Run ID: SRR3675517
Sample name:
Date: 2024-04-15T15:10:26.783722
Number of reads: 1097740
Percentage reads mapped: 17.42
Median coverage: 28.0
Strain: La3;lineage2.1;lineage4.9;lineage6.3
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage6.3 | West-Africa 2 | RD702 | 0.05 |
| lineage4.1.2.1.1 | Euro-American (Haarlem) | RD182 | 0.09 |
| La1.2.BCG | M.bovis | None | 0.16 |
| lineage4 | Euro-American | None | 0.87 |
| lineage2.1 | East-Asian (non-Beijing) | None | 0.07 |
| lineage6.2.3 | West-Africa 2 | RD702 | 0.1 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.81 |
| La3 | M.orygis | None | 0.19 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.His312Arg | Mutation from literature | |
| p.Ala388Gly | Mutation from literature | |||
| p.Asn399Asp | Mutation from literature | |||
| pyrazinamide | panD | p.Val138Ala | Mutation from literature | |
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | tlyA | c.319_321delCACinsGA | Assoc w R | |
| c.376_378delCCTinsGG | Assoc w R | |||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.202_204delCTGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.412_414delCTAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiC | c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 490984 | c.202_204delCTGinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491194 | c.412_414delCTAinsTG | frameshift_variant&stop_gained | 0.68 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| tlyA | 1918258 | c.319_321delCACinsGA | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
| tlyA | 1918315 | c.376_378delCCTinsGG | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
| panD | 4043869 | p.Val138Ala | missense_variant | 1.0 | pyrazinamide | Mutation from literature | |
| embB | 4247448 | p.His312Arg | missense_variant | 0.96 | ethambutol | Mutation from literature | |
| embB | 4247676 | p.Ala388Gly | missense_variant | 1.0 | ethambutol | Mutation from literature | |
| embB | 4247708 | p.Asn399Asp | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 30 | c.30C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 42 | c.42C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 51 | c.51C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 510 | c.510T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 519 | c.519C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
| dnaA | 522 | c.522T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 525 | c.525T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 534 | c.534T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 558 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 561 | c.561C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 567 | c.567C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 571 | c.571T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 612 | c.612G>C | synonymous_variant | 0.65 | isoniazid | |
| dnaA | 627 | c.627G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 645 | c.645A>C | synonymous_variant | 0.65 | isoniazid | Not assoc w R - Interim |
| dnaA | 649 | c.649C>T | synonymous_variant | 0.6 | isoniazid | Not assoc w R - Interim |
| dnaA | 654 | c.654A>G | synonymous_variant | 0.61 | isoniazid | |
| dnaA | 660 | c.660G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 663 | c.663A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 669 | c.669C>T | synonymous_variant | 0.59 | isoniazid | |
| dnaA | 672 | c.672T>C | synonymous_variant | 0.59 | isoniazid | Not assoc w R - Interim |
| dnaA | 678 | c.678A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 681 | c.681G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 693 | c.693A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 705 | c.705A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 714 | c.714C>T | synonymous_variant | 0.44 | isoniazid | |
| dnaA | 720 | c.720G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 747 | c.747G>T | synonymous_variant | 0.48 | isoniazid | |
| dnaA | 748 | c.748_750delCTCinsTG | frameshift_variant&missense_variant | 0.48 | isoniazid | Uncertain significance |
| dnaA | 756 | c.756T>C | synonymous_variant | 0.49 | isoniazid | |
| dnaA | 763 | p.Lys255Arg | missense_variant | 0.51 | isoniazid | |
| dnaA | 768 | c.768C>G | synonymous_variant | 0.43 | isoniazid | |
| dnaA | 771 | c.771A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 786 | c.786C>T | synonymous_variant | 0.42 | isoniazid | |
| dnaA | 793 | c.793_795delGTAinsAC | frameshift_variant&missense_variant | 0.56 | isoniazid | Uncertain significance |
| dnaA | 801 | c.801G>T | synonymous_variant | 0.55 | isoniazid | |
| dnaA | 804 | c.804G>C | synonymous_variant | 0.55 | isoniazid | |
| dnaA | 805 | c.805_807delTTGinsCC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 813 | c.813C>T | synonymous_variant | 0.46 | isoniazid | |
| dnaA | 819 | c.819C>T | synonymous_variant | 0.43 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 837 | c.837A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 0.61 | isoniazid | Not assoc w R - Interim |
| dnaA | 882 | c.882C>T | synonymous_variant | 0.36 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 888 | c.888C>G | synonymous_variant | 0.59 | isoniazid | |
| dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 903 | c.903C>G | synonymous_variant | 0.56 | isoniazid | Not assoc w R - Interim |
| dnaA | 909 | c.909A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 912 | c.912T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 918 | c.918C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 921 | c.921A>G | synonymous_variant | 0.56 | isoniazid | Not assoc w R - Interim |
| dnaA | 924 | c.924C>G | synonymous_variant | 0.44 | isoniazid | |
| dnaA | 928 | p.Gln310Gly | missense_variant | 0.44 | isoniazid | |
| dnaA | 933 | c.933C>G | synonymous_variant | 0.44 | isoniazid | |
| dnaA | 942 | c.942C>G | synonymous_variant | 0.54 | isoniazid | |
| dnaA | 945 | c.945G>A | synonymous_variant | 0.54 | isoniazid | |
| dnaA | 952 | c.952C>T | synonymous_variant | 0.46 | isoniazid | |
| dnaA | 955 | c.955_957delAGAinsCT | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 960 | c.960C>A | synonymous_variant | 0.55 | isoniazid | |
| dnaA | 963 | c.963C>G | synonymous_variant | 0.57 | isoniazid | |
| dnaA | 966 | c.966T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 969 | c.969G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 975 | c.975G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 984 | c.984T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 990 | c.990A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 993 | c.993A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 996 | c.996A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 999 | c.999C>G | synonymous_variant | 0.81 | isoniazid | |
| dnaA | 1003 | c.1003C>T | synonymous_variant | 0.83 | isoniazid | |
| dnaA | 1008 | c.1008G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1014 | c.1014C>G | synonymous_variant | 0.88 | isoniazid | |
| dnaA | 1024 | c.1024T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1038 | c.1038A>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1041 | c.1041G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1047 | c.1047A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1098 | c.1098A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1110 | c.1110T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1113 | c.1113A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1125 | c.1125G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1137 | c.1137C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1143 | c.1143G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1152 | c.1152A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1153 | c.1153T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1164 | c.1164A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1167 | c.1167A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1176 | c.1176A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1188 | c.1188G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1197 | c.1197T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1204 | c.1204C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1353 | c.1353T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1371 | c.1371T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1375 | c.1375T>C | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6238 | c.999G>A | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6242 | p.Arg335Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6256 | c.1017G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6259 | c.1020C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6265 | c.1026C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6268 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6289 | c.1050C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6346 | c.1107C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6361 | c.-941G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6376 | c.-926G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6379 | c.-923C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6403 | c.-899T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6415 | c.-887G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6418 | c.-884C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6427 | c.-875T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6469 | c.-833T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6475 | c.-827C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6484 | c.-818A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6490 | c.-812T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6499 | c.-803A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6502 | c.-800T>C | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6508 | c.-794A>G | upstream_gene_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6523 | c.-779G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6526 | c.-776T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6535 | c.-767C>G | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6565 | c.-737G>C | upstream_gene_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6571 | c.-731T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6577 | c.1338T>C | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6598 | c.-704C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6619 | c.-683T>C | upstream_gene_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.67 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6646 | c.-656C>T | upstream_gene_variant | 0.35 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.64 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.52 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.59 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6727 | c.-575G>T | upstream_gene_variant | 0.59 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6739 | c.-563C>T | upstream_gene_variant | 0.65 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6754 | c.-548C>T | upstream_gene_variant | 0.7 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6763 | c.1524G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6772 | c.1533C>G | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6775 | c.1536G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6798 | p.Gly520Ala | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Uncertain significance | |||||
| gyrB | 6808 | c.1569C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6824 | c.1585C>T | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.43 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.43 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6869 | c.-433T>C | upstream_gene_variant | 0.5 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6872 | c.1633_1635delTTGinsCT | frameshift_variant&synonymous_variant | 0.5 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.79 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.77 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 0.74 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7081 | c.-221T>C | upstream_gene_variant | 0.51 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.39 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7100 | c.1861T>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.35 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 0.61 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7124 | c.1885_1887delTCGinsAC | frameshift_variant&missense_variant | 0.39 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7135 | c.-167G>A | upstream_gene_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>A | upstream_gene_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7153 | c.1914G>C | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7168 | c.-134C>G | upstream_gene_variant | 0.66 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7186 | c.1947C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7189 | c.-113C>T | upstream_gene_variant | 0.71 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7198 | c.1959C>T | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 7210 | p.Asp657Glu | missense_variant | 0.64 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7213 | c.-89G>A | upstream_gene_variant | 0.6 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7216 | c.1977G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7225 | c.-77T>C | upstream_gene_variant | 0.71 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7234 | c.-68C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7334 | c.33G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7335 | p.Leu12Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7347 | c.46_48delGAAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7361 | c.60C>T | synonymous_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7406 | c.105G>C | synonymous_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 0.81 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7562 | c.261C>T | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 0.58 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7625 | c.324G>C | synonymous_variant | 0.61 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7673 | c.372G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382_384delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7710 | c.409_411delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7721 | c.420G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7725 | c.424C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7739 | c.438C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 0.66 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>C | synonymous_variant | 0.65 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7811 | c.510C>T | synonymous_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7823 | c.522G>C | synonymous_variant | 0.54 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7841 | c.540C>T | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7847 | c.546G>C | synonymous_variant | 0.5 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7853 | c.552C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7868 | p.Ile189Met | missense_variant | 0.57 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 7886 | c.585T>C | synonymous_variant | 0.38 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8189 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8234 | c.933T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8237 | c.936A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8247 | c.946_948delATCinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 0.89 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8270 | c.969G>T | synonymous_variant | 0.89 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8276 | c.975G>A | synonymous_variant | 0.89 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8330 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8337 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8342 | c.1041G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8357 | c.1056G>A | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8366 | c.1065G>T | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8367 | c.1066C>T | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8372 | c.1071G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8400 | c.1099_1101delGACinsAT | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8411 | c.1110C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8423 | c.1122G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8442 | c.1141C>T | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8465 | c.1164C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8472 | c.1171C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8528 | c.1227G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8531 | c.1230G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8543 | c.1242C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8553 | c.1252C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 0.76 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 0.68 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8696 | c.1395G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8708 | c.1407G>C | synonymous_variant | 0.67 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8731 | p.Gly477Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8740 | p.Arg480His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8750 | c.1449C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8751 | p.Ala484Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8780 | p.Asp493Glu | missense_variant | 0.7 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8783 | c.1482G>C | synonymous_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8792 | c.1491G>C | synonymous_variant | 0.44 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8799 | c.1498_1500delGCGinsTC | frameshift_variant&missense_variant | 0.47 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8807 | c.1506C>T | synonymous_variant | 0.49 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8816 | c.1515C>G | synonymous_variant | 0.52 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8817 | p.Ser506Asp | missense_variant | 0.48 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528_1530delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8837 | c.1536C>G | synonymous_variant | 0.51 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8846 | c.1545C>T | synonymous_variant | 0.52 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8891 | c.1590G>A | synonymous_variant | 0.47 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8933 | c.1632G>C | synonymous_variant | 0.46 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>T | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8945 | c.1644G>C | synonymous_variant | 0.53 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8957 | c.1656C>T | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8967 | p.Ala556Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8978 | c.1677C>T | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>A | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 0.58 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8993 | c.1692C>T | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9017 | c.1716C>G | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9018 | p.Gln573Lys | missense_variant | 0.6 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9026 | c.1725G>C | synonymous_variant | 0.58 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 0.39 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9035 | c.1734G>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9044 | c.1743C>G | synonymous_variant | 0.56 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9047 | c.1746C>T | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 0.43 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 0.47 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9063 | c.1762_1764delTCCinsGG | frameshift_variant&missense_variant | 0.48 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>G | synonymous_variant | 0.86 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9122 | c.1821C>A | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9153 | p.Thr618Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9158 | c.1857C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9161 | c.1860C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9191 | c.1890G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9218 | c.1917C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9224 | c.1923C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9239 | c.1938C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.97 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 0.81 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9291 | c.1990C>T | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9299 | c.1998G>C | synonymous_variant | 0.79 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9312 | c.2011C>T | synonymous_variant | 0.79 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 0.79 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 0.79 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9344 | c.2043C>T | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9359 | c.2058C>T | synonymous_variant | 0.67 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9365 | c.2064G>A | synonymous_variant | 0.67 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| fgd1 | 490812 | c.30A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490815 | c.33G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490827 | c.45C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490848 | c.66A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 490851 | c.69A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490868 | p.Ala29Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490887 | c.105G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490890 | c.108C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490896 | c.114C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490911 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490917 | c.135C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490929 | c.147C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490932 | c.150T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490935 | c.153C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490962 | c.180T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490974 | c.192T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490977 | c.195C>G | synonymous_variant | 0.91 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490980 | p.Asn66Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490987 | p.Leu69Thr | missense_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490998 | c.216T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491001 | c.219G>C | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 0.89 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.71 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491077 | p.Asn99Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491082 | c.300T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491091 | c.309T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491094 | c.312C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491097 | c.315G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491100 | c.318C>T | synonymous_variant | 0.61 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 0.62 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491115 | c.333G>C | synonymous_variant | 0.36 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491130 | c.348C>G | synonymous_variant | 0.65 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491144 | p.Ala121Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491151 | c.369G>A | synonymous_variant | 0.67 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491166 | c.384G>T | synonymous_variant | 0.39 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491173 | c.391C>A | synonymous_variant | 0.69 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 0.71 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491184 | c.402A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.76 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 0.76 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491289 | c.507C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491292 | c.510G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491302 | p.Ile174Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491307 | c.525C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491313 | c.531C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491319 | c.537G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491325 | c.543G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491337 | c.555C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491340 | c.558C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491553 | c.771G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491643 | c.861G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491646 | c.864G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491649 | c.867C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491661 | c.879C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491673 | c.891A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491676 | c.894T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491679 | c.897A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575042 | c.-306T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575052 | c.-296G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575057 | c.-291G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575060 | c.-288G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575075 | c.-273T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 575084 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575662 | c.315C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575674 | c.327G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575689 | c.342G>A | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575701 | c.354G>A | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| mshA | 575704 | c.357T>G | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 0.8 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| mshA | 575752 | c.405G>C | synonymous_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| mshA | 575755 | c.408G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 0.84 | ethionamide | |
| isoniazid | ||||||
| mshA | 575770 | c.423G>A | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575812 | c.465C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 575830 | c.483C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575890 | c.543C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575917 | p.Asp190Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575920 | c.573C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575924 | p.Gly193Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575950 | c.603C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575959 | c.612G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619507 | c.-384A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619528 | c.-363C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619531 | c.-360T>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619543 | c.-348C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619552 | c.-339A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619555 | c.-336C>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619561 | c.-330G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619570 | c.-321G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619574 | c.-317G>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619579 | c.-312G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619584 | c.-307A>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619591 | c.-300G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619594 | c.-297G>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619609 | c.-282G>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619634 | c.-257T>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619645 | c.-246G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619654 | c.-237A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620208 | c.318G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620226 | c.336G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620264 | p.Gly125Ala | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620268 | c.378G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | c.394_396delGCGinsCC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620295 | c.405G>T | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620310 | c.420C>T | synonymous_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620346 | c.456C>A | synonymous_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 0.82 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 0.81 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620376 | c.486G>C | synonymous_variant | 0.81 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 0.8 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620389 | c.499C>T | synonymous_variant | 0.8 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620424 | c.534G>C | synonymous_variant | 0.8 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620433 | c.543C>G | synonymous_variant | 0.79 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620436 | c.546T>A | synonymous_variant | 0.76 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620439 | c.549T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620460 | c.570T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620461 | p.Val191Ile | missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620481 | c.591T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620482 | p.Val198Leu | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620569 | c.679_681delGGAinsCC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620583 | c.693G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620586 | c.696C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620598 | c.708C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620601 | c.711C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620607 | c.717T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620613 | c.723C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620619 | c.729G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620622 | c.732G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620631 | c.741T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620659 | c.769_771delCGCinsAG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620664 | c.774C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620682 | c.792G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620688 | c.798G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620710 | c.820_822delGTGinsAA | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620742 | c.852G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620745 | c.855G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620763 | c.873G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620784 | c.894C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620787 | c.897C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620796 | c.906C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620823 | c.933C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| Rv0565c | 656289 | c.1182C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656298 | c.1173G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656304 | c.1167T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656325 | c.1146C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656383 | p.Val363Asn | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656391 | c.1080C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656402 | p.Ala357Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656412 | c.1059T>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656418 | c.1053A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656423 | c.1048T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657138 | c.331_333delGCAinsTG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657144 | c.327T>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657155 | p.Asn106Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657160 | p.Glu104Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657171 | c.300T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657231 | c.238_240delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657237 | c.234A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657261 | c.210C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657264 | c.207T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657267 | c.204G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657300 | c.171C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657318 | c.153T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657324 | c.147C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657327 | c.144C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657337 | p.Arg45Gln | missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657342 | c.129T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657347 | c.124A>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657348 | c.123A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657356 | p.Ile39Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657683 | c.-213C>G | upstream_gene_variant | 0.73 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.75 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731717 | c.-213T>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731732 | c.-198G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731792 | c.-138G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731801 | c.-129C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731816 | c.-114G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731840 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731843 | c.-87T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731849 | c.-81C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731852 | c.-78A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 732295 | c.366G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732305 | p.Ile126Val | missense_variant | 1.0 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732329 | p.Leu134Val | missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732337 | c.408G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 0.94 | isoniazid | |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 0.62 | rifampicin | |
| nusG | 734445 | c.192C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| nusG | 734451 | c.198G>C | synonymous_variant | 0.61 | rifampicin | |
| nusG | 734452 | p.Glu67Gln | missense_variant | 0.37 | rifampicin | Uncertain significance |
| nusG | 734457 | c.204C>G | synonymous_variant | 0.62 | rifampicin | |
| nusG | 734460 | c.207G>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734497 | c.244_246delGTGinsAC | frameshift_variant&missense_variant | 0.36 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734556 | c.303C>T | synonymous_variant | 0.73 | rifampicin | |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734601 | c.348C>G | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734610 | c.357C>G | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734625 | c.372T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734631 | c.378G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734634 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734637 | c.384G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734643 | c.390G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734652 | c.399T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734658 | c.405A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| nusG | 734661 | c.408A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734664 | c.411T>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734673 | c.420A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734676 | c.423G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734679 | c.426C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734680 | c.427_429delGCCinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734703 | c.450T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734709 | c.456T>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734715 | c.462G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734718 | c.465G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734719 | p.Ser156Ala | missense_variant | 1.0 | rifampicin | |
| nusG | 734726 | p.Arg158Lys | missense_variant | 1.0 | rifampicin | |
| nusG | 734733 | c.480T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734742 | c.489T>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734781 | c.528A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734784 | c.531G>A | synonymous_variant | 0.58 | rifampicin | |
| nusG | 734787 | c.534T>C | synonymous_variant | 0.58 | rifampicin | |
| nusG | 734792 | p.Val180Ala | missense_variant | 0.64 | rifampicin | |
| nusG | 734794 | p.Val181Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734814 | c.561G>C | synonymous_variant | 0.67 | rifampicin | |
| nusG | 734826 | c.573A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734829 | c.576C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
| nusG | 734841 | c.588G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734850 | c.597C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734882 | p.Ala210Gly | missense_variant | 0.53 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734913 | c.660C>G | synonymous_variant | 0.53 | rifampicin | |
| nusG | 734928 | c.675A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760079 | c.273G>A | synonymous_variant | 0.67 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760110 | c.304_306delTCTinsAGC | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.4 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 0.55 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760256 | c.450C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoB | 760274 | p.Glu156Asp | missense_variant | 0.34 | rifampicin | Uncertain significance |
| rpoB | 760276 | p.Lys157Met | missense_variant | 0.33 | rifampicin | Uncertain significance |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.83 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 0.47 | rifampicin | |
| rpoB | 760388 | c.582C>T | synonymous_variant | 0.51 | rifampicin | |
| rpoB | 760400 | c.594G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 0.55 | rifampicin | Uncertain significance |
| rpoB | 760412 | c.606C>G | synonymous_variant | 0.39 | rifampicin | |
| rpoB | 760415 | c.609C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 760418 | c.612G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760460 | c.654G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760502 | c.696C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 0.36 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoB | 760561 | c.757_758delCG | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 760565 | c.759A>G | synonymous_variant | 0.42 | rifampicin | |
| rpoB | 760567 | p.Ser254Trp | missense_variant | 0.56 | rifampicin | |
| rpoB | 760568 | c.762_763insGC | frameshift_variant | 0.56 | rifampicin | |
| rpoB | 760571 | c.765G>C | synonymous_variant | 0.56 | rifampicin | |
| rpoB | 760588 | p.Thr261Ile | missense_variant | 0.42 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760595 | c.789C>T | synonymous_variant | 0.42 | rifampicin | |
| rpoB | 760596 | p.Thr264Pro | missense_variant | 0.42 | rifampicin | |
| rpoB | 760608 | c.802C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760634 | c.828T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760703 | c.897C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoB | 760715 | c.909C>G | synonymous_variant | 0.64 | rifampicin | |
| rpoB | 760718 | c.912C>T | synonymous_variant | 0.63 | rifampicin | |
| rpoB | 760724 | c.918T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760751 | c.945G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760757 | c.951T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760759 | p.Val318Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760858 | p.Val351Ala | missense_variant | 0.87 | rifampicin | Uncertain significance |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760865 | c.1059C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoB | 760886 | p.Glu360Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760887 | p.Thr361Val | missense_variant | 0.73 | rifampicin | Uncertain significance |
| rpoB | 760910 | c.1104C>T | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
| rpoB | 760916 | c.1110C>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 0.39 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 0.47 | rifampicin | |
| rpoB | 760943 | c.1137C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760949 | c.1143C>T | synonymous_variant | 0.48 | rifampicin | |
| rpoB | 760965 | p.Met387Leu | missense_variant | 0.44 | rifampicin | Uncertain significance |
| rpoB | 760970 | c.1164G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoB | 760973 | c.1167G>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760997 | c.1191G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 761006 | c.1200C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 0.66 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761084 | c.1278C>A | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.39 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761129 | c.1323G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761147 | c.1341C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 761153 | c.1347G>C | synonymous_variant | 0.54 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761171 | c.1365C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 761178 | c.1372_1374delTCAinsAC | frameshift_variant&missense_variant | 0.46 | rifampicin | |
| rpoB | 761186 | p.Glu460Asp | missense_variant | 0.45 | rifampicin | Uncertain significance |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 0.56 | rifampicin | |
| rpoB | 761213 | c.1407G>C | synonymous_variant | 0.56 | rifampicin | |
| rpoB | 761219 | c.1413G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761273 | c.1467T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 761306 | c.1500C>G | synonymous_variant | 0.79 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 0.83 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 0.86 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761438 | c.1632G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761439 | c.1633_1635delGACinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761447 | c.1641C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761452 | p.Val549Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761457 | p.Pro551Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761477 | c.1671C>G | synonymous_variant | 0.89 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 0.89 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761528 | c.1722C>T | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761588 | c.1782C>T | synonymous_variant | 0.55 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.56 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761639 | c.1833G>A | synonymous_variant | 0.52 | rifampicin | |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 0.48 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 761657 | c.1851C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 0.45 | rifampicin | |
| rpoB | 761669 | c.1863C>T | synonymous_variant | 0.43 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761687 | c.1881C>T | synonymous_variant | 0.36 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoB | 761693 | c.1887G>C | synonymous_variant | 0.39 | rifampicin | |
| rpoB | 761705 | c.1899C>A | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoB | 761720 | c.1914_1919delCGAAGAinsGGAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 0.74 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 0.73 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761815 | p.Ala670Glu | missense_variant | 0.91 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 0.79 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 0.73 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 0.67 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 0.64 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761933 | c.2127G>C | synonymous_variant | 0.4 | rifampicin | |
| rpoB | 761936 | c.2130C>T | synonymous_variant | 0.41 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>A | synonymous_variant | 0.48 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoB | 761955 | p.Ile717Val | missense_variant | 0.5 | rifampicin | Uncertain significance |
| rpoB | 761969 | c.2163G>A | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoB | 761990 | c.2184G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 0.45 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 762038 | c.2232C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
| rpoB | 762047 | c.2241G>A | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762056 | c.2250G>A | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 0.52 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762134 | c.2328C>A | synonymous_variant | 0.5 | rifampicin | |
| rpoB | 762137 | c.2331C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762149 | c.2343G>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762194 | c.2388G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoB | 762206 | c.2400C>G | synonymous_variant | 0.45 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762236 | c.2430G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 762245 | c.2439G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 762246 | c.2440C>T | synonymous_variant | 0.56 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 0.59 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 0.62 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 0.64 | rifampicin | |
| rpoB | 762275 | c.2469C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762296 | c.2490G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762323 | c.2517C>A | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762341 | c.2535G>C | synonymous_variant | 0.34 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762353 | c.2547C>T | synonymous_variant | 0.33 | rifampicin | |
| rpoB | 762356 | p.Glu850Asp | missense_variant | 0.33 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762368 | p.Glu854Asp | missense_variant | 0.37 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762374 | c.-996G>T | upstream_gene_variant | 0.37 | rifampicin | |
| rpoC | 762380 | c.-990T>C | upstream_gene_variant | 0.37 | rifampicin | |
| rpoC | 762383 | c.-987C>G | upstream_gene_variant | 0.36 | rifampicin | |
| rpoC | 762386 | c.-984C>T | upstream_gene_variant | 0.36 | rifampicin | |
| rpoC | 762392 | c.-978G>C | upstream_gene_variant | 0.39 | rifampicin | |
| rpoC | 762395 | c.-975G>T | upstream_gene_variant | 0.39 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.54 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.55 | rifampicin | |
| rpoB | 762410 | c.2604T>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.55 | rifampicin | |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.54 | rifampicin | |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.67 | rifampicin | |
| rpoB | 762488 | c.2682G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762489 | p.Val895Gln | missense_variant | 0.58 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.97 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.97 | rifampicin | |
| rpoB | 762515 | c.2709C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.58 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762788 | c.2982G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762810 | c.3004_3006delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762866 | c.3060C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 762879 | p.Met1025Leu | missense_variant | 0.46 | rifampicin | Uncertain significance |
| rpoB | 762894 | c.3088C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 762899 | c.3093G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 762917 | c.3111C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoB | 762920 | c.3114C>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoB | 762923 | c.3117C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762959 | c.3153G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.41 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.43 | rifampicin | |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763082 | c.3276C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoB | 763088 | c.3282C>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763145 | c.3339G>A | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.49 | rifampicin | |
| rpoB | 763157 | c.3351G>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.5 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763172 | c.3366G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.61 | rifampicin | |
| rpoB | 763193 | c.3387C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763205 | c.-165G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.71 | rifampicin | |
| rpoB | 763214 | c.3408T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763227 | c.3421C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763259 | c.-111G>C | upstream_gene_variant | 0.38 | rifampicin | |
| rpoC | 763262 | c.-108C>T | upstream_gene_variant | 0.38 | rifampicin | |
| rpoC | 763265 | c.-105G>C | upstream_gene_variant | 0.38 | rifampicin | |
| rpoB | 763268 | c.3462C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763283 | c.3477T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763365 | c.-5_-4insT | upstream_gene_variant | 0.67 | rifampicin | Uncertain significance |
| rpoC | 763402 | c.33C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763415 | c.46_48delACCinsTG | frameshift_variant&missense_variant | 0.46 | rifampicin | |
| rpoC | 763423 | p.Glu18Asp | missense_variant | 0.39 | rifampicin | Uncertain significance |
| rpoC | 763430 | c.61_63delAGGinsCA | frameshift_variant&missense_variant | 0.38 | rifampicin | |
| rpoC | 763433 | c.64_66delCAAinsAC | frameshift_variant&missense_variant | 0.38 | rifampicin | |
| rpoC | 763441 | c.72C>T | synonymous_variant | 0.6 | rifampicin | |
| rpoC | 763443 | p.Tyr25Phe | missense_variant | 0.4 | rifampicin | |
| rpoC | 763450 | c.81G>A | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 0.52 | rifampicin | |
| rpoC | 763492 | c.123G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763531 | c.162G>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoC | 763633 | c.264T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 763657 | c.288G>A | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763699 | c.330G>T | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>C | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 763711 | c.342G>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763732 | c.363C>A | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763747 | c.378G>A | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763781 | p.Ser138Ala | missense_variant | 0.37 | rifampicin | |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 0.37 | rifampicin | |
| rpoC | 763796 | c.427_429delATGinsCC | frameshift_variant&missense_variant | 0.4 | rifampicin | |
| rpoC | 763801 | c.432C>T | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763831 | c.462A>G | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 763835 | p.Ala156Lys | missense_variant | 0.47 | rifampicin | |
| rpoC | 763840 | c.471G>C | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 763844 | p.Arg159Lys | missense_variant | 0.5 | rifampicin | |
| rpoC | 763853 | p.Val162Ile | missense_variant | 0.47 | rifampicin | |
| rpoC | 763857 | p.Glu163Ala | missense_variant | 0.53 | rifampicin | |
| rpoC | 763861 | c.492C>T | synonymous_variant | 0.56 | rifampicin | |
| rpoC | 763870 | c.501C>T | synonymous_variant | 0.6 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763933 | c.564C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoC | 763936 | c.567C>G | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 763940 | c.571_573delGCCinsTG | frameshift_variant&missense_variant | 0.61 | rifampicin | |
| rpoC | 763945 | c.576T>C | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 763947 | p.Ala193Val | missense_variant | 0.58 | rifampicin | Uncertain significance |
| rpoC | 763949 | c.580_582delCGGinsAC | frameshift_variant&missense_variant | 0.45 | rifampicin | |
| rpoC | 763954 | c.585C>G | synonymous_variant | 0.49 | rifampicin | |
| rpoC | 763960 | c.591T>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 763963 | c.594C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 763969 | c.600C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoC | 763987 | c.618C>T | synonymous_variant | 0.48 | rifampicin | |
| rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763999 | c.630C>T | synonymous_variant | 0.48 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764003 | c.634_636delGCGinsTC | frameshift_variant&missense_variant | 0.48 | rifampicin | |
| rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764029 | p.Glu220Asp | missense_variant | 0.44 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764054 | c.685C>T | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoC | 764110 | c.741C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.64 | rifampicin | |
| rpoC | 764116 | c.747C>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 0.59 | rifampicin | |
| rpoC | 764140 | c.771C>T | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
| rpoC | 764143 | c.774G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoC | 764147 | c.778_780delTCGinsGC | frameshift_variant&missense_variant | 0.36 | rifampicin | |
| rpoC | 764150 | c.781_783delATCinsGG | frameshift_variant&missense_variant | 0.36 | rifampicin | |
| rpoC | 764165 | p.Glu266Gln | missense_variant | 0.38 | rifampicin | |
| rpoC | 764176 | c.807C>T | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 764182 | c.813C>T | synonymous_variant | 0.34 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764207 | p.Val280Ile | missense_variant | 0.33 | rifampicin | |
| rpoC | 764215 | c.846A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764236 | c.867G>A | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
| rpoC | 764242 | c.873C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 764248 | c.879C>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
| rpoC | 764254 | c.885G>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.66 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 0.72 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 0.83 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764353 | c.984G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764387 | c.1018T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 0.71 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764470 | c.1101C>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764524 | c.1155C>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
| rpoC | 764530 | c.1161C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
| rpoC | 764534 | c.1165C>A | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764542 | c.1173C>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
| rpoC | 764545 | c.1176C>A | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoC | 764692 | c.1323C>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoC | 764713 | c.1344G>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764810 | p.Pro481Ala | missense_variant | 0.5 | rifampicin | Uncertain significance |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 764875 | c.1506C>A | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 0.47 | rifampicin | Uncertain significance |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 0.51 | rifampicin | |
| rpoC | 764948 | c.1579_1581delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R |
| rpoC | 765011 | p.Ser548Cys | missense_variant | 0.34 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 0.62 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765053 | p.Ser562Arg | missense_variant | 0.57 | rifampicin | |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765085 | c.1716T>C | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765100 | c.1731G>C | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765121 | c.1752G>T | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 765292 | c.1923G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765298 | c.1929G>C | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765305 | p.Ile646Val | missense_variant | 0.5 | rifampicin | Uncertain significance |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765328 | p.His653Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765329 | p.Ser654Asp | missense_variant | 0.48 | rifampicin | |
| rpoC | 765334 | c.1965C>T | synonymous_variant | 0.52 | rifampicin | |
| rpoC | 765343 | c.1974G>A | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 0.53 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765356 | c.1987_1989delATGinsGC | frameshift_variant&missense_variant | 0.46 | rifampicin | |
| rpoC | 765370 | c.2001G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoC | 765379 | c.2010G>C | synonymous_variant | 0.57 | rifampicin | |
| rpoC | 765382 | c.2013G>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765403 | c.2034G>C | synonymous_variant | 0.55 | rifampicin | |
| rpoC | 765404 | p.Leu679Asp | missense_variant | 0.45 | rifampicin | |
| rpoC | 765409 | c.2040T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765449 | c.2080_2082delGCCinsTG | frameshift_variant&missense_variant | 0.46 | rifampicin | |
| rpoC | 765454 | c.2085C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 765469 | c.2100G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765480 | p.Tyr704Phe | missense_variant | 0.34 | rifampicin | Uncertain significance |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 0.78 | rifampicin | |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 0.83 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765559 | c.2190G>C | synonymous_variant | 0.84 | rifampicin | |
| rpoC | 765580 | c.2211G>C | synonymous_variant | 0.83 | rifampicin | |
| rpoC | 765613 | p.His748Gln | missense_variant | 0.92 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoC | 765875 | p.Val836Ile | missense_variant | 0.31 | rifampicin | Uncertain significance |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 0.68 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
| rpoC | 765907 | c.2538G>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
| rpoC | 765940 | c.2571A>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoC | 765964 | p.Leu865Phe | missense_variant | 0.31 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.81 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766030 | c.2661C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 766036 | c.2667C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766054 | c.2685C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766082 | p.Ala905Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766096 | c.2727G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766135 | c.2766G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766142 | c.2773C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766168 | c.2799C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766174 | p.Asn935Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766178 | p.Ile937Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 766185 | p.Glu939Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766189 | c.2820T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766258 | c.2889T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766273 | c.2904T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766274 | p.Ala969Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766280 | p.Ser971Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766288 | c.2919C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766303 | c.2934C>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 766312 | c.2943T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766327 | c.2958C>A | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766357 | c.2988C>T | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766462 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766507 | c.3138C>T | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 766513 | c.3144C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 0.64 | rifampicin | |
| rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.64 | rifampicin | |
| rpoC | 766588 | c.3219G>A | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 0.64 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766673 | p.Gly1102Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 766858 | c.3489C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 0.65 | rifampicin | |
| rpoC | 766867 | c.3498C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 766885 | c.3516G>A | synonymous_variant | 0.34 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766911 | p.Ile1181Thr | missense_variant | 0.35 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 0.37 | rifampicin | |
| rpoC | 766931 | c.3562_3564delGCAinsTG | frameshift_variant&stop_gained | 0.41 | rifampicin | |
| rpoC | 766942 | c.3573C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 766945 | c.3576A>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 0.56 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 767008 | c.3639G>A | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 767014 | c.3645G>C | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 767023 | c.3654C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.48 | rifampicin | |
| rpoC | 767044 | c.3675G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 767080 | c.3711G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 767107 | c.3738C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767125 | c.3756G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 767134 | c.3765C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoC | 767138 | c.3769C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 767149 | c.3780C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767179 | c.3810C>T | synonymous_variant | 0.55 | rifampicin | |
| rpoC | 767180 | p.Ala1271* | stop_gained | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767197 | c.3828G>A | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
| rpoC | 767203 | c.3834C>G | synonymous_variant | 0.57 | rifampicin | |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767254 | c.3885G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
| rpoC | 767264 | p.Ala1299Tyr | missense_variant | 1.0 | rifampicin | |
| rpoC | 767267 | p.Ala1300Asn | missense_variant | 0.71 | rifampicin | Uncertain significance |
| rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767284 | c.3915C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpsL | 781571 | c.12C>T | synonymous_variant | 0.44 | streptomycin | |
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 0.43 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 0.67 | streptomycin | |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781700 | c.141G>C | synonymous_variant | 0.68 | streptomycin | |
| rpsL | 781703 | c.144G>T | synonymous_variant | 0.7 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 0.77 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781772 | c.213C>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781802 | c.243G>C | synonymous_variant | 0.44 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.54 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.55 | streptomycin | |
| rpsL | 781814 | c.255C>T | synonymous_variant | 0.44 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 0.45 | streptomycin | |
| rpsL | 781829 | c.270G>C | synonymous_variant | 0.44 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 0.54 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 0.54 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 0.47 | streptomycin | Not assoc w R - Interim |
| rpsL | 781865 | c.306G>C | synonymous_variant | 0.52 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>A | synonymous_variant | 0.45 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 0.55 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 0.45 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 0.32 | streptomycin | |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.89 | linezolid | |
| rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.89 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.9 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.91 | linezolid | |
| rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800817 | c.9A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 0.87 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800874 | c.66A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800875 | c.67_69delGTAinsAT | frameshift_variant&missense_variant | 0.86 | linezolid | |
| rplC | 800880 | c.72A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 0.86 | linezolid | |
| rplC | 800892 | c.84G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 0.86 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 0.86 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800939 | p.Arg44Gln | missense_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800967 | c.159C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 0.81 | linezolid | Not assoc w R - Interim |
| rplC | 800982 | c.174C>T | synonymous_variant | 0.8 | linezolid | |
| rplC | 801195 | c.387G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801207 | c.399C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801246 | c.438C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801249 | c.441T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801267 | c.459A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801279 | c.471G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801282 | c.474G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801285 | c.477G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801300 | c.492C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801309 | c.501C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801321 | c.513C>T | synonymous_variant | 0.97 | linezolid | Not assoc w R - Interim |
| rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801339 | c.531T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801427 | p.Met207Val | missense_variant | 1.0 | linezolid | |
| rplC | 801438 | c.630T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801442 | p.Ile212Val | missense_variant | 1.0 | linezolid | |
| fbiC | 1303455 | c.525C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303464 | c.534A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303476 | c.546G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303480 | p.Gln184Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303489 | c.559C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303497 | c.567G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303501 | c.571C>T | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303521 | c.591C>T | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303530 | c.600G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303539 | c.609G>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303614 | c.684C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303681 | c.751T>C | synonymous_variant | 0.7 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303686 | c.756C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 0.8 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303728 | c.798G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303731 | c.801A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303732 | p.Ser268Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 0.79 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303749 | c.819G>C | synonymous_variant | 0.83 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303755 | c.825T>C | synonymous_variant | 0.83 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303761 | c.831T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303785 | c.855G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303797 | c.867A>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303836 | c.906G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303845 | c.915C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303846 | p.Phe306Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303860 | c.930A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303884 | c.954T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303905 | c.975G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303914 | c.984C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303920 | c.990C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303944 | c.1014G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303947 | c.1017T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303948 | p.Gly340Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303953 | p.Asp341Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303956 | c.1026A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303971 | c.1041T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303980 | c.1050G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304031 | c.1101C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304034 | c.1104A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304040 | c.1110C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304046 | c.1116C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304049 | c.1119T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304050 | c.1120T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304058 | c.1128G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304059 | c.1129C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304085 | c.1155C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304106 | c.1176G>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304127 | c.1197A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304132 | p.Ala401Gly | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304142 | c.1212G>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304161 | p.Arg411Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304169 | c.1239T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304174 | p.Val415Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304184 | c.1254G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304187 | c.1257T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304208 | c.1278C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304226 | c.1296C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304227 | p.Met433Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304232 | c.1302G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304526 | c.1596T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304535 | c.1605G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304544 | c.1614T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304545 | p.Val539Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304553 | c.1623C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304565 | c.1635C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304568 | c.1638T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.83 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304694 | c.1764A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.85 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304784 | c.1854T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304787 | c.1857T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304832 | c.1902C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304875 | p.Ile649Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304883 | p.Glu651Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304891 | p.Ile654Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304907 | c.1977C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304910 | c.1980G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304916 | c.1986T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304983 | c.2053C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304995 | p.Leu689Met | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305012 | c.2082G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305030 | c.2100G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305033 | c.2103T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305042 | c.2112A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305045 | c.2115A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305252 | c.2322G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305276 | c.2346G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305279 | p.His783Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305297 | c.2367G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305300 | c.2370A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305303 | c.2373T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305306 | c.2376A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305309 | c.2379G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305310 | p.Arg794Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305318 | c.2388C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305336 | c.2406T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305372 | c.2442G>A | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305384 | c.2454G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305396 | c.2466C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364650 | p.Thr80Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364670 | c.258G>A | synonymous_variant | 0.87 | pyrazinamide | |
| sigE | 1364676 | c.264C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364680 | p.Gln90Glu | missense_variant | 0.83 | pyrazinamide | |
| sigE | 1364685 | c.273C>T | synonymous_variant | 0.83 | pyrazinamide | |
| sigE | 1364691 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364694 | c.282G>C | synonymous_variant | 0.83 | pyrazinamide | |
| sigE | 1364703 | c.291G>C | synonymous_variant | 0.85 | pyrazinamide | |
| sigE | 1364709 | c.297T>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364712 | c.300T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364718 | c.306C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364726 | p.Asn105Ser | missense_variant | 0.85 | pyrazinamide | |
| sigE | 1364733 | p.His107Gln | missense_variant | 0.85 | pyrazinamide | |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364751 | c.339C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364757 | c.345G>A | synonymous_variant | 0.83 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364778 | c.366G>C | synonymous_variant | 0.75 | pyrazinamide | |
| sigE | 1364782 | c.370_372delGTCinsTG | frameshift_variant&missense_variant | 0.77 | pyrazinamide | Uncertain significance |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364799 | c.387G>C | synonymous_variant | 0.67 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427_429delTTGinsCC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| atpE | 1460840 | c.-205A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460852 | c.-193C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460855 | c.-190T>C | upstream_gene_variant | 0.91 | bedaquiline | |
| atpE | 1460858 | c.-187C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460861 | c.-184C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1461113 | c.69C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461146 | c.102G>T | synonymous_variant | 0.45 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461150 | c.106_108delATCinsGT | frameshift_variant&missense_variant | 0.55 | bedaquiline | |
| atpE | 1461158 | c.114T>G | synonymous_variant | 0.55 | bedaquiline | |
| atpE | 1461159 | c.115_117delGTCinsAG | frameshift_variant&missense_variant | 0.55 | bedaquiline | |
| atpE | 1461164 | c.120C>T | synonymous_variant | 0.45 | bedaquiline | |
| atpE | 1461167 | c.123G>T | synonymous_variant | 0.45 | bedaquiline | |
| atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461179 | c.135G>T | synonymous_variant | 0.43 | bedaquiline | |
| atpE | 1461182 | c.138A>G | synonymous_variant | 0.43 | bedaquiline | |
| atpE | 1461185 | c.141G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461233 | c.189A>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461251 | c.207G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461254 | c.210T>C | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.94 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.8 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.73 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472300 | n.455C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474964 | n.1307T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
| linezolid | ||||||
| rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
| linezolid | ||||||
| rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476105 | n.2448G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
| linezolid | ||||||
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476717 | n.3060C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
| linezolid | ||||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
| linezolid | ||||||
| rrl | 1476755 | n.3098G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673602 | c.-600C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673615 | p.Glu59Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673619 | c.-583T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673633 | p.Ser65Asn | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673637 | p.Asp66Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673641 | p.Val68Ile | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673646 | c.-556T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673657 | p.Thr73Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673660 | p.Ala74Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673679 | c.-523T>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1673685 | c.-517C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673710 | p.Leu91Ile | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673890 | p.Ala151Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673901 | c.-301A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673905 | p.Ser156Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673916 | c.-286A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673917 | p.Val160Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673941 | c.502_504delGCCinsTT | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673946 | c.-256C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673955 | c.-247G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673961 | c.-241A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673985 | c.-217C>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674006 | p.Asp189Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674018 | c.-184G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674021 | c.-181G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674024 | c.-178T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674033 | c.-169T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674037 | p.Gln200Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674049 | c.610_612delCAAinsGC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674054 | c.-148T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674060 | c.-142A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674063 | c.-139G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674079 | p.Pro214Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674672 | c.471C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674708 | c.507G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674723 | c.522C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674738 | c.537C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674741 | c.540C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674746 | p.Tyr182Phe | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674774 | c.573A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674789 | c.588G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674828 | c.627G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674846 | p.Ile215Met | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674855 | c.654C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674864 | c.663C>T | synonymous_variant | 0.86 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674909 | c.708G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674942 | c.741T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674960 | c.759C>G | synonymous_variant | 0.79 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674967 | p.Asp256Thr | missense_variant | 0.75 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674987 | c.786C>T | synonymous_variant | 0.7 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833536 | c.-6A>C | upstream_gene_variant | 0.62 | pyrazinamide | |
| rpsA | 1833540 | c.-2_-1delATinsC | upstream_gene_variant | 0.59 | pyrazinamide | |
| rpsA | 1833547 | c.6G>A | synonymous_variant | 0.52 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.59 | pyrazinamide | Uncertain significance |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 0.59 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833596 | p.Ser19Ala | missense_variant | 0.41 | pyrazinamide | |
| rpsA | 1833604 | c.63C>T | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1833616 | c.75A>T | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833625 | c.84A>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 0.51 | pyrazinamide | |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 0.5 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 0.48 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833685 | c.144G>C | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1833691 | c.150G>A | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833694 | c.153G>T | synonymous_variant | 0.48 | pyrazinamide | |
| rpsA | 1833697 | c.156C>T | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1833700 | c.159C>T | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1833709 | c.168C>T | synonymous_variant | 0.54 | pyrazinamide | |
| rpsA | 1833721 | c.180A>G | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1833724 | c.183C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833733 | c.192C>G | synonymous_variant | 0.5 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 0.52 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833823 | c.282G>A | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>T | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833886 | c.345C>G | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 0.48 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 0.55 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1833961 | c.420C>G | synonymous_variant | 0.48 | pyrazinamide | |
| rpsA | 1833970 | c.429G>T | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1833971 | c.430C>T | synonymous_variant | 0.52 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833991 | c.450C>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1834012 | c.471G>C | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834033 | c.492C>T | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834073 | p.Lys178Arg | missense_variant | 0.38 | pyrazinamide | |
| rpsA | 1834096 | c.555G>C | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 0.51 | pyrazinamide | |
| rpsA | 1834105 | c.564C>G | synonymous_variant | 0.51 | pyrazinamide | |
| rpsA | 1834108 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834114 | c.573G>C | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1834123 | c.582C>G | synonymous_variant | 0.76 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 0.68 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 0.67 | pyrazinamide | |
| rpsA | 1834210 | c.669C>T | synonymous_variant | 0.63 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 0.56 | pyrazinamide | |
| rpsA | 1834228 | c.687C>A | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834231 | c.690T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834234 | c.693G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834246 | c.705G>T | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1834252 | c.711C>G | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.52 | pyrazinamide | |
| rpsA | 1834279 | c.738C>T | synonymous_variant | 0.48 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834294 | c.753G>T | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 0.53 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834327 | c.786G>T | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1834333 | c.792C>T | synonymous_variant | 0.51 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834357 | c.816T>C | synonymous_variant | 0.51 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>C | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834414 | c.873C>T | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834420 | c.879C>T | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834429 | c.888C>T | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 0.55 | pyrazinamide | |
| rpsA | 1834438 | c.897C>T | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 0.48 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.55 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1834477 | c.936C>T | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834510 | c.969C>T | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 0.53 | pyrazinamide | |
| rpsA | 1834519 | c.978G>C | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1834520 | c.979_981delGCCinsTG | frameshift_variant&missense_variant | 0.41 | pyrazinamide | Uncertain significance |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834534 | c.993C>T | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 0.57 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834552 | c.1011G>T | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1834557 | p.Ala339Gly | missense_variant | 0.43 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>T | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAC | frameshift_variant&missense_variant | 0.37 | pyrazinamide | Uncertain significance |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.68 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 0.3 | pyrazinamide | |
| rpsA | 1834684 | c.1143C>T | synonymous_variant | 0.65 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834700 | p.Gln387Glu | missense_variant | 0.34 | pyrazinamide | |
| rpsA | 1834720 | c.1179C>G | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.65 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.72 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.69 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.66 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.8 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.8 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.78 | linezolid | |
| tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.84 | linezolid | |
| tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 0.94 | linezolid | |
| tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853481 | c.-125A>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853484 | c.-122_-120delAGCinsGCG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853495 | c.-111G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853498 | c.-108G>C | upstream_gene_variant | 1.0 | linezolid | |
| tlyA | 1918197 | c.258T>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918206 | c.267G>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918212 | c.273A>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918218 | c.279C>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918221 | c.282T>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918224 | c.285G>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918236 | c.297A>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918245 | c.306C>T | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| tlyA | 1918248 | c.309T>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918251 | c.312T>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918271 | p.Ala111Val | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918275 | c.336T>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918278 | c.339C>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918308 | c.369C>T | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918310 | p.Asn124Ser | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918323 | c.384G>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918326 | c.387G>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918330 | p.Leu131Val | missense_variant | 1.0 | capreomycin | |
| bacA | 2064972 | c.-244T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064978 | c.-250G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064979 | c.-251C>T | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064984 | c.-256A>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064993 | c.-265T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| ndh | 2101804 | c.1239T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101808 | p.Thr412Ser | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101830 | p.Ile405Val | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101837 | p.Ala402Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
| delamanid | ||||||
| isoniazid | Uncertain significance | |||||
| ndh | 2101872 | p.Ile391Phe | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101873 | c.1168_1170delTTTinsCG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2101885 | c.1158G>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101888 | c.1155T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101891 | c.1152C>G | synonymous_variant | 0.91 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101894 | c.1149T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101912 | c.1131G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101920 | c.1123A>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101924 | c.1119T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101939 | c.1104A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101951 | c.1092C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101960 | c.1083A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101963 | c.1080G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101966 | c.1077T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101972 | c.1071G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101988 | p.Ala352Asp | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101990 | c.1053G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101993 | c.1050A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102014 | c.1029C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102131 | c.910_912delCAAinsAG | frameshift_variant&synonymous_variant | 1.0 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102140 | c.903C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102155 | c.888G>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102158 | c.885T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102162 | p.Arg294Thr | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102164 | c.879A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102167 | c.876A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102170 | p.Glu291Asp | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102176 | c.867T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102182 | c.859_861delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102190 | c.853T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102192 | p.Arg284Pro | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102206 | c.837G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102212 | c.831G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102218 | c.825C>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102227 | c.816C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102230 | c.813G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102233 | c.810G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102302 | c.741G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102305 | c.738T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102314 | c.729C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102317 | c.726A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102401 | c.642T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102407 | c.636T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102413 | c.630G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| katG | 2155632 | c.480A>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155637 | p.Leu159Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155641 | p.Lys157Asn | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155661 | p.Val151Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155668 | c.444G>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155677 | c.435C>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155680 | c.432G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155695 | c.417C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155704 | c.408C>G | synonymous_variant | 0.95 | isoniazid | |
| katG | 2155716 | c.396T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 0.92 | isoniazid | |
| katG | 2155740 | p.Gly124Gln | missense_variant | 0.92 | isoniazid | |
| katG | 2155743 | c.369G>C | synonymous_variant | 1.0 | isoniazid | |
| pncA | 2290009 | c.-768A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290015 | c.-774A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290024 | c.-783C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290030 | c.-791_-789delAATinsCC | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290033 | c.-792C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290038 | c.-797G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290042 | c.-801T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| kasA | 2517917 | c.-198G>C | upstream_gene_variant | 0.54 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.61 | isoniazid | |
| kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.43 | isoniazid | |
| kasA | 2517953 | c.-162C>T | upstream_gene_variant | 0.56 | isoniazid | |
| kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.52 | isoniazid | |
| kasA | 2517968 | c.-147T>A | upstream_gene_variant | 0.52 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.49 | isoniazid | |
| kasA | 2517989 | c.-126T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517993 | c.-122G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518019 | c.-96A>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518025 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518459 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518462 | c.348A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518468 | c.354A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518474 | c.360G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518483 | c.369C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518540 | c.426T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518570 | c.456G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518573 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518579 | c.465T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518639 | c.525G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518657 | c.543G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 0.5 | isoniazid | |
| kasA | 2518768 | c.654C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518777 | c.663C>T | synonymous_variant | 0.6 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518822 | c.708C>A | synonymous_variant | 0.37 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518846 | c.732G>T | synonymous_variant | 0.35 | isoniazid | |
| kasA | 2518853 | p.Leu247Val | missense_variant | 0.35 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518879 | c.765A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518898 | c.784T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518910 | p.Leu266Met | missense_variant | 1.0 | isoniazid | |
| kasA | 2518921 | c.807T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518936 | c.822C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518939 | c.825T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518942 | c.828T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519050 | c.936C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519053 | c.939G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519056 | c.942G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519062 | c.948T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519068 | c.954C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519072 | p.Ala320Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2519095 | c.981C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519107 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519108 | c.994_996delGATinsCG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2519116 | c.1002C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519122 | c.1008G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519137 | c.1023T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519158 | c.1044C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519167 | c.1053T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519196 | p.Thr361Ser | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726303 | c.111T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726311 | p.Ser40Asn | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726315 | p.Asp41Glu | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726318 | p.Glu42Asp | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726322 | c.130_132delCCAinsGC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| ahpC | 2726330 | c.138G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726336 | c.144G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726348 | c.156T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726357 | c.165A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726528 | c.336C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726540 | c.348C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726543 | c.351A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726546 | c.354C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726551 | p.Gln120Leu | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726556 | c.364_366delGCAinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| ahpC | 2726561 | c.369T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726564 | c.372C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726579 | c.387T>C | synonymous_variant | 0.94 | isoniazid | |
| ahpC | 2726591 | c.399C>G | synonymous_variant | 0.94 | isoniazid | |
| ahpC | 2726593 | p.Val134Ala | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726600 | c.408T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726601 | p.Ile137Leu | missense_variant | 0.96 | isoniazid | |
| ahpC | 2726638 | p.Ala149Val | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726645 | c.453C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726651 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726657 | c.465A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726669 | p.Asp159Glu | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726672 | c.480G>A | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726675 | c.483A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726681 | c.489A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726687 | c.495C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726693 | c.501C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726696 | c.504C>G | synonymous_variant | 1.0 | isoniazid | |
| folC | 2746308 | p.Arg431Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746321 | c.1278A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746328 | p.Arg424Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746335 | p.Gly422Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746336 | c.1263C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746345 | c.1254G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747289 | p.Pro104Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747293 | c.306G>A | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| folC | 2747314 | c.285A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747317 | c.282C>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| folC | 2747335 | c.264G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747343 | p.Val86Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747355 | p.Val82Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747362 | c.237G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747394 | p.Ile69Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747395 | c.204T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| folC | 2747407 | c.192T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| Rv2477c | 2782393 | c.1650C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782396 | c.1647G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782399 | c.1644T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782408 | c.1635T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782411 | c.1632C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782414 | p.Asp543Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782418 | p.Val542Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Uncertain significance | |||||
| amikacin | ||||||
| Rv2477c | 2782420 | c.1623T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782423 | c.1620C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782432 | c.1609_1611delGTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2782441 | c.1602G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782450 | c.1593C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782453 | c.1590C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782513 | c.1530G>T | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782522 | c.1521G>C | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782841 | p.Thr401Asn | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782847 | p.Arg399Lys | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | ||||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782894 | c.1149C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782930 | c.1113G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.56 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783044 | c.999G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783047 | p.Asp332Gly | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783092 | c.951A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783095 | c.948C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783098 | c.945C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783101 | c.942G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783107 | c.936G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783116 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.72 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.74 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783182 | c.861C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783185 | c.858G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783194 | c.849A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783221 | c.822G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783224 | c.819C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783230 | c.813T>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783235 | c.808T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783254 | c.789A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783275 | c.768C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.83 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783302 | c.741A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.8 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783317 | c.726G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.76 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.75 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.72 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.71 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783485 | c.558G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783491 | c.552C>T | synonymous_variant | 0.5 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783509 | c.534C>A | synonymous_variant | 0.5 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783515 | c.528C>G | synonymous_variant | 0.44 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783523 | c.520C>T | synonymous_variant | 0.49 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.55 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.55 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.59 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783563 | c.480A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783568 | p.Asn159His | missense_variant | 0.35 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.69 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783620 | c.423C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783650 | c.393C>T | synonymous_variant | 0.89 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783776 | c.267G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783883 | c.160T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783884 | c.159T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.88 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783953 | c.90G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| ribD | 2987042 | c.204A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| ribD | 2987046 | p.Val70Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| ribD | 2987058 | c.220T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| ribD | 2987066 | c.228A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| ribD | 2987069 | c.231T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| ribD | 2987092 | p.Val85Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| Rv2752c | 3064860 | c.1332G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064863 | c.1329G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064896 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064914 | c.1278T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064956 | c.1234_1236delAGTinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3064962 | c.1230C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064973 | p.Ala407Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064995 | c.1197C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064998 | c.1194A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065007 | c.1185G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065018 | p.Asn392His | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065022 | c.1170G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065028 | c.1162_1164delGTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065040 | c.1152C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065048 | c.1144C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065052 | c.1140G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065055 | c.1137T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065079 | c.1113T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065082 | c.1110G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065085 | c.1105_1107delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065109 | c.1081_1083delAGAinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065115 | c.1077C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065126 | p.Ser356Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065127 | c.1065G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065131 | p.Ala354Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065151 | c.1041G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065553 | c.639A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065562 | c.630T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065569 | p.Ile208His | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065580 | c.612G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065586 | c.606C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065595 | p.Leu199Phe | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065598 | c.594G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065607 | c.585C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065612 | p.Thr194Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065616 | c.576C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065622 | c.570G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065625 | c.567G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065634 | c.558G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065637 | c.555A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065640 | c.552T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065646 | c.546C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065649 | c.543T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065659 | p.Pro178Leu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065661 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065664 | c.526_528delTTGinsCT | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065667 | c.525A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065675 | p.Phe173Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065955 | c.235_237delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065979 | c.213T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065993 | p.Val67Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065994 | c.198T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066002 | p.Met64Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066009 | c.183G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066018 | c.174T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066024 | c.168T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066040 | p.Gly51Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066042 | c.150T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066045 | c.147T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066050 | p.Leu48Met | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066054 | c.138T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066066 | c.126T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066075 | c.117A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066102 | c.90C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066118 | p.Asn25Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066150 | c.42C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066309 | c.-118T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066315 | c.-124C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066330 | c.-139G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066335 | c.-144T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066339 | c.-148G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066360 | c.-169T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066369 | c.-180_-178delAGCinsGCG | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066380 | c.-189A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066432 | c.-241T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066435 | c.-246_-244delGGTinsAAC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066452 | c.-261T>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066453 | c.-262G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066456 | c.-265A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066462 | c.-271G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066465 | c.-276_-274delGGGinsAAT | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066471 | c.-280A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066476 | c.-285C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066482 | c.-291G>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066483 | c.-292T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066522 | c.-331C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066561 | c.-370A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066567 | c.-376C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066618 | c.-427A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066696 | c.-505T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066704 | c.-513C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066707 | c.-516A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066713 | c.-522C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066714 | c.-523G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066734 | c.-543G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066744 | c.-553C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066747 | c.-558_-556delCAAinsATC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066756 | c.-567_-565delCGGinsAC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066762 | c.-571G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066771 | c.-580C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066774 | c.-583T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066780 | c.-589C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066807 | c.-616T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066810 | c.-619G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066819 | c.-628T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066822 | c.-631T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066834 | c.-643G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066839 | c.-648A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066960 | c.-769C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066969 | c.-778G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066981 | c.-790T>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066987 | c.-796C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067274 | c.672C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067277 | c.669C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067281 | p.Val222Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067284 | p.Ala221Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067286 | c.660C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067289 | c.657C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067292 | c.654G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067295 | c.651C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067316 | c.630A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067325 | c.621A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067349 | c.597G>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067367 | c.579G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067379 | c.567C>T | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067389 | p.Thr186Ser | missense_variant | 0.94 | para-aminosalicylic_acid | |
| thyX | 3067391 | c.555G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067445 | c.501C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.489C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067465 | p.Ile161Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067470 | p.Asn159Ser | missense_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067472 | c.474C>G | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067475 | c.471A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067481 | c.465C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067490 | c.456C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067493 | c.453A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067515 | p.Ser144Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067530 | p.Ala139Ser | missense_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067545 | p.Glu134Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067549 | p.Thr133Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067556 | p.His130Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067559 | c.387C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067565 | p.Asp127Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067570 | p.Ala126Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067577 | c.369G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067601 | p.Arg115His | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067611 | p.Lys112Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067619 | c.327A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067631 | c.315C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067634 | c.312C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067652 | c.294T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067685 | c.261A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067691 | c.253_255delATCinsCG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067694 | c.252G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067718 | c.228C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067721 | c.225T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067736 | c.210C>T | synonymous_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067739 | c.207T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067761 | p.Arg62Lys | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067772 | c.174C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067799 | c.147G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067869 | p.Thr26Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067874 | c.72C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067883 | c.63C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067886 | c.60A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067889 | c.57C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067898 | p.Asp16Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073815 | c.657G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073824 | c.648A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073827 | c.645A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073839 | c.633T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073860 | c.612C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073863 | c.609T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073866 | c.606C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073872 | c.598_600delATCinsGG | frameshift_variant&missense_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073892 | c.580T>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073898 | p.Ala192Ser | missense_variant | 0.9 | para-aminosalicylic_acid | |
| thyA | 3073917 | c.555C>G | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3073920 | c.552C>G | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3073923 | c.547_549delTTGinsCA | frameshift_variant&missense_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3073947 | c.525G>A | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 0.42 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3074010 | c.462C>G | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyA | 3074013 | c.459C>T | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
| thyA | 3074028 | c.444G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074034 | c.438T>C | synonymous_variant | 0.52 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 0.48 | para-aminosalicylic_acid | |
| thyA | 3074053 | p.Arg140Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074055 | p.Glu139Pro | missense_variant | 0.54 | para-aminosalicylic_acid | |
| thyA | 3074061 | c.411A>G | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
| thyA | 3074070 | c.402C>T | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
| thyA | 3074079 | c.393G>C | synonymous_variant | 0.74 | para-aminosalicylic_acid | |
| thyA | 3074097 | c.375C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074100 | c.370_372delGATinsAC | frameshift_variant&synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3074106 | c.366T>C | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
| thyA | 3074127 | c.345G>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3074130 | c.342G>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3074172 | c.300G>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3074175 | c.297A>G | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3074181 | c.291A>G | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyA | 3074187 | c.285T>C | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyA | 3074205 | p.Glu89Asp | missense_variant | 0.97 | para-aminosalicylic_acid | |
| thyA | 3074214 | c.258T>C | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyA | 3074241 | c.231C>G | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3074244 | c.228A>G | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyA | 3074254 | p.His73Arg | missense_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3074262 | c.210T>C | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| thyA | 3074267 | p.Ile69Val | missense_variant | 0.92 | para-aminosalicylic_acid | |
| thyA | 3074268 | c.204T>C | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
| ald | 3087635 | c.816C>T | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087641 | c.822T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087647 | c.828A>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087649 | p.Gly277Asp | missense_variant | 1.0 | cycloserine | |
| ald | 3087653 | c.834A>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087656 | c.837A>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087665 | c.846C>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087666 | p.Tyr283His | missense_variant | 1.0 | cycloserine | |
| ald | 3087672 | p.His285Asp | missense_variant | 1.0 | cycloserine | |
| ald | 3087680 | c.861G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087704 | c.885T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087716 | c.897G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087726 | p.Ala303Ser | missense_variant | 1.0 | cycloserine | |
| ald | 3087729 | p.Ser304Ala | missense_variant | 1.0 | cycloserine | |
| ald | 3087737 | c.918G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087749 | c.930C>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087750 | p.Tyr311Val | missense_variant | 1.0 | cycloserine | |
| ald | 3087761 | c.942C>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087770 | c.951G>C | synonymous_variant | 1.0 | cycloserine | |
| lpqB | 3623393 | c.1518A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623411 | c.1500T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623417 | c.1494A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623423 | c.1488C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623428 | c.1483T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623441 | p.Ser490Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623444 | c.1467T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623449 | c.1462C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623456 | c.1455T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623465 | c.1446G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623468 | c.1443T>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623471 | c.1440C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623474 | c.1437C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623477 | c.1434G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623480 | c.1431C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623484 | p.Phe476Tyr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623492 | c.1419T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623512 | p.Gly467Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623528 | c.1383G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623531 | c.1380T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623549 | c.1362C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623555 | c.1354_1356delGGGinsAC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3623561 | c.1350T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623570 | c.1341A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623573 | c.1336_1338delCTTinsTG | frameshift_variant&synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3623580 | p.Asn444Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623587 | p.Ala442Pro | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623597 | c.1314C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623601 | p.Ser437Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623612 | p.Thr433Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623630 | c.1281G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623648 | c.1263A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623654 | p.Asp419Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623660 | c.1251A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623666 | c.1245A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623669 | c.1242G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623676 | p.Val412Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623681 | p.Thr410Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623684 | c.1227T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623693 | c.1218G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623703 | p.Ala403Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623705 | c.1206C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623721 | p.Ser397Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624014 | c.897T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624026 | p.Glu295Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624030 | p.Ala294Arg | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624032 | c.879T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624037 | c.874A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624041 | p.Glu290Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624050 | c.861C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624077 | c.834G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624082 | c.829A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624086 | c.825C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624092 | c.817_819delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624100 | c.811T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624101 | c.810C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624107 | c.804C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624116 | c.795A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624119 | c.792C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624124 | p.Leu263Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624125 | c.786A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624143 | c.768T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624185 | c.726C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624194 | c.717C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624200 | c.711A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624204 | p.Ser236Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624209 | c.702A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624224 | c.687T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624242 | c.669A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624245 | c.666A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624254 | c.657T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624701 | c.210T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624704 | c.207G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624707 | c.204G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624722 | c.189C>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624728 | c.183C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624755 | c.154_156delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624770 | c.141T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624776 | c.135T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624783 | p.Ser43Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624788 | c.123A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624797 | c.114T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625093 | p.Glu507Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625099 | c.-189C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625135 | c.1479A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625149 | p.Val489Ile | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625162 | c.1452T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625165 | c.-255G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625189 | c.1425A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625206 | p.Ser470Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625225 | c.-315G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625291 | c.-381A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625497 | c.1117T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625510 | c.-600T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625549 | c.-639G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625572 | p.Thr348Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625616 | p.Arg333Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625636 | c.978C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.82 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.79 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.78 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.74 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.7 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625705 | c.909C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625708 | c.906C>T | synonymous_variant | 0.32 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625711 | c.903C>T | synonymous_variant | 0.33 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.62 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625732 | c.882C>T | synonymous_variant | 0.41 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.56 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625735 | c.879C>A | synonymous_variant | 0.44 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625744 | c.870G>A | synonymous_variant | 0.45 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.52 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625750 | c.864G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.99 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625761 | p.Gln285Glu | missense_variant | 0.46 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625762 | c.852A>T | synonymous_variant | 0.46 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625774 | c.840G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625783 | c.-873C>T | upstream_gene_variant | 0.49 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625797 | p.Val273Met | missense_variant | 0.54 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625807 | c.807C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625813 | c.801C>T | synonymous_variant | 0.45 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625819 | p.Glu265Val | missense_variant | 0.44 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.58 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 0.56 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625855 | c.759G>A | synonymous_variant | 0.42 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.67 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625876 | c.738G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625882 | c.732G>A | synonymous_variant | 0.35 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625900 | c.-990G>C | upstream_gene_variant | 0.78 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625903 | c.-993G>C | upstream_gene_variant | 0.78 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 0.79 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625923 | c.691C>T | synonymous_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625927 | c.687T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625930 | c.684C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625936 | c.678C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625942 | c.672C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625945 | c.669A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625951 | c.663A>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625955 | p.Leu220Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626101 | p.Gln171His | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626110 | c.504C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626124 | p.Ala164Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626125 | c.489C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626155 | c.457_459delGCGinsTC | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3626158 | c.456C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626161 | c.453C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626170 | c.444T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626681 | c.-68C>T | upstream_gene_variant | 0.57 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626684 | c.-71G>A | upstream_gene_variant | 0.52 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626687 | c.-74G>T | upstream_gene_variant | 0.49 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626717 | c.-104C>T | upstream_gene_variant | 0.49 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626723 | c.627C>T | synonymous_variant | 0.51 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.52 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626741 | c.609C>G | synonymous_variant | 0.48 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626756 | c.594C>G | synonymous_variant | 0.5 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626762 | c.588G>C | synonymous_variant | 0.49 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.51 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.49 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.46 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.46 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626825 | c.525T>A | synonymous_variant | 0.43 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.6 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 0.36 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | c.411A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.82 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627071 | c.279G>T | synonymous_variant | 0.76 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.74 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 0.74 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.74 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627188 | c.162A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627221 | c.129C>T | synonymous_variant | 0.99 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627299 | c.49_51delTTGinsCA | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627343 | p.Thr3Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| fbiB | 3640857 | c.-678G>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640866 | c.-669T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640871 | p.Ala110Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640878 | c.-657T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640899 | c.-636G>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641938 | p.Gly135Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642656 | c.1122G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642659 | c.1125C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642668 | c.1134A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642677 | c.1143A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642680 | c.1146A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642684 | c.1150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642701 | c.1167C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| alr | 3840944 | c.477T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840947 | c.474G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840959 | c.462G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840968 | c.453G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840980 | c.441G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840989 | c.432G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840994 | p.His143Asp | missense_variant | 1.0 | cycloserine | |
| alr | 3840995 | c.424_426delTTGinsCC | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| alr | 3841001 | c.420A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841010 | c.411A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841017 | p.Leu135Glu | missense_variant | 1.0 | cycloserine | |
| alr | 3841022 | c.399C>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841028 | c.393G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841033 | p.Val130Ile | missense_variant | 1.0 | cycloserine | |
| alr | 3841037 | c.382_384delGTGinsAA | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| alr | 3841059 | p.Gly121Ala | missense_variant | 1.0 | cycloserine | |
| rpoA | 3877494 | p.Glu338Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877503 | c.1005G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877507 | p.Gly334Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 0.79 | rifampicin | |
| rpoA | 3877542 | c.966C>A | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877545 | c.963G>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877548 | c.960C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.57 | rifampicin | |
| rpoA | 3877554 | c.954G>A | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877560 | c.948C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877569 | c.937_939delCCGinsGC | frameshift_variant&missense_variant | 0.42 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877593 | c.915C>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 0.58 | rifampicin | |
| rpoA | 3877614 | c.894G>A | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877620 | c.888G>A | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877638 | c.870T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877665 | c.843C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877677 | c.829_831delGCGinsTC | frameshift_variant&missense_variant | 0.63 | rifampicin | |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877728 | c.780C>G | synonymous_variant | 0.61 | rifampicin | |
| rpoA | 3877731 | c.777G>C | synonymous_variant | 0.58 | rifampicin | |
| rpoA | 3877734 | c.774G>C | synonymous_variant | 0.6 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 0.59 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877749 | c.759C>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877752 | p.Asp252Glu | missense_variant | 0.63 | rifampicin | |
| rpoA | 3877755 | c.753C>T | synonymous_variant | 0.61 | rifampicin | |
| rpoA | 3877758 | c.750G>C | synonymous_variant | 0.61 | rifampicin | |
| rpoA | 3877764 | c.744C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877773 | c.735G>C | synonymous_variant | 0.59 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877797 | c.711G>A | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877815 | c.693C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877836 | c.672A>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>A | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877856 | c.652T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 0.49 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 0.51 | rifampicin | |
| rpoA | 3877872 | c.636C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 0.48 | rifampicin | |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877878 | c.630G>C | synonymous_variant | 0.47 | rifampicin | |
| rpoA | 3877890 | c.618C>T | synonymous_variant | 0.46 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 0.47 | rifampicin | |
| rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.47 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.54 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877923 | c.585C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 0.52 | rifampicin | |
| rpoA | 3877929 | c.577_579delATCinsGG | frameshift_variant&missense_variant | 0.47 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877974 | c.534G>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877977 | p.Lys177Asn | missense_variant | 0.33 | rifampicin | Uncertain significance |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 0.67 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 0.33 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878043 | c.465G>A | synonymous_variant | 0.63 | rifampicin | |
| rpoA | 3878050 | p.Arg153Lys | missense_variant | 0.36 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878058 | c.450G>T | synonymous_variant | 0.62 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 0.57 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878073 | c.435C>T | synonymous_variant | 0.43 | rifampicin | |
| rpoA | 3878076 | c.432C>T | synonymous_variant | 0.56 | rifampicin | |
| rpoA | 3878079 | c.429C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878082 | c.426T>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878091 | c.417C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878094 | c.414C>G | synonymous_variant | 0.49 | rifampicin | |
| rpoA | 3878102 | p.Val136Ile | missense_variant | 0.51 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 0.43 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878141 | p.Met123Leu | missense_variant | 0.42 | rifampicin | Uncertain significance |
| rpoA | 3878142 | p.Gly122Asp | missense_variant | 0.55 | rifampicin | Uncertain significance |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878181 | c.327C>T | synonymous_variant | 0.36 | rifampicin | |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 0.36 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878199 | c.309T>C | synonymous_variant | 0.42 | rifampicin | |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878226 | c.282C>G | synonymous_variant | 0.4 | rifampicin | |
| rpoA | 3878232 | c.276G>C | synonymous_variant | 0.48 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 0.48 | rifampicin | |
| rpoA | 3878259 | c.249G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Ala | missense_variant | 0.51 | rifampicin | |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878301 | c.207C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 0.49 | rifampicin | |
| rpoA | 3878310 | c.198G>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878340 | c.168C>T | synonymous_variant | 0.55 | rifampicin | |
| rpoA | 3878343 | c.165C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878376 | c.132G>C | synonymous_variant | 0.69 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 0.68 | rifampicin | |
| rpoA | 3878388 | c.120C>G | synonymous_variant | 0.69 | rifampicin | |
| rpoA | 3878391 | c.117T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878415 | c.93C>T | synonymous_variant | 0.72 | rifampicin | |
| rpoA | 3878424 | c.84G>C | synonymous_variant | 0.76 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878454 | c.54A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878484 | c.24C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878672 | c.-165A>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878683 | c.-176G>C | upstream_gene_variant | 0.83 | rifampicin | |
| rpoA | 3878713 | c.-206G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.89 | rifampicin | |
| rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.91 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
| rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878860 | c.-353C>T | upstream_gene_variant | 0.76 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878938 | c.-431T>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.89 | rifampicin | |
| rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.85 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986621 | c.-223G>C | upstream_gene_variant | 0.36 | delamanid | |
| pretomanid | ||||||
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4035679 | c.2504_*2478del | frameshift_variant&stop_lost&splice_region_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038212 | c.2493T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038239 | c.2466T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038255 | p.Val817Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038271 | p.Pro812Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038272 | c.2431_2433delGGTinsAC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038275 | c.2430A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038278 | c.2427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038293 | c.2412G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038308 | c.2397G>T | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038314 | c.2391T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038317 | c.2388G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038320 | c.2385G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038489 | p.Ala739Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038494 | c.2211G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038497 | p.Ser736Gln | missense_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038737 | c.1968C>T | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038767 | c.1938G>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038795 | p.Ser637Thr | missense_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>T | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4038838 | c.1867C>T | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4038845 | c.1858_1860delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>T | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4038923 | c.1780_1782delCTAinsTT | frameshift_variant&synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4038928 | c.1777C>A | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4038929 | c.1776G>A | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038932 | c.1773G>C | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>G | synonymous_variant | 0.57 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4039070 | c.1635G>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039077 | p.Lys543Arg | missense_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039079 | c.1626C>G | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.57 | pyrazinamide | |
| clpC1 | 4039091 | c.1614G>T | synonymous_variant | 0.58 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>T | synonymous_variant | 0.53 | pyrazinamide | |
| clpC1 | 4039196 | c.1509G>A | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039199 | p.Ala502Glu | missense_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 0.53 | pyrazinamide | |
| clpC1 | 4039220 | c.1485G>C | synonymous_variant | 0.57 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039262 | c.1443C>T | synonymous_variant | 0.64 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039265 | c.1440C>T | synonymous_variant | 0.63 | pyrazinamide | |
| clpC1 | 4039271 | c.1434G>A | synonymous_variant | 0.63 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039283 | c.1422C>T | synonymous_variant | 0.59 | pyrazinamide | |
| clpC1 | 4039286 | c.1417_1419delCTTinsTA | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039289 | c.1416T>C | synonymous_variant | 0.58 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>T | synonymous_variant | 0.6 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039304 | c.1401G>A | synonymous_variant | 0.63 | pyrazinamide | |
| clpC1 | 4039316 | p.Glu463Asp | missense_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.69 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039331 | c.1374C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039346 | p.Arg453Ser | missense_variant | 0.65 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039360 | p.Ser449Arg | missense_variant | 0.66 | pyrazinamide | |
| clpC1 | 4039361 | c.1344C>G | synonymous_variant | 0.66 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 0.61 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039418 | c.1287C>G | synonymous_variant | 0.6 | pyrazinamide | |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039454 | c.1251A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039472 | c.1233G>C | synonymous_variant | 0.63 | pyrazinamide | |
| clpC1 | 4039478 | c.1225_1227delCGGinsAC | frameshift_variant&missense_variant | 0.63 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>C | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.62 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039522 | c.1183C>T | synonymous_variant | 0.63 | pyrazinamide | |
| clpC1 | 4039528 | c.1177C>A | synonymous_variant | 0.63 | pyrazinamide | |
| clpC1 | 4039541 | c.1164C>G | synonymous_variant | 0.66 | pyrazinamide | |
| clpC1 | 4039544 | c.1161C>T | synonymous_variant | 0.65 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039565 | c.1140G>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039570 | p.Met379Leu | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039571 | c.1134G>A | synonymous_variant | 0.68 | pyrazinamide | |
| clpC1 | 4039574 | p.Ala377Gly | missense_variant | 0.68 | pyrazinamide | |
| clpC1 | 4039586 | c.1119G>C | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039601 | c.1104G>A | synonymous_variant | 0.71 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039619 | c.1086G>A | synonymous_variant | 0.65 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039649 | c.1056G>C | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.65 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>A | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4039739 | c.966C>G | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4039742 | c.963C>T | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039763 | c.942C>T | synonymous_variant | 0.45 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 0.51 | pyrazinamide | |
| clpC1 | 4039805 | c.900C>T | synonymous_variant | 0.45 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 0.51 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039832 | c.873C>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4039868 | c.837C>T | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039913 | c.792C>T | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.53 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4039943 | c.762G>C | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>G | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039957 | c.748C>T | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4039964 | c.741C>G | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4039975 | p.Asp244Asn | missense_variant | 0.54 | pyrazinamide | Uncertain significance |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.56 | pyrazinamide | |
| clpC1 | 4039982 | c.723G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040009 | c.696C>G | synonymous_variant | 0.55 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>C | synonymous_variant | 0.55 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>T | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4040048 | c.657C>T | synonymous_variant | 0.51 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040087 | c.618G>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4040126 | c.579C>T | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040141 | c.564C>T | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.64 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040174 | c.531C>T | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040204 | c.501G>C | synonymous_variant | 0.7 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>G | synonymous_variant | 0.7 | pyrazinamide | |
| clpC1 | 4040210 | c.495G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.85 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040231 | c.474C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040246 | c.459C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.87 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.74 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.68 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040300 | c.405C>T | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4040309 | c.396C>T | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.51 | pyrazinamide | |
| clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040333 | c.372G>C | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>A | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>T | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040366 | c.339C>T | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040426 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040441 | c.264C>G | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4040444 | c.261C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040456 | c.249C>T | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040462 | c.243C>T | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040495 | c.210C>T | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4040501 | c.204C>T | synonymous_variant | 0.54 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040531 | c.174T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040558 | c.147G>C | synonymous_variant | 0.51 | pyrazinamide | |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040567 | c.138C>G | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040570 | c.135C>G | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.58 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040600 | c.103_105delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043865 | c.415_417delGGAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| panD | 4043872 | p.Gly137Val | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| panD | 4043876 | p.Leu136Ile | missense_variant | 1.0 | pyrazinamide | |
| panD | 4043883 | c.399C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043886 | c.396A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043896 | p.Gly129Ala | missense_variant | 1.0 | pyrazinamide | |
| panD | 4043903 | p.Asn127Asp | missense_variant | 1.0 | pyrazinamide | |
| panD | 4043913 | c.369T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043916 | c.366A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043922 | c.360T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043931 | c.349_351delATGinsCC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| panD | 4043939 | p.Ile115Val | missense_variant | 1.0 | pyrazinamide | |
| panD | 4043951 | p.Tyr111Asp | missense_variant | 1.0 | pyrazinamide | |
| panD | 4043952 | c.330T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043961 | c.321T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043964 | c.318G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044114 | p.Val56Glu | missense_variant | 0.47 | pyrazinamide | |
| panD | 4044123 | c.159T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044138 | c.144T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044150 | c.132A>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044156 | c.126A>G | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044171 | c.111C>T | synonymous_variant | 0.57 | pyrazinamide | |
| panD | 4044174 | c.108C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044180 | p.Asp34Glu | missense_variant | 0.59 | pyrazinamide | |
| panD | 4044186 | c.94_96delTTGinsCC | frameshift_variant&missense_variant | 0.59 | pyrazinamide | Uncertain significance |
| panD | 4044189 | c.93C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044194 | p.Ala30Pro | missense_variant | 0.59 | pyrazinamide | |
| panD | 4044195 | c.87T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044232 | p.Cys17His | missense_variant | 1.0 | pyrazinamide | |
| panD | 4044234 | c.48C>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044249 | c.33C>T | synonymous_variant | 0.75 | pyrazinamide | |
| panD | 4044635 | c.-354G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044643 | c.-362G>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044647 | c.-366C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044650 | c.-369G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044662 | c.-381C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044668 | c.-387G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044672 | c.-392_-391delGCinsCA | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044675 | c.-394T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044677 | c.-396T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044682 | c.-401C>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044688 | c.-407T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044692 | c.-411G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044700 | c.-419C>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044704 | c.-423G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044712 | c.-431C>A | upstream_gene_variant | 0.96 | pyrazinamide | |
| panD | 4044725 | c.-444C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044737 | c.-456T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044746 | c.-467_-465delGTGinsAC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044752 | c.-471T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044779 | c.-500_-498delCTAinsTGC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044788 | c.-507G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044791 | c.-510G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044800 | c.-519C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044812 | c.-531A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044818 | c.-538_-537delCGinsAC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044823 | c.-542G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044833 | c.-552A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044844 | c.-563T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044848 | c.-567T>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044854 | c.-573A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044860 | c.-579C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044872 | c.-591C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044890 | c.-609G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044895 | c.-614A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044896 | c.-615T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044902 | c.-623_-621delACGinsGC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044908 | c.-628_-627delCTinsTC | upstream_gene_variant | 0.97 | pyrazinamide | |
| panD | 4044917 | c.-636G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044926 | c.-645C>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044929 | c.-648G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044935 | c.-655_-654delAAinsTG | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044941 | c.-660G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044954 | c.-674_-673delCCinsAT | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044980 | c.-699A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044983 | c.-702G>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044989 | c.-708T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045000 | c.-719A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045001 | c.-720G>C | upstream_gene_variant | 0.98 | pyrazinamide | |
| panD | 4045028 | c.-747C>G | upstream_gene_variant | 0.92 | pyrazinamide | |
| panD | 4045034 | c.-753A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045055 | c.-774T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045067 | c.-786C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045070 | c.-789C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045076 | c.-795A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045088 | c.-807T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045094 | c.-813T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045097 | c.-816T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045105 | c.-824T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045112 | c.-831A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045115 | c.-834G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045125 | c.-844T>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045127 | c.-846A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045133 | c.-852A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| glpK | 4138418 | c.1338T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138424 | c.1332T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138429 | c.1327T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138451 | c.1305T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138460 | c.1296C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138463 | c.1293C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138472 | c.1284G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138478 | c.1278T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138481 | c.1275G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138490 | c.1266G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138495 | p.Gln421Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138496 | c.1260G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138502 | c.1254T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138511 | c.1245C>T | synonymous_variant | 0.85 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138514 | c.1242A>G | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138517 | p.Glu413Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138523 | c.1233C>G | synonymous_variant | 0.77 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138529 | c.1227G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138535 | c.1221T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138559 | c.1197G>A | synonymous_variant | 0.33 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138565 | c.1191G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 0.59 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 0.59 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138580 | c.1176C>T | synonymous_variant | 0.6 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138598 | c.1158G>A | synonymous_variant | 0.53 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138601 | c.1155G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138607 | c.1149G>T | synonymous_variant | 0.85 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138610 | c.1146C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138616 | c.1140G>C | synonymous_variant | 0.5 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138622 | c.1134C>G | synonymous_variant | 0.48 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138625 | c.1131G>C | synonymous_variant | 0.48 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138625 | c.1131G>A | synonymous_variant | 0.52 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138631 | c.1125C>G | synonymous_variant | 0.44 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138634 | c.1122G>A | synonymous_variant | 0.46 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138643 | c.1113A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 0.53 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138654 | c.1102C>T | synonymous_variant | 0.52 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138664 | c.1092G>C | synonymous_variant | 0.45 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138670 | c.1086G>C | synonymous_variant | 0.55 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138695 | p.Pro354Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138712 | p.Ala348Asp | missense_variant | 0.37 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138721 | c.1035G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138724 | c.1030_1032delGCAinsTG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138730 | c.1026C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138751 | c.1005T>C | synonymous_variant | 0.4 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138763 | c.993G>A | synonymous_variant | 0.63 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138769 | c.987G>C | synonymous_variant | 0.69 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138774 | p.Ser328Ala | missense_variant | 0.67 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138778 | c.978C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138796 | c.960A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240204 | c.342T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240216 | c.354T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240558 | c.696C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240561 | c.699C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240632 | p.Met257Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4240642 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240645 | c.783G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240669 | c.807G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240677 | p.Gly272Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240685 | p.Thr275Ala | missense_variant | 0.97 | ethambutol | |
| embC | 4240693 | c.831T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240699 | c.837C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 0.8 | ethambutol | Not assoc w R - Interim |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240781 | c.919_921delGCGinsTC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240828 | c.966G>A | synonymous_variant | 0.73 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240867 | c.1005T>C | synonymous_variant | 0.72 | ethambutol | |
| embC | 4240870 | c.1008T>C | synonymous_variant | 0.72 | ethambutol | |
| embC | 4240873 | c.1011C>G | synonymous_variant | 0.72 | ethambutol | |
| embC | 4240879 | c.1017G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240880 | p.Ala340Thr | missense_variant | 0.79 | ethambutol | Uncertain significance |
| embC | 4240885 | c.1023T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240897 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240898 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 0.93 | ethambutol | |
| embC | 4240903 | c.1041C>G | synonymous_variant | 0.97 | ethambutol | |
| embC | 4240911 | p.Ala350Val | missense_variant | 0.97 | ethambutol | |
| embC | 4240921 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240924 | c.1062C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240936 | c.1074A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240945 | c.1083T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240954 | p.Ile364Met | missense_variant | 1.0 | ethambutol | |
| embC | 4240960 | c.1098G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240996 | c.1134G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241002 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241013 | p.Met384Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241032 | c.1170G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241038 | c.1176G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241047 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241053 | c.1191G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241089 | c.1227C>G | synonymous_variant | 0.92 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 0.94 | ethambutol | |
| embC | 4241107 | c.1245G>C | synonymous_variant | 0.94 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241146 | c.1284C>G | synonymous_variant | 0.93 | ethambutol | |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241170 | c.1308G>C | synonymous_variant | 0.93 | ethambutol | |
| embC | 4241173 | c.1311C>T | synonymous_variant | 0.93 | ethambutol | |
| embC | 4241203 | c.1341T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241206 | c.1344G>C | synonymous_variant | 0.91 | ethambutol | Not assoc w R - Interim |
| embC | 4241218 | c.1356G>C | synonymous_variant | 0.9 | ethambutol | |
| embC | 4241230 | c.1368A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241233 | c.1371G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241351 | p.Ile497Val | missense_variant | 1.0 | ethambutol | |
| embC | 4241361 | p.Asn500Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4241363 | c.1501_1503delCTCinsAG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4241374 | c.1512T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241380 | c.1518A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241383 | c.1521G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241392 | c.1530G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241394 | p.Lys511Ser | missense_variant | 1.0 | ethambutol | |
| embC | 4241449 | c.1587C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241453 | p.Ile531Val | missense_variant | 1.0 | ethambutol | |
| embC | 4241479 | c.1617C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241480 | c.1618T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241488 | c.1626G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241496 | p.Ala545Gly | missense_variant | 1.0 | ethambutol | |
| embC | 4241500 | c.1638A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241501 | p.Ser547Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4241506 | c.1644G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241518 | c.1656A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241521 | c.1659T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241530 | c.1668C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241536 | c.1674A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241539 | c.1677T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241545 | c.1683T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241548 | c.1686T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241551 | c.1689A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241567 | p.Ile569Val | missense_variant | 1.0 | ethambutol | |
| embC | 4241572 | c.1710C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241578 | c.1716G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241584 | c.1722T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241587 | c.1725C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241591 | p.Leu577Val | missense_variant | 1.0 | ethambutol | |
| embC | 4241611 | c.1749G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241614 | c.1752A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241626 | c.1764T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241635 | c.1773G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241995 | c.2133C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242002 | p.Leu714Val | missense_variant | 1.0 | ethambutol | |
| embC | 4242011 | c.2149_2151delCTTinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4242024 | p.Val721Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4242036 | p.Gln725Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4242045 | p.Ile728Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4242047 | p.Ser729Asp | missense_variant | 1.0 | ethambutol | |
| embC | 4242055 | c.2193C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242061 | c.2199G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242067 | c.2205G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242070 | c.2208T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242076 | c.2214G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242079 | c.2217T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242085 | c.2223A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242091 | c.2229T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242092 | c.2230T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242095 | p.Ala745Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4242106 | c.2244C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242121 | c.2259A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4242748 | c.-485A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242754 | c.-479G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242764 | p.Val968Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4242772 | c.-461G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242779 | p.Asn973Asp | missense_variant | 1.0 | ethambutol | |
| embC | 4242791 | c.2929_2931delGCAinsTC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embA | 4242796 | c.-437G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242799 | c.-434T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242820 | c.-413G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242832 | c.-401A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242838 | c.-395C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242841 | c.2979C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4242844 | c.-389A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242847 | c.-386C>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242859 | c.-374C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242862 | c.-371A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242863 | p.Tyr1001Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4242883 | c.3021C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4242892 | c.-341G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4244557 | p.Arg442Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4244582 | c.1350T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244611 | p.Ala460Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4244616 | p.Ala462Ser | missense_variant | 0.94 | ethambutol | |
| embA | 4245041 | c.1809C>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245044 | c.1812G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245053 | c.1821G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245060 | c.1828T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245083 | c.1851A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245089 | c.1857G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245101 | c.1869G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245146 | c.1914G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245153 | p.Ile641Val | missense_variant | 0.98 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245189 | c.1957C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245198 | p.Leu656Ile | missense_variant | 1.0 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245222 | c.1990_1992delTATinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245248 | c.2016G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245257 | c.2025A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245263 | c.2031A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245282 | p.Ile684Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245285 | c.2053T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245290 | c.2058C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245293 | c.2061T>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245296 | c.2064G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245299 | c.2067A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245315 | p.Val695Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4245328 | p.Ala699Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245335 | c.2103A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245340 | p.Gly703Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245345 | p.Met705Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245348 | p.Ala706Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4245355 | p.Ala708Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245368 | c.2136T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245377 | c.2145T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245388 | p.Ala719Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245401 | c.2169G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245402 | p.Thr724Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245408 | p.Leu726Ile | missense_variant | 1.0 | ethambutol | |
| embA | 4245412 | p.Ser727Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4245414 | c.2182_2184delACCinsTG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245419 | c.2187G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245423 | c.2193_2194insGCCACC | conservative_inframe_insertion | 1.0 | ethambutol | |
| embA | 4245431 | c.2199T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245434 | c.2202G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4245737 | c.-777A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245740 | c.-774T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245785 | c.2553G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245807 | c.2575_2577delTTAinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4245812 | c.-702G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245813 | c.2581_2583delCCCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245820 | p.Ser863Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4245824 | c.-690G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245833 | c.-681G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245842 | c.-672G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245845 | c.-669T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245851 | c.-663G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245860 | c.-654C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246064 | c.-450T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246076 | c.-438G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246080 | c.2848_2850delCCTinsTC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4246088 | c.2856A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embB | 4246097 | c.-417C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246103 | c.2871C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246109 | c.-405C>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246115 | c.-399T>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246128 | c.2896_2898delTCTinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4246138 | p.Arg969Gln | missense_variant | 1.0 | ethambutol | |
| embB | 4246140 | c.-374T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246143 | p.Ile971Val | missense_variant | 1.0 | ethambutol | |
| embA | 4246151 | c.2919A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4246152 | p.Ala974Gln | missense_variant | 1.0 | ethambutol | |
| embB | 4246157 | c.-357A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246164 | c.2932T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246184 | c.-330A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246196 | c.-318C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246205 | c.-309A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246292 | c.-222A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246305 | p.Ser1025Glu | missense_variant | 1.0 | ethambutol | |
| embA | 4246308 | p.Thr1026Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4246316 | c.-198T>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246319 | c.-195G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246329 | p.Thr1033Leu | missense_variant | 1.0 | ethambutol | |
| embB | 4246349 | c.-165C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246359 | c.3127_3129delGCCinsTG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4246367 | c.-147C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246373 | c.-141T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246376 | c.-138G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246379 | c.3147C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247375 | p.Leu288Val | missense_variant | 1.0 | ethambutol | |
| embB | 4247386 | c.873T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247395 | c.882C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247401 | c.888T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247407 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247434 | c.921C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247440 | c.927C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247446 | c.933C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247464 | c.951C>G | synonymous_variant | 0.97 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247579 | p.Ala356Phe | missense_variant | 1.0 | ethambutol | |
| embB | 4247587 | c.1074G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247588 | c.1075_1077delCTAinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4247603 | c.1090C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247611 | c.1098G>T | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| embB | 4247614 | c.1101T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247629 | c.1116C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247632 | c.1119C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247638 | c.1125G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247683 | c.1170C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247692 | c.1179C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247716 | c.1203C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247722 | c.1209G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247725 | c.1212G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247729 | p.Gly406Pro | missense_variant | 1.0 | ethambutol | |
| embB | 4247746 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247761 | c.1248T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247767 | c.1254G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247773 | c.1260G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247776 | c.1263G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247797 | c.1284C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247800 | c.1287A>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247803 | c.1290G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247815 | c.1302C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247819 | c.1306_1308delGTTinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4247830 | c.1317A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247839 | c.1326G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247875 | c.1362G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247876 | c.1363C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247881 | c.1368G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247887 | c.1374C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247899 | p.Met462Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4247905 | c.1392G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247909 | c.1396T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247914 | c.1401G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247932 | c.1419C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247940 | p.Leu476Trp | missense_variant | 1.0 | ethambutol | |
| embB | 4247945 | c.1432T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247951 | p.Ser480Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4247974 | c.1461C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248007 | c.1494C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248011 | p.Ser500Arg | missense_variant | 1.0 | ethambutol | |
| embB | 4248014 | p.Thr501Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4248040 | c.1527C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248041 | p.Ala510Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248044 | p.Lys511Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248172 | c.1659G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248199 | c.1686A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248205 | c.1692C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248298 | c.1785C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248304 | c.1791G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248343 | c.1830G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248350 | c.1837T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248355 | c.1842A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248358 | c.1845C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248361 | c.1848A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248362 | p.Ser617Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248373 | c.1860C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248382 | c.1869C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248386 | c.1873C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248407 | p.Leu632Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248410 | c.1897_1899delTTCinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248419 | p.Leu636Met | missense_variant | 1.0 | ethambutol | |
| embB | 4248425 | c.1912T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248430 | c.1917T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248432 | p.Trp640Phe | missense_variant | 1.0 | ethambutol | |
| embB | 4248457 | c.1944T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248472 | c.1959T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248475 | c.1962G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249348 | c.2835G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249351 | c.2838C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249369 | c.2856T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249375 | c.2862G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249381 | c.2868A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249384 | c.2871G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249417 | c.2904A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249423 | p.Asp970Glu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4249424 | p.Leu971Met | missense_variant | 1.0 | ethambutol | |
| embB | 4249429 | c.2916C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249432 | c.2919A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249441 | c.2928A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249444 | c.2931T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249447 | c.2934G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249469 | p.Leu986Met | missense_variant | 1.0 | ethambutol | |
| embB | 4249486 | c.2973T>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249498 | c.2985G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249521 | p.Ala1003Val | missense_variant | 1.0 | ethambutol | |
| embB | 4249525 | c.3012T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249529 | p.Ile1006Val | missense_variant | 1.0 | ethambutol | |
| embB | 4249532 | p.Ala1007Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4249537 | c.3024A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249543 | c.3030G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249546 | c.3033G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249558 | c.3045A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249568 | p.Ser1019Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4249573 | c.3060T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249580 | p.Leu1023Met | missense_variant | 1.0 | ethambutol | |
| embB | 4249594 | c.3081G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267241 | c.1596G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267244 | c.1593T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267256 | c.1581C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267262 | c.1575T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267266 | p.Ala524Gly | missense_variant | 1.0 | ethambutol | |
| aftB | 4267268 | c.1569T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267274 | c.1563G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267289 | p.Ala516Gln | missense_variant | 1.0 | ethambutol | |
| aftB | 4267292 | c.1545C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267297 | c.1540T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267301 | c.1536C>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267304 | p.Val511Ala | missense_variant | 1.0 | ethambutol | |
| aftB | 4267316 | c.1521A>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267325 | c.1512G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267334 | c.1503T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4267355 | c.1480_1482delCTAinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4268081 | c.756A>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268084 | c.753G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268096 | c.741C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268099 | c.738G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268102 | c.735C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268105 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268117 | c.720G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268123 | c.712_714delAGTinsGC | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4268129 | c.708T>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268138 | c.699A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268144 | c.693T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268164 | p.Gln225Glu | missense_variant | 1.0 | ethambutol | |
| aftB | 4268169 | p.Ala223Gly | missense_variant | 1.0 | ethambutol | |
| aftB | 4268171 | c.666G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268179 | c.658T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268182 | p.Phe219Leu | missense_variant | 1.0 | ethambutol | |
| aftB | 4268183 | c.654A>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268186 | c.651C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268193 | p.Leu215Ala | missense_variant | 1.0 | ethambutol | |
| aftB | 4268205 | p.Val211Ala | missense_variant | 1.0 | ethambutol | |
| aftB | 4268213 | c.624T>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268225 | c.612G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268236 | c.601T>C | synonymous_variant | 1.0 | ethambutol | |
| ubiA | 4269329 | p.Lys169Glu | missense_variant | 1.0 | ethambutol | |
| aftB | 4269342 | c.-506G>C | upstream_gene_variant | 1.0 | ethambutol |
