TB-Profiler result

Run: SRR3742657
Summary

Run ID: SRR3742657

Sample name:

Date: 2024-04-16T03:40:34.793117

Number of reads: 3298004

Percentage reads mapped: 40.25

Median coverage: 75.0

Strain: La3;M.canetti;lineage2.2.1

Spoligotype:

Drug-resistance: Pre-XDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.95
lineage6.2.2 West-Africa 2 RD702 0.05
La1.2.BCG M.bovis None 0.25
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 0.92
lineage2.2 East-Asian (Beijing) RD105;RD207 0.98
lineage6.2.3 West-Africa 2 RD702 0.19
La1.7.1 M.bovis None 0.08
La3 M.orygis None 0.23
M.canetti M.canetti None 0.06
lineage6.2.1 West-Africa 2 RD702 0.09
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Asp435Val Assoc w R
isoniazid inhA c.-777C>T Assoc w R Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
katG c.-2237_*6541del Assoc w R High-level resistance
ahpC c.-81C>T Uncertain significance Mutation from literature
ethambutol embA c.-16C>T Uncertain significance Mutation from literature
embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide pncA p.Val180Gly Assoc w R
panD p.Val138Ala Mutation from literature
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
n.514A>C Assoc w R
fluoroquinolones
moxifloxacin gyrA p.Ala90Val Assoc w R Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
p.Ser91Pro Assoc w R Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
ofloxacin
levofloxacin gyrA p.Ala90Val Assoc w R
p.Ser91Pro Assoc w R
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>T Assoc w R - Interim
capreomycin rrs n.1402C>T Assoc w R
tlyA c.319_321delCACinsGA Assoc w R
c.376_378delCCTinsGG Assoc w R
kanamycin rrs n.1402C>T Assoc w R - Interim
cycloserine
ethionamide inhA c.-777C>T Assoc w R Alias fabG1_c.-15C>T
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1024_1026delGAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.358_360delCAGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrA 7570 p.Ala90Val missense_variant 0.71 levofloxacin Assoc w R
moxifloxacin Assoc w R Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
gyrA 7572 p.Ser91Pro missense_variant 0.71 levofloxacin Assoc w R
moxifloxacin Assoc w R Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 0.41 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.34 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 0.56 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761110 p.Asp435Val missense_variant 0.19 rifampicin Assoc w R
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.51 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303954 c.1024_1026delGAAinsCG frameshift_variant&missense_variant 0.4 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance Mutation from literature
rrs 1472359 n.514A>C non_coding_transcript_exon_variant 0.26 streptomycin Assoc w R
rrs 1473247 n.1402C>T non_coding_transcript_exon_variant 0.32 capreomycin Assoc w R
amikacin Assoc w R - Interim
kanamycin Assoc w R - Interim
inhA 1673425 c.-777C>T upstream_gene_variant 1.0 ethionamide Assoc w R Alias fabG1_c.-15C>T
isoniazid Assoc w R Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
tlyA 1918258 c.319_321delCACinsGA frameshift_variant&missense_variant 0.26 capreomycin Assoc w R
tlyA 1918315 c.376_378delCCTinsGG frameshift_variant&missense_variant 0.24 capreomycin Assoc w R
katG 2147347 c.-2237_*6541del transcript_ablation 0.99 isoniazid Assoc w R High-level resistance
pncA 2288703 p.Val180Gly missense_variant 1.0 pyrazinamide Assoc w R
ahpC 2726112 c.-81C>T upstream_gene_variant 1.0 isoniazid Uncertain significance Mutation from literature
fbiA 3640900 c.358_360delCAGinsAC frameshift_variant&missense_variant 0.48 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
panD 4043869 p.Val138Ala missense_variant 0.38 pyrazinamide Mutation from literature
embA 4243217 c.-16C>T upstream_gene_variant 0.9 ethambutol Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.56 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.3 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.37 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.42 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 0.36 isoniazid
dnaA 42 c.42C>T synonymous_variant 0.28 isoniazid
dnaA 51 c.51C>T synonymous_variant 0.19 isoniazid
dnaA 195 c.195G>T synonymous_variant 0.2 isoniazid Not assoc w R - Interim
dnaA 207 c.207T>C synonymous_variant 0.22 isoniazid
dnaA 210 c.210C>G synonymous_variant 0.22 isoniazid
dnaA 219 c.219A>G synonymous_variant 0.25 isoniazid
dnaA 225 c.225G>A synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 228 c.228C>G synonymous_variant 0.25 isoniazid
dnaA 510 c.510T>C synonymous_variant 0.3 isoniazid
dnaA 519 c.519C>G synonymous_variant 0.34 isoniazid Not assoc w R
dnaA 522 c.522T>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 0.37 isoniazid
dnaA 534 c.534T>C synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 558 c.558G>C synonymous_variant 0.54 isoniazid
dnaA 561 c.561C>T synonymous_variant 0.55 isoniazid
dnaA 567 c.567C>G synonymous_variant 0.58 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.59 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.58 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 0.58 isoniazid
dnaA 588 c.588A>C synonymous_variant 0.58 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.59 isoniazid
dnaA 600 c.600T>G synonymous_variant 0.6 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.57 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 649 c.649C>T synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.41 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.32 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.27 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>C synonymous_variant 0.24 isoniazid
dnaA 682 c.682T>C synonymous_variant 0.25 isoniazid
dnaA 693 c.693A>G synonymous_variant 0.38 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.36 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.38 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.4 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.39 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.37 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.37 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.39 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.42 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.4 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.33 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.29 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.22 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.18 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.21 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.3 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.3 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.34 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.39 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.4 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.42 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.44 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.51 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.5 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.47 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.44 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.42 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.4 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.45 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.45 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.4 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.39 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 0.41 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.42 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.58 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.49 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.48 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.47 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.46 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.44 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.42 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.43 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.33 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.31 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.27 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.25 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.32 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.39 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.41 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.5 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.48 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.47 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.49 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.49 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.51 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.53 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.51 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.48 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.44 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.42 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.37 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.35 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.21 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.35 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.37 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.4 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.4 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.41 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.42 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.46 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.49 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.48 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.51 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.56 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.5 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.48 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.4 isoniazid
dnaA 1485 c.1485A>G synonymous_variant 0.33 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.35 isoniazid
dnaA 1497 c.1497T>C synonymous_variant 0.31 isoniazid
dnaA 1506 c.1506T>G synonymous_variant 0.28 isoniazid
gyrB 5396 p.Ala53Ser missense_variant 0.18 levofloxacin
moxifloxacin
gyrB 5782 c.543A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrB 5788 c.549G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrB 5791 c.552A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrB 5803 c.564A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 5806 c.567C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 5809 c.570C>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrB 5812 c.573C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 5824 c.585A>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrB 5827 c.588G>A synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrB 5849 c.610C>T synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 5863 c.624G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrB 5880 p.Thr214Ser missense_variant 0.28 levofloxacin
moxifloxacin
gyrB 5882 c.643_645delCAAinsAC frameshift_variant&missense_variant 0.27 levofloxacin Uncertain significance
moxifloxacin
gyrB 5887 p.Asp216Glu missense_variant 0.26 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 5905 c.666G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.39 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.4 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrB 6670 c.1431G>A synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.62 levofloxacin Uncertain significance
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.5 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.45 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7015 c.-287G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrB 7124 c.1885_1887delTCGinsAC frameshift_variant&missense_variant 0.25 levofloxacin Uncertain significance
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7246 c.2007T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrB 7256 c.2017_2019delCTGinsTA frameshift_variant&stop_gained 0.19 levofloxacin Uncertain significance
moxifloxacin
gyrA 7307 c.6A>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7317 c.16T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 7324 c.23_24insAGG disruptive_inframe_insertion 0.27 levofloxacin
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 7347 c.46_48delGAAinsCG frameshift_variant&missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7712 p.Leu137Phe missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.3 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7775 c.474C>A synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7823 c.522G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7853 c.552C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8096 c.795T>A synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.56 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.52 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.56 levofloxacin
moxifloxacin
gyrA 8387 c.1086C>T synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>G synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>A synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318_1320delTTGinsCA frameshift_variant&missense_variant 0.54 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Arg missense_variant 0.38 levofloxacin Uncertain significance
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 8780 p.Asp493Glu missense_variant 0.28 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>G synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8837 c.1536C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.41 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9032 c.1731T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9056 c.1755C>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.61 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.68 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9284 c.1983T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9611 p.Asp770Glu missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 0.36 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9638 c.2337C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9641 c.2340C>A synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9665 c.2364A>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9666 p.Arg789Gly missense_variant 0.53 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9674 c.2373T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9708 c.2407T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9716 c.2415T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9727 p.Gly809Glu missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 9729 p.Asp810Asn missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9755 c.2454C>T synonymous_variant 0.31 levofloxacin
moxifloxacin
Rv0010c 13291 p.Asp90Asn missense_variant 0.2 isoniazid
Rv0010c 13320 p.Arg80Leu missense_variant 0.2 isoniazid
Rv0010c 13349 p.Ile70Met missense_variant 0.21 isoniazid
Rv0010c 13879 c.-321T>C upstream_gene_variant 0.22 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.3 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.31 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.33 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.36 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.35 isoniazid
fgd1 490782 c.-1G>C upstream_gene_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.48 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 0.63 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fgd1 490977 c.195C>G synonymous_variant 0.39 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Thr missense_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491001 c.219G>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.34 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 491130 c.348C>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.49 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 491173 c.391C>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.59 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.51 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491337 c.555C>G synonymous_variant 0.32 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491340 c.558C>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.34 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fgd1 491535 c.753G>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.63 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>A synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
mshA 575011 c.-337G>A upstream_gene_variant 0.21 ethionamide
isoniazid
mshA 575018 c.-330C>G upstream_gene_variant 0.29 ethionamide
isoniazid
mshA 575022 c.-326C>T upstream_gene_variant 0.32 ethionamide
isoniazid
mshA 575030 c.-318T>C upstream_gene_variant 0.32 ethionamide
isoniazid
mshA 575034 c.-314_-312delTTAinsAG upstream_gene_variant 0.33 ethionamide
isoniazid
mshA 575042 c.-306T>C upstream_gene_variant 0.32 ethionamide
isoniazid
mshA 575052 c.-296G>C upstream_gene_variant 0.35 ethionamide
isoniazid
mshA 575057 c.-291G>C upstream_gene_variant 0.36 ethionamide
isoniazid
mshA 575060 c.-288G>C upstream_gene_variant 0.36 ethionamide
isoniazid
mshA 575063 c.-285T>C upstream_gene_variant 0.36 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 0.43 ethionamide
isoniazid Uncertain significance
mshA 575084 c.-264T>C upstream_gene_variant 0.53 ethionamide
isoniazid
mshA 575117 c.-231T>C upstream_gene_variant 0.51 ethionamide
isoniazid
mshA 575118 c.-230_-228delACGinsGC upstream_gene_variant 0.51 ethionamide
isoniazid
mshA 575124 c.-224_-222delGGGinsCC upstream_gene_variant 0.51 ethionamide
isoniazid
mshA 575137 c.-211C>G upstream_gene_variant 0.56 ethionamide
isoniazid
mshA 575144 c.-204T>C upstream_gene_variant 0.56 ethionamide
isoniazid
mshA 575154 c.-194_-192delGTGinsCC upstream_gene_variant 0.53 ethionamide
isoniazid
mshA 575161 c.-187T>C upstream_gene_variant 0.54 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.24 ethionamide
isoniazid
mshA 575527 c.180G>C synonymous_variant 0.4 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.46 ethionamide
isoniazid
mshA 575542 c.195C>A synonymous_variant 0.45 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.45 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.45 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.45 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.46 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 0.47 ethionamide
isoniazid
mshA 575587 c.240C>G synonymous_variant 0.46 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.46 ethionamide
isoniazid
mshA 575623 c.276C>G synonymous_variant 0.39 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 0.29 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.37 ethionamide
isoniazid
mshA 575649 p.Val101Ala missense_variant 0.4 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.46 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.44 ethionamide
isoniazid
mshA 575665 c.318G>A synonymous_variant 0.44 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.48 ethionamide
isoniazid
mshA 575695 c.348C>A synonymous_variant 0.46 ethionamide
isoniazid
mshA 575701 c.354G>A synonymous_variant 0.45 ethionamide
isoniazid
mshA 575704 c.357T>G synonymous_variant 0.44 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.45 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.47 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.47 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.51 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.5 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.49 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 0.45 ethionamide
isoniazid
mshA 575755 c.408G>A synonymous_variant 0.42 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.42 ethionamide
isoniazid
mshA 575770 c.423G>A synonymous_variant 0.43 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.43 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.45 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.46 ethionamide
isoniazid
mshA 575809 c.462C>T synonymous_variant 0.59 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.59 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.57 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.59 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.58 ethionamide
isoniazid
mshA 575833 c.486C>G synonymous_variant 0.56 ethionamide
isoniazid
mshA 575845 c.498C>T synonymous_variant 0.59 ethionamide
isoniazid Not assoc w R - Interim
mshA 575864 c.517T>C synonymous_variant 0.65 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.64 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 0.63 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.62 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.61 ethionamide
isoniazid
mshA 575907 p.Ala187Val missense_variant 0.41 ethionamide Not assoc w R
isoniazid Not assoc w R
mshA 575917 p.Asp190Glu missense_variant 0.52 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 0.52 ethionamide
isoniazid
mshA 575924 p.Gly193Ser missense_variant 0.52 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.47 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.39 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>G upstream_gene_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 619561 c.-330G>C upstream_gene_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.42 capreomycin
amikacin
kanamycin
ccsA 619584 c.-307A>T upstream_gene_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 619594 c.-297G>T upstream_gene_variant 0.47 capreomycin
amikacin
kanamycin
ccsA 619609 c.-282G>C upstream_gene_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.4 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 0.39 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>G upstream_gene_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 0.28 capreomycin
amikacin
kanamycin
ccsA 619705 c.-186G>C upstream_gene_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620265 c.375C>G synonymous_variant 0.39 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.3 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 620298 c.408G>C synonymous_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.39 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>T synonymous_variant 0.51 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.49 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.49 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.53 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.51 capreomycin
amikacin
kanamycin
ccsA 620424 c.534G>C synonymous_variant 0.49 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.49 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.47 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>G synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 620625 p.Ile245Met missense_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Uncertain significance
Rv0565c 656052 c.1419A>C synonymous_variant 0.39 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 0.39 ethionamide Uncertain significance
Rv0565c 656076 c.1395C>T synonymous_variant 0.39 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 0.37 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.36 ethionamide
Rv0565c 656091 c.1380T>C synonymous_variant 0.35 ethionamide
Rv0565c 656100 c.1371G>C synonymous_variant 0.36 ethionamide
Rv0565c 656112 c.1359C>G synonymous_variant 0.37 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.43 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.43 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.43 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.4 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.4 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.38 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 0.38 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.23 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 0.35 ethionamide
Rv0565c 656412 c.1059T>C synonymous_variant 0.38 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.44 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.44 ethionamide
Rv0565c 656448 c.1021_1023delATTinsGC frameshift_variant&missense_variant 0.52 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.52 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.5 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.5 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.51 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.5 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.47 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.46 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.42 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.39 ethionamide Not assoc w R - Interim
Rv0565c 656526 p.Glu315Asp missense_variant 0.34 ethionamide
Rv0565c 656535 c.936C>G synonymous_variant 0.27 ethionamide
Rv0565c 656539 p.Ser311Ala missense_variant 0.25 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.21 ethionamide
Rv0565c 656978 p.Ala165Thr missense_variant 0.19 ethionamide
Rv0565c 656983 p.Gly163Asp missense_variant 0.19 ethionamide
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657219 p.Ala84Val missense_variant 0.27 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 0.4 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 0.44 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.49 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.48 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.49 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.51 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.62 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.65 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.63 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.6 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.64 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.63 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.62 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.62 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.68 ethionamide
Rv0565c 657372 c.99G>C synonymous_variant 0.62 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.6 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.52 ethionamide
Rv0565c 657399 c.72G>C synonymous_variant 0.33 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 0.34 ethionamide
Rv0565c 657405 c.64_66delCTGinsAT frameshift_variant&missense_variant 0.33 ethionamide Uncertain significance
Rv0565c 657408 c.63A>C synonymous_variant 0.31 ethionamide
Rv0565c 657560 c.-90G>C upstream_gene_variant 0.26 ethionamide
Rv0565c 657563 c.-93T>C upstream_gene_variant 0.3 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 0.32 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 0.31 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.4 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.47 ethionamide
Rv0565c 657600 c.-132_-131delCA upstream_gene_variant 0.49 ethionamide
Rv0565c 657606 c.-136T>G upstream_gene_variant 0.48 ethionamide
Rv0565c 657607 c.-138_-137insCA upstream_gene_variant 0.49 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.69 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.71 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.7 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.68 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.63 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.6 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.42 ethionamide
hadA 731717 c.-213T>G upstream_gene_variant 0.28 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.47 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.5 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.57 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.59 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.58 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.56 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.52 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.39 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.38 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.34 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.34 isoniazid
hadA 731864 c.-66C>T upstream_gene_variant 0.22 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.22 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.38 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.46 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.49 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.48 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.51 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.65 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.67 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.68 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.67 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.72 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.7 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.67 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.71 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.71 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 0.32 rifampicin Uncertain significance
nusG 734093 c.-161A>C upstream_gene_variant 0.34 rifampicin
nusG 734096 c.-158C>T upstream_gene_variant 0.34 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.34 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.34 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.34 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.35 rifampicin Uncertain significance
nusG 734123 c.-131C>G upstream_gene_variant 0.36 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 0.36 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.35 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.35 rifampicin
nusG 734144 c.-110G>C upstream_gene_variant 0.35 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.33 rifampicin
nusG 734340 c.87T>C synonymous_variant 0.27 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.42 rifampicin
nusG 734360 p.Ala36Val missense_variant 0.53 rifampicin Uncertain significance
nusG 734370 c.117A>G synonymous_variant 0.59 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.6 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.73 rifampicin
nusG 734418 c.165C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
nusG 734421 c.168A>G synonymous_variant 0.76 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.78 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.75 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.76 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.75 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.74 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.75 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.76 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.69 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.67 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.65 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.64 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.5 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.44 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.42 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.43 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.42 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.36 rifampicin
nusG 734658 c.405A>G synonymous_variant 0.27 rifampicin Not assoc w R
nusG 734673 c.420A>G synonymous_variant 0.25 rifampicin
nusG 734676 c.423G>C synonymous_variant 0.24 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
nusG 734680 p.Ala143Thr missense_variant 0.22 rifampicin
nusG 734772 c.519G>C synonymous_variant 0.22 rifampicin
nusG 734775 c.522C>G synonymous_variant 0.24 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.24 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.25 rifampicin
nusG 734787 c.534T>C synonymous_variant 0.27 rifampicin
nusG 734792 p.Val180Ala missense_variant 0.33 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.37 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.67 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.68 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>C synonymous_variant 0.67 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.66 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.68 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.67 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.67 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.61 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.59 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.34 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.32 rifampicin
rpoB 760030 p.Asn75Thr missense_variant 0.2 rifampicin Uncertain significance
rpoB 760034 c.228A>G synonymous_variant 0.26 rifampicin
rpoB 760040 c.234T>C synonymous_variant 0.28 rifampicin
rpoB 760046 c.240G>C synonymous_variant 0.35 rifampicin
rpoB 760060 p.Tyr85Leu missense_variant 0.41 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.46 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.5 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.61 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.64 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.66 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.73 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.68 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.68 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.7 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.69 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.68 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.69 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.65 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.63 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.62 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.56 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.6 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.56 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.61 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.67 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.78 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760680 p.Asn292Asp missense_variant 0.24 rifampicin
rpoB 760683 c.877T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.66 rifampicin
rpoB 760718 c.912C>T synonymous_variant 0.64 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.53 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.46 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.46 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.43 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.42 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.43 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.5 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.54 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.53 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.55 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.61 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.63 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.68 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.66 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.63 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.62 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.62 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.72 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.71 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.78 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.7 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.69 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.67 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.71 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.7 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.67 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.65 rifampicin
rpoB 761373 p.Val523His missense_variant 0.61 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.55 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.43 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.34 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.32 rifampicin
rpoB 761439 c.1633_1635delGACinsAG frameshift_variant&missense_variant 0.33 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.31 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.31 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.32 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.41 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.55 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.6 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.68 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.72 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.74 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.74 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.71 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.61 rifampicin
rpoB 761720 c.1914C>G synonymous_variant 0.33 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.29 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.36 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.46 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.5 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.53 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.53 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.57 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.58 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.65 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.66 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.7 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.64 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.66 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.69 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.79 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.74 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.67 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.65 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.65 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.64 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.65 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.78 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.68 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.68 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.68 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.72 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.83 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.81 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.81 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.79 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.78 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.72 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.7 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.73 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.73 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.68 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.68 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.69 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.71 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.69 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.68 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.65 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.64 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.65 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.66 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.68 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.62 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.61 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.61 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.55 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.36 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.36 rifampicin
rpoC 762758 c.-612G>C upstream_gene_variant 0.26 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.29 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.3 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.32 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.34 rifampicin Uncertain significance
rpoB 762810 c.3004_3006delGCCinsTG frameshift_variant&missense_variant 0.39 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.42 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.64 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.65 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.36 rifampicin Not assoc w R
rpoB 763031 c.3225T>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.65 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.54 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.54 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.56 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.54 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.53 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.52 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.58 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.42 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.4 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763351 c.-19T>C upstream_gene_variant 0.32 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.34 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 0.61 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.67 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.63 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.61 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.68 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.68 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.69 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.68 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.67 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.69 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.7 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.61 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.57 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.59 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.59 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.56 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.56 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.56 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.54 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.56 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.57 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.58 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.56 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.51 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.51 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.53 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.49 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.48 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.43 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.44 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.51 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.56 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.6 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.61 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.6 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.56 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.57 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.59 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.57 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.52 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.52 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.56 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.57 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.36 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.35 rifampicin
rpoC 764392 c.1023C>T synonymous_variant 0.36 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.51 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.53 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.52 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.54 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.63 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.68 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.71 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.7 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.69 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.62 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.55 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.56 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.68 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.67 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.55 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.47 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.55 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.36 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.34 rifampicin
rpoC 765208 c.1839T>C synonymous_variant 0.22 rifampicin
rpoC 765220 c.1851A>G synonymous_variant 0.26 rifampicin
rpoC 765233 p.Ala622Ser missense_variant 0.27 rifampicin
rpoC 765241 c.1872C>T synonymous_variant 0.27 rifampicin
rpoC 765244 c.1875T>C synonymous_variant 0.28 rifampicin
rpoC 765247 c.1878C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765248 c.1879T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765251 c.1882_1884delAGCinsTCG synonymous_variant 0.29 rifampicin
rpoC 765292 c.1923G>C synonymous_variant 0.5 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 0.42 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.41 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.49 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.52 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 0.59 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765364 c.1995G>A synonymous_variant 0.6 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.64 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.7 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.7 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.68 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.67 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.63 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.63 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.66 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.65 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.65 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.67 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.66 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.64 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.64 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.61 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.61 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.63 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.62 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.7 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.7 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.7 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.65 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.67 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.66 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.69 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.69 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.72 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.74 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.69 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.61 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766174 p.Asn935Lys missense_variant 0.26 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.26 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.34 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.34 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.37 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.43 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.49 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.55 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.56 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.55 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.55 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.56 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.57 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.59 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.61 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.61 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.61 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.63 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.67 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.71 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.72 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.69 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.69 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.71 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.62 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.63 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.65 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.69 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.68 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.69 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.69 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.69 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.67 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.67 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.69 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.74 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.68 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.64 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.64 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.71 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.7 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.76 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.72 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.75 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.76 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.76 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.7 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.64 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.63 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.62 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.7 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.73 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.66 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.62 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.23 rifampicin
rpoC 767284 c.3915C>T synonymous_variant 0.2 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 775961 c.2520C>G synonymous_variant 0.26 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.31 clofazimine
bedaquiline
mmpL5 775973 c.2506_2508delTTGinsCC frameshift_variant&missense_variant 0.24 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775981 p.Leu834Met missense_variant 0.31 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.27 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 0.33 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.32 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 0.27 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.31 clofazimine
bedaquiline
mmpL5 776030 c.2451G>A synonymous_variant 0.2 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776182 p.Asp767Asn missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R
mmpL5 776646 p.Val612Thr missense_variant 0.22 clofazimine
bedaquiline
mmpL5 776654 c.1827A>C synonymous_variant 0.28 clofazimine
bedaquiline
mmpL5 776664 p.Thr606Gly missense_variant 0.3 clofazimine
bedaquiline
mmpL5 776675 c.1806G>A synonymous_variant 0.18 clofazimine
bedaquiline
mmpL5 776678 c.1803G>C synonymous_variant 0.35 clofazimine
bedaquiline
mmpL5 776684 c.1797G>A synonymous_variant 0.2 clofazimine
bedaquiline
mmpL5 776693 p.Val596Ala missense_variant 0.35 clofazimine
bedaquiline
mmpL5 776705 c.1776C>T synonymous_variant 0.37 clofazimine
bedaquiline
mmpL5 776738 p.Ile581Met missense_variant 0.3 clofazimine
bedaquiline
mmpL5 776741 c.1740C>G synonymous_variant 0.23 clofazimine
bedaquiline
mmpL5 776756 p.Asp575Glu missense_variant 0.25 clofazimine
bedaquiline
mmpL5 777095 c.1386T>C synonymous_variant 0.29 clofazimine
bedaquiline
mmpL5 777101 c.1380C>G synonymous_variant 0.33 clofazimine
bedaquiline
mmpL5 777110 c.1371T>G synonymous_variant 0.36 clofazimine
bedaquiline
mmpL5 777115 p.Met456Leu missense_variant 0.37 clofazimine
bedaquiline
mmpL5 777116 c.1365C>T synonymous_variant 0.37 clofazimine
bedaquiline
mmpL5 777133 p.Val450Ile missense_variant 0.46 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.54 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.53 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.47 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.46 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.42 clofazimine
bedaquiline
mmpL5 777212 c.1267_1269delGCCinsAG frameshift_variant&missense_variant 0.41 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777215 c.1266C>G synonymous_variant 0.4 clofazimine
bedaquiline
mmpL5 777218 c.1263G>A synonymous_variant 0.41 clofazimine
bedaquiline
mmpL5 777251 c.1230C>G synonymous_variant 0.25 clofazimine
bedaquiline
mmpL5 777254 c.1227G>C synonymous_variant 0.22 clofazimine
bedaquiline
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
rpsL 781182 c.-378G>C upstream_gene_variant 0.25 streptomycin
rpsL 781185 c.-375T>C upstream_gene_variant 0.29 streptomycin
rpsL 781194 c.-366G>C upstream_gene_variant 0.4 streptomycin
rpsL 781197 c.-363A>G upstream_gene_variant 0.4 streptomycin
rpsL 781224 c.-336T>C upstream_gene_variant 0.41 streptomycin
rpsL 781230 c.-330T>C upstream_gene_variant 0.42 streptomycin
rpsL 781232 c.-328C>T upstream_gene_variant 0.42 streptomycin
rpsL 781234 c.-326G>T upstream_gene_variant 0.43 streptomycin
rpsL 781240 c.-320A>T upstream_gene_variant 0.43 streptomycin
rpsL 781257 c.-303G>C upstream_gene_variant 0.41 streptomycin
rpsL 781269 c.-291C>T upstream_gene_variant 0.38 streptomycin
rpsL 781270 c.-290A>C upstream_gene_variant 0.36 streptomycin
rpsL 781276 c.-284A>C upstream_gene_variant 0.33 streptomycin
rpsL 781285 c.-275_-273delACAinsGC upstream_gene_variant 0.25 streptomycin
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.44 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.62 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.62 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.62 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.71 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.73 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.76 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.77 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.71 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.75 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.75 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.78 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.79 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.76 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.75 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.76 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.76 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.75 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.78 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.74 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.73 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.71 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.72 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.72 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.68 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.67 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.68 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.67 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.69 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.72 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.7 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.7 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.47 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.55 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.55 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.59 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.65 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.63 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.63 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.64 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.64 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.62 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.63 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.68 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.67 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.65 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.65 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.66 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.68 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.68 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.63 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.62 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.62 linezolid
rplC 800814 c.6A>G synonymous_variant 0.62 linezolid
rplC 800817 c.9A>T synonymous_variant 0.6 linezolid
rplC 800844 c.36T>C synonymous_variant 0.68 linezolid
rplC 800865 c.57A>G synonymous_variant 0.55 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.54 linezolid
rplC 800874 c.66A>G synonymous_variant 0.52 linezolid
rplC 800875 c.67_69delGTAinsAT frameshift_variant&missense_variant 0.52 linezolid
rplC 800880 c.72A>G synonymous_variant 0.53 linezolid
rplC 800889 c.81C>G synonymous_variant 0.52 linezolid
rplC 800892 c.84G>C synonymous_variant 0.51 linezolid
rplC 800907 c.99C>G synonymous_variant 0.51 linezolid
rplC 800916 c.108A>G synonymous_variant 0.52 linezolid
rplC 800934 c.126C>G synonymous_variant 0.41 linezolid
rplC 800937 c.129A>G synonymous_variant 0.33 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.34 linezolid
rplC 800946 c.138T>C synonymous_variant 0.35 linezolid
rplC 800949 c.141T>C synonymous_variant 0.36 linezolid
rplC 800967 c.159C>G synonymous_variant 0.37 linezolid
rplC 800970 c.162T>C synonymous_variant 0.36 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.44 linezolid
rplC 800985 c.177A>G synonymous_variant 0.45 linezolid
rplC 801004 p.Leu66Val missense_variant 0.29 linezolid
rplC 801009 c.201A>C synonymous_variant 0.3 linezolid
rplC 801127 p.Ala107Thr missense_variant 0.34 linezolid
rplC 801132 c.324T>C synonymous_variant 0.38 linezolid
rplC 801147 c.339T>C synonymous_variant 0.47 linezolid
rplC 801150 c.342G>C synonymous_variant 0.51 linezolid
rplC 801153 c.345G>C synonymous_variant 0.5 linezolid
rplC 801156 c.348T>A synonymous_variant 0.5 linezolid
rplC 801168 c.360C>G synonymous_variant 0.56 linezolid
rplC 801171 c.363A>G synonymous_variant 0.55 linezolid
rplC 801174 c.366T>C synonymous_variant 0.56 linezolid
rplC 801195 c.387G>C synonymous_variant 0.57 linezolid
rplC 801207 c.399C>T synonymous_variant 0.57 linezolid
rplC 801246 c.438C>T synonymous_variant 0.4 linezolid
rplC 801249 c.441T>C synonymous_variant 0.4 linezolid
rplC 801255 c.447C>T synonymous_variant 0.35 linezolid
rplC 801264 c.456C>T synonymous_variant 0.31 linezolid
rplC 801267 c.459A>T synonymous_variant 0.33 linezolid
rplC 801270 c.462T>C synonymous_variant 0.33 linezolid
rplC 801276 c.468G>C synonymous_variant 0.31 linezolid
rplC 801279 c.471G>C synonymous_variant 0.31 linezolid
rplC 801282 c.474G>C synonymous_variant 0.31 linezolid
rplC 801285 c.477G>C synonymous_variant 0.31 linezolid
rplC 801300 c.492C>G synonymous_variant 0.43 linezolid
rplC 801309 c.501C>G synonymous_variant 0.39 linezolid
rplC 801312 c.504G>C synonymous_variant 0.42 linezolid
rplC 801321 c.513C>T synonymous_variant 0.48 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.47 linezolid
rplC 801339 c.531T>C synonymous_variant 0.53 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.52 linezolid
rplC 801348 c.540T>G synonymous_variant 0.57 linezolid
rplC 801357 c.549T>C synonymous_variant 0.63 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.66 linezolid
rplC 801402 c.594T>C synonymous_variant 0.61 linezolid
rplC 801405 c.597T>C synonymous_variant 0.61 linezolid
rplC 801423 c.615G>C synonymous_variant 0.55 linezolid
rplC 801426 c.618C>G synonymous_variant 0.53 linezolid
rplC 801427 p.Met207Val missense_variant 0.53 linezolid
rplC 801438 c.630T>C synonymous_variant 0.58 linezolid
rplC 801442 p.Ile212Val missense_variant 0.58 linezolid
Rv1129c 1254056 p.Asp160Ala missense_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1303470 c.540T>G synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 0.22 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303480 p.Gln184Glu missense_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1303489 c.559C>T synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303497 c.567G>A synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1303501 c.571C>T synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303530 c.600G>A synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.51 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1303944 c.1014G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>A synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1304046 c.1116C>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1304058 c.1128G>A synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304059 c.1129C>T synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>T synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304132 p.Ala401Gly missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304161 p.Arg411Ser missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304187 c.1257T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304223 c.1293G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304226 c.1296C>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304227 p.Met433Leu missense_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304535 c.1605G>A synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.5 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fbiC 1305075 c.2145T>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1305081 c.2151G>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1305090 c.2160C>G synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1305114 c.2184T>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.34 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305177 c.2247A>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1305201 c.2271G>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>A synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>A synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1305234 c.2304G>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 0.35 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1305279 p.His783Gln missense_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1305372 c.2442G>A synonymous_variant 0.31 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305384 c.2454G>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 0.3 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1305430 p.Val834Thr missense_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 0.22 clofazimine
pretomanid
delamanid
sigE 1364856 c.444C>G synonymous_variant 0.28 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 0.31 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.31 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.35 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.43 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 0.45 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.42 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.4 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.31 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 0.22 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.2 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.24 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.29 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.36 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.42 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.46 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.47 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.4 pyrazinamide
sigE 1365087 c.675A>C synonymous_variant 0.39 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 0.39 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 0.38 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.39 pyrazinamide
sigE 1365114 c.702G>A synonymous_variant 0.38 pyrazinamide
sigE 1365117 c.705A>C synonymous_variant 0.35 pyrazinamide
sigE 1365118 c.706C>T synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
sigE 1365135 c.723A>C synonymous_variant 0.26 pyrazinamide
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
atpE 1460816 c.-229T>C upstream_gene_variant 0.43 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.53 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.55 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.55 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.54 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.53 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.56 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.49 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.46 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 0.43 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.43 bedaquiline
atpE 1460915 c.-130C>G upstream_gene_variant 0.31 bedaquiline
atpE 1460918 c.-127A>G upstream_gene_variant 0.27 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.38 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.39 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.39 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.35 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.35 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.45 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.49 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.48 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.44 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.38 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.32 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.32 bedaquiline
atpE 1461275 c.231T>A synonymous_variant 0.19 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.42 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.42 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 0.28 capreomycin
linezolid
rrl 1473419 n.-239T>C upstream_gene_variant 0.28 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 0.27 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.27 capreomycin
linezolid
rrl 1473436 n.-222T>C upstream_gene_variant 0.24 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.24 capreomycin
linezolid
rrl 1473653 n.-5_2delTGTGTTTinsGTGTAA non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.75 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474958 n.1301A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.7 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.67 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
inhA 1673487 c.-715T>C upstream_gene_variant 0.24 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673490 c.-712A>G upstream_gene_variant 0.26 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 0.33 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.35 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.36 ethionamide
isoniazid
inhA 1673568 c.-634C>G upstream_gene_variant 0.31 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.26 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.35 ethionamide
isoniazid
fabG1 1673637 p.Asp66Glu missense_variant 0.32 ethionamide
isoniazid
fabG1 1673641 p.Val68Ile missense_variant 0.35 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 0.43 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.44 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.44 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.46 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.49 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.54 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.57 ethionamide
isoniazid
fabG1 1673710 p.Leu91Ile missense_variant 0.6 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.56 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.48 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.4 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.39 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.38 ethionamide
isoniazid
fabG1 1673890 p.Ala151Ser missense_variant 0.54 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.59 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.61 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.65 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.65 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.66 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.64 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.62 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.58 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 0.51 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.4 ethionamide
isoniazid
inhA 1674015 c.-187C>T upstream_gene_variant 0.32 ethionamide
isoniazid Uncertain significance
inhA 1674018 c.-184G>C upstream_gene_variant 0.3 ethionamide
isoniazid
inhA 1674021 c.-181G>C upstream_gene_variant 0.28 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.28 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.25 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.26 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.35 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 0.4 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.63 ethionamide
isoniazid
inhA 1674114 c.-88T>A upstream_gene_variant 0.58 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.58 ethionamide
isoniazid
inhA 1674126 c.-76G>C upstream_gene_variant 0.57 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.54 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.53 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.53 ethionamide
isoniazid
inhA 1674156 c.-46C>G upstream_gene_variant 0.47 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 0.27 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.29 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.39 ethionamide
isoniazid
inhA 1674504 c.303C>G synonymous_variant 0.51 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.58 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674552 c.351C>G synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.59 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.63 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.6 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.69 ethionamide
isoniazid
inhA 1674672 c.471C>G synonymous_variant 0.66 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674723 c.522C>T synonymous_variant 0.62 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674738 c.537C>G synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 0.51 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 0.48 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674753 c.552G>C synonymous_variant 0.47 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.49 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.51 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.67 ethionamide
isoniazid
inhA 1674855 c.654C>G synonymous_variant 0.63 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674864 c.663C>T synonymous_variant 0.63 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.66 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.63 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 0.59 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674966 c.765T>G synonymous_variant 0.46 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 0.41 ethionamide
isoniazid
inhA 1674987 c.786C>T synonymous_variant 0.28 ethionamide
isoniazid
rpsA 1833515 c.-27_-24delCAACinsAAA upstream_gene_variant 0.25 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.39 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.57 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.71 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.74 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.71 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.69 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.69 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.69 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.68 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.64 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.65 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.65 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.61 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.59 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.58 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.58 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.6 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.6 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.62 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.62 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.68 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.7 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.72 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.72 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.72 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.72 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.56 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.54 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.55 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.57 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.61 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.47 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.45 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.46 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.57 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.66 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.62 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.66 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.62 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.62 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.62 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834510 c.969C>T synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
rpsA 1834513 c.972C>G synonymous_variant 0.62 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.68 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.7 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.67 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.65 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.65 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.67 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.65 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.64 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.62 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.63 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834849 c.1308C>G synonymous_variant 0.38 pyrazinamide
rpsA 1834852 c.1311C>G synonymous_variant 0.35 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.61 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.59 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.58 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.56 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.55 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.54 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.53 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.49 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.35 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.33 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.29 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.25 linezolid
tsnR 1853620 c.15C>T synonymous_variant 0.21 linezolid
tsnR 1853632 c.27G>C synonymous_variant 0.24 linezolid
tsnR 1853636 p.Thr11Ala missense_variant 0.25 linezolid Uncertain significance
tsnR 1853656 c.51T>C synonymous_variant 0.26 linezolid
tsnR 1853662 c.57A>C synonymous_variant 0.27 linezolid
tsnR 1853665 c.60C>G synonymous_variant 0.27 linezolid
tsnR 1853668 c.63G>C synonymous_variant 0.28 linezolid
tsnR 1853671 c.66C>T synonymous_variant 0.29 linezolid
tsnR 1853680 c.75A>G synonymous_variant 0.29 linezolid
tsnR 1853686 c.81T>C synonymous_variant 0.29 linezolid
tsnR 1853701 c.96C>G synonymous_variant 0.26 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917940 p.Val1Met missense_variant 0.21 capreomycin
tlyA 1917945 c.6A>T synonymous_variant 0.22 capreomycin
tlyA 1917951 c.12T>C synonymous_variant 0.26 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.31 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.32 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.31 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.32 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>G synonymous_variant 0.31 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.34 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.32 capreomycin
tlyA 1918048 p.Leu37Met missense_variant 0.25 capreomycin
tlyA 1918053 c.114G>C synonymous_variant 0.26 capreomycin
tlyA 1918212 c.273A>G synonymous_variant 0.21 capreomycin
tlyA 1918236 c.297A>C synonymous_variant 0.24 capreomycin
tlyA 1918248 c.309T>C synonymous_variant 0.27 capreomycin
tlyA 1918251 c.312T>G synonymous_variant 0.26 capreomycin
tlyA 1918271 p.Ala111Val missense_variant 0.26 capreomycin
tlyA 1918275 c.336T>C synonymous_variant 0.25 capreomycin
tlyA 1918278 c.339C>G synonymous_variant 0.29 capreomycin
tlyA 1918310 p.Asn124Ser missense_variant 0.25 capreomycin
tlyA 1918326 c.387G>C synonymous_variant 0.23 capreomycin
tlyA 1918330 p.Leu131Val missense_variant 0.24 capreomycin
tlyA 1918346 p.Ala136Val missense_variant 0.21 capreomycin
tlyA 1918352 p.Gly138Asp missense_variant 0.21 capreomycin
tlyA 1918359 c.420A>G synonymous_variant 0.22 capreomycin
tlyA 1918362 c.423G>C synonymous_variant 0.23 capreomycin
tlyA 1918422 c.483T>C synonymous_variant 0.28 capreomycin
tlyA 1918425 c.486C>A synonymous_variant 0.24 capreomycin
tlyA 1918434 c.495C>G synonymous_variant 0.22 capreomycin
tlyA 1918457 p.Arg173His missense_variant 0.2 capreomycin
tlyA 1918476 c.537A>C synonymous_variant 0.22 capreomycin
tlyA 1918477 p.Leu180Met missense_variant 0.22 capreomycin
tlyA 1918488 c.549G>A synonymous_variant 0.21 capreomycin
bacA 2063229 c.1500G>A synonymous_variant 0.22 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063259 p.Glu490Asp missense_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063265 p.Gly488Asp missense_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063271 c.1458G>T synonymous_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063275 p.His485Cys missense_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063280 c.1449C>G synonymous_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063283 c.1446G>A synonymous_variant 0.3 streptomycin Not assoc w R - Interim
kanamycin
capreomycin
amikacin
bacA 2063289 c.1440A>C synonymous_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063303 c.1426C>T synonymous_variant 0.29 streptomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
bacA 2063307 c.1422G>C synonymous_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063313 c.1416T>C synonymous_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.51 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.47 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101744 p.Asp433Glu missense_variant 0.3 ethionamide
delamanid
isoniazid
ndh 2101756 c.1287G>C synonymous_variant 0.36 ethionamide
delamanid
isoniazid
ndh 2101765 c.1278C>G synonymous_variant 0.39 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>A synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>G synonymous_variant 0.39 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2101774 c.1269T>C synonymous_variant 0.39 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.39 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>A synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.39 ethionamide
delamanid
isoniazid
ndh 2101808 p.Thr412Ser missense_variant 0.37 ethionamide
delamanid
isoniazid
ndh 2101830 p.Ile405Val missense_variant 0.46 ethionamide
delamanid
isoniazid
ndh 2101837 p.Ala402Val missense_variant 0.29 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101885 c.1158G>A synonymous_variant 0.28 ethionamide
delamanid
isoniazid
ndh 2101888 c.1155T>C synonymous_variant 0.26 ethionamide
delamanid
isoniazid
ndh 2101891 c.1152C>G synonymous_variant 0.27 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101912 c.1131G>C synonymous_variant 0.54 ethionamide
delamanid
isoniazid
ndh 2101920 c.1123A>C synonymous_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 0.5 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>G synonymous_variant 0.51 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 0.5 ethionamide
delamanid
isoniazid
ndh 2101963 c.1080G>A synonymous_variant 0.49 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101966 c.1077T>G synonymous_variant 0.49 ethionamide
delamanid
isoniazid
ndh 2101972 c.1071G>C synonymous_variant 0.48 ethionamide
delamanid
isoniazid
ndh 2101988 p.Ala352Asp missense_variant 0.41 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2101993 c.1050A>G synonymous_variant 0.37 ethionamide
delamanid
isoniazid
ndh 2102011 c.1032C>G synonymous_variant 0.26 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102014 c.1029C>G synonymous_variant 0.24 ethionamide
delamanid
isoniazid
ndh 2102020 c.1023A>G synonymous_variant 0.22 ethionamide
delamanid
isoniazid
ndh 2102023 c.1020G>C synonymous_variant 0.21 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102026 c.1017G>C synonymous_variant 0.21 ethionamide
delamanid
isoniazid
ndh 2102206 c.837G>C synonymous_variant 0.43 ethionamide
delamanid
isoniazid
ndh 2102212 c.831G>C synonymous_variant 0.43 ethionamide
delamanid
isoniazid
ndh 2102218 c.825C>A synonymous_variant 0.48 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>T synonymous_variant 0.51 ethionamide
delamanid
isoniazid
ndh 2102230 c.813G>C synonymous_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.52 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102302 c.741G>C synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>C synonymous_variant 0.39 ethionamide
delamanid
isoniazid
ndh 2102314 c.729C>T synonymous_variant 0.29 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 0.28 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 0.18 ethionamide
delamanid
isoniazid
ndh 2102623 c.420C>G synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102638 c.405A>C synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 0.41 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 0.42 ethionamide
delamanid
isoniazid
ndh 2102695 c.348C>T synonymous_variant 0.42 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 0.41 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>T synonymous_variant 0.39 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102893 c.150G>C synonymous_variant 0.24 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 0.22 ethionamide
delamanid
isoniazid
katG 2155626 c.486G>C synonymous_variant 1.0 isoniazid
katG 2155632 c.480A>C synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 1.0 isoniazid
katG 2155677 c.435C>G synonymous_variant 1.0 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 c.417C>G synonymous_variant 1.0 isoniazid
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
katG 2155740 p.Gly124Gln missense_variant 1.0 isoniazid
katG 2155743 c.369G>C synonymous_variant 1.0 isoniazid
katG 2155782 c.330C>G synonymous_variant 1.0 isoniazid
katG 2155785 c.327T>C synonymous_variant 1.0 isoniazid
katG 2155794 p.Ala106Ser missense_variant 1.0 isoniazid
katG 2155806 c.306T>C synonymous_variant 1.0 isoniazid
katG 2155827 c.285C>T synonymous_variant 1.0 isoniazid
katG 2155836 c.276C>G synonymous_variant 1.0 isoniazid
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
pncA 2289892 c.-651C>G upstream_gene_variant 0.21 pyrazinamide
pncA 2289895 c.-654C>G upstream_gene_variant 0.28 pyrazinamide
pncA 2289906 c.-665T>C upstream_gene_variant 0.32 pyrazinamide
pncA 2289907 c.-666A>C upstream_gene_variant 0.32 pyrazinamide
pncA 2289913 c.-672T>C upstream_gene_variant 0.39 pyrazinamide
pncA 2289925 c.-684T>C upstream_gene_variant 0.46 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 0.46 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 0.51 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 0.48 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 0.49 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.53 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.54 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.49 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.5 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.51 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.47 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.46 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 0.42 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 0.41 pyrazinamide
pncA 2290038 c.-797G>A upstream_gene_variant 0.41 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 0.39 pyrazinamide
pncA 2290069 c.-828C>A upstream_gene_variant 0.24 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.58 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.48 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.47 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.29 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.26 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.33 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.36 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.4 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.54 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.6 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.63 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.64 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.56 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.49 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.3 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 0.22 isoniazid
kasA 2518263 p.Phe50Tyr missense_variant 0.18 isoniazid
kasA 2518265 p.Val51Ile missense_variant 0.18 isoniazid
kasA 2518429 c.315A>C synonymous_variant 0.26 isoniazid
kasA 2518439 c.325_327delGCCinsTG frameshift_variant&missense_variant 0.28 isoniazid
kasA 2518444 c.330T>C synonymous_variant 0.29 isoniazid
kasA 2518447 c.333T>G synonymous_variant 0.34 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.44 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.46 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.51 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.58 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.56 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.55 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.58 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.57 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.59 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.61 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.63 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.53 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.48 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.43 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.43 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.43 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.45 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.46 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.44 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.38 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.34 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.36 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.47 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.49 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.47 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.46 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.45 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.45 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.51 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.51 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.55 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.6 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.63 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.62 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.61 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.6 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.62 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.62 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.61 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.65 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.61 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.63 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.58 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.57 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.55 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.51 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.48 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.36 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.33 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.33 isoniazid
kasA 2518951 c.837G>C synonymous_variant 0.32 isoniazid
kasA 2518954 c.840C>G synonymous_variant 0.34 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.33 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.33 isoniazid
kasA 2518975 c.861C>G synonymous_variant 0.3 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.34 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.37 isoniazid
kasA 2518993 c.879C>G synonymous_variant 0.37 isoniazid
kasA 2518999 c.885G>C synonymous_variant 0.38 isoniazid
kasA 2519008 c.894C>G synonymous_variant 0.31 isoniazid
kasA 2519017 c.903G>C synonymous_variant 0.3 isoniazid
kasA 2519020 c.906G>C synonymous_variant 0.3 isoniazid
kasA 2519021 p.Ala303Lys missense_variant 0.29 isoniazid
kasA 2519027 c.913_915delATCinsGT frameshift_variant&missense_variant 0.31 isoniazid
kasA 2519050 c.936C>G synonymous_variant 0.46 isoniazid
kasA 2519053 c.939G>C synonymous_variant 0.45 isoniazid
kasA 2519056 c.942G>C synonymous_variant 0.44 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.48 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.52 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.59 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.66 isoniazid
kasA 2519108 c.994_996delGATinsCG frameshift_variant&missense_variant 0.66 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.65 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.58 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.61 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.59 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.57 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 0.45 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 0.33 isoniazid
kasA 2519218 c.1104G>A synonymous_variant 0.29 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 0.3 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 0.3 isoniazid
kasA 2519230 c.1116C>T synonymous_variant 0.31 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 0.29 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.28 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 0.28 isoniazid
ahpC 2726198 c.6A>T synonymous_variant 0.19 isoniazid
ahpC 2726204 c.12A>G synonymous_variant 0.26 isoniazid
ahpC 2726210 c.18T>C synonymous_variant 0.28 isoniazid Not assoc w R - Interim
ahpC 2726216 c.24T>C synonymous_variant 0.34 isoniazid
ahpC 2726219 c.27A>G synonymous_variant 0.36 isoniazid
ahpC 2726232 p.Gln14Glu missense_variant 0.33 isoniazid
ahpC 2726243 c.51T>G synonymous_variant 0.32 isoniazid
ahpC 2726244 c.52_54delCTCinsTG frameshift_variant&missense_variant 0.32 isoniazid Uncertain significance
ahpC 2726251 p.Gly20Ala missense_variant 0.31 isoniazid Uncertain significance
ahpC 2726255 c.63T>C synonymous_variant 0.32 isoniazid Not assoc w R - Interim
ahpC 2726258 c.66C>T synonymous_variant 0.33 isoniazid Not assoc w R - Interim
ahpC 2726303 c.111T>C synonymous_variant 0.35 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.31 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.29 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.29 isoniazid
ahpC 2726322 c.130_132delCCAinsGC frameshift_variant&missense_variant 0.29 isoniazid Uncertain significance
ahpC 2726330 c.138G>A synonymous_variant 0.31 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 0.33 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.43 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.41 isoniazid Not assoc w R - Interim
ahpC 2726528 c.336C>G synonymous_variant 0.27 isoniazid
ahpC 2726540 c.348C>G synonymous_variant 0.3 isoniazid
ahpC 2726543 c.351A>G synonymous_variant 0.31 isoniazid
ahpC 2726546 c.354C>G synonymous_variant 0.32 isoniazid
ahpC 2726551 p.Gln120Leu missense_variant 0.3 isoniazid
ahpC 2726556 c.364_366delGCAinsAC frameshift_variant&missense_variant 0.28 isoniazid Uncertain significance
ahpC 2726564 c.372C>G synonymous_variant 0.38 isoniazid Not assoc w R - Interim
ahpC 2726591 c.399C>G synonymous_variant 0.47 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.47 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.45 isoniazid
ahpC 2726601 p.Ile137Leu missense_variant 0.47 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.57 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.56 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.61 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.53 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.51 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.5 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.49 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.46 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.45 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.47 isoniazid
ahpC 2726717 c.525A>G synonymous_variant 0.38 isoniazid
folC 2746308 p.Arg431Ser missense_variant 0.21 para-aminosalicylic_acid
folC 2746375 c.1224G>C synonymous_variant 0.21 para-aminosalicylic_acid
folC 2746390 c.1209G>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.26 para-aminosalicylic_acid
folC 2746401 p.Ser400Ala missense_variant 0.29 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.29 para-aminosalicylic_acid
folC 2746414 c.1183_1185delGAGinsCA frameshift_variant&missense_variant 0.32 para-aminosalicylic_acid
folC 2746420 c.1179A>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.37 para-aminosalicylic_acid
folC 2746471 c.1128C>A synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746478 p.Phe374Tyr missense_variant 0.25 para-aminosalicylic_acid
folC 2746651 c.948T>C synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 0.25 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 0.41 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.52 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.51 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.52 para-aminosalicylic_acid
folC 2747071 c.528C>G synonymous_variant 0.55 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.55 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.53 para-aminosalicylic_acid
folC 2747101 c.498G>C synonymous_variant 0.53 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.52 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.48 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.48 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 0.47 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.28 para-aminosalicylic_acid
folC 2747248 c.351G>C synonymous_variant 0.28 para-aminosalicylic_acid
folC 2747264 p.Gly112Ala missense_variant 0.48 para-aminosalicylic_acid
folC 2747266 c.333C>T synonymous_variant 0.53 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.55 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.55 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.55 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747302 c.297A>C synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.66 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.6 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.51 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.51 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.49 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 0.3 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.26 para-aminosalicylic_acid
folC 2747726 c.-128G>A upstream_gene_variant 0.19 para-aminosalicylic_acid
folC 2747739 c.-141G>A upstream_gene_variant 0.27 para-aminosalicylic_acid
folC 2747745 c.-147A>C upstream_gene_variant 0.28 para-aminosalicylic_acid
folC 2747748 c.-150C>G upstream_gene_variant 0.28 para-aminosalicylic_acid
folC 2747751 c.-154_-153delGCinsCG upstream_gene_variant 0.3 para-aminosalicylic_acid
folC 2747759 c.-161T>C upstream_gene_variant 0.34 para-aminosalicylic_acid
folC 2747760 c.-162G>T upstream_gene_variant 0.35 para-aminosalicylic_acid
folC 2747772 c.-174C>G upstream_gene_variant 0.37 para-aminosalicylic_acid
folC 2747790 c.-192G>C upstream_gene_variant 0.39 para-aminosalicylic_acid
Rv2477c 2782423 c.1620C>G synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782432 c.1609_1611delGTGinsAC frameshift_variant&missense_variant 0.38 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782441 c.1602G>A synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782450 c.1593C>A synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782513 c.1530G>T synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782695 c.1348A>C synonymous_variant 0.26 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782822 c.1221G>A synonymous_variant 0.21 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782841 p.Thr401Asn missense_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 0.5 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782894 c.1149C>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782930 c.1113G>A synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.62 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.56 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>A synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783047 p.Asp332Gly missense_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.58 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.56 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783107 c.936G>A synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.7 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.68 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.68 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.58 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 0.22 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783431 c.610_612delAGCinsTA frameshift_variant&missense_variant 0.22 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783437 c.606G>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783497 c.544_546delTTGinsCC frameshift_variant&missense_variant 0.49 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783502 c.541T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.56 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783521 c.522G>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.57 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.66 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784048 c.-6C>T upstream_gene_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784051 c.-9C>A upstream_gene_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784052 c.-10A>C upstream_gene_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784345 c.-303G>A upstream_gene_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784357 c.-316_-315delTTinsAC upstream_gene_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784366 c.-324G>T upstream_gene_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784390 c.-348G>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784435 c.-393C>G upstream_gene_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784507 c.-465C>G upstream_gene_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784511 c.-470_-469delAGinsGC upstream_gene_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784513 c.-471C>G upstream_gene_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784540 c.-498G>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784551 c.-509G>A upstream_gene_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2860446 c.-28T>A upstream_gene_variant 0.19 clofazimine
bedaquiline
pepQ 2860475 c.-57C>T upstream_gene_variant 0.21 clofazimine
bedaquiline
pepQ 2860480 c.-62G>A upstream_gene_variant 0.22 clofazimine
bedaquiline
pepQ 2860483 c.-65A>T upstream_gene_variant 0.21 clofazimine
bedaquiline
pepQ 2860490 c.-72G>C upstream_gene_variant 0.2 clofazimine
bedaquiline
ribD 2987026 p.Ala63Gly missense_variant 0.31 para-aminosalicylic_acid
ribD 2987033 c.195C>G synonymous_variant 0.33 para-aminosalicylic_acid
ribD 2987042 c.204A>G synonymous_variant 0.36 para-aminosalicylic_acid
ribD 2987046 p.Val70Ile missense_variant 0.35 para-aminosalicylic_acid
ribD 2987058 c.220T>C synonymous_variant 0.33 para-aminosalicylic_acid
ribD 2987066 c.228A>G synonymous_variant 0.38 para-aminosalicylic_acid
ribD 2987069 c.231T>C synonymous_variant 0.42 para-aminosalicylic_acid
ribD 2987092 p.Val85Ala missense_variant 0.51 para-aminosalicylic_acid
ribD 2987105 c.267C>G synonymous_variant 0.51 para-aminosalicylic_acid
ribD 2987108 c.270T>C synonymous_variant 0.49 para-aminosalicylic_acid
ribD 2987123 c.285C>G synonymous_variant 0.38 para-aminosalicylic_acid
ribD 2987125 p.Val96Ala missense_variant 0.36 para-aminosalicylic_acid
ribD 2987128 p.Arg97Gln missense_variant 0.36 para-aminosalicylic_acid
ribD 2987130 p.Met98Leu missense_variant 0.37 para-aminosalicylic_acid
ribD 2987135 c.297T>C synonymous_variant 0.37 para-aminosalicylic_acid
ribD 2987137 p.Val100Ala missense_variant 0.36 para-aminosalicylic_acid
ribD 2987140 p.Val101Ala missense_variant 0.36 para-aminosalicylic_acid
Rv2680 2996335 p.Glu77Asp missense_variant 0.32 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.36 capreomycin
Rv2681 2996368 c.-371T>C upstream_gene_variant 0.33 capreomycin
Rv2681 2996374 c.-365G>C upstream_gene_variant 0.28 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 0.25 capreomycin
Rv2681 2996380 c.-359C>G upstream_gene_variant 0.25 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 0.26 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 0.26 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>G upstream_gene_variant 0.26 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.27 capreomycin
Rv2681 2996404 c.-335T>C upstream_gene_variant 0.29 capreomycin
Rv2680 2996408 p.Leu102Met missense_variant 0.27 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.3 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.29 capreomycin
Rv2681 2996894 c.156A>G synonymous_variant 0.28 capreomycin
Rv2681 2996906 c.168A>G synonymous_variant 0.4 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 0.48 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 0.48 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 0.49 capreomycin
Rv2681 2996966 c.228G>C synonymous_variant 0.42 capreomycin
Rv2681 2996972 c.234C>G synonymous_variant 0.4 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 0.38 capreomycin
Rv2681 2996976 p.Ala80Ser missense_variant 0.37 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 0.37 capreomycin
Rv2681 2997002 c.264C>G synonymous_variant 0.31 capreomycin
Rv2681 2997242 c.504C>G synonymous_variant 0.27 capreomycin
Rv2681 2997271 p.Ala178Asp missense_variant 0.23 capreomycin
Rv2681 2997278 c.540G>C synonymous_variant 0.27 capreomycin
Rv2681 2997281 c.543C>T synonymous_variant 0.31 capreomycin
Rv2681 2997287 c.549G>C synonymous_variant 0.34 capreomycin
Rv2681 2997291 c.553T>C synonymous_variant 0.37 capreomycin
Rv2681 2997314 c.576A>G synonymous_variant 0.36 capreomycin
Rv2681 2997317 c.579A>G synonymous_variant 0.37 capreomycin
Rv2681 2997330 p.Ser198Ala missense_variant 0.25 capreomycin
Rv2681 2997333 p.Arg199Glu missense_variant 0.25 capreomycin
Rv2681 2997338 c.600G>C synonymous_variant 0.26 capreomycin
Rv2681 2997341 c.603G>C synonymous_variant 0.25 capreomycin
Rv2681 2997346 p.Glu203Gly missense_variant 0.27 capreomycin
Rv2681 2997350 c.612A>G synonymous_variant 0.27 capreomycin Not assoc w R - Interim
Rv2681 2997368 c.630T>C synonymous_variant 0.27 capreomycin
Rv2681 2997371 c.633G>A synonymous_variant 0.27 capreomycin
Rv2752c 3064831 p.Ala454Asn missense_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064836 c.1354_1356delTTGinsCC frameshift_variant&missense_variant 0.27 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064860 c.1332G>C synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064863 c.1329G>C synonymous_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064872 c.1320T>G synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064877 p.Ser439Ala missense_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064893 c.1299C>G synonymous_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064896 c.1296T>C synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>G synonymous_variant 0.3 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064926 c.1264_1266delTTGinsCC frameshift_variant&missense_variant 0.25 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064932 c.1260T>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064935 c.1257A>G synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 0.26 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064947 c.1245A>G synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064956 c.1234_1236delAGTinsCC frameshift_variant&missense_variant 0.31 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064962 c.1230C>G synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064973 p.Ala407Ser missense_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064995 c.1197C>G synonymous_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>G synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065007 c.1185G>C synonymous_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065013 c.1179G>C synonymous_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065018 p.Asn392His missense_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065022 c.1170G>A synonymous_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065028 c.1162_1164delGTGinsAC frameshift_variant&missense_variant 0.38 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065040 c.1152C>G synonymous_variant 0.42 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.37 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065052 c.1140G>A synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.28 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065082 c.1110G>T synonymous_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065088 c.1104A>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 0.27 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065115 c.1077C>G synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065166 c.1026C>G synonymous_variant 0.33 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065183 p.Ser337Ala missense_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065397 c.795G>C synonymous_variant 0.3 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065400 c.792A>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065415 c.777G>A synonymous_variant 0.32 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065418 c.774A>G synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065421 c.771G>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065442 c.750T>C synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065451 c.741G>A synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>C synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>C synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065916 c.276T>C synonymous_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065925 p.Ala89Gly missense_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065928 c.264G>C synonymous_variant 0.43 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065946 p.Gly82Ala missense_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsCC frameshift_variant&missense_variant 0.53 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065979 c.213T>C synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065988 c.204A>G synonymous_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.44 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066002 p.Met64Leu missense_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066003 c.189C>T synonymous_variant 0.33 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin
isoniazid
Rv2752c 3066009 c.183G>C synonymous_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.32 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 0.3 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066093 c.99T>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Ser missense_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066150 c.42C>A synonymous_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066153 c.37_39delTCCinsAT frameshift_variant&missense_variant 0.19 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066162 c.30C>A synonymous_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066321 c.-130C>A upstream_gene_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066351 c.-160G>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066357 c.-166G>C upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066360 c.-169T>C upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066369 c.-180_-178delAGCinsGCG upstream_gene_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.32 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066398 c.-207G>A upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066400 c.-210_-209delATinsTC upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066482 c.-291G>T upstream_gene_variant 0.17 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>C upstream_gene_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066734 c.-543G>A upstream_gene_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066954 c.-763G>A upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066969 c.-778G>C upstream_gene_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>G upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066987 c.-796C>T upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066994 c.-804_-803delCAinsGC upstream_gene_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066996 c.-805T>C upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067001 c.-810G>A upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067017 c.-827_-826delGGinsAC upstream_gene_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067020 c.-829G>C upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067023 c.-832G>C upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067232 c.714C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067246 p.Thr234Ala missense_variant 0.35 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 0.36 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 0.35 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067281 p.Val222Ala missense_variant 0.43 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.44 para-aminosalicylic_acid
thyX 3067286 c.660C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 0.49 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067313 c.633G>T synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067442 c.504C>T synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067462 c.484C>T synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.55 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067510 c.436C>T synonymous_variant 0.48 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.5 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.45 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.52 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.56 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.58 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.6 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.6 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.65 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.63 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.41 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.61 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.62 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 0.66 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.66 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.68 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.63 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067877 c.69G>C synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.62 para-aminosalicylic_acid
thyX 3067935 p.Thr4Ile missense_variant 0.33 para-aminosalicylic_acid
thyA 3073812 c.660C>G synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3073815 c.657G>A synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3073824 c.648A>G synonymous_variant 0.49 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 0.49 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3073872 c.598_600delATCinsGG frameshift_variant&missense_variant 0.55 para-aminosalicylic_acid
thyA 3073890 c.580_582delTTGinsCA frameshift_variant&missense_variant 0.54 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.53 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.48 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3073941 c.531C>T synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.41 para-aminosalicylic_acid
thyA 3074055 p.Glu139Pro missense_variant 0.41 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074079 c.393G>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 0.27 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.32 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074147 p.Ile109Val missense_variant 0.29 para-aminosalicylic_acid
thyA 3074153 p.Glu107Gln missense_variant 0.26 para-aminosalicylic_acid
thyA 3074157 c.313_315delTCCinsAG frameshift_variant&stop_gained 0.28 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAG frameshift_variant&missense_variant 0.28 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.51 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.51 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.49 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074262 p.Gly70Ala missense_variant 0.29 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.26 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074391 c.81C>A synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3074397 c.75A>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074423 p.Pro17Ala missense_variant 0.28 para-aminosalicylic_acid
thyA 3074427 c.45T>A synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3074431 p.Thr14Lys missense_variant 0.21 para-aminosalicylic_acid
thyA 3074477 c.-6T>C upstream_gene_variant 0.24 para-aminosalicylic_acid
thyA 3074490 c.-19G>A upstream_gene_variant 0.21 para-aminosalicylic_acid
thyA 3074495 c.-24C>T upstream_gene_variant 0.85 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.28 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.27 cycloserine
ald 3087726 p.Ala303Ser missense_variant 0.25 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.23 cycloserine
ald 3087737 c.918G>C synonymous_variant 0.25 cycloserine
ald 3087749 c.930C>G synonymous_variant 0.25 cycloserine
ald 3087750 p.Tyr311Val missense_variant 0.24 cycloserine
ald 3087761 c.942C>G synonymous_variant 0.24 cycloserine
ald 3087770 c.951G>C synonymous_variant 0.24 cycloserine
whiB7 3569096 c.-429_-418delACCGGGCCTGTA upstream_gene_variant 0.49 streptomycin
amikacin
kanamycin
whiB7 3569112 c.-436_-434delGAC upstream_gene_variant 0.43 streptomycin
amikacin
kanamycin
whiB7 3569132 c.-453C>G upstream_gene_variant 0.43 streptomycin
amikacin
kanamycin
whiB7 3569142 c.-465_-463delTCGinsCC upstream_gene_variant 0.38 streptomycin
amikacin
kanamycin
whiB7 3569145 c.-466A>C upstream_gene_variant 0.4 streptomycin
amikacin
kanamycin
whiB7 3569151 c.-472A>G upstream_gene_variant 0.41 streptomycin
amikacin
kanamycin
whiB7 3569166 c.-487C>G upstream_gene_variant 0.4 streptomycin
amikacin
kanamycin
whiB7 3569169 c.-490T>C upstream_gene_variant 0.4 streptomycin
amikacin
kanamycin
whiB7 3569181 c.-502C>T upstream_gene_variant 0.31 streptomycin
amikacin
kanamycin
whiB7 3569197 c.-518C>A upstream_gene_variant 0.21 streptomycin
amikacin
kanamycin
whiB7 3569206 c.-527C>A upstream_gene_variant 0.22 streptomycin
amikacin
kanamycin
whiB7 3569226 c.-547G>C upstream_gene_variant 0.22 streptomycin
amikacin
kanamycin
whiB7 3569235 c.-556C>G upstream_gene_variant 0.22 streptomycin
amikacin
kanamycin
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0 pyrazinamide Not assoc w R - Interim
lpqB 3623329 p.Ser528Ala missense_variant 0.21 bedaquiline
rifampicin
lpqB 3623356 p.Leu519Ile missense_variant 0.35 bedaquiline
rifampicin
lpqB 3623360 c.1551A>G synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3623363 c.1548T>C synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3623366 c.1545T>G synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3623369 c.1542G>C synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3623372 c.1539G>T synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3623379 p.Ala511Asn missense_variant 0.35 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3623417 c.1494A>C synonymous_variant 0.3 bedaquiline
rifampicin
lpqB 3623423 c.1488C>G synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623549 c.1362C>G synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3623555 c.1354_1356delGGGinsAC frameshift_variant&missense_variant 0.28 bedaquiline
rifampicin Uncertain significance
lpqB 3623561 c.1350T>C synonymous_variant 0.29 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 0.32 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3623576 c.1335T>C synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 0.34 bedaquiline
rifampicin
lpqB 3623630 c.1281G>C synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3623648 c.1263A>G synonymous_variant 0.39 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 0.36 bedaquiline
rifampicin
lpqB 3623660 c.1251A>C synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3623666 c.1245A>G synonymous_variant 0.29 bedaquiline
rifampicin
lpqB 3623669 c.1242G>C synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3623676 p.Val412Asn missense_variant 0.28 bedaquiline
rifampicin
lpqB 3623682 p.Thr410Gly missense_variant 0.27 bedaquiline
rifampicin
lpqB 3623684 c.1227T>C synonymous_variant 0.27 bedaquiline
rifampicin
lpqB 3623703 p.Ala403Val missense_variant 0.31 bedaquiline
rifampicin
lpqB 3623942 c.969A>G synonymous_variant 0.26 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623950 p.Val321Leu missense_variant 0.27 bedaquiline
rifampicin
lpqB 3623953 c.958T>C synonymous_variant 0.25 bedaquiline
rifampicin
lpqB 3623966 c.945G>C synonymous_variant 0.24 bedaquiline
rifampicin
lpqB 3623970 p.Ala314Gly missense_variant 0.25 bedaquiline
rifampicin
lpqB 3623975 c.936T>C synonymous_variant 0.26 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623987 c.924G>C synonymous_variant 0.38 bedaquiline
rifampicin
lpqB 3623990 c.921G>C synonymous_variant 0.39 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623993 c.918C>T synonymous_variant 0.48 bedaquiline
rifampicin
lpqB 3624014 c.897T>C synonymous_variant 0.49 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624026 p.Glu295Asp missense_variant 0.45 bedaquiline
rifampicin
lpqB 3624030 p.Ala294Arg missense_variant 0.37 bedaquiline
rifampicin
lpqB 3624032 c.879T>C synonymous_variant 0.36 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624035 c.874_876delAGGinsCA frameshift_variant&missense_variant 0.37 bedaquiline
rifampicin Uncertain significance
lpqB 3624041 p.Glu290Asp missense_variant 0.38 bedaquiline
rifampicin
lpqB 3624050 c.861C>G synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3624077 c.834G>A synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624082 c.829A>C synonymous_variant 0.48 bedaquiline
rifampicin
lpqB 3624086 c.825C>T synonymous_variant 0.49 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624092 c.817_819delAGGinsCC frameshift_variant&missense_variant 0.43 bedaquiline
rifampicin Uncertain significance
lpqB 3624100 c.811T>C synonymous_variant 0.4 bedaquiline
rifampicin
lpqB 3624101 c.810C>G synonymous_variant 0.41 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 0.44 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624119 c.792C>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624124 p.Leu263Val missense_variant 0.45 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.46 bedaquiline
rifampicin
lpqB 3624143 c.768T>C synonymous_variant 0.55 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.5 bedaquiline
rifampicin
lpqB 3624185 c.726C>T synonymous_variant 0.52 bedaquiline
rifampicin
lpqB 3624194 c.717C>G synonymous_variant 0.55 bedaquiline
rifampicin
lpqB 3624200 c.711A>G synonymous_variant 0.53 bedaquiline
rifampicin
lpqB 3624204 p.Ser236Asn missense_variant 0.51 bedaquiline
rifampicin
lpqB 3624209 c.702A>C synonymous_variant 0.49 bedaquiline
rifampicin
lpqB 3624224 c.687T>C synonymous_variant 0.45 bedaquiline
rifampicin
lpqB 3624371 c.540T>C synonymous_variant 0.39 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 0.49 bedaquiline
rifampicin
lpqB 3624404 c.507G>T synonymous_variant 0.49 bedaquiline
rifampicin
lpqB 3624407 c.504C>T synonymous_variant 0.48 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624410 c.501C>T synonymous_variant 0.48 bedaquiline
rifampicin
lpqB 3624416 c.495G>A synonymous_variant 0.52 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 0.51 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 0.49 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 0.51 bedaquiline
rifampicin
lpqB 3624437 c.474G>A synonymous_variant 0.55 bedaquiline
rifampicin
lpqB 3624461 c.450C>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 0.42 bedaquiline
rifampicin
lpqB 3624482 c.429T>C synonymous_variant 0.31 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624485 p.Asp142Gly missense_variant 0.24 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624491 c.420G>C synonymous_variant 0.26 bedaquiline
rifampicin
lpqB 3624512 c.399C>G synonymous_variant 0.25 bedaquiline
rifampicin
lpqB 3624515 c.396G>C synonymous_variant 0.23 bedaquiline
rifampicin
lpqB 3624521 c.390G>C synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3624707 c.204G>C synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 0.54 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.56 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 0.48 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 0.45 bedaquiline
rifampicin Uncertain significance
lpqB 3624770 c.141T>C synonymous_variant 0.41 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 0.41 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 0.41 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 0.37 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3624807 p.Val35Ala missense_variant 0.26 bedaquiline
rifampicin
lpqB 3624812 c.99T>G synonymous_variant 0.21 bedaquiline
rifampicin
mtrB 3625032 c.1582C>T synonymous_variant 0.35 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625054 c.-144C>G upstream_gene_variant 0.35 bedaquiline
rifampicin
lpqB 3625060 c.-150G>T upstream_gene_variant 0.33 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>C upstream_gene_variant 0.31 bedaquiline
rifampicin
mtrB 3625087 c.1525_1527delGCCinsTG frameshift_variant&missense_variant 0.3 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625093 p.Glu507Asp missense_variant 0.32 bedaquiline
rifampicin
lpqB 3625099 c.-189C>G upstream_gene_variant 0.36 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 0.4 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.38 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.34 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 0.34 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 0.33 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 0.37 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.44 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.43 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 0.44 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625165 c.-255G>C upstream_gene_variant 0.45 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 0.51 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.49 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3625206 p.Ser470Ala missense_variant 0.41 bedaquiline
rifampicin
lpqB 3625207 c.-297C>T upstream_gene_variant 0.4 bedaquiline
rifampicin
lpqB 3625218 c.-308C>A upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.42 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625225 c.-315G>C upstream_gene_variant 0.39 bedaquiline
rifampicin
lpqB 3625240 c.-330T>C upstream_gene_variant 0.36 bedaquiline
rifampicin
lpqB 3625243 c.-333T>G upstream_gene_variant 0.3 bedaquiline
rifampicin
lpqB 3625246 c.-336G>C upstream_gene_variant 0.3 bedaquiline
rifampicin
lpqB 3625249 c.-339G>C upstream_gene_variant 0.3 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.36 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.26 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.25 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 0.26 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.26 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.23 bedaquiline
rifampicin
mtrB 3625497 c.1117T>C synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625510 c.-600T>C upstream_gene_variant 0.46 bedaquiline
rifampicin
lpqB 3625513 c.-603G>C upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625518 c.-608T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
lpqB 3625525 c.-615G>C upstream_gene_variant 0.57 bedaquiline
rifampicin
lpqB 3625528 c.-618G>T upstream_gene_variant 0.61 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.73 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.74 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.7 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625636 c.978C>G synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.68 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.66 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.66 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 0.58 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625749 c.-839C>T upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3625755 p.Ala287Thr missense_variant 0.7 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625777 c.-867C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3625797 p.Val273Met missense_variant 0.74 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625843 c.-933C>G upstream_gene_variant 0.74 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 0.64 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625900 c.-990G>C upstream_gene_variant 0.49 bedaquiline
rifampicin
lpqB 3625903 c.-993G>C upstream_gene_variant 0.45 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 0.4 bedaquiline
rifampicin
mtrB 3625923 c.691C>T synonymous_variant 0.28 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.23 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 0.22 bedaquiline
rifampicin
mtrB 3626083 c.531G>C synonymous_variant 0.19 bedaquiline
rifampicin
mtrB 3626092 c.522T>G synonymous_variant 0.36 bedaquiline
rifampicin
mtrB 3626095 p.Glu173Asp missense_variant 0.35 bedaquiline
rifampicin
mtrB 3626101 p.Gln171His missense_variant 0.35 bedaquiline
rifampicin
mtrB 3626107 c.507G>A synonymous_variant 0.39 bedaquiline
rifampicin
mtrB 3626110 c.504C>G synonymous_variant 0.39 bedaquiline
rifampicin
mtrB 3626122 c.490_492delGCCinsTA frameshift_variant&missense_variant 0.42 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626154 c.460C>T synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626155 c.457_459delGCGinsTC frameshift_variant&missense_variant 0.6 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626158 c.456C>T synonymous_variant 0.6 bedaquiline
rifampicin
mtrB 3626170 c.444T>C synonymous_variant 0.64 bedaquiline
rifampicin
mtrB 3626179 c.435A>G synonymous_variant 0.64 bedaquiline
rifampicin
mtrB 3626185 c.429T>G synonymous_variant 0.55 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626188 c.424_426delTCTinsAC frameshift_variant&missense_variant 0.46 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626194 c.420T>C synonymous_variant 0.44 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626317 c.297A>G synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626325 p.Thr97Ala missense_variant 0.26 bedaquiline
rifampicin
mtrB 3626332 c.282T>C synonymous_variant 0.26 bedaquiline
rifampicin
mtrB 3626338 c.276C>G synonymous_variant 0.27 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626347 c.265_267delAGCinsGT frameshift_variant&synonymous_variant 0.27 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626353 p.Thr87Lys missense_variant 0.28 bedaquiline
rifampicin
mtrB 3626359 c.255C>G synonymous_variant 0.28 bedaquiline
rifampicin
mtrB 3626362 c.252A>G synonymous_variant 0.28 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626377 p.Asp79Glu missense_variant 0.26 bedaquiline
rifampicin
mtrB 3626383 c.231G>C synonymous_variant 0.24 bedaquiline
rifampicin
mtrB 3626386 c.228G>C synonymous_variant 0.24 bedaquiline
rifampicin
mtrB 3626390 p.Arg75Lys missense_variant 0.24 bedaquiline
rifampicin
mtrB 3626562 p.Pro18Ser missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3626687 c.-74G>T upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 0.52 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.63 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.6 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.61 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.66 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrA 3626869 c.481C>T synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626876 c.-263A>G upstream_gene_variant 0.66 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.66 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.66 bedaquiline
rifampicin
mtrB 3626912 c.-299T>G upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 0.51 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.49 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.49 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 0.51 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.66 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrA 3627056 c.294C>T synonymous_variant 0.66 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627065 c.-452G>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627071 c.279G>T synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.63 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.66 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.66 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.66 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrA 3627146 c.204C>T synonymous_variant 0.66 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627167 c.-554T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.69 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.71 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.6 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrB 3627375 c.-762C>G upstream_gene_variant 0.29 bedaquiline
rifampicin
mtrB 3627377 c.-764G>C upstream_gene_variant 0.26 bedaquiline
rifampicin
mtrB 3627380 c.-767T>C upstream_gene_variant 0.27 bedaquiline
rifampicin
mtrA 3627837 c.-488G>C upstream_gene_variant 0.21 bedaquiline
rifampicin
mtrA 3627839 c.-490T>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrA 3627857 c.-508G>C upstream_gene_variant 0.4 bedaquiline
rifampicin
mtrA 3627860 c.-511G>C upstream_gene_variant 0.42 bedaquiline
rifampicin
mtrA 3627872 c.-523T>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrA 3627875 c.-526G>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrA 3627881 c.-532G>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrA 3627884 c.-535A>G upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrA 3627887 c.-538C>G upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrA 3627893 c.-544T>G upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrA 3627917 c.-568G>C upstream_gene_variant 0.49 bedaquiline
rifampicin
mtrA 3627920 c.-571A>G upstream_gene_variant 0.5 bedaquiline
rifampicin
fbiA 3640347 c.-196A>G upstream_gene_variant 0.21 clofazimine
pretomanid
delamanid
fbiA 3640350 c.-193C>T upstream_gene_variant 0.22 clofazimine
pretomanid
delamanid
fbiA 3640365 c.-178C>G upstream_gene_variant 0.25 clofazimine
pretomanid
delamanid
fbiA 3640372 c.-171A>G upstream_gene_variant 0.74 clofazimine
pretomanid
delamanid
fbiB 3640816 c.-719C>T upstream_gene_variant 0.27 clofazimine
pretomanid
delamanid
fbiA 3640820 p.Val93Ala missense_variant 0.3 clofazimine
pretomanid
delamanid
fbiB 3640827 c.-708T>C upstream_gene_variant 0.34 clofazimine
pretomanid
delamanid
fbiB 3640830 c.-705C>G upstream_gene_variant 0.37 clofazimine
pretomanid
delamanid
fbiB 3640839 c.-696C>G upstream_gene_variant 0.45 clofazimine
pretomanid
delamanid
fbiA 3640850 p.Glu103Gly missense_variant 0.44 clofazimine
pretomanid
delamanid
fbiB 3640857 c.-678G>C upstream_gene_variant 0.46 clofazimine
pretomanid
delamanid
fbiB 3640866 c.-669T>C upstream_gene_variant 0.54 clofazimine
pretomanid
delamanid
fbiA 3640871 p.Ala110Gly missense_variant 0.54 clofazimine
pretomanid
delamanid
fbiB 3640878 c.-657T>C upstream_gene_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3640899 c.-636G>C upstream_gene_variant 0.5 clofazimine
pretomanid
delamanid
fbiB 3640914 c.-621C>G upstream_gene_variant 0.41 clofazimine
pretomanid
delamanid
fbiA 3640930 p.Glu130Thr missense_variant 0.28 clofazimine
pretomanid
delamanid
fbiB 3640935 c.-600C>G upstream_gene_variant 0.28 clofazimine
pretomanid
delamanid
fbiB 3640938 c.-597A>G upstream_gene_variant 0.28 clofazimine
pretomanid
delamanid
fbiB 3640944 c.-591T>C upstream_gene_variant 0.28 clofazimine
pretomanid
delamanid
fbiB 3641622 p.Ser30Gly missense_variant 0.26 clofazimine
pretomanid
delamanid
fbiB 3641627 c.93C>G synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiB 3641642 c.108G>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiB 3641645 c.111A>G synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiB 3641654 c.120A>G synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiB 3641961 p.Thr143Glu missense_variant 0.28 clofazimine
pretomanid
delamanid
fbiB 3641972 c.438G>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiB 3641993 c.459A>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fbiB 3642096 p.Val188Leu missense_variant 0.27 clofazimine
pretomanid
delamanid
fbiB 3642113 c.579A>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiB 3642114 p.Val194Ile missense_variant 0.25 clofazimine Uncertain significance
pretomanid
delamanid
fbiB 3642152 c.618A>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiB 3642169 p.Thr212Met missense_variant 0.28 clofazimine
pretomanid
delamanid
fbiB 3642560 c.1026T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiB 3642566 c.1032A>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiB 3642587 p.Met351Ile missense_variant 0.3 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>T synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiB 3642609 c.1075_1076delAGinsTC synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiB 3642614 c.1080C>T synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiB 3642617 c.1083C>G synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642659 c.1125C>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>G synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiB 3642731 c.1197C>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiB 3642758 c.1224C>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiB 3642763 p.Asp410Ala missense_variant 0.42 clofazimine
pretomanid
delamanid
fbiB 3642767 c.1233G>A synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiB 3642770 c.1236G>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiB 3642779 c.1245A>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiB 3642781 p.Val416Ala missense_variant 0.37 clofazimine
pretomanid
delamanid
fbiB 3642809 c.1275G>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
rpoA 3877482 c.1026C>G synonymous_variant 0.32 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 0.45 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.46 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.49 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.52 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.68 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.69 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.71 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.7 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.73 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.72 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.68 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.69 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.68 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.69 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.69 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.72 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.72 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.71 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.7 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.68 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.63 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.65 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.62 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.62 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 0.6 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.58 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.57 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.56 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.59 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.61 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.63 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878094 c.414C>G synonymous_variant 0.57 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.5 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.52 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.57 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.56 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.58 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.58 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.62 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.6 rifampicin
rpoA 3878181 c.327C>T synonymous_variant 0.65 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.65 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.71 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.74 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.76 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.79 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.72 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.66 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878340 c.168C>T synonymous_variant 0.64 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 0.69 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.73 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.74 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.7 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.71 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.72 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.74 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.75 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.77 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.72 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.65 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.56 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.55 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.57 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.55 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.42 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 0.63 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 0.64 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.67 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.68 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.7 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.69 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.71 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.73 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.73 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.68 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.66 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.69 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.69 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.7 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.68 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.68 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.7 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.71 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.73 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.71 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.71 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.73 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.73 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 0.71 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.69 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.71 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.72 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.71 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.73 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.72 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.72 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.72 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.71 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.71 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.69 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.7 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.71 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.66 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.49 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.43 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.39 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.4 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.58 delamanid
pretomanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.49 delamanid
pretomanid
ddn 3986646 c.-198_-196delCTCinsTG upstream_gene_variant 0.49 delamanid
pretomanid
ddn 3986665 c.-179G>C upstream_gene_variant 0.36 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.35 delamanid
pretomanid
ddn 3986672 c.-172G>A upstream_gene_variant 0.36 delamanid
pretomanid
ddn 3986673 c.-171C>T upstream_gene_variant 0.37 delamanid
pretomanid
ddn 3986681 c.-163C>G upstream_gene_variant 0.34 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.32 delamanid
pretomanid
ddn 3986696 c.-148G>C upstream_gene_variant 0.34 delamanid
pretomanid
clpC1 4038206 c.2499C>A synonymous_variant 0.22 pyrazinamide
clpC1 4038212 c.2493T>C synonymous_variant 0.25 pyrazinamide
clpC1 4038239 c.2466T>C synonymous_variant 0.39 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 0.51 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.53 pyrazinamide
clpC1 4038272 c.2431_2433delGGTinsAC frameshift_variant&missense_variant 0.53 pyrazinamide
clpC1 4038275 c.2430A>G synonymous_variant 0.53 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.56 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.6 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.58 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.57 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.56 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.54 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.55 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.64 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.64 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.64 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.64 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.63 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.62 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.63 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.62 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.48 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.47 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.42 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.41 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.47 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.47 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.38 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.38 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.41 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.39 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.5 pyrazinamide
clpC1 4038530 c.2175G>A synonymous_variant 0.65 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.72 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.72 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.74 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.7 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.67 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.67 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.69 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.58 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.48 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.44 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.45 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.47 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.52 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.56 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.56 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.56 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.62 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.66 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.65 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.76 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.74 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.72 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.72 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.7 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.68 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.66 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.7 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.65 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.64 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.63 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.63 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.63 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.64 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>T synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.62 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.6 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.59 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.49 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.49 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.57 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.57 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.58 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.59 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.6 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.63 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.79 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.6 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.6 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.6 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.75 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039718 c.987C>A synonymous_variant 0.61 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.66 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.66 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.67 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.66 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.62 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.62 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.75 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.75 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.74 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.74 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.72 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.77 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.61 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.66 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.53 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.53 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.52 pyrazinamide
clpC1 4040210 c.495G>C synonymous_variant 0.51 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.53 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.62 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.64 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.71 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.74 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.74 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.56 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.62 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.59 pyrazinamide
clpC1 4040321 c.384C>T synonymous_variant 0.57 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.48 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.39 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.36 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.36 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.21 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.48 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.49 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.52 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.64 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.67 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.71 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.68 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.56 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.55 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.56 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.45 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.42 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040644 c.61A>C synonymous_variant 0.48 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.48 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 0.42 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.43 pyrazinamide
clpC1 4040706 c.-4_-3delAC upstream_gene_variant 0.39 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.37 pyrazinamide
clpC1 4040987 c.-283G>A upstream_gene_variant 0.33 pyrazinamide
clpC1 4040990 c.-286G>C upstream_gene_variant 0.32 pyrazinamide
clpC1 4040997 c.-293A>T upstream_gene_variant 0.36 pyrazinamide
clpC1 4040999 c.-295A>G upstream_gene_variant 0.37 pyrazinamide
panD 4043865 c.415_417delGGAinsCG frameshift_variant&missense_variant 0.4 pyrazinamide Uncertain significance
panD 4043872 p.Gly137Val missense_variant 0.39 pyrazinamide Uncertain significance
panD 4043876 p.Leu136Ile missense_variant 0.38 pyrazinamide
panD 4043883 c.399C>T synonymous_variant 0.42 pyrazinamide
panD 4043886 c.396A>G synonymous_variant 0.44 pyrazinamide
panD 4043896 p.Gly129Ala missense_variant 0.43 pyrazinamide
panD 4043903 p.Asn127Asp missense_variant 0.39 pyrazinamide
panD 4043913 c.369T>C synonymous_variant 0.36 pyrazinamide
panD 4043916 c.366A>G synonymous_variant 0.35 pyrazinamide
panD 4043922 c.360T>C synonymous_variant 0.27 pyrazinamide
panD 4044072 c.210C>G synonymous_variant 0.34 pyrazinamide
panD 4044075 c.207T>C synonymous_variant 0.34 pyrazinamide
panD 4044081 c.201T>C synonymous_variant 0.39 pyrazinamide
panD 4044084 c.198T>C synonymous_variant 0.39 pyrazinamide
panD 4044105 c.177G>C synonymous_variant 0.44 pyrazinamide
panD 4044117 c.165G>C synonymous_variant 0.42 pyrazinamide
panD 4044120 c.162A>C synonymous_variant 0.42 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.43 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 0.43 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 0.51 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.38 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.27 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.34 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.36 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 0.41 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.43 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.43 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.44 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.44 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.45 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.38 pyrazinamide
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 0.31 pyrazinamide
panD 4044823 c.-542G>C upstream_gene_variant 0.29 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.28 pyrazinamide
panD 4044848 c.-567T>A upstream_gene_variant 0.21 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 0.26 pyrazinamide
panD 4044926 c.-645C>A upstream_gene_variant 0.33 pyrazinamide
panD 4044929 c.-648G>C upstream_gene_variant 0.33 pyrazinamide
panD 4044935 c.-655_-654delAAinsTG upstream_gene_variant 0.33 pyrazinamide
panD 4044941 c.-660G>C upstream_gene_variant 0.36 pyrazinamide
panD 4044954 c.-674_-673delCCinsAT upstream_gene_variant 0.44 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.52 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 0.53 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.55 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.55 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.55 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 0.56 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.56 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.59 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.6 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.54 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.53 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.52 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.49 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.45 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 0.39 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.39 pyrazinamide
panD 4045105 c.-824T>C upstream_gene_variant 0.36 pyrazinamide
glpK 4138418 c.1338T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138424 c.1332T>C synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138460 c.1296C>T synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>T synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138475 c.1281C>T synonymous_variant 0.28 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138478 c.1278T>C synonymous_variant 0.28 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>A synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138565 c.1191G>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>A synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 0.31 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138643 c.1113A>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 0.31 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.41 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138695 p.Pro354Asp missense_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138802 c.954G>A synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138805 c.951C>T synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138822 p.Asn312Asp missense_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138902 p.Asn285Ser missense_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139104 c.652T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139107 c.649C>T synonymous_variant 0.27 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139126 c.630G>C synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139135 c.619_621delGATinsAC frameshift_variant&synonymous_variant 0.51 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139143 c.613T>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139195 c.561G>T synonymous_variant 0.56 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139198 c.558C>G synonymous_variant 0.53 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139207 c.549T>C synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139231 c.525A>C synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139243 c.513A>G synonymous_variant 0.24 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139573 c.183C>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 0.42 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139597 c.159C>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Gln missense_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139615 c.141G>A synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139651 c.103_105delCACinsGG frameshift_variant&missense_variant 0.5 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139675 c.81C>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139684 c.72C>G synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139687 c.69C>G synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139699 c.57C>T synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239125 c.-738C>G upstream_gene_variant 0.37 ethambutol
embC 4239129 c.-734C>T upstream_gene_variant 0.37 ethambutol
embC 4239140 c.-723G>C upstream_gene_variant 0.38 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.38 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 0.37 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 0.38 ethambutol
embC 4239156 c.-707_-706delACinsGT upstream_gene_variant 0.38 ethambutol
embC 4239161 c.-702A>T upstream_gene_variant 0.37 ethambutol
embC 4239165 c.-698C>T upstream_gene_variant 0.34 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 0.33 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 0.32 ethambutol
embC 4239209 c.-654G>C upstream_gene_variant 0.21 ethambutol
embC 4239336 c.-527_-525delTTGinsCA upstream_gene_variant 0.36 ethambutol
embC 4239341 c.-522G>C upstream_gene_variant 0.39 ethambutol
embC 4239344 c.-519G>C upstream_gene_variant 0.4 ethambutol
embC 4239350 c.-513G>C upstream_gene_variant 0.41 ethambutol
embC 4239378 c.-485T>A upstream_gene_variant 0.46 ethambutol
embC 4239383 c.-480C>G upstream_gene_variant 0.45 ethambutol
embC 4239401 c.-462A>G upstream_gene_variant 0.5 ethambutol
embC 4239408 c.-455G>A upstream_gene_variant 0.41 ethambutol Uncertain significance
embC 4239411 c.-452T>A upstream_gene_variant 0.34 ethambutol
embC 4239416 c.-447G>A upstream_gene_variant 0.23 ethambutol Uncertain significance
embC 4240123 c.261C>G synonymous_variant 0.31 ethambutol
embC 4240126 c.264C>T synonymous_variant 0.31 ethambutol
embC 4240141 c.279A>G synonymous_variant 0.24 ethambutol
embC 4240145 p.Ala95Thr missense_variant 0.23 ethambutol Uncertain significance
embC 4240178 c.316T>C synonymous_variant 0.26 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.29 ethambutol
embC 4240204 c.342T>C synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embC 4240258 c.396T>G synonymous_variant 0.29 ethambutol
embC 4240444 c.582C>G synonymous_variant 0.22 ethambutol
embC 4240459 c.597G>C synonymous_variant 0.36 ethambutol
embC 4240462 c.600G>C synonymous_variant 0.37 ethambutol
embC 4240471 c.609C>T synonymous_variant 0.36 ethambutol
embC 4240474 c.612G>C synonymous_variant 0.35 ethambutol
embC 4240475 p.Ala205Ser missense_variant 0.35 ethambutol Uncertain significance
embC 4240484 p.Ala208Thr missense_variant 0.38 ethambutol
embC 4240489 c.627A>G synonymous_variant 0.38 ethambutol
embC 4240492 c.630G>C synonymous_variant 0.41 ethambutol
embC 4240495 c.633T>G synonymous_variant 0.39 ethambutol
embC 4240505 p.Ser215Ala missense_variant 0.42 ethambutol Uncertain significance
embC 4240512 p.Ser217Thr missense_variant 0.42 ethambutol
embC 4240516 c.654G>C synonymous_variant 0.41 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.43 ethambutol
embC 4240543 c.681G>C synonymous_variant 0.26 ethambutol
embC 4240630 c.768C>A synonymous_variant 0.24 ethambutol
embC 4240632 p.Met257Thr missense_variant 0.24 ethambutol
embC 4240642 c.780G>C synonymous_variant 0.41 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.48 ethambutol
embC 4240654 c.792C>G synonymous_variant 0.56 ethambutol Not assoc w R - Interim
embC 4240660 c.798C>G synonymous_variant 0.57 ethambutol
embC 4240669 c.807G>C synonymous_variant 0.6 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.61 ethambutol Not assoc w R
embC 4240677 p.Gly272Ala missense_variant 0.62 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.7 ethambutol
embC 4240693 c.831T>G synonymous_variant 0.73 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.68 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.66 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.65 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.64 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.63 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.63 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.54 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.5 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.49 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.47 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.47 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.47 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.41 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.41 ethambutol
embC 4240903 c.1041C>G synonymous_variant 0.4 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.4 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.36 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.31 ethambutol
embC 4241002 c.1140G>C synonymous_variant 0.3 ethambutol
embC 4241013 p.Met384Thr missense_variant 0.36 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.35 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.4 ethambutol
embC 4241032 c.1170G>C synonymous_variant 0.47 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.55 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.58 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.58 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.63 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.68 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.68 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.7 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.63 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.63 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.61 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.61 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.61 ethambutol
embC 4241179 c.1317G>A synonymous_variant 0.58 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.45 ethambutol
embC 4241206 c.1344G>C synonymous_variant 0.44 ethambutol Not assoc w R - Interim
embC 4241218 c.1356G>C synonymous_variant 0.38 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.32 ethambutol
embC 4241233 c.1371G>C synonymous_variant 0.28 ethambutol
embC 4241351 p.Ile497Val missense_variant 0.19 ethambutol
embC 4241361 p.Asn500Thr missense_variant 0.23 ethambutol
embC 4241363 c.1501_1503delCTCinsAG frameshift_variant&missense_variant 0.23 ethambutol
embC 4241374 c.1512T>G synonymous_variant 0.3 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.32 ethambutol
embC 4241383 c.1521G>C synonymous_variant 0.35 ethambutol Not assoc w R - Interim
embC 4241394 p.Lys511Ser missense_variant 0.4 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.63 ethambutol
embC 4241453 p.Ile531Val missense_variant 0.66 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.61 ethambutol
embC 4241480 c.1618T>C synonymous_variant 0.61 ethambutol
embC 4241488 c.1626G>C synonymous_variant 0.62 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.6 ethambutol
embC 4241500 c.1638A>C synonymous_variant 0.6 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.6 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.6 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.6 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>G synonymous_variant 0.62 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.56 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embC 4241545 c.1683T>C synonymous_variant 0.53 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.54 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.56 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.51 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.49 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.52 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.53 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.54 ethambutol
embC 4241591 p.Leu577Val missense_variant 0.57 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.53 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.52 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.48 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.46 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.42 ethambutol
embC 4241648 c.1786_1788delTTGinsCC frameshift_variant&missense_variant 0.39 ethambutol
embC 4241657 p.Ser599Pro missense_variant 0.33 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.26 ethambutol
embC 4241671 c.1809T>C synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embC 4241713 c.1851G>C synonymous_variant 0.23 ethambutol
embC 4241719 c.1857G>C synonymous_variant 0.31 ethambutol
embC 4241727 p.Phe622Tyr missense_variant 0.38 ethambutol
embC 4241741 c.1879_1881delGTCinsCG frameshift_variant&missense_variant 0.38 ethambutol
embC 4241747 p.Val629Leu missense_variant 0.36 ethambutol
embC 4241750 p.Leu630Val missense_variant 0.35 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.35 ethambutol
embC 4241770 c.1908T>C synonymous_variant 0.36 ethambutol Not assoc w R - Interim
embC 4241791 c.1929G>C synonymous_variant 0.34 ethambutol
embC 4241794 c.1932C>G synonymous_variant 0.35 ethambutol
embC 4241797 c.1935C>T synonymous_variant 0.32 ethambutol
embC 4241809 c.1947A>C synonymous_variant 0.23 ethambutol
embA 4242589 c.-644A>G upstream_gene_variant 0.23 ethambutol
embC 4242643 c.2781C>T synonymous_variant 0.88 ethambutol Not assoc w R
embC 4242689 c.2827_2829delGTCinsAT frameshift_variant&missense_variant 0.19 ethambutol
embC 4242710 c.2848_2850delCAGinsGA frameshift_variant&missense_variant 0.28 ethambutol
embC 4242715 c.2853T>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
embA 4242742 c.-491C>G upstream_gene_variant 0.38 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.39 ethambutol
embA 4242754 c.-479G>C upstream_gene_variant 0.4 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.41 ethambutol
embA 4242772 c.-461G>C upstream_gene_variant 0.4 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.38 ethambutol
embC 4242791 c.2929_2931delGCAinsTC frameshift_variant&missense_variant 0.26 ethambutol
embA 4242796 c.-437G>C upstream_gene_variant 0.25 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.26 ethambutol
embA 4242802 c.-431G>C upstream_gene_variant 0.28 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.29 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.31 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.35 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 0.35 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.36 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embA 4242892 c.-341G>C upstream_gene_variant 0.43 ethambutol
embA 4242901 c.-332G>C upstream_gene_variant 0.4 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.32 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embA 4242931 c.-302G>C upstream_gene_variant 0.27 ethambutol
embA 4243460 c.228C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244507 c.1275G>T synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embA 4244516 c.1284G>C synonymous_variant 0.25 ethambutol
embA 4244517 p.Leu429Val missense_variant 0.26 ethambutol
embA 4244523 p.Pro431Ala missense_variant 0.37 ethambutol
embA 4244534 c.1302T>C synonymous_variant 0.36 ethambutol
embA 4244537 c.1305T>G synonymous_variant 0.36 ethambutol
embA 4244543 c.1311C>G synonymous_variant 0.37 ethambutol
embA 4244547 p.Ile439Val missense_variant 0.38 ethambutol
embA 4244557 p.Arg442Thr missense_variant 0.38 ethambutol
embA 4244582 c.1350T>C synonymous_variant 0.4 ethambutol
embA 4244585 c.1353A>G synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embA 4244957 c.1725C>T synonymous_variant 0.22 ethambutol
embA 4245041 c.1809C>G synonymous_variant 0.33 ethambutol
embA 4245044 c.1812G>C synonymous_variant 0.36 ethambutol
embA 4245053 c.1821G>C synonymous_variant 0.49 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.58 ethambutol
embA 4245083 c.1851A>C synonymous_variant 0.72 ethambutol
embA 4245089 c.1857G>C synonymous_variant 0.75 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.77 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.73 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.7 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.69 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.69 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.66 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.64 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.63 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.61 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.65 ethambutol
embA 4245222 c.1990_1992delTATinsCG frameshift_variant&missense_variant 0.64 ethambutol Uncertain significance
embA 4245248 c.2016G>C synonymous_variant 0.57 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.54 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embA 4245282 p.Ile684Val missense_variant 0.35 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.34 ethambutol
embA 4245290 c.2058C>G synonymous_variant 0.3 ethambutol
embA 4245293 c.2061T>G synonymous_variant 0.29 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.29 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.28 ethambutol
embB 4245659 c.-855C>G upstream_gene_variant 0.22 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.41 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.47 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.56 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.6 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.62 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.65 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.65 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.63 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.63 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.64 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.63 ethambutol
embA 4245785 c.2553G>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 0.54 ethambutol Uncertain significance
embB 4245812 c.-702G>C upstream_gene_variant 0.53 ethambutol
embA 4245813 c.2581_2583delCCCinsGG frameshift_variant&missense_variant 0.53 ethambutol Uncertain significance
embA 4245820 p.Ser863Thr missense_variant 0.54 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 0.52 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 0.6 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 0.61 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 0.62 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.63 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.63 ethambutol
embA 4245885 p.Asp885Thr missense_variant 0.44 ethambutol
embA 4245892 p.Ile887Thr missense_variant 0.45 ethambutol Uncertain significance
embA 4245899 c.2667C>G synonymous_variant 0.44 ethambutol Not assoc w R - Interim
embB 4245902 c.-612G>A upstream_gene_variant 0.43 ethambutol
embB 4245905 c.-609C>G upstream_gene_variant 0.43 ethambutol
embB 4245911 c.-603A>G upstream_gene_variant 0.43 ethambutol
embB 4245917 c.-597G>A upstream_gene_variant 0.43 ethambutol
embA 4245930 p.Gly900Arg missense_variant 0.33 ethambutol
embB 4246022 c.-492C>G upstream_gene_variant 0.24 ethambutol
embB 4246040 c.-474C>G upstream_gene_variant 0.38 ethambutol
embA 4246041 p.Asp937Asn missense_variant 0.38 ethambutol
embA 4246055 c.2823T>C synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embB 4246064 c.-450T>C upstream_gene_variant 0.4 ethambutol
embA 4246080 c.2848_2850delCCTinsTC frameshift_variant&missense_variant 0.32 ethambutol Uncertain significance
embA 4246088 c.2856A>G synonymous_variant 0.35 ethambutol Not assoc w R
embB 4246097 c.-417C>G upstream_gene_variant 0.41 ethambutol
embA 4246103 c.2871C>G synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4246109 c.-405C>G upstream_gene_variant 0.39 ethambutol
embB 4246115 c.-399T>G upstream_gene_variant 0.34 ethambutol
embB 4246157 c.-357A>G upstream_gene_variant 0.25 ethambutol
embA 4246164 c.2932T>C synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embB 4246184 c.-330A>C upstream_gene_variant 0.41 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 0.46 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.5 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.56 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.53 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.53 ethambutol
embA 4246227 p.Ile999Val missense_variant 0.54 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.55 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.63 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.61 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.6 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.63 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.62 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.56 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.57 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.6 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.62 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.64 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.61 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.57 ethambutol Uncertain significance
embB 4246367 c.-147C>T upstream_gene_variant 0.53 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.48 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.46 ethambutol
embA 4246379 c.3147C>T synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embB 4246400 c.-114G>C upstream_gene_variant 0.44 ethambutol
embA 4246413 p.His1061Phe missense_variant 0.26 ethambutol
embA 4246419 c.3187C>T synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embB 4247050 c.537C>G synonymous_variant 0.27 ethambutol
embB 4247059 c.546C>A synonymous_variant 0.27 ethambutol
embB 4247068 c.555T>C synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embB 4247074 c.561G>T synonymous_variant 0.31 ethambutol
embB 4247095 c.582G>T synonymous_variant 0.29 ethambutol
embB 4247098 c.585C>G synonymous_variant 0.29 ethambutol
embB 4247101 c.588G>C synonymous_variant 0.28 ethambutol
embB 4247105 p.Pro198Ala missense_variant 0.27 ethambutol
embB 4247110 c.597G>C synonymous_variant 0.28 ethambutol
embB 4247111 c.598C>T synonymous_variant 0.28 ethambutol
embB 4247114 p.Ala201Thr missense_variant 0.27 ethambutol Uncertain significance
embB 4247117 c.604_606delGTCinsCG frameshift_variant&missense_variant 0.28 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.26 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.27 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.33 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.47 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.5 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.51 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.51 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.56 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.68 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.69 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.72 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.71 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.68 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.66 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.6 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.5 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.46 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.41 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.38 ethambutol
embB 4247588 c.1075_1077delCTAinsAC frameshift_variant&missense_variant 0.38 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.45 ethambutol
embB 4247611 c.1098G>T synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embB 4247614 c.1101T>C synonymous_variant 0.44 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.37 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.37 ethambutol
embB 4247638 c.1125G>T synonymous_variant 0.39 ethambutol
embB 4247646 p.Glu378Ala missense_variant 0.3 ethambutol Not assoc w R
embB 4247656 c.1143A>G synonymous_variant 0.3 ethambutol
embB 4247659 c.1146C>G synonymous_variant 0.31 ethambutol
embB 4247662 c.1149C>G synonymous_variant 0.31 ethambutol
embB 4247683 c.1170C>G synonymous_variant 0.38 ethambutol
embB 4247692 c.1179C>G synonymous_variant 0.3 ethambutol
embB 4247716 c.1203C>T synonymous_variant 0.38 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.39 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.39 ethambutol
embB 4247729 p.Gly406Pro missense_variant 0.39 ethambutol
embB 4247746 c.1233C>T synonymous_variant 0.5 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.53 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.54 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.57 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.56 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.57 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.58 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.61 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 0.63 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.65 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.61 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.6 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.62 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.6 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.61 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.59 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.58 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.59 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.57 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.55 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.52 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.49 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.53 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.55 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.5 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.51 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.57 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.56 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.56 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.56 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.64 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.63 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.67 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.63 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.63 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.63 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.68 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.69 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.62 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.62 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.61 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.62 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.68 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.65 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.65 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.65 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.57 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.52 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.52 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.5 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.5 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.51 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.54 ethambutol
embB 4248382 c.1869C>G synonymous_variant 0.53 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.52 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 0.39 ethambutol
embB 4248410 c.1897_1899delTTCinsCG frameshift_variant&missense_variant 0.38 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.38 ethambutol
embB 4248425 c.1912T>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 0.38 ethambutol
embB 4248432 p.Trp640Phe missense_variant 0.38 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.55 ethambutol
embB 4248472 c.1959T>C synonymous_variant 0.47 ethambutol
embB 4248475 c.1962G>C synonymous_variant 0.47 ethambutol
embB 4248488 c.1975_1977delGCGinsAC frameshift_variant&missense_variant 0.35 ethambutol
embB 4248504 p.Asp664Gly missense_variant 0.37 ethambutol Uncertain significance
embB 4248508 c.1995G>A synonymous_variant 0.35 ethambutol Not assoc w R - Interim
embB 4248512 c.1999_2001delACAinsTG frameshift_variant&stop_gained 0.35 ethambutol
embB 4248535 c.2022C>G synonymous_variant 0.23 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.35 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.42 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.44 ethambutol
embB 4249384 c.2871G>T synonymous_variant 0.45 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.6 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.6 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.6 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.61 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.61 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.63 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.58 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.6 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.56 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.56 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.55 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.54 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.54 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.51 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.5 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.46 ethambutol
embB 4249568 p.Ser1019Thr missense_variant 0.44 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.4 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.32 ethambutol
aftB 4267200 p.Trp546Val missense_variant 0.25 ethambutol
aftB 4267214 c.1623A>C synonymous_variant 0.26 ethambutol
aftB 4267241 c.1596G>C synonymous_variant 0.25 ethambutol
aftB 4267244 c.1593T>C synonymous_variant 0.26 ethambutol
aftB 4267256 c.1581C>G synonymous_variant 0.28 ethambutol
aftB 4267262 c.1575T>C synonymous_variant 0.25 ethambutol
aftB 4267266 p.Ala524Gly missense_variant 0.23 ethambutol
aftB 4267268 c.1569T>C synonymous_variant 0.23 ethambutol
aftB 4267274 c.1563G>C synonymous_variant 0.25 ethambutol
aftB 4267574 c.1263G>A synonymous_variant 0.29 ethambutol
aftB 4267580 c.1257G>T synonymous_variant 0.31 ethambutol
aftB 4267604 c.1233C>G synonymous_variant 0.4 ethambutol
aftB 4267607 c.1230G>A synonymous_variant 0.4 ethambutol
aftB 4267622 c.1215G>C synonymous_variant 0.34 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.35 ethambutol
aftB 4267628 c.1209C>G synonymous_variant 0.35 ethambutol
aftB 4267634 p.Arg401His missense_variant 0.35 ethambutol
aftB 4267647 p.Asp397Gly missense_variant 0.71 ethambutol Not assoc w R
aftB 4267649 c.1188T>C synonymous_variant 0.29 ethambutol Not assoc w R - Interim
aftB 4268096 c.741C>G synonymous_variant 0.22 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.22 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.27 ethambutol Not assoc w R - Interim
aftB 4268117 c.720G>C synonymous_variant 0.31 ethambutol
aftB 4268123 c.712_714delAGTinsGC frameshift_variant&synonymous_variant 0.32 ethambutol Uncertain significance
aftB 4268129 c.708T>G synonymous_variant 0.37 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.41 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.44 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.46 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.42 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.4 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
aftB 4268182 p.Phe219Leu missense_variant 0.37 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.37 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.36 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.37 ethambutol
aftB 4268213 c.624T>G synonymous_variant 0.36 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.32 ethambutol
aftB 4268236 c.601T>C synonymous_variant 0.21 ethambutol
aftB 4268386 c.451T>C synonymous_variant 0.28 ethambutol
aftB 4268393 c.444G>C synonymous_variant 0.28 ethambutol Not assoc w R - Interim
aftB 4268396 c.441T>C synonymous_variant 0.28 ethambutol
aftB 4268404 c.433T>C synonymous_variant 0.29 ethambutol
aftB 4268406 p.Val144Ala missense_variant 0.29 ethambutol
aftB 4268410 c.427C>T synonymous_variant 0.29 ethambutol Not assoc w R - Interim
aftB 4268411 c.426G>T synonymous_variant 0.28 ethambutol
aftB 4268417 c.420G>A synonymous_variant 0.28 ethambutol
aftB 4268426 c.411C>G synonymous_variant 0.29 ethambutol
aftB 4268444 c.393C>G synonymous_variant 0.28 ethambutol Not assoc w R - Interim
aftB 4268450 c.387A>G synonymous_variant 0.26 ethambutol Not assoc w R - Interim
aftB 4268455 p.Val128Leu missense_variant 0.25 ethambutol
ubiA 4268969 p.Leu289Val missense_variant 0.21 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 0.38 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 0.42 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.43 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.48 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.53 ethambutol
ubiA 4269027 c.807C>T synonymous_variant 0.48 ethambutol Not assoc w R - Interim
aftB 4269033 c.-197T>C upstream_gene_variant 0.49 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.51 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.5 ethambutol
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 0.36 ethambutol
aftB 4269081 c.-245G>C upstream_gene_variant 0.32 ethambutol
aftB 4269084 c.-248G>C upstream_gene_variant 0.31 ethambutol
aftB 4269159 c.-323G>C upstream_gene_variant 0.28 ethambutol
ubiA 4269164 p.Leu224Met missense_variant 0.29 ethambutol
aftB 4269165 c.-329G>C upstream_gene_variant 0.3 ethambutol
aftB 4269179 c.-343C>A upstream_gene_variant 0.46 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.47 ethambutol
aftB 4269186 c.-350C>G upstream_gene_variant 0.47 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.52 ethambutol
aftB 4269206 c.-370C>T upstream_gene_variant 0.51 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.53 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
aftB 4269242 c.-406C>T upstream_gene_variant 0.49 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.48 ethambutol
aftB 4269249 c.-413G>A upstream_gene_variant 0.44 ethambutol
aftB 4269258 c.-422C>T upstream_gene_variant 0.45 ethambutol
aftB 4269342 c.-506G>C upstream_gene_variant 0.24 ethambutol
ubiA 4269357 p.Ile159Met missense_variant 0.23 ethambutol Uncertain significance
aftB 4269372 c.-536G>A upstream_gene_variant 0.22 ethambutol
ubiA 4269380 p.Val152Ile missense_variant 0.22 ethambutol
ubiA 4269387 p.Glu149Asp missense_variant 0.22 ethambutol Not assoc w R
aftB 4269390 c.-554G>T upstream_gene_variant 0.22 ethambutol
aftB 4269402 c.-566T>C upstream_gene_variant 0.25 ethambutol
aftB 4269405 c.-569G>A upstream_gene_variant 0.25 ethambutol
aftB 4269411 c.-575T>A upstream_gene_variant 0.24 ethambutol
aftB 4269414 c.-578T>C upstream_gene_variant 0.25 ethambutol
aftB 4269420 c.-584T>C upstream_gene_variant 0.25 ethambutol
ubiA 4269521 p.Val105Leu missense_variant 0.28 ethambutol
ubiA 4269524 p.Thr104Ala missense_variant 0.3 ethambutol Uncertain significance
aftB 4269528 c.-692G>C upstream_gene_variant 0.34 ethambutol
aftB 4269549 c.-713C>G upstream_gene_variant 0.38 ethambutol
ubiA 4269552 c.282C>G synonymous_variant 0.37 ethambutol Not assoc w R - Interim
aftB 4269555 c.-719C>G upstream_gene_variant 0.37 ethambutol
aftB 4269564 c.-728G>C upstream_gene_variant 0.43 ethambutol
aftB 4269573 c.-737A>G upstream_gene_variant 0.42 ethambutol
ubiA 4269585 c.249G>A synonymous_variant 0.41 ethambutol Not assoc w R - Interim
aftB 4269588 c.-752G>C upstream_gene_variant 0.39 ethambutol
aftB 4269594 c.-758A>C upstream_gene_variant 0.39 ethambutol
ubiA 4269606 c.228T>C synonymous_variant 0.33 ethambutol Not assoc w R
aftB 4269612 c.-776T>C upstream_gene_variant 0.3 ethambutol
ethR 4327396 c.-153A>G upstream_gene_variant 1.0 ethionamide
ethA 4327399 p.Asp25Glu missense_variant 1.0 ethionamide
ethR 4327423 c.-126G>C upstream_gene_variant 1.0 ethionamide
ethR 4327435 c.-114T>G upstream_gene_variant 1.0 ethionamide
ethR 4327438 c.-111A>G upstream_gene_variant 1.0 ethionamide
ethA 4327452 p.Val8Leu missense_variant 1.0 ethionamide
ethR 4327453 c.-96A>G upstream_gene_variant 1.0 ethionamide
ethR 4327459 c.-90G>A upstream_gene_variant 1.0 ethionamide
ethR 4327468 c.-81G>A upstream_gene_variant 1.0 ethionamide
ethA 4328449 c.-976C>G upstream_gene_variant 0.97 ethionamide
ethA 4328463 c.-990G>C upstream_gene_variant 0.98 ethionamide
ethA 4328467 c.-994G>T upstream_gene_variant 0.98 ethionamide
ethA 4328470 c.-998_-997delAGinsGC upstream_gene_variant 0.95 ethionamide
whiB6 4338338 p.Cys62Arg missense_variant 1.0 capreomycin Uncertain significance
amikacin Uncertain significance
kanamycin Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Not assoc w R