TB-Profiler result

Run: SRR9970978
Summary

Run ID: SRR9970978

Sample name:

Date: 2024-10-05T07:54:54.773562

Number of reads: 5339104

Percentage reads mapped: 32.61

Median coverage: 117.0

Strain: La1;lineage4.1.2

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1 Euro-American None 0.95
lineage4.1.2 Euro-American None 1.0
lineage3.1.2.2 East-African-Indian RD750 0.13
lineage4 Euro-American None 0.95
La1 M.bovis None 0.21
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 597 c.597C>G synonymous_variant 0.28 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>G synonymous_variant 0.33 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.39 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.39 isoniazid
dnaA 630 c.630C>G synonymous_variant 0.42 isoniazid
dnaA 633 c.633T>C synonymous_variant 0.42 isoniazid
dnaA 645 c.645A>G synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 648 c.648C>T synonymous_variant 0.41 isoniazid
dnaA 654 c.654A>G synonymous_variant 0.42 isoniazid
dnaA 663 c.663A>C synonymous_variant 0.36 isoniazid
dnaA 666 c.666C>A synonymous_variant 0.36 isoniazid Not assoc w R - Interim
dnaA 669 c.669C>T synonymous_variant 0.36 isoniazid
dnaA 681 c.681G>T synonymous_variant 0.32 isoniazid
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.32 isoniazid
dnaA 687 c.687C>T synonymous_variant 0.32 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.31 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.31 isoniazid
dnaA 699 c.699G>C synonymous_variant 0.31 isoniazid Not assoc w R - Interim
dnaA 702 c.702C>G synonymous_variant 0.3 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.31 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.31 isoniazid
dnaA 717 c.717C>A synonymous_variant 0.33 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 0.3 isoniazid
dnaA 750 c.750C>G synonymous_variant 0.27 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.24 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.19 isoniazid
dnaA 769 p.Ala257Ser missense_variant 0.18 isoniazid Uncertain significance
gyrB 6127 c.888G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 6169 c.930C>T synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6203 c.964_966delAGCinsTCG synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.47 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.48 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>A synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6325 c.-977C>G upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.35 levofloxacin
moxifloxacin
gyrB 6329 p.Glu364Gln missense_variant 0.36 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6550 c.-752A>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6556 c.-746C>G upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Thr missense_variant 0.22 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6631 c.-671C>T upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>T synonymous_variant 0.55 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6727 c.-575G>T upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.43 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7078 c.-224A>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrB 7100 c.1861T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 0.3 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>T upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.3 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7231 c.-71C>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7243 c.-59G>A upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7370 c.69G>A synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 7415 c.114C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 7436 c.135C>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.62 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7490 c.189C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7499 c.198G>T synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7550 c.249C>T synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7670 c.369A>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7671 p.Pro124Ala missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCGT synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGT synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTTG synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7802 c.501C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7844 c.543C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 7847 c.546G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8061 p.Arg254Cys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8339 c.1038A>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8378 c.1077C>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8421 p.Val374Ile missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>T synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.38 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8574 c.1273_1275delCTCinsTTG synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8649 p.Arg450Lys missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8669 c.1368C>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8672 c.1371A>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8777 c.1476C>T synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8798 p.Ile499Met missense_variant 0.23 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Pro missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8843 c.1542G>A synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8846 c.1545C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>G synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8936 c.1635G>A synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8952 p.Gln551Ala missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9059 c.1758G>A synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9206 c.1905C>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9213 p.Thr638Val missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.52 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.54 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9324 c.2023_2025delTCGinsAGT synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>T synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9377 c.2076A>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.32 levofloxacin
moxifloxacin
fgd1 491241 p.Asp153Glu missense_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491248 p.Arg156Thr missense_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.3 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491290 p.Val170Ile missense_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 0.29 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491307 c.525C>T synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491310 c.528C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491313 c.531C>T synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491316 c.534C>T synonymous_variant 0.25 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491321 p.Ala180Val missense_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491337 c.555C>G synonymous_variant 0.21 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491346 c.564C>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>C synonymous_variant 0.21 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491355 c.573C>T synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491364 c.582T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491490 c.708C>T synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491496 c.714C>T synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491499 c.717G>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491500 p.Glu240Lys missense_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Asp missense_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491536 c.754C>T synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491548 p.Ala256Pro missense_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491563 p.Ser261Trp missense_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491591 p.Lys270Met missense_variant 0.68 pretomanid
delamanid Uncertain significance
clofazimine Not assoc w R
fgd1 491598 c.816C>T synonymous_variant 0.32 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491601 c.819T>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 491604 c.822G>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491631 c.849C>T synonymous_variant 0.22 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491649 c.867C>T synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491655 c.873C>T synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491658 c.876A>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491661 c.879C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491664 c.882C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491667 c.885A>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491673 c.891A>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491679 c.897A>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491685 c.903G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491688 c.906A>G synonymous_variant 0.24 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491709 c.927A>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491712 c.930T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
mshA 575689 c.342G>C synonymous_variant 0.19 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 0.23 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.24 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 0.37 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.42 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.44 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 0.48 isoniazid Uncertain significance
ethionamide
mshA 575749 c.402C>G synonymous_variant 0.48 isoniazid
ethionamide
mshA 575756 c.409C>T synonymous_variant 0.48 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 0.47 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 0.46 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.45 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.45 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.45 isoniazid
ethionamide
mshA 575788 c.441C>T synonymous_variant 0.45 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 0.46 isoniazid
ethionamide
mshA 575809 c.462C>T synonymous_variant 0.47 isoniazid
ethionamide
mshA 575812 c.465C>T synonymous_variant 0.48 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.51 isoniazid
ethionamide
mshA 575845 c.498C>G synonymous_variant 0.51 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.43 isoniazid
ethionamide
mshA 575869 c.522G>C synonymous_variant 0.41 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.35 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.33 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.26 isoniazid
ethionamide
mshA 575905 c.558G>C synonymous_variant 0.22 isoniazid
ethionamide
mshA 575908 c.561A>C synonymous_variant 0.22 isoniazid Not assoc w R - Interim
ethionamide
mshA 575914 c.567C>T synonymous_variant 0.21 isoniazid
ethionamide
mshA 575916 p.Asp190Ala missense_variant 0.21 isoniazid
ethionamide
mshA 575920 c.573C>T synonymous_variant 0.22 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575924 p.Gly193Ser missense_variant 0.22 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.22 isoniazid
ethionamide
mshA 575945 p.Thr200Ala missense_variant 0.22 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.23 isoniazid
ethionamide
mshA 575965 c.618C>G synonymous_variant 0.2 isoniazid Not assoc w R - Interim
ethionamide
mshA 576108 p.Ala254Gly missense_variant 0.38 isoniazid
ethionamide
ccsA 620319 c.429C>T synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620332 c.442C>T synonymous_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 620335 c.445_447delCTCinsTTG synonymous_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>G synonymous_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Ser missense_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620370 c.480C>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>T synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>C synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620409 c.519C>G synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.32 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620439 c.549T>C synonymous_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620454 c.564C>G synonymous_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 620583 c.693G>C synonymous_variant 0.19 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620605 p.Val239Ile missense_variant 0.24 kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
ccsA 620625 c.735A>C synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620676 c.786C>T synonymous_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620724 c.834C>T synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620736 c.846G>T synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.51 kanamycin
capreomycin
amikacin
ccsA 620745 c.855G>C synonymous_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>C synonymous_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 620766 c.876C>G synonymous_variant 0.47 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>T synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620793 c.903G>C synonymous_variant 0.4 kanamycin
capreomycin
amikacin
ccsA 620796 c.906C>G synonymous_variant 0.4 kanamycin
capreomycin
amikacin
ccsA 620802 c.912C>G synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620808 c.918T>C synonymous_variant 0.41 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620818 p.Val310Ile missense_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620835 c.945C>T synonymous_variant 0.24 kanamycin
capreomycin
amikacin
Rv0565c 657269 p.Ser68Pro missense_variant 1.0 ethionamide Uncertain significance
nusG 734407 p.Val52Ile missense_variant 0.24 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.36 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.39 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.44 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.48 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.49 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.48 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.55 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.45 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>C synonymous_variant 0.21 rifampicin
nusG 734589 c.336G>C synonymous_variant 0.2 rifampicin
rpoB 760059 p.Tyr85Glu missense_variant 0.2 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.22 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.23 rifampicin
rpoB 760082 c.276C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 0.31 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.29 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.33 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.65 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.42 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.45 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.76 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.77 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.75 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.75 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.74 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760373 c.567C>T synonymous_variant 0.75 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.75 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.7 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.7 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 0.57 rifampicin
rpoB 760514 c.708C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.54 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.5 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.47 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.46 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.47 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.47 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.51 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.5 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.5 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.51 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.53 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.54 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.51 rifampicin
rpoB 760755 p.His317Asn missense_variant 0.52 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.52 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.53 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.54 rifampicin
rpoB 760784 c.978G>C synonymous_variant 0.55 rifampicin
rpoB 760787 c.981G>C synonymous_variant 0.55 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.56 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.57 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.55 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.57 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760856 c.1050C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.52 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.51 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.51 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.51 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.52 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.53 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.46 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.47 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.45 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.42 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.55 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.55 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761217 p.Pro471Ala missense_variant 0.54 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.54 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 0.6 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761339 c.1533C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.51 rifampicin
rpoB 761346 p.Val514Ile missense_variant 0.51 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.49 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 0.51 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.49 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.39 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.3 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 0.21 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.42 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.44 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.51 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.44 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.43 rifampicin
rpoB 761672 c.1866C>T synonymous_variant 0.44 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.45 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.44 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.43 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.43 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.43 rifampicin
rpoB 761702 c.1896C>A synonymous_variant 0.45 rifampicin
rpoB 761718 p.Ala638Ser missense_variant 0.42 rifampicin
rpoB 761723 p.GluSer640LysAla missense_variant 0.4 rifampicin
rpoB 761736 p.Ile644Val missense_variant 0.39 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 0.4 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.36 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.28 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.28 rifampicin
rpoB 761783 c.1977C>T synonymous_variant 0.29 rifampicin
rpoB 761784 p.Thr660Ser missense_variant 0.29 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.3 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.39 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.42 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 0.43 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 0.43 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.44 rifampicin
rpoB 761868 p.Asp688Gln missense_variant 0.43 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 0.45 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.46 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.45 rifampicin
rpoB 761892 p.Ile696Val missense_variant 0.45 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.45 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.43 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.44 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.45 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.46 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.49 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.51 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.57 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.57 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.66 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.65 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.65 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.63 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.63 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.71 rifampicin
rpoB 762293 c.2487T>G synonymous_variant 0.69 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.67 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.64 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.59 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.59 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.58 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.54 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.51 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.46 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.45 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.37 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.34 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762410 c.2604T>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 762776 c.-594C>T upstream_gene_variant 0.25 rifampicin
rpoB 762788 c.2982G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.26 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.26 rifampicin
rpoB 762798 p.Ala998Ser missense_variant 0.26 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762814 p.Met1003Thr missense_variant 0.37 rifampicin Uncertain significance
rpoB 762818 c.3012C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.45 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762878 p.Ile1024Met missense_variant 0.6 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.6 rifampicin Uncertain significance
rpoB 762929 c.3123G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>A synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.62 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763109 c.-261C>G upstream_gene_variant 0.63 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.6 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.63 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.66 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.67 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 0.61 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.59 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.58 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.58 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.51 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.51 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.5 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.5 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.5 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.43 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.4 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763289 c.-81C>G upstream_gene_variant 0.28 rifampicin
rpoC 763298 c.-72A>G upstream_gene_variant 0.19 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.34 rifampicin
rpoC 763417 c.48C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 0.35 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGC synonymous_variant 0.34 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.34 rifampicin
rpoC 763441 c.72C>G synonymous_variant 0.34 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.34 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.53 rifampicin
rpoC 763484 c.115_117delCTTinsTTG synonymous_variant 0.53 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.67 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>T synonymous_variant 0.72 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.72 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.68 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 0.66 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.67 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.69 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.69 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.69 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.62 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.57 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.58 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.49 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.47 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.47 rifampicin
rpoC 763852 c.483C>A synonymous_variant 0.51 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.48 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.49 rifampicin
rpoC 763871 p.Gly168Ser missense_variant 0.47 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.48 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.49 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.48 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.48 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.45 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.45 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.42 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.42 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.42 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.37 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.34 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.31 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.29 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.27 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.32 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.31 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.33 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.33 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.34 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.29 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.5 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.56 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.55 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.52 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 0.53 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.49 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.49 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.5 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.5 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.53 rifampicin
rpoC 764227 c.858G>C synonymous_variant 0.61 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.68 rifampicin
rpoC 764263 c.894G>A synonymous_variant 0.35 rifampicin Not assoc w R
rpoC 764263 c.894G>C synonymous_variant 0.65 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.66 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.68 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 0.71 rifampicin
rpoC 764293 c.924G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.7 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.78 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.52 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.53 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.53 rifampicin
rpoC 764455 c.1086G>C synonymous_variant 0.54 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.55 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.53 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.5 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.5 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.52 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.71 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.7 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.69 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.61 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.61 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.6 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.4 rifampicin
rpoC 765016 c.1647C>A synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765022 c.1653G>C synonymous_variant 0.39 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765070 c.1701G>C synonymous_variant 0.41 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.35 rifampicin
rpoC 765078 c.1710delT frameshift_variant 0.32 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.32 rifampicin
rpoC 765121 c.1752G>T synonymous_variant 0.19 rifampicin
rpoC 765150 p.Gly594Glu missense_variant 1.0 rifampicin Not assoc w R
rpoC 765364 p.Glu665Asp missense_variant 0.17 rifampicin
rpoC 765379 c.2010G>T synonymous_variant 0.28 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.28 rifampicin Uncertain significance
rpoC 765403 c.2034G>C synonymous_variant 0.33 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.33 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.33 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.33 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.34 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.36 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.42 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.4 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.38 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765533 p.Tyr722His missense_variant 0.27 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.22 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.21 rifampicin
rpoC 765577 c.2208G>T synonymous_variant 0.21 rifampicin
rpoC 765738 p.Arg790Gln missense_variant 0.17 rifampicin
rpoC 765743 p.His792Tyr missense_variant 0.19 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.22 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.25 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.35 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 0.35 rifampicin
rpoC 765779 p.Asp804Lys missense_variant 0.34 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.38 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.4 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.42 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.45 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 0.49 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.5 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.65 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.67 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.7 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.68 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.64 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.62 rifampicin
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 0.61 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.4 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 0.35 rifampicin
rpoC 766034 p.His889Asn missense_variant 0.3 rifampicin
rpoC 766042 c.2673C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Glu missense_variant 0.22 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.21 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.21 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.22 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.23 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.25 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.27 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.28 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.25 rifampicin
rpoC 766428 c.3059_3060insTAC disruptive_inframe_insertion 0.26 rifampicin
rpoC 766433 c.3065delA frameshift_variant 0.26 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 0.27 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 0.31 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 0.24 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.16 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.25 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 0.25 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.25 rifampicin
rpoC 766634 p.Phe1089Ile missense_variant 0.25 rifampicin
rpoC 766638 p.Lys1090Thr missense_variant 0.25 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.28 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.32 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 0.35 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.41 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.43 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.45 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.49 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.5 rifampicin
rpoC 766694 p.Gln1109Asp missense_variant 0.5 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.56 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 0.57 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.57 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.58 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.59 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.6 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.54 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.54 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.54 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.47 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.46 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.47 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.47 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.49 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.49 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.49 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.54 rifampicin
rpoC 766931 p.Ala1188Thr missense_variant 0.53 rifampicin Uncertain significance
rpoC 766942 c.3573C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.49 rifampicin
rpoC 766960 c.3591C>T synonymous_variant 0.52 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 0.48 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>C synonymous_variant 0.65 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.6 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.5 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.5 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.48 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.47 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>A synonymous_variant 0.33 rifampicin
rpoC 767233 c.3864T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.25 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775814 c.2667C>G synonymous_variant 0.18 bedaquiline
clofazimine
mmpL5 775817 c.2664T>C synonymous_variant 0.44 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775829 c.2652C>G synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775832 p.Ala883Ser missense_variant 0.22 bedaquiline
clofazimine
mmpL5 775835 c.2646C>G synonymous_variant 0.24 bedaquiline
clofazimine
mmpL5 775838 c.2643G>C synonymous_variant 0.28 bedaquiline
clofazimine
mmpL5 775847 c.2634G>C synonymous_variant 0.4 bedaquiline
clofazimine
mmpL5 775851 p.Ser877Thr missense_variant 0.3 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.56 bedaquiline
clofazimine
mmpL5 775862 c.2619G>C synonymous_variant 0.56 bedaquiline
clofazimine
mmpL5 775865 c.2616T>C synonymous_variant 0.41 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.28 bedaquiline
clofazimine
mmpL5 775886 c.2595A>T synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 775889 c.2592C>A synonymous_variant 0.29 bedaquiline
clofazimine
mmpL5 775893 p.His863Pro missense_variant 0.26 bedaquiline
clofazimine
mmpL5 775895 p.Ile862Leu missense_variant 0.39 bedaquiline
clofazimine
mmpL5 775904 c.2577G>A synonymous_variant 0.53 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.31 bedaquiline
clofazimine
mmpL5 775910 c.2569_2571delCGGinsAGA synonymous_variant 0.27 bedaquiline
clofazimine
mmpL5 775913 p.Ala856Ser missense_variant 0.23 bedaquiline
clofazimine
mmpL5 775916 c.2565T>G synonymous_variant 0.37 bedaquiline
clofazimine
mmpL5 775921 c.2560C>T synonymous_variant 0.2 bedaquiline
clofazimine
mmpL5 775946 c.2535C>G synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 775951 c.2530C>T synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 775955 p.Ile842Val missense_variant 0.33 bedaquiline
clofazimine
mmpL5 775961 c.2520C>G synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.33 bedaquiline
clofazimine
mmpL5 775970 c.2511G>C synonymous_variant 0.25 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.41 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.51 bedaquiline
clofazimine
mmpL5 775991 c.2490G>A synonymous_variant 0.49 bedaquiline
clofazimine
mmpL5 775994 p.Ile829Leu missense_variant 0.47 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.43 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.47 bedaquiline
clofazimine
mmpL5 776003 p.Ile826Leu missense_variant 0.47 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.51 bedaquiline
clofazimine
mmpL5 776018 c.2463G>C synonymous_variant 0.52 bedaquiline
clofazimine
mmpL5 776030 c.2451G>C synonymous_variant 0.46 bedaquiline
clofazimine
mmpL5 776036 c.2445G>C synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 0.46 bedaquiline
clofazimine
mmpL5 776075 c.2406C>G synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 776081 c.2400G>C synonymous_variant 0.27 bedaquiline
clofazimine
mmpL5 776084 c.2397C>G synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 776087 c.2394C>G synonymous_variant 0.25 bedaquiline
clofazimine
mmpL5 776096 c.2385C>G synonymous_variant 0.23 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Leu missense_variant 0.23 bedaquiline
clofazimine
mmpL5 776107 c.2374C>T synonymous_variant 0.22 bedaquiline
clofazimine
mmpL5 776120 c.2361C>T synonymous_variant 0.2 bedaquiline
clofazimine
mmpL5 776132 c.2349A>G synonymous_variant 0.19 bedaquiline
clofazimine
mmpL5 776137 p.Ser782Ala missense_variant 0.19 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776201 c.2280T>C synonymous_variant 0.17 bedaquiline
clofazimine
mmpL5 776207 c.2274G>C synonymous_variant 0.22 bedaquiline
clofazimine
mmpL5 776217 p.Ala755Lys missense_variant 0.24 bedaquiline
clofazimine
mmpL5 776222 c.2259A>T synonymous_variant 0.24 bedaquiline
clofazimine
mmpL5 776230 c.2251T>C synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 776234 c.2247A>C synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 776246 c.2235C>G synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 776249 c.2232A>G synonymous_variant 0.25 bedaquiline
clofazimine
mmpL5 776262 p.Thr740Asn missense_variant 0.28 bedaquiline
clofazimine
mmpL5 776271 p.Lys737Ala missense_variant 0.29 bedaquiline
clofazimine
mmpL5 776273 p.Ala736Asp missense_variant 0.29 bedaquiline
clofazimine
mmpL5 776280 p.Arg734His missense_variant 0.28 bedaquiline
clofazimine
mmpL5 776284 p.Ala733Ser missense_variant 0.28 bedaquiline
clofazimine
mmpL5 776292 p.Ala730Glu missense_variant 0.28 bedaquiline
clofazimine
mmpL5 776294 p.Gln729Pro missense_variant 0.28 bedaquiline
clofazimine
mmpL5 776312 c.2169A>G synonymous_variant 0.28 bedaquiline
clofazimine
mmpL5 776336 c.2145G>C synonymous_variant 0.25 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 776342 c.2139G>A synonymous_variant 0.23 bedaquiline
clofazimine
mmpL5 777133 p.Val450Ile missense_variant 0.18 bedaquiline
clofazimine
mmpL5 777206 c.1275A>G synonymous_variant 0.2 bedaquiline
clofazimine
mmpL5 777209 c.1272C>T synonymous_variant 0.21 bedaquiline
clofazimine
mmpL5 777224 p.Asn419Lys missense_variant 0.22 bedaquiline
clofazimine
mmpL5 777246 p.Arg412Lys missense_variant 0.18 bedaquiline
clofazimine
mmpL5 777251 c.1230C>G synonymous_variant 0.18 bedaquiline
clofazimine
mmpL5 777254 c.1227G>C synonymous_variant 0.19 bedaquiline
clofazimine
mmpL5 777320 c.1161C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781559 c.-1G>C upstream_gene_variant 0.2 streptomycin
rpsL 781572 p.Gln5Asn missense_variant 0.26 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.36 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.36 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.34 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.35 streptomycin
rpsL 781622 c.63C>G synonymous_variant 0.36 streptomycin
rpsL 781631 c.72G>C synonymous_variant 0.37 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.47 streptomycin
rpsL 781652 c.93T>C synonymous_variant 0.48 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.51 streptomycin
rpsL 781664 c.105C>G synonymous_variant 0.52 streptomycin
rpsL 781667 c.108C>T synonymous_variant 0.53 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.56 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.55 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.54 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.54 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.51 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.5 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.47 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.46 streptomycin
rpsL 781737 p.Gln60Gly missense_variant 0.45 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.48 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.52 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.54 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.55 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.58 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.58 streptomycin Not assoc w R - Interim
rpsL 781793 c.234G>C synonymous_variant 0.59 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.59 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.59 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.58 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.56 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.57 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.57 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.6 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.61 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.61 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.61 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.62 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.6 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.6 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.58 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.57 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.57 streptomycin Uncertain significance
rplC 800200 c.-609C>G upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 0.4 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.51 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.52 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.54 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.53 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.52 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.54 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.55 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.54 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.54 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.55 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.56 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.58 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.6 linezolid
rplC 800642 c.-167C>T upstream_gene_variant 0.6 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.61 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.61 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.62 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.62 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.61 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.57 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.55 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.54 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.53 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.52 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.53 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.48 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.44 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.42 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.36 linezolid
rplC 800877 c.69A>C synonymous_variant 0.18 linezolid
rplC 800880 c.72A>C synonymous_variant 0.18 linezolid
rplC 800889 c.81C>G synonymous_variant 0.19 linezolid
rplC 800892 c.84G>C synonymous_variant 0.21 linezolid
rplC 800904 c.96G>C synonymous_variant 0.27 linezolid
rplC 800916 c.108A>G synonymous_variant 0.27 linezolid
rplC 800921 p.Arg38Leu missense_variant 0.28 linezolid
rplC 800928 c.120C>T synonymous_variant 0.28 linezolid
rplC 800931 c.123G>C synonymous_variant 0.29 linezolid
rplC 800937 c.129A>G synonymous_variant 0.29 linezolid
rplC 800946 c.138T>C synonymous_variant 0.29 linezolid
rplC 800949 c.141T>C synonymous_variant 0.29 linezolid
rplC 800964 c.156G>C synonymous_variant 0.28 linezolid
rplC 800985 c.177A>G synonymous_variant 0.25 linezolid
fbiC 1303509 c.579G>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1303531 p.Met201Leu missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303542 c.612C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303548 c.618G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303593 c.663G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304403 c.1473T>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1304418 c.1488T>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304424 c.1494C>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304430 c.1500A>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304436 c.1506G>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304439 c.1509G>A synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304442 c.1512T>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304444 p.Ala505Asp missense_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304450 p.Ala507Gly missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304459 p.Thr510Ser missense_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304465 p.Gly512Asp missense_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304472 c.1542T>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1304475 c.1545G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304481 c.1551T>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304490 c.1560C>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304496 c.1566T>A synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304499 c.1569T>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304515 p.Ala529Thr missense_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304655 c.1725C>T synonymous_variant 0.49 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304658 c.1728C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304706 c.1776C>T synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304727 c.1797A>C synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304760 c.1830G>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304769 c.1839C>G synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1304775 c.1845C>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304802 c.1872G>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304826 c.1896G>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>G synonymous_variant 0.22 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304835 c.1905G>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
sigE 1364715 c.303G>C synonymous_variant 0.23 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.22 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.22 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 0.28 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.39 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.41 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.43 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 0.45 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.48 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.5 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.53 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.5 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.51 pyrazinamide
sigE 1364818 c.406_408delCTAinsTTG synonymous_variant 0.52 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.48 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 0.46 pyrazinamide
sigE 1364862 c.450C>T synonymous_variant 0.44 pyrazinamide
sigE 1364865 c.453G>T synonymous_variant 0.42 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.42 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.41 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.39 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.26 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.24 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.23 pyrazinamide
atpE 1461116 c.72C>T synonymous_variant 0.17 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.29 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.31 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.33 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.33 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.33 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.33 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.35 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.35 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.35 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.35 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.37 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.36 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.36 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 0.35 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.36 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.27 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.26 bedaquiline
rrs 1471644 n.-202T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.56 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.56 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.72 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472032 n.187G>T non_coding_transcript_exon_variant 0.68 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>G non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.78 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.35 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.33 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.34 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.33 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.33 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.32 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.34 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 0.34 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.77 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.78 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.8 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.79 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.79 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.78 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.73 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1474022 n.365G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474044 n.387C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1474045 n.388C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1474053 n.396G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474101 n.446_450delAGTAT non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474108 n.451C>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474110 n.454_455insGGTGT non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631_632delCCinsTCGACT non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474292 n.635T>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474415 n.760_765delACACGC non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474426 n.769T>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474428 n.771C>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474430 n.773C>A non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAAT non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475382 n.1725A>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475395 n.1738T>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid Uncertain significance
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476031 n.2374_2378delCCTCGinsTTCAC non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.79 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.76 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.77 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
inhA 1673709 c.-493C>T upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsCA upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.25 isoniazid
ethionamide
inhA 1673749 c.-453_-451delAAGinsCGA upstream_gene_variant 0.25 isoniazid
ethionamide
inhA 1673760 c.-442G>C upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673784 c.-418G>T upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673799 c.-403T>G upstream_gene_variant 0.43 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 0.43 isoniazid
ethionamide
inhA 1673808 c.-394A>T upstream_gene_variant 0.44 isoniazid
ethionamide
inhA 1673829 c.-373C>G upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673830 c.-372_-370delAAAinsCGT upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673841 c.-361A>G upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673844 c.-358G>C upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673853 c.-349A>C upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1673856 c.-346T>C upstream_gene_variant 0.39 isoniazid
ethionamide
inhA 1673865 c.-337C>G upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673870 c.-332_-331delGCinsTG upstream_gene_variant 0.44 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 0.51 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673916 c.-286A>T upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.44 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1673946 c.-256C>G upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673949 c.-253G>A upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673962 c.-240_-239delAAinsGG upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673967 c.-235G>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673973 c.-229G>C upstream_gene_variant 0.3 isoniazid Uncertain significance
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673985 c.-217C>A upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673988 c.-214G>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1674003 c.-199C>G upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1674018 c.-184G>C upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1674399 c.198A>G synonymous_variant 0.19 isoniazid
ethionamide
inhA 1674418 p.Ser73Gly missense_variant 0.31 isoniazid
ethionamide
inhA 1674421 c.220T>C synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674428 p.Gly76Asp missense_variant 0.39 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 0.42 isoniazid
ethionamide
inhA 1674444 c.243G>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674450 c.249G>T synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674471 c.270G>C synonymous_variant 0.52 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.52 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674489 c.288G>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674503 p.Thr101Ser missense_variant 0.51 isoniazid
ethionamide
inhA 1674507 c.306G>T synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674513 c.312C>T synonymous_variant 0.49 isoniazid
ethionamide
inhA 1674514 p.Ile105Val missense_variant 0.48 isoniazid
ethionamide
inhA 1674522 c.321G>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674531 c.330C>T synonymous_variant 0.54 isoniazid
ethionamide
inhA 1674534 c.333G>T synonymous_variant 0.55 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.55 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 0.5 isoniazid
ethionamide
inhA 1674573 c.372G>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.43 isoniazid
ethionamide
inhA 1674585 c.384T>G synonymous_variant 0.42 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 0.42 isoniazid
ethionamide
inhA 1674600 c.399G>C synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674610 p.Ile137Val missense_variant 0.33 isoniazid
ethionamide
inhA 1674619 p.Pro140Glu missense_variant 0.3 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.32 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674628 p.Ser143Gly missense_variant 0.3 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 0.41 isoniazid
ethionamide
inhA 1674669 c.468G>T synonymous_variant 0.42 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 0.33 isoniazid
ethionamide
inhA 1674703 c.502_504delTTGinsCTC synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.33 isoniazid
ethionamide
inhA 1674726 c.525G>C synonymous_variant 0.36 isoniazid
ethionamide
inhA 1674732 c.531C>T synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674746 p.Tyr182Phe missense_variant 0.42 isoniazid
ethionamide
inhA 1674756 c.555T>G synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674762 c.561T>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674771 c.570C>G synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.49 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674795 c.594G>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674816 c.615T>C synonymous_variant 0.51 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674819 c.618G>C synonymous_variant 0.52 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674828 p.Glu209Asp missense_variant 0.51 isoniazid
ethionamide
inhA 1674838 p.Ala213Lys missense_variant 0.49 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.51 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.42 isoniazid
ethionamide
inhA 1674924 c.723G>C synonymous_variant 0.34 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 0.2 isoniazid
ethionamide
rpsA 1833547 c.6G>A synonymous_variant 0.18 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.21 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.34 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.33 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.33 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.4 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.43 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.46 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.49 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.53 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.55 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.56 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.56 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.57 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.57 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.59 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.56 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.55 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.56 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.56 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.56 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.6 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.56 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.57 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.6 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.61 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.59 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.59 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.59 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.59 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.61 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.6 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.59 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.61 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.64 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.65 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.64 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.64 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.64 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.66 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.68 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.69 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.66 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.59 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.57 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.56 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.56 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.62 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.66 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.67 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.68 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.64 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.63 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.62 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 0.58 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.56 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.56 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.51 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.51 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.5 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.5 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.51 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.41 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.44 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.46 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.46 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.43 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.43 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.45 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.42 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.42 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.42 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.43 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.43 pyrazinamide
rpsA 1834829 p.Ala430Thr missense_variant 0.24 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.51 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.52 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.52 linezolid
tsnR 1853384 c.-222G>T upstream_gene_variant 0.52 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.5 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.52 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.53 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.51 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.5 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.48 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.48 linezolid
tsnR 1853441 c.-165C>A upstream_gene_variant 0.4 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.28 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.24 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.2 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2155691 c.421T>C synonymous_variant 0.2 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.23 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.26 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.27 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.26 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.26 isoniazid
katG 2155743 c.369G>A synonymous_variant 0.25 isoniazid Not assoc w R - Interim
katG 2155747 p.Ala122Gly missense_variant 0.26 isoniazid
katG 2155764 p.His116Gln missense_variant 0.23 isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517917 c.-198G>T upstream_gene_variant 0.56 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.51 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.5 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.49 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.48 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.47 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.44 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 0.42 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.36 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.36 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.16 isoniazid
kasA 2518076 c.-39C>T upstream_gene_variant 1.0 isoniazid
kasA 2518636 c.522C>A synonymous_variant 0.22 isoniazid
kasA 2518639 c.525G>T synonymous_variant 0.21 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.21 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.21 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 0.21 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.22 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.22 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.3 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.35 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.39 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.37 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.35 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.36 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.36 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.36 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.35 isoniazid
kasA 2518798 c.684G>A synonymous_variant 0.38 isoniazid
kasA 2518822 c.708C>A synonymous_variant 0.39 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.38 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.39 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.39 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.41 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.37 isoniazid
kasA 2518873 c.759C>T synonymous_variant 0.31 isoniazid
kasA 2518877 p.Lys255Leu missense_variant 0.28 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.2 isoniazid
kasA 2519209 c.1095C>G synonymous_variant 0.21 isoniazid
kasA 2519218 c.1104G>C synonymous_variant 0.21 isoniazid
kasA 2519224 c.1110C>G synonymous_variant 0.21 isoniazid
kasA 2519227 c.1113G>T synonymous_variant 0.21 isoniazid
kasA 2519242 c.1128C>T synonymous_variant 0.2 isoniazid
kasA 2519248 c.1134C>T synonymous_variant 0.19 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 0.18 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 0.18 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 0.18 isoniazid
ahpC 2726606 c.414C>G synonymous_variant 0.17 isoniazid
ahpC 2726609 c.417C>T synonymous_variant 0.18 isoniazid
ahpC 2726624 c.432C>T synonymous_variant 0.2 isoniazid Not assoc w R - Interim
ahpC 2726638 p.Ala149Val missense_variant 0.23 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.22 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 0.23 isoniazid
ahpC 2726654 c.462G>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
ahpC 2726657 c.465A>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
ahpC 2726663 c.471C>T synonymous_variant 0.24 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 0.24 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.24 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.24 isoniazid Not assoc w R - Interim
ahpC 2726693 c.501C>A synonymous_variant 0.23 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.23 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.21 isoniazid
folC 2747257 c.342G>C synonymous_variant 0.18 para-aminosalicylic_acid
folC 2747263 c.336C>A synonymous_variant 0.2 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.2 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.2 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.22 para-aminosalicylic_acid
folC 2747290 c.309A>C synonymous_variant 0.22 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.25 para-aminosalicylic_acid
folC 2747317 c.282C>A synonymous_variant 0.24 para-aminosalicylic_acid
folC 2747320 c.279C>G synonymous_variant 0.24 para-aminosalicylic_acid
folC 2747341 p.Val86Leu missense_variant 0.23 para-aminosalicylic_acid
folC 2747350 c.249C>T synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747356 p.Met81Ile missense_variant 0.23 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 0.24 para-aminosalicylic_acid
folC 2747377 c.222C>G synonymous_variant 0.19 para-aminosalicylic_acid
folC 2747386 c.213C>G synonymous_variant 0.19 para-aminosalicylic_acid
Rv2477c 2782633 c.1410G>C synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782668 p.Gln459Glu missense_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782675 c.1368G>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782680 c.1363T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782684 c.1359T>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782690 c.1353C>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782695 c.1348A>C synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782705 c.1338G>C synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782708 c.1335C>T synonymous_variant 0.22 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782714 c.1329A>G synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782720 c.1323T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782723 c.1320C>G synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782726 c.1317G>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782732 c.1311A>G synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782738 c.1305C>T synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782744 c.1299A>T synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782750 c.1293T>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782759 c.1284A>G synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782762 c.1281G>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783377 c.666C>G synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>A synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783488 c.555G>A synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783516 c.526_527delTCinsAG synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>T synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.47 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>T synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783584 p.Ala153Pro missense_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783596 c.447C>T synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783626 p.Ala139Ser missense_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783635 c.408C>T synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783650 p.His131Ala missense_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783671 p.Arg124His missense_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783695 c.348C>T synonymous_variant 0.34 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2680 2996085 c.-20G>A upstream_gene_variant 0.55 capreomycin Uncertain significance
Rv2680 2996136 p.Ser11Asn missense_variant 0.19 capreomycin
Rv2752c 3065025 c.1167G>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol
Rv2752c 3065055 c.1137T>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065058 c.1134C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065061 c.1131C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065064 c.1128G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065097 c.1095C>T synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065106 c.1086C>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065111 c.1081A>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065126 p.Ser356Ala missense_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065129 c.1063C>T synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065133 c.1059T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065142 c.1050A>G synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065148 c.1044C>G synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067631 c.315C>A synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067676 c.270C>T synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067680 p.Cys89Ala missense_variant 0.39 para-aminosalicylic_acid
thyX 3067688 c.258G>C synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067698 p.Thr83Ser missense_variant 0.4 para-aminosalicylic_acid
thyX 3067709 c.237G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067724 c.222G>A synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.43 para-aminosalicylic_acid
thyX 3067771 p.Gly59Ser missense_variant 0.4 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067784 c.162C>G synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067788 p.Lys53Arg missense_variant 0.33 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067808 c.138C>T synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067839 p.Val36Thr missense_variant 0.26 para-aminosalicylic_acid
thyX 3067841 c.105G>C synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067847 c.99C>T synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.24 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067883 c.63C>T synonymous_variant 0.18 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073857 c.615C>T synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.34 para-aminosalicylic_acid
thyA 3073881 c.591C>G synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3073887 p.Ser195Gly missense_variant 0.33 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3073893 c.579C>A synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3073899 c.573G>A synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3073905 c.567C>T synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3073926 c.546G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3073980 c.492C>T synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3073994 p.Ser160Cys missense_variant 0.19 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087641 c.822T>C synonymous_variant 0.24 cycloserine
ald 3087647 c.828A>G synonymous_variant 0.23 cycloserine
ald 3087649 p.Gly277Asp missense_variant 0.23 cycloserine
ald 3087653 c.834A>G synonymous_variant 0.23 cycloserine
ald 3087656 c.837A>T synonymous_variant 0.24 cycloserine
ald 3087659 c.840G>C synonymous_variant 0.25 cycloserine
ald 3087666 p.Tyr283His missense_variant 0.26 cycloserine
ald 3087672 p.His285Asp missense_variant 0.25 cycloserine
ald 3087699 p.Leu294Val missense_variant 0.25 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.25 cycloserine
ald 3087713 c.894G>C synonymous_variant 0.24 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.23 cycloserine
ald 3087727 p.Ala303Gly missense_variant 0.22 cycloserine
ald 3087738 p.Lys307Arg missense_variant 0.21 cycloserine
ald 3087749 c.930C>G synonymous_variant 0.21 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 0.21 cycloserine
Rv3236c 3611974 c.1143A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
lpqB 3624635 p.His92Arg missense_variant 0.2 rifampicin Uncertain significance
bedaquiline
lpqB 3624643 p.Ile90Leu missense_variant 0.19 rifampicin
bedaquiline
lpqB 3624646 c.265T>C synonymous_variant 0.19 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 0.2 rifampicin
bedaquiline
lpqB 3624656 c.255C>T synonymous_variant 0.21 rifampicin
bedaquiline
lpqB 3624673 p.Ala80Ser missense_variant 0.21 rifampicin
bedaquiline
lpqB 3624674 p.Asn79Ser missense_variant 0.2 rifampicin
bedaquiline
lpqB 3624686 p.Glu75Asp missense_variant 0.2 rifampicin
bedaquiline
lpqB 3624701 c.210T>G synonymous_variant 0.2 rifampicin
bedaquiline
lpqB 3624704 c.207G>C synonymous_variant 0.2 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624725 c.186G>C synonymous_variant 0.23 rifampicin
bedaquiline
lpqB 3624728 c.183C>T synonymous_variant 0.23 rifampicin
bedaquiline
lpqB 3624734 c.177A>T synonymous_variant 0.24 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624770 c.141T>C synonymous_variant 0.16 rifampicin
bedaquiline
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3625078 c.-168G>C upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3625095 p.Glu507Lys missense_variant 0.35 rifampicin
bedaquiline
lpqB 3625099 c.-189C>G upstream_gene_variant 0.39 rifampicin
bedaquiline
lpqB 3625111 c.-201G>C upstream_gene_variant 0.41 rifampicin
bedaquiline
lpqB 3625117 c.-209_-207delCTTinsTTG upstream_gene_variant 0.41 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.42 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 0.45 rifampicin
bedaquiline
lpqB 3625135 c.-225A>C upstream_gene_variant 0.47 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 0.51 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 0.58 rifampicin
bedaquiline
lpqB 3625156 c.-246G>C upstream_gene_variant 0.59 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.6 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625183 c.-273G>T upstream_gene_variant 0.63 rifampicin
bedaquiline
lpqB 3625186 c.-276T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.64 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.64 rifampicin
bedaquiline
lpqB 3625207 c.-297C>G upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 0.61 rifampicin
bedaquiline
lpqB 3625246 c.-336G>C upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3625252 c.1362G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625255 c.-345T>C upstream_gene_variant 0.62 rifampicin
bedaquiline
lpqB 3625258 c.-348G>C upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3625262 p.Tyr451Phe missense_variant 0.63 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 0.63 rifampicin
bedaquiline
lpqB 3625285 c.-375G>C upstream_gene_variant 0.62 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 0.61 rifampicin
bedaquiline
lpqB 3625312 c.-402G>C upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrB 3625325 p.His430Arg missense_variant 0.5 rifampicin
bedaquiline
lpqB 3625336 c.-426C>T upstream_gene_variant 0.49 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3625351 c.1263T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625354 c.-444G>C upstream_gene_variant 0.39 rifampicin
bedaquiline
lpqB 3625375 c.-465A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
lpqB 3625384 c.-474G>C upstream_gene_variant 0.22 rifampicin
bedaquiline
lpqB 3625579 c.-669A>C upstream_gene_variant 0.18 rifampicin
bedaquiline
mtrB 3625592 p.Ser341Asn missense_variant 0.27 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
lpqB 3625603 c.-693G>A upstream_gene_variant 0.41 rifampicin
bedaquiline
lpqB 3625615 c.-705G>A upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3625623 p.Thr331Ala missense_variant 0.47 rifampicin
bedaquiline
mtrB 3625633 c.981C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625636 p.Ala326Glu missense_variant 0.45 rifampicin
bedaquiline
lpqB 3625639 c.-729C>T upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3625648 p.Tyr322His missense_variant 0.46 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625669 c.-759G>C upstream_gene_variant 0.54 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.59 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625714 c.-804C>T upstream_gene_variant 0.63 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625735 c.879C>A synonymous_variant 0.59 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625741 c.-831G>A upstream_gene_variant 0.57 rifampicin
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625753 p.Ala287Gln missense_variant 0.5 rifampicin
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.22 rifampicin
bedaquiline
mtrA 3626711 p.Thr213Gln missense_variant 0.22 rifampicin
bedaquiline
mtrB 3626723 c.-110C>G upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrA 3626749 c.601C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3626773 c.-160C>T upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGT upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3626783 c.-170C>T upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3626786 c.-173A>C upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626843 c.-230G>A upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.27 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3626864 c.-253_-251delTTGinsCTC upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3626894 c.-281C>T upstream_gene_variant 0.17 rifampicin
bedaquiline
mtrB 3627023 c.-410C>G upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrA 3627041 p.Ile103Val missense_variant 0.34 rifampicin
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3627098 c.-485A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3627110 c.-497G>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3627125 c.-512C>G upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3627134 c.-521C>T upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrB 3627139 c.-526T>C upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrB 3627143 c.-530G>T upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTT upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627191 c.-578G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627200 c.-587C>T upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627212 c.-599C>T upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627215 c.-602G>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3627224 c.-611G>C upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3627227 c.-614T>G upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrA 3627234 p.Thr39Ser missense_variant 0.34 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrA 3627239 c.111C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3627263 c.-650C>A upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrA 3627269 c.81G>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrA 3627277 c.73C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627278 c.-665G>C upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.24 rifampicin
bedaquiline
fbiB 3642602 c.1068A>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiB 3642605 c.1071A>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiB 3642614 c.1080C>T synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiB 3642622 p.Ala363Asp missense_variant 0.18 pretomanid
delamanid
clofazimine
fbiB 3642633 p.Asp367His missense_variant 0.19 pretomanid
delamanid
clofazimine
fbiB 3642656 c.1122G>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiB 3642665 c.1131C>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiB 3642668 c.1134A>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiB 3642674 c.1140C>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiB 3642677 c.1143A>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiB 3642680 c.1146A>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiB 3642684 c.1150T>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiB 3642698 c.1164G>C synonymous_variant 0.22 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiB 3642701 c.1167C>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiB 3642709 p.Gly392Glu missense_variant 0.21 pretomanid
delamanid
clofazimine
fbiB 3642711 p.Leu393Val missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiB 3642719 c.1185T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
rpoA 3877534 p.Val325Ala missense_variant 0.19 rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.18 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 0.19 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 0.19 rifampicin
rpoA 3877569 p.Pro313Ala missense_variant 0.19 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.34 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.56 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.56 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.55 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.53 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.66 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.63 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.64 rifampicin
rpoA 3877749 c.759C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877770 c.735_738delGTCAinsCAGC synonymous_variant 0.59 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877803 c.705G>C synonymous_variant 0.61 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.65 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.6 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.57 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 0.57 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.52 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.45 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 0.44 rifampicin
rpoA 3877980 c.528C>T synonymous_variant 0.43 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 0.35 rifampicin
rpoA 3877998 c.510G>C synonymous_variant 0.34 rifampicin
rpoA 3878001 c.505_507delTCAinsAGC synonymous_variant 0.33 rifampicin
rpoA 3878019 c.489A>G synonymous_variant 0.24 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.18 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.18 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.18 rifampicin
rpoA 3878064 c.444G>C synonymous_variant 0.23 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.34 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.39 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.43 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.49 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.54 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.56 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.55 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.65 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3878232 c.276G>C synonymous_variant 0.61 rifampicin
rpoA 3878238 c.270C>T synonymous_variant 0.6 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 0.58 rifampicin
rpoA 3878247 c.261G>T synonymous_variant 0.58 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.56 rifampicin
rpoA 3878262 p.Ser82Gly missense_variant 0.51 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.44 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 0.35 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.25 rifampicin
rpoA 3878352 c.156C>G synonymous_variant 0.24 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.22 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.24 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3878400 c.108T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 0.21 rifampicin
rpoA 3878409 c.99C>G synonymous_variant 0.21 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.22 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.2 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.2 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.19 rifampicin
rpoA 3878450 p.Gln20Lys missense_variant 0.18 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.19 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.19 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 0.27 rifampicin
rpoA 3878886 c.-379G>A upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoA 3878890 c.-383C>G upstream_gene_variant 0.25 rifampicin
rpoA 3878893 c.-388_-386delCACinsAAG upstream_gene_variant 0.25 rifampicin
rpoA 3878896 c.-389G>C upstream_gene_variant 0.25 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.27 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.27 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.28 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.27 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.28 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 0.25 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGTG upstream_gene_variant 0.22 rifampicin
rpoA 3878977 c.-470C>G upstream_gene_variant 0.22 rifampicin
rpoA 3878989 c.-482G>T upstream_gene_variant 0.22 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.17 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoA 3879097 c.-590C>T upstream_gene_variant 0.19 rifampicin
rpoA 3879123 c.-616C>A upstream_gene_variant 0.19 rifampicin
clpC1 4038271 p.Pro812Ala missense_variant 0.19 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.2 pyrazinamide
clpC1 4038288 p.Asn806Gly missense_variant 0.2 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.23 pyrazinamide
clpC1 4038310 p.Val799Leu missense_variant 0.36 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.36 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.35 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.36 pyrazinamide
clpC1 4038323 p.Val794Leu missense_variant 0.36 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 0.45 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.47 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.48 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.49 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.57 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.56 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCTC synonymous_variant 0.54 pyrazinamide
clpC1 4038410 c.2295C>T synonymous_variant 0.56 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.57 pyrazinamide
clpC1 4038428 c.2277G>C synonymous_variant 0.58 pyrazinamide
clpC1 4038434 c.2271G>C synonymous_variant 0.59 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.54 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.54 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.6 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.61 pyrazinamide
clpC1 4038474 p.Ser744Ala missense_variant 0.61 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.63 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.63 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.64 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.61 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.61 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.61 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.61 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.61 pyrazinamide
clpC1 4038584 c.2121G>T synonymous_variant 0.58 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.58 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.59 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.59 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.54 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.48 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.45 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.39 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.38 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.38 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 0.4 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.41 pyrazinamide
clpC1 4038683 c.2020_2022delTCTinsAGC synonymous_variant 0.42 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.43 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.42 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.43 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 0.46 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.46 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.46 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.46 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.44 pyrazinamide
clpC1 4038770 c.1935C>A synonymous_variant 0.44 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.44 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.44 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.45 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.53 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.53 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.54 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 0.51 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.51 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.5 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.5 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.53 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.58 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.57 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.59 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.66 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.7 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.71 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.71 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.73 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.71 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.7 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.7 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.64 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 0.6 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.6 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 0.54 pyrazinamide
clpC1 4039268 c.1437C>T synonymous_variant 0.52 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>T synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.48 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.44 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.42 pyrazinamide
clpC1 4039319 p.Ala462Gly missense_variant 0.42 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.41 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.35 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.35 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.35 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.43 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.42 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.45 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.46 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.5 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.51 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.58 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.61 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.64 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.61 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.64 pyrazinamide
clpC1 4039616 c.1089G>T synonymous_variant 0.65 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.63 pyrazinamide
clpC1 4039649 c.1056G>T synonymous_variant 0.6 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.56 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.53 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.58 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.57 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.57 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.55 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.52 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.53 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.5 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>C synonymous_variant 0.45 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.43 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.43 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.42 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.44 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.43 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.43 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.42 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.58 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 0.58 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.59 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4039925 c.780C>T synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.65 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 0.65 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.57 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.56 pyrazinamide
clpC1 4040056 p.Glu217Gln missense_variant 0.57 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.57 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.51 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.5 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.43 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.43 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.42 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.4 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.41 pyrazinamide
clpC1 4040195 c.510G>C synonymous_variant 0.37 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.37 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.34 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.33 pyrazinamide
clpC1 4040213 p.Ser164Asn missense_variant 0.33 pyrazinamide
clpC1 4040219 c.486C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040225 c.480A>T synonymous_variant 0.32 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.34 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.32 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.34 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.44 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 0.46 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.39 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 0.42 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.44 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.35 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.31 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.29 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.29 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.29 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.3 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 0.29 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.3 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.33 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.35 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.39 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.46 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.46 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.47 pyrazinamide
clpC1 4040441 c.264C>T synonymous_variant 0.48 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.5 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.52 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.52 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.51 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.61 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.62 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.55 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.55 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.54 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.55 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.53 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.53 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.52 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.52 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.51 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.52 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.51 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.49 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.44 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.41 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.41 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
panD 4044195 c.87T>C synonymous_variant 0.19 pyrazinamide
panD 4044210 c.72C>T synonymous_variant 0.19 pyrazinamide
panD 4044232 p.Cys17Tyr missense_variant 0.19 pyrazinamide
glpK 4138517 c.1239A>G synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138526 p.Asp410Glu missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138535 c.1221T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138538 c.1218C>T synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138565 c.1191G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138568 c.1188A>C synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138571 c.1185C>G synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138574 c.1182G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138577 c.1179G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138598 c.1158G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138601 c.1155G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138616 p.Ala380Val missense_variant 0.51 levofloxacin
moxifloxacin
isoniazid Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138622 c.1134C>G synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138625 c.1131G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138631 c.1125C>G synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>T synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138643 c.1113A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138658 c.1098C>G synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138670 c.1086G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138676 c.1080T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138682 c.1074C>T synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138696 p.Pro354Thr missense_variant 0.53 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138703 c.1051_1053delCGCinsAGG synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138724 c.1032A>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138727 c.1029C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138775 c.981C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138802 c.954G>C synonymous_variant 0.17 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139312 c.444T>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139318 c.438T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139321 c.435T>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139324 c.432A>G synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139339 c.417G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139348 c.408C>G synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139356 p.Leu134Val missense_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139359 p.Asn133Asp missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139360 c.396A>T synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139363 c.393T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139366 c.390T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139372 c.384A>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139375 c.381T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139384 p.Ser124Ala missense_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139387 c.369G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139408 c.348T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139417 c.339A>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139420 c.336T>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139431 p.Tyr109His missense_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139435 c.321C>G synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139440 c.316C>A synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139450 c.306G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139561 c.195G>A synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139576 c.180G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139585 c.171G>A synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139594 c.162C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139601 p.Arg52Lys missense_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139603 c.153C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4240717 c.855T>C synonymous_variant 0.28 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.36 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.35 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.35 ethambutol
embC 4240825 c.963G>A synonymous_variant 0.33 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.33 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.33 ethambutol
embC 4240855 c.993G>C synonymous_variant 0.19 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.2 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.2 ethambutol
embC 4241047 c.1185C>T synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embC 4241050 c.1188T>G synonymous_variant 0.2 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.18 ethambutol
embC 4241109 p.Ala416Gly missense_variant 0.18 ethambutol
embC 4241486 p.Leu542Val missense_variant 0.2 ethambutol
embC 4241494 c.1632C>G synonymous_variant 0.23 ethambutol
embC 4241500 c.1638A>T synonymous_variant 0.24 ethambutol
embC 4241509 c.1647A>G synonymous_variant 0.26 ethambutol
embC 4241513 p.Ser551Thr missense_variant 0.26 ethambutol
embC 4241516 c.1654_1656delTTAinsCTG synonymous_variant 0.27 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embC 4241533 c.1671T>C synonymous_variant 0.31 ethambutol
embC 4241536 c.1674A>C synonymous_variant 0.33 ethambutol
embC 4241545 c.1683T>C synonymous_variant 0.35 ethambutol
embC 4241548 c.1686T>A synonymous_variant 0.36 ethambutol
embC 4241551 c.1689A>C synonymous_variant 0.38 ethambutol
embC 4241560 c.1698C>G synonymous_variant 0.42 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.42 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.42 ethambutol
embC 4241591 c.1729_1731delCTCinsTTG synonymous_variant 0.44 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.39 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.37 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.35 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.3 ethambutol
embC 4241648 c.1786T>C synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embC 4241656 c.1794G>A synonymous_variant 0.26 ethambutol
embC 4241662 c.1800G>C synonymous_variant 0.25 ethambutol
embC 4241665 c.1803G>T synonymous_variant 0.25 ethambutol
embC 4241668 c.1806G>A synonymous_variant 0.23 ethambutol
embC 4241671 c.1809T>G synonymous_variant 0.22 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242803 p.Val981Leu missense_variant 0.99 ethambutol Not assoc w R
embA 4242832 c.-401A>G upstream_gene_variant 0.19 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.24 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.23 ethambutol
embC 4242847 c.2985C>G synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embA 4242862 c.-371A>G upstream_gene_variant 0.23 ethambutol
embC 4242872 p.Asp1004Thr missense_variant 0.24 ethambutol
embC 4242878 p.Thr1006Val missense_variant 0.24 ethambutol
embA 4242886 c.-347G>A upstream_gene_variant 0.23 ethambutol
embA 4242907 c.-326G>C upstream_gene_variant 0.25 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.25 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embA 4242940 c.-293T>C upstream_gene_variant 0.21 ethambutol
embC 4242941 p.His1027Tyr missense_variant 0.21 ethambutol
embC 4242944 p.Asn1028Leu missense_variant 0.21 ethambutol
embB 4245776 c.-738G>T upstream_gene_variant 0.21 ethambutol
embA 4245784 p.Thr851Lys missense_variant 0.25 ethambutol
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.24 ethambutol
embB 4245812 c.-702G>C upstream_gene_variant 0.24 ethambutol
embB 4245815 c.-699C>G upstream_gene_variant 0.24 ethambutol
embA 4245820 p.Ser863Thr missense_variant 0.25 ethambutol
embA 4245822 p.Pro864Ala missense_variant 0.25 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.19 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.23 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.27 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.32 ethambutol
embB 4247426 p.Gly305Gln missense_variant 0.39 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.41 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.41 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.42 ethambutol
embB 4247449 c.936C>T synonymous_variant 0.43 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.45 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.46 ethambutol
embB 4247488 c.975C>T synonymous_variant 0.51 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.53 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 0.56 ethambutol
embB 4247524 c.1011G>C synonymous_variant 0.54 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.52 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.39 ethambutol
embB 4247555 p.Leu348Ile missense_variant 0.38 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.36 ethambutol
embB 4247579 p.Ala356Ile missense_variant 0.35 ethambutol
embB 4247582 p.Ala357Cys missense_variant 0.35 ethambutol
embB 4247586 p.Gly358Ala missense_variant 0.35 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.34 ethambutol Not assoc w R - Interim
embB 4247593 c.1080G>C synonymous_variant 0.35 ethambutol
embB 4247626 c.1113C>G synonymous_variant 0.26 ethambutol
embB 4247974 c.1461C>G synonymous_variant 0.2 ethambutol
embB 4247977 c.1464C>G synonymous_variant 0.23 ethambutol
embB 4248011 p.Ser500Ala missense_variant 0.35 ethambutol
embB 4248020 c.1507T>C synonymous_variant 0.35 ethambutol
embB 4248025 c.1512A>G synonymous_variant 0.34 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.34 ethambutol
embB 4248040 c.1527C>T synonymous_variant 0.34 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.34 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.33 ethambutol
embB 4248063 p.Ala517Glu missense_variant 0.41 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.41 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.42 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.47 ethambutol
embB 4248106 c.1593C>G synonymous_variant 0.49 ethambutol
embB 4248127 c.1614G>C synonymous_variant 0.47 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.46 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.46 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.43 ethambutol
embB 4248143 p.Leu544Ile missense_variant 0.43 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.45 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.45 ethambutol
embB 4248167 p.Thr552Ala missense_variant 0.45 ethambutol
embB 4248170 p.Ala553Ser missense_variant 0.45 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.45 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.48 ethambutol
embB 4248202 c.1689T>C synonymous_variant 0.45 ethambutol
embB 4248203 p.Pro564Ala missense_variant 0.45 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.47 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 0.5 ethambutol
embB 4248225 p.Ala571Val missense_variant 0.5 ethambutol Uncertain significance
embB 4248242 p.Val577Ile missense_variant 0.46 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.42 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.32 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.3 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.23 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.17 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.19 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin