TB-Profiler result

Run: ERR8479578
Summary

Run ID: ERR8479578

Sample name:

Date: 2024-10-05T07:26:54.595713

Number of reads: 1266327

Percentage reads mapped: 24.69

Median coverage: 29.0

Strain: lineage1.1.3.1

Spoligotype:

Drug-resistance: Sensitive

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.1.3 Indo-Oceanic RD239 1.0
lineage1.1 Indo-Oceanic RD239 1.0
lineage1.1.3.1 Indo-Oceanic RD239 1.0
La1.7.1 M.bovis None 0.05
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 627 c.627G>A synonymous_variant 0.32 isoniazid
dnaA 636 c.636C>G synonymous_variant 0.33 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.32 isoniazid Not assoc w R - Interim
dnaA 648 c.648C>T synonymous_variant 0.31 isoniazid
dnaA 654 c.654A>G synonymous_variant 0.3 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>G synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 666 c.666C>A synonymous_variant 0.29 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>T synonymous_variant 0.32 isoniazid
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.32 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.36 isoniazid
dnaA 699 c.699G>C synonymous_variant 0.37 isoniazid Not assoc w R - Interim
dnaA 702 c.702C>G synonymous_variant 0.36 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.37 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.37 isoniazid
dnaA 729 c.729C>G synonymous_variant 0.38 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>A synonymous_variant 0.32 isoniazid
dnaA 750 c.750C>G synonymous_variant 0.33 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.33 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.33 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.33 isoniazid
dnaA 769 p.Ala257Ser missense_variant 0.3 isoniazid Uncertain significance
dnaA 777 c.777A>G synonymous_variant 0.3 isoniazid
dnaA 783 c.783C>T synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 793 p.Val265Ile missense_variant 0.28 isoniazid Uncertain significance
dnaA 799 p.Val267Ile missense_variant 0.29 isoniazid
dnaA 805 c.805_807delTTGinsCTC synonymous_variant 0.3 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.29 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.27 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.26 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 864 c.864C>T synonymous_variant 0.33 isoniazid
dnaA 876 c.876C>T synonymous_variant 0.46 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.46 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.53 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.57 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.59 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.58 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.59 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.59 isoniazid Not assoc w R - Interim
dnaA 948 c.948C>T synonymous_variant 0.59 isoniazid
dnaA 955 c.955_957delAGAinsCGG synonymous_variant 0.59 isoniazid
dnaA 963 c.963C>T synonymous_variant 0.56 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.57 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.56 isoniazid
dnaA 978 c.978G>C synonymous_variant 0.56 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.52 isoniazid Not assoc w R - Interim
dnaA 987 c.987C>T synonymous_variant 0.48 isoniazid
dnaA 990 c.990A>G synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.48 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.5 isoniazid
dnaA 1011 c.1011C>G synonymous_variant 0.51 isoniazid
dnaA 1020 c.1020C>G synonymous_variant 0.48 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.44 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 0.44 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.41 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 0.4 isoniazid
dnaA 1047 p.Glu349Asp missense_variant 0.35 isoniazid
dnaA 1050 c.1050G>T synonymous_variant 0.26 isoniazid
dnaA 1055 p.Ala352Asp missense_variant 0.3 isoniazid
dnaA 1059 c.1059C>G synonymous_variant 0.3 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.32 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.33 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.34 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.36 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.34 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.3 isoniazid
dnaA 1107 c.1107C>T synonymous_variant 0.29 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.29 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.28 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 0.27 isoniazid
dnaA 1126 c.1126C>T synonymous_variant 0.27 isoniazid Not assoc w R - Interim
dnaA 1137 c.1137C>G synonymous_variant 0.28 isoniazid
dnaA 1140 c.1140C>G synonymous_variant 0.28 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.28 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.27 isoniazid
dnaA 1153 c.1153_1155delTTGinsCTC synonymous_variant 0.27 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.27 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.27 isoniazid
dnaA 1166 p.Pro389Arg missense_variant 0.27 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.27 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.26 isoniazid
dnaA 1189 p.Ile397Val missense_variant 0.26 isoniazid
dnaA 1195 c.1195_1197delCTTinsTTG synonymous_variant 0.27 isoniazid
dnaA 1220 p.Asn407Thr missense_variant 0.32 isoniazid
gyrB 6091 c.852G>T synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrB 6112 p.Met291Ile missense_variant 0.59 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrB 6115 c.876A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6142 c.903G>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6148 c.909C>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6175 c.936G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrB 6203 c.964_966delAGCinsTCG synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.56 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.61 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6324 c.1085_1086insGGCC frameshift_variant 0.45 levofloxacin Uncertain significance
moxifloxacin
gyrB 6327 c.1090_1093delGAAC frameshift_variant 0.46 levofloxacin Uncertain significance
moxifloxacin
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 6398 p.Val387Ile missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6658 c.-644G>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>T synonymous_variant 0.57 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6727 c.-575G>T upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6769 c.-533C>T upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6772 c.-530C>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.54 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.44 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>T upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 7100 c.1861T>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7123 c.-179C>G upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7138 c.-164G>A upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7156 c.1917C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7424 c.123G>A synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7433 c.132G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7460 c.159C>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7463 c.162G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7614 c.313C>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7643 c.342C>A synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7655 c.354G>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7670 c.369A>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7671 p.Pro124Ala missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCGT synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7691 c.390C>A synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427A>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7754 p.Asp151Glu missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 7763 c.462T>A synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7890 c.589C>T synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 7906 p.Phe202Tyr missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8138 c.837C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8186 c.885G>A synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8195 c.894C>A synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8240 c.939C>A synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8243 c.942C>T synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.53 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8321 c.1020C>T synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.59 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8357 c.1056G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8452 p.Ala384Val missense_variant 0.43 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8456 c.1155C>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8477 c.1176C>T synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8489 c.1188A>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 8540 c.1239C>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 p.Asp415Glu missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8639 c.1338G>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8738 c.1437G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8741 c.1440C>T synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8747 c.1446A>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>T synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8761 p.Val487Ala missense_variant 0.42 levofloxacin
moxifloxacin
gyrA 8765 p.Asp488Glu missense_variant 0.45 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.44 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8786 c.1485T>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8798 p.Ile499Met missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Pro missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8813 p.Asp504Glu missense_variant 0.51 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8849 c.1548C>T synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>A synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8952 p.Gln551Ala missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.6 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.38 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9060 p.Ala587Thr missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9077 c.1776C>T synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9098 c.1797G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9101 c.1800A>G synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9104 c.1803C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9113 c.1812C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9191 c.1890G>T synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9208 p.Lys636Arg missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 9213 p.Thr638Val missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9266 p.Asp655Glu missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9323 c.2022C>G synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9369 c.2068C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
Rv0010c 13298 p.Ile87Met missense_variant 1.0 isoniazid Not assoc w R
Rv0010c 13460 c.99T>C synonymous_variant 1.0 isoniazid Not assoc w R
fgd1 491022 c.240C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491031 c.249C>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491034 c.252C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491037 c.255C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491055 c.273C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491058 c.276C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491076 c.294G>C synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fgd1 491077 p.Asn99Asp missense_variant 0.39 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491100 c.318C>T synonymous_variant 0.52 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491115 c.333G>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491133 c.351A>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 491138 p.Glu119Ala missense_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491142 c.360C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>T synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 491184 c.402A>G synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fgd1 491190 c.408G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Lys missense_variant 0.49 pretomanid
delamanid
clofazimine
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Leu missense_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.63 pretomanid
delamanid
clofazimine
fgd1 491248 p.Arg156Lys missense_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 491280 c.498C>T synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.59 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491289 c.507C>T synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 0.57 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491313 c.531C>T synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 491316 c.534C>T synonymous_variant 0.55 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491321 p.Ala180Val missense_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491340 c.558C>T synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491346 c.564C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491355 c.573C>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491571 c.789C>T synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fgd1 491595 c.813C>T synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 491604 c.822G>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491631 c.849C>T synonymous_variant 0.32 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
mshA 575548 c.201C>G synonymous_variant 0.3 isoniazid
ethionamide
mshA 575554 c.207C>T synonymous_variant 0.29 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 0.3 isoniazid
ethionamide
mshA 575569 c.222A>G synonymous_variant 0.3 isoniazid
ethionamide
mshA 575571 p.Ser75Thr missense_variant 0.3 isoniazid
ethionamide
mshA 575576 c.229C>T synonymous_variant 0.3 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575581 p.His78Gln missense_variant 0.29 isoniazid
ethionamide
mshA 575593 c.246G>T synonymous_variant 0.31 isoniazid
ethionamide
mshA 575597 p.Ile84Val missense_variant 0.32 isoniazid
ethionamide
mshA 575609 p.Ile88Val missense_variant 0.3 isoniazid
ethionamide
mshA 575618 c.271C>A synonymous_variant 0.29 isoniazid
ethionamide
mshA 575627 p.Ala94Ser missense_variant 0.31 isoniazid
ethionamide
mshA 575633 p.Ala96Thr missense_variant 0.28 isoniazid
ethionamide
mshA 575638 c.291T>C synonymous_variant 0.27 isoniazid
ethionamide
mshA 575639 p.Pro98Ala missense_variant 0.25 isoniazid
ethionamide
mshA 575652 p.Arg102Pro missense_variant 0.37 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.38 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 0.38 isoniazid
ethionamide
mshA 575669 c.322C>T synonymous_variant 0.38 isoniazid Not assoc w R - Interim
ethionamide
mshA 575680 c.333C>T synonymous_variant 0.44 isoniazid
ethionamide
mshA 575689 c.342G>C synonymous_variant 0.49 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.53 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 0.53 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.53 isoniazid
ethionamide
mshA 575728 c.381C>A synonymous_variant 0.65 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 0.63 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.6 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 0.62 isoniazid Uncertain significance
ethionamide
mshA 575749 c.402C>G synonymous_variant 0.63 isoniazid
ethionamide
mshA 575756 c.409C>T synonymous_variant 0.63 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 0.61 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.62 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.64 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.64 isoniazid
ethionamide
mshA 575788 c.441C>T synonymous_variant 0.6 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 0.64 isoniazid
ethionamide
mshA 575800 c.453G>C synonymous_variant 0.69 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.64 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.58 isoniazid
ethionamide
mshA 575845 c.498C>G synonymous_variant 0.55 isoniazid
ethionamide
mshA 575848 c.501C>T synonymous_variant 0.54 isoniazid
ethionamide
mshA 575864 c.517_519delTTGinsCTC synonymous_variant 0.47 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.39 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.34 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.26 isoniazid
ethionamide
ccsA 620319 c.429C>T synonymous_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 620337 c.447C>G synonymous_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>T synonymous_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Ser missense_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.46 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.47 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.46 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.46 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.47 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.42 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 620427 c.537C>G synonymous_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 620436 c.546T>C synonymous_variant 0.4 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620463 c.573C>G synonymous_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620670 c.780C>T synonymous_variant 0.22 kanamycin
capreomycin
amikacin
ccsA 620676 c.786C>T synonymous_variant 0.22 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>C synonymous_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620724 c.834C>T synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620736 c.846G>C synonymous_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620764 p.Ala292Ser missense_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620835 c.945C>G synonymous_variant 0.21 kanamycin
capreomycin
amikacin
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
nusG 734116 c.-138T>C upstream_gene_variant 0.93 rifampicin Not assoc w R
nusG 734407 p.Val52Ile missense_variant 0.28 rifampicin
nusG 734415 c.162C>G synonymous_variant 0.33 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.33 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.35 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.38 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.45 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.44 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.48 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.54 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.43 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.43 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760070 c.264T>G synonymous_variant 0.42 rifampicin
rpoB 760082 c.276C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760091 c.285G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.48 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.53 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760127 c.321C>T synonymous_variant 0.59 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 0.61 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.64 rifampicin
rpoB 760151 c.345G>A synonymous_variant 0.67 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.73 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.73 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.72 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.72 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.68 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.67 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.7 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.7 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.65 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760532 c.726T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.54 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.56 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.56 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.58 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.57 rifampicin
rpoB 760574 c.768G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760585 p.Asn260Ser missense_variant 0.67 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.69 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.69 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.73 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.73 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.72 rifampicin
rpoB 760755 p.His317Asn missense_variant 0.72 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.73 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.75 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.75 rifampicin
rpoB 760784 c.978G>C synonymous_variant 0.73 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.74 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.7 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.65 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.63 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 0.67 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760848 p.Thr348Ser missense_variant 0.62 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.59 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760865 c.1059C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760868 c.1062C>T synonymous_variant 0.59 rifampicin
rpoB 760877 c.1071G>T synonymous_variant 0.59 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.6 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.57 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.57 rifampicin Uncertain significance
rpoB 760916 c.1110C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.65 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.64 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.69 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.67 rifampicin Uncertain significance
rpoB 760973 c.1167G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 0.68 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.74 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.75 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761217 p.Pro471Ser missense_variant 0.66 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.66 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 0.78 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.76 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 0.72 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.7 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.62 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.58 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.55 rifampicin
rpoB 761436 p.Ala544Thr missense_variant 0.54 rifampicin
rpoB 761451 p.Val549Thr missense_variant 0.48 rifampicin
rpoB 761457 p.Pro551Asp missense_variant 0.48 rifampicin
rpoB 761466 p.Leu554Met missense_variant 0.51 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 0.52 rifampicin
rpoB 761482 p.Ala559Gly missense_variant 0.53 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.5 rifampicin
rpoB 761496 p.Tyr564Asn missense_variant 0.46 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 0.48 rifampicin
rpoB 761505 p.Ser567Pro missense_variant 0.51 rifampicin Uncertain significance
rpoB 761510 c.1704T>C synonymous_variant 0.5 rifampicin
rpoB 761513 p.Glu569Asp missense_variant 0.5 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 0.48 rifampicin
rpoB 761534 c.1728G>A synonymous_variant 0.47 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>T synonymous_variant 0.49 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.62 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>A synonymous_variant 0.57 rifampicin
rpoB 761636 c.1830G>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>A synonymous_variant 0.52 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 0.51 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.53 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.53 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.55 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.5 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.45 rifampicin
rpoB 761712 p.Val636Ile missense_variant 0.42 rifampicin
rpoB 761718 c.1912_1913delGCinsT frameshift_variant&missense_variant 0.37 rifampicin
rpoB 761722 p.Glu639Gly missense_variant 0.35 rifampicin Uncertain significance
rpoB 761727 p.Ser641Gly missense_variant 0.4 rifampicin
rpoB 761729 c.1925dupG frameshift_variant 0.38 rifampicin
rpoB 761736 p.Ile644Val missense_variant 0.41 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 0.43 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.4 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.39 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.38 rifampicin
rpoB 761783 c.1977C>T synonymous_variant 0.38 rifampicin
rpoB 761784 p.Thr660Ser missense_variant 0.38 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.41 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.54 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.53 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 0.5 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 0.49 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.45 rifampicin
rpoB 761868 p.Asp688Gln missense_variant 0.46 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 0.46 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.52 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.53 rifampicin
rpoB 761892 p.Ile696Val missense_variant 0.53 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.55 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.54 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.52 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.51 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.55 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.57 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.67 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.67 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.8 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.81 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.8 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.82 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.81 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.81 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.72 rifampicin
rpoB 762293 c.2487T>G synonymous_variant 0.7 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.72 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.69 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.6 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.58 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.57 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.56 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.55 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.55 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.55 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.53 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.51 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.51 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.53 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.55 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.52 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762788 c.2982G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.27 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.26 rifampicin
rpoB 762795 p.Asp997Asn missense_variant 0.25 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762814 p.Met1003Thr missense_variant 0.41 rifampicin Uncertain significance
rpoC 762816 c.-554_-552delCTCinsTTG upstream_gene_variant 0.38 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.43 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.7 rifampicin Uncertain significance
rpoC 762911 c.-459C>T upstream_gene_variant 0.77 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.83 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763022 c.-348C>G upstream_gene_variant 0.86 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.89 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.91 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.84 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763160 c.-210G>T upstream_gene_variant 0.79 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.77 rifampicin
rpoC 763193 c.-177C>T upstream_gene_variant 0.69 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.64 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.64 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.61 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 763227 p.Leu1141Met missense_variant 0.53 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.53 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.51 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 0.54 rifampicin
rpoC 763259 c.-111G>T upstream_gene_variant 0.41 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.37 rifampicin
rpoB 763265 c.3459G>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763274 c.-96G>C upstream_gene_variant 0.31 rifampicin
rpoC 763277 c.-93A>T upstream_gene_variant 0.3 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.46 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.46 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.48 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 0.49 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.48 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.51 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 0.59 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.68 rifampicin
rpoC 763492 c.123G>T synonymous_variant 0.69 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.73 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>G synonymous_variant 0.76 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.76 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.7 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 0.68 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.68 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.71 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.71 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.71 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.68 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.68 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.63 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.66 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.66 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.66 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.63 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.63 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.62 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.68 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.67 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.67 rifampicin
rpoC 763884 p.Ala172Val missense_variant 0.32 rifampicin Not assoc w R
rpoC 763886 c.517C>A synonymous_variant 0.32 rifampicin Not assoc w R
rpoC 763891 c.522G>C synonymous_variant 0.65 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.64 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.63 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.63 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.61 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.62 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.63 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.59 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.58 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.56 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.6 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764021 c.652C>A synonymous_variant 0.53 rifampicin
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.5 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.49 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.52 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.57 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.58 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.58 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.56 rifampicin
rpoC 764077 c.708C>G synonymous_variant 0.55 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.54 rifampicin
rpoC 764089 c.720C>G synonymous_variant 0.53 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.51 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.66 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.62 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 0.62 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.58 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 0.58 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.57 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.57 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.57 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.57 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.57 rifampicin
rpoC 764227 c.858G>C synonymous_variant 0.6 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.7 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.7 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.69 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.71 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.72 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.79 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764374 c.1005C>T synonymous_variant 0.77 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.75 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.71 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.69 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 0.69 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.71 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.72 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.68 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764719 c.1350G>A synonymous_variant 0.8 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.81 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764851 c.1482C>T synonymous_variant 0.81 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.78 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.78 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.76 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.75 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.75 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>T synonymous_variant 0.52 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.33 rifampicin
rpoC 765016 c.1647C>A synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765022 c.1653G>C synonymous_variant 0.33 rifampicin
rpoC 765034 c.1665T>C synonymous_variant 0.33 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765070 c.1701G>C synonymous_variant 0.34 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.25 rifampicin
rpoC 765171 p.Pro601Leu missense_variant 1.0 rifampicin Not assoc w R
rpoC 765230 p.Ala621Thr missense_variant 1.0 rifampicin Not assoc w R
rpoC 765338 p.Gln657Lys missense_variant 0.23 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765357 p.Met663Thr missense_variant 0.27 rifampicin
rpoC 765361 c.1992C>G synonymous_variant 0.27 rifampicin
rpoC 765364 p.Glu665Asp missense_variant 0.28 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.42 rifampicin Uncertain significance
rpoC 765403 c.2034G>C synonymous_variant 0.5 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.48 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.51 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.52 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.56 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.61 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.58 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.6 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.6 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765533 p.Tyr722His missense_variant 0.52 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.34 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.35 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.37 rifampicin
rpoC 765577 c.2208G>T synonymous_variant 0.37 rifampicin
rpoC 765591 p.Arg741Gln missense_variant 0.31 rifampicin
rpoC 765596 p.Lys743Gln missense_variant 0.34 rifampicin
rpoC 765709 p.Glu780Asp missense_variant 0.22 rifampicin
rpoC 765718 p.Asp783Glu missense_variant 0.33 rifampicin Uncertain significance
rpoC 765728 p.Gln787Lys missense_variant 0.36 rifampicin
rpoC 765734 p.Leu789Met missense_variant 0.35 rifampicin
rpoC 765737 p.Arg790Glu missense_variant 0.35 rifampicin
rpoC 765743 p.His792Tyr missense_variant 0.39 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.43 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.42 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.56 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 0.54 rifampicin
rpoC 765779 p.Asp804Lys missense_variant 0.54 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.55 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.54 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.55 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.56 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 0.58 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.61 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765868 c.2499G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.71 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.72 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.73 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765895 c.2526G>A synonymous_variant 0.7 rifampicin
rpoC 765899 c.2530C>T synonymous_variant 0.71 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.71 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.71 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.7 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.69 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.69 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.7 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.53 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.5 rifampicin
rpoC 766034 p.His889Thr missense_variant 0.5 rifampicin
rpoC 766039 c.2670C>T synonymous_variant 0.5 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.5 rifampicin
rpoC 766242 p.Thr958Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 766309 c.2940G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.26 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.28 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.36 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.36 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.4 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.41 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.43 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.44 rifampicin
rpoC 766428 c.3059_3060insTAC disruptive_inframe_insertion 0.46 rifampicin
rpoC 766433 c.3065delA frameshift_variant 0.44 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 0.49 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 0.54 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 0.53 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.53 rifampicin Uncertain significance
rpoC 766492 c.3123T>G synonymous_variant 0.53 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 0.53 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.53 rifampicin
rpoC 766517 p.Thr1050Ala missense_variant 0.52 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.51 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.47 rifampicin
rpoC 766539 c.3171_3174delCGGC frameshift_variant 0.42 rifampicin
rpoC 766548 c.3179_3180insACAA frameshift_variant 0.4 rifampicin
rpoC 766554 p.Tyr1062Phe missense_variant 0.39 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.57 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.49 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.52 rifampicin
rpoC 766603 p.Asp1078Glu missense_variant 0.51 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.49 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.57 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.58 rifampicin
rpoC 766634 p.Phe1089Leu missense_variant 0.56 rifampicin
rpoC 766638 p.Lys1090Thr missense_variant 0.55 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.55 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.55 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.51 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 0.52 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.53 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.55 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.55 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.56 rifampicin
rpoC 766694 p.Gln1109Asp missense_variant 0.57 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.63 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.62 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.62 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.65 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.65 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.52 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.52 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.52 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>T synonymous_variant 0.57 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.57 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.54 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.56 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.56 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.56 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.56 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.59 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.56 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.56 rifampicin
rpoC 766931 p.Ala1188Thr missense_variant 0.59 rifampicin Uncertain significance
rpoC 766935 p.Glu1189Ala missense_variant 0.59 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.6 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 0.64 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>T synonymous_variant 0.7 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.66 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.69 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.68 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.7 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.7 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767281 c.3912C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 767302 c.3933C>A synonymous_variant 0.31 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775814 c.2667C>G synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775817 c.2664T>C synonymous_variant 0.27 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.21 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.41 bedaquiline
clofazimine
mmpL5 775862 c.2619G>C synonymous_variant 0.28 bedaquiline
clofazimine
mmpL5 775865 c.2616T>C synonymous_variant 0.31 bedaquiline
clofazimine
mmpL5 775886 c.2595A>C synonymous_variant 0.27 bedaquiline
clofazimine
mmpL5 775895 c.2586C>A synonymous_variant 0.23 bedaquiline
clofazimine
mmpL5 775898 c.2583G>A synonymous_variant 0.24 bedaquiline
clofazimine
mmpL5 775904 c.2577G>A synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 775910 c.2571G>A synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775915 p.Ala856Ser missense_variant 0.26 bedaquiline
clofazimine
mmpL5 775916 c.2565T>C synonymous_variant 0.27 bedaquiline
clofazimine
mmpL5 775937 c.2544G>C synonymous_variant 0.23 bedaquiline
clofazimine
mmpL5 775940 c.2541C>T synonymous_variant 0.27 bedaquiline
clofazimine
mmpL5 775943 c.2538C>G synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775951 c.2530C>T synonymous_variant 0.46 bedaquiline
clofazimine
mmpL5 775955 p.Ile842Val missense_variant 0.24 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.28 bedaquiline
clofazimine
mmpL5 775970 c.2511G>C synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.43 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.44 bedaquiline
clofazimine
mmpL5 775991 c.2490G>A synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 775994 p.Ile829Leu missense_variant 0.31 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.42 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.34 bedaquiline
clofazimine
mmpL5 776003 p.Ile826Leu missense_variant 0.34 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 776018 c.2463G>C synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 776030 c.2451G>T synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 776039 c.2442C>A synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 776048 c.2433G>C synonymous_variant 0.49 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 0.53 bedaquiline
clofazimine
mmpL5 776075 c.2406C>G synonymous_variant 0.53 bedaquiline
clofazimine
mmpL5 776078 c.2403C>A synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 776084 c.2397C>G synonymous_variant 0.48 bedaquiline
clofazimine
mmpL5 776087 c.2394C>G synonymous_variant 0.51 bedaquiline
clofazimine
mmpL5 776096 c.2385C>G synonymous_variant 0.38 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Leu missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776129 c.2352C>G synonymous_variant 0.32 bedaquiline
clofazimine
mmpL5 776716 p.Lys589Gln missense_variant 1.0 bedaquiline
clofazimine
rpsL 781395 c.-165T>C upstream_gene_variant 0.97 streptomycin Not assoc w R
rpsL 781559 c.-1G>C upstream_gene_variant 0.33 streptomycin
rpsL 781572 p.Gln5Asn missense_variant 0.42 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.51 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.52 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.52 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.54 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.59 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.59 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.64 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.6 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.58 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.63 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.62 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.61 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.6 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.59 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.58 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.58 streptomycin
rpsL 781737 p.Gln60Gly missense_variant 0.61 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.61 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.63 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.66 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.68 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.67 streptomycin Not assoc w R - Interim
rpsL 781769 c.210G>A synonymous_variant 0.68 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.74 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.73 streptomycin
rpsL 781829 c.270G>T synonymous_variant 0.75 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.73 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.75 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.74 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.77 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.76 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.76 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.73 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.72 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.72 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.71 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.67 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.62 streptomycin Uncertain significance
rplC 800357 c.-452C>A upstream_gene_variant 1.0 linezolid Not assoc w R
rplC 800516 c.-293G>C upstream_gene_variant 0.23 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.35 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.36 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.41 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.4 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.4 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.4 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.38 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.35 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.35 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.35 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.4 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.44 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.44 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.52 linezolid
rplC 800639 c.-170C>G upstream_gene_variant 0.49 linezolid
rplC 800642 c.-167C>T upstream_gene_variant 0.48 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.49 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.49 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.5 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.54 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.5 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.49 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.5 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.49 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.5 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.47 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.46 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.45 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.48 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.39 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.37 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.34 linezolid
rplC 800904 c.96G>C synonymous_variant 0.21 linezolid
rplC 800921 p.Arg38Leu missense_variant 0.21 linezolid
rplC 800928 c.120C>T synonymous_variant 0.23 linezolid
rplC 800931 c.123G>C synonymous_variant 0.24 linezolid
rplC 800937 c.129A>G synonymous_variant 0.24 linezolid
rplC 800946 c.138T>C synonymous_variant 0.26 linezolid
rplC 800949 c.141T>C synonymous_variant 0.26 linezolid
rplC 800964 c.156G>C synonymous_variant 0.23 linezolid
rplC 800985 c.177A>G synonymous_variant 0.21 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
fbiC 1303785 c.855G>A synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303788 c.858T>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303827 p.Glu299Asp missense_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1303842 p.AlaPhe305SerThr missense_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303866 p.Glu312Asp missense_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303869 c.939T>C synonymous_variant 0.24 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303871 p.Tyr314Phe missense_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303873 p.Leu315Ile missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303882 p.Val318Ile missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303891 p.Ala321Thr missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303896 c.966G>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303897 c.967C>T synonymous_variant 0.23 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303908 c.978C>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1303912 p.Gly328Lys missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>T synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303938 c.1008C>T synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303968 c.1038G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303969 p.Val347Ile missense_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303998 c.1068T>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1304479 c.1549_1551delCTTinsTTG synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304490 c.1560C>G synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304493 c.1563C>T synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304499 c.1569T>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304508 p.Glu526Asp missense_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304511 c.1581C>T synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304517 c.1587C>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304520 c.1590A>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304567 p.Phe546Tyr missense_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1304664 c.1734G>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Ala missense_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304682 c.1752C>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304718 c.1788C>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304727 c.1797A>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>T synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1304760 c.1830G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1304769 c.1839C>T synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304799 c.1869G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304802 c.1872G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
sigE 1364640 c.228G>C synonymous_variant 0.22 pyrazinamide
sigE 1364643 c.231C>T synonymous_variant 0.22 pyrazinamide
sigE 1364649 c.237C>T synonymous_variant 0.22 pyrazinamide
sigE 1364650 p.Thr80Ala missense_variant 0.22 pyrazinamide Uncertain significance
sigE 1364658 c.246G>C synonymous_variant 0.26 pyrazinamide
sigE 1364661 c.249C>A synonymous_variant 0.3 pyrazinamide
sigE 1364667 c.255T>C synonymous_variant 0.38 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.43 pyrazinamide
sigE 1364682 c.270G>A synonymous_variant 0.46 pyrazinamide
sigE 1364688 c.276C>A synonymous_variant 0.45 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.45 pyrazinamide
sigE 1364697 c.285G>A synonymous_variant 0.48 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.5 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 0.5 pyrazinamide
sigE 1364718 c.306C>G synonymous_variant 0.52 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.52 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.53 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 0.61 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.64 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.65 pyrazinamide
sigE 1364778 c.366G>A synonymous_variant 0.67 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 0.67 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.66 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.68 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.65 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.64 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.63 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.64 pyrazinamide
sigE 1364818 c.406_408delCTAinsTTG synonymous_variant 0.67 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.72 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 0.72 pyrazinamide
sigE 1364865 p.Ala152Gly missense_variant 0.71 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 0.71 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
sigE 1364883 c.471G>A synonymous_variant 0.68 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.69 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.65 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.64 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.64 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.65 pyrazinamide
sigE 1364931 c.519C>T synonymous_variant 0.66 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.48 pyrazinamide
sigE 1364956 c.544C>T synonymous_variant 0.45 pyrazinamide
sigE 1364962 p.Pro184Ala missense_variant 0.41 pyrazinamide
sigE 1364967 c.555C>T synonymous_variant 0.4 pyrazinamide
sigE 1364970 c.558G>A synonymous_variant 0.41 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>T synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 0.41 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.41 pyrazinamide
sigE 1364992 p.Pro194Ala missense_variant 0.42 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.42 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.43 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.43 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.41 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.38 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.3 pyrazinamide
sigE 1365048 c.636G>A synonymous_variant 0.29 pyrazinamide
embR 1417019 p.Cys110Tyr missense_variant 1.0 ethambutol Not assoc w R
embR 1417554 c.-207C>G upstream_gene_variant 1.0 ethambutol
embR 1417793 c.-446C>T upstream_gene_variant 1.0 ethambutol
atpE 1461137 c.93C>G synonymous_variant 0.33 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.33 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.32 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.3 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.3 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.35 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.33 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.33 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.38 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.37 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.36 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.36 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 0.3 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.26 bedaquiline
rrs 1471508 n.-338T>C upstream_gene_variant 0.3 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471517 n.-329T>C upstream_gene_variant 0.29 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.35 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.61 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.72 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472037 n.192A>C non_coding_transcript_exon_variant 0.68 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.8 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.72 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 0.72 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.8 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.78 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.81 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.79 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1473830 n.173T>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.68 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474022 n.365G>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474044 n.387C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1474045 n.388C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1474053 n.396G>A non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474102 n.445_446insTGAAC non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474106 n.449_453delATCAAinsG non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_635delTCCTTTinsCTCGACTTG non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474421 n.764_767delGCGCinsA non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAAT non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475382 n.1725A>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475394 n.1738delT non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475400 n.1743C>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid Uncertain significance
rrl 1475401 n.1744A>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475402 n.1745C>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.89 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
inhA 1673607 c.-595T>C upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673615 c.-587_-586delAAinsTG upstream_gene_variant 0.37 isoniazid
ethionamide
inhA 1673619 c.-583T>C upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1673633 c.-569G>A upstream_gene_variant 0.39 isoniazid
ethionamide
inhA 1673637 c.-565C>G upstream_gene_variant 0.37 isoniazid
ethionamide
inhA 1673646 c.-556T>C upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673652 c.-550C>G upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673657 c.-545_-544delCGinsAA upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 0.35 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 0.49 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsCA upstream_gene_variant 0.48 isoniazid
ethionamide
inhA 1673721 c.-481C>T upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 0.51 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.52 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.51 isoniazid
ethionamide
inhA 1673760 c.-442G>C upstream_gene_variant 0.53 isoniazid
ethionamide
inhA 1673769 c.-433C>T upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673784 c.-418G>A upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673787 c.-415G>A upstream_gene_variant 0.49 isoniazid Uncertain significance
ethionamide
inhA 1673799 c.-403T>G upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 0.47 isoniazid
ethionamide
inhA 1673808 c.-394A>C upstream_gene_variant 0.46 isoniazid
ethionamide
inhA 1673811 c.-391G>A upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673829 c.-373C>G upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1673830 c.-372_-370delAAAinsCGT upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 0.37 isoniazid
ethionamide
inhA 1673841 c.-361A>C upstream_gene_variant 0.37 isoniazid
ethionamide
inhA 1673844 c.-358G>C upstream_gene_variant 0.37 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673853 c.-349A>C upstream_gene_variant 0.42 isoniazid
ethionamide
inhA 1673870 c.-332_-331delGCinsTG upstream_gene_variant 0.51 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 0.56 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.56 isoniazid
ethionamide
inhA 1673916 c.-286A>C upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.48 isoniazid
ethionamide
inhA 1673925 c.-277C>T upstream_gene_variant 0.48 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673931 c.-271C>G upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 0.49 isoniazid
ethionamide
inhA 1673946 c.-256C>G upstream_gene_variant 0.49 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.47 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.44 isoniazid
ethionamide
inhA 1673962 c.-240_-239delAAinsGG upstream_gene_variant 0.44 isoniazid
ethionamide
inhA 1673967 c.-235G>C upstream_gene_variant 0.43 isoniazid
ethionamide
inhA 1673973 c.-229G>C upstream_gene_variant 0.42 isoniazid Uncertain significance
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 0.42 isoniazid
ethionamide
inhA 1673991 c.-211C>T upstream_gene_variant 0.44 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 0.4 isoniazid
ethionamide
inhA 1674018 c.-184G>C upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1674123 c.-79T>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1674465 c.264C>G synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674471 c.270G>C synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674477 c.276G>C synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.49 isoniazid
ethionamide
inhA 1674489 c.288G>C synonymous_variant 0.53 isoniazid
ethionamide
inhA 1674513 c.312C>T synonymous_variant 0.57 isoniazid
ethionamide
inhA 1674514 p.Ile105Val missense_variant 0.57 isoniazid
ethionamide
inhA 1674534 c.333G>C synonymous_variant 0.59 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674537 c.336C>T synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.55 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.55 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 0.51 isoniazid
ethionamide
inhA 1674573 c.372G>T synonymous_variant 0.57 isoniazid
ethionamide
inhA 1674579 c.378G>C synonymous_variant 0.57 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.53 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.5 isoniazid
ethionamide
inhA 1674601 p.Leu134Thr missense_variant 0.47 isoniazid
ethionamide
inhA 1674619 p.Pro140Glu missense_variant 0.42 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674628 c.427_428delTCinsAG synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674651 c.450C>T synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 0.46 isoniazid
ethionamide
inhA 1674660 c.459G>T synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674687 c.486G>C synonymous_variant 0.37 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 0.36 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.39 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.41 isoniazid
ethionamide
inhA 1674762 c.561T>C synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674765 c.564C>T synonymous_variant 0.41 isoniazid
ethionamide
inhA 1674771 c.570C>G synonymous_variant 0.43 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.43 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.52 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674795 c.594G>C synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674827 p.Glu209Ala missense_variant 0.49 isoniazid
ethionamide
inhA 1674831 c.630G>A synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674837 c.636C>T synonymous_variant 0.47 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674839 p.Ala213Asp missense_variant 0.5 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.56 isoniazid
ethionamide
inhA 1674848 p.Gln216Arg missense_variant 0.54 isoniazid Uncertain significance
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.52 isoniazid
ethionamide
inhA 1674876 c.675C>T synonymous_variant 0.57 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 0.56 isoniazid
ethionamide
inhA 1674883 p.Ile228Val missense_variant 0.55 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674903 c.702T>C synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.51 isoniazid
ethionamide
inhA 1674907 p.Thr236Glu missense_variant 0.5 isoniazid
ethionamide
inhA 1674918 c.717C>G synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674924 c.723G>C synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674933 c.732G>A synonymous_variant 0.44 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674939 c.738G>T synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674954 c.753G>C synonymous_variant 0.3 isoniazid
ethionamide
inhA 1674957 c.756G>C synonymous_variant 0.26 isoniazid
ethionamide
inhA 1674963 c.762G>C synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674966 c.765T>C synonymous_variant 0.24 isoniazid
ethionamide
inhA 1674967 p.Asp256Thr missense_variant 0.24 isoniazid
ethionamide
inhA 1674973 p.Ile258Val missense_variant 0.23 isoniazid
ethionamide
rpsA 1833589 c.48A>C synonymous_variant 0.34 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.36 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.36 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.47 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.46 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.51 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.56 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.64 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.64 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.66 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.67 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.69 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.69 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.69 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.7 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.67 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.67 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.65 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.66 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.65 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.68 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.74 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.73 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.73 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.72 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.72 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.7 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.73 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.72 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.73 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.74 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.74 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.74 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.74 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.77 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.77 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.74 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.74 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.74 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.73 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.72 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.7 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.7 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.72 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.68 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.63 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.64 pyrazinamide
rpsA 1834168 c.627C>T synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 0.65 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.7 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.7 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.69 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.72 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.7 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.69 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.69 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.71 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.71 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.68 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.67 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.68 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.73 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.68 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.72 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.72 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.61 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.59 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.59 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.6 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.6 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.47 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.47 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.47 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.46 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.46 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 0.56 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 0.56 pyrazinamide
rpsA 1834829 p.Ala430Thr missense_variant 0.48 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.52 linezolid
tsnR 1853375 c.-231G>A upstream_gene_variant 0.51 linezolid
tsnR 1853384 c.-222G>T upstream_gene_variant 0.56 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.59 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.6 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.57 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.52 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.51 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.44 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.39 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.37 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.33 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.33 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.34 linezolid
tsnR 1853474 c.-132C>G upstream_gene_variant 0.35 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.37 linezolid
tsnR 1853480 c.-126G>C upstream_gene_variant 0.38 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 0.38 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.38 linezolid
tsnR 1853490 c.-116_-114delCCGinsGCC upstream_gene_variant 0.38 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.37 linezolid
tsnR 1853974 c.369C>T synonymous_variant 1.0 linezolid Not assoc w R
tsnR 1854045 p.Tyr147Cys missense_variant 1.0 linezolid Not assoc w R
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2062922 p.Ile603Val missense_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Not assoc w R
amikacin Not assoc w R
ndh 2102610 c.433T>C synonymous_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2102638 c.405A>C synonymous_variant 0.46 isoniazid
delamanid
ethionamide
katG 2154724 p.Arg463Leu missense_variant 0.92 isoniazid Not assoc w R
katG 2155680 c.432G>C synonymous_variant 0.26 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.31 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.37 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.41 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.41 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.38 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.36 isoniazid
katG 2155747 p.Ala122Gly missense_variant 0.31 isoniazid
katG 2155752 c.360C>T synonymous_variant 0.32 isoniazid
katG 2155764 p.His116Glu missense_variant 0.31 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.33 isoniazid
katG 2155779 c.333C>T synonymous_variant 0.32 isoniazid
katG 2155782 c.330C>G synonymous_variant 0.31 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.32 isoniazid
katG 2155794 p.Ala106Ser missense_variant 0.32 isoniazid
katG 2155800 c.312G>C synonymous_variant 0.3 isoniazid
katG 2155805 p.Ile103Val missense_variant 0.27 isoniazid Uncertain significance
katG 2155806 c.306T>C synonymous_variant 0.27 isoniazid
katG 2155815 c.297G>T synonymous_variant 0.24 isoniazid Not assoc w R - Interim
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
PPE35 2167983 p.Gly877Asp missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517941 c.-174C>G upstream_gene_variant 0.57 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.53 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.52 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.51 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.51 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 0.57 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.56 isoniazid
kasA 2518013 c.-102G>A upstream_gene_variant 0.37 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.26 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.28 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.3 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.3 isoniazid
kasA 2518639 c.525G>T synonymous_variant 0.31 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.31 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.31 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 0.3 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.3 isoniazid
kasA 2518726 c.612G>C synonymous_variant 0.48 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.53 isoniazid
kasA 2518738 c.624G>A synonymous_variant 0.55 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.49 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.56 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.49 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.46 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.45 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.45 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.47 isoniazid
kasA 2518796 c.682C>A synonymous_variant 0.48 isoniazid
kasA 2518813 c.699C>T synonymous_variant 0.57 isoniazid
kasA 2518819 c.705C>T synonymous_variant 0.57 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.56 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.54 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.55 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.54 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.49 isoniazid
kasA 2518873 c.759C>T synonymous_variant 0.4 isoniazid
kasA 2518877 p.Lys255Leu missense_variant 0.37 isoniazid
kasA 2518882 c.768C>T synonymous_variant 0.39 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.38 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 0.44 isoniazid
kasA 2519209 c.1095C>G synonymous_variant 0.42 isoniazid
kasA 2519212 c.1098C>G synonymous_variant 0.43 isoniazid
kasA 2519218 c.1104G>C synonymous_variant 0.48 isoniazid
kasA 2519224 c.1110C>G synonymous_variant 0.52 isoniazid
kasA 2519242 c.1128C>G synonymous_variant 0.52 isoniazid
kasA 2519306 p.Val398Ile missense_variant 0.42 isoniazid
kasA 2519329 c.1215C>T synonymous_variant 0.38 isoniazid
ahpC 2726051 c.-142G>A upstream_gene_variant 0.97 isoniazid
ahpC 2726657 c.465A>G synonymous_variant 0.22 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 0.22 isoniazid
ahpC 2726684 c.492G>T synonymous_variant 0.21 isoniazid
Rv2477c 2782483 c.1560G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.31 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782534 c.1509C>T synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782555 p.Ser496Thr missense_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.36 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783038 p.Ala335Thr missense_variant 0.35 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783047 p.Asp332Glu missense_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.4 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>T synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783536 c.507G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.43 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783560 c.483C>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783602 c.441G>A synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783626 p.Ala139Ser missense_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783662 c.381G>A synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783671 p.Arg124His missense_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783695 c.348C>T synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783704 c.339C>T synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2681 2996338 c.-401C>A upstream_gene_variant 0.3 capreomycin
Rv2681 2996350 c.-389C>G upstream_gene_variant 0.3 capreomycin
Rv2681 2996354 c.-385C>T upstream_gene_variant 0.31 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.29 capreomycin
Rv2680 2996366 p.Tyr88His missense_variant 0.28 capreomycin
Rv2681 2996374 c.-365G>C upstream_gene_variant 0.29 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 0.29 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 0.29 capreomycin
Rv2680 2996386 p.Asp94Glu missense_variant 0.29 capreomycin
Rv2681 2996389 c.-350A>C upstream_gene_variant 0.31 capreomycin
Rv2681 2996398 c.-341C>A upstream_gene_variant 0.36 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.37 capreomycin
Rv2680 2996404 p.Ile100Met missense_variant 0.4 capreomycin
Rv2681 2996407 c.-332C>G upstream_gene_variant 0.4 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.36 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.33 capreomycin
Rv2681 2997270 p.Ala178Thr missense_variant 0.97 capreomycin
Rv2752c 3064632 c.1560C>T synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
Rv2752c 3065013 c.1179G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065016 c.1176C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065022 c.1170G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065058 c.1134C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065061 c.1131C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065064 c.1128G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCGT synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065115 c.1077C>G synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065126 p.Ser356Ala missense_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065133 c.1059T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065142 c.1050A>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.54 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065154 c.1038G>A synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065166 c.1026C>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065178 c.1014G>A synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065181 c.1011G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065186 c.1006T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065187 p.Val335Ile missense_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065193 c.999C>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065199 c.993T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065202 c.990T>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065205 c.987T>G synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065210 c.982T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065229 c.963G>T synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065612 p.Thr194Ala missense_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065637 c.555A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066288 c.-97G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067391 c.555G>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067415 c.531C>T synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067442 c.502_504delCGCinsAGA synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067457 c.489C>T synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067463 p.Ile161Val missense_variant 0.43 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067500 p.Lys149Arg missense_variant 0.42 para-aminosalicylic_acid
thyX 3067502 p.Ala148Asp missense_variant 0.42 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.39 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067680 p.Cys89Ala missense_variant 0.32 para-aminosalicylic_acid
thyX 3067688 c.258G>A synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067698 p.Thr83Ser missense_variant 0.33 para-aminosalicylic_acid
thyX 3067702 p.Ile82Val missense_variant 0.3 para-aminosalicylic_acid
thyX 3067709 c.237G>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067724 c.222G>A synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067760 c.186G>C synonymous_variant 0.23 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
Rv3083 3448714 p.Asp71His missense_variant 1.0 ethionamide Uncertain significance
lpqB 3624053 c.858C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624060 p.Ala284Val missense_variant 0.33 rifampicin
bedaquiline
lpqB 3624080 p.Arg277Ser missense_variant 0.41 rifampicin
bedaquiline
lpqB 3624086 p.Asp275Gly missense_variant 0.42 rifampicin
bedaquiline
lpqB 3624094 c.817A>C synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3624095 p.Ala272Ser missense_variant 0.42 rifampicin
bedaquiline
lpqB 3624100 c.811T>C synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3624125 c.784_786delTTAinsCTG synonymous_variant 0.49 rifampicin
bedaquiline
lpqB 3624152 c.759C>G synonymous_variant 0.32 rifampicin
bedaquiline
lpqB 3624155 c.756G>C synonymous_variant 0.31 rifampicin
bedaquiline
lpqB 3624486 p.Asp142Gly missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3625623 p.Thr331Ala missense_variant 0.35 rifampicin
bedaquiline
mtrB 3625636 p.Ala326Glu missense_variant 0.4 rifampicin
bedaquiline
mtrB 3625645 c.969C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625648 p.Tyr322His missense_variant 0.38 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625657 c.-747C>T upstream_gene_variant 0.4 rifampicin
bedaquiline
lpqB 3625663 c.-753G>C upstream_gene_variant 0.42 rifampicin
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.41 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.5 rifampicin
bedaquiline
lpqB 3625690 c.-780T>G upstream_gene_variant 0.53 rifampicin
bedaquiline
lpqB 3625696 c.-786A>G upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3625699 c.915C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625735 c.879C>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625741 c.-831G>A upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625753 p.Ala287Gln missense_variant 0.64 rifampicin
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625768 c.-858G>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625771 c.843C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625801 c.-891G>C upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625828 c.-918G>A upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626843 c.-230G>A upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626849 c.-236C>T upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrB 3626885 c.-272A>G upstream_gene_variant 0.22 rifampicin
bedaquiline
mtrB 3626894 c.-281C>T upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrA 3626908 p.Asn148His missense_variant 0.21 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrA 3626962 p.Met130Leu missense_variant 0.34 rifampicin
bedaquiline
mtrA 3626969 c.381C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrA 3626978 p.Asp124Glu missense_variant 0.43 rifampicin Uncertain significance
bedaquiline
mtrB 3626999 c.-386G>C upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627023 c.-410C>G upstream_gene_variant 0.51 rifampicin
bedaquiline
mtrA 3627041 p.Ile103Val missense_variant 0.45 rifampicin
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrB 3627086 c.-473C>G upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrB 3627110 c.-497G>C upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627134 c.-521C>T upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3627137 c.-526_-524delTTGinsCTC upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3627158 c.-545C>G upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.45 rifampicin
bedaquiline
fbiA 3640390 c.-153A>C upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
alr 3841253 c.168C>T synonymous_variant 1.0 cycloserine
rpoA 3877534 p.Val325Ala missense_variant 0.2 rifampicin
rpoA 3877560 c.948C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 0.23 rifampicin
rpoA 3877569 p.Pro313Ala missense_variant 0.24 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.42 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.61 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.6 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.61 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.59 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.61 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.61 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.63 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.64 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877770 c.735_738delGTCAinsCAGC synonymous_variant 0.7 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.64 rifampicin
rpoA 3877797 c.711G>C synonymous_variant 0.67 rifampicin
rpoA 3877803 c.705G>C synonymous_variant 0.69 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877833 c.675C>G synonymous_variant 0.69 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.69 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.67 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877878 c.630G>A synonymous_variant 0.67 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.66 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.64 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877965 c.543C>G synonymous_variant 0.63 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.64 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.53 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>C synonymous_variant 0.48 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878010 c.498C>G synonymous_variant 0.42 rifampicin
rpoA 3878019 c.489A>G synonymous_variant 0.36 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.34 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.34 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.35 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.35 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.33 rifampicin
rpoA 3878037 c.471C>T synonymous_variant 0.33 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>C synonymous_variant 0.33 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.34 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.35 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.41 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.52 rifampicin
rpoA 3878079 c.429C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>C synonymous_variant 0.61 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.64 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.64 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 0.6 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.6 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.65 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.65 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.67 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.69 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.64 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.71 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.68 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.67 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.64 rifampicin Uncertain significance
rpoA 3878298 c.210A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 0.49 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.46 rifampicin
rpoA 3878352 c.156C>G synonymous_variant 0.43 rifampicin
rpoA 3878358 c.150C>G synonymous_variant 0.39 rifampicin
rpoA 3878361 c.147G>A synonymous_variant 0.35 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.35 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.37 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.36 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.37 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.38 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3878400 c.108T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878403 c.105C>T synonymous_variant 0.36 rifampicin
rpoA 3878409 c.99C>G synonymous_variant 0.36 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.35 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.31 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.31 rifampicin
rpoA 3878433 c.75G>C synonymous_variant 0.26 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.26 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.24 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.33 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 0.35 rifampicin
rpoA 3878886 c.-379G>A upstream_gene_variant 0.33 rifampicin Uncertain significance
rpoA 3878890 c.-383C>G upstream_gene_variant 0.35 rifampicin
rpoA 3878893 c.-388_-386delCACinsAAG upstream_gene_variant 0.36 rifampicin
rpoA 3878896 c.-389G>C upstream_gene_variant 0.36 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.36 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.38 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.36 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.36 rifampicin
rpoA 3878935 c.-428C>T upstream_gene_variant 0.38 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.4 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.36 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 0.36 rifampicin
ddn 3986615 c.-229C>A upstream_gene_variant 0.32 pretomanid
delamanid
ddn 3986616 c.-228_-227delAGinsGC upstream_gene_variant 0.32 pretomanid
delamanid
ddn 3986622 c.-222C>T upstream_gene_variant 0.33 pretomanid
delamanid
ddn 3986633 c.-211C>G upstream_gene_variant 0.29 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.29 pretomanid
delamanid
ddn 3986646 c.-198_-196delCTCinsTTG upstream_gene_variant 0.26 pretomanid
delamanid
ddn 3986655 c.-189A>T upstream_gene_variant 0.26 pretomanid
delamanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.24 pretomanid
delamanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.25 pretomanid
delamanid
ddn 3986687 c.-157C>T upstream_gene_variant 0.24 pretomanid
delamanid
clpC1 4038356 c.2349T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.31 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.34 pyrazinamide
clpC1 4038383 c.2322G>C synonymous_variant 0.37 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.37 pyrazinamide
clpC1 4038395 c.2310C>G synonymous_variant 0.34 pyrazinamide
clpC1 4038398 c.2307G>A synonymous_variant 0.33 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCTC synonymous_variant 0.33 pyrazinamide
clpC1 4038410 c.2295C>T synonymous_variant 0.33 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.35 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.37 pyrazinamide
clpC1 4038434 c.2271G>C synonymous_variant 0.37 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.38 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.41 pyrazinamide
clpC1 4038456 p.Val750Gln missense_variant 0.38 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.42 pyrazinamide
clpC1 4038462 p.Ala748Glu missense_variant 0.39 pyrazinamide
clpC1 4038474 p.Ser744Val missense_variant 0.41 pyrazinamide
clpC1 4038479 c.2226C>G synonymous_variant 0.39 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.42 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.42 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.5 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.58 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.52 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.52 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.51 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.57 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.58 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.61 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.64 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.68 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.68 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.68 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.69 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.68 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.69 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.69 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 0.69 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.69 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.73 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.75 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 0.72 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.71 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.69 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.73 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.71 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.7 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.7 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.7 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.71 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.71 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.76 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4038884 c.1821C>T synonymous_variant 0.85 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.83 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.82 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.81 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.82 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.83 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.82 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.81 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4038977 c.1728G>A synonymous_variant 0.77 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.77 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.76 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.75 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.78 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 0.77 pyrazinamide
clpC1 4039109 c.1596C>T synonymous_variant 0.76 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.78 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.76 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.75 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.73 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.75 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 0.7 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>T synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4039283 c.1422C>T synonymous_variant 0.66 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.64 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.65 pyrazinamide
clpC1 4039320 p.Ala462Gly missense_variant 0.68 pyrazinamide
clpC1 4039328 c.1377A>T synonymous_variant 0.63 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 0.64 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.63 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.63 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.6 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.57 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.59 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.57 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.54 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.56 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.54 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.56 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.55 pyrazinamide
clpC1 4039472 c.1233G>T synonymous_variant 0.55 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.55 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.54 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.53 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.59 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.59 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.58 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.58 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.68 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039652 c.1053G>A synonymous_variant 0.72 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.75 pyrazinamide
clpC1 4039685 c.1020C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039694 c.1011G>T synonymous_variant 0.76 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.75 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.71 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.73 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.76 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.75 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.75 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039934 c.771G>T synonymous_variant 0.84 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.84 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.78 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 0.76 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.73 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.74 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.58 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.57 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.48 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.48 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.48 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.47 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.47 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.48 pyrazinamide
clpC1 4040195 c.510G>C synonymous_variant 0.41 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.39 pyrazinamide
clpC1 4040201 c.504C>T synonymous_variant 0.38 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.38 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.38 pyrazinamide
clpC1 4040213 p.Ser164Asn missense_variant 0.4 pyrazinamide
clpC1 4040219 c.486C>T synonymous_variant 0.42 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.47 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.47 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.5 pyrazinamide
clpC1 4040243 c.462C>T synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4040249 c.456A>G synonymous_variant 0.57 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 0.57 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.5 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040306 c.399G>C synonymous_variant 0.49 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
clpC1 4040324 c.381G>C synonymous_variant 0.49 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.54 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.53 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.53 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.55 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.49 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 0.49 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.48 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.49 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.51 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.49 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.52 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.52 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.6 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.56 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.56 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.56 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.56 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>T synonymous_variant 0.62 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>A synonymous_variant 0.68 pyrazinamide
clpC1 4040495 c.210C>G synonymous_variant 0.69 pyrazinamide
clpC1 4040517 p.Val63Ala missense_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.68 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.68 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.65 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.62 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.6 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.56 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.56 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.57 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.57 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.56 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.56 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.56 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.55 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.58 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.6 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.57 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.53 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
panD 4044165 c.117G>C synonymous_variant 0.33 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
panD 4044180 p.Asp34Glu missense_variant 0.36 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.36 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.36 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.36 pyrazinamide
glpK 4138377 p.Val460Ala missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
streptomycin Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
glpK 4138535 c.1221T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138565 c.1191G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138568 c.1188A>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138583 c.1173G>T synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138598 c.1158G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138601 c.1155G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138607 c.1149G>A synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138616 p.Ala380Val missense_variant 0.55 levofloxacin
moxifloxacin
isoniazid Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138622 c.1134C>G synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138625 c.1131G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138631 c.1125C>G synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138643 c.1113A>C synonymous_variant 0.6 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138646 c.1110G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138661 c.1095T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138676 c.1080T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 0.67 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138696 p.Pro354Ala missense_variant 0.64 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138697 c.1059C>G synonymous_variant 0.63 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138703 c.1053C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138709 c.1047G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138727 c.1029C>G synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138775 c.981C>T synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138784 c.972G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138799 c.957T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138802 c.954G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4240717 c.855T>C synonymous_variant 0.5 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4240729 c.867C>G synonymous_variant 0.5 ethambutol
embC 4240735 c.873C>A synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4240738 c.876C>G synonymous_variant 0.5 ethambutol
embC 4240759 c.897C>G synonymous_variant 0.55 ethambutol
embC 4240777 c.915G>A synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.51 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.53 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.51 ethambutol
embC 4240819 c.957A>T synonymous_variant 0.41 ethambutol
embC 4240825 c.963G>A synonymous_variant 0.42 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.42 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.41 ethambutol
embC 4241042 p.Asn394Asp missense_variant 0.82 ethambutol Not assoc w R
embC 4241053 c.1191G>C synonymous_variant 0.23 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.24 ethambutol
embC 4241074 c.1212G>C synonymous_variant 0.26 ethambutol
embC 4241077 c.1215C>T synonymous_variant 0.74 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.27 ethambutol
embC 4241194 c.1332C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241560 c.1698C>G synonymous_variant 0.27 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.32 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.31 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.41 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.42 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.35 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.31 ethambutol
embC 4241648 c.1786T>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
embC 4241656 c.1794G>A synonymous_variant 0.33 ethambutol
embC 4241662 c.1800G>C synonymous_variant 0.32 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.32 ethambutol
embC 4241671 c.1809T>G synonymous_variant 0.33 ethambutol
embC 4241677 c.1815G>A synonymous_variant 0.35 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4242844 c.-389A>G upstream_gene_variant 0.38 ethambutol
embA 4242856 c.-377C>T upstream_gene_variant 0.38 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.36 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 0.36 ethambutol
embC 4242872 p.Asp1004Thr missense_variant 0.36 ethambutol
embC 4242878 p.Thr1006Val missense_variant 0.38 ethambutol
embA 4242907 c.-326G>C upstream_gene_variant 0.38 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.31 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embA 4242940 c.-293T>C upstream_gene_variant 0.26 ethambutol
embC 4242941 p.His1027Tyr missense_variant 0.21 ethambutol
embA 4243848 p.Val206Met missense_variant 1.0 ethambutol Not assoc w R
embA 4245762 p.Gly844Lys missense_variant 0.33 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.35 ethambutol
embA 4245774 p.Leu848Val missense_variant 0.35 ethambutol
embA 4245784 p.Thr851Lys missense_variant 0.35 ethambutol
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.28 ethambutol
embA 4245820 p.Ser863Thr missense_variant 0.22 ethambutol
embA 4245969 p.Pro913Ser missense_variant 1.0 ethambutol Not assoc w R
embB 4246172 c.-342C>T upstream_gene_variant 1.0 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.23 ethambutol
embB 4247437 c.924A>C synonymous_variant 0.24 ethambutol
embB 4247440 c.927C>G synonymous_variant 0.23 ethambutol
embB 4247449 c.936C>T synonymous_variant 0.28 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.35 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.36 ethambutol
embB 4247488 c.975C>T synonymous_variant 0.41 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.42 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.42 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 0.38 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.41 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.28 ethambutol
embB 4247555 p.Leu348Ile missense_variant 0.27 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.29 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.27 ethambutol
embB 4247579 p.Ala356Ile missense_variant 0.24 ethambutol
embB 4247582 p.Ala357Cys missense_variant 0.23 ethambutol
embB 4247586 p.Gly358Ala missense_variant 0.21 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embB 4247593 c.1080G>C synonymous_variant 0.22 ethambutol
embB 4247611 c.1098G>C synonymous_variant 0.22 ethambutol
embB 4247614 c.1101T>C synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
embB 4248007 c.1494C>G synonymous_variant 0.31 ethambutol
embB 4248011 p.Ser500Ala missense_variant 0.31 ethambutol
embB 4248016 c.1503G>A synonymous_variant 0.31 ethambutol
embB 4248020 c.1507T>C synonymous_variant 0.34 ethambutol
embB 4248025 c.1512A>G synonymous_variant 0.32 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.29 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.29 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.29 ethambutol
embB 4248052 c.1539G>C synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embB 4248063 p.Ala517Glu missense_variant 0.3 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.29 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.28 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.27 ethambutol
embB 4248106 c.1593C>G synonymous_variant 0.27 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.26 ethambutol
embB 4248121 c.1608G>A synonymous_variant 0.24 ethambutol
embB 4248127 c.1614G>A synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embB 4248130 c.1617G>C synonymous_variant 0.22 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.22 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.21 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.3 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.31 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.32 ethambutol Uncertain significance
embB 4248220 c.1707A>G synonymous_variant 0.34 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.33 ethambutol Uncertain significance
embB 4248242 p.Val577Ile missense_variant 0.29 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.28 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.3 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.33 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.21 ethambutol
aftB 4269143 c.-307T>C upstream_gene_variant 0.22 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.24 ethambutol Not assoc w R - Interim
ubiA 4269149 p.Val229Met missense_variant 0.3 ethambutol
aftB 4269171 c.-335C>G upstream_gene_variant 0.32 ethambutol
aftB 4269177 c.-341G>C upstream_gene_variant 0.32 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.33 ethambutol
ubiA 4269187 p.Thr216Ser missense_variant 0.33 ethambutol Uncertain significance
aftB 4269192 c.-356C>G upstream_gene_variant 0.34 ethambutol
aftB 4269198 c.-362C>T upstream_gene_variant 0.34 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.36 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.39 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.39 ethambutol Not assoc w R - Interim
aftB 4269225 c.-389C>G upstream_gene_variant 0.38 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 0.39 ethambutol
aftB 4269242 c.-406C>T upstream_gene_variant 0.39 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.4 ethambutol
aftB 4269255 c.-419C>T upstream_gene_variant 0.43 ethambutol
aftB 4269258 c.-422C>T upstream_gene_variant 0.43 ethambutol
aftB 4269264 c.-428C>A upstream_gene_variant 0.4 ethambutol
ubiA 4269270 p.Val188Ala missense_variant 0.42 ethambutol Uncertain significance
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338429 c.-218_92del frameshift_variant&start_lost 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407780 c.423G>A synonymous_variant 1.0 streptomycin Not assoc w R - Interim
gid 4407873 c.330G>T synonymous_variant 1.0 streptomycin Not assoc w R