Run ID: SRR3742657
Sample name:
Date: 2024-04-16T03:40:34.793117
Number of reads: 3298004
Percentage reads mapped: 40.25
Median coverage: 75.0
Strain: La3;M.canetti;lineage2.2.1
Spoligotype:
Drug-resistance: Pre-XDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage2 | East-Asian | RD105 | 0.95 |
lineage6.2.2 | West-Africa 2 | RD702 | 0.05 |
La1.2.BCG | M.bovis | None | 0.25 |
lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 0.92 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 0.98 |
lineage6.2.3 | West-Africa 2 | RD702 | 0.19 |
La1.7.1 | M.bovis | None | 0.08 |
La3 | M.orygis | None | 0.23 |
M.canetti | M.canetti | None | 0.06 |
lineage6.2.1 | West-Africa 2 | RD702 | 0.09 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Asp435Val | Assoc w R | |
isoniazid | inhA | c.-777C>T | Assoc w R | Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) |
katG | c.-2237_*6541del | Assoc w R | High-level resistance | |
ahpC | c.-81C>T | Uncertain significance | Mutation from literature | |
ethambutol | embA | c.-16C>T | Uncertain significance | Mutation from literature |
embB | p.His312Arg | Mutation from literature | ||
p.Tyr384Asn | Mutation from literature | |||
p.Ala388Gly | Mutation from literature | |||
p.Asn399Asp | Mutation from literature | |||
pyrazinamide | pncA | p.Val180Gly | Assoc w R | |
panD | p.Val138Ala | Mutation from literature | ||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
n.514A>C | Assoc w R | |||
fluoroquinolones | ||||
moxifloxacin | gyrA | p.Ala90Val | Assoc w R | Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) |
p.Ser91Pro | Assoc w R | Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) | ||
ofloxacin | ||||
levofloxacin | gyrA | p.Ala90Val | Assoc w R | |
p.Ser91Pro | Assoc w R | |||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | rrs | n.1402C>T | Assoc w R - Interim | |
capreomycin | rrs | n.1402C>T | Assoc w R | |
tlyA | c.319_321delCACinsGA | Assoc w R | ||
c.376_378delCCTinsGG | Assoc w R | |||
kanamycin | rrs | n.1402C>T | Assoc w R - Interim | |
cycloserine | ||||
ethionamide | inhA | c.-777C>T | Assoc w R | Alias fabG1_c.-15C>T |
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.202_204delCTGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.412_414delCTAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiC | c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.1024_1026delGAAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiA | c.358_360delCAGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
gyrA | 7570 | p.Ala90Val | missense_variant | 0.71 | levofloxacin | Assoc w R | |
moxifloxacin | Assoc w R | Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) | |||||
gyrA | 7572 | p.Ser91Pro | missense_variant | 0.71 | levofloxacin | Assoc w R | |
moxifloxacin | Assoc w R | Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) | |||||
fgd1 | 490984 | c.202_204delCTGinsAC | frameshift_variant&missense_variant | 0.41 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 0.34 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491194 | c.412_414delCTAinsTG | frameshift_variant&stop_gained | 0.56 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761110 | p.Asp435Val | missense_variant | 0.19 | rifampicin | Assoc w R | |
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.51 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303954 | c.1024_1026delGAAinsCG | frameshift_variant&missense_variant | 0.4 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.74 | streptomycin | Uncertain significance | Mutation from literature |
rrs | 1472359 | n.514A>C | non_coding_transcript_exon_variant | 0.26 | streptomycin | Assoc w R | |
rrs | 1473247 | n.1402C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Assoc w R | |
amikacin | Assoc w R - Interim | ||||||
kanamycin | Assoc w R - Interim | ||||||
inhA | 1673425 | c.-777C>T | upstream_gene_variant | 1.0 | ethionamide | Assoc w R | Alias fabG1_c.-15C>T |
isoniazid | Assoc w R | Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) | |||||
tlyA | 1918258 | c.319_321delCACinsGA | frameshift_variant&missense_variant | 0.26 | capreomycin | Assoc w R | |
tlyA | 1918315 | c.376_378delCCTinsGG | frameshift_variant&missense_variant | 0.24 | capreomycin | Assoc w R | |
katG | 2147347 | c.-2237_*6541del | transcript_ablation | 0.99 | isoniazid | Assoc w R | High-level resistance |
pncA | 2288703 | p.Val180Gly | missense_variant | 1.0 | pyrazinamide | Assoc w R | |
ahpC | 2726112 | c.-81C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance | Mutation from literature |
fbiA | 3640900 | c.358_360delCAGinsAC | frameshift_variant&missense_variant | 0.48 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
panD | 4043869 | p.Val138Ala | missense_variant | 0.38 | pyrazinamide | Mutation from literature | |
embA | 4243217 | c.-16C>T | upstream_gene_variant | 0.9 | ethambutol | Uncertain significance | Mutation from literature |
embB | 4247448 | p.His312Arg | missense_variant | 0.56 | ethambutol | Mutation from literature | |
embB | 4247663 | p.Tyr384Asn | missense_variant | 0.3 | ethambutol | Mutation from literature | |
embB | 4247676 | p.Ala388Gly | missense_variant | 0.37 | ethambutol | Mutation from literature | |
embB | 4247708 | p.Asn399Asp | missense_variant | 0.42 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 30 | c.30C>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 42 | c.42C>T | synonymous_variant | 0.28 | isoniazid | |
dnaA | 51 | c.51C>T | synonymous_variant | 0.19 | isoniazid | |
dnaA | 195 | c.195G>T | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
dnaA | 207 | c.207T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 210 | c.210C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 219 | c.219A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 225 | c.225G>A | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
dnaA | 228 | c.228C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 510 | c.510T>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 519 | c.519C>G | synonymous_variant | 0.34 | isoniazid | Not assoc w R |
dnaA | 522 | c.522T>C | synonymous_variant | 0.34 | isoniazid | Not assoc w R - Interim |
dnaA | 525 | c.525T>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 534 | c.534T>C | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
dnaA | 558 | c.558G>C | synonymous_variant | 0.54 | isoniazid | |
dnaA | 561 | c.561C>T | synonymous_variant | 0.55 | isoniazid | |
dnaA | 567 | c.567C>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 0.59 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 0.58 | isoniazid | Not assoc w R - Interim |
dnaA | 585 | c.585A>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 588 | c.588A>C | synonymous_variant | 0.58 | isoniazid | |
dnaA | 591 | c.591C>G | synonymous_variant | 0.59 | isoniazid | |
dnaA | 600 | c.600T>G | synonymous_variant | 0.6 | isoniazid | |
dnaA | 627 | c.627G>A | synonymous_variant | 0.57 | isoniazid | |
dnaA | 645 | c.645A>C | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
dnaA | 649 | c.649C>T | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
dnaA | 654 | c.654A>G | synonymous_variant | 0.41 | isoniazid | |
dnaA | 660 | c.660G>C | synonymous_variant | 0.35 | isoniazid | Not assoc w R - Interim |
dnaA | 663 | c.663A>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 669 | c.669C>T | synonymous_variant | 0.27 | isoniazid | |
dnaA | 672 | c.672T>C | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 675 | c.675C>G | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 678 | c.678A>G | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 681 | c.681G>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 682 | c.682T>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.38 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.4 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.39 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 768 | c.768C>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.39 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.4 | isoniazid | |
dnaA | 792 | c.792C>T | synonymous_variant | 0.33 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.18 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 876 | c.876C>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.34 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.39 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.4 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.45 | isoniazid | Not assoc w R - Interim |
dnaA | 942 | c.942C>G | synonymous_variant | 0.51 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.5 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.44 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.4 | isoniazid | |
dnaA | 969 | c.969G>A | synonymous_variant | 0.45 | isoniazid | |
dnaA | 975 | c.975G>T | synonymous_variant | 0.45 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>G | synonymous_variant | 0.41 | isoniazid | Not assoc w R - Interim |
dnaA | 993 | c.993A>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 996 | c.996A>C | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
dnaA | 999 | c.999C>G | synonymous_variant | 0.41 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.58 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.5 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.49 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.46 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1137 | c.1137C>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1143 | c.1143G>C | synonymous_variant | 0.43 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1188 | c.1188G>A | synonymous_variant | 0.39 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.41 | isoniazid | |
dnaA | 1197 | c.1197T>C | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.48 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.49 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.49 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.51 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.53 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 1302 | c.1302C>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1375 | c.1375T>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1389 | c.1389C>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.41 | isoniazid | |
dnaA | 1395 | c.1395G>C | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.46 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.49 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.51 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.56 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1470 | c.1470C>T | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1485 | c.1485A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1488 | c.1488A>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1497 | c.1497T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1506 | c.1506T>G | synonymous_variant | 0.28 | isoniazid | |
gyrB | 5396 | p.Ala53Ser | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5782 | c.543A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5788 | c.549G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5791 | c.552A>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5803 | c.564A>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5806 | c.567C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5809 | c.570C>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5812 | c.573C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5849 | c.610C>T | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5863 | c.624G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5873 | c.634A>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5880 | p.Thr214Ser | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5882 | c.643_645delCAAinsAC | frameshift_variant&missense_variant | 0.27 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 5887 | p.Asp216Glu | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5902 | c.663A>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5905 | c.666G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6091 | c.852G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6100 | c.861G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6123 | p.Ala295Gly | missense_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6130 | c.891T>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6139 | c.900G>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6196 | c.957C>T | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6415 | c.-887G>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6427 | c.-875T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6670 | c.1431G>A | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 0.62 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6763 | c.1524G>C | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6787 | c.-515G>A | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6916 | c.-386G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7015 | c.-287G>A | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7075 | c.-227T>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7124 | c.1885_1887delTCGinsAC | frameshift_variant&missense_variant | 0.25 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 7234 | c.1995C>T | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7246 | c.2007T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7252 | c.-50G>C | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7256 | c.2017_2019delCTGinsTA | frameshift_variant&stop_gained | 0.19 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 7307 | c.6A>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7317 | c.16T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7324 | c.23_24insAGG | disruptive_inframe_insertion | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7334 | c.33G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7335 | p.Leu12Val | missense_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7347 | c.46_48delGAAinsCG | frameshift_variant&missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7355 | c.54T>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7406 | c.105G>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7412 | c.111C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7436 | c.135C>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7712 | p.Leu137Phe | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7775 | c.474C>A | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7790 | c.489G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7796 | c.495G>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7814 | c.513C>G | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7823 | c.522G>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7832 | c.531G>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7853 | c.552C>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7886 | c.585T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8078 | c.777A>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>A | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>A | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8135 | c.834C>G | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | c.946_948delATCinsGG | frameshift_variant&missense_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8276 | c.975G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.52 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8387 | c.1086C>T | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>G | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8405 | c.1104C>T | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8442 | c.1141C>T | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>T | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8465 | c.1164C>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8472 | c.1171C>T | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8552 | c.1251C>A | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8576 | c.1275C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8579 | c.1278C>T | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8597 | c.1296C>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318_1320delTTGinsCA | frameshift_variant&missense_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8696 | c.1395G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8730 | p.Gly477Arg | missense_variant | 0.38 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8807 | c.1506C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8816 | c.1515C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.25 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8837 | c.1536C>T | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.41 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.19 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9056 | c.1755C>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9062 | c.1761C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9104 | c.1803C>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>G | synonymous_variant | 0.6 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9152 | c.1851C>T | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.65 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9224 | c.1923C>T | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.68 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>A | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9365 | c.2064G>A | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>G | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9413 | c.2112G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9602 | c.2301T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9611 | p.Asp770Glu | missense_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9626 | c.2325T>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9629 | c.2328C>G | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9630 | p.Val777Ile | missense_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9635 | c.2334T>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9638 | c.2337C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9641 | c.2340C>A | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9644 | c.2343T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9650 | c.2349G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9656 | c.2355C>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9665 | c.2364A>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9666 | p.Arg789Gly | missense_variant | 0.53 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9674 | c.2373T>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9704 | c.2403T>G | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9708 | c.2407T>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9716 | c.2415T>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9727 | p.Gly809Glu | missense_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9729 | p.Asp810Asn | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9734 | c.2433A>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9749 | c.2448G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9755 | c.2454C>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13291 | p.Asp90Asn | missense_variant | 0.2 | isoniazid | |
Rv0010c | 13320 | p.Arg80Leu | missense_variant | 0.2 | isoniazid | |
Rv0010c | 13349 | p.Ile70Met | missense_variant | 0.21 | isoniazid | |
Rv0010c | 13879 | c.-321T>C | upstream_gene_variant | 0.22 | isoniazid | |
Rv0010c | 13890 | c.-332T>C | upstream_gene_variant | 0.3 | isoniazid | |
Rv0010c | 13893 | c.-335T>G | upstream_gene_variant | 0.31 | isoniazid | |
Rv0010c | 13897 | c.-339C>T | upstream_gene_variant | 0.33 | isoniazid | |
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.36 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 0.35 | isoniazid | |
fgd1 | 490782 | c.-1G>C | upstream_gene_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.47 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.48 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.63 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>G | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490962 | c.180T>G | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490977 | c.195C>G | synonymous_variant | 0.39 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490987 | p.Leu69Thr | missense_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491001 | c.219G>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491077 | p.Asn99Asp | missense_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491082 | c.300T>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491097 | c.315G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491130 | c.348C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491173 | c.391C>A | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491184 | c.402A>G | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.59 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491302 | p.Ile174Val | missense_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491307 | c.525C>G | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491313 | c.531C>G | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491319 | c.537G>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491325 | c.543G>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491337 | c.555C>G | synonymous_variant | 0.32 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491340 | c.558C>G | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.34 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491535 | c.753G>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491553 | c.771G>A | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>A | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491649 | c.867C>T | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491658 | c.876A>G | synonymous_variant | 0.59 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491661 | c.879C>G | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491673 | c.891A>C | synonymous_variant | 0.47 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 0.47 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491687 | p.Thr302Lys | missense_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491697 | c.915G>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491709 | c.927A>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
mshA | 575011 | c.-337G>A | upstream_gene_variant | 0.21 | ethionamide | |
isoniazid | ||||||
mshA | 575018 | c.-330C>G | upstream_gene_variant | 0.29 | ethionamide | |
isoniazid | ||||||
mshA | 575022 | c.-326C>T | upstream_gene_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575030 | c.-318T>C | upstream_gene_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575034 | c.-314_-312delTTAinsAG | upstream_gene_variant | 0.33 | ethionamide | |
isoniazid | ||||||
mshA | 575042 | c.-306T>C | upstream_gene_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575052 | c.-296G>C | upstream_gene_variant | 0.35 | ethionamide | |
isoniazid | ||||||
mshA | 575057 | c.-291G>C | upstream_gene_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 575060 | c.-288G>C | upstream_gene_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 575063 | c.-285T>C | upstream_gene_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 575075 | c.-273T>C | upstream_gene_variant | 0.43 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575084 | c.-264T>C | upstream_gene_variant | 0.53 | ethionamide | |
isoniazid | ||||||
mshA | 575117 | c.-231T>C | upstream_gene_variant | 0.51 | ethionamide | |
isoniazid | ||||||
mshA | 575118 | c.-230_-228delACGinsGC | upstream_gene_variant | 0.51 | ethionamide | |
isoniazid | ||||||
mshA | 575124 | c.-224_-222delGGGinsCC | upstream_gene_variant | 0.51 | ethionamide | |
isoniazid | ||||||
mshA | 575137 | c.-211C>G | upstream_gene_variant | 0.56 | ethionamide | |
isoniazid | ||||||
mshA | 575144 | c.-204T>C | upstream_gene_variant | 0.56 | ethionamide | |
isoniazid | ||||||
mshA | 575154 | c.-194_-192delGTGinsCC | upstream_gene_variant | 0.53 | ethionamide | |
isoniazid | ||||||
mshA | 575161 | c.-187T>C | upstream_gene_variant | 0.54 | ethionamide | |
isoniazid | ||||||
mshA | 575521 | c.174A>C | synonymous_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 575527 | c.180G>C | synonymous_variant | 0.4 | ethionamide | |
isoniazid | ||||||
mshA | 575536 | c.189T>C | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575542 | c.195C>A | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575561 | p.Met72Val | missense_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575569 | c.222A>G | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575571 | p.Ser75Thr | missense_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575576 | c.229C>T | synonymous_variant | 0.46 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575581 | c.234C>T | synonymous_variant | 0.47 | ethionamide | |
isoniazid | ||||||
mshA | 575587 | c.240C>G | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575590 | c.243T>C | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575623 | c.276C>G | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
mshA | 575641 | c.294A>G | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
mshA | 575647 | c.300G>C | synonymous_variant | 0.37 | ethionamide | |
isoniazid | ||||||
mshA | 575649 | p.Val101Ala | missense_variant | 0.4 | ethionamide | |
isoniazid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575662 | c.315C>G | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
mshA | 575665 | c.318G>A | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
mshA | 575674 | c.327G>C | synonymous_variant | 0.48 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>A | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575701 | c.354G>A | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575704 | c.357T>G | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.47 | ethionamide | |
isoniazid | ||||||
mshA | 575719 | c.372C>T | synonymous_variant | 0.47 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.51 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.5 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.49 | ethionamide | |
isoniazid | ||||||
mshA | 575752 | c.405G>C | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575755 | c.408G>A | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
mshA | 575756 | c.409C>T | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
mshA | 575770 | c.423G>A | synonymous_variant | 0.43 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.43 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575809 | c.462C>T | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.57 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.58 | ethionamide | |
isoniazid | ||||||
mshA | 575833 | c.486C>G | synonymous_variant | 0.56 | ethionamide | |
isoniazid | ||||||
mshA | 575845 | c.498C>T | synonymous_variant | 0.59 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.65 | ethionamide | |
isoniazid | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.64 | ethionamide | |
isoniazid | ||||||
mshA | 575887 | c.540G>C | synonymous_variant | 0.63 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.62 | ethionamide | |
isoniazid | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.61 | ethionamide | |
isoniazid | ||||||
mshA | 575907 | p.Ala187Val | missense_variant | 0.41 | ethionamide | Not assoc w R |
isoniazid | Not assoc w R | |||||
mshA | 575917 | p.Asp190Glu | missense_variant | 0.52 | ethionamide | |
isoniazid | ||||||
mshA | 575920 | c.573C>G | synonymous_variant | 0.52 | ethionamide | |
isoniazid | ||||||
mshA | 575924 | p.Gly193Ser | missense_variant | 0.52 | ethionamide | |
isoniazid | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.47 | ethionamide | |
isoniazid | ||||||
mshA | 575950 | c.603C>G | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.25 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.41 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.42 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.44 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.46 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619594 | c.-297G>T | upstream_gene_variant | 0.47 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619609 | c.-282G>C | upstream_gene_variant | 0.55 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.57 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619645 | c.-246G>C | upstream_gene_variant | 0.55 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.52 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619668 | c.-223_-222delCGinsGC | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>T | upstream_gene_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619676 | c.-215C>G | upstream_gene_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619697 | c.-194_-192delAGGinsCC | upstream_gene_variant | 0.28 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619705 | c.-186G>C | upstream_gene_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620265 | c.375C>G | synonymous_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620298 | c.408G>C | synonymous_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620310 | c.420C>T | synonymous_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.46 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.52 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.52 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.52 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.5 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620373 | c.483C>T | synonymous_variant | 0.51 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.52 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.49 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.49 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.54 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.53 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620421 | c.531G>C | synonymous_variant | 0.51 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620424 | c.534G>C | synonymous_variant | 0.49 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.49 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>A | synonymous_variant | 0.47 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620460 | c.570T>G | synonymous_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620461 | p.Val191Ile | missense_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620481 | c.591T>G | synonymous_variant | 0.27 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620482 | p.Val198Leu | missense_variant | 0.27 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | p.Ile245Met | missense_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Uncertain significance | |||||
Rv0565c | 656052 | c.1419A>C | synonymous_variant | 0.39 | ethionamide | |
Rv0565c | 656073 | c.1396_1398delTTGinsCC | frameshift_variant&missense_variant | 0.39 | ethionamide | Uncertain significance |
Rv0565c | 656076 | c.1395C>T | synonymous_variant | 0.39 | ethionamide | |
Rv0565c | 656085 | c.1386A>G | synonymous_variant | 0.37 | ethionamide | |
Rv0565c | 656088 | c.1383A>G | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 656091 | c.1380T>C | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656100 | c.1371G>C | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 656112 | c.1359C>G | synonymous_variant | 0.37 | ethionamide | |
Rv0565c | 656265 | c.1206G>C | synonymous_variant | 0.43 | ethionamide | |
Rv0565c | 656268 | p.Met401Ile | missense_variant | 0.43 | ethionamide | |
Rv0565c | 656277 | c.1194C>G | synonymous_variant | 0.43 | ethionamide | |
Rv0565c | 656289 | c.1182C>G | synonymous_variant | 0.4 | ethionamide | |
Rv0565c | 656298 | c.1173G>C | synonymous_variant | 0.4 | ethionamide | |
Rv0565c | 656304 | c.1167T>C | synonymous_variant | 0.38 | ethionamide | |
Rv0565c | 656325 | c.1146C>G | synonymous_variant | 0.38 | ethionamide | |
Rv0565c | 656391 | c.1080C>G | synonymous_variant | 0.23 | ethionamide | |
Rv0565c | 656402 | p.Ala357Thr | missense_variant | 0.35 | ethionamide | |
Rv0565c | 656412 | c.1059T>C | synonymous_variant | 0.38 | ethionamide | |
Rv0565c | 656418 | c.1053A>G | synonymous_variant | 0.44 | ethionamide | |
Rv0565c | 656423 | c.1048T>C | synonymous_variant | 0.44 | ethionamide | |
Rv0565c | 656448 | c.1021_1023delATTinsGC | frameshift_variant&missense_variant | 0.52 | ethionamide | Uncertain significance |
Rv0565c | 656454 | c.1017G>C | synonymous_variant | 0.52 | ethionamide | |
Rv0565c | 656457 | c.1014T>C | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 656469 | c.1002T>C | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 656475 | c.996A>G | synonymous_variant | 0.51 | ethionamide | |
Rv0565c | 656484 | c.987T>C | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 656487 | c.984T>C | synonymous_variant | 0.47 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656493 | c.978C>G | synonymous_variant | 0.46 | ethionamide | |
Rv0565c | 656502 | c.969C>T | synonymous_variant | 0.42 | ethionamide | |
Rv0565c | 656511 | c.960T>C | synonymous_variant | 0.39 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656526 | p.Glu315Asp | missense_variant | 0.34 | ethionamide | |
Rv0565c | 656535 | c.936C>G | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 656539 | p.Ser311Ala | missense_variant | 0.25 | ethionamide | |
Rv0565c | 656946 | c.525T>C | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 656978 | p.Ala165Thr | missense_variant | 0.19 | ethionamide | |
Rv0565c | 656983 | p.Gly163Asp | missense_variant | 0.19 | ethionamide | |
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657219 | p.Ala84Val | missense_variant | 0.27 | ethionamide | |
Rv0565c | 657231 | c.238_240delATCinsGG | frameshift_variant&missense_variant | 0.4 | ethionamide | Uncertain significance |
Rv0565c | 657237 | c.234A>G | synonymous_variant | 0.44 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.49 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.48 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.49 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.51 | ethionamide | |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.62 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.65 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.63 | ethionamide | |
Rv0565c | 657327 | c.144C>G | synonymous_variant | 0.6 | ethionamide | |
Rv0565c | 657337 | p.Arg45Gln | missense_variant | 0.64 | ethionamide | Uncertain significance |
Rv0565c | 657342 | c.129T>C | synonymous_variant | 0.63 | ethionamide | |
Rv0565c | 657347 | c.124A>C | synonymous_variant | 0.62 | ethionamide | |
Rv0565c | 657348 | c.123A>G | synonymous_variant | 0.62 | ethionamide | |
Rv0565c | 657356 | p.Ile39Val | missense_variant | 0.68 | ethionamide | |
Rv0565c | 657372 | c.99G>C | synonymous_variant | 0.62 | ethionamide | |
Rv0565c | 657375 | c.96C>T | synonymous_variant | 0.6 | ethionamide | |
Rv0565c | 657385 | p.Ile29Thr | missense_variant | 0.52 | ethionamide | |
Rv0565c | 657399 | c.72G>C | synonymous_variant | 0.33 | ethionamide | |
Rv0565c | 657403 | p.Gly23Asp | missense_variant | 0.34 | ethionamide | |
Rv0565c | 657405 | c.64_66delCTGinsAT | frameshift_variant&missense_variant | 0.33 | ethionamide | Uncertain significance |
Rv0565c | 657408 | c.63A>C | synonymous_variant | 0.31 | ethionamide | |
Rv0565c | 657560 | c.-90G>C | upstream_gene_variant | 0.26 | ethionamide | |
Rv0565c | 657563 | c.-93T>C | upstream_gene_variant | 0.3 | ethionamide | |
Rv0565c | 657571 | c.-101T>C | upstream_gene_variant | 0.32 | ethionamide | |
Rv0565c | 657572 | c.-102A>G | upstream_gene_variant | 0.31 | ethionamide | |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 0.4 | ethionamide | |
Rv0565c | 657592 | c.-122A>C | upstream_gene_variant | 0.47 | ethionamide | |
Rv0565c | 657600 | c.-132_-131delCA | upstream_gene_variant | 0.49 | ethionamide | |
Rv0565c | 657606 | c.-136T>G | upstream_gene_variant | 0.48 | ethionamide | |
Rv0565c | 657607 | c.-138_-137insCA | upstream_gene_variant | 0.49 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 0.69 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.71 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.7 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.68 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.63 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.6 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.42 | ethionamide | |
hadA | 731717 | c.-213T>G | upstream_gene_variant | 0.28 | isoniazid | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.47 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.5 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.57 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.59 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.58 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.56 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 0.52 | isoniazid | |
hadA | 731840 | c.-90G>C | upstream_gene_variant | 0.39 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.38 | isoniazid | |
hadA | 731849 | c.-81C>T | upstream_gene_variant | 0.34 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 0.34 | isoniazid | |
hadA | 731864 | c.-66C>T | upstream_gene_variant | 0.22 | isoniazid | |
hadA | 732238 | c.309G>C | synonymous_variant | 0.22 | isoniazid | |
hadA | 732253 | c.324T>C | synonymous_variant | 0.38 | isoniazid | |
hadA | 732259 | c.330T>C | synonymous_variant | 0.46 | isoniazid | |
hadA | 732268 | c.339T>G | synonymous_variant | 0.49 | isoniazid | |
hadA | 732270 | p.Glu114Val | missense_variant | 0.48 | isoniazid | |
hadA | 732272 | p.Ala115Ser | missense_variant | 0.51 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.65 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.67 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.68 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.67 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.72 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.7 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.67 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.71 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.71 | isoniazid | |
nusG | 734078 | c.-176C>G | upstream_gene_variant | 0.32 | rifampicin | Uncertain significance |
nusG | 734093 | c.-161A>C | upstream_gene_variant | 0.34 | rifampicin | |
nusG | 734096 | c.-158C>T | upstream_gene_variant | 0.34 | rifampicin | |
nusG | 734102 | c.-152G>C | upstream_gene_variant | 0.34 | rifampicin | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.34 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.34 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.35 | rifampicin | Uncertain significance |
nusG | 734123 | c.-131C>G | upstream_gene_variant | 0.36 | rifampicin | |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.36 | rifampicin | |
nusG | 734132 | c.-122G>C | upstream_gene_variant | 0.35 | rifampicin | |
nusG | 734135 | c.-119G>C | upstream_gene_variant | 0.35 | rifampicin | |
nusG | 734144 | c.-110G>C | upstream_gene_variant | 0.35 | rifampicin | |
nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.33 | rifampicin | |
nusG | 734340 | c.87T>C | synonymous_variant | 0.27 | rifampicin | |
nusG | 734352 | c.99T>C | synonymous_variant | 0.42 | rifampicin | |
nusG | 734360 | p.Ala36Val | missense_variant | 0.53 | rifampicin | Uncertain significance |
nusG | 734370 | c.117A>G | synonymous_variant | 0.59 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.6 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.73 | rifampicin | |
nusG | 734418 | c.165C>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
nusG | 734421 | c.168A>G | synonymous_variant | 0.76 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.78 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.75 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.76 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.75 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.74 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.75 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.76 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.69 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.67 | rifampicin | |
nusG | 734601 | c.348C>G | synonymous_variant | 0.65 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.64 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.5 | rifampicin | |
nusG | 734631 | c.378G>C | synonymous_variant | 0.44 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 0.42 | rifampicin | |
nusG | 734637 | c.384G>C | synonymous_variant | 0.43 | rifampicin | |
nusG | 734643 | c.390G>C | synonymous_variant | 0.42 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 0.36 | rifampicin | |
nusG | 734658 | c.405A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R |
nusG | 734673 | c.420A>G | synonymous_variant | 0.25 | rifampicin | |
nusG | 734676 | c.423G>C | synonymous_variant | 0.24 | rifampicin | |
nusG | 734679 | c.426C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
nusG | 734680 | p.Ala143Thr | missense_variant | 0.22 | rifampicin | |
nusG | 734772 | c.519G>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734775 | c.522C>G | synonymous_variant | 0.24 | rifampicin | |
nusG | 734781 | c.528A>G | synonymous_variant | 0.24 | rifampicin | |
nusG | 734784 | c.531G>A | synonymous_variant | 0.25 | rifampicin | |
nusG | 734787 | c.534T>C | synonymous_variant | 0.27 | rifampicin | |
nusG | 734792 | p.Val180Ala | missense_variant | 0.33 | rifampicin | |
nusG | 734794 | p.Val181Ile | missense_variant | 0.37 | rifampicin | Uncertain significance |
nusG | 734814 | c.561G>C | synonymous_variant | 0.67 | rifampicin | |
nusG | 734826 | c.573A>C | synonymous_variant | 0.68 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
nusG | 734841 | c.588G>C | synonymous_variant | 0.67 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.66 | rifampicin | |
nusG | 734850 | c.597C>G | synonymous_variant | 0.68 | rifampicin | |
nusG | 734853 | c.600A>G | synonymous_variant | 0.67 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 0.67 | rifampicin | |
nusG | 734882 | p.Ala210Gly | missense_variant | 0.61 | rifampicin | |
nusG | 734886 | c.633A>G | synonymous_variant | 0.59 | rifampicin | |
nusG | 734910 | c.657C>G | synonymous_variant | 0.34 | rifampicin | |
nusG | 734913 | c.660C>G | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760030 | p.Asn75Thr | missense_variant | 0.2 | rifampicin | Uncertain significance |
rpoB | 760034 | c.228A>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760040 | c.234T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760046 | c.240G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760060 | p.Tyr85Leu | missense_variant | 0.41 | rifampicin | |
rpoB | 760067 | c.261G>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 760070 | c.264T>G | synonymous_variant | 0.5 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.61 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.64 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.66 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.73 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.69 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.69 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.65 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.63 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.62 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760472 | c.666C>T | synonymous_variant | 0.56 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.6 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.56 | rifampicin | |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.61 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.67 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.78 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 760680 | p.Asn292Asp | missense_variant | 0.24 | rifampicin | |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 760715 | c.909C>G | synonymous_variant | 0.66 | rifampicin | |
rpoB | 760718 | c.912C>T | synonymous_variant | 0.64 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.53 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.46 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.43 | rifampicin | |
rpoB | 760775 | c.969G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 0.43 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.5 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.54 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.53 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.55 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Pro | missense_variant | 0.61 | rifampicin | |
rpoB | 760859 | c.1053T>C | synonymous_variant | 0.63 | rifampicin | |
rpoB | 760862 | c.1056G>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.68 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.66 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.63 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.62 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.62 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.72 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.71 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.78 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.69 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.67 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.71 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.67 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.65 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.61 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.55 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.34 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 761439 | c.1633_1635delGACinsAG | frameshift_variant&missense_variant | 0.33 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.32 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.41 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.55 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.68 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.72 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.71 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.61 | rifampicin | |
rpoB | 761720 | c.1914C>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 0.29 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.53 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.53 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.57 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.58 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.66 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.64 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.66 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.69 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.79 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.67 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.64 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.65 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.78 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.68 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.68 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.68 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.72 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.83 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.81 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.81 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.79 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.78 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.72 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.73 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.73 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.69 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.69 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.65 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.64 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.65 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.66 | rifampicin | |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.68 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.62 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.61 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.61 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.55 | rifampicin | |
rpoC | 762581 | c.-789T>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoC | 762582 | c.-788T>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoC | 762758 | c.-612G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 0.29 | rifampicin | Uncertain significance |
rpoB | 762788 | c.2982G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoB | 762810 | c.3004_3006delGCCinsTG | frameshift_variant&missense_variant | 0.39 | rifampicin | |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.42 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.64 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.65 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 763067 | c.-303C>G | upstream_gene_variant | 0.65 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.54 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.54 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.56 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.54 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.53 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.52 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.58 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.42 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.4 | rifampicin | |
rpoB | 763268 | c.3462C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.32 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.34 | rifampicin | Uncertain significance |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.63 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763492 | c.123G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 763657 | c.288G>A | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.69 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.68 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.57 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.59 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.56 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.56 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 763951 | c.582G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 763960 | c.591T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 0.51 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 0.49 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.48 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.43 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.6 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.61 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.56 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.59 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.35 | rifampicin | |
rpoC | 764392 | c.1023C>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.63 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.71 | rifampicin | |
rpoC | 764551 | c.1182G>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.69 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.62 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.56 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765011 | c.1642_1643delAGinsTC | synonymous_variant | 0.47 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765055 | c.1686C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765208 | c.1839T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 765220 | c.1851A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765233 | p.Ala622Ser | missense_variant | 0.27 | rifampicin | |
rpoC | 765241 | c.1872C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765244 | c.1875T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765247 | c.1878C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765248 | c.1879T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765251 | c.1882_1884delAGCinsTCG | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765292 | c.1923G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.41 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.49 | rifampicin | Uncertain significance |
rpoC | 765330 | p.Ser654Asn | missense_variant | 0.52 | rifampicin | Uncertain significance |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.59 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 765364 | c.1995G>A | synonymous_variant | 0.6 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.64 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.7 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.68 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.66 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.65 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.65 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.66 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.64 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.64 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.63 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.62 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.7 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.7 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 765947 | c.2578T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.7 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.65 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.66 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.69 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.69 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.72 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.69 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 766174 | p.Asn935Lys | missense_variant | 0.26 | rifampicin | |
rpoC | 766178 | p.Ile937Val | missense_variant | 0.26 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.34 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.37 | rifampicin | |
rpoC | 766288 | c.2919C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766327 | c.2958C>A | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766366 | c.2997C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.69 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.65 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.69 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.69 | rifampicin | |
rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.69 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.69 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.68 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.64 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.76 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.75 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.76 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.64 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.62 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.7 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.73 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.66 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.23 | rifampicin | |
rpoC | 767284 | c.3915C>T | synonymous_variant | 0.2 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.26 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.31 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775973 | c.2506_2508delTTGinsCC | frameshift_variant&missense_variant | 0.24 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.31 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775991 | c.2490G>A | synonymous_variant | 0.27 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775997 | c.2484T>C | synonymous_variant | 0.33 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776000 | c.2479_2481delCTGinsAC | frameshift_variant&missense_variant | 0.32 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776005 | p.Ile826Leu | missense_variant | 0.27 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.31 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776030 | c.2451G>A | synonymous_variant | 0.2 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776182 | p.Asp767Asn | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R | |||||
mmpL5 | 776646 | p.Val612Thr | missense_variant | 0.22 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776654 | c.1827A>C | synonymous_variant | 0.28 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776664 | p.Thr606Gly | missense_variant | 0.3 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776675 | c.1806G>A | synonymous_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776678 | c.1803G>C | synonymous_variant | 0.35 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776684 | c.1797G>A | synonymous_variant | 0.2 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776693 | p.Val596Ala | missense_variant | 0.35 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776705 | c.1776C>T | synonymous_variant | 0.37 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776738 | p.Ile581Met | missense_variant | 0.3 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776741 | c.1740C>G | synonymous_variant | 0.23 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776756 | p.Asp575Glu | missense_variant | 0.25 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777095 | c.1386T>C | synonymous_variant | 0.29 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777101 | c.1380C>G | synonymous_variant | 0.33 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777110 | c.1371T>G | synonymous_variant | 0.36 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777115 | p.Met456Leu | missense_variant | 0.37 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777116 | c.1365C>T | synonymous_variant | 0.37 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777133 | p.Val450Ile | missense_variant | 0.46 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777158 | c.1323C>G | synonymous_variant | 0.54 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 0.53 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.53 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.53 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777191 | c.1290C>G | synonymous_variant | 0.47 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777194 | c.1287A>G | synonymous_variant | 0.46 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777206 | c.1275A>G | synonymous_variant | 0.42 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777212 | c.1267_1269delGCCinsAG | frameshift_variant&missense_variant | 0.41 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 777215 | c.1266C>G | synonymous_variant | 0.4 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777218 | c.1263G>A | synonymous_variant | 0.41 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777251 | c.1230C>G | synonymous_variant | 0.25 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777254 | c.1227G>C | synonymous_variant | 0.22 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
rpsL | 781182 | c.-378G>C | upstream_gene_variant | 0.25 | streptomycin | |
rpsL | 781185 | c.-375T>C | upstream_gene_variant | 0.29 | streptomycin | |
rpsL | 781194 | c.-366G>C | upstream_gene_variant | 0.4 | streptomycin | |
rpsL | 781197 | c.-363A>G | upstream_gene_variant | 0.4 | streptomycin | |
rpsL | 781224 | c.-336T>C | upstream_gene_variant | 0.41 | streptomycin | |
rpsL | 781230 | c.-330T>C | upstream_gene_variant | 0.42 | streptomycin | |
rpsL | 781232 | c.-328C>T | upstream_gene_variant | 0.42 | streptomycin | |
rpsL | 781234 | c.-326G>T | upstream_gene_variant | 0.43 | streptomycin | |
rpsL | 781240 | c.-320A>T | upstream_gene_variant | 0.43 | streptomycin | |
rpsL | 781257 | c.-303G>C | upstream_gene_variant | 0.41 | streptomycin | |
rpsL | 781269 | c.-291C>T | upstream_gene_variant | 0.38 | streptomycin | |
rpsL | 781270 | c.-290A>C | upstream_gene_variant | 0.36 | streptomycin | |
rpsL | 781276 | c.-284A>C | upstream_gene_variant | 0.33 | streptomycin | |
rpsL | 781285 | c.-275_-273delACAinsGC | upstream_gene_variant | 0.25 | streptomycin | |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781571 | c.12C>T | synonymous_variant | 0.44 | streptomycin | |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.62 | streptomycin | |
rpsL | 781605 | p.Ile16Val | missense_variant | 0.62 | streptomycin | Uncertain significance |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.62 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.71 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.73 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.76 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.77 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.71 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.75 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.75 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.78 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.76 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.75 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.76 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.76 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.75 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.78 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.74 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.73 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.71 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.72 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.72 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.68 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.68 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.72 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.7 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.7 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.47 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.55 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.55 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.59 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.65 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.63 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.63 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.63 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.68 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.67 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.65 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.65 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.66 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.68 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.68 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.63 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.62 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.6 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.68 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.55 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.54 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.52 | linezolid | |
rplC | 800875 | c.67_69delGTAinsAT | frameshift_variant&missense_variant | 0.52 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.53 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.52 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.51 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.51 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.52 | linezolid | |
rplC | 800934 | c.126C>G | synonymous_variant | 0.41 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.33 | linezolid | |
rplC | 800939 | p.Arg44Gln | missense_variant | 0.34 | linezolid | |
rplC | 800946 | c.138T>C | synonymous_variant | 0.35 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 0.36 | linezolid | |
rplC | 800967 | c.159C>G | synonymous_variant | 0.37 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 0.36 | linezolid | Not assoc w R - Interim |
rplC | 800982 | c.174C>T | synonymous_variant | 0.44 | linezolid | |
rplC | 800985 | c.177A>G | synonymous_variant | 0.45 | linezolid | |
rplC | 801004 | p.Leu66Val | missense_variant | 0.29 | linezolid | |
rplC | 801009 | c.201A>C | synonymous_variant | 0.3 | linezolid | |
rplC | 801127 | p.Ala107Thr | missense_variant | 0.34 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 0.38 | linezolid | |
rplC | 801147 | c.339T>C | synonymous_variant | 0.47 | linezolid | |
rplC | 801150 | c.342G>C | synonymous_variant | 0.51 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 0.5 | linezolid | |
rplC | 801156 | c.348T>A | synonymous_variant | 0.5 | linezolid | |
rplC | 801168 | c.360C>G | synonymous_variant | 0.56 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 0.55 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.56 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.57 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.57 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.4 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.4 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.35 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.31 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.33 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.33 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.31 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.31 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.31 | linezolid | |
rplC | 801285 | c.477G>C | synonymous_variant | 0.31 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.43 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.39 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.42 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.48 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.47 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.53 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.52 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.57 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.63 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.66 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.61 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.61 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.55 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.53 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.53 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.58 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.58 | linezolid | |
Rv1129c | 1254056 | p.Asp160Ala | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
fbiC | 1303470 | c.540T>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303476 | c.546G>C | synonymous_variant | 0.22 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303480 | p.Gln184Glu | missense_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303489 | c.559C>T | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303497 | c.567G>A | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303501 | c.571C>T | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303641 | c.711C>T | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303681 | c.751T>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.47 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.51 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304040 | c.1110C>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304049 | c.1119T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304050 | c.1120T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304058 | c.1128G>A | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304059 | c.1129C>T | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304085 | c.1155C>T | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304127 | c.1197A>G | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304132 | p.Ala401Gly | missense_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304142 | c.1212G>C | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304161 | p.Arg411Ser | missense_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304169 | c.1239T>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304174 | p.Val415Ala | missense_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304184 | c.1254G>C | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304187 | c.1257T>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304208 | c.1278C>T | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304223 | c.1293G>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304226 | c.1296C>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304227 | p.Met433Leu | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304499 | c.1569T>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304511 | c.1581C>G | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304535 | c.1605G>A | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304545 | p.Val539Thr | missense_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304553 | c.1623C>T | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.47 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.5 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.67 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305045 | c.2115A>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305063 | c.2133G>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305075 | c.2145T>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305081 | c.2151G>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305090 | c.2160C>G | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305092 | p.Ala721Gly | missense_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305099 | c.2169T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305114 | c.2184T>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305117 | c.2187T>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305126 | c.2196T>C | synonymous_variant | 0.34 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1305177 | c.2247A>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305181 | c.2251T>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305186 | c.2256C>T | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305195 | c.2265T>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305201 | c.2271G>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305204 | c.2274C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305210 | c.2280G>A | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305215 | p.Ser762Thr | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305231 | c.2301C>A | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305234 | c.2304G>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305240 | c.2310T>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305243 | c.2313T>G | synonymous_variant | 0.35 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305244 | c.2314T>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305252 | c.2322G>A | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305276 | c.2346G>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305279 | p.His783Gln | missense_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305282 | c.2352T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305297 | c.2367G>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305372 | c.2442G>A | synonymous_variant | 0.31 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305384 | c.2454G>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305396 | c.2466C>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>G | synonymous_variant | 0.3 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305417 | c.2487C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305423 | c.2493T>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305430 | p.Val834Thr | missense_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305444 | c.2514A>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364856 | c.444C>G | synonymous_variant | 0.28 | pyrazinamide | |
sigE | 1364862 | c.450C>A | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364868 | c.456T>G | synonymous_variant | 0.35 | pyrazinamide | |
sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 0.43 | pyrazinamide | Uncertain significance |
sigE | 1364898 | c.486C>T | synonymous_variant | 0.45 | pyrazinamide | |
sigE | 1364904 | p.Asp164Glu | missense_variant | 0.42 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.4 | pyrazinamide | |
sigE | 1364943 | c.531C>T | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364949 | c.537C>T | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364950 | p.Ala180Ser | missense_variant | 0.2 | pyrazinamide | |
sigE | 1365024 | c.612T>C | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1365033 | c.621G>A | synonymous_variant | 0.29 | pyrazinamide | |
sigE | 1365036 | c.624T>C | synonymous_variant | 0.36 | pyrazinamide | |
sigE | 1365042 | c.630G>C | synonymous_variant | 0.42 | pyrazinamide | |
sigE | 1365057 | c.645C>T | synonymous_variant | 0.46 | pyrazinamide | |
sigE | 1365063 | c.651A>C | synonymous_variant | 0.47 | pyrazinamide | |
sigE | 1365084 | c.672G>C | synonymous_variant | 0.4 | pyrazinamide | |
sigE | 1365087 | c.675A>C | synonymous_variant | 0.39 | pyrazinamide | |
sigE | 1365090 | c.678T>C | synonymous_variant | 0.39 | pyrazinamide | |
sigE | 1365096 | c.684G>C | synonymous_variant | 0.38 | pyrazinamide | |
sigE | 1365099 | c.687A>C | synonymous_variant | 0.39 | pyrazinamide | |
sigE | 1365114 | c.702G>A | synonymous_variant | 0.38 | pyrazinamide | |
sigE | 1365117 | c.705A>C | synonymous_variant | 0.35 | pyrazinamide | |
sigE | 1365118 | c.706C>T | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
sigE | 1365135 | c.723A>C | synonymous_variant | 0.26 | pyrazinamide | |
Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
isoniazid | Uncertain significance | |||||
pyrazinamide | Uncertain significance | |||||
atpE | 1460816 | c.-229T>C | upstream_gene_variant | 0.43 | bedaquiline | |
atpE | 1460831 | c.-214T>C | upstream_gene_variant | 0.53 | bedaquiline | |
atpE | 1460840 | c.-205A>G | upstream_gene_variant | 0.55 | bedaquiline | |
atpE | 1460852 | c.-193C>G | upstream_gene_variant | 0.55 | bedaquiline | |
atpE | 1460855 | c.-190T>C | upstream_gene_variant | 0.54 | bedaquiline | |
atpE | 1460858 | c.-187C>G | upstream_gene_variant | 0.53 | bedaquiline | |
atpE | 1460861 | c.-184C>G | upstream_gene_variant | 0.56 | bedaquiline | |
atpE | 1460882 | c.-163T>C | upstream_gene_variant | 0.49 | bedaquiline | |
atpE | 1460894 | c.-151A>G | upstream_gene_variant | 0.46 | bedaquiline | |
atpE | 1460897 | c.-148A>C | upstream_gene_variant | 0.43 | bedaquiline | |
atpE | 1460900 | c.-145T>C | upstream_gene_variant | 0.43 | bedaquiline | |
atpE | 1460915 | c.-130C>G | upstream_gene_variant | 0.31 | bedaquiline | |
atpE | 1460918 | c.-127A>G | upstream_gene_variant | 0.27 | bedaquiline | |
atpE | 1461132 | p.Val30Ile | missense_variant | 0.38 | bedaquiline | |
atpE | 1461149 | c.105T>G | synonymous_variant | 0.39 | bedaquiline | |
atpE | 1461150 | c.106_108delATCinsGT | frameshift_variant&missense_variant | 0.39 | bedaquiline | |
atpE | 1461158 | c.114T>G | synonymous_variant | 0.35 | bedaquiline | |
atpE | 1461159 | p.Val39Ile | missense_variant | 0.35 | bedaquiline | Uncertain significance |
atpE | 1461170 | c.126A>G | synonymous_variant | 0.45 | bedaquiline | |
atpE | 1461185 | c.141G>T | synonymous_variant | 0.49 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.48 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.44 | bedaquiline | |
atpE | 1461233 | c.189A>C | synonymous_variant | 0.38 | bedaquiline | |
atpE | 1461251 | c.207G>C | synonymous_variant | 0.32 | bedaquiline | |
atpE | 1461254 | c.210T>C | synonymous_variant | 0.32 | bedaquiline | |
atpE | 1461275 | c.231T>A | synonymous_variant | 0.19 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.54 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.54 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.54 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.55 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.49 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.48 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.45 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.42 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.42 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.42 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.44 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.45 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.51 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472045 | n.200T>A | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.53 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.54 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.59 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.63 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.66 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.66 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.68 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.68 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.68 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.71 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.69 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.7 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.66 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473417 | n.-241C>T | upstream_gene_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1473419 | n.-239T>C | upstream_gene_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1473420 | n.-238A>G | upstream_gene_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1473421 | n.-237G>A | upstream_gene_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1473436 | n.-222T>C | upstream_gene_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1473437 | n.-221T>C | upstream_gene_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1473653 | n.-5_2delTGTGTTTinsGTGTAA | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.76 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 |