 c.-233C>T upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 1.0 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>T upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800603 c.-206G>A upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800657 c.-152G>A upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800726 c.-83G>A upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800786 c.-23C>T upstream_gene_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64A>C synonymous_variant 1.0 linezolid
rplC 800877 c.69A>G synonymous_variant 1.0 linezolid
rplC 800880 c.72A>C synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800931 c.123G>T synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800940 c.132C>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800962 c.154C>T synonymous_variant 1.0 linezolid
rplC 800967 c.159C>T synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 800994 c.186C>G synonymous_variant 1.0 linezolid
rplC 801165 c.357G>A synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801168 c.360C>T synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801201 c.393C>T synonymous_variant 1.0 linezolid
rplC 801210 c.402T>G synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801216 c.408C>T synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801231 c.423C>G synonymous_variant 1.0 linezolid
rplC 801249 c.441T>C synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>T synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>A synonymous_variant 0.99 linezolid
rplC 801282 c.474G>A synonymous_variant 1.0 linezolid
rplC 801312 c.504G>T synonymous_variant 1.0 linezolid
rplC 801321 c.513C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801330 c.522G>A synonymous_variant 0.98 linezolid
rplC 801337 c.529_531delGTTinsAG frameshift_variant&missense_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801366 c.558T>C synonymous_variant 1.0 linezolid
rplC 801367 c.559_561delGCCinsAT frameshift_variant&missense_variant 0.97 linezolid
rplC 801372 p.Glu188Asp missense_variant 1.0 linezolid
rplC 801378 c.570C>T synonymous_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
Rv1129c 1253422 c.1113G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253431 c.1104C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253443 c.1092G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253470 c.1065C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253476 c.1059G>T synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253479 c.1056G>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253482 c.1053G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253485 c.1050C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253491 c.1044A>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253494 c.1041G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253509 c.1026C>T synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv1129c 1253512 c.1023G>A synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv1129c 1253521 c.1012_1014delCGCinsAG frameshift_variant&missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1254277 c.258C>A synonymous_variant 0.96 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254280 c.255G>A synonymous_variant 0.97 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254289 c.246A>C synonymous_variant 0.97 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254292 c.243C>T synonymous_variant 0.97 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254301 c.234G>C synonymous_variant 0.97 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254310 c.225T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254313 p.Gln74His missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1254318 p.Ala73Pro missense_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254319 c.214_216delTCGinsCA frameshift_variant&synonymous_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1254328 c.207T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254340 c.195T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254344 p.Leu64Ala missense_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254346 c.189T>G synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254355 c.180C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254379 c.156T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254385 c.148_150delTTGinsCC frameshift_variant&missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1254397 c.138T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254403 c.132A>G synonymous_variant 1.0 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv1129c 1254406 c.129C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254411 c.124T>C synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254412 c.123C>T synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254418 c.117C>G synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254422 p.Lys38Arg missense_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254430 c.105G>T synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1254433 c.102G>T synonymous_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
fbiC 1303419 c.489C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303425 c.495G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303428 c.498C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303431 c.501T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303440 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303441 p.Leu171Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303446 c.516C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303479 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303527 c.597G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303536 c.606G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303554 c.624G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303557 c.627G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303580 p.Thr217Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303629 c.699C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303645 p.Ala239Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303653 c.723G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303654 c.724C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303671 c.741C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303722 c.792C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 p.Asp272Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303768 p.Ser280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303824 c.894G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303827 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303938 c.1008C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303959 c.1029C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303965 c.1035G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303995 c.1065C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304004 c.1074A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304055 c.1125C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304061 c.1131G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304068 p.Val380Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304082 c.1152C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304098 p.Gln390Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304109 c.1179C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304121 c.1191A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304139 c.1209G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304162 p.Arg411His missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304165 p.Gly412Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304199 c.1269C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304202 c.1272G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304616 c.1686C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304688 c.1758C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304709 c.1779C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304712 c.1782C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304796 c.1866G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304797 p.Ala623Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304802 c.1872G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304859 c.1929C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304877 c.1947T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304887 c.1957C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304895 c.1965C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304911 c.1981C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304949 c.2019C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305051 c.2121G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305075 c.2145T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305084 c.2154C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305090 c.2160C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305114 c.2184T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305369 c.2439G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305400 p.His824Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305420 c.2490C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305447 c.2517C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305459 c.2529G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305462 c.2532G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305465 c.2535C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305474 c.2544T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305480 c.2550A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305484 p.Ala852Thr missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364805 c.393C>T synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427_429delTTGinsCT frameshift_variant&synonymous_variant 1.0 pyrazinamide Uncertain significance
sigE 1364844 c.432C>T synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>T synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364872 c.460_462delATCinsGT frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364895 p.Glu161Asp missense_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364921 p.Glu170Gly missense_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364926 p.Asn172Asp missense_variant 1.0 pyrazinamide
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.98 bedaquiline
atpE 1460849 c.-196G>T upstream_gene_variant 1.0 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460868 c.-177A>T upstream_gene_variant 1.0 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460888 c.-157C>A upstream_gene_variant 1.0 bedaquiline
atpE 1460897 c.-148A>G upstream_gene_variant 1.0 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 1.0 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461155 c.111C>T synonymous_variant 1.0 bedaquiline
atpE 1461161 c.117C>A synonymous_variant 1.0 bedaquiline
atpE 1461164 c.120C>G synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461173 c.129C>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
atpE 1461275 c.231T>A synonymous_variant 1.0 bedaquiline
atpE 1461281 c.237C>A synonymous_variant 1.0 bedaquiline
rrs 1471508 n.-338T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471514 n.-332A>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471541 n.-305G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471845 n.-1G>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471928 n.83T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471930 n.85_89delGGAGAinsTTGCAGGG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471996 n.151C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472045 n.200T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472055 n.210_211delCGinsT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472057 n.212C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472302 n.457G>A non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472306 n.461T>G non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472309 n.464C>G non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472311 n.466C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445delCinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473648 n.-9_-7delTTG upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473668 n.11C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473670 n.13A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473701 n.44A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473782 n.125A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473887 n.230T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473936 n.279A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474036 n.379G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474074 n.417C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474081 n.424C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474090 n.433C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474093 n.436G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474095 n.438A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474100 n.443_445delCCTinsTTGTCGC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474106 n.449A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474108 n.452_455delAATT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474287 n.630T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474288 n.632_633insGC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474292 n.636_646delTCCTCTCCGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 1.0 capreomycin