TB-Profiler result

Run: ERR9786843
Summary

Run ID: ERR9786843

Sample name:

Date: 2024-10-04T18:01:21.932406

Number of reads: 1706763

Percentage reads mapped: 59.78

Median coverage: 83.0

Strain:

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1.2 Euro-American None 0.98
lineage4.1.2.1 Euro-American (Haarlem) RD182 0.94
La1.2.BCG M.bovis None 0.1
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.29 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.33 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.22 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.29 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.31 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 582 c.582A>C synonymous_variant 0.22 isoniazid Not assoc w R - Interim
dnaA 591 c.591C>G synonymous_variant 0.22 isoniazid
dnaA 597 c.597C>G synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 609 c.609C>G synonymous_variant 0.22 isoniazid
dnaA 630 c.630C>G synonymous_variant 0.32 isoniazid
dnaA 636 c.636C>G synonymous_variant 0.34 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 652 c.652_654delCTAinsTTG synonymous_variant 0.36 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.36 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>G synonymous_variant 0.36 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.35 isoniazid
dnaA 693 c.693A>G synonymous_variant 0.36 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.37 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.38 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 753 c.753C>A synonymous_variant 0.39 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.38 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.38 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.38 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
dnaA 798 c.798C>T synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.36 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.35 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.33 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.31 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.31 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.32 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.32 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.33 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.34 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.28 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.26 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.3 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.28 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.28 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.31 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.31 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.3 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.27 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.27 isoniazid
dnaA 954 c.954G>C synonymous_variant 0.26 isoniazid
dnaA 957 c.957A>G synonymous_variant 0.25 isoniazid
dnaA 960 c.960C>G synonymous_variant 0.25 isoniazid
dnaA 963 c.963C>A synonymous_variant 0.25 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.25 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.25 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.25 isoniazid
dnaA 976 c.976C>T synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 996 c.996A>C synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 0.25 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 1029 c.1029C>T synonymous_variant 0.3 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 0.31 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.33 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 0.31 isoniazid Not assoc w R - Interim
dnaA 1056 c.1056G>C synonymous_variant 0.31 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.4 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.4 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 0.4 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.44 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.41 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.43 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.43 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 0.44 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.44 isoniazid
dnaA 1134 c.1134G>T synonymous_variant 0.43 isoniazid
dnaA 1140 c.1140C>G synonymous_variant 0.42 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.42 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.42 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.41 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 0.41 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.41 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.41 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.43 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.44 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.45 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.44 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.45 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.5 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.51 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>G synonymous_variant 0.48 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.45 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.43 isoniazid
dnaA 1312 c.1312_1314delCGAinsAGG synonymous_variant 0.37 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.36 isoniazid
dnaA 1329 c.1329A>G synonymous_variant 0.31 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.31 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 0.3 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 0.27 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.25 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 1374 c.1374G>A synonymous_variant 0.22 isoniazid
dnaA 1395 c.1395G>A synonymous_variant 0.21 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.25 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.23 isoniazid
gyrB 6085 c.846C>T synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.25 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.39 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.34 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6412 c.-890G>A upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 6440 p.Thr401Ala missense_variant 0.42 levofloxacin
moxifloxacin
gyrA 6448 c.-854G>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6451 c.-851A>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6457 c.-845T>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6475 c.-827C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6484 c.-818A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6490 c.-812T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6502 c.-800T>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6532 c.-770C>T upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6542 p.Ile435Leu missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6784 c.-518C>T upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.56 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 6838 c.-464C>T upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6853 c.-449A>G upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6865 c.-437G>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 6866 c.-436C>T upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6889 c.-413G>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.62 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>G upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 7057 c.-245C>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrA 7198 c.-104C>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7237 c.-65C>T upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7502 c.201C>T synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7538 c.237G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7655 c.354G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCTC synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7727 c.426G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7778 c.477G>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7841 c.540C>G synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8103 p.Ser268Ala missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 0.46 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8267 c.966G>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.58 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8576 c.1275C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8690 c.1389C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8708 c.1407G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.54 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Ser missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.56 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.56 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8817 p.Ser506Ala missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 8822 c.1521C>T synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8843 c.1542G>A synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8885 c.1584C>G synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9002 c.1701C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9065 c.1764C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>A synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 9212 c.1911G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9218 c.1917C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>G synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9260 c.1959G>A synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9365 c.2064G>A synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Tyr missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 9435 c.2134C>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9443 c.2142G>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9452 c.2151G>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9458 c.2157A>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9467 c.2166T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9485 c.2184A>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
Rv0010c 13780 c.-222C>G upstream_gene_variant 0.25 isoniazid
Rv0010c 13783 c.-225T>C upstream_gene_variant 0.25 isoniazid
Rv0010c 13786 c.-228C>G upstream_gene_variant 0.25 isoniazid
Rv0010c 13792 c.-234G>C upstream_gene_variant 0.26 isoniazid
Rv0010c 13801 c.-243T>C upstream_gene_variant 0.27 isoniazid
Rv0010c 13807 c.-249G>C upstream_gene_variant 0.27 isoniazid
Rv0010c 13810 c.-252A>C upstream_gene_variant 0.27 isoniazid
Rv0010c 13813 c.-255C>G upstream_gene_variant 0.27 isoniazid
Rv0010c 13816 c.-258C>G upstream_gene_variant 0.27 isoniazid
Rv0010c 13819 c.-261A>G upstream_gene_variant 0.27 isoniazid
Rv0010c 13825 c.-267C>G upstream_gene_variant 0.28 isoniazid
Rv0010c 13828 c.-272_-270delATTinsGTC upstream_gene_variant 0.29 isoniazid
Rv0010c 13834 c.-276A>C upstream_gene_variant 0.3 isoniazid
Rv0010c 13843 c.-285T>C upstream_gene_variant 0.31 isoniazid
Rv0010c 13852 c.-296_-294delTTAinsCTG upstream_gene_variant 0.3 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 0.31 isoniazid
Rv0010c 13864 c.-306A>C upstream_gene_variant 0.31 isoniazid
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.34 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.27 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.26 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.28 isoniazid
fgd1 490782 c.-1G>C upstream_gene_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 490797 c.15G>A synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 490800 c.18A>C synonymous_variant 0.24 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 490818 c.36C>T synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 490827 c.45C>T synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 490851 c.69A>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 490854 c.72C>T synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 490868 p.Ala29Gly missense_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 490902 c.120T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 490917 c.135C>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 490921 p.Gln47Glu missense_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 490929 c.147C>A synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 490932 c.150T>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 490947 c.165G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fgd1 490948 p.Ser56Ala missense_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 490959 c.177C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 490962 c.180T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 490971 c.189A>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 490980 p.Asn66Lys missense_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 490981 c.199C>A synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 490987 p.Leu69Val missense_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491034 c.252C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fgd1 491058 c.276C>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491064 c.282A>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 491070 c.288G>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 491076 c.294G>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491077 p.Asn99Asp missense_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491110 p.Ala110Ser missense_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491124 c.342C>A synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491133 c.351A>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491163 c.381G>A synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491168 p.Phe129Tyr missense_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>T synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.29 pretomanid
delamanid
clofazimine
fgd1 491213 p.Ser144Ile missense_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491591 p.Lys270Met missense_variant 0.95 pretomanid
delamanid Uncertain significance
clofazimine Not assoc w R
mshA 575515 c.168G>A synonymous_variant 0.22 isoniazid
ethionamide
mshA 575521 c.174A>C synonymous_variant 0.25 isoniazid
ethionamide
mshA 575527 c.180G>C synonymous_variant 0.26 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 0.26 isoniazid
ethionamide
mshA 575542 c.195C>G synonymous_variant 0.27 isoniazid
ethionamide
mshA 575560 c.213C>T synonymous_variant 0.25 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 0.27 isoniazid
ethionamide
mshA 575569 c.222A>G synonymous_variant 0.26 isoniazid
ethionamide
mshA 575571 p.Ser75Thr missense_variant 0.26 isoniazid
ethionamide
mshA 575587 c.240C>G synonymous_variant 0.26 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 0.26 isoniazid
ethionamide
mshA 575593 c.246G>C synonymous_variant 0.27 isoniazid
ethionamide
mshA 575617 c.270C>G synonymous_variant 0.33 isoniazid
ethionamide
mshA 575623 c.276C>G synonymous_variant 0.32 isoniazid
ethionamide
mshA 575629 c.282A>C synonymous_variant 0.33 isoniazid
ethionamide
mshA 575635 c.288A>C synonymous_variant 0.31 isoniazid Not assoc w R - Interim
ethionamide
mshA 575638 c.291T>C synonymous_variant 0.31 isoniazid
ethionamide
mshA 575641 c.294A>G synonymous_variant 0.3 isoniazid
ethionamide
mshA 575647 c.300G>C synonymous_variant 0.3 isoniazid
ethionamide
mshA 575649 p.Val101Ala missense_variant 0.31 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.38 isoniazid
ethionamide
mshA 575674 c.327G>C synonymous_variant 0.42 isoniazid
ethionamide
mshA 575679 p.Asn111Ser missense_variant 0.58 isoniazid Not assoc w R
ethionamide Not assoc w R
mshA 575692 c.345G>C synonymous_variant 0.44 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.44 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 0.41 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.42 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.44 isoniazid
ethionamide
mshA 575722 c.375G>C synonymous_variant 0.42 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 0.41 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.42 isoniazid
ethionamide
mshA 575746 c.399C>T synonymous_variant 0.43 isoniazid
ethionamide
mshA 575770 c.423G>A synonymous_variant 0.36 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 0.36 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.37 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.36 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.37 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.39 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 0.38 isoniazid
ethionamide
mshA 575833 c.486C>T synonymous_variant 0.4 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575845 c.498C>G synonymous_variant 0.37 isoniazid
ethionamide
mshA 575860 c.513G>A synonymous_variant 0.36 isoniazid
ethionamide
mshA 575878 c.531A>C synonymous_variant 0.33 isoniazid
ethionamide
mshA 575887 c.540G>C synonymous_variant 0.34 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.34 isoniazid
ethionamide
mshA 575896 c.549G>C synonymous_variant 0.33 isoniazid
ethionamide
mshA 575908 c.561A>G synonymous_variant 0.3 isoniazid
ethionamide
mshA 575917 p.Asp190Glu missense_variant 0.29 isoniazid
ethionamide
mshA 575920 c.573C>G synonymous_variant 0.28 isoniazid
ethionamide
mshA 575923 p.Gly193Ser missense_variant 0.28 isoniazid
ethionamide
mshA 575938 c.591G>C synonymous_variant 0.26 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.27 isoniazid
ethionamide
mshA 575953 c.606G>C synonymous_variant 0.28 isoniazid
ethionamide
mshA 575980 c.633T>C synonymous_variant 0.24 isoniazid
ethionamide
mshA 575984 c.637T>C synonymous_variant 0.25 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 619513 c.-378G>C upstream_gene_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 619525 c.-366C>T upstream_gene_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 619531 c.-360T>C upstream_gene_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 619534 c.-357G>A upstream_gene_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 619535 c.-356_-354delCAAinsTCG upstream_gene_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 619543 c.-348C>G upstream_gene_variant 0.34 kanamycin
capreomycin
amikacin
ccsA 619552 c.-339A>G upstream_gene_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 619555 c.-336C>G upstream_gene_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 619558 c.-333G>C upstream_gene_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 619574 c.-317G>A upstream_gene_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 619594 c.-297G>C upstream_gene_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 619597 c.-294G>C upstream_gene_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 619618 c.-273C>G upstream_gene_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 619627 c.-264C>G upstream_gene_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>A upstream_gene_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 619645 c.-246G>C upstream_gene_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>T upstream_gene_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 619676 c.-215C>G upstream_gene_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 620198 p.Gln103Leu missense_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620226 c.336G>A synonymous_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620265 c.375C>G synonymous_variant 0.34 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>C synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.34 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>G synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.3 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv0565c 656325 c.1146C>G synonymous_variant 0.25 ethionamide
Rv0565c 656349 c.1122G>A synonymous_variant 0.3 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.29 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 0.3 ethionamide
Rv0565c 656367 c.1101_1104delTCGGinsGC frameshift_variant&synonymous_variant 0.3 ethionamide Uncertain significance
Rv0565c 656371 p.Pro367His missense_variant 0.3 ethionamide
Rv0565c 656375 c.1095_1096insAA frameshift_variant 0.3 ethionamide Uncertain significance
Rv0565c 656383 p.Val363Thr missense_variant 0.31 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.37 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.39 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.39 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.37 ethionamide
Rv0565c 656430 c.1041C>G synonymous_variant 0.37 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 0.36 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.36 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.36 ethionamide
Rv0565c 656466 c.1005G>A synonymous_variant 0.37 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.38 ethionamide
Rv0565c 656478 c.993C>G synonymous_variant 0.37 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 0.37 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.37 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.37 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.38 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.38 ethionamide
Rv0565c 656506 p.Asp322Gly missense_variant 0.38 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.37 ethionamide Not assoc w R - Interim
Rv0565c 656534 p.Arg313Gly missense_variant 0.36 ethionamide
Rv0565c 656538 p.Ser311Ala missense_variant 0.35 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 0.28 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 0.37 ethionamide
Rv0565c 657056 p.Val139Leu missense_variant 0.33 ethionamide
Rv0565c 657060 c.411G>C synonymous_variant 0.32 ethionamide
Rv0565c 657064 p.Ser136Ala missense_variant 0.33 ethionamide
Rv0565c 657072 p.His133Leu missense_variant 0.32 ethionamide
Rv0565c 657079 p.His131Arg missense_variant 0.34 ethionamide
Rv0565c 657081 p.Val130Ala missense_variant 0.34 ethionamide
Rv0565c 657087 p.Asn128Asp missense_variant 0.33 ethionamide
Rv0565c 657098 p.Phe125Val missense_variant 0.4 ethionamide
Rv0565c 657105 c.366C>G synonymous_variant 0.43 ethionamide
Rv0565c 657114 c.357T>C synonymous_variant 0.42 ethionamide Not assoc w R - Interim
Rv0565c 657122 p.Ser117Ala missense_variant 0.49 ethionamide
Rv0565c 657123 c.348A>C synonymous_variant 0.49 ethionamide
Rv0565c 657138 p.Ala111Ser missense_variant 0.49 ethionamide
Rv0565c 657144 c.327T>G synonymous_variant 0.51 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 0.56 ethionamide
Rv0565c 657168 c.303C>G synonymous_variant 0.52 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 0.51 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 0.54 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.54 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.54 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 0.54 ethionamide Uncertain significance
Rv0565c 657201 c.270C>G synonymous_variant 0.54 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.54 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.54 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.54 ethionamide
Rv0565c 657241 p.Glu77Arg missense_variant 0.56 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.48 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.47 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.44 ethionamide
Rv0565c 657267 p.Ser68Pro missense_variant 0.44 ethionamide Uncertain significance
Rv0565c 657291 c.180C>G synonymous_variant 0.4 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.4 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.33 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.28 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.28 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.27 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.24 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.22 ethionamide
Rv0565c 657653 c.-183C>G upstream_gene_variant 0.24 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.3 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.28 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.34 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.36 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.37 ethionamide
hadA 732270 p.Glu114Val missense_variant 0.22 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.22 isoniazid
hadA 732280 c.351C>T synonymous_variant 0.28 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.33 isoniazid
hadA 732304 c.375C>T synonymous_variant 0.31 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.32 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.34 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.41 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.43 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.49 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.47 isoniazid
hadA 732355 c.426G>C synonymous_variant 0.53 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.58 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.6 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.57 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.57 isoniazid
nusG 734123 c.-131C>T upstream_gene_variant 0.23 rifampicin
nusG 734135 c.-119G>T upstream_gene_variant 0.22 rifampicin
nusG 734144 c.-110G>T upstream_gene_variant 0.24 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.24 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 0.24 rifampicin
nusG 734176 c.-78_-77delGTinsTG upstream_gene_variant 0.24 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 0.24 rifampicin Uncertain significance
nusG 734186 c.-68G>C upstream_gene_variant 0.26 rifampicin Uncertain significance
nusG 734407 p.Val52Ile missense_variant 0.23 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.25 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.24 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.26 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.28 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.32 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>C synonymous_variant 0.32 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.3 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
nusG 734538 c.285C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.36 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.35 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.38 rifampicin
nusG 734596 c.343_345delTTGinsCTC synonymous_variant 0.33 rifampicin
nusG 734604 c.351C>T synonymous_variant 0.31 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.32 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.3 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.27 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.24 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.24 rifampicin
nusG 734646 c.393G>C synonymous_variant 0.24 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.23 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.24 rifampicin
nusG 734667 c.414C>T synonymous_variant 0.23 rifampicin
nusG 734670 c.417G>T synonymous_variant 0.23 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.24 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734680 p.Ala143Thr missense_variant 0.24 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.21 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.25 rifampicin
nusG 734750 p.Ser166Thr missense_variant 0.22 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.23 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.3 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.32 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.43 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.56 rifampicin Not assoc w R
rpoB 760118 c.312T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.48 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.48 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.63 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 0.64 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 0.65 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.65 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.66 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.66 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.66 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.64 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.61 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760520 c.714C>G synonymous_variant 0.65 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.65 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.64 rifampicin
rpoB 760547 c.741G>T synonymous_variant 0.66 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.66 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.63 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.57 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.59 rifampicin
rpoB 760755 p.His317Asn missense_variant 0.58 rifampicin
rpoB 760765 p.Glu320Ala missense_variant 0.57 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.57 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.58 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.58 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.53 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.54 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.54 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.52 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 0.5 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.48 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.48 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.45 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.45 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.44 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.47 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.5 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.58 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>G synonymous_variant 0.62 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.67 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.67 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.65 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.5 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.5 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761361 c.1555_1556delAGinsTC synonymous_variant 0.47 rifampicin
rpoB 761373 p.Val523His missense_variant 0.45 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.51 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.5 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.44 rifampicin
rpoB 761437 p.Ala544Asp missense_variant 0.44 rifampicin
rpoB 761439 p.Asp545Lys missense_variant 0.44 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.44 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.44 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.44 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.45 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.49 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.49 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.49 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.49 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.52 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.54 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.55 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.51 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.5 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>T synonymous_variant 0.54 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.53 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.52 rifampicin
rpoB 761699 c.1893C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761711 c.1905C>G synonymous_variant 0.48 rifampicin
rpoB 761714 c.1908C>G synonymous_variant 0.48 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 0.48 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.48 rifampicin
rpoB 761735 c.1929C>G synonymous_variant 0.5 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.5 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.5 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.47 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.44 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.44 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.41 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.42 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.43 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.45 rifampicin
rpoB 761846 c.2040G>A synonymous_variant 0.41 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.41 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.43 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.44 rifampicin
rpoB 761867 c.2061C>G synonymous_variant 0.43 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 0.44 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.44 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.44 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.47 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.46 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.44 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.43 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.43 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.43 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.47 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.51 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 0.5 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.48 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762074 c.2268C>G synonymous_variant 0.51 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.52 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.56 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.58 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.62 rifampicin
rpoB 762284 c.2478G>T synonymous_variant 0.61 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.61 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.61 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.62 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.62 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.55 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.54 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.59 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.58 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.57 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.53 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.48 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.48 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.48 rifampicin Uncertain significance
rpoC 762533 c.-837T>C upstream_gene_variant 0.41 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.41 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.41 rifampicin
rpoC 762545 c.-825C>G upstream_gene_variant 0.45 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.44 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.24 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 0.29 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.31 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.32 rifampicin Uncertain significance
rpoB 762795 p.Asp997Asn missense_variant 0.32 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 0.33 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.38 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 762863 c.-507T>G upstream_gene_variant 0.48 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>G upstream_gene_variant 0.61 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.6 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.59 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.52 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.49 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.47 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>C upstream_gene_variant 0.34 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.33 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.33 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.34 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.22 rifampicin
rpoC 763402 c.33C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.28 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.41 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.46 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.52 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.56 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763714 c.345G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.57 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.6 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.6 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.61 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.64 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.62 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.61 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.6 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.59 rifampicin
rpoC 763852 c.483C>G synonymous_variant 0.56 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.56 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.56 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.59 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.59 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.6 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.61 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.62 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763930 c.561G>A synonymous_variant 0.6 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.63 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.58 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.56 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.55 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.55 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.54 rifampicin
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.5 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.52 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.5 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.49 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.52 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.5 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.42 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.46 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.46 rifampicin
rpoC 764134 c.765C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764198 c.829C>T synonymous_variant 0.48 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.5 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764213 p.Arg282Lys missense_variant 0.46 rifampicin Uncertain significance
rpoC 764257 c.888G>C synonymous_variant 0.48 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.53 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.54 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 0.52 rifampicin
rpoC 764293 c.924G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.55 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.53 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.54 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.53 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.62 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.64 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.66 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.67 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>C synonymous_variant 0.62 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.62 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.59 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.59 rifampicin
rpoC 764647 c.1278C>T synonymous_variant 0.6 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.64 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.6 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.6 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.6 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.52 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.36 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.35 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.35 rifampicin
rpoC 765150 p.Gly594Glu missense_variant 1.0 rifampicin Not assoc w R
rpoC 765300 p.Val644Ala missense_variant 0.25 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.28 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.29 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765361 c.1992C>A synonymous_variant 0.33 rifampicin
rpoC 765370 c.2001G>T synonymous_variant 0.35 rifampicin
rpoC 765371 c.2002C>T synonymous_variant 0.35 rifampicin
rpoC 765379 c.2010G>T synonymous_variant 0.38 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.38 rifampicin Uncertain significance
rpoC 765394 c.2025G>A synonymous_variant 0.39 rifampicin
rpoC 765404 p.Leu679Val missense_variant 0.4 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.39 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.41 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.52 rifampicin
rpoC 765452 p.Ala695Ser missense_variant 0.52 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.54 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.57 rifampicin
rpoC 765550 c.2181C>T synonymous_variant 0.56 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.56 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.54 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.56 rifampicin
rpoC 765583 c.2214G>C synonymous_variant 0.57 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.57 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.54 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.56 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.56 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.56 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.6 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 0.59 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.59 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.59 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.59 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.57 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 0.58 rifampicin
rpoC 765928 c.2559C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>G synonymous_variant 0.54 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.42 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.45 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.45 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.45 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.4 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.39 rifampicin
rpoC 766080 c.2712_2715delTGCA frameshift_variant 0.35 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.36 rifampicin
rpoC 766097 p.Leu910Val missense_variant 0.37 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.3 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.26 rifampicin
rpoC 766147 c.2778C>T synonymous_variant 0.24 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.25 rifampicin Uncertain significance
rpoC 766280 p.Ser971Gly missense_variant 0.23 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.28 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.28 rifampicin
rpoC 766327 c.2958C>G synonymous_variant 0.31 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.33 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.33 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.34 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.36 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.41 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.43 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.43 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 766411 c.3042C>G synonymous_variant 0.44 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.49 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.57 rifampicin
rpoC 766462 c.3093G>T synonymous_variant 0.55 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.54 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.53 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.58 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766513 c.3144C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>G synonymous_variant 0.65 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.65 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.66 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.62 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.59 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.61 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.61 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.65 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.61 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.58 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.58 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.58 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.59 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.59 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.59 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.58 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.58 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.58 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.59 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.59 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.6 rifampicin
rpoC 766918 c.3549C>G synonymous_variant 0.62 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 0.62 rifampicin
rpoC 766924 p.Glu1185Asp missense_variant 0.62 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.62 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 0.65 rifampicin
rpoC 766987 c.3618G>C synonymous_variant 0.65 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767032 c.3663G>A synonymous_variant 0.64 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.66 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.64 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.63 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.56 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.47 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775834 p.Ala883Ser missense_variant 0.22 bedaquiline
clofazimine
mmpL5 775835 c.2646C>A synonymous_variant 0.22 bedaquiline
clofazimine
mmpL5 775847 c.2634G>T synonymous_variant 0.25 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 0.25 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.25 bedaquiline
clofazimine
mmpL5 775864 p.Ala873Ser missense_variant 0.25 bedaquiline
clofazimine
mmpL5 775865 c.2616T>G synonymous_variant 0.25 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.26 bedaquiline
clofazimine
mmpL5 775886 c.2595A>C synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.28 bedaquiline
clofazimine
mmpL5 775913 c.2568C>G synonymous_variant 0.26 bedaquiline
clofazimine
rpsL 781128 c.-432C>G upstream_gene_variant 0.31 streptomycin
rpsL 781134 c.-426T>C upstream_gene_variant 0.29 streptomycin
rpsL 781138 c.-422_-421delCAinsGC upstream_gene_variant 0.28 streptomycin
rpsL 781143 c.-417T>G upstream_gene_variant 0.29 streptomycin
rpsL 781147 c.-413T>C upstream_gene_variant 0.29 streptomycin
rpsL 781153 c.-407G>T upstream_gene_variant 0.29 streptomycin
rpsL 781158 c.-402C>G upstream_gene_variant 0.28 streptomycin
rpsL 781164 c.-396T>C upstream_gene_variant 0.28 streptomycin
rpsL 781170 c.-390G>C upstream_gene_variant 0.3 streptomycin
rpsL 781173 c.-387A>G upstream_gene_variant 0.3 streptomycin
rpsL 781179 c.-381T>C upstream_gene_variant 0.3 streptomycin
rpsL 781182 c.-378G>C upstream_gene_variant 0.3 streptomycin
rpsL 781188 c.-372G>T upstream_gene_variant 0.3 streptomycin
rpsL 781197 c.-363A>G upstream_gene_variant 0.28 streptomycin
rpsL 781209 c.-351C>G upstream_gene_variant 0.27 streptomycin
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.2 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.24 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.24 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.35 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.38 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.38 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.46 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.5 streptomycin
rpsL 781718 c.159C>T synonymous_variant 0.51 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.51 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.53 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.57 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.57 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.58 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.72 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.69 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.7 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.72 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.72 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.72 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.73 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.72 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.72 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.73 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.71 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.65 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.63 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.25 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.31 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.31 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.34 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.36 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.33 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.35 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.36 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.41 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.43 linezolid
rplC 800703 c.-106_-104delTTGinsCTC upstream_gene_variant 0.43 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.44 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.43 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.44 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.46 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.5 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.5 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.5 linezolid
rplC 800798 c.-11T>C upstream_gene_variant 0.41 linezolid
rplC 800801 c.-8_-6delACAinsC upstream_gene_variant 0.42 linezolid
rplC 800806 c.-3G>C upstream_gene_variant 0.41 linezolid
rplC 800807 c.-2C>T upstream_gene_variant 0.41 linezolid
rplC 800808 c.-1A>C upstream_gene_variant 0.4 linezolid Uncertain significance
rplC 800815 c.7C>A synonymous_variant 0.41 linezolid
rplC 800820 c.12G>A synonymous_variant 0.43 linezolid
rplC 800829 c.21C>G synonymous_variant 0.44 linezolid
rplC 800844 c.36T>C synonymous_variant 0.43 linezolid
rplC 800856 c.48A>G synonymous_variant 0.45 linezolid
rplC 800865 c.57A>G synonymous_variant 0.44 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.43 linezolid
rplC 800872 c.64_66delAGAinsCGG synonymous_variant 0.41 linezolid
rplC 800877 c.69A>C synonymous_variant 0.39 linezolid
rplC 800880 c.72A>G synonymous_variant 0.39 linezolid
rplC 800889 c.81C>G synonymous_variant 0.42 linezolid
rplC 800892 c.84G>C synonymous_variant 0.42 linezolid
rplC 800904 c.96G>C synonymous_variant 0.41 linezolid
rplC 800907 c.99C>G synonymous_variant 0.41 linezolid
rplC 800916 c.108A>G synonymous_variant 0.42 linezolid
rplC 800922 c.114C>G synonymous_variant 0.42 linezolid
rplC 800928 c.120C>T synonymous_variant 0.41 linezolid
rplC 800931 c.123G>C synonymous_variant 0.39 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.38 linezolid
rplC 800946 c.138T>C synonymous_variant 0.36 linezolid
rplC 800949 c.141T>C synonymous_variant 0.38 linezolid
rplC 800970 c.162T>C synonymous_variant 0.41 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.39 linezolid
rplC 800985 c.177A>C synonymous_variant 0.38 linezolid
rplC 801004 p.Leu66Val missense_variant 0.33 linezolid
rplC 801009 c.201A>C synonymous_variant 0.33 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.33 linezolid
rplC 801027 c.219C>G synonymous_variant 0.3 linezolid
rplC 801033 c.225C>G synonymous_variant 0.29 linezolid
rplC 801039 c.231A>G synonymous_variant 0.3 linezolid
rplC 801045 c.237A>C synonymous_variant 0.29 linezolid
rplC 801047 p.Tyr80Phe missense_variant 0.28 linezolid
rplC 801054 c.246G>C synonymous_variant 0.28 linezolid
rplC 801069 p.Asp87Glu missense_variant 0.28 linezolid
rplC 801070 p.Asp88Asn missense_variant 0.26 linezolid
rplC 801073 p.Ser89Pro missense_variant 0.27 linezolid
rplC 801078 p.Asp90Glu missense_variant 0.27 linezolid
rplC 801084 c.276G>C synonymous_variant 0.27 linezolid
rplC 801085 p.Thr93Ala missense_variant 0.26 linezolid Uncertain significance
rplC 801094 p.Gln96Glu missense_variant 0.24 linezolid
rplC 801099 c.291T>C synonymous_variant 0.25 linezolid
rplC 801102 c.294G>C synonymous_variant 0.25 linezolid
rplC 801114 c.306C>G synonymous_variant 0.24 linezolid
rplC 801132 c.324T>C synonymous_variant 0.28 linezolid
rplC 801136 p.Ser110Ala missense_variant 0.28 linezolid
rplC 801147 c.339T>C synonymous_variant 0.3 linezolid
rplC 801150 c.342G>C synonymous_variant 0.3 linezolid
rplC 801156 c.348T>C synonymous_variant 0.33 linezolid
rplC 801171 c.363A>G synonymous_variant 0.43 linezolid
rplC 801174 c.366T>C synonymous_variant 0.41 linezolid
rplC 801195 c.387G>C synonymous_variant 0.41 linezolid
rplC 801207 c.399C>T synonymous_variant 0.41 linezolid
rplC 801210 c.402T>C synonymous_variant 0.42 linezolid
rplC 801222 c.414T>C synonymous_variant 0.41 linezolid
rplC 801225 c.417C>T synonymous_variant 0.39 linezolid
rplC 801249 c.441T>C synonymous_variant 0.42 linezolid
rplC 801255 c.447C>T synonymous_variant 0.44 linezolid
rplC 801267 c.459A>T synonymous_variant 0.44 linezolid
rplC 801270 c.462T>C synonymous_variant 0.43 linezolid
rplC 801276 c.468G>C synonymous_variant 0.44 linezolid
rplC 801282 c.474G>C synonymous_variant 0.46 linezolid
rplC 801307 p.Ala167Ser missense_variant 0.44 linezolid
rplC 801312 c.504G>C synonymous_variant 0.44 linezolid
rplC 801321 c.513C>T synonymous_variant 0.43 linezolid Not assoc w R - Interim
rplC 801323 p.Asn172Ser missense_variant 0.43 linezolid
rplC 801327 c.519C>T synonymous_variant 0.42 linezolid
rplC 801330 c.522G>C synonymous_variant 0.42 linezolid
rplC 801339 c.531T>C synonymous_variant 0.43 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.43 linezolid
rplC 801348 c.540T>G synonymous_variant 0.44 linezolid
rplC 801357 c.549T>C synonymous_variant 0.45 linezolid
rplC 801396 c.588T>C synonymous_variant 0.45 linezolid
rplC 801402 c.594T>C synonymous_variant 0.44 linezolid
rplC 801405 c.597T>C synonymous_variant 0.43 linezolid
rplC 801423 c.615G>C synonymous_variant 0.39 linezolid
rplC 801427 p.Met207Val missense_variant 0.39 linezolid
rplC 801438 c.630T>C synonymous_variant 0.42 linezolid
rplC 801442 p.Ile212Val missense_variant 0.41 linezolid
fbiC 1303455 c.525C>G synonymous_variant 0.24 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303480 p.Gln184Glu missense_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1303488 c.558G>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1303492 c.562T>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1303554 c.624G>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1303581 c.651G>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>T synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303647 c.717G>T synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303661 p.Val244Ala missense_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303674 c.744C>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303677 c.747C>A synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303727 p.Thr266Asn missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Thr missense_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 0.49 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>T synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303788 c.858T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303794 c.864A>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303890 c.960G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303897 c.967C>T synonymous_variant 0.49 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303905 c.975G>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303908 c.978C>A synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303914 c.984C>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303923 c.993C>T synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303932 c.1002G>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1303935 c.1005G>T synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303956 c.1026A>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303969 p.Val347Ile missense_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>A synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1303986 c.1056C>T synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304001 c.1071C>T synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304034 c.1104A>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304040 c.1110C>G synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304046 c.1116C>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304050 c.1120T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304058 p.Glu376Asp missense_variant 0.3 pretomanid
delamanid Uncertain significance
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304070 c.1140C>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304079 c.1149A>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304091 p.Asp387Glu missense_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304097 c.1167G>T synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304115 c.1185A>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304137 p.Ala403Ser missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304161 p.Arg411Ala missense_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304169 c.1239T>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304173 p.Val415Thr missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304205 c.1275C>T synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304208 c.1278C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304545 p.Val539Thr missense_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304574 c.1644C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Glu missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>A synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>T synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304711 p.Ala594Glu missense_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.59 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304796 c.1866G>A synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304853 c.1923C>T synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304880 c.1950C>T synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304925 c.1995G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304955 c.2025G>A synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304970 c.2040G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304995 c.2065T>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305012 c.2082G>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1305014 p.Thr695Ser missense_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>A synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1305039 c.2109G>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305045 c.2115A>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1305066 c.2136T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1305069 c.2139G>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1305075 c.2145T>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305078 c.2148A>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1305092 p.Ala721Gly missense_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1305096 c.2166T>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1305114 c.2184T>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1305117 c.2187T>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 0.27 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1305144 c.2214G>A synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1305150 c.2220C>A synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1305173 p.Asn748Ser missense_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1305181 c.2251T>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305186 c.2256C>T synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1305195 c.2265T>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1305199 p.Ala757Ser missense_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1305215 p.Ser762Thr missense_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1305231 c.2301C>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1305237 c.2307A>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305240 c.2310T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305243 c.2313T>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305244 c.2314T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305249 c.2319G>T synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305273 c.2343C>T synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305276 c.2346G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305279 p.His783Gln missense_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305282 c.2352T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305297 c.2367G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305300 c.2370A>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305303 c.2373T>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1305306 c.2376A>T synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305309 c.2379G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305310 p.Arg794Glu missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305318 c.2388C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1305331 p.Glu801Asn missense_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1305400 p.His824Tyr missense_variant 0.19 pretomanid
delamanid
clofazimine
sigE 1364727 c.315C>T synonymous_variant 0.21 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.26 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.25 pyrazinamide
sigE 1364767 c.355_357delAGGinsCGT synonymous_variant 0.26 pyrazinamide
sigE 1364772 c.360G>C synonymous_variant 0.3 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.36 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.37 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.42 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.41 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.42 pyrazinamide
sigE 1364818 c.406_408delCTAinsTTG synonymous_variant 0.43 pyrazinamide
sigE 1364835 c.423C>G synonymous_variant 0.48 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.51 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.49 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.47 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 0.46 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.46 pyrazinamide
sigE 1364866 p.Ala152Ser missense_variant 0.46 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.47 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.44 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.44 pyrazinamide
sigE 1364910 c.498G>T synonymous_variant 0.46 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.47 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 0.41 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.41 pyrazinamide
sigE 1364961 c.549A>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.38 pyrazinamide
sigE 1364980 c.568_570delTTGinsCTC synonymous_variant 0.38 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.39 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
sigE 1365015 c.603G>C synonymous_variant 0.29 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.29 pyrazinamide
Rv1258c 1407079 c.261delC frameshift_variant 1.0 streptomycin Uncertain significance
pyrazinamide Uncertain significance
isoniazid Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.29 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.4 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.4 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.39 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.4 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.42 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.42 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.46 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.51 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.39 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1473752 n.95G>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473936 n.279A>G non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1473966 n.309T>C non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.59 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474036 n.379G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1474288 n.632_634delCTT non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475201 n.1544G>A non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475409 n.1752T>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.55 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475758 n.2104delC non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.46 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476030 n.2373_2377delACCTCinsGTACA non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.45 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1476717 n.3060C>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
inhA 1673547 c.-655T>C upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673568 c.-634C>G upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673569 c.-633G>A upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673574 c.-628C>G upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673580 c.-622T>C upstream_gene_variant 0.3 isoniazid Uncertain significance
ethionamide
inhA 1673589 c.-613A>G upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673595 c.-607A>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673596 c.-606A>G upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673601 c.-601G>A upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673607 c.-595T>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673610 c.-592C>T upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673616 c.-586A>G upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673619 c.-583T>C upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673625 c.-577C>G upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673633 c.-569G>A upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673641 c.-561G>A upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673646 c.-556T>C upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673657 c.-545_-544delCGinsAA upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 0.33 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673682 c.-520G>C upstream_gene_variant 0.34 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsAA upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673733 c.-469G>C upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673758 c.-444A>C upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1673797 c.-405_-403delGCTinsACC upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673805 c.-397G>C upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673808 c.-394A>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673809 c.-393T>G upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673823 c.-378_-376delCGC upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673829 c.-373C>G upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673832 c.-370delAinsGCGG upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673841 c.-361A>G upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673844 c.-358G>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673849 c.-353T>A upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673853 c.-349A>C upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673856 c.-346T>C upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673886 c.-316C>T upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673890 c.-312G>T upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673901 c.-301A>C upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.39 isoniazid
ethionamide
inhA 1673916 c.-286A>T upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1673917 c.-285_-283delGTGinsCTC upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1673934 c.-268C>T upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673941 c.-261_-259delGCCinsTCG upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673946 c.-256C>G upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673962 c.-240_-238delAACinsGGG upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1673985 c.-217C>G upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673988 c.-214G>C upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1674037 c.-165_-163delCAGinsGCC upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1674049 c.-153_-151delCAAinsGAC upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1674084 c.-118C>G upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1674114 c.-88T>G upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1674123 c.-79T>C upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1674129 c.-73C>T upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1674136 c.-66T>G upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1674159 c.-43C>T upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1674171 c.-31T>C upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1674177 c.-25C>T upstream_gene_variant 0.28 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674184 c.-18_-17insTTCA upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1674187 c.-15A>C upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1674190 c.-12_-11delACinsGAGGACATT upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1674199 c.-3C>G upstream_gene_variant 0.38 isoniazid Uncertain significance
ethionamide
inhA 1674205 p.Thr2Ala missense_variant 0.41 isoniazid Uncertain significance
ethionamide
inhA 1674216 c.15G>C synonymous_variant 0.41 isoniazid
ethionamide
inhA 1674235 p.Val12Ile missense_variant 0.34 isoniazid Uncertain significance
ethionamide
inhA 1674238 c.37_39delAGCinsTCG synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674243 c.42A>G synonymous_variant 0.3 isoniazid
ethionamide
inhA 1674255 c.54C>T synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674279 c.78A>C synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674280 p.Arg27Lys missense_variant 0.27 isoniazid
ethionamide
inhA 1674284 p.Val28Ala missense_variant 0.27 isoniazid
ethionamide
inhA 1674295 p.Gln32Ala missense_variant 0.25 isoniazid
ethionamide
inhA 1674300 c.99C>T synonymous_variant 0.26 isoniazid
ethionamide
inhA 1674303 c.102C>G synonymous_variant 0.28 isoniazid
ethionamide
inhA 1674307 c.106C>T synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674315 c.114C>G synonymous_variant 0.34 isoniazid
ethionamide
inhA 1674324 c.123C>T synonymous_variant 0.38 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674331 c.130C>T synonymous_variant 0.41 isoniazid
ethionamide
inhA 1674336 c.135G>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674352 p.Thr51Ala missense_variant 0.45 isoniazid
ethionamide Uncertain significance
inhA 1674368 p.Ala56Glu missense_variant 0.41 isoniazid
ethionamide
inhA 1674375 c.174C>G synonymous_variant 0.38 isoniazid
ethionamide
inhA 1674382 p.Leu61Ile missense_variant 0.34 isoniazid
ethionamide
inhA 1674387 c.186A>G synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674399 c.198A>G synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674414 c.214_216delGCC conservative_inframe_deletion 0.37 isoniazid
ethionamide
inhA 1674419 p.Ser73Asn missense_variant 0.37 isoniazid
ethionamide
inhA 1674422 c.221_222delTGinsCGCTC missense_variant&conservative_inframe_insertion 0.37 isoniazid
ethionamide
inhA 1674428 p.Gly76Glu missense_variant 0.37 isoniazid
ethionamide
inhA 1674433 p.Val78Ile missense_variant 0.38 isoniazid
ethionamide
inhA 1674438 c.237C>G synonymous_variant 0.37 isoniazid
ethionamide
inhA 1674440 p.Glu80Ala missense_variant 0.37 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674443 p.Ala81Glu missense_variant 0.36 isoniazid
ethionamide
inhA 1674450 c.249G>C synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674452 p.Ala84Glu missense_variant 0.36 isoniazid
ethionamide
inhA 1674471 c.270G>T synonymous_variant 0.55 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.6 isoniazid
ethionamide
inhA 1674489 c.288G>T synonymous_variant 0.6 isoniazid
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.63 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.6 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 0.59 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 0.59 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.61 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.56 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.56 isoniazid
ethionamide
inhA 1674601 p.Leu134Thr missense_variant 0.57 isoniazid
ethionamide
inhA 1674624 c.423A>T synonymous_variant 0.61 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 0.63 isoniazid
ethionamide
inhA 1674636 c.435C>G synonymous_variant 0.63 isoniazid
ethionamide
inhA 1674651 c.450C>T synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.71 isoniazid
ethionamide
inhA 1674714 c.513C>G synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674729 c.528G>T synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674738 c.537C>G synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674746 p.Tyr182Phe missense_variant 0.64 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674756 c.555T>A synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674771 c.570C>G synonymous_variant 0.63 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.63 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674786 c.585G>A synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674795 c.594G>C synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.63 isoniazid
ethionamide
inhA 1674804 c.603G>C synonymous_variant 0.62 isoniazid
ethionamide Not assoc w R - Interim
inhA 1674816 c.615T>G synonymous_variant 0.6 isoniazid
ethionamide
inhA 1674840 c.639C>G synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.64 isoniazid
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.57 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.52 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.52 isoniazid
ethionamide
inhA 1674934 c.733C>T synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674939 c.738G>C synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674957 c.756G>C synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674960 c.759C>G synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674966 c.765T>G synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674967 p.Asp256Thr missense_variant 0.44 isoniazid
ethionamide
inhA 1674993 c.792G>C synonymous_variant 0.41 isoniazid
ethionamide
inhA 1674994 p.His265Ser missense_variant 0.41 isoniazid
ethionamide
inhA 1675008 c.807C>G synonymous_variant 0.36 isoniazid
ethionamide
inhA 1675010 c.799delG frameshift_variant 0.36 isoniazid
ethionamide
rpsA 1833251 c.-291A>G upstream_gene_variant 0.24 pyrazinamide
rpsA 1833257 c.-285C>A upstream_gene_variant 0.25 pyrazinamide
rpsA 1833262 c.-280T>C upstream_gene_variant 0.23 pyrazinamide
rpsA 1833268 c.-274C>A upstream_gene_variant 0.24 pyrazinamide
rpsA 1833273 c.-269G>A upstream_gene_variant 0.24 pyrazinamide
rpsA 1833289 c.-253G>A upstream_gene_variant 0.23 pyrazinamide
rpsA 1833294 c.-248A>C upstream_gene_variant 0.23 pyrazinamide
rpsA 1833298 c.-244G>A upstream_gene_variant 0.23 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.26 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 0.35 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.45 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 0.54 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.51 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 0.54 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.54 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.55 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.55 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1833793 c.252C>T synonymous_variant 0.6 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.61 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 0.54 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.55 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.55 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.58 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.59 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.59 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.54 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.51 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.5 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.46 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.47 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 0.45 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.5 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.5 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.57 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1834222 c.681T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 0.59 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.59 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.62 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.67 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.66 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.61 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.59 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834540 c.999G>T synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
rpsA 1834546 c.1005T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.52 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.52 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.51 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.51 pyrazinamide
rpsA 1834669 c.1128G>C synonymous_variant 0.52 pyrazinamide
rpsA 1834684 c.1143C>G synonymous_variant 0.5 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.43 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.45 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.38 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.36 pyrazinamide
rpsA 1834775 p.Ala412Asn missense_variant 0.31 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.31 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.29 pyrazinamide
rpsA 1834792 c.1251G>T synonymous_variant 0.28 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.59 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.6 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.6 linezolid
tsnR 1853390 c.-216G>A upstream_gene_variant 0.59 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.59 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.59 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.58 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.56 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.48 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.47 linezolid
tsnR 1853459 c.-147G>T upstream_gene_variant 0.4 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.38 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.37 linezolid
tsnR 1853469 c.-137G>T upstream_gene_variant 0.37 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.34 linezolid
tsnR 1853484 c.-122_-121delAGinsGC upstream_gene_variant 0.34 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.34 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.35 linezolid
tsnR 1853498 c.-108G>C upstream_gene_variant 0.35 linezolid
tsnR 1853504 c.-102C>G upstream_gene_variant 0.35 linezolid
tsnR 1853513 c.-93C>G upstream_gene_variant 0.33 linezolid
tsnR 1853517 c.-89G>A upstream_gene_variant 0.27 linezolid
tsnR 1853522 c.-84C>G upstream_gene_variant 0.27 linezolid
tsnR 1853531 c.-75A>C upstream_gene_variant 0.24 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 0.98 capreomycin Not assoc w R
tlyA 1917996 c.57A>C synonymous_variant 0.24 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.27 capreomycin
tlyA 1918026 c.87C>G synonymous_variant 0.27 capreomycin
tlyA 1918029 c.90C>G synonymous_variant 0.27 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.27 capreomycin
tlyA 1918048 p.Leu37Met missense_variant 0.28 capreomycin
tlyA 1918057 p.Val40Arg missense_variant 0.25 capreomycin
tlyA 1918067 p.Ala43Gly missense_variant 0.25 capreomycin
tlyA 1918080 c.141C>A synonymous_variant 0.22 capreomycin
tlyA 1918082 p.Asp48Val missense_variant 0.22 capreomycin
tlyA 1918092 c.153G>C synonymous_variant 0.24 capreomycin
tlyA 1918113 c.174T>C synonymous_variant 0.25 capreomycin
tlyA 1918121 p.Ala61Gly missense_variant 0.24 capreomycin
tlyA 1918146 c.207A>G synonymous_variant 0.25 capreomycin
tlyA 1918149 c.210A>C synonymous_variant 0.26 capreomycin
tlyA 1918150 p.Val71Ile missense_variant 0.26 capreomycin
tlyA 1918155 c.216T>G synonymous_variant 0.26 capreomycin
tlyA 1918164 p.Glu75Asp missense_variant 0.25 capreomycin
tlyA 1918167 c.228G>C synonymous_variant 0.25 capreomycin
tlyA 1918182 c.243G>T synonymous_variant 0.26 capreomycin
tlyA 1918191 c.252G>C synonymous_variant 0.26 capreomycin
tlyA 1918197 c.258T>C synonymous_variant 0.23 capreomycin
tlyA 1918203 c.264C>T synonymous_variant 0.2 capreomycin
tlyA 1918477 p.Leu180Met missense_variant 0.19 capreomycin
bacA 2064912 c.-184A>G upstream_gene_variant 0.24 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064933 c.-205A>G upstream_gene_variant 0.31 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064945 c.-217G>A upstream_gene_variant 0.36 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.4 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 0.42 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.42 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064975 c.-247G>C upstream_gene_variant 0.42 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.41 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.41 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.42 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.43 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064996 c.-268G>C upstream_gene_variant 0.43 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101795 c.1248G>C synonymous_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2101804 c.1239T>G synonymous_variant 0.31 isoniazid
delamanid
ethionamide
ndh 2101808 p.Thr412Ser missense_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2101830 p.Ile405Val missense_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2101837 p.Ala402Val missense_variant 0.32 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101872 p.Ile391Phe missense_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101873 p.Phe390Leu missense_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101876 c.1167C>G synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101888 c.1155T>G synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2101891 c.1152C>G synonymous_variant 0.26 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2101912 c.1131G>C synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101915 c.1128T>C synonymous_variant 0.28 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101920 c.1123A>C synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101921 c.1122G>C synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>G synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101930 c.1113C>G synonymous_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2101936 c.1107G>C synonymous_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>C synonymous_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2101942 c.1101G>A synonymous_variant 0.28 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2101960 c.1083A>G synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101966 c.1077T>C synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101969 p.Glu358Asp missense_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101972 c.1071G>C synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101981 c.1062C>G synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2101988 p.Ala352Gly missense_variant 0.22 isoniazid
delamanid
ethionamide
ndh 2101990 c.1053G>C synonymous_variant 0.22 isoniazid
delamanid
ethionamide
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517917 c.-198G>T upstream_gene_variant 0.41 isoniazid
kasA 2517926 c.-189G>A upstream_gene_variant 0.39 isoniazid
kasA 2517950 c.-165C>T upstream_gene_variant 0.43 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.43 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.43 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.4 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.33 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.33 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.27 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.28 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.28 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.29 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.29 isoniazid
kasA 2518053 c.-62_-60delATTinsCTG upstream_gene_variant 0.29 isoniazid
kasA 2518059 c.-56_-54delTCGinsACC upstream_gene_variant 0.29 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 0.28 isoniazid
kasA 2518076 c.-39C>T upstream_gene_variant 1.0 isoniazid
kasA 2518079 c.-36T>C upstream_gene_variant 0.29 isoniazid
kasA 2518088 c.-27T>C upstream_gene_variant 0.28 isoniazid
kasA 2518089 c.-26C>A upstream_gene_variant 0.28 isoniazid
kasA 2518092 c.-23G>T upstream_gene_variant 0.28 isoniazid
kasA 2518100 c.-15T>G upstream_gene_variant 0.27 isoniazid
kasA 2518103 c.-12G>A upstream_gene_variant 0.26 isoniazid
kasA 2518106 c.-9C>G upstream_gene_variant 0.27 isoniazid
kasA 2518109 c.-6G>C upstream_gene_variant 0.27 isoniazid
kasA 2518110 c.-5_-4delTCinsAG upstream_gene_variant 0.27 isoniazid
kasA 2518120 c.6T>C synonymous_variant 0.27 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 0.27 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.28 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.3 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.3 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.32 isoniazid
kasA 2518168 c.54C>T synonymous_variant 0.3 isoniazid
kasA 2518172 p.Thr20Ala missense_variant 0.3 isoniazid
kasA 2518183 c.69G>A synonymous_variant 0.29 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.3 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.26 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.22 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.3 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.3 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.37 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.39 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.41 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.46 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.53 isoniazid
kasA 2518573 c.459G>A synonymous_variant 0.53 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.53 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.55 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.58 isoniazid
kasA 2518591 c.477G>T synonymous_variant 0.58 isoniazid
kasA 2518603 c.489G>C synonymous_variant 0.59 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.6 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.61 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.64 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.65 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.64 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.66 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.66 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.66 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.67 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.69 isoniazid
kasA 2518705 c.591T>G synonymous_variant 0.69 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.68 isoniazid
kasA 2518714 c.600A>T synonymous_variant 0.68 isoniazid
kasA 2518723 c.609G>A synonymous_variant 0.7 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.66 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.62 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.6 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.6 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.56 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.56 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.58 isoniazid
kasA 2518834 c.720C>T synonymous_variant 0.58 isoniazid
kasA 2518837 c.723G>A synonymous_variant 0.57 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.57 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.55 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.54 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.47 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.45 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.42 isoniazid
kasA 2518882 c.768C>T synonymous_variant 0.38 isoniazid
kasA 2518897 c.783G>A synonymous_variant 0.35 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.35 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.33 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.32 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.27 isoniazid
folC 2746416 p.Glu395Gln missense_variant 0.26 para-aminosalicylic_acid
folC 2746420 c.1179A>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746450 p.Gly383Ala missense_variant 0.36 para-aminosalicylic_acid
folC 2746453 c.1146G>C synonymous_variant 0.35 para-aminosalicylic_acid
folC 2746474 c.1125G>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746478 p.Phe374Tyr missense_variant 0.32 para-aminosalicylic_acid
folC 2746480 c.1119A>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746492 c.1107G>A synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746495 p.His368Asp missense_variant 0.3 para-aminosalicylic_acid
folC 2746498 c.1101G>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746504 c.1095G>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746507 p.Gln364Arg missense_variant 0.3 para-aminosalicylic_acid
folC 2746510 c.1089A>G synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746516 c.1083T>G synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746519 p.Ser360Ala missense_variant 0.3 para-aminosalicylic_acid
folC 2746525 c.1074G>T synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746531 c.1068G>C synonymous_variant 0.32 para-aminosalicylic_acid
folC 2746534 c.1065T>C synonymous_variant 0.32 para-aminosalicylic_acid
folC 2746540 c.1059G>C synonymous_variant 0.34 para-aminosalicylic_acid
folC 2746551 p.Ile350Leu missense_variant 0.32 para-aminosalicylic_acid
folC 2746564 c.1035A>C synonymous_variant 0.37 para-aminosalicylic_acid
folC 2746576 c.1023C>G synonymous_variant 0.36 para-aminosalicylic_acid
folC 2746584 c.1015T>C synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746594 c.1005T>C synonymous_variant 0.41 para-aminosalicylic_acid
folC 2746599 p.Thr334Ala missense_variant 0.42 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 0.41 para-aminosalicylic_acid
folC 2746618 c.981G>C synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746621 c.978C>G synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746627 p.Asp324Glu missense_variant 0.38 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 0.38 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 0.24 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 0.26 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.28 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747101 c.498G>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.3 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.32 para-aminosalicylic_acid
folC 2747158 c.441G>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747164 c.435T>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747167 p.Lys144Asn missense_variant 0.3 para-aminosalicylic_acid
folC 2747168 c.427_430delGGTA frameshift_variant 0.31 para-aminosalicylic_acid
folC 2747174 c.420_424delTTCTG frameshift_variant 0.31 para-aminosalicylic_acid
folC 2747191 p.Gln136Ala missense_variant 0.32 para-aminosalicylic_acid
folC 2747199 p.Ile134Val missense_variant 0.32 para-aminosalicylic_acid
folC 2747202 p.Leu133Met missense_variant 0.32 para-aminosalicylic_acid
folC 2747204 p.Ala132Gln missense_variant 0.32 para-aminosalicylic_acid
folC 2747209 p.Leu130Phe missense_variant 0.32 para-aminosalicylic_acid
folC 2747224 c.375G>C synonymous_variant 0.38 para-aminosalicylic_acid
folC 2747264 p.Gly112Ser missense_variant 0.43 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.42 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 0.39 para-aminosalicylic_acid
folC 2747287 p.Pro104Ala missense_variant 0.38 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.39 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 0.39 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.38 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.38 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.38 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.3 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.3 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 0.23 para-aminosalicylic_acid
Rv2477c 2782483 c.1560G>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782510 c.1533G>C synonymous_variant 0.34 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782581 c.1461_1462insAA frameshift_variant 0.42 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2782585 c.1457_1458insC frameshift_variant 0.43 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2782588 c.1452_1454delTCT disruptive_inframe_deletion 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782603 c.1440G>A synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782608 p.Gly479Ser missense_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782609 c.1434G>C synonymous_variant 0.43 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782612 c.1431T>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782624 c.1419G>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782636 c.1407G>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782651 c.1392T>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782669 c.1374A>G synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782680 c.1363T>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782684 c.1359T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782705 c.1338G>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782714 c.1329A>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782720 c.1323T>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782729 c.1314A>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782732 c.1311A>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782738 c.1305C>T synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782750 c.1293T>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782759 c.1284A>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782771 c.1272C>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782777 c.1266A>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782786 c.1257A>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782792 c.1251A>G synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782795 c.1248T>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782801 p.Gln414Val missense_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782807 p.Tyr412His missense_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782816 c.1227T>G synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782831 c.1212G>A synonymous_variant 0.35 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782837 c.1206C>G synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782841 p.Thr401Asn missense_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782849 c.1194G>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782861 c.1182T>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 0.33 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2782873 c.1170C>T synonymous_variant 0.34 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782876 c.1167G>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782879 c.1164C>T synonymous_variant 0.35 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782882 c.1161T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782885 c.1158G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782913 p.Ser377Ile missense_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.4 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782978 c.1065C>T synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.34 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.36 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.44 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783065 c.978C>T synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>G synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.53 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.62 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.61 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783193 p.Ser284Gly missense_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783203 c.840C>T synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783244 p.Thr267Ala missense_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783296 c.747C>T synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783356 c.687C>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Ala missense_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin
Rv2477c 2783432 c.610_611delAGinsTC synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783434 c.609C>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.49 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783551 c.492G>A synonymous_variant 0.53 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783554 c.489C>T synonymous_variant 0.53 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783629 c.414C>T synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.5 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783695 c.348C>T synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 c.285C>T synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783770 c.273G>A synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783812 c.231G>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783838 p.Thr69Ser missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783853 c.190C>T synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.55 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.5 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.48 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.38 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784016 c.27G>A synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
pepQ 2859690 c.729C>G synonymous_variant 0.3 bedaquiline
clofazimine
pepQ 2859702 c.715_717delTTGinsCTC synonymous_variant 0.31 bedaquiline
clofazimine
pepQ 2859723 c.696T>C synonymous_variant 0.36 bedaquiline
clofazimine Not assoc w R - Interim
pepQ 2859735 c.684G>C synonymous_variant 0.38 bedaquiline
clofazimine
pepQ 2859738 p.Ala227Gly missense_variant 0.38 bedaquiline
clofazimine
pepQ 2859747 c.672C>G synonymous_variant 0.39 bedaquiline
clofazimine
pepQ 2859750 c.669C>T synonymous_variant 0.42 bedaquiline
clofazimine
pepQ 2859765 c.654G>C synonymous_variant 0.44 bedaquiline
clofazimine
pepQ 2859777 c.639_641delGGT disruptive_inframe_deletion 0.42 bedaquiline
clofazimine
pepQ 2859782 c.636_637insGCC conservative_inframe_insertion 0.41 bedaquiline
clofazimine
pepQ 2859798 c.621G>T synonymous_variant 0.49 bedaquiline
clofazimine
pepQ 2859801 c.618G>C synonymous_variant 0.49 bedaquiline
clofazimine
pepQ 2859807 c.612C>T synonymous_variant 0.45 bedaquiline
clofazimine
pepQ 2859825 p.Ala198Pro missense_variant 0.43 bedaquiline
clofazimine
pepQ 2859831 c.588C>G synonymous_variant 0.44 bedaquiline
clofazimine
pepQ 2859834 c.585T>C synonymous_variant 0.44 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
pepQ 2859843 c.576G>C synonymous_variant 0.46 bedaquiline
clofazimine
pepQ 2859852 c.567A>G synonymous_variant 0.44 bedaquiline
clofazimine
pepQ 2859855 p.Val188Ile missense_variant 0.44 bedaquiline
clofazimine
pepQ 2859864 c.555T>C synonymous_variant 0.46 bedaquiline
clofazimine
pepQ 2859870 c.549T>C synonymous_variant 0.44 bedaquiline
clofazimine
pepQ 2859873 c.546T>C synonymous_variant 0.44 bedaquiline
clofazimine
pepQ 2859882 c.537G>C synonymous_variant 0.43 bedaquiline
clofazimine
pepQ 2859903 c.516G>C synonymous_variant 0.44 bedaquiline
clofazimine
pepQ 2859908 p.Gln171Glu missense_variant 0.44 bedaquiline
clofazimine
pepQ 2859909 c.510G>C synonymous_variant 0.44 bedaquiline
clofazimine
pepQ 2859918 c.501A>G synonymous_variant 0.42 bedaquiline
clofazimine
pepQ 2859921 c.498C>G synonymous_variant 0.42 bedaquiline
clofazimine
pepQ 2859939 c.480C>G synonymous_variant 0.34 bedaquiline
clofazimine
pepQ 2859942 c.477C>G synonymous_variant 0.33 bedaquiline
clofazimine
pepQ 2859950 c.469T>C synonymous_variant 0.31 bedaquiline
clofazimine
pepQ 2859957 c.462G>A synonymous_variant 0.31 bedaquiline
clofazimine
pepQ 2859963 c.456C>G synonymous_variant 0.24 bedaquiline
clofazimine
pepQ 2859966 c.453T>C synonymous_variant 0.24 bedaquiline
clofazimine
pepQ 2859972 c.447A>G synonymous_variant 0.25 bedaquiline
clofazimine
pepQ 2859981 c.438C>G synonymous_variant 0.23 bedaquiline
clofazimine
pepQ 2859984 c.435A>G synonymous_variant 0.24 bedaquiline
clofazimine
pepQ 2859987 c.432A>G synonymous_variant 0.24 bedaquiline
clofazimine
Rv2680 2996034 c.-71G>A upstream_gene_variant 0.24 capreomycin Uncertain significance
Rv2680 2996136 p.Ser11Asn missense_variant 0.24 capreomycin
Rv2752c 3064773 c.1419C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064776 c.1416T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064779 c.1413C>T synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064790 c.1402T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064815 c.1377T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064831 p.Ala454Asn missense_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064838 c.1354T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064872 c.1320T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3064877 p.Ser439Ala missense_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064881 c.1309_1311delAGTinsTCG synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064887 c.1305A>G synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064893 c.1299C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064896 c.1296T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064905 c.1287C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064911 c.1281C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064914 c.1278T>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064928 c.1264T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064932 c.1260T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064935 c.1257A>G synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064941 p.Gln417Glu missense_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064947 c.1245A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064956 p.Ser412Arg missense_variant 0.33 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3064962 c.1230C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064968 c.1224G>A synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064971 c.1221C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064974 c.1218T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064989 c.1203G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064995 c.1197C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064998 c.1194A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065013 c.1179G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065018 p.Asn392His missense_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065019 c.1173C>T synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065028 p.Val388Ile missense_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065430 c.762A>T synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065463 c.729T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065475 c.717C>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065481 c.711T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065490 c.702A>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065499 c.693A>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065511 c.681G>T synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065517 c.673_675delCTCinsTTG synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065520 c.672G>T synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065532 c.660A>G synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065553 c.639A>G synonymous_variant 0.43 levofloxacin
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065562 c.630T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065568 p.Ile208His missense_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065576 p.Ala206Ser missense_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065577 c.615C>T synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065580 c.612G>T synonymous_variant 0.44 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065583 c.609G>A synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065592 c.600G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065595 p.Leu199Phe missense_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065607 c.585C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065612 p.Thr194Ala missense_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065613 c.579C>T synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065625 c.567G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065634 c.558G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065637 c.555A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065640 c.552T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065649 c.543T>G synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065659 p.Pro178Leu missense_variant 0.27 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065661 c.531A>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065664 c.526_528delTTGinsCTT synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065667 c.525A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065675 p.Phe173Leu missense_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065697 c.495C>T synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065700 c.492C>G synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065703 c.489A>G synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065727 c.465C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065732 c.460T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065901 c.291A>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065916 c.276T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065946 p.Gly82Ala missense_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065979 c.213T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065985 c.207C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065988 c.204A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065997 c.195C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066002 p.Met64Leu missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066003 c.189C>T synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066045 c.147T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066087 c.105A>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3066095 p.Val33Ile missense_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066118 p.Asn25Ser missense_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066132 c.60G>T synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066135 c.57C>T synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066150 c.42C>A synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066153 p.Ser13Ala missense_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066158 p.Thr12Ala missense_variant 0.23 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3066161 c.31C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066165 c.27T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066176 p.Pro6Ala missense_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066177 c.15T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066350 c.-159T>A upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066357 c.-166G>T upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066370 c.-180_-179delAGinsGC upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066381 c.-190C>T upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066396 c.-207_-205delGCGinsACC upstream_gene_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066399 c.-210_-208delATTinsGCC upstream_gene_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066429 c.-238G>A upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066435 c.-246_-244delGGTinsAGC upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066441 c.-250C>G upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066452 c.-261T>A upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066453 c.-262G>A upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066456 c.-265A>G upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066459 c.-268T>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066465 c.-274G>A upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066471 c.-280A>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066476 c.-285C>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066480 c.-291_-289delGCCinsTCT upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066498 c.-307C>A upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066561 c.-370A>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066585 c.-394C>T upstream_gene_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066601 c.-410C>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066606 c.-415C>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066636 c.-447_-445delTCGinsGCC upstream_gene_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066639 c.-448G>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066657 c.-466C>G upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066660 c.-469C>T upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066665 c.-474G>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066672 c.-483_-481delGTGinsATA upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066676 c.-485C>T upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066681 c.-490G>T upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066696 c.-505T>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066707 c.-516A>G upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066734 c.-543G>A upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066741 c.-550T>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066747 c.-558_-556delCAAinsATC upstream_gene_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066758 c.-567C>A upstream_gene_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066798 c.-607G>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067269 p.Val226Ala missense_variant 0.24 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.27 para-aminosalicylic_acid
thyX 3067286 c.660C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067313 c.633G>C synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067319 c.627G>C synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067412 c.534C>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067463 p.Ile161Val missense_variant 0.5 para-aminosalicylic_acid
thyX 3067469 c.477C>T synonymous_variant 0.49 para-aminosalicylic_acid
thyX 3067472 c.474C>G synonymous_variant 0.49 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067496 c.450G>C synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067499 c.447G>A synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067502 c.444C>G synonymous_variant 0.49 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.5 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.5 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.48 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.46 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.44 para-aminosalicylic_acid
thyX 3067559 p.Arg129Gln missense_variant 0.44 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.43 para-aminosalicylic_acid
thyX 3067568 p.Ala126Pro missense_variant 0.43 para-aminosalicylic_acid
thyX 3067571 c.375C>T synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067586 c.360C>G synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.45 para-aminosalicylic_acid
thyX 3067616 c.330C>G synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067676 c.270C>G synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067679 p.Cys89Leu missense_variant 0.4 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067693 p.Ile85Val missense_variant 0.4 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067713 p.Val78Ala missense_variant 0.4 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.36 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.36 para-aminosalicylic_acid
thyX 3067774 p.Ala58Ser missense_variant 0.38 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067811 c.135G>A synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.28 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyA 3073836 c.636C>T synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3073845 c.627C>T synonymous_variant 0.25 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073872 p.Ile200Val missense_variant 0.29 para-aminosalicylic_acid
thyA 3073889 p.Ser195Ala missense_variant 0.29 para-aminosalicylic_acid
thyA 3073890 c.580_582delTTGinsCTC synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073893 p.Gly193Arg missense_variant 0.29 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.3 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.43 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.51 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.51 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.58 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074100 c.372T>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.56 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074121 c.351T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074124 c.348G>C synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074142 c.330C>T synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074147 p.Ile109Val missense_variant 0.53 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 0.52 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.48 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.48 para-aminosalicylic_acid
thyA 3074163 p.Ala103Thr missense_variant 0.48 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.49 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.49 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.43 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.39 para-aminosalicylic_acid
thyA 3074214 p.Asp86Ser missense_variant 0.3 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3074244 c.228A>C synonymous_variant 0.27 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
Rv3236c 3613405 c.-289G>C upstream_gene_variant 1.0 pyrazinamide
lpqB 3623393 c.1518A>C synonymous_variant 0.21 rifampicin
bedaquiline
lpqB 3623404 p.Ile503Leu missense_variant 0.24 rifampicin
bedaquiline
lpqB 3623408 c.1503C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623411 c.1500T>C synonymous_variant 0.24 rifampicin
bedaquiline
lpqB 3623417 c.1494A>C synonymous_variant 0.33 rifampicin
bedaquiline
lpqB 3623428 c.1483T>C synonymous_variant 0.33 rifampicin
bedaquiline
lpqB 3623441 p.Ser490Asn missense_variant 0.26 rifampicin
bedaquiline
lpqB 3623444 c.1467T>C synonymous_variant 0.26 rifampicin
bedaquiline
lpqB 3623465 c.1446G>C synonymous_variant 0.33 rifampicin
bedaquiline
lpqB 3623468 c.1443T>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623472 p.Tyr480Phe missense_variant 0.31 rifampicin
bedaquiline
lpqB 3623480 c.1431C>G synonymous_variant 0.32 rifampicin
bedaquiline
lpqB 3623484 p.Phe476Tyr missense_variant 0.36 rifampicin
bedaquiline
lpqB 3623492 c.1419T>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623507 c.1404C>G synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3623512 p.Gly467Ser missense_variant 0.39 rifampicin
bedaquiline
lpqB 3623516 c.1395C>G synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3623519 c.1392C>T synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3623528 c.1383G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623531 c.1380T>C synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3623552 c.1359G>C synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3623555 p.Gly452Ser missense_variant 0.4 rifampicin
bedaquiline
lpqB 3623561 c.1350T>C synonymous_variant 0.41 rifampicin
bedaquiline
lpqB 3623570 c.1341A>G synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3623573 c.1338T>G synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3623576 c.1335T>C synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3623580 p.Asn444Thr missense_variant 0.4 rifampicin
bedaquiline
lpqB 3623587 p.Ala442Pro missense_variant 0.41 rifampicin
bedaquiline
lpqB 3623597 c.1314C>G synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3623601 p.Ser437Thr missense_variant 0.38 rifampicin
bedaquiline
lpqB 3623612 p.Thr433Val missense_variant 0.38 rifampicin
bedaquiline
lpqB 3623629 p.Ile428Leu missense_variant 0.32 rifampicin
bedaquiline
lpqB 3623630 c.1281G>C synonymous_variant 0.32 rifampicin
bedaquiline
lpqB 3623648 c.1263A>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623654 p.Asp419Glu missense_variant 0.27 rifampicin
bedaquiline
lpqB 3623660 c.1251A>C synonymous_variant 0.29 rifampicin
bedaquiline
lpqB 3623663 c.1248G>C synonymous_variant 0.25 rifampicin
bedaquiline
lpqB 3623666 c.1245A>G synonymous_variant 0.26 rifampicin
bedaquiline
lpqB 3623671 c.1240C>T synonymous_variant 0.26 rifampicin
bedaquiline
lpqB 3623676 p.Val412Asn missense_variant 0.26 rifampicin
bedaquiline
lpqB 3623682 p.Thr410Gly missense_variant 0.24 rifampicin
bedaquiline
lpqB 3623684 c.1227T>C synonymous_variant 0.24 rifampicin
bedaquiline
lpqB 3623703 p.Ala403Val missense_variant 0.22 rifampicin
bedaquiline
lpqB 3624063 p.Asn283Ser missense_variant 0.35 rifampicin
bedaquiline
lpqB 3624074 c.837G>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3624077 c.834G>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3624082 c.829A>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3624089 c.822C>G synonymous_variant 0.37 rifampicin
bedaquiline
lpqB 3624094 c.817A>C synonymous_variant 0.37 rifampicin
bedaquiline
lpqB 3624100 c.811T>C synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624116 c.795A>G synonymous_variant 0.47 rifampicin
bedaquiline
lpqB 3624119 c.792C>G synonymous_variant 0.48 rifampicin
bedaquiline
lpqB 3624125 c.786A>G synonymous_variant 0.49 rifampicin
bedaquiline
lpqB 3624133 c.778A>C synonymous_variant 0.51 rifampicin
bedaquiline
lpqB 3624166 p.Met249Leu missense_variant 0.65 rifampicin
bedaquiline
lpqB 3624173 c.738A>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624179 c.732C>G synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624188 c.723G>C synonymous_variant 0.65 rifampicin
bedaquiline
lpqB 3624194 c.717C>G synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624200 c.711A>C synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624209 c.702A>C synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624224 c.687T>C synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624242 c.669A>G synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624245 c.666A>G synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624254 c.657T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624266 c.645T>C synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624269 c.642G>C synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624276 p.Arg212His missense_variant 0.58 rifampicin
bedaquiline
lpqB 3624287 c.624G>C synonymous_variant 0.53 rifampicin
bedaquiline
lpqB 3624290 c.621C>G synonymous_variant 0.52 rifampicin
bedaquiline
lpqB 3624293 c.618A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624295 c.615delT frameshift_variant 0.51 rifampicin Uncertain significance
bedaquiline
lpqB 3624303 c.607_608delCTinsATC frameshift_variant&missense_variant 0.52 rifampicin Uncertain significance
bedaquiline
lpqB 3624308 c.603A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624316 p.Val199Ile missense_variant 0.52 rifampicin
bedaquiline
lpqB 3624317 c.594C>G synonymous_variant 0.52 rifampicin
bedaquiline
lpqB 3624339 p.Arg191His missense_variant 0.54 rifampicin
bedaquiline
lpqB 3624346 p.Ser189Pro missense_variant 0.51 rifampicin
bedaquiline
lpqB 3624362 c.549G>C synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3624371 c.540T>C synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3624377 c.534C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 0.31 rifampicin
bedaquiline
lpqB 3624395 c.516C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624398 c.513C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3625069 c.-159T>G upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625072 c.-162G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3625089 p.Ala509Ser missense_variant 0.23 rifampicin
bedaquiline
mtrB 3625093 p.Glu507Asp missense_variant 0.24 rifampicin
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 0.3 rifampicin
bedaquiline
lpqB 3625135 c.-225A>C upstream_gene_variant 0.3 rifampicin
bedaquiline
lpqB 3625138 c.-228C>G upstream_gene_variant 0.3 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 0.31 rifampicin
bedaquiline
lpqB 3625156 c.-246G>C upstream_gene_variant 0.31 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 0.3 rifampicin
bedaquiline
lpqB 3625186 c.-276T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625189 c.-279A>T upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3625204 p.Ser470Ala missense_variant 0.29 rifampicin
bedaquiline
lpqB 3625207 c.-297C>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625243 c.-333T>G upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625246 c.-336G>A upstream_gene_variant 0.28 rifampicin
bedaquiline
lpqB 3625255 c.-345T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625258 c.-348G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625273 c.-363C>G upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 0.23 rifampicin
bedaquiline
lpqB 3625513 c.-603G>C upstream_gene_variant 0.24 rifampicin
bedaquiline
lpqB 3625518 c.-608T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625528 c.-618G>T upstream_gene_variant 0.22 rifampicin
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.23 rifampicin
bedaquiline
lpqB 3625573 c.-663G>A upstream_gene_variant 0.23 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3625592 p.Ser341Asn missense_variant 0.31 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.31 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.34 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.37 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 0.36 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.36 rifampicin
bedaquiline
lpqB 3625630 c.-720C>G upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3625636 c.978C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.4 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.46 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrB 3625705 c.909C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625714 c.-804C>T upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625732 c.882C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.52 rifampicin
bedaquiline
lpqB 3625741 c.-831G>A upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.54 rifampicin Uncertain significance
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625797 p.Val273Met missense_variant 0.52 rifampicin Uncertain significance
bedaquiline Uncertain significance
lpqB 3625798 c.-888G>C upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 0.49 rifampicin
bedaquiline
mtrB 3625876 c.738G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625888 c.726G>A synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625909 c.-999T>G upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrB 3625927 c.687T>C synonymous_variant 0.47 rifampicin
bedaquiline
mtrB 3625930 c.684C>G synonymous_variant 0.46 rifampicin
bedaquiline
mtrB 3625936 c.678C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625942 c.672C>G synonymous_variant 0.45 rifampicin
bedaquiline
mtrB 3625945 c.669A>G synonymous_variant 0.45 rifampicin
bedaquiline
mtrB 3625951 c.663A>G synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3625955 p.Leu220Ala missense_variant 0.42 rifampicin
bedaquiline
mtrB 3625967 p.Ala216Ile missense_variant 0.42 rifampicin
bedaquiline
mtrB 3625972 c.642G>C synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3625978 c.636T>C synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3625988 p.Thr209Gln missense_variant 0.39 rifampicin
bedaquiline
mtrB 3625993 c.621G>C synonymous_variant 0.39 rifampicin
bedaquiline
mtrB 3625999 c.615A>G synonymous_variant 0.41 rifampicin
bedaquiline
mtrB 3626006 p.Ser203Asn missense_variant 0.43 rifampicin
bedaquiline
mtrB 3626009 p.Ala202Lys missense_variant 0.42 rifampicin
bedaquiline
mtrB 3626017 c.597T>C synonymous_variant 0.45 rifampicin
bedaquiline
mtrB 3626029 c.585A>T synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3626048 p.Arg189Gln missense_variant 0.4 rifampicin
bedaquiline
mtrB 3626050 c.564G>T synonymous_variant 0.4 rifampicin
bedaquiline
mtrB 3626054 p.Leu187Ser missense_variant 0.39 rifampicin
bedaquiline
mtrB 3626058 p.Thr186Ala missense_variant 0.38 rifampicin
bedaquiline
mtrB 3626062 p.Thr184Ser missense_variant 0.39 rifampicin
bedaquiline
mtrB 3626070 p.Ile182Val missense_variant 0.39 rifampicin
bedaquiline
mtrB 3626077 c.537C>G synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626083 c.531G>A synonymous_variant 0.41 rifampicin
bedaquiline
mtrB 3626092 c.522T>G synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626095 p.Glu173Asp missense_variant 0.44 rifampicin
bedaquiline
mtrB 3626101 p.Gln171His missense_variant 0.44 rifampicin
bedaquiline
mtrB 3626107 c.507G>C synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3626124 p.Ala164Ser missense_variant 0.41 rifampicin
bedaquiline
mtrB 3626125 c.489C>G synonymous_variant 0.4 rifampicin
bedaquiline
mtrB 3626134 c.480C>G synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3626157 p.Ala153Ser missense_variant 0.44 rifampicin
bedaquiline
mtrB 3626158 p.Asn152Ser missense_variant 0.44 rifampicin
bedaquiline
mtrB 3626170 c.444T>C synonymous_variant 0.44 rifampicin
bedaquiline
mtrB 3626179 c.435A>G synonymous_variant 0.44 rifampicin
bedaquiline
mtrB 3626185 c.429T>C synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626188 p.Ser142Thr missense_variant 0.41 rifampicin
bedaquiline
mtrB 3626191 c.423C>G synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626194 c.420T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626203 c.411G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626206 c.408T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626209 c.405T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626236 c.378G>C synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3626239 c.375T>C synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626245 p.Leu123Met missense_variant 0.41 rifampicin
bedaquiline
mtrB 3626248 c.366C>G synonymous_variant 0.41 rifampicin
bedaquiline
mtrB 3626251 c.363T>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626254 c.360G>C synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3626260 c.354T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626263 c.351C>G synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626272 c.342A>G synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626275 c.339G>C synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626278 c.336G>C synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626284 c.330T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626293 c.321G>C synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626296 c.318T>G synonymous_variant 0.41 rifampicin
bedaquiline
mtrB 3626308 c.306T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626316 c.298C>T synonymous_variant 0.42 rifampicin
bedaquiline
mtrB 3626317 c.297A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626325 p.Thr97Ala missense_variant 0.43 rifampicin
bedaquiline
mtrB 3626329 c.285G>A synonymous_variant 0.44 rifampicin
bedaquiline
mtrB 3626332 c.282T>C synonymous_variant 0.45 rifampicin
bedaquiline
mtrB 3626349 p.Ser89Gly missense_variant 0.4 rifampicin
bedaquiline
mtrB 3626350 c.264C>G synonymous_variant 0.39 rifampicin
bedaquiline
mtrB 3626377 p.Asp79Glu missense_variant 0.27 rifampicin
bedaquiline
mtrB 3626383 c.231G>C synonymous_variant 0.26 rifampicin
bedaquiline
mtrB 3626386 c.228G>C synonymous_variant 0.24 rifampicin
bedaquiline
mtrB 3626390 p.Arg75Lys missense_variant 0.24 rifampicin
bedaquiline
mtrB 3626662 c.-49T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3626684 c.-71G>T upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrA 3626708 c.642G>A synonymous_variant 0.36 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3626720 c.-107G>A upstream_gene_variant 0.37 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.37 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrB 3626735 c.-122C>T upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrB 3626744 c.-131G>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626840 c.-227C>G upstream_gene_variant 0.57 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.57 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626849 c.-236C>T upstream_gene_variant 0.57 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.6 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.58 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.6 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3626891 c.-278G>C upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.63 rifampicin
bedaquiline
mtrB 3626912 c.-299T>G upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 0.63 rifampicin
bedaquiline
mtrA 3626939 c.411A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 0.63 rifampicin
bedaquiline
mtrB 3627005 c.-392G>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrB 3627023 c.-410C>G upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrA 3627056 c.294C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627065 c.-452G>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627074 c.-461G>C upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.6 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.6 rifampicin
bedaquiline
mtrA 3627269 c.81G>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627277 c.73C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627287 c.-676_-674delCTCinsTTG upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTC upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3627323 c.-712_-710delTTGinsCTC upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.43 rifampicin
bedaquiline
fbiB 3642587 p.Met351Ile missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiB 3642592 p.Val353Ala missense_variant 0.37 pretomanid
delamanid
clofazimine
fbiB 3642602 c.1068A>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiB 3642609 p.Ser359Ala missense_variant 0.31 pretomanid
delamanid
clofazimine
fbiB 3642614 c.1080C>T synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiB 3642620 c.1086T>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiB 3642656 c.1122G>C synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiB 3642662 c.1128C>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3642668 c.1134A>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3642674 c.1140C>A synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiB 3642677 c.1143A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiB 3642680 c.1146A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiB 3642684 c.1150T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiB 3642701 c.1167C>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiB 3642719 c.1185T>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
rpoA 3877515 c.993G>C synonymous_variant 0.21 rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.3 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.39 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.45 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.53 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.51 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.55 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.61 rifampicin
rpoA 3877770 c.738A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3877821 c.687C>G synonymous_variant 0.6 rifampicin
rpoA 3877839 c.669G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877842 c.666A>G synonymous_variant 0.6 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 0.61 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.63 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.63 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Asn missense_variant 0.6 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 0.6 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.62 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 0.63 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.61 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.61 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.62 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.62 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 0.61 rifampicin
rpoA 3878049 c.459G>C synonymous_variant 0.61 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.61 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.6 rifampicin
rpoA 3878064 c.444G>T synonymous_variant 0.6 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.6 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.61 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.64 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.61 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.62 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.62 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.62 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.62 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.62 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.61 rifampicin Uncertain significance
rpoA 3878163 c.345C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>G synonymous_variant 0.59 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.58 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.62 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.65 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.63 rifampicin
rpoA 3878307 c.201C>G synonymous_variant 0.63 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.64 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.59 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.59 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.59 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.59 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.57 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.59 rifampicin
rpoA 3878396 c.112C>T synonymous_variant 0.62 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.61 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.63 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.62 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.61 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 0.58 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.54 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.5 rifampicin
rpoA 3878483 c.25C>T synonymous_variant 0.43 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.43 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.43 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.46 rifampicin
rpoA 3878672 c.-165A>T upstream_gene_variant 0.62 rifampicin
rpoA 3878683 c.-176G>C upstream_gene_variant 0.6 rifampicin
rpoA 3878694 c.-187A>G upstream_gene_variant 0.58 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 0.6 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 0.62 rifampicin
rpoA 3878716 c.-209C>G upstream_gene_variant 0.66 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.68 rifampicin
rpoA 3878734 c.-229_-227delATCinsGTG upstream_gene_variant 0.61 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.63 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.63 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.63 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.65 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.69 rifampicin
rpoA 3878785 c.-278T>C upstream_gene_variant 0.71 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.71 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.69 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.69 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.62 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.57 rifampicin
rpoA 3878836 c.-331_-329delAAGinsGGC upstream_gene_variant 0.55 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.61 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 0.63 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.62 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.61 rifampicin Uncertain significance
rpoA 3878935 c.-428C>T upstream_gene_variant 0.6 rifampicin
rpoA 3878938 c.-431T>G upstream_gene_variant 0.59 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.59 rifampicin Uncertain significance
rpoA 3878956 c.-449G>C upstream_gene_variant 0.57 rifampicin
rpoA 3878962 c.-455G>C upstream_gene_variant 0.56 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.56 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGTG upstream_gene_variant 0.55 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.57 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.57 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 0.56 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.55 rifampicin
rpoA 3879028 c.-521C>T upstream_gene_variant 0.59 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 0.59 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.61 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.59 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.61 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.62 rifampicin
rpoA 3879097 c.-590C>T upstream_gene_variant 0.6 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.56 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.57 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.55 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.54 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.51 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.52 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.53 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.54 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.5 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.5 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.5 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.49 rifampicin
ddn 3986633 c.-211C>G upstream_gene_variant 0.41 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.4 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.35 pretomanid
delamanid
ddn 3986651 c.-193G>A upstream_gene_variant 0.34 pretomanid
delamanid
ddn 3986657 c.-187C>G upstream_gene_variant 0.34 pretomanid
delamanid
ddn 3986665 c.-179G>C upstream_gene_variant 0.32 pretomanid
delamanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.33 pretomanid
delamanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.24 pretomanid
delamanid
ddn 3986696 c.-148G>C upstream_gene_variant 0.23 pretomanid
delamanid
ddn 3986705 c.-139C>G upstream_gene_variant 0.22 pretomanid
delamanid
clpC1 4038212 c.2493T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038218 c.2487G>A synonymous_variant 0.26 pyrazinamide
clpC1 4038239 c.2466T>A synonymous_variant 0.33 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 0.33 pyrazinamide
clpC1 4038269 p.Pro812Ala missense_variant 0.37 pyrazinamide
clpC1 4038272 p.Gly811Ser missense_variant 0.36 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.37 pyrazinamide
clpC1 4038289 p.Asn806Asp missense_variant 0.38 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.4 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 0.42 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.43 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.47 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 0.47 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.48 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 0.53 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.54 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 0.59 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.57 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.53 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.5 pyrazinamide
clpC1 4038458 c.2247G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038486 p.Gly740Thr missense_variant 0.48 pyrazinamide
clpC1 4038488 c.2217C>G synonymous_variant 0.47 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.49 pyrazinamide
clpC1 4038498 p.Ser736Asn missense_variant 0.5 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.5 pyrazinamide
clpC1 4038533 p.Arg724Lys missense_variant 0.5 pyrazinamide
clpC1 4038587 c.2118C>T synonymous_variant 0.52 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.53 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.48 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.5 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.5 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.48 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.47 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.47 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.47 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.51 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.51 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.52 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.52 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.52 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.51 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.54 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.54 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.5 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.49 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.58 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.57 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.56 pyrazinamide
clpC1 4038938 c.1767C>T synonymous_variant 0.59 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.58 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.57 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.56 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.61 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.63 pyrazinamide
clpC1 4039025 c.1680C>G synonymous_variant 0.64 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.64 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.59 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.58 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.59 pyrazinamide
clpC1 4039121 c.1584T>G synonymous_variant 0.59 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.59 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.58 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.57 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.55 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.55 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.56 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.55 pyrazinamide
clpC1 4039199 c.1506C>G synonymous_variant 0.57 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.43 pyrazinamide
clpC1 4039328 p.Ala459Gly missense_variant 0.42 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.43 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4039364 c.1341C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.52 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.53 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.53 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.54 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.51 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039466 c.1239T>G synonymous_variant 0.48 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.48 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039514 c.1191C>T synonymous_variant 0.52 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.54 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.53 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4039616 c.1089G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.52 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.53 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.5 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.44 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.47 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.51 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.52 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.54 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.52 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.51 pyrazinamide
clpC1 4039868 c.837C>A synonymous_variant 0.51 pyrazinamide
clpC1 4039895 c.810G>A synonymous_variant 0.47 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.46 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.51 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.52 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.53 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.51 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 0.5 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 0.49 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.48 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.49 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 0.49 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.49 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.5 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.53 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
clpC1 4040171 c.534C>G synonymous_variant 0.58 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.56 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.55 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.58 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.61 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.61 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.64 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.67 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 0.7 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>A synonymous_variant 0.67 pyrazinamide
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.67 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
clpC1 4040330 c.375C>G synonymous_variant 0.66 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.65 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.65 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.61 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.59 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.57 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.5 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.43 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.42 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>A synonymous_variant 0.42 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.41 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.42 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>A synonymous_variant 0.42 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.42 pyrazinamide
clpC1 4040486 c.219G>C synonymous_variant 0.42 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>T synonymous_variant 0.38 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.38 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.38 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.38 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.39 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.41 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.41 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.39 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.39 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.39 pyrazinamide
clpC1 4040596 c.109C>T synonymous_variant 0.4 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.41 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.4 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.4 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.43 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.41 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.29 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040674 c.31A>C synonymous_variant 0.24 pyrazinamide
clpC1 4040675 c.30C>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040678 c.27C>A synonymous_variant 0.24 pyrazinamide
glpK 4138328 c.1428T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138333 p.Ser475Ala missense_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138337 p.Ala473Asp missense_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138340 c.1416G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138352 c.1404C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138360 c.1396T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138364 c.1392G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138370 c.1386C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138376 p.Val460Ala missense_variant 0.28 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
streptomycin Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138382 c.1374A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138385 c.1371A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138409 c.1347G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138418 c.1338T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138436 c.1320C>T synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138451 c.1305T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138463 c.1293C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138472 c.1284G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138478 c.1278T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138484 c.1272G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138490 c.1266G>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138493 p.Gln421Asp missense_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138496 c.1260G>T synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138502 c.1254T>G synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138511 c.1245C>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138514 c.1242A>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138517 p.Glu413Ala missense_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138535 c.1221T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138538 c.1218C>T synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138541 c.1215C>T synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138547 c.1209C>T synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138580 c.1176C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138601 c.1155G>T synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138607 c.1149G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138610 c.1146C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>A synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138643 c.1113A>C synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138654 c.1102C>T synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138661 c.1095T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138667 c.1089G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138670 c.1086G>T synonymous_variant 0.59 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138682 c.1074C>A synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138694 p.Pro354Asp missense_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138697 c.1059C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138706 c.1050C>A synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138714 p.Ala348Ser missense_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138715 c.1041G>A synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138721 c.1035G>A synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138769 c.987G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138774 p.Ser328Ala missense_variant 0.44 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138796 c.960A>G synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138817 c.939T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138822 p.Asn312Asp missense_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138829 c.927A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138832 c.924C>T synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139162 c.594C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139165 c.591A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139168 c.588T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139175 p.Val194Ala missense_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139177 c.579T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139183 c.573T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139186 c.570G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139189 c.567G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139198 c.558C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139204 c.552G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139207 c.549T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139228 p.Pro176Ala missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139231 c.525A>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139242 c.514T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139243 c.513A>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139249 c.507C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139255 c.501G>A synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139270 c.486C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139273 c.483A>G synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139276 c.480T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139282 c.474T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139285 p.Glu157Asp missense_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139297 c.459G>A synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139307 p.Gly150Ala missense_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139312 c.444T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139318 c.438T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139321 c.435T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139324 c.432A>C synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139330 c.426G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139339 c.417G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139348 c.408C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139356 p.Leu134Val missense_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139360 c.396A>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139363 c.393T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139366 c.390T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139372 c.384A>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139375 p.Asp127Glu missense_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139393 c.363C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139396 c.360C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
embC 4239298 c.-565C>T upstream_gene_variant 0.98 ethambutol Not assoc w R
embC 4240110 p.Asn83Thr missense_variant 0.22 ethambutol
embC 4240123 c.261C>G synonymous_variant 0.23 ethambutol
embC 4240127 p.Gln89Glu missense_variant 0.23 ethambutol
embC 4240150 c.288A>G synonymous_variant 0.24 ethambutol
embC 4240151 p.Ser97Pro missense_variant 0.23 ethambutol
embC 4240154 p.Gln98Gly missense_variant 0.23 ethambutol
embC 4240160 p.Thr100Ala missense_variant 0.25 ethambutol
embC 4240178 c.316T>C synonymous_variant 0.26 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.26 ethambutol
embC 4240204 c.342T>G synonymous_variant 0.23 ethambutol
embC 4240222 c.360G>A synonymous_variant 0.22 ethambutol
embC 4240229 p.Leu123Ile missense_variant 0.22 ethambutol
embC 4240233 p.Gln124Leu missense_variant 0.22 ethambutol
embC 4240244 p.Asp128Asn missense_variant 0.24 ethambutol
embC 4240258 c.396T>G synonymous_variant 0.27 ethambutol
embC 4240267 c.405T>C synonymous_variant 0.27 ethambutol
embC 4240270 c.408T>C synonymous_variant 0.28 ethambutol
embC 4240276 c.414G>C synonymous_variant 0.29 ethambutol
embC 4240277 p.Leu139Val missense_variant 0.29 ethambutol
embC 4240282 c.420C>G synonymous_variant 0.32 ethambutol
embC 4240288 c.426C>G synonymous_variant 0.33 ethambutol
embC 4240297 c.435T>C synonymous_variant 0.33 ethambutol
embC 4240307 p.Gly149Ser missense_variant 0.33 ethambutol Uncertain significance
embC 4240313 p.Thr151Ala missense_variant 0.32 ethambutol
embC 4240318 c.456T>C synonymous_variant 0.32 ethambutol
embC 4240325 c.463T>C synonymous_variant 0.31 ethambutol
embC 4240348 c.486T>C synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embC 4240355 p.Ala165Thr missense_variant 0.22 ethambutol Uncertain significance
embC 4240543 c.681G>C synonymous_variant 0.28 ethambutol
embC 4240558 c.696C>G synonymous_variant 0.26 ethambutol
embC 4240561 c.699C>G synonymous_variant 0.26 ethambutol
embC 4240574 p.Val238Leu missense_variant 0.28 ethambutol
embC 4240578 p.Ala239Val missense_variant 0.27 ethambutol
embC 4240582 c.720C>G synonymous_variant 0.27 ethambutol
embC 4240585 c.723C>G synonymous_variant 0.28 ethambutol
embC 4240587 p.Gly242Ala missense_variant 0.27 ethambutol
embC 4240598 p.Val246Ile missense_variant 0.27 ethambutol
embC 4240615 c.753G>C synonymous_variant 0.32 ethambutol
embC 4240630 c.768C>G synonymous_variant 0.35 ethambutol
embC 4240632 p.Met257Thr missense_variant 0.35 ethambutol
embC 4240642 c.780G>C synonymous_variant 0.4 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.38 ethambutol
embC 4240657 c.795G>C synonymous_variant 0.41 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.44 ethambutol Not assoc w R
embC 4240678 c.816T>G synonymous_variant 0.46 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.46 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.46 ethambutol
embC 4240698 p.Ala279Gly missense_variant 0.48 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.49 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.53 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.52 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.51 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.55 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.55 ethambutol
embC 4240859 p.Leu333Val missense_variant 0.59 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.6 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.58 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.57 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.55 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.53 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTTG synonymous_variant 0.53 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.5 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.51 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.5 ethambutol
embC 4240945 c.1083T>C synonymous_variant 0.52 ethambutol
embC 4240951 c.1089C>G synonymous_variant 0.49 ethambutol
embC 4240954 p.Ile364Met missense_variant 0.49 ethambutol
embC 4240957 c.1095C>G synonymous_variant 0.49 ethambutol
embC 4240966 c.1104G>C synonymous_variant 0.49 ethambutol
embC 4240978 c.1116G>A synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embC 4240979 p.Thr373Gln missense_variant 0.46 ethambutol
embC 4240983 p.Ser374Asn missense_variant 0.47 ethambutol
embC 4240990 c.1128A>C synonymous_variant 0.47 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.44 ethambutol
embC 4241020 c.1158G>C synonymous_variant 0.43 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.44 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.39 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.36 ethambutol
embC 4241048 c.1186_1188delCTTinsTTG synonymous_variant 0.36 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.35 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.38 ethambutol
embC 4241129 c.1267C>T synonymous_variant 0.36 ethambutol
embC 4241140 c.1278A>C synonymous_variant 0.37 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.39 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.36 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.36 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.32 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.35 ethambutol
embC 4241248 c.1386G>C synonymous_variant 0.31 ethambutol
embC 4241249 c.1387_1389delCGTinsAGA synonymous_variant 0.31 ethambutol
embC 4241256 p.Arg465Lys missense_variant 0.3 ethambutol
embC 4241259 p.Arg466Leu missense_variant 0.3 ethambutol
embC 4241266 c.1404C>T synonymous_variant 0.3 ethambutol
embC 4241268 p.Val469Ala missense_variant 0.29 ethambutol
embC 4241272 c.1410A>G synonymous_variant 0.29 ethambutol
embC 4241287 c.1425G>C synonymous_variant 0.29 ethambutol
embC 4241288 p.Ile476Leu missense_variant 0.29 ethambutol
embC 4241301 p.Ala480Val missense_variant 0.32 ethambutol Uncertain significance
embC 4241305 c.1443C>G synonymous_variant 0.3 ethambutol
embC 4241308 c.1446C>G synonymous_variant 0.3 ethambutol
embC 4241319 p.Pro486Leu missense_variant 0.32 ethambutol
embC 4241326 c.1464T>C synonymous_variant 0.28 ethambutol
embC 4241329 c.1467T>C synonymous_variant 0.28 ethambutol
embC 4241332 c.1470T>C synonymous_variant 0.28 ethambutol
embC 4241338 c.1476C>G synonymous_variant 0.29 ethambutol Not assoc w R - Interim
embC 4241339 p.Phe493Leu missense_variant 0.3 ethambutol
embC 4241344 c.1482G>C synonymous_variant 0.3 ethambutol
embC 4241361 p.Asn500Thr missense_variant 0.25 ethambutol
embC 4241363 p.Leu501Ala missense_variant 0.25 ethambutol
embC 4241374 c.1512T>C synonymous_variant 0.29 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.3 ethambutol
embC 4241392 c.1530G>C synonymous_variant 0.29 ethambutol
embC 4241394 p.Lys511Ser missense_variant 0.29 ethambutol
embC 4241407 c.1545A>G synonymous_variant 0.34 ethambutol
embC 4241411 p.Ile517Leu missense_variant 0.34 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.3 ethambutol
embC 4241452 c.1590G>C synonymous_variant 0.31 ethambutol
embC 4241453 p.Ile531Val missense_variant 0.31 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.28 ethambutol
embC 4241480 c.1618T>C synonymous_variant 0.28 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.29 ethambutol
embC 4241498 p.Val546Ile missense_variant 0.29 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.29 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.3 ethambutol
embC 4241515 c.1653G>C synonymous_variant 0.31 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.31 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embC 4241528 p.Arg556Lys missense_variant 0.31 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.32 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
embC 4241545 c.1683T>C synonymous_variant 0.33 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.34 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.36 ethambutol
embC 4241560 c.1698C>G synonymous_variant 0.41 ethambutol
embC 4241567 p.Ile569Ala missense_variant 0.39 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.45 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.46 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.46 ethambutol
embC 4241591 p.Leu577Val missense_variant 0.46 ethambutol
embC 4241608 c.1746C>G synonymous_variant 0.5 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.5 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.49 ethambutol
embC 4241617 c.1755G>A synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4241644 c.1782G>C synonymous_variant 0.47 ethambutol
embC 4241648 c.1786T>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embC 4241656 c.1794G>A synonymous_variant 0.4 ethambutol
embC 4241657 p.Ser599Pro missense_variant 0.4 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.42 ethambutol
embC 4241671 c.1809T>C synonymous_variant 0.41 ethambutol Not assoc w R - Interim
embC 4241689 c.1827G>C synonymous_variant 0.26 ethambutol
embC 4241694 p.Ala611Val missense_variant 0.22 ethambutol
embC 4241707 c.1845G>A synonymous_variant 0.22 ethambutol
embC 4241719 c.1857G>C synonymous_variant 0.24 ethambutol
embC 4241734 c.1872C>T synonymous_variant 0.24 ethambutol
embC 4242138 p.Leu759Gln missense_variant 0.2 ethambutol
embC 4242163 c.2301G>A synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embC 4242171 p.Thr770Asn missense_variant 0.23 ethambutol
embC 4242176 p.Pro772Ser missense_variant 0.23 ethambutol Uncertain significance
embC 4242179 p.Leu773Val missense_variant 0.23 ethambutol
embC 4242196 c.2334A>C synonymous_variant 0.23 ethambutol
embC 4242199 c.2337C>G synonymous_variant 0.23 ethambutol
embC 4242202 c.2340C>T synonymous_variant 0.23 ethambutol
embC 4242208 c.2346T>G synonymous_variant 0.23 ethambutol
embC 4242229 c.2367C>A synonymous_variant 0.21 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242803 p.Val981Leu missense_variant 1.0 ethambutol Not assoc w R
embA 4244178 p.Ala316Ser missense_variant 0.18 ethambutol
embA 4244189 c.957C>G synonymous_variant 0.25 ethambutol
embA 4244207 c.975C>G synonymous_variant 0.29 ethambutol
embA 4244219 c.987C>G synonymous_variant 0.3 ethambutol
embA 4244220 p.Leu330Val missense_variant 0.3 ethambutol
embA 4244227 p.Gly332Ala missense_variant 0.29 ethambutol
embA 4244247 p.Val339Ile missense_variant 0.38 ethambutol
embA 4244254 p.Arg341His missense_variant 0.38 ethambutol
embA 4244257 p.Phe342Trp missense_variant 0.38 ethambutol
embA 4244267 c.1035G>C synonymous_variant 0.44 ethambutol
embA 4244273 c.1041G>C synonymous_variant 0.45 ethambutol Not assoc w R - Interim
embA 4244282 c.1050C>G synonymous_variant 0.47 ethambutol
embA 4244284 p.Pro351Arg missense_variant 0.47 ethambutol
embA 4244291 c.1059G>C synonymous_variant 0.47 ethambutol
embA 4244298 p.Ser356Ala missense_variant 0.47 ethambutol
embA 4244306 c.1074G>A synonymous_variant 0.48 ethambutol
embA 4244309 c.1077C>G synonymous_variant 0.49 ethambutol
embA 4244312 c.1080T>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embA 4244315 c.1083G>C synonymous_variant 0.5 ethambutol
embA 4244324 c.1092T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embA 4244327 c.1095T>C synonymous_variant 0.5 ethambutol
embA 4244337 p.Leu369Val missense_variant 0.52 ethambutol
embA 4244340 p.Ser370Ala missense_variant 0.53 ethambutol
embA 4244345 c.1113C>G synonymous_variant 0.55 ethambutol
embA 4244366 c.1134C>A synonymous_variant 0.56 ethambutol
embA 4244372 c.1140T>G synonymous_variant 0.53 ethambutol
embA 4244378 c.1146G>A synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embA 4244390 c.1158G>C synonymous_variant 0.5 ethambutol
embA 4244393 c.1161G>C synonymous_variant 0.47 ethambutol
embA 4244396 c.1164T>C synonymous_variant 0.47 ethambutol
embA 4244408 c.1176G>C synonymous_variant 0.44 ethambutol
embA 4244412 p.Val394Met missense_variant 0.43 ethambutol
embA 4244415 c.1183T>C synonymous_variant 0.44 ethambutol
embA 4244426 c.1194G>C synonymous_variant 0.32 ethambutol
embA 4244427 p.Ser399Ala missense_variant 0.32 ethambutol
embA 4244438 c.1206C>G synonymous_variant 0.24 ethambutol
embA 4244439 p.Gly403Arg missense_variant 0.24 ethambutol Uncertain significance
embA 4244453 c.1221G>C synonymous_variant 0.26 ethambutol
embA 4244456 c.1224C>G synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embA 4244462 c.1230A>G synonymous_variant 0.25 ethambutol
embA 4244467 p.Ile412Thr missense_variant 0.25 ethambutol Uncertain significance
embA 4244479 p.Thr416Met missense_variant 0.21 ethambutol
embA 4244945 c.1713C>G synonymous_variant 0.36 ethambutol
embA 4244960 c.1728A>G synonymous_variant 0.4 ethambutol
embA 4244980 p.Val583Ala missense_variant 0.44 ethambutol
embA 4244982 c.1750T>C synonymous_variant 0.44 ethambutol
embA 4244987 c.1755T>C synonymous_variant 0.44 ethambutol
embA 4245003 p.Thr591Ala missense_variant 0.44 ethambutol Uncertain significance
embA 4245006 p.Phe592Leu missense_variant 0.42 ethambutol
embA 4245014 c.1782C>G synonymous_variant 0.41 ethambutol
embA 4245023 c.1791A>G synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embA 4245026 c.1794T>C synonymous_variant 0.4 ethambutol
embA 4245028 p.Ser599Asn missense_variant 0.41 ethambutol
embA 4245032 c.1800A>T synonymous_variant 0.42 ethambutol
embA 4245041 c.1809C>G synonymous_variant 0.45 ethambutol
embA 4245053 c.1821G>C synonymous_variant 0.41 ethambutol
embA 4245056 c.1824C>G synonymous_variant 0.42 ethambutol
embA 4245060 c.1828_1830delTTGinsCTC synonymous_variant 0.43 ethambutol
embA 4245078 p.Trp616Val missense_variant 0.41 ethambutol
embA 4245083 c.1851A>G synonymous_variant 0.41 ethambutol Not assoc w R - Interim
embA 4245093 p.Ile621Val missense_variant 0.43 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 0.43 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.42 ethambutol
embA 4245143 c.1911C>T synonymous_variant 0.41 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.39 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.36 ethambutol
embA 4245186 p.Thr652Ala missense_variant 0.33 ethambutol
embA 4245199 p.Leu656Pro missense_variant 0.23 ethambutol
embA 4245206 c.1974A>C synonymous_variant 0.24 ethambutol
embA 4245707 c.2475C>T synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embB 4245725 c.-789A>C upstream_gene_variant 0.23 ethambutol
embB 4245737 c.-777A>G upstream_gene_variant 0.28 ethambutol
embA 4245771 p.Asn847Tyr missense_variant 0.22 ethambutol
embA 4245785 c.2553G>C synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embB 4245788 c.-726C>G upstream_gene_variant 0.25 ethambutol
embB 4245797 c.-717C>G upstream_gene_variant 0.25 ethambutol
embA 4245818 c.2586C>T synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embA 4245834 p.Leu868Met missense_variant 0.21 ethambutol
embA 4245846 p.Ser872Thr missense_variant 0.21 ethambutol
embA 4246204 p.Arg991His missense_variant 0.24 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.25 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.25 ethambutol
embA 4246227 p.Ile999Val missense_variant 0.25 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embB 4246250 c.-264G>C upstream_gene_variant 0.24 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.24 ethambutol
embB 4246262 c.-252C>T upstream_gene_variant 0.24 ethambutol
embB 4246268 c.-246G>A upstream_gene_variant 0.23 ethambutol
embB 4246271 c.-243G>A upstream_gene_variant 0.23 ethambutol
embB 4246286 c.-228G>C upstream_gene_variant 0.26 ethambutol
embA 4246290 p.Leu1020Gly missense_variant 0.25 ethambutol
embA 4246299 p.Ser1023Ala missense_variant 0.27 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.28 ethambutol
embA 4246308 p.Thr1026Asp missense_variant 0.28 ethambutol
embB 4246313 c.-201C>G upstream_gene_variant 0.28 ethambutol
embB 4246319 c.-195G>T upstream_gene_variant 0.31 ethambutol
embA 4246331 c.3099C>T synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embA 4246338 p.Leu1036Met missense_variant 0.3 ethambutol
embB 4246361 c.-153C>G upstream_gene_variant 0.3 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.29 ethambutol
embA 4246383 p.Tyr1051His missense_variant 0.28 ethambutol
embB 4246400 c.-114G>C upstream_gene_variant 0.28 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.24 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.25 ethambutol
embB 4247437 c.924A>C synonymous_variant 0.3 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.33 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.36 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.4 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.39 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.37 ethambutol
embB 4247544 p.Ser344Thr missense_variant 0.38 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.38 ethambutol
embB 4247566 c.1053C>G synonymous_variant 0.35 ethambutol
embB 4247567 c.1054C>T synonymous_variant 0.35 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.34 ethambutol
embB 4247576 c.1063C>T synonymous_variant 0.34 ethambutol
embB 4247579 p.Ala356Ile missense_variant 0.35 ethambutol
embB 4247608 c.1095G>C synonymous_variant 0.36 ethambutol
embB 4247611 c.1098G>C synonymous_variant 0.36 ethambutol
embB 4247614 c.1101T>C synonymous_variant 0.37 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.34 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.34 ethambutol
embB 4247638 c.1125G>C synonymous_variant 0.31 ethambutol
embB 4247646 p.Glu378Ala missense_variant 0.26 ethambutol Not assoc w R
embB 4247684 c.1171T>C synonymous_variant 0.3 ethambutol
embB 4247687 c.1174C>T synonymous_variant 0.3 ethambutol
embB 4247692 c.1179C>G synonymous_variant 0.31 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.24 ethambutol
embB 4247729 p.Gly406Arg missense_variant 0.23 ethambutol
embB 4247741 p.Leu410Val missense_variant 0.24 ethambutol
embB 4247746 c.1233C>G synonymous_variant 0.24 ethambutol
embB 4247753 p.Val414Ile missense_variant 0.29 ethambutol Uncertain significance
embB 4247761 c.1248T>C synonymous_variant 0.35 ethambutol
embB 4247776 c.1263G>C synonymous_variant 0.43 ethambutol
embB 4247785 c.1272G>T synonymous_variant 0.44 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.47 ethambutol
embB 4247800 c.1287A>G synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embB 4247803 c.1290G>C synonymous_variant 0.48 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.47 ethambutol
embB 4247819 p.Val436Ile missense_variant 0.47 ethambutol Uncertain significance
embB 4247830 c.1317A>G synonymous_variant 0.42 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>C synonymous_variant 0.42 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>T synonymous_variant 0.43 ethambutol
embB 4247842 c.1329T>C synonymous_variant 0.45 ethambutol
embB 4247857 c.1344C>A synonymous_variant 0.45 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.46 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.45 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.48 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.46 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.44 ethambutol Not assoc w R - Interim
embB 4247908 c.1395C>T synonymous_variant 0.43 ethambutol
embB 4247909 c.1396T>C synonymous_variant 0.42 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embB 4247920 c.1407T>C synonymous_variant 0.43 ethambutol
embB 4247923 c.1410T>C synonymous_variant 0.44 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.43 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.41 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.42 ethambutol
embB 4247974 c.1461C>G synonymous_variant 0.4 ethambutol
embB 4247980 c.1467C>A synonymous_variant 0.41 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.35 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.35 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.35 ethambutol Uncertain significance
embB 4248044 p.Lys511Ser missense_variant 0.34 ethambutol
embB 4248052 c.1539G>C synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embB 4248055 c.1542G>C synonymous_variant 0.33 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.42 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.49 ethambutol
embB 4248088 c.1575C>T synonymous_variant 0.52 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.53 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.52 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.52 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.5 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.49 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.49 ethambutol
embB 4248149 p.Thr546Ala missense_variant 0.49 ethambutol Uncertain significance
embB 4248157 c.1644A>G synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embB 4248160 c.1647C>T synonymous_variant 0.49 ethambutol Not assoc w R - Interim
embB 4248169 c.1656C>G synonymous_variant 0.5 ethambutol
embB 4248172 c.1659G>C synonymous_variant 0.5 ethambutol
embB 4248175 c.1662G>C synonymous_variant 0.5 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.49 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.49 ethambutol Uncertain significance
embB 4248211 c.1698G>T synonymous_variant 0.49 ethambutol
embB 4248214 c.1701C>G synonymous_variant 0.49 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.49 ethambutol Not assoc w R - Interim
embB 4248226 c.1713G>C synonymous_variant 0.51 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.47 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.38 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.37 ethambutol
embB 4248322 c.1809G>A synonymous_variant 0.37 ethambutol Not assoc w R - Interim
embB 4248325 c.1812G>A synonymous_variant 0.38 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.27 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.25 ethambutol
embB 4248394 c.1881G>A synonymous_variant 0.26 ethambutol
embB 4248407 c.1894_1896delTTAinsCTG synonymous_variant 0.25 ethambutol
embB 4248410 p.Phe633Leu missense_variant 0.25 ethambutol
embB 4248416 p.Leu635Val missense_variant 0.25 ethambutol
embB 4249455 p.Thr981Lys missense_variant 0.24 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.31 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.35 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.35 ethambutol
embB 4249492 c.2979C>G synonymous_variant 0.35 ethambutol
embB 4249507 p.Gln998His missense_variant 0.37 ethambutol
embB 4249519 c.3006C>T synonymous_variant 0.33 ethambutol
embB 4249520 p.Ala1003Ser missense_variant 0.33 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.33 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.33 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.33 ethambutol
embB 4249544 p.Lys1011Glu missense_variant 0.34 ethambutol Uncertain significance
embB 4249558 c.3045A>C synonymous_variant 0.32 ethambutol
embB 4249568 p.Ser1019Asn missense_variant 0.35 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.35 ethambutol
embB 4249581 p.Leu1023Gln missense_variant 0.37 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.39 ethambutol
embB 4249598 p.Glu1029Gln missense_variant 0.39 ethambutol
embB 4249607 p.Thr1032Val missense_variant 0.44 ethambutol
embB 4249624 c.3111C>G synonymous_variant 0.47 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.45 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 0.23 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.24 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.24 ethambutol
ubiA 4269075 p.Ile253Val missense_variant 0.24 ethambutol
ubiA 4269091 p.Phe248Tyr missense_variant 0.24 ethambutol
aftB 4269102 c.-268_-266delAGCinsTCG upstream_gene_variant 0.24 ethambutol
ubiA 4269107 p.Tyr243His missense_variant 0.24 ethambutol
ubiA 4269109 p.Gly242His missense_variant 0.22 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 0.3 ethambutol
aftB 4269132 c.-296G>C upstream_gene_variant 0.38 ethambutol
ubiA 4269141 p.Leu231Ile missense_variant 0.35 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.36 ethambutol Not assoc w R - Interim
ubiA 4269164 p.Leu224Met missense_variant 0.38 ethambutol
aftB 4269177 c.-341G>C upstream_gene_variant 0.33 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.36 ethambutol
aftB 4269210 c.-374G>A upstream_gene_variant 0.31 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.3 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.31 ethambutol Not assoc w R - Interim
aftB 4269231 c.-395C>T upstream_gene_variant 0.28 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 0.28 ethambutol
ubiA 4269240 p.Leu198Val missense_variant 0.28 ethambutol Uncertain significance
ubiA 4269243 p.His197Gln missense_variant 0.28 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin