TB-Profiler result

Run: ERR4816466
Summary

Run ID: ERR4816466

Sample name:

Date: 2024-03-26T13:51:34.447157

Number of reads: 723242

Percentage reads mapped: 27.91

Median coverage: 19.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.07
La1.2.BCG M.bovis None 0.16
lineage4 Euro-American None 0.93
lineage1.2.1 Indo-Oceanic RD239 0.13
lineage4.9 Euro-American (H37Rv-like) None 0.8
La1.7.1 M.bovis None 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.235_237delGTCinsCG Assoc w R - Interim
c.217_219delGTGinsAC Assoc w R - Interim
c.160_162delTTGinsCC Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.409_411delGGGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.430_432delAGCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.709_711delCCCinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.727_729delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.766_768delGCTinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1120_1122delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1162_1164delATGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1825_1827delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1945_1947delATTinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1963_1965delGGCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2059_2061delACGinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.325_327delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.358_360delCAGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.235_237delGTCinsCG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.217_219delGTGinsAC Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.160_162delTTGinsCC Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491191 c.409_411delGGGinsCC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491212 c.430_432delAGCinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491491 c.709_711delCCCinsAG frameshift_variant&missense_variant 0.5 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491509 c.727_729delTTGinsCC frameshift_variant&missense_variant 0.45 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491548 c.766_768delGCTinsCC frameshift_variant&missense_variant 0.48 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsAG frameshift_variant&missense_variant 0.52 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304050 c.1120_1122delTTGinsCC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304092 c.1162_1164delATGinsCC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304755 c.1825_1827delCTAinsTG frameshift_variant&stop_gained 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304875 c.1945_1947delATTinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304893 c.1963_1965delGGCinsAT frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304989 c.2059_2061delACGinsGT frameshift_variant&missense_variant 0.61 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
katG 2155107 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.77 isoniazid Assoc w R High-level resistance
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
pepQ 2860182 c.235_237delGTCinsCG frameshift_variant&missense_variant 0.91 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
pepQ 2860200 c.217_219delGTGinsAC frameshift_variant&missense_variant 1.0 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
pepQ 2860257 c.160_162delTTGinsCC frameshift_variant&missense_variant 0.92 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
fbiA 3640867 c.325_327delCTGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3640900 c.358_360delCAGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 1.0 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.85 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 24 c.24C>T synonymous_variant 1.0 isoniazid
dnaA 51 c.51C>A synonymous_variant 1.0 isoniazid
dnaA 552 c.552G>C synonymous_variant 1.0 isoniazid
dnaA 555 c.555C>T synonymous_variant 0.91 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 594 c.594C>G synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.7 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.42 isoniazid
dnaA 633 c.633T>A synonymous_variant 1.0 isoniazid
dnaA 634 c.634_636delCTCinsTG frameshift_variant&missense_variant 0.4 isoniazid Uncertain significance
dnaA 639 c.639C>A synonymous_variant 0.58 isoniazid Not assoc w R - Interim
dnaA 645 c.645A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 649 c.649C>T synonymous_variant 0.44 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 660 c.660G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 1.0 isoniazid
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 690 c.690G>C synonymous_variant 0.54 isoniazid
dnaA 693 c.693A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.7 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.92 isoniazid
dnaA 771 c.771A>C synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.97 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.97 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.96 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 888 c.888C>G synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>G synonymous_variant 1.0 isoniazid
dnaA 912 c.912T>G synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 945 c.945G>A synonymous_variant 1.0 isoniazid
dnaA 951 c.951G>C synonymous_variant 1.0 isoniazid
dnaA 960 c.960C>G synonymous_variant 1.0 isoniazid
dnaA 963 c.963C>G synonymous_variant 1.0 isoniazid
dnaA 966 c.966T>C synonymous_variant 1.0 isoniazid
dnaA 969 c.969G>A synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>C synonymous_variant 1.0 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>G synonymous_variant 1.0 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 1.0 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 1.0 isoniazid
dnaA 1011 c.1011C>G synonymous_variant 1.0 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 1.0 isoniazid
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 1.0 isoniazid
dnaA 1071 c.1071C>A synonymous_variant 1.0 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.96 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 1.0 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 0.85 isoniazid
dnaA 1134 c.1134G>C synonymous_variant 0.78 isoniazid
dnaA 1140 c.1140C>G synonymous_variant 1.0 isoniazid
dnaA 1149 c.1149C>A synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.8 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 0.75 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 0.76 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.72 isoniazid
dnaA 1218 c.1218C>G synonymous_variant 0.72 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1224 c.1224C>G synonymous_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.71 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>T synonymous_variant 1.0 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.8 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1326 c.1326G>A synonymous_variant 0.74 isoniazid Not assoc w R - Interim
dnaA 1332 c.1332A>G synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1341 c.1341G>A synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 1347 c.1347C>T synonymous_variant 1.0 isoniazid
dnaA 1348 c.1348C>T synonymous_variant 0.64 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.66 isoniazid Not assoc w R - Interim
dnaA 1368 c.1368T>C synonymous_variant 1.0 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 1.0 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1395 c.1395G>T synonymous_variant 0.39 isoniazid
dnaA 1401 c.1401C>T synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.41 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 1.0 isoniazid
dnaA 1419 c.1419C>G synonymous_variant 1.0 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.39 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.39 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1461 c.1461C>A synonymous_variant 1.0 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.45 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 1.0 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1476 c.1476T>C synonymous_variant 0.45 isoniazid
dnaA 1485 c.1485A>G synonymous_variant 0.53 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 1.0 isoniazid
gyrB 6142 c.903G>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6169 c.930C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrB 6208 c.969G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6214 c.975G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6217 c.978G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6316 c.-986G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6370 c.1131C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6379 c.-923C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6396 p.Lys386Arg missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>A upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6413 c.-889C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6592 c.-710C>T upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6658 c.-644G>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6721 c.1482C>T synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6766 c.-536G>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6862 c.-440C>A upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6865 c.-437G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>A upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>A upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrB 6937 c.1698G>A synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6950 c.1711_1713delCTCinsTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7051 c.1812A>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7159 c.1920C>T synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7162 c.1923C>T synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7192 c.-110G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7424 c.123G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7430 c.129G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7511 c.210C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7556 c.255C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7574 c.273G>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7625 c.324G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7628 c.327G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7703 c.402G>A synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7874 c.573G>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8185 p.Lys295Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8216 c.915G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8231 c.930C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8261 c.960C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8270 c.969G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8279 c.978G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8309 c.1008G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8384 c.1083G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8426 c.1125G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>A synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8498 c.1197C>T synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8597 c.1296C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>T synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8628 c.1327C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8639 c.1338G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8735 c.1434C>T synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8741 c.1440C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8747 c.1446A>G synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8954 c.1653G>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8978 c.1677C>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8982 p.Cys561Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9002 c.1701C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9077 c.1776C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>A synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9212 c.1911G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9272 c.1971C>T synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 c.1999_2001delGCCinsTG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9317 c.2016G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9552 c.2251C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9572 c.2271C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9575 c.2274G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9583 p.Arg761Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9597 c.2296T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9647 c.2346C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9665 c.2364A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9686 c.2385A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
Rv0010c 13834 c.-276A>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13843 c.-285T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13852 c.-296_-294delTTAinsCG upstream_gene_variant 1.0 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13861 c.-303C>T upstream_gene_variant 1.0 isoniazid
Rv0010c 13867 c.-309C>T upstream_gene_variant 0.86 isoniazid
Rv0010c 13879 c.-321T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13891 c.-335_-333delTCGinsGT upstream_gene_variant 0.83 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.83 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 1.0 isoniazid
fgd1 490815 c.33G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490836 c.54C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490866 c.84A>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490968 c.186C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491038 p.Ile86Val missense_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491070 c.288G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491100 c.318C>T synonymous_variant 0.38 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491109 c.327G>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491154 c.372G>A synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491169 c.387C>T synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491243 p.Tyr154Phe missense_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.7 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>A synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491322 c.540G>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491328 c.546C>A synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 c.720G>A synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491583 c.801G>A synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574640 c.-708G>T upstream_gene_variant 0.55 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574692 c.-656_-654delCTCinsTG upstream_gene_variant 0.8 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574727 c.-621G>C upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574742 c.-606G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575587 c.240C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.86 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575650 c.303G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575653 c.306G>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575659 c.312A>C synonymous_variant 0.84 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575674 c.327G>A synonymous_variant 0.69 ethionamide
isoniazid
mshA 575678 p.Asn111His missense_variant 0.35 ethionamide
isoniazid
mshA 575686 c.339G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 0.63 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.62 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.38 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.62 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.6 ethionamide
isoniazid
mshA 575739 p.Ala131Gly missense_variant 0.4 ethionamide
isoniazid
mshA 575751 p.Gly135Ala missense_variant 0.45 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 0.43 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.42 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.58 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575816 c.469C>T synonymous_variant 0.63 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575833 c.486C>T synonymous_variant 0.66 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575837 c.490_492delCTGinsTC frameshift_variant&missense_variant 0.35 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575842 c.495G>C synonymous_variant 0.66 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 0.82 ethionamide
isoniazid Not assoc w R - Interim
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 0.88 ethionamide
isoniazid
mshA 575924 p.Gly193Ser missense_variant 0.88 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619516 c.-375C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>G upstream_gene_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 619560 c.-331_-330delCGinsGC upstream_gene_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 619573 c.-318G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619618 c.-273C>G upstream_gene_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 619621 c.-270C>T upstream_gene_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-256delTCinsCT upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620169 c.279G>C synonymous_variant 0.39 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620203 p.Val105Pro missense_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620235 c.345C>T synonymous_variant 0.4 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>T synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 c.367_369delATCinsCG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620265 c.375C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620268 c.378G>C synonymous_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Phe missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620275 c.385_387delCTGinsTA frameshift_variant&stop_gained 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.66 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>G synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>T synonymous_variant 0.43 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620424 c.534G>C synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620436 c.546T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620442 c.552G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620700 c.810C>T synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAG frameshift_variant&missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620809 c.919C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620823 c.933C>T synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656289 c.1182C>G synonymous_variant 0.9 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 1.0 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.67 ethionamide
Rv0565c 656307 c.1164G>C synonymous_variant 1.0 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.62 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656375 p.Asp366Asn missense_variant 1.0 ethionamide
Rv0565c 656383 p.Val363Thr missense_variant 1.0 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 1.0 ethionamide
Rv0565c 656403 c.1066_1068delGCCinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656412 c.1057_1059delCTTinsTG frameshift_variant&synonymous_variant 0.94 ethionamide Uncertain significance
Rv0565c 656418 c.1053A>G synonymous_variant 1.0 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 1.0 ethionamide
Rv0565c 656424 c.1047G>A synonymous_variant 0.88 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>G synonymous_variant 1.0 ethionamide
Rv0565c 656477 p.Lys332Gln missense_variant 1.0 ethionamide
Rv0565c 656478 c.993C>G synonymous_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 0.79 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>G synonymous_variant 1.0 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656529 c.942C>G synonymous_variant 0.72 ethionamide
Rv0565c 656535 c.936C>A synonymous_variant 1.0 ethionamide
Rv0565c 656539 p.Ser311Ala missense_variant 1.0 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 0.69 ethionamide
Rv0565c 656556 c.915G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656559 c.912C>T synonymous_variant 0.75 ethionamide
Rv0565c 656571 c.900C>T synonymous_variant 0.79 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 1.0 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 1.0 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 1.0 ethionamide
Rv0565c 656871 c.598_600delACCinsTG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656880 c.591C>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656885 p.Ile196Leu missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656889 c.582A>C synonymous_variant 1.0 ethionamide
Rv0565c 656895 c.576G>C synonymous_variant 1.0 ethionamide
Rv0565c 656901 c.570C>G synonymous_variant 0.88 ethionamide
Rv0565c 656904 c.567G>T synonymous_variant 1.0 ethionamide
Rv0565c 656943 c.528G>C synonymous_variant 0.65 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 1.0 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 0.63 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 1.0 ethionamide
Rv0565c 656973 c.498A>G synonymous_variant 1.0 ethionamide
Rv0565c 656976 p.Ala165Ile missense_variant 1.0 ethionamide
Rv0565c 656979 c.492C>G synonymous_variant 0.48 ethionamide
Rv0565c 656983 p.Gly163Thr missense_variant 0.48 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656991 c.480G>A synonymous_variant 0.48 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657012 c.459C>T synonymous_variant 0.48 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.73 ethionamide
Rv0565c 657309 c.162C>T synonymous_variant 0.73 ethionamide
Rv0565c 657683 c.-213C>A upstream_gene_variant 0.62 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 728309 c.-3620_*5899del transcript_ablation 1.0 isoniazid Uncertain significance
hadA 731687 c.-243_-237delGCAAGACinsACGCACTTTTGAGAG upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 1.0 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 1.0 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731717 c.-213T>G upstream_gene_variant 0.34 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 1.0 isoniazid
hadA 731759 c.-171G>A upstream_gene_variant 0.44 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.35 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.69 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732238 c.309G>C synonymous_variant 1.0 isoniazid
hadA 732253 c.324T>C synonymous_variant 1.0 isoniazid
hadA 732259 c.330T>C synonymous_variant 1.0 isoniazid
hadA 732270 p.Glu114Val missense_variant 1.0 isoniazid
hadA 732272 c.343_345delGCGinsTT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732298 c.369C>G synonymous_variant 1.0 isoniazid
hadA 732304 c.375C>T synonymous_variant 0.82 isoniazid
hadA 732305 p.Ile126Val missense_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732319 c.390G>A synonymous_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732358 c.429G>C synonymous_variant 0.71 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.71 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732385 c.456A>G synonymous_variant 0.61 isoniazid
hadA 732389 p.Ser154Lys missense_variant 0.6 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.97 isoniazid
nusG 734129 c.-125G>C upstream_gene_variant 1.0 rifampicin
nusG 734144 c.-110G>T upstream_gene_variant 0.58 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 0.57 rifampicin
nusG 734177 c.-77_-76insCTG upstream_gene_variant 1.0 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734192 c.-62G>C upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 1.0 rifampicin
nusG 734222 c.-31_-27delGGCTC upstream_gene_variant 1.0 rifampicin
nusG 734229 c.-25A>C upstream_gene_variant 0.44 rifampicin
nusG 734230 c.-24G>A upstream_gene_variant 1.0 rifampicin
nusG 734236 c.-18delCinsTT upstream_gene_variant 1.0 rifampicin
nusG 734247 c.-7G>C upstream_gene_variant 1.0 rifampicin
nusG 734249 c.-5A>C upstream_gene_variant 0.56 rifampicin
nusG 734250 c.-4A>T upstream_gene_variant 0.44 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734457 c.204C>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734604 c.351C>T synonymous_variant 0.67 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.71 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.75 rifampicin
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
rpoB 760055 c.249G>C synonymous_variant 0.41 rifampicin
rpoB 760059 p.Tyr85Asp missense_variant 0.54 rifampicin
rpoB 760070 c.264T>C synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.4 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760313 c.507G>C synonymous_variant 1.0 rifampicin
rpoB 760323 c.517C>T synonymous_variant 0.64 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.61 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.55 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760388 c.582C>T synonymous_variant 0.53 rifampicin
rpoB 760389 c.583_584delAGinsTC synonymous_variant 0.53 rifampicin
rpoB 760400 c.594G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760403 c.597C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.42 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.59 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 0.43 rifampicin
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Ser missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760589 c.783C>G synonymous_variant 0.69 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.85 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760757 c.951T>C synonymous_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 1.0 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760916 c.1110C>G synonymous_variant 0.7 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.69 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760938 c.1132C>T synonymous_variant 0.71 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761129 c.1323G>A synonymous_variant 0.32 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 0.62 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.65 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 1.0 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761373 p.Val523His missense_variant 0.94 rifampicin
rpoB 761390 c.1584C>T synonymous_variant 0.32 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761426 c.1620G>A synonymous_variant 0.33 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761437 p.Ala544Gly missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 1.0 rifampicin
rpoB 761471 c.1665C>T synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.36 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>G synonymous_variant 0.65 rifampicin
rpoB 761552 c.1746G>C synonymous_variant 0.61 rifampicin
rpoB 761561 c.1755C>G synonymous_variant 0.65 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 0.39 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.53 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.47 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 1.0 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 1.0 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761747 c.1941G>T synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.46 rifampicin
rpoB 761867 c.2061C>T synonymous_variant 0.41 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 0.39 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761882 c.2076C>T synonymous_variant 0.4 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761903 c.2097T>G synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.48 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 0.4 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 0.55 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762004 p.Asn733Ser missense_variant 0.6 rifampicin Uncertain significance
rpoB 762008 c.2202C>G synonymous_variant 0.4 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762077 c.2271G>A synonymous_variant 0.56 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 0.99 rifampicin
rpoB 762146 c.2340G>A synonymous_variant 0.44 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 0.59 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.34 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.35 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762323 c.2517C>A synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.47 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.47 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.55 rifampicin
rpoB 762441 c.2635C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 762449 c.-921C>T upstream_gene_variant 0.51 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.56 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.97 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.97 rifampicin Uncertain significance
rpoC 762521 c.-849C>A upstream_gene_variant 0.96 rifampicin
rpoC 762524 c.-846G>C upstream_gene_variant 0.56 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoB 762722 c.2916C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762729 p.Gln975Lys missense_variant 1.0 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 1.0 rifampicin
rpoB 762750 p.Leu982Met missense_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 762795 p.Asp997Asn missense_variant 0.32 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>G upstream_gene_variant 1.0 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763079 c.-291C>T upstream_gene_variant 0.65 rifampicin
rpoB 763082 c.3276C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763200 c.3394_3396delCTAinsTG frameshift_variant&stop_gained 0.73 rifampicin
rpoC 763211 c.-159C>T upstream_gene_variant 0.71 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 0.7 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763250 c.-120C>T upstream_gene_variant 0.71 rifampicin
rpoC 763253 c.-117G>T upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>G upstream_gene_variant 1.0 rifampicin
rpoC 763402 c.33C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763450 c.81G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763459 c.90G>A synonymous_variant 0.62 rifampicin
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763537 c.168C>A synonymous_variant 0.67 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763624 c.255C>T synonymous_variant 0.32 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 0.64 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.65 rifampicin
rpoC 763702 c.333C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.65 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.65 rifampicin
rpoC 763723 c.354G>T synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763774 c.405G>C synonymous_variant 0.37 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.36 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.65 rifampicin
rpoC 763816 c.447C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>C synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763903 c.534G>A synonymous_variant 0.68 rifampicin
rpoC 763912 c.543G>C synonymous_variant 1.0 rifampicin
rpoC 763915 c.546C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763930 c.561G>A synonymous_variant 0.33 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763963 c.594C>G synonymous_variant 0.65 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.32 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.46 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764198 c.829C>T synonymous_variant 0.48 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764209 c.840C>G synonymous_variant 1.0 rifampicin
rpoC 764212 c.843C>T synonymous_variant 0.45 rifampicin
rpoC 764215 c.846A>G synonymous_variant 0.52 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.58 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.39 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.62 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.38 rifampicin
rpoC 764293 c.924G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.66 rifampicin
rpoC 764335 c.966G>A synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764359 c.990C>G synonymous_variant 0.69 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>A synonymous_variant 1.0 rifampicin
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 1.0 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.69 rifampicin
rpoC 764560 c.1191T>G synonymous_variant 0.65 rifampicin
rpoC 764563 c.1194G>A synonymous_variant 0.37 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.36 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.38 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>A synonymous_variant 0.36 rifampicin
rpoC 764713 c.1344G>A synonymous_variant 0.41 rifampicin
rpoC 764731 c.1362G>C synonymous_variant 0.57 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.44 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>G synonymous_variant 0.53 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.44 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.54 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.52 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.56 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.57 rifampicin
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>A synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>A synonymous_variant 0.85 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>G synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765298 c.1929G>C synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765379 c.2010G>C synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765403 c.2034G>A synonymous_variant 0.43 rifampicin
rpoC 765409 c.2040T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765412 c.2043T>C synonymous_variant 0.42 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765565 c.2196G>C synonymous_variant 0.6 rifampicin
rpoC 765571 c.2202C>T synonymous_variant 0.58 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.59 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 1.0 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 1.0 rifampicin
rpoC 765734 c.2365_2367delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.45 rifampicin
rpoC 765961 c.2592G>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>G synonymous_variant 0.38 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.6 rifampicin
rpoC 766021 c.2652G>T synonymous_variant 0.4 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766043 c.2674_2676delCAGinsGA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766054 c.2685C>T synonymous_variant 0.62 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.35 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766147 c.2778C>T synonymous_variant 1.0 rifampicin
rpoC 766178 p.Ile937Val missense_variant 1.0 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 1.0 rifampicin
rpoC 766192 c.2823T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 1.0 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 1.0 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766219 p.Asp950Glu missense_variant 1.0 rifampicin
rpoC 766222 c.2853T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766226 c.2857_2859delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766234 c.2865T>G synonymous_variant 1.0 rifampicin
rpoC 766237 c.2868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766240 c.2871T>C synonymous_variant 1.0 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 1.0 rifampicin
rpoC 766249 c.2880C>G synonymous_variant 0.88 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 1.0 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.56 rifampicin
rpoC 766291 c.2922G>C synonymous_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>T synonymous_variant 0.74 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>T synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766501 c.3132G>C synonymous_variant 0.69 rifampicin
rpoC 766522 c.3153C>A synonymous_variant 0.33 rifampicin
rpoC 766526 c.3157_3159delGTTinsAC frameshift_variant&missense_variant 0.66 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.31 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.64 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 1.0 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.35 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.63 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 0.62 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 0.65 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>G synonymous_variant 0.37 rifampicin
rpoC 766750 c.3381C>A synonymous_variant 0.34 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766813 c.3444G>C synonymous_variant 0.4 rifampicin
rpoC 766816 c.3447C>T synonymous_variant 0.38 rifampicin
rpoC 766861 c.3492G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766882 c.3513C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766942 c.3573C>G synonymous_variant 0.55 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.51 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 0.5 rifampicin
rpoC 766984 c.3615G>C synonymous_variant 0.49 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767056 c.3687C>T synonymous_variant 0.41 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767080 c.3711G>A synonymous_variant 0.6 rifampicin
rpoC 767086 c.3717C>T synonymous_variant 0.6 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767116 c.3747G>A synonymous_variant 0.65 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767163 p.Asn1265Ser missense_variant 0.73 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.72 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 1.0 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>A synonymous_variant 0.38 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775913 c.2568C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 775949 c.2532G>T synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.92 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776003 c.2476_2478delATCinsCG frameshift_variant&missense_variant 0.7 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781137 c.-423G>C upstream_gene_variant 1.0 streptomycin
rpsL 781138 c.-422_-420delCAGinsGC upstream_gene_variant 1.0 streptomycin
rpsL 781143 c.-417T>G upstream_gene_variant 1.0 streptomycin
rpsL 781147 c.-413T>C upstream_gene_variant 1.0 streptomycin
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.64 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.39 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.98 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.56 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.38 streptomycin
rpsL 781775 c.216C>T synonymous_variant 0.36 streptomycin
rpsL 781800 c.241C>T synonymous_variant 0.61 streptomycin Not assoc w R - Interim
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.62 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>A upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.76 linezolid
rplC 800693 c.-116A>T upstream_gene_variant 1.0 linezolid
rplC 800696 c.-113C>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800729 c.-80G>T upstream_gene_variant 0.72 linezolid
rplC 800738 c.-71T>G upstream_gene_variant 0.72 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.71 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 1.0 linezolid
rplC 800797 c.-12_-9delTTGGinsGTT upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800874 c.66A>G synonymous_variant 1.0 linezolid
rplC 800877 c.69A>T synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800892 c.84G>C synonymous_variant 1.0 linezolid
rplC 800893 p.Val29Ile missense_variant 0.72 linezolid
rplC 800904 c.96G>A synonymous_variant 0.72 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800922 c.114C>T synonymous_variant 0.71 linezolid
rplC 800934 c.126C>G synonymous_variant 0.72 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800958 c.150G>C synonymous_variant 1.0 linezolid
rplC 800967 c.159C>G synonymous_variant 1.0 linezolid
rplC 800976 c.168G>A synonymous_variant 0.65 linezolid
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 801004 p.Leu66Val missense_variant 1.0 linezolid
rplC 801009 c.201A>C synonymous_variant 1.0 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801033 c.225C>G synonymous_variant 1.0 linezolid
rplC 801039 c.231A>C synonymous_variant 1.0 linezolid
rplC 801045 c.237A>G synonymous_variant 1.0 linezolid
rplC 801048 c.240C>T synonymous_variant 0.68 linezolid
rplC 801054 c.246G>C synonymous_variant 1.0 linezolid
rplC 801070 p.Asp88Asn missense_variant 0.74 linezolid
rplC 801078 c.270T>C synonymous_variant 1.0 linezolid
rplC 801081 c.273C>G synonymous_variant 0.7 linezolid Not assoc w R - Interim
rplC 801083 p.Ala92Val missense_variant 0.7 linezolid
rplC 801085 p.Thr93Ala missense_variant 0.73 linezolid Uncertain significance
rplC 801094 p.Gln96Glu missense_variant 1.0 linezolid
rplC 801099 c.291T>C synonymous_variant 1.0 linezolid
rplC 801102 c.294G>C synonymous_variant 1.0 linezolid
rplC 801105 c.297A>G synonymous_variant 1.0 linezolid
rplC 801127 p.Ala107Thr missense_variant 0.69 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 0.71 linezolid
rplC 801195 c.387G>C synonymous_variant 1.0 linezolid
rplC 801201 c.393C>T synonymous_variant 1.0 linezolid
rplC 801216 c.408C>T synonymous_variant 0.66 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 0.34 linezolid
rplC 801231 c.423C>G synonymous_variant 1.0 linezolid
rplC 801249 c.441T>G synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 0.58 linezolid
rplC 801282 c.474G>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 0.69 linezolid
rplC 801309 c.501C>G synonymous_variant 0.66 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801330 c.522G>A synonymous_variant 0.65 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801375 p.Asn189Lys missense_variant 0.66 linezolid
rplC 801393 c.585G>A synonymous_variant 0.36 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 0.39 linezolid
rplC 801405 c.597T>C synonymous_variant 0.58 linezolid
rplC 801408 c.600C>G synonymous_variant 0.56 linezolid
rplC 801417 c.609T>C synonymous_variant 0.6 linezolid
rplC 801420 c.612A>G synonymous_variant 0.38 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801438 c.630T>C synonymous_variant 0.56 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 1.0 linezolid
fbiC 1303440 c.510G>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303458 c.528G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303492 c.562T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303500 c.570C>T synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1303501 c.571C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303530 c.600G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303554 c.624G>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303596 c.666G>A synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1303629 c.699C>T synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1303650 c.720G>A synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1303665 c.735G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303692 c.762G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>T synonymous_variant 0.52 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303743 c.813C>A synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303746 p.Asp272Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303755 c.825T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303830 c.900C>T synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303908 c.978C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303932 c.1002G>T synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303938 c.1008C>T synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303939 c.1009C>T synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303966 c.1036C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304019 c.1089C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304068 p.Val380Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304075 p.Ala382Asp missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304104 c.1174C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304112 c.1182G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304130 c.1200G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304157 c.1227G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304166 c.1236A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304173 p.Val415Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304187 c.1257T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304227 p.Met433Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304652 c.1722C>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304655 c.1725C>T synonymous_variant 0.75 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304658 c.1728C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304682 c.1752C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304710 p.Ala594Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304742 c.1812T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304805 c.1875G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304826 c.1896G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304871 c.1941G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1304896 c.1966C>T synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304985 c.2055G>A synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305039 c.2109G>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305075 c.2145T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305090 c.2160C>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305105 c.2175G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305114 c.2184T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305234 c.2304G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305279 p.His783Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305375 c.2445C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1305381 c.2451G>A synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1305399 c.2469A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1305422 p.Ala831Glu missense_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1305435 c.2505G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305447 c.2517C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1305453 c.2523C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>G synonymous_variant 0.64 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364826 c.414C>A synonymous_variant 0.33 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364845 c.433C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364895 p.Glu161Asp missense_variant 0.76 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 c.510G>A synonymous_variant 0.74 pyrazinamide
sigE 1364942 p.Tyr177Phe missense_variant 1.0 pyrazinamide
sigE 1364950 c.538_540delGCAinsTG frameshift_variant&stop_gained 0.98 pyrazinamide Uncertain significance
sigE 1364961 c.549A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364962 c.550_552delCCTinsGC frameshift_variant&missense_variant 0.83 pyrazinamide Uncertain significance
sigE 1364976 c.564T>G synonymous_variant 1.0 pyrazinamide
sigE 1364979 c.567C>G synonymous_variant 0.86 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.76 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.83 pyrazinamide
atpE 1460804 c.-241T>C upstream_gene_variant 0.83 bedaquiline
atpE 1460813 c.-232C>T upstream_gene_variant 0.83 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 0.79 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.73 bedaquiline
atpE 1460837 c.-208C>T upstream_gene_variant 0.73 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460843 c.-202G>C upstream_gene_variant 0.75 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.73 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.87 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460918 c.-127A>G upstream_gene_variant 1.0 bedaquiline
atpE 1461086 c.42A>C synonymous_variant 1.0 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 1.0 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 1.0 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 1.0 bedaquiline
atpE 1461131 c.87T>A synonymous_variant 1.0 bedaquiline
atpE 1461132 c.88_90delGTCinsAT frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461137 c.93C>T synonymous_variant 0.85 bedaquiline
atpE 1461146 c.102G>A synonymous_variant 0.85 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461150 c.106_108delATCinsGG frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.85 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673523 c.-679G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673542 c.-660C>T upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673559 c.-643C>T upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.42 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673602 c.-600C>T upstream_gene_variant 0.38 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 0.56 ethionamide
isoniazid
inhA 1673613 c.-589C>G upstream_gene_variant 0.44 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.56 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 1.0 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 0.53 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 1.0 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673670 c.-532G>A upstream_gene_variant 0.44 ethionamide
isoniazid
inhA 1673673 c.-529C>T upstream_gene_variant 0.51 ethionamide
isoniazid
inhA 1673679 c.-523T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673682 c.-520G>C upstream_gene_variant 0.45 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673709 c.-493C>A upstream_gene_variant 0.44 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsGG frameshift_variant&missense_variant 0.55 ethionamide
isoniazid
inhA 1673715 c.-487C>G upstream_gene_variant 0.57 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673718 c.-484G>C upstream_gene_variant 0.6 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673750 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
inhA 1673781 c.-421C>G upstream_gene_variant 0.67 ethionamide
isoniazid
inhA 1673784 c.-418G>C upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 1.0 ethionamide
isoniazid
fabG1 1673830 p.Lys131Arg missense_variant 1.0 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 0.78 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673859 c.-343G>C upstream_gene_variant 0.75 ethionamide
isoniazid
inhA 1673862 c.-340C>T upstream_gene_variant 0.76 ethionamide
isoniazid
fabG1 1673870 p.Ser144Thr missense_variant 0.98 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.66 ethionamide
isoniazid
inhA 1673958 c.-244G>A upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1673970 c.-232C>G upstream_gene_variant 0.39 ethionamide
isoniazid
inhA 1673973 c.-229G>C upstream_gene_variant 0.39 ethionamide
isoniazid Uncertain significance
inhA 1673982 c.-220G>T upstream_gene_variant 0.37 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 0.63 ethionamide
isoniazid
inhA 1674006 c.-196T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674015 c.-187C>A upstream_gene_variant 0.42 ethionamide
isoniazid
fabG1 1674016 p.Ala193Ser missense_variant 0.42 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.38 ethionamide
isoniazid
fabG1 1674037 p.Gln200Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674072 c.-130C>G upstream_gene_variant 0.6 ethionamide
isoniazid
fabG1 1674079 c.640_642delCCCinsGA frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674090 c.-112C>G upstream_gene_variant 0.37 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674117 c.-85C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674279 c.78A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674280 p.Arg27Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674285 c.84A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674295 p.Gln32Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674300 c.99C>G synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674303 c.102C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674307 c.106C>T synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674315 c.114C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674318 c.117C>G synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674321 c.120G>C synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674336 c.135G>T synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674337 c.136C>T synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid
inhA 1674367 p.Ala56Gln missense_variant 0.69 ethionamide
isoniazid
inhA 1674378 c.177G>C synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674381 c.180G>T synonymous_variant 0.74 ethionamide
isoniazid
inhA 1674387 c.186A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674406 p.Glu69Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674414 c.213G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674416 p.Ala72Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1674419 p.Ser73Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674421 c.220T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674426 c.225C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674428 p.Gly76Asp missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674441 c.240G>A synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674450 c.249G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674507 c.306G>A synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674537 c.336C>A synonymous_variant 0.73 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.65 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 c.400C>T synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674609 c.408G>C synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674621 c.420C>G synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674639 c.438C>G synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 0.66 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 0.66 ethionamide
isoniazid
inhA 1674738 c.537C>G synonymous_variant 0.37 ethionamide
isoniazid
inhA 1674741 c.540C>G synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674746 p.Tyr182Phe missense_variant 0.64 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674804 c.603G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid
inhA 1674816 c.615T>G synonymous_variant 0.49 ethionamide
isoniazid
inhA 1674825 c.624C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674828 c.627G>A synonymous_variant 0.46 ethionamide
isoniazid
inhA 1674832 p.Ala211Thr missense_variant 0.47 ethionamide
isoniazid
inhA 1674840 c.639C>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674850 c.649C>T synonymous_variant 0.51 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674855 c.654C>G synonymous_variant 0.45 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674882 c.681G>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674888 c.687C>G synonymous_variant 0.49 ethionamide
isoniazid
inhA 1674900 c.699G>A synonymous_variant 0.44 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674915 c.714C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674933 c.732G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674934 p.Leu245Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1675008 c.807C>T synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833250 c.-292A>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833256 c.-286C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833284 c.-258C>T upstream_gene_variant 1.0 pyrazinamide
rpsA 1833288 c.-254T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833292 c.-250C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833295 c.-247C>A upstream_gene_variant 1.0 pyrazinamide
rpsA 1833306 c.-236G>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833319 c.-223C>T upstream_gene_variant 1.0 pyrazinamide
rpsA 1833331 c.-211G>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833337 c.-205G>T upstream_gene_variant 1.0 pyrazinamide
rpsA 1833346 c.-196C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833349 c.-193C>T upstream_gene_variant 1.0 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 0.73 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833673 c.132C>A synonymous_variant 0.33 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
rpsA 1833790 c.249T>A synonymous_variant 0.41 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.59 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.41 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.57 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.44 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833871 c.330G>A synonymous_variant 0.42 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.38 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.66 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.34 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.68 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.68 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.7 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 0.67 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.66 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.36 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.39 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.4 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.64 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.33 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.34 pyrazinamide
rpsA 1834465 c.924T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834504 c.963G>T synonymous_variant 0.34 pyrazinamide
rpsA 1834525 c.984G>A synonymous_variant 0.66 pyrazinamide
rpsA 1834528 c.987T>G synonymous_variant 0.65 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834561 c.1020C>T synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
rpsA 1834573 c.1032G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834585 c.1044C>G synonymous_variant 0.35 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.99 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834669 c.1128G>C synonymous_variant 0.38 pyrazinamide
rpsA 1834675 c.1134C>T synonymous_variant 0.56 pyrazinamide
rpsA 1834678 c.1137C>G synonymous_variant 0.56 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.98 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.57 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.46 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.98 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834767 p.Lys409Thr missense_variant 0.54 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.4 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853369 c.-237C>T upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853381 c.-225C>T upstream_gene_variant 0.43 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>A upstream_gene_variant 0.45 linezolid
tsnR 1853430 c.-176C>T upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 1.0 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 1.0 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 1.0 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853474 c.-132C>T upstream_gene_variant 0.47 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 1.0 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 1.0 linezolid
tsnR 1853510 c.-96G>C upstream_gene_variant 0.47 linezolid
tsnR 1853519 c.-87C>T upstream_gene_variant 0.43 linezolid
tsnR 1853525 c.-81G>C upstream_gene_variant 1.0 linezolid
tsnR 1853528 c.-78G>C upstream_gene_variant 1.0 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 1.0 linezolid
tsnR 1853540 c.-66A>G upstream_gene_variant 1.0 linezolid
tlyA 1918413 c.474C>T synonymous_variant 0.79 capreomycin
tlyA 1918417 c.478T>C synonymous_variant 1.0 capreomycin
tlyA 1918422 c.483T>C synonymous_variant 1.0 capreomycin
tlyA 1918441 p.Val168Thr missense_variant 0.69 capreomycin
tlyA 1918446 c.507A>C synonymous_variant 1.0 capreomycin
tlyA 1918455 c.516G>C synonymous_variant 0.69 capreomycin
tlyA 1918457 p.Arg173Pro missense_variant 1.0 capreomycin
tlyA 1918464 c.525C>G synonymous_variant 1.0 capreomycin
tlyA 1918476 c.537A>C synonymous_variant 1.0 capreomycin
tlyA 1918477 p.Leu180Met missense_variant 1.0 capreomycin
bacA 2064969 c.-241T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064981 c.-253G>C upstream_gene_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064990 c.-262G>C upstream_gene_variant 0.48 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.52 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064996 c.-268G>T upstream_gene_variant 0.56 streptomycin
kanamycin
capreomycin
amikacin
bacA 2065008 c.-280C>G upstream_gene_variant 0.41 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101714 c.1329A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101722 c.1321C>A synonymous_variant 0.53 ethionamide
delamanid
isoniazid
ndh 2101723 c.1320G>A synonymous_variant 0.53 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2101726 c.1317A>C synonymous_variant 0.45 ethionamide
delamanid
isoniazid
ndh 2101732 c.1311T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101735 c.1308A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101744 c.1299C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>C synonymous_variant 0.5 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101789 c.1254G>C synonymous_variant 0.47 ethionamide
delamanid
isoniazid
ndh 2101800 c.1243C>T synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101810 c.1231_1233delATCinsCG frameshift_variant&missense_variant 0.42 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101833 c.1210C>T synonymous_variant 0.58 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101834 c.1209C>T synonymous_variant 1.0 ethionamide
delamanid Not assoc w R - Interim
isoniazid
ndh 2101837 c.1206G>C synonymous_variant 0.61 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2101840 c.1203G>T synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2101858 p.Ile395Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101863 c.1180C>T synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2101867 c.1176C>G synonymous_variant 0.64 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101876 c.1167C>G synonymous_variant 0.36 ethionamide
delamanid
isoniazid
ndh 2101888 c.1153_1155delGTTinsCG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101891 c.1152C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.55 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101915 c.1128T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101920 c.1123A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101930 c.1113C>G synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101948 c.1095C>T synonymous_variant 0.36 ethionamide
delamanid
isoniazid
ndh 2101957 c.1086C>T synonymous_variant 0.34 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2101966 c.1077T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101969 p.Glu358Ala missense_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2101972 c.1071G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101978 c.1063_1065delAACinsGT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101984 c.1059C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101987 p.Ala352Gly missense_variant 0.48 ethionamide
delamanid
isoniazid
ndh 2101999 c.1044G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102009 p.Ser345Asn missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102020 c.1023A>G synonymous_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2102023 p.Ala340Gly missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102026 c.1017G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102035 c.1008C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102038 c.1005C>T synonymous_variant 0.58 ethionamide
delamanid
isoniazid
ndh 2102050 c.993T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102059 c.984T>C synonymous_variant 0.44 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102068 c.975T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102077 c.966T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102086 c.957G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102103 p.Tyr314His missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102104 c.939G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102107 c.936C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102128 c.915G>A synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2102131 c.910_912delCAAinsAG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102137 c.906G>C synonymous_variant 0.88 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102148 c.895C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102158 c.885T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102162 p.Arg294Ser missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102164 c.879A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102167 c.876A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102176 c.867T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102184 c.859A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102193 p.Arg284Gly missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102194 c.849T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102218 c.825C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>G synonymous_variant 0.58 ethionamide
delamanid
isoniazid
ndh 2102245 c.798C>T synonymous_variant 0.54 ethionamide
delamanid
isoniazid
ndh 2102251 c.792C>T synonymous_variant 0.75 ethionamide
delamanid
isoniazid
ndh 2102269 c.774C>G synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102274 p.Ile257Leu missense_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102314 c.729C>A synonymous_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102323 c.720C>T synonymous_variant 0.68 ethionamide
delamanid
isoniazid
ndh 2102332 c.709_711delCAGinsGA frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102337 c.706T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid
ndh 2102341 c.702C>A synonymous_variant 0.68 ethionamide
delamanid
isoniazid
ndh 2102344 p.Ala233Arg missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102366 p.Ala226Glu missense_variant 1.0 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102368 c.675C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102374 c.669G>A synonymous_variant 0.41 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102377 c.666A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102382 c.661C>T synonymous_variant 0.4 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102389 c.654G>T synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102392 c.651C>G synonymous_variant 0.39 ethionamide
delamanid
isoniazid
ndh 2102401 c.642T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102407 c.636T>C synonymous_variant 0.53 ethionamide
delamanid
isoniazid
ndh 2102416 c.627G>T synonymous_variant 0.46 ethionamide
delamanid
isoniazid
ndh 2102425 c.618G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102434 p.His203Gln missense_variant 0.47 ethionamide
delamanid
isoniazid
ndh 2102437 c.606G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102443 c.600A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102450 p.Lys198Arg missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102460 p.His195Tyr missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102469 c.574C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102470 c.573G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102473 c.570C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102482 c.561A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102791 c.252A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102800 c.243T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102809 c.234G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102812 c.231T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102830 c.213G>C synonymous_variant 0.58 ethionamide
delamanid
isoniazid
ndh 2102836 c.207T>C synonymous_variant 0.42 ethionamide
delamanid
isoniazid
ndh 2102842 c.201A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102845 c.198A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102848 c.195G>A synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2102857 c.186T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102866 c.177C>A synonymous_variant 0.59 ethionamide
delamanid
isoniazid
ndh 2102872 c.171A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102883 c.160C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 0.69 ethionamide
delamanid
isoniazid
ndh 2102902 c.141C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102911 c.132G>C synonymous_variant 0.75 ethionamide
delamanid
isoniazid
katG 2155086 c.1026G>A synonymous_variant 0.91 isoniazid
katG 2155113 c.999C>G synonymous_variant 1.0 isoniazid
katG 2155119 p.Ser331Thr missense_variant 1.0 isoniazid
katG 2155131 c.981A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155144 p.Asn323Pro missense_variant 1.0 isoniazid
katG 2155152 c.960A>C synonymous_variant 1.0 isoniazid
katG 2155155 c.957C>G synonymous_variant 1.0 isoniazid
katG 2155185 c.927T>C synonymous_variant 1.0 isoniazid
katG 2155188 p.Thr308Lys missense_variant 1.0 isoniazid
katG 2155191 c.921A>C synonymous_variant 1.0 isoniazid
katG 2155203 c.909G>C synonymous_variant 1.0 isoniazid
katG 2155596 c.516G>C synonymous_variant 1.0 isoniazid
katG 2155605 c.507C>A synonymous_variant 0.93 isoniazid
katG 2155617 c.495T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155632 c.480A>C synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155659 c.453C>G synonymous_variant 0.92 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155698 c.414C>T synonymous_variant 0.92 isoniazid Not assoc w R - Interim
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>C synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
katG 2155740 p.Gly124Gln missense_variant 1.0 isoniazid
katG 2155747 p.Ala122Gly missense_variant 1.0 isoniazid
katG 2155765 p.His116Phe missense_variant 1.0 isoniazid
katG 2155776 c.336C>G synonymous_variant 0.87 isoniazid
katG 2155785 c.327T>C synonymous_variant 1.0 isoniazid
pncA 2289967 c.-726C>T upstream_gene_variant 0.91 pyrazinamide
pncA 2289970 c.-729C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289973 c.-732T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289990 c.-749A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289994 c.-753A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.75 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.76 pyrazinamide
pncA 2290032 c.-791A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 0.76 pyrazinamide
pncA 2290038 c.-797G>T upstream_gene_variant 1.0 pyrazinamide
pncA 2290042 c.-803_-801delGCTinsTG upstream_gene_variant 1.0 pyrazinamide
pncA 2290071 c.-830A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290072 c.-831T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290081 c.-840C>T upstream_gene_variant 0.82 pyrazinamide
pncA 2290087 c.-846T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290099 c.-858C>T upstream_gene_variant 0.83 pyrazinamide
pncA 2290102 c.-861G>A upstream_gene_variant 1.0 pyrazinamide
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.31 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 1.0 isoniazid
kasA 2518028 c.-87G>A upstream_gene_variant 0.88 isoniazid
kasA 2518031 c.-84G>C upstream_gene_variant 1.0 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 1.0 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 1.0 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 1.0 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 1.0 isoniazid
kasA 2518053 c.-62_-60delATTinsTG upstream_gene_variant 1.0 isoniazid
kasA 2518059 c.-56T>A upstream_gene_variant 0.81 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 1.0 isoniazid
kasA 2518088 c.-27T>C upstream_gene_variant 1.0 isoniazid
kasA 2518089 c.-26C>A upstream_gene_variant 1.0 isoniazid
kasA 2518100 c.-15T>G upstream_gene_variant 1.0 isoniazid
kasA 2518103 c.-12G>A upstream_gene_variant 1.0 isoniazid
kasA 2518106 c.-9C>G upstream_gene_variant 1.0 isoniazid
kasA 2518109 c.-6G>C upstream_gene_variant 1.0 isoniazid
kasA 2518110 c.-5_-4delTCinsAG upstream_gene_variant 1.0 isoniazid
kasA 2518120 c.6T>C synonymous_variant 1.0 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 1.0 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518475 c.361A>C synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518483 c.369C>G synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518513 c.399C>T synonymous_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518525 c.411G>A synonymous_variant 0.68 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>G synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518624 c.510C>G synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518630 c.516G>A synonymous_variant 0.32 isoniazid
kasA 2518633 c.519G>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>A synonymous_variant 1.0 isoniazid
kasA 2518651 c.537C>G synonymous_variant 1.0 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.67 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518671 p.Val186Ala missense_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.67 isoniazid
kasA 2518688 p.Val192Phe missense_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>G synonymous_variant 1.0 isoniazid
kasA 2518723 c.609G>A synonymous_variant 0.61 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.48 isoniazid
kasA 2518768 c.654C>T synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>G synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>T synonymous_variant 1.0 isoniazid
kasA 2518813 p.Asp233Glu missense_variant 0.5 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.95 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2519056 c.942G>A synonymous_variant 1.0 isoniazid
kasA 2519072 c.958_960delGCCinsAG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2519077 c.963G>C synonymous_variant 1.0 isoniazid
kasA 2519095 c.981C>G synonymous_variant 1.0 isoniazid
kasA 2519101 c.987C>G synonymous_variant 1.0 isoniazid
kasA 2519104 c.990T>C synonymous_variant 1.0 isoniazid
kasA 2519107 c.993T>C synonymous_variant 1.0 isoniazid
kasA 2519128 c.1014G>A synonymous_variant 1.0 isoniazid
kasA 2519134 c.1020G>A synonymous_variant 0.63 isoniazid
kasA 2519137 c.1023T>C synonymous_variant 1.0 isoniazid
kasA 2519140 c.1026G>T synonymous_variant 0.32 isoniazid
kasA 2519167 c.1053T>C synonymous_variant 1.0 isoniazid
kasA 2519170 c.1056G>A synonymous_variant 0.85 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 1.0 isoniazid
kasA 2519176 c.1062G>A synonymous_variant 1.0 isoniazid
kasA 2519179 c.1065G>T synonymous_variant 1.0 isoniazid
kasA 2519182 c.1068G>T synonymous_variant 1.0 isoniazid
kasA 2519191 c.1077G>A synonymous_variant 1.0 isoniazid
kasA 2519192 c.1078C>T synonymous_variant 1.0 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 1.0 isoniazid
kasA 2519200 c.1086G>T synonymous_variant 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519212 c.1098C>G synonymous_variant 1.0 isoniazid
kasA 2519215 c.1101C>A synonymous_variant 1.0 isoniazid
kasA 2519221 c.1107G>A synonymous_variant 0.81 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 1.0 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 1.0 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 1.0 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 1.0 isoniazid
kasA 2519287 c.1173T>C synonymous_variant 0.61 isoniazid
kasA 2519295 p.Tyr394Phe missense_variant 1.0 isoniazid
kasA 2519299 c.1185C>T synonymous_variant 1.0 isoniazid
kasA 2519305 c.1191A>C synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
kasA 2519332 c.1218C>T synonymous_variant 0.45 isoniazid
kasA 2519338 c.1224T>C synonymous_variant 1.0 isoniazid
kasA 2519344 c.1230G>A synonymous_variant 0.52 isoniazid
kasA 2519347 c.1233T>C synonymous_variant 1.0 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 1.0 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 1.0 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 1.0 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 1.0 isoniazid
ahpC 2726322 c.130_132delCCAinsGC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
ahpC 2726336 c.144G>C synonymous_variant 1.0 isoniazid
ahpC 2726339 c.147G>C synonymous_variant 1.0 isoniazid
ahpC 2726342 c.150G>C synonymous_variant 0.75 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 1.0 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 1.0 isoniazid
ahpC 2726378 c.186T>C synonymous_variant 1.0 isoniazid
ahpC 2726387 c.195C>T synonymous_variant 1.0 isoniazid
ahpC 2726390 c.198G>C synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
ahpC 2726579 c.387T>C synonymous_variant 1.0 isoniazid
ahpC 2726591 c.399C>G synonymous_variant 1.0 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726601 c.409_411delATCinsCG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
ahpC 2726606 c.414C>G synonymous_variant 1.0 isoniazid
ahpC 2726627 c.435G>A synonymous_variant 0.85 isoniazid
ahpC 2726633 c.441C>T synonymous_variant 0.85 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 1.0 isoniazid
ahpC 2726642 c.450C>A synonymous_variant 0.81 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.81 isoniazid
ahpC 2726648 c.456T>A synonymous_variant 1.0 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 1.0 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726666 c.474C>G synonymous_variant 0.75 isoniazid
ahpC 2726669 p.Asp159Glu missense_variant 1.0 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 1.0 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 1.0 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 1.0 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
folC 2746477 c.1122T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746492 c.1107G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746495 c.1102_1104delCATinsGC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2746498 c.1101G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746507 c.1092A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746510 c.1089A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746516 c.1083T>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746519 p.Ser360Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746525 c.1074G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747131 c.468C>T synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747239 c.360T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747245 c.354G>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747260 c.337_339delAAGinsCA frameshift_variant&missense_variant 0.93 para-aminosalicylic_acid
folC 2747274 p.Ser109Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747314 c.285A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747341 c.258C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747347 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747363 p.Ala79Val missense_variant 1.0 para-aminosalicylic_acid
folC 2747371 c.228C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 1.0 para-aminosalicylic_acid
folC 2747404 c.195G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747410 c.187_189delAGCinsT frameshift_variant&synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747428 c.171G>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782393 c.1650C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782396 c.1647G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782399 c.1644T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782405 c.1638A>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782408 c.1635T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782411 c.1632C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782417 c.1626C>G synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782420 c.1623T>G synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782423 c.1620C>T synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782432 c.1611G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782435 c.1608G>A synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782441 c.1602G>A synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>T synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 p.Asp516Glu missense_variant 0.73 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782510 c.1533G>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1504_1506delCTTinsTG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782552 c.1491C>T synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782561 c.1482G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783026 c.1017C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783048 p.Asp332Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783053 c.990C>T synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783062 c.981C>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783080 c.963G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783119 c.924G>A synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783128 c.915C>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 0.8 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783182 c.861C>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783203 c.840C>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783206 c.837G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783218 c.825C>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783244 p.Thr267Ala missense_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783341 c.702C>G synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783347 c.696C>A synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.670_672delGAAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783415 c.628C>T synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783416 c.625_627delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783419 c.624G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.616_618delCCCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783432 p.Ser204Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783455 c.588G>A synonymous_variant 0.72 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783536 c.507G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783569 c.474C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783695 c.348C>T synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783704 c.339C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783770 c.273G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783785 c.258C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783800 c.243G>A synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783845 c.196_198delACCinsTT frameshift_variant&missense_variant 0.64 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783857 c.186C>T synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783926 c.117C>T synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783944 c.99G>A synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783956 c.87T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784441 c.-399G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784465 c.-423T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784468 c.-426C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784476 c.-434A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784493 c.-451C>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784510 c.-470_-468delAGCinsGCG upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784513 c.-471C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784519 c.-477G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784522 c.-480C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784525 c.-483G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784546 c.-504G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784551 c.-509G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2860191 c.228G>A synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860197 c.222T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860203 c.216A>G synonymous_variant 0.91 clofazimine
bedaquiline
pepQ 2860218 c.201A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860222 p.Ser66Glu missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860233 c.186T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860272 p.Glu49Asp missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860275 c.144T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2860293 c.126A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860309 p.Ser37Thr missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860317 c.102A>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860392 p.Lys9Asn missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860401 c.18T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860407 c.12C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860446 c.-28T>A upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860456 c.-39_-38delAGinsTC upstream_gene_variant 0.73 clofazimine
bedaquiline
pepQ 2860459 c.-41T>C upstream_gene_variant 0.73 clofazimine
bedaquiline
pepQ 2860475 c.-57C>T upstream_gene_variant 0.73 clofazimine
bedaquiline
pepQ 2860480 c.-62G>A upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860483 c.-66_-65delGAinsAT upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860490 c.-72G>C upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860499 c.-81C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860503 c.-85G>C upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860509 c.-91G>A upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860517 c.-99C>T upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860523 c.-105T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
Rv2681 2996350 c.-389C>A upstream_gene_variant 1.0 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 1.0 capreomycin
Rv2681 2996368 c.-371T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 1.0 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 1.0 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996404 c.-335T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996407 c.-332C>A upstream_gene_variant 0.57 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 1.0 capreomycin
Rv2680 2996438 c.334_336delTCGinsCC frameshift_variant&missense_variant 0.6 capreomycin Uncertain significance
Rv2681 2996443 c.-296T>C upstream_gene_variant 0.6 capreomycin
Rv2680 2996446 c.342A>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996470 c.-269G>A upstream_gene_variant 0.57 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 1.0 capreomycin
Rv2681 2997121 p.Arg128Gln missense_variant 0.5 capreomycin
Rv2681 2997131 c.393G>C synonymous_variant 0.5 capreomycin
Rv2681 2997134 c.396A>G synonymous_variant 1.0 capreomycin
Rv2681 2997137 c.399C>T synonymous_variant 0.47 capreomycin
Rv2681 2997146 c.408G>A synonymous_variant 1.0 capreomycin
Rv2681 2997149 c.411T>G synonymous_variant 1.0 capreomycin
Rv2681 2997158 c.420C>G synonymous_variant 1.0 capreomycin
Rv2681 2997167 c.429G>A synonymous_variant 0.45 capreomycin
Rv2681 2997173 p.Asp145Glu missense_variant 1.0 capreomycin
Rv2681 2997176 c.438A>G synonymous_variant 1.0 capreomycin
Rv2681 2997179 c.441G>C synonymous_variant 0.45 capreomycin
Rv2681 2997185 c.447G>C synonymous_variant 0.55 capreomycin
Rv2681 2997188 c.450G>C synonymous_variant 0.45 capreomycin
Rv2681 2997189 p.Ala151Thr missense_variant 1.0 capreomycin
Rv2681 2997197 c.459C>G synonymous_variant 0.56 capreomycin
Rv2681 2997204 c.466_468delTTAinsCG frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997209 c.471T>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2997212 c.474A>T synonymous_variant 1.0 capreomycin
Rv2681 2997213 p.Leu159Ser missense_variant 1.0 capreomycin
Rv2681 2997222 p.Thr162Ala missense_variant 1.0 capreomycin
Rv2681 2997236 c.498C>G synonymous_variant 1.0 capreomycin
Rv2752c 3064809 c.1383C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064815 c.1377T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064818 c.1374C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064830 p.Ala454Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064838 c.1354T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064839 c.1353C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064860 c.1332G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064872 c.1320T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064877 p.Ser439Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064885 p.Ala436Gly missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064889 c.1302delC frameshift_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064894 p.Ala433Gly missense_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>C synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064932 c.1260T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064935 c.1257A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064944 c.1248G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064947 c.1245A>G synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064950 c.1242C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064956 c.1236T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064962 c.1230C>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065013 c.1179G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065018 p.Asn392His missense_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065019 c.1173C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065031 c.1161G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065048 c.1144C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065055 c.1137T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065097 c.1095C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065442 c.750T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065451 c.741G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065481 c.711T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065496 c.696G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065502 p.Asp230Glu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.682_684delGGTinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065511 c.681G>C synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065517 c.675C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065520 c.672G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065532 c.660A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065553 c.639A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065556 c.636G>T synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065559 c.633C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065570 p.Ile208Val missense_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066429 c.-238G>C upstream_gene_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>G upstream_gene_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066435 c.-245_-244delGTinsCG upstream_gene_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066453 c.-262G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-268T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-274G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066468 c.-277C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066476 c.-285C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066480 c.-289C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066483 c.-292T>C upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066537 c.-346C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066546 c.-355C>G upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066552 c.-361C>T upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066578 c.-387A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066590 c.-399A>G upstream_gene_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066653 c.-462A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066660 c.-470_-469delCCinsGG upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066672 c.-481G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066676 c.-485C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066690 c.-499C>T upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066696 c.-505T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066699 c.-508C>G upstream_gene_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066704 c.-513C>G upstream_gene_variant 0.76 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066707 c.-516A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066732 c.-541C>G upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066741 c.-550T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066744 c.-553C>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066747 c.-558_-556delCAAinsATC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066756 c.-567_-565delCGGinsAC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066765 c.-574G>T upstream_gene_variant 0.63 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066768 c.-577G>A upstream_gene_variant 0.63 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066826 c.-636_-635delAAinsCG upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067232 c.714C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067243 c.703C>T synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067244 c.702C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067271 c.675G>T synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067277 c.669C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067280 p.Val222Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067284 p.Ala221Asp missense_variant 1.0 para-aminosalicylic_acid
thyX 3067288 p.Ala220Thr missense_variant 0.75 para-aminosalicylic_acid
thyX 3067295 c.651C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067340 c.606G>A synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067360 p.Ile196Val missense_variant 0.36 para-aminosalicylic_acid
thyX 3067376 c.570G>C synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067388 c.558C>G synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067412 c.534C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067457 c.489C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067460 c.484_486delCTGinsTA frameshift_variant&synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067463 c.481_483delATCinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 1.0 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 1.0 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067586 c.360C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067598 c.348C>G synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067601 c.345G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067613 c.333G>A synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067622 c.324C>T synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067640 c.306G>C synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067643 c.303C>T synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067649 c.297C>T synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067680 p.Cys89Leu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067706 c.240C>T synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067716 p.Ser77Asn missense_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067762 c.184C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067840 p.Val36Ile missense_variant 0.34 para-aminosalicylic_acid
thyX 3067843 c.103C>T synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067847 c.97_99delCCCinsGG frameshift_variant&missense_variant 0.64 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.48 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067925 c.21G>A synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067939 p.Glu3Lys missense_variant 0.48 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 1.0 para-aminosalicylic_acid
thyA 3073884 c.588C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073896 c.576C>G synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073980 c.492C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3074052 p.Arg140His missense_variant 0.56 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3074229 c.243C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074244 c.228A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074254 p.His73Arg missense_variant 0.6 para-aminosalicylic_acid
thyA 3074262 p.Gly70Ala missense_variant 1.0 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 1.0 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 0.72 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074305 p.Ala56Val missense_variant 1.0 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074316 c.154_156delTTCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3074322 c.150C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074325 c.147A>G synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074342 c.130C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074346 c.126C>T synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 1.0 para-aminosalicylic_acid
ald 3087704 c.885T>C synonymous_variant 1.0 cycloserine
ald 3087755 c.936G>A synonymous_variant 0.55 cycloserine
ald 3087770 c.951G>C synonymous_variant 1.0 cycloserine
ald 3087779 c.960T>C synonymous_variant 1.0 cycloserine
ald 3087788 c.969G>A synonymous_variant 0.58 cycloserine
ald 3087791 c.972T>C synonymous_variant 1.0 cycloserine
ald 3087799 p.His327Arg missense_variant 1.0 cycloserine
lpqB 3623360 c.1551A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623363 c.1548T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623366 c.1545T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623379 p.Ala511Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623390 c.1521C>T synonymous_variant 0.69 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 0.46 bedaquiline
rifampicin
lpqB 3623417 c.1494A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623428 c.1483T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623441 p.Ser490Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623447 c.1464G>C synonymous_variant 0.53 bedaquiline
rifampicin
lpqB 3623456 c.1455T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623459 c.1452G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623480 c.1431C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623486 c.1425G>A synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623489 c.1422C>T synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623492 c.1419T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623512 p.Gly467Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623519 c.1392C>T synonymous_variant 0.74 bedaquiline
rifampicin
lpqB 3623528 c.1383G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623531 c.1380T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624365 c.546T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624368 c.543C>G synonymous_variant 0.81 bedaquiline
rifampicin
lpqB 3624377 c.534C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624386 c.525C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624452 c.459T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624482 c.429T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624485 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624488 c.421_423delTCCinsCG frameshift_variant&synonymous_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624491 c.420G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624656 c.255C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 0.72 bedaquiline
rifampicin Uncertain significance
lpqB 3624695 c.216C>T synonymous_variant 0.74 bedaquiline
rifampicin
lpqB 3624698 c.213G>A synonymous_variant 0.74 bedaquiline
rifampicin
lpqB 3624704 c.207G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624716 c.195G>C synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624724 p.Ala63Thr missense_variant 0.72 bedaquiline
rifampicin
lpqB 3624725 c.186G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624760 c.151C>T synonymous_variant 0.79 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624782 p.Ser43Thr missense_variant 0.91 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624807 p.Val35Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624812 c.99T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624815 c.96A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3625558 c.-648C>T upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.73 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 0.4 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 0.41 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625660 c.954C>T synonymous_variant 0.57 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.47 bedaquiline
rifampicin
lpqB 3625672 c.-762G>C upstream_gene_variant 0.53 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625678 c.-768C>G upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625684 c.-774G>C upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.43 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.41 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625753 c.859_861delGCCinsAG frameshift_variant&missense_variant 0.59 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.64 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625837 c.-927C>A upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625852 c.-942A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625855 p.Glu253Asp missense_variant 0.81 bedaquiline
rifampicin
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625906 c.-996G>A upstream_gene_variant 0.44 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 0.56 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626073 p.Ile181Val missense_variant 0.82 bedaquiline
rifampicin
mtrB 3626077 c.537C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626083 c.531G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626092 c.522T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626095 p.Glu173Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626101 p.Gln171His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626107 c.507G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626122 c.490_492delGCCinsTG frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626125 c.489C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626131 c.483G>C synonymous_variant 0.45 bedaquiline
rifampicin
mtrB 3626146 c.468C>T synonymous_variant 0.55 bedaquiline
rifampicin
mtrB 3626154 c.460C>T synonymous_variant 0.45 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626155 c.457_459delGCGinsTC frameshift_variant&missense_variant 0.45 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626158 c.456C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626170 c.444T>C synonymous_variant 0.47 bedaquiline
rifampicin
mtrB 3626182 c.432C>G synonymous_variant 0.47 bedaquiline
rifampicin
mtrB 3626188 c.424_426delTCTinsAC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626191 c.423C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626194 c.420T>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626206 c.408T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626209 c.405T>C synonymous_variant 0.44 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626218 p.Met132Ile missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626230 c.384T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.38 bedaquiline
rifampicin
mtrB 3626705 c.-92G>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3626711 c.-98T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626720 c.-107G>A upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626750 c.-137T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.41 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626849 c.-236C>T upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626891 c.-278G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626915 c.-302C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626957 c.-344G>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627065 c.-452G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627073 c.277C>T synonymous_variant 0.73 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627143 c.-530G>C upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627200 c.-587C>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 0.99 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627263 c.-650C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627277 c.73C>T synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627296 c.-683T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.71 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627362 c.-749A>T upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrA 3627861 c.-512C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627875 c.-526G>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrA 3627884 c.-535A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
fbiB 3640797 c.-738T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640808 p.Met89Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640810 p.Gln90Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640816 c.-719C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640820 p.Val93Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640827 c.-708T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640830 c.288C>T synonymous_variant 0.68 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiA 3640850 p.Glu103Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640854 c.-681C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640857 c.-678G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640860 c.318C>T synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiB 3640878 c.-657T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640899 c.-636G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640914 c.-621C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640917 c.-618G>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3640920 c.-615A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640930 p.Glu130Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640938 c.-597A>G upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3640944 c.-591T>C upstream_gene_variant 0.91 clofazimine
pretomanid
delamanid
fbiB 3640956 c.-579G>C upstream_gene_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3640962 c.-573C>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640965 c.-570C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640974 c.432T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiA 3640979 p.Thr146Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640989 c.-546T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641187 c.-348T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641196 c.-339C>G upstream_gene_variant 0.7 clofazimine
pretomanid
delamanid
fbiB 3641226 c.-309G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641235 c.-300G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641239 c.-296T>C upstream_gene_variant 0.7 clofazimine
pretomanid
delamanid
fbiA 3641245 p.Glu235Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641250 c.-285A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641256 c.-279A>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641259 c.-276G>C upstream_gene_variant 0.58 clofazimine
pretomanid
delamanid
fbiA 3641260 p.Ile240Val missense_variant 0.58 clofazimine
pretomanid
delamanid
fbiB 3641265 c.-270C>G upstream_gene_variant 0.54 clofazimine
pretomanid
delamanid
fbiB 3641271 c.-264C>T upstream_gene_variant 0.47 clofazimine
pretomanid
delamanid
fbiB 3641274 c.-261G>C upstream_gene_variant 0.53 clofazimine
pretomanid
delamanid
fbiB 3641286 c.-249C>G upstream_gene_variant 0.52 clofazimine
pretomanid
delamanid
fbiA 3641288 p.Glu249Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641310 c.-225C>A upstream_gene_variant 0.53 clofazimine
pretomanid
delamanid
fbiA 3641314 p.Thr258Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641322 c.-213T>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641337 c.-198G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641349 c.-186G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641351 p.Ala270Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641355 c.-180T>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641376 c.-159G>C upstream_gene_variant 0.64 clofazimine
pretomanid
delamanid
fbiB 3641379 c.-156G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641380 p.Cys280Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641384 p.Ala281Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641388 c.-147C>T upstream_gene_variant 0.67 clofazimine
pretomanid
delamanid
fbiB 3641397 c.-138G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641418 p.Asp292Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641424 c.-111C>T upstream_gene_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3642635 p.Asp367Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642687 c.1153C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
alr 3840274 p.Val383Leu missense_variant 0.88 cycloserine
alr 3840275 c.1146T>G synonymous_variant 0.88 cycloserine
alr 3840293 c.1128T>G synonymous_variant 0.88 cycloserine
alr 3840296 c.1125G>C synonymous_variant 0.88 cycloserine
alr 3840302 c.1119G>A synonymous_variant 0.88 cycloserine
alr 3840308 c.1111_1113delCGGinsAC frameshift_variant&missense_variant 0.88 cycloserine
alr 3840312 p.Ile370Ser missense_variant 0.89 cycloserine
alr 3840320 c.1101G>T synonymous_variant 0.9 cycloserine
alr 3840328 c.1093T>C synonymous_variant 0.91 cycloserine
alr 3840329 c.1092T>C synonymous_variant 0.91 cycloserine
alr 3840353 c.1068T>C synonymous_variant 0.92 cycloserine
alr 3840356 p.Leu355Thr missense_variant 0.92 cycloserine
alr 3840360 p.Pro354Gln missense_variant 0.88 cycloserine
alr 3840362 c.1059G>A synonymous_variant 0.89 cycloserine
alr 3840380 c.1039_1041delATGinsGC frameshift_variant&missense_variant 1.0 cycloserine
alr 3840407 c.1014G>C synonymous_variant 0.96 cycloserine
alr 3840410 c.1011T>G synonymous_variant 1.0 cycloserine
alr 3840416 c.1003_1005delTGCinsCG frameshift_variant&missense_variant 1.0 cycloserine
alr 3840419 c.1002A>C synonymous_variant 1.0 cycloserine
alr 3840422 p.Arg333Lys missense_variant 1.0 cycloserine
alr 3840436 c.985C>T synonymous_variant 1.0 cycloserine
alr 3840443 c.978G>C synonymous_variant 1.0 cycloserine
alr 3840460 p.Ser321Ala missense_variant 0.95 cycloserine
alr 3840461 c.960G>A synonymous_variant 0.95 cycloserine
alr 3840467 c.954G>C synonymous_variant 1.0 cycloserine
alr 3840476 c.945A>C synonymous_variant 1.0 cycloserine
alr 3840482 c.939T>C synonymous_variant 1.0 cycloserine
alr 3840497 c.924G>A synonymous_variant 0.79 cycloserine
alr 3840503 c.918T>C synonymous_variant 1.0 cycloserine
alr 3840515 p.Pro302Gln missense_variant 1.0 cycloserine
alr 3840522 p.Ile300Thr missense_variant 1.0 cycloserine
alr 3840527 c.894A>C synonymous_variant 1.0 cycloserine
alr 3840536 c.885T>C synonymous_variant 1.0 cycloserine
alr 3840547 p.Gly292Ser missense_variant 1.0 cycloserine
alr 3840557 c.864T>C synonymous_variant 1.0 cycloserine
alr 3840560 c.861T>C synonymous_variant 1.0 cycloserine
alr 3840563 c.858G>A synonymous_variant 0.91 cycloserine
alr 3840566 c.855A>G synonymous_variant 1.0 cycloserine
alr 3840578 c.843T>G synonymous_variant 1.0 cycloserine
alr 3840583 p.Ala280Pro missense_variant 1.0 cycloserine
alr 3840590 c.831G>C synonymous_variant 0.9 cycloserine
alr 3840593 c.828C>G synonymous_variant 0.9 cycloserine
alr 3840599 c.822G>A synonymous_variant 0.9 cycloserine
alr 3840620 c.801T>C synonymous_variant 0.95 cycloserine
alr 3840658 p.Ile255Val missense_variant 1.0 cycloserine
alr 3840662 c.759G>C synonymous_variant 1.0 cycloserine
alr 3840682 p.Thr247Ala missense_variant 1.0 cycloserine
rpoA 3877482 c.1026C>G synonymous_variant 1.0 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 1.0 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.62 rifampicin
rpoA 3877509 c.999G>A synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877533 c.975C>G synonymous_variant 0.38 rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.6 rifampicin
rpoA 3877548 c.960C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3877553 p.Glu319Gln missense_variant 1.0 rifampicin
rpoA 3877554 c.954G>A synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 0.65 rifampicin
rpoA 3877578 c.930C>T synonymous_variant 0.64 rifampicin
rpoA 3877584 c.924C>G synonymous_variant 0.63 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877614 c.894G>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877629 c.879C>G synonymous_variant 0.37 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.4 rifampicin
rpoA 3877677 c.829_831delGCGinsTC frameshift_variant&missense_variant 0.36 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877689 c.819C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 1.0 rifampicin
rpoA 3877729 c.778_779delTCinsAG synonymous_variant 1.0 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 1.0 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877797 c.711G>A synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3877806 c.702C>T synonymous_variant 0.34 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.4 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877929 c.579C>T synonymous_variant 0.4 rifampicin
rpoA 3877959 c.549C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.64 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 1.0 rifampicin
rpoA 3877983 c.525C>T synonymous_variant 0.65 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 0.36 rifampicin
rpoA 3877995 c.513G>T synonymous_variant 0.6 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.62 rifampicin
rpoA 3878028 c.480G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878043 c.465G>C synonymous_variant 1.0 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 1.0 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878058 c.450G>A synonymous_variant 0.39 rifampicin
rpoA 3878067 c.441C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878076 c.432C>G synonymous_variant 0.53 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.45 rifampicin
rpoA 3878100 c.408C>G synonymous_variant 0.53 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.57 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>G synonymous_variant 0.54 rifampicin
rpoA 3878166 c.342C>G synonymous_variant 0.45 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.36 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 0.62 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.99 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878274 c.234G>C synonymous_variant 0.67 rifampicin
rpoA 3878284 p.Glu75Ala missense_variant 1.0 rifampicin
rpoA 3878286 c.222C>G synonymous_variant 1.0 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878309 p.Pro67Ala missense_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 0.83 rifampicin
rpoA 3878415 c.93C>G synonymous_variant 1.0 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 1.0 rifampicin
rpoA 3878433 c.75G>C synonymous_variant 1.0 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 1.0 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878451 c.57C>G synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 1.0 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 1.0 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 1.0 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 1.0 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 1.0 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 1.0 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878704 c.-197C>T upstream_gene_variant 0.5 rifampicin
rpoA 3878716 c.-209C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878719 c.-212G>A upstream_gene_variant 0.58 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.45 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.42 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878749 c.-242G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878755 c.-248G>A upstream_gene_variant 0.42 rifampicin
rpoA 3878758 c.-251G>C upstream_gene_variant 0.42 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.56 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878776 c.-269G>C upstream_gene_variant 0.58 rifampicin
rpoA 3878785 c.-278T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878837 c.-331_-330delAAinsTC upstream_gene_variant 1.0 rifampicin
rpoA 3878839 c.-332C>G upstream_gene_variant 0.64 rifampicin
rpoA 3878842 c.-335G>C upstream_gene_variant 0.64 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878917 c.-410G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>G upstream_gene_variant 0.7 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878950 c.-443C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878962 c.-455G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 1.0 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879040 c.-533G>C upstream_gene_variant 0.75 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 0.72 rifampicin
rpoA 3879079 c.-572A>C upstream_gene_variant 0.98 rifampicin
rpoA 3879085 c.-578C>T upstream_gene_variant 0.72 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.67 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879202 c.-695T>A upstream_gene_variant 0.36 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879223 c.-716G>C upstream_gene_variant 0.66 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 1.0 rifampicin
ddn 3986624 c.-220G>C upstream_gene_variant 0.46 delamanid
pretomanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.48 delamanid
pretomanid
ddn 3986637 c.-207C>T upstream_gene_variant 0.52 delamanid
pretomanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.52 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986651 c.-193G>A upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986655 c.-189_-187delACCinsTG upstream_gene_variant 0.44 delamanid
pretomanid
ddn 3986665 c.-179G>C upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986705 c.-139C>G upstream_gene_variant 1.0 delamanid
pretomanid
clpC1 4038212 c.2493T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038270 p.Pro812Ser missense_variant 0.71 pyrazinamide
clpC1 4038272 c.2433T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038275 c.2430A>G synonymous_variant 0.71 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038377 c.2328C>A synonymous_variant 0.62 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038428 c.2277G>C synonymous_variant 0.49 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038440 c.2265C>G synonymous_variant 0.48 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.44 pyrazinamide
clpC1 4038461 c.2242_2244delGCGinsTC frameshift_variant&missense_variant 0.51 pyrazinamide
clpC1 4038474 p.Ser744Ala missense_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.51 pyrazinamide
clpC1 4038488 c.2217C>G synonymous_variant 0.49 pyrazinamide
clpC1 4038506 c.2199G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.47 pyrazinamide
clpC1 4038519 p.Arg729Lys missense_variant 0.5 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 p.Arg724Lys missense_variant 1.0 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.42 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.44 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 1.0 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.36 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038674 c.2031C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038692 c.2013C>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.64 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.37 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.4 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.38 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.42 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.58 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.57 pyrazinamide
clpC1 4038821 c.1884G>A synonymous_variant 0.43 pyrazinamide
clpC1 4038851 c.1854G>A synonymous_variant 0.44 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038884 c.1821C>T synonymous_variant 0.45 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.59 pyrazinamide
clpC1 4038896 c.1809C>T synonymous_variant 0.41 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 0.57 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039046 c.1659C>A synonymous_variant 0.62 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039073 c.1632C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.63 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.64 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.37 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 0.39 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039268 c.1437C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039289 c.1416T>C synonymous_variant 0.44 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.44 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 0.59 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.62 pyrazinamide
clpC1 4039316 c.1389G>A synonymous_variant 0.38 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.37 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.63 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039388 c.1317C>A synonymous_variant 0.61 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>A synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039524 p.Phe394Tyr missense_variant 0.62 pyrazinamide
clpC1 4039526 c.1179G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039576 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.84 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.84 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>A synonymous_variant 0.29 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.69 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039844 c.861C>T synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.4 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039951 c.754C>T synonymous_variant 0.76 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039979 c.724_726delCTCinsTG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4039982 c.723G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 1.0 pyrazinamide
clpC1 4039997 c.708C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040048 c.657C>T synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.64 pyrazinamide
clpC1 4040108 c.597G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040129 c.576C>G synonymous_variant 0.67 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.48 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.79 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040219 c.486C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040222 c.483G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.72 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 0.69 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 0.75 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040309 c.396C>G synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4040315 c.390G>A synonymous_variant 0.56 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.53 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 0.44 pyrazinamide
clpC1 4040441 c.262_264delCTCinsTG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.47 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>A synonymous_variant 0.45 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040495 c.210C>G synonymous_variant 0.57 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040537 c.168G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.6 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.62 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040576 c.129C>T synonymous_variant 0.35 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040588 c.117T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.33 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.37 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.53 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 1.0 pyrazinamide
panD 4044051 c.231C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044054 c.228G>C synonymous_variant 1.0 pyrazinamide
panD 4044057 c.225C>A synonymous_variant 1.0 pyrazinamide
panD 4044063 c.219T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044066 c.216C>T synonymous_variant 0.62 pyrazinamide
panD 4044075 c.207T>C synonymous_variant 1.0 pyrazinamide
panD 4044081 c.201T>G synonymous_variant 1.0 pyrazinamide
panD 4044084 c.198T>C synonymous_variant 1.0 pyrazinamide
panD 4044090 c.192C>T synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
panD 4044096 c.186C>G synonymous_variant 0.68 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 1.0 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 1.0 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 1.0 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 1.0 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 1.0 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 0.67 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 1.0 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 1.0 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044210 c.72C>T synonymous_variant 0.77 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 1.0 pyrazinamide
panD 4044240 c.42G>C synonymous_variant 1.0 pyrazinamide
panD 4044258 c.24G>C synonymous_variant 0.77 pyrazinamide
panD 4044264 c.18G>C synonymous_variant 1.0 pyrazinamide
panD 4044629 c.-348G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044644 c.-363A>G upstream_gene_variant 0.81 pyrazinamide
panD 4044650 c.-369G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044656 c.-375G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044677 c.-396T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044682 c.-401C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044686 c.-405C>G upstream_gene_variant 0.75 pyrazinamide
panD 4044692 c.-413_-411delGCGinsAC upstream_gene_variant 1.0 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044704 c.-423G>A upstream_gene_variant 0.79 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044755 c.-474G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044758 c.-478_-477delGCinsAT upstream_gene_variant 1.0 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044872 c.-591C>A upstream_gene_variant 0.75 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044927 c.-646C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044929 c.-648G>C upstream_gene_variant 0.92 pyrazinamide
panD 4044935 c.-655_-654delAAinsTG upstream_gene_variant 0.93 pyrazinamide
panD 4044953 c.-673_-672delCGinsTT upstream_gene_variant 0.95 pyrazinamide
panD 4044977 c.-696T>C upstream_gene_variant 0.87 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.96 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.96 pyrazinamide
panD 4044998 c.-719_-717delATGinsCC upstream_gene_variant 0.7 pyrazinamide
panD 4045022 c.-742_-741delTCinsCG upstream_gene_variant 0.95 pyrazinamide
panD 4045025 c.-744C>G upstream_gene_variant 0.95 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.95 pyrazinamide
panD 4045031 c.-752_-750delTCGinsGC upstream_gene_variant 0.67 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.93 pyrazinamide
panD 4045055 c.-774T>C upstream_gene_variant 0.95 pyrazinamide
panD 4045063 c.-782T>C upstream_gene_variant 0.9 pyrazinamide
panD 4045064 c.-783G>C upstream_gene_variant 0.65 pyrazinamide
panD 4045073 c.-792C>G upstream_gene_variant 0.93 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 1.0 pyrazinamide
glpK 4138385 c.1371A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138415 c.1341G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138424 c.1332T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138427 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.36 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138451 c.1305T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138457 c.1299C>T synonymous_variant 0.71 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138464 p.Gly431Ala missense_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138471 p.Ile429Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138490 c.1266G>T synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138495 p.Gln421Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138496 c.1260G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 p.Glu413Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138550 c.1206C>T synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138556 c.1200G>C synonymous_variant 0.63 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138579 p.Leu393Val missense_variant 0.42 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138580 c.1176C>T synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138583 c.1173G>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138587 p.Asn390Ser missense_variant 0.53 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138607 c.1149G>C synonymous_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138616 c.1140G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>T synonymous_variant 0.7 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>T synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138682 c.1074C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138696 p.Pro354Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138702 p.Gln352Glu missense_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138706 c.1050C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138714 p.Ala348Ser missense_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138739 c.1017C>T synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138751 c.1005T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138781 c.975G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139207 c.549T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139215 c.541T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139228 c.528G>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139231 c.525A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139234 c.522C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139242 c.514T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139243 c.513A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139252 c.504C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139276 c.480T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139282 c.474T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139285 c.471A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139290 c.466C>T synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139306 c.450C>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139312 c.444T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139321 c.435T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139324 c.432A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139330 c.426G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139540 p.Ile72Met missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139545 c.211T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139554 p.Ala68Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139558 c.198C>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139576 c.180G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139600 c.156G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139615 c.141G>A synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139621 c.135G>A synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid
glpK 4139642 c.114G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139653 p.His35Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139654 c.102C>T synonymous_variant 0.82 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139675 c.81C>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139687 c.69C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139707 c.-846_48del conservative_inframe_deletion 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4238969 c.-894A>G upstream_gene_variant 1.0 ethambutol
embC 4238972 c.-891C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4238975 c.-888A>C upstream_gene_variant 1.0 ethambutol
embC 4238986 c.-877_-876delCAinsTG upstream_gene_variant 1.0 ethambutol
embC 4238999 c.-864C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239020 c.-843G>C upstream_gene_variant 1.0 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239042 c.-821_-819delACGinsGC upstream_gene_variant 1.0 ethambutol
embC 4239057 c.-806A>C upstream_gene_variant 1.0 ethambutol
embC 4239065 c.-798G>C upstream_gene_variant 1.0 ethambutol
embC 4239068 c.-795A>T upstream_gene_variant 1.0 ethambutol
embC 4239076 c.-787C>T upstream_gene_variant 1.0 ethambutol
embC 4239079 c.-784_-783delCAinsGG upstream_gene_variant 1.0 ethambutol
embC 4239083 c.-780C>G upstream_gene_variant 1.0 ethambutol
embC 4239094 c.-769_-768delCCinsGG upstream_gene_variant 1.0 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 1.0 ethambutol
embC 4239141 c.-722_-720delGCCinsAG upstream_gene_variant 1.0 ethambutol
embC 4239146 c.-717A>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 1.0 ethambutol
embC 4240183 c.321A>G synonymous_variant 1.0 ethambutol
embC 4240198 c.336G>A synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embC 4240201 c.339G>C synonymous_variant 1.0 ethambutol
embC 4240204 c.342T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240216 c.354T>C synonymous_variant 1.0 ethambutol
embC 4240228 c.366G>C synonymous_variant 0.83 ethambutol
embC 4240229 c.367_369delCTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embC 4240237 c.375G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240247 p.Asp129Tyr missense_variant 1.0 ethambutol
embC 4240258 c.396T>G synonymous_variant 1.0 ethambutol
embC 4240267 c.405T>C synonymous_variant 1.0 ethambutol
embC 4240270 c.408T>C synonymous_variant 1.0 ethambutol
embC 4240274 p.Pro138Ala missense_variant 1.0 ethambutol
embC 4240277 p.Leu139Val missense_variant 1.0 ethambutol
embC 4240297 c.435T>C synonymous_variant 1.0 ethambutol
embC 4240298 p.Gln146Glu missense_variant 0.9 ethambutol
embC 4240307 p.Gly149Ser missense_variant 1.0 ethambutol Uncertain significance
embC 4240313 p.Thr151Ala missense_variant 1.0 ethambutol
embC 4240318 c.456T>C synonymous_variant 0.85 ethambutol
embC 4240330 c.468A>G synonymous_variant 1.0 ethambutol
embC 4240348 c.486T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240351 c.489G>C synonymous_variant 1.0 ethambutol
embC 4240355 p.Ala165Thr missense_variant 1.0 ethambutol Uncertain significance
embC 4240372 c.510A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240375 c.513G>C synonymous_variant 0.59 ethambutol
embC 4240376 p.Val172Thr missense_variant 1.0 ethambutol
embC 4240384 c.522A>G synonymous_variant 0.61 ethambutol
embC 4240390 c.528T>C synonymous_variant 1.0 ethambutol
embC 4240391 c.529_531delGCTinsTC frameshift_variant&missense_variant 0.39 ethambutol
embC 4240402 c.540C>G synonymous_variant 0.59 ethambutol
embC 4240406 p.Ala182Ser missense_variant 1.0 ethambutol
embC 4240412 c.550C>T synonymous_variant 0.38 ethambutol
embC 4240420 c.558T>C synonymous_variant 1.0 ethambutol
embC 4240424 p.Arg188Lys missense_variant 1.0 ethambutol
embC 4240435 c.573C>T synonymous_variant 0.39 ethambutol
embC 4240444 c.582C>G synonymous_variant 1.0 ethambutol
embC 4240447 c.585G>C synonymous_variant 1.0 ethambutol
embC 4240472 c.610C>T synonymous_variant 0.67 ethambutol
embC 4240483 c.621G>C synonymous_variant 0.59 ethambutol
embC 4240489 c.627A>G synonymous_variant 1.0 ethambutol
embC 4240642 c.780G>C synonymous_variant 1.0 ethambutol
embC 4240645 c.783G>A synonymous_variant 1.0 ethambutol
embC 4240654 c.792C>G synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embC 4240655 p.Ala265Ser missense_variant 1.0 ethambutol
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4240678 c.816T>C synonymous_variant 1.0 ethambutol
embC 4240685 p.Thr275Ala missense_variant 1.0 ethambutol
embC 4240693 c.831T>G synonymous_variant 1.0 ethambutol
embC 4240706 p.Val282Thr missense_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>G synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240859 c.997C>T synonymous_variant 0.4 ethambutol
embC 4240867 c.1005T>C synonymous_variant 1.0 ethambutol
embC 4240870 c.1008T>C synonymous_variant 1.0 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.54 ethambutol
embC 4240880 p.Ala340Thr missense_variant 1.0 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 1.0 ethambutol
embC 4240897 c.1035C>G synonymous_variant 1.0 ethambutol Not assoc w R
embC 4240900 c.1038A>G synonymous_variant 1.0 ethambutol
embC 4240909 c.1047G>C synonymous_variant 0.42 ethambutol
embC 4240912 c.1050G>C synonymous_variant 1.0 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.52 ethambutol
embC 4240936 c.1074A>G synonymous_variant 1.0 ethambutol
embC 4240945 c.1083T>G synonymous_variant 1.0 ethambutol
embC 4240948 c.1086G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240951 c.1089C>G synonymous_variant 0.59 ethambutol
embC 4240954 p.Ile364Met missense_variant 1.0 ethambutol
embC 4240957 c.1095C>G synonymous_variant 1.0 ethambutol
embC 4240979 p.Thr373Gln missense_variant 1.0 ethambutol
embC 4240987 c.1125G>C synonymous_variant 0.9 ethambutol
embC 4241002 c.1140G>C synonymous_variant 1.0 ethambutol
embC 4241008 c.1146G>C synonymous_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 1.0 ethambutol
embC 4241023 c.1161T>C synonymous_variant 1.0 ethambutol
embC 4241026 c.1164C>G synonymous_variant 1.0 ethambutol
embC 4241035 c.1173G>A synonymous_variant 0.39 ethambutol
embC 4241038 c.1176G>C synonymous_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241071 c.1209C>G synonymous_variant 1.0 ethambutol
embC 4241074 c.1212G>C synonymous_variant 0.54 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.54 ethambutol
embC 4241104 c.1242G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241137 c.1275G>C synonymous_variant 0.42 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241141 p.Ile427Val missense_variant 1.0 ethambutol Uncertain significance
embC 4241154 p.Ile431Thr missense_variant 0.48 ethambutol
embC 4241158 c.1296T>A synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.46 ethambutol
embC 4241194 c.1332C>G synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>G synonymous_variant 0.44 ethambutol
embC 4241206 c.1344G>A synonymous_variant 0.44 ethambutol Not assoc w R - Interim
embC 4241219 p.Ile453Val missense_variant 0.6 ethambutol
embC 4241230 c.1368A>G synonymous_variant 1.0 ethambutol
embC 4241233 c.1371G>C synonymous_variant 0.4 ethambutol
embC 4241288 c.1426_1428delATCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embC 4241312 c.1450_1452delGCGinsAC frameshift_variant&missense_variant 0.71 ethambutol
embC 4241319 p.Pro486Leu missense_variant 1.0 ethambutol
embC 4241326 c.1464T>C synonymous_variant 1.0 ethambutol
embA 4244543 c.1311C>G synonymous_variant 1.0 ethambutol
embA 4244556 p.Arg442Val missense_variant 1.0 ethambutol
embA 4244561 c.1329C>T synonymous_variant 1.0 ethambutol
embA 4244564 c.1332G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244575 p.Ala448Val missense_variant 1.0 ethambutol
embA 4244582 c.1350T>C synonymous_variant 1.0 ethambutol
embA 4244608 c.1377_1379delGGC disruptive_inframe_deletion 1.0 ethambutol
embA 4244618 c.1386G>T synonymous_variant 0.83 ethambutol
embA 4244619 c.1387_1388insCCC disruptive_inframe_insertion 1.0 ethambutol
embA 4244636 c.1404G>C synonymous_variant 1.0 ethambutol
embA 4244645 c.1413T>C synonymous_variant 1.0 ethambutol
embA 4244648 c.1416G>C synonymous_variant 1.0 ethambutol
embA 4244649 p.Asp473Ser missense_variant 1.0 ethambutol
embA 4244669 c.1437G>C synonymous_variant 1.0 ethambutol
embA 4244675 c.1443A>G synonymous_variant 1.0 ethambutol
embA 4244678 c.1446G>A synonymous_variant 0.81 ethambutol Not assoc w R - Interim
embA 4244681 c.1449A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244690 c.1458G>A synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embA 4244708 c.1476C>G synonymous_variant 1.0 ethambutol
embA 4244714 c.1482C>G synonymous_variant 1.0 ethambutol
embA 4244735 c.1503C>G synonymous_variant 0.87 ethambutol
embA 4244747 c.1515T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244750 c.1518C>G synonymous_variant 1.0 ethambutol
embA 4244756 c.1524G>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embA 4244762 c.1530C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embA 4244763 p.Val511Pro missense_variant 1.0 ethambutol
embA 4244768 p.Glu512Asp missense_variant 1.0 ethambutol
embA 4244778 c.1546_1548delTCCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244783 c.1551C>G synonymous_variant 0.87 ethambutol
embA 4244786 c.1554G>C synonymous_variant 1.0 ethambutol
embA 4244802 c.1570T>C synonymous_variant 1.0 ethambutol
embA 4244810 p.Phe526Leu missense_variant 1.0 ethambutol
embA 4244823 p.Val531Met missense_variant 1.0 ethambutol
embA 4244829 p.Phe533Val missense_variant 1.0 ethambutol
embA 4244850 p.Arg540Gly missense_variant 0.81 ethambutol
embA 4244856 c.1624_1626delGCGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244861 c.1629G>T synonymous_variant 0.69 ethambutol
embA 4244869 p.Ser546Thr missense_variant 0.64 ethambutol
embA 4244873 c.1641C>G synonymous_variant 0.62 ethambutol
embA 4244878 p.Ala549Val missense_variant 0.62 ethambutol
embA 4244885 c.1653A>G synonymous_variant 1.0 ethambutol
embA 4244897 c.1665T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244909 c.1677C>T synonymous_variant 0.69 ethambutol
embA 4244921 c.1689C>G synonymous_variant 1.0 ethambutol
embA 4244923 p.Thr564Asn missense_variant 0.73 ethambutol
embA 4244936 c.1704C>G synonymous_variant 1.0 ethambutol
embA 4244960 c.1728A>G synonymous_variant 1.0 ethambutol
embA 4244987 c.1755T>C synonymous_variant 1.0 ethambutol
embA 4245003 c.1771_1773delACCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245008 c.1776T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245020 c.1788T>C synonymous_variant 1.0 ethambutol
embA 4245023 c.1791A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245026 c.1794T>C synonymous_variant 1.0 ethambutol
embA 4245029 c.1797T>C synonymous_variant 1.0 ethambutol
embA 4245032 c.1800A>C synonymous_variant 1.0 ethambutol
embA 4245041 c.1809C>G synonymous_variant 1.0 ethambutol
embA 4245044 c.1812G>C synonymous_variant 0.58 ethambutol
embA 4245060 c.1828T>C synonymous_variant 1.0 ethambutol
embA 4245065 c.1833G>C synonymous_variant 1.0 ethambutol
embA 4245083 c.1851A>C synonymous_variant 1.0 ethambutol
embA 4245089 c.1857G>C synonymous_variant 1.0 ethambutol
embA 4245093 p.Ile621Val missense_variant 1.0 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245137 c.1905T>C synonymous_variant 1.0 ethambutol
embA 4245145 p.Gln638Pro missense_variant 0.38 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.41 ethambutol
embA 4245164 c.1932C>T synonymous_variant 0.64 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.58 ethambutol
embA 4245183 c.1951C>T synonymous_variant 1.0 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.58 ethambutol
embA 4245200 c.1968C>G synonymous_variant 1.0 ethambutol
embA 4245206 c.1974A>G synonymous_variant 0.53 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245212 c.1980G>C synonymous_variant 0.55 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245217 p.Ala662Gly missense_variant 0.42 ethambutol
embA 4245222 c.1990_1992delTATinsCG frameshift_variant&missense_variant 0.58 ethambutol Uncertain significance
embA 4245227 c.1995C>T synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embA 4245248 c.2016G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245257 c.2025A>G synonymous_variant 1.0 ethambutol
embA 4245263 c.2031A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245268 p.Asn679Ser missense_variant 1.0 ethambutol
embA 4245282 c.2050_2052delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245285 c.2053T>C synonymous_variant 1.0 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 1.0 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embB 4245767 c.-747G>A upstream_gene_variant 0.62 ethambutol
embA 4245771 p.Asn847Ser missense_variant 1.0 ethambutol Uncertain significance
embB 4245779 c.-735C>G upstream_gene_variant 0.6 ethambutol
embA 4245785 c.2553G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245788 c.-726C>G upstream_gene_variant 1.0 ethambutol
embA 4245795 c.2563_2565delGCCinsTG frameshift_variant&missense_variant 0.53 ethambutol Uncertain significance
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245820 p.Ser863Thr missense_variant 1.0 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 0.5 ethambutol
embB 4245830 c.-684G>A upstream_gene_variant 0.5 ethambutol
embB 4245848 c.-666C>G upstream_gene_variant 0.54 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 1.0 ethambutol
embB 4245869 c.-645C>G upstream_gene_variant 0.55 ethambutol
embB 4246244 c.-270G>A upstream_gene_variant 1.0 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 1.0 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 1.0 ethambutol
embA 4246290 p.Leu1020Gly missense_variant 1.0 ethambutol
embA 4246296 p.Gln1022Glu missense_variant 1.0 ethambutol
embA 4246299 p.Ser1023Ala missense_variant 1.0 ethambutol
embA 4246302 p.Ser1024Gly missense_variant 1.0 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 1.0 ethambutol
embA 4246308 p.Thr1026Asp missense_variant 1.0 ethambutol
embA 4246326 p.Phe1032Val missense_variant 1.0 ethambutol
embB 4246331 c.-183C>G upstream_gene_variant 1.0 ethambutol
embB 4246337 c.-177G>C upstream_gene_variant 1.0 ethambutol
embA 4246338 p.Leu1036Met missense_variant 1.0 ethambutol
embB 4246349 c.-165C>T upstream_gene_variant 1.0 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4246370 c.-144G>T upstream_gene_variant 1.0 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 1.0 ethambutol
embB 4246400 c.-114G>C upstream_gene_variant 1.0 ethambutol
embB 4246403 c.-111G>C upstream_gene_variant 1.0 ethambutol
embB 4247380 c.867C>G synonymous_variant 1.0 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.57 ethambutol
embB 4247389 c.876C>G synonymous_variant 1.0 ethambutol
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247404 c.891G>C synonymous_variant 1.0 ethambutol
embB 4247407 c.894G>C synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>C synonymous_variant 1.0 ethambutol
embB 4247452 c.939C>G synonymous_variant 1.0 ethambutol
embB 4247455 c.942C>T synonymous_variant 1.0 ethambutol
embB 4247464 c.951C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247494 c.981G>A synonymous_variant 0.65 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247550 p.Ala346Gly missense_variant 1.0 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>A synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>C synonymous_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247591 c.1078_1080delGTGinsAC frameshift_variant&missense_variant 0.32 ethambutol
embB 4247614 c.1101T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247632 c.1119C>G synonymous_variant 1.0 ethambutol
embB 4247645 p.Glu378Thr missense_variant 1.0 ethambutol
embB 4247648 p.Ala379Ser missense_variant 1.0 ethambutol
embB 4247656 c.1143A>G synonymous_variant 1.0 ethambutol
embB 4247657 p.Pro382Ala missense_variant 1.0 ethambutol
embB 4247674 c.1161G>C synonymous_variant 0.85 ethambutol
embB 4247678 p.Met389Leu missense_variant 1.0 ethambutol
embB 4247684 c.1171T>C synonymous_variant 1.0 ethambutol
embB 4247689 c.1176G>C synonymous_variant 1.0 ethambutol
embB 4247695 c.1182G>C synonymous_variant 0.89 ethambutol
embB 4247716 c.1203C>T synonymous_variant 1.0 ethambutol
embB 4247722 c.1209G>C synonymous_variant 1.0 ethambutol
embB 4247725 c.1212G>C synonymous_variant 1.0 ethambutol
embB 4247729 p.Gly406Pro missense_variant 1.0 ethambutol
embB 4247743 c.1230C>G synonymous_variant 1.0 ethambutol
embB 4247746 c.1233C>T synonymous_variant 1.0 ethambutol
embB 4247753 p.Val414Ile missense_variant 0.85 ethambutol Uncertain significance
embB 4247761 c.1248T>C synonymous_variant 1.0 ethambutol
embB 4247836 c.1323A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247837 c.1324C>T synonymous_variant 0.8 ethambutol
embB 4247842 c.1329T>G synonymous_variant 1.0 ethambutol
embB 4247848 c.1335G>A synonymous_variant 1.0 ethambutol
embB 4247854 c.1341C>T synonymous_variant 1.0 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.9 ethambutol
embB 4247884 c.1371C>G synonymous_variant 0.9 ethambutol
embB 4247890 c.1377C>G synonymous_variant 1.0 ethambutol
embB 4247893 c.1380C>G synonymous_variant 1.0 ethambutol
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247905 c.1392G>A synonymous_variant 1.0 ethambutol
embB 4247911 p.Leu466Phe missense_variant 1.0 ethambutol
embB 4247916 p.Arg468His missense_variant 1.0 ethambutol Uncertain significance
embB 4247920 c.1407T>G synonymous_variant 1.0 ethambutol
embB 4247927 c.1414C>T synonymous_variant 1.0 ethambutol
embB 4247938 c.1425G>T synonymous_variant 1.0 ethambutol
embB 4247940 p.Leu476Trp missense_variant 1.0 ethambutol
embB 4247945 c.1432T>C synonymous_variant 1.0 ethambutol
embB 4247951 c.1438_1440delTCGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247957 p.Met482Leu missense_variant 1.0 ethambutol
embB 4247971 c.1458C>A synonymous_variant 1.0 ethambutol
embB 4247972 c.1459_1461delACCinsTG frameshift_variant&missense_variant 1.0 ethambutol
embB 4247983 c.1470G>C synonymous_variant 1.0 ethambutol
embB 4247992 c.1479G>C synonymous_variant 1.0 ethambutol
embB 4248008 c.1495C>T synonymous_variant 1.0 ethambutol
embB 4248025 c.1512A>G synonymous_variant 1.0 ethambutol
embB 4248035 p.Val508Ile missense_variant 1.0 ethambutol
embB 4248041 p.Ala510Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 1.0 ethambutol
embB 4248055 c.1542G>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.81 ethambutol
embB 4248088 c.1575C>T synonymous_variant 0.8 ethambutol
embB 4248112 c.1599C>T synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248133 c.1620C>A synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 1.0 ethambutol
embB 4248178 c.1665C>T synonymous_variant 0.68 ethambutol
embB 4248190 c.1677G>C synonymous_variant 0.99 ethambutol Not assoc w R - Interim
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.99 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.99 ethambutol Not assoc w R - Interim
embB 4248226 c.1713G>A synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embB 4248232 c.1719G>T synonymous_variant 0.98 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.97 ethambutol
embB 4248280 c.1767C>G synonymous_variant 0.97 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.93 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.93 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.95 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.94 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.93 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.9 ethambutol
embB 4248360 p.Pro616His missense_variant 0.9 ethambutol
embB 4248362 p.Ser617Glu missense_variant 0.9 ethambutol
embB 4248368 c.1855C>T synonymous_variant 0.62 ethambutol
embB 4249321 c.2808A>G synonymous_variant 1.0 ethambutol
embB 4249322 c.2809_2811delGCAinsTT frameshift_variant&missense_variant 1.0 ethambutol
embB 4249325 c.2812_2814delAAGinsCA frameshift_variant&missense_variant 1.0 ethambutol
embB 4249330 p.Met939Ile missense_variant 0.87 ethambutol Uncertain significance
embB 4249334 p.Ala941Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4249339 c.2826T>C synonymous_variant 1.0 ethambutol
embB 4249342 c.2829C>G synonymous_variant 0.89 ethambutol
embB 4249348 c.2835G>C synonymous_variant 1.0 ethambutol
embB 4249355 p.Val948Leu missense_variant 1.0 ethambutol
embB 4249369 c.2856T>C synonymous_variant 1.0 ethambutol
embB 4249372 c.2859G>C synonymous_variant 0.91 ethambutol
embB 4249387 p.Glu958Asp missense_variant 1.0 ethambutol
embB 4249390 c.2877C>T synonymous_variant 0.93 ethambutol
embB 4249394 p.Ile961Leu missense_variant 1.0 ethambutol
embB 4249417 c.2904A>G synonymous_variant 1.0 ethambutol
embB 4249423 p.Asp970Glu missense_variant 1.0 ethambutol Uncertain significance
embB 4249432 c.2919A>C synonymous_variant 1.0 ethambutol
embB 4249433 p.Leu974Val missense_variant 1.0 ethambutol Uncertain significance
embB 4249444 c.2931T>C synonymous_variant 1.0 ethambutol
embB 4249445 c.2932_2934delGTGinsAC frameshift_variant&missense_variant 0.94 ethambutol
embB 4249450 c.2937C>G synonymous_variant 0.88 ethambutol
embB 4249454 c.2941_2943delACGinsTT frameshift_variant&missense_variant 0.88 ethambutol
embB 4249466 c.2953C>T synonymous_variant 0.79 ethambutol
embB 4249469 p.Leu986Met missense_variant 1.0 ethambutol
embB 4249483 c.2970C>G synonymous_variant 0.67 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249487 c.2974T>C synonymous_variant 1.0 ethambutol
embB 4249507 p.Gln998His missense_variant 1.0 ethambutol
embB 4249520 p.Ala1003Phe missense_variant 0.5 ethambutol
embB 4249523 c.3010_3012delAATinsGC frameshift_variant&missense_variant 0.6 ethambutol
aftB 4267550 c.1287C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267556 c.1281G>C synonymous_variant 1.0 ethambutol
aftB 4267589 c.1248G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267592 c.1245C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268099 c.738G>C synonymous_variant 1.0 ethambutol
aftB 4268102 c.735C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268123 c.712_714delAGTinsGC frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
aftB 4268126 c.711G>C synonymous_variant 1.0 ethambutol
aftB 4268129 c.708T>G synonymous_variant 1.0 ethambutol
aftB 4268134 c.703C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268138 c.699A>G synonymous_variant 1.0 ethambutol
aftB 4268144 c.693T>C synonymous_variant 1.0 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 1.0 ethambutol
aftB 4268171 c.666G>C synonymous_variant 1.0 ethambutol
aftB 4268175 c.658_661delTTGC frameshift_variant 1.0 ethambutol Uncertain significance
aftB 4268182 c.654_655insGCGC frameshift_variant 1.0 ethambutol Uncertain significance
aftB 4268194 p.Leu215Val missense_variant 1.0 ethambutol
aftB 4268207 c.630C>G synonymous_variant 1.0 ethambutol
aftB 4268213 c.624T>G synonymous_variant 1.0 ethambutol
aftB 4268219 c.618C>G synonymous_variant 1.0 ethambutol
aftB 4268228 c.609C>G synonymous_variant 1.0 ethambutol
aftB 4268233 p.Ile202Val missense_variant 1.0 ethambutol Uncertain significance
aftB 4268236 c.601T>C synonymous_variant 1.0 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 1.0 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 1.0 ethambutol
aftB 4269006 c.-170T>C upstream_gene_variant 1.0 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269015 c.819G>A synonymous_variant 0.73 ethambutol Not assoc w R - Interim
aftB 4269018 c.-182G>T upstream_gene_variant 1.0 ethambutol
aftB 4269027 c.-191C>G upstream_gene_variant 1.0 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 1.0 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.77 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.78 ethambutol
ubiA 4269066 c.768C>T synonymous_variant 0.78 ethambutol Not assoc w R - Interim
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 0.82 ethambutol
ubiA 4269091 p.Phe248Tyr missense_variant 1.0 ethambutol
aftB 4269132 c.-296G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269141 c.691_693delTTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269201 c.-365A>G upstream_gene_variant 1.0 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 1.0 ethambutol
ubiA 4269243 p.His197Gln missense_variant 1.0 ethambutol