TB-Profiler result

Run: 3a943769-1df3-4fcd-a3a2-fc0a5e3ab008

Summary

Run ID: 3a943769-1df3-4fcd-a3a2-fc0a5e3ab008

Sample name:

Date: 08-06-2023 12:42:58

Number of reads: 40495

Percentage reads mapped: 23.24

Median coverage: 5

Strain:

Spoligotype:

Drug-resistance: MDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.7
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser428Arg Assoc w R - interim
p.Ser472Ala Uncertain significance
isoniazid kasA p.Arg121Lys Uncertain significance
ethambutol embB p.Met423Ile Uncertain significance
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin
amikacin
kanamycin
capreomycin tlyA c.235delA Uncertain significance
clofazimine
ethionamide
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761090 p.Ser428Arg missense_variant 0.79 rifampicin Assoc w R - interim
rpoB 761220 p.Ser472Ala missense_variant 0.88 rifampicin Uncertain significance
tlyA 1918173 c.235delA frameshift_variant 0.73 capreomycin Uncertain significance
kasA 2518476 p.Arg121Lys missense_variant 0.89 isoniazid Uncertain significance
embB 4247782 p.Met423Ile missense_variant 0.82 ethambutol Uncertain significance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5199 c.-41T>G upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5237 c.-2delT upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5254 c.15A>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5260 p.Lys7Asn missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5272 c.33A>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5281 c.42T>C synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5283 p.Ala15Asp missense_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5287 c.48T>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5292 p.Thr18Lys missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5294 p.Ile19Val missense_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5305 c.66G>A synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5317 c.78C>T synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5320 c.81C>T synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5341 c.102T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5344 c.105C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5347 c.108G>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5359 c.120C>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5363 c.124_126delTTAinsCTG synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5371 c.132T>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5375 p.Ile46Val missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5386 c.147G>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5401 c.162C>A synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5422 c.183T>C synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5425 c.186A>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5427 p.Thr63Ser missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5430 p.Thr64Lys missense_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5434 c.195G>C synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5435 p.Asn66Asp missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5444 p.Leu69Ile missense_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5449 c.210T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5461 c.222T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5464 c.225C>T synonymous_variant 0.7 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5465 p.Glu76Gln missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5471 p.Ala78Thr missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 5488 c.249C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5497 c.258C>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5502 p.Thr88Met missense_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5509 c.270C>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5510 p.Ser91Thr missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5515 c.276C>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5518 c.279A>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5530 c.291C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5533 c.294G>C synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5542 c.303A>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5543 p.Gln102Val missense_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5548 c.309A>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5551 c.312T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5569 p.Asp110Glu missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5570 p.Ser111Glu missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5578 c.339G>C synonymous_variant 0.7 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5581 c.342T>C synonymous_variant 0.7 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5585 p.Ile116Val missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5590 c.351T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5593 c.354T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5608 c.369C>G synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5611 c.372C>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5617 c.378G>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5623 c.384T>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5629 c.390G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5632 c.393A>G synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5635 c.396C>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5647 c.408A>G synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5649 p.Val137Ala missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5653 p.Glu138Asp missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5659 c.421_423delCGC conservative_inframe_deletion 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5668 c.429G>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5679 p.Ser147Phe missense_variant 0.81 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 5684 p.Val149Thr missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5689 c.450T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5692 p.Glu151Asp missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5695 p.Lys152Asn missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5700 p.Glu154Val missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5703 c.465_467delCCT disruptive_inframe_deletion 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5724 p.Ala162Val missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5726 p.Pro163Thr missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5727 c.488_489insAA frameshift_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5731 c.492C>A synonymous_variant 0.72 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5734 p.Lys165Asn missense_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5740 c.501G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5743 c.504G>T synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5744 p.Ser169Thr missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5749 c.510G>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5750 p.Val171Ile missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5772 p.Ala178Asp missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5776 c.537T>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5782 c.543A>G synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5790 p.Glu184Val missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5803 c.564A>G synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5807 p.Val190Ile missense_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5815 c.576C>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5818 c.579G>T synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5824 c.585A>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5833 c.594G>C synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5854 c.615C>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5858 p.Asn207Asp missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 5863 c.624G>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5873 c.634A>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5879 p.Thr214Ser missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5884 c.645A>G synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5887 p.Asp216Glu missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5902 c.663A>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5909 p.Ser224Ala missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5915 p.Val226Thr missense_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5922 p.Glu228Ala missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5932 c.693G>A synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5946 c.708delC frameshift_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5950 c.711A>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5956 c.717A>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5957 p.Ser240Ala missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5960 p.Thr241Ala missense_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5965 c.726A>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5968 c.729G>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5974 c.735A>G synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5977 c.738T>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5981 p.Ser248Arg missense_variant 0.73 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5986 c.747C>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5992 c.753T>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5998 c.759T>C synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6004 c.765T>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6007 c.768C>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6013 c.774G>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6022 c.783G>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6025 c.786A>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6091 c.852G>T synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6100 c.861G>C synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6115 c.876A>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6121 c.882C>T synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6127 c.888G>T synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6130 c.891T>C synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6142 c.903G>C synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6148 c.909C>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6160 c.921C>G synonymous_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6169 c.930C>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6181 c.942C>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6196 c.957C>T synonymous_variant 0.7 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6208 c.969G>C synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6214 c.975G>C synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6250 c.1011A>C synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6307 c.-995T>G upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6310 c.-992G>C upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6329 p.Glu364Gln missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6343 c.-959G>A upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6364 p.Leu375Phe missense_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6398 p.Val387Ile missense_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6433 c.-869C>G upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6436 c.-866C>T upstream_gene_variant 0.71 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6440 p.Thr401Ala missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 6445 p.Asp402Glu missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 6448 c.-854G>C upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6453 p.Val405Ala missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6457 c.-845T>G upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6466 c.-836G>A upstream_gene_variant 0.71 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6469 c.-833T>A upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6472 c.-830G>T upstream_gene_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6475 c.-827C>A upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6484 c.-818A>G upstream_gene_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6487 c.-815C>G upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6502 c.-800T>C upstream_gene_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6515 c.-787T>C upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6520 c.-782G>C upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6550 c.-752A>C upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6551 c.-751T>C upstream_gene_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6565 c.-737G>C upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6568 c.-734C>G upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6577 c.-725T>C upstream_gene_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.73 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6715 c.-587C>T upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6751 c.-551G>C upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6763 c.-539G>C upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6775 c.-527G>C upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6793 c.-509T>C upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6797 p.Gly520Ser missense_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6811 c.-491C>T upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6824 c.-478C>T upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6841 c.-461T>C upstream_gene_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6844 c.-458T>C upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6856 c.-446T>C upstream_gene_variant 0.71 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6859 c.-443T>C upstream_gene_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6865 c.-437G>C upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6878 c.-424T>C upstream_gene_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6881 c.-421T>C upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6896 p.Arg553Lys missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6905 p.Ile556Val missense_variant 0.87 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6911 p.Asn558His missense_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6919 c.-383T>C upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6920 p.Val561Ile missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6925 c.-377T>C upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6926 c.-376T>C upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6931 c.-371A>C upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6970 p.Asp577Glu missense_variant 0.73 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6982 c.-320A>G upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7012 c.-290G>C upstream_gene_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7037 p.Lys600Arg missense_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7045 c.-257C>T upstream_gene_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7046 p.Lys603Val missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7057 c.-245C>T upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7060 c.-242T>C upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7066 c.-236G>T upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7093 c.-209T>C upstream_gene_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7100 c.-202T>C upstream_gene_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7135 c.-167G>C upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7138 c.-164G>A upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7153 c.-149G>C upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7156 c.-146C>T upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7159 c.-143C>T upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7198 c.-104C>T upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7213 c.-89G>C upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7216 c.-86G>C upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7222 c.-80C>T upstream_gene_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7231 c.-71C>G upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7246 c.-56T>C upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7261 c.-41T>C upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7264 c.-38C>T upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7299 c.-3T>C upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7301 c.-1G>C upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7307 c.6A>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7313 c.12G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7322 c.21G>A synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7325 c.24T>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7327 p.Asp9Gly missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7343 c.42G>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7355 c.54T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7361 c.60C>T synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7367 p.Gln22His missense_variant 0.88 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7394 c.93T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7397 c.96G>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7421 c.120G>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7436 c.135C>T synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7442 c.141G>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7457 c.156T>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7460 c.159C>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7463 c.162G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7472 c.171T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7475 c.174A>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7480 p.Phe60Tyr missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7484 c.183T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7487 c.186C>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7520 c.219G>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7523 c.222C>A synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7526 c.225G>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7532 c.231T>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7541 c.240C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7547 c.246C>T synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7559 c.258G>A synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7569 p.Ala90Ser missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7585 p.Ser95Thr missense_variant 0.97 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7592 c.291G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7595 c.294C>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7614 c.313C>T synonymous_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7631 c.330G>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7643 c.342C>A synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7655 c.354G>A synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7658 c.357A>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7661 c.360C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7664 c.363T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7670 c.369A>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7685 p.Arg128Ser missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7694 c.393A>G synonymous_variant 0.72 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7706 c.405C>G synonymous_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7710 c.409T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7715 c.414G>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7725 c.424C>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7728 c.427A>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7754 p.Asp151Glu missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7763 c.462T>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7784 c.483A>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7787 c.486G>A synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7790 c.489G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7793 c.492G>C synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7799 c.498A>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7802 c.501C>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7835 c.534A>G synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7841 c.540C>T synonymous_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7847 c.546G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7859 c.558A>C synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7862 c.561C>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7865 c.564T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7906 p.Phe202Tyr missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7919 c.618G>A synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7922 c.621T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7928 p.Asp209Glu missense_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7934 c.633C>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7942 p.Glu214Ala missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7959 p.Met220Val missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7970 c.669T>C synonymous_variant 0.72 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7973 c.672A>G synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7979 c.678G>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7988 c.687G>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7992 p.Ala231Ser missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7997 c.696A>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8022 p.Ala241Thr missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8023 c.723delT frameshift_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8027 c.726T>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8035 p.Lys245Thr missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8039 c.738T>C synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8054 c.753T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8057 c.756A>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8066 c.765A>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8072 c.771T>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8076 p.Val259Ile missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8084 c.783G>A synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8087 c.786T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8088 c.787_788delTCinsAG synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8093 c.792C>G synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8096 c.795T>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8099 c.798T>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8108 c.807G>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8111 c.810G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8120 c.819G>A synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8121 c.820T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8126 c.825G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8129 c.828T>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8156 c.855T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8168 c.867A>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8174 c.873C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8177 c.876A>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8198 c.897T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8207 c.906T>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8219 c.918T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8225 c.924T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8234 c.933T>A synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8240 c.939C>A synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8243 c.942C>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8246 c.945C>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8247 p.Ile316Val missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8267 c.966G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8270 c.969G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8288 c.987T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8294 c.993T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8337 c.1036_1038delCTAinsTTG synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8360 c.1059G>A synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8366 c.1065G>A synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8382 p.Leu361Met missense_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8426 c.1125G>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8429 c.1128C>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8489 c.1188A>G synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8492 c.1191G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8495 c.1194C>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8501 c.1200G>A synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8519 c.1218A>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8531 c.1230G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8543 c.1242C>A synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8585 c.1284C>T synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8624 c.1323G>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8630 c.1329G>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8633 c.1332C>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8655 p.Ile452Val missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8738 c.1437G>T synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8750 c.1449C>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8762 c.1461G>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8765 p.Asp488Glu missense_variant 0.83 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8767 p.Arg489Lys missense_variant 0.92 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8783 c.1482G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8786 c.1485T>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.93 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8819 c.1518C>T synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8849 c.1548C>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8873 c.1572A>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8894 c.1593C>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8900 c.1599G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8903 c.1602T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8915 c.1614A>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8936 c.1635G>A synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9017 c.1716C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9044 c.1743C>T synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9060 p.Ala587Thr missense_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9077 c.1776C>T synonymous_variant 0.72 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9092 c.1791C>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9098 c.1797G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9113 c.1812C>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9145 p.Arg615Gln missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9147 c.1846_1847insA frameshift_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9191 c.1890G>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.73 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9208 p.Lys636Arg missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9213 p.Thr638Val missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9227 c.1926C>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9266 p.Asp655Glu missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9304 p.Gly668Asp missense_variant 0.96 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9368 c.2067G>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9369 c.2068C>T synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9374 c.2073G>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9383 c.2082T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9398 c.2097T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9420 p.Ile707Glu missense_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9425 c.2124C>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9440 c.2139G>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9443 c.2142G>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9453 c.2153_2155delGTG disruptive_inframe_deletion 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9464 c.2163C>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9476 c.2175G>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9482 c.2181G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9483 p.Ser728Ala missense_variant 0.91 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9500 c.2199A>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9503 c.2202T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9515 p.Glu738Asp missense_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9522 p.Pro741Thr missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9527 c.2226A>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9533 c.2232C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9536 c.2235C>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9542 c.2241T>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9545 c.2244A>G synonymous_variant 0.73 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9548 c.2247T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9549 p.Val750Ile missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9573 p.Arg758Lys missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9578 c.2277C>T synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9585 c.2284T>C synonymous_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9597 c.2296T>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9608 c.2307C>T synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9614 p.Asp771Glu missense_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9626 c.2325T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9630 p.Val777Ile missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9641 c.2340C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9662 c.2361G>T synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9668 c.2367C>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9680 c.2379G>A synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9683 c.2382G>T synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9686 c.2385A>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9689 c.2388G>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9701 c.2400T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9707 c.2406G>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9716 c.2415T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9740 p.Leu813Phe missense_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9743 c.2442C>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9746 c.2445C>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9761 c.2460A>G synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
mshA 575153 c.-195C>G upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 575154 c.-194G>C upstream_gene_variant 0.85 ethionamide
isoniazid
mshA 575159 c.-189C>G upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 575162 c.-186T>C upstream_gene_variant 0.85 ethionamide
isoniazid
mshA 575168 c.-180C>T upstream_gene_variant 0.83 ethionamide
isoniazid
mshA 575177 c.-171G>C upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575189 c.-159G>T upstream_gene_variant 0.83 ethionamide
isoniazid
mshA 575192 c.-156A>C upstream_gene_variant 0.79 ethionamide
isoniazid
mshA 575201 c.-147G>T upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 575204 c.-144C>G upstream_gene_variant 0.83 ethionamide
isoniazid
mshA 575207 c.-141A>G upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 575208 c.-140A>G upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 575213 c.-135G>T upstream_gene_variant 0.85 ethionamide
isoniazid
mshA 575219 c.-129T>C upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 575222 c.-126C>G upstream_gene_variant 0.81 ethionamide
isoniazid
mshA 575229 c.-119_-117delTTGinsATC upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 575234 c.-114T>C upstream_gene_variant 0.8 ethionamide Uncertain significance
isoniazid
mshA 575237 c.-111C>T upstream_gene_variant 0.77 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575238 c.-110T>A upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 575392 c.45G>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 575397 c.51delT frameshift_variant 0.85 ethionamide
isoniazid
mshA 575427 p.Ser27* stop_gained 0.77 ethionamide
isoniazid
mshA 575434 c.87C>T synonymous_variant 0.75 ethionamide
isoniazid
mshA 575485 c.138G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575492 p.Leu49Val missense_variant 0.91 ethionamide
isoniazid
mshA 575495 p.Leu50Ile missense_variant 0.88 ethionamide
isoniazid
mshA 575498 p.Ala51Ser missense_variant 0.86 ethionamide
isoniazid
mshA 575503 c.156G>A synonymous_variant 0.81 ethionamide
isoniazid
mshA 575512 c.165A>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 575521 c.174A>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.89 ethionamide
isoniazid
mshA 575548 c.201C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575554 c.207C>T synonymous_variant 0.91 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.93 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.91 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.93 ethionamide
isoniazid
mshA 575581 p.His78Gln missense_variant 0.91 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575593 c.246G>T synonymous_variant 0.88 ethionamide
isoniazid
mshA 575597 p.Ile84Val missense_variant 0.98 ethionamide
isoniazid
mshA 575609 p.Ile88Val missense_variant 0.9 ethionamide
isoniazid
mshA 575618 c.271C>A synonymous_variant 0.86 ethionamide
isoniazid
mshA 575627 p.Ala94Ser missense_variant 0.9 ethionamide
isoniazid
mshA 575633 p.Ala96Ser missense_variant 0.89 ethionamide
isoniazid
mshA 575641 c.294A>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575652 p.Arg102Pro missense_variant 0.95 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 575669 c.322C>T synonymous_variant 0.8 ethionamide
isoniazid
mshA 575680 c.333C>T synonymous_variant 0.84 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575704 c.357T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575728 c.381C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.96 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 0.84 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.85 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.92 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.83 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575869 c.522G>T synonymous_variant 0.85 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 0.8 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.84 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575890 c.543C>A synonymous_variant 0.89 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575905 c.558G>T synonymous_variant 0.96 ethionamide
isoniazid
mshA 575906 p.Ala187Ser missense_variant 0.96 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 0.96 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.96 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.79 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 575977 c.630G>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 575983 c.636G>A synonymous_variant 0.89 ethionamide
isoniazid
mshA 575984 c.637_639delTTGinsCTC synonymous_variant 0.91 ethionamide
isoniazid
mshA 576001 p.Asp218Glu missense_variant 0.84 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576002 p.Asp219His missense_variant 0.9 ethionamide
isoniazid
mshA 576016 c.669A>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 576020 p.Ile225Val missense_variant 0.91 ethionamide
isoniazid
mshA 576028 c.681T>G synonymous_variant 0.86 ethionamide
isoniazid
mshA 576031 c.684T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576032 p.Gly229His missense_variant 0.86 ethionamide
isoniazid
mshA 576045 p.Ala233Gly missense_variant 0.95 ethionamide
isoniazid
mshA 576049 c.702A>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 576055 c.708C>T synonymous_variant 0.86 ethionamide
isoniazid
mshA 576058 c.711G>A synonymous_variant 0.82 ethionamide
isoniazid
mshA 576061 c.714C>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 576070 c.723T>G synonymous_variant 0.82 ethionamide
isoniazid
mshA 576073 c.726C>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 576076 c.729T>C synonymous_variant 0.85 ethionamide
isoniazid
mshA 576077 c.730C>T synonymous_variant 0.75 ethionamide
isoniazid
mshA 576082 c.735C>T synonymous_variant 0.89 ethionamide
isoniazid
mshA 576084 p.Val246Ala missense_variant 0.87 ethionamide
isoniazid
mshA 576120 p.Ala258Val missense_variant 0.88 ethionamide
isoniazid
mshA 576124 c.777A>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 576128 c.781C>T synonymous_variant 0.85 ethionamide
isoniazid
mshA 576144 p.Arg266Gln missense_variant 0.78 ethionamide
isoniazid
mshA 576154 c.807C>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 576160 c.813C>G synonymous_variant 0.82 ethionamide
isoniazid
mshA 576163 c.816A>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 576166 c.819C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 576178 c.831G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 576184 c.837A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 576191 p.Ile282Val missense_variant 0.82 ethionamide
isoniazid
mshA 576202 c.855T>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 576205 c.858G>T synonymous_variant 0.98 ethionamide
isoniazid
mshA 576214 c.867G>A synonymous_variant 0.9 ethionamide
isoniazid
mshA 576215 c.868T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 576226 c.879G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 576229 c.882C>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 576230 p.Ile295Val missense_variant 0.95 ethionamide
isoniazid
mshA 576233 p.Ile296Leu missense_variant 0.87 ethionamide
isoniazid
mshA 576238 c.891G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 576247 c.900A>G synonymous_variant 0.82 ethionamide
isoniazid
mshA 576250 c.903G>A synonymous_variant 0.89 ethionamide
isoniazid
mshA 576259 c.912C>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 576262 c.915T>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 576268 c.921T>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 576269 p.Ser308Ala missense_variant 0.77 ethionamide
isoniazid
mshA 576278 p.Gly311Thr missense_variant 0.87 ethionamide
isoniazid
mshA 576286 c.939C>T synonymous_variant 0.86 ethionamide
isoniazid
mshA 576289 c.942G>T synonymous_variant 0.93 ethionamide
isoniazid
mshA 576292 c.945C>T synonymous_variant 0.91 ethionamide
isoniazid
mshA 576307 c.960C>T synonymous_variant 0.84 ethionamide
isoniazid
mshA 576311 p.Ser322Thr missense_variant 0.89 ethionamide
isoniazid
mshA 576315 p.Ala323Glu missense_variant 0.76 ethionamide
isoniazid
mshA 576319 c.972G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 576328 c.981T>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 576334 c.987G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 576345 p.His333Arg missense_variant 0.86 ethionamide
isoniazid
mshA 576349 c.1002G>A synonymous_variant 0.7 ethionamide
isoniazid
mshA 576357 p.Ala337Val missense_variant 0.88 ethionamide
isoniazid
mshA 576360 p.Thr338Asn missense_variant 0.93 ethionamide
isoniazid
mshA 576362 p.Leu339Val missense_variant 0.88 ethionamide
isoniazid
mshA 576366 p.Phe340Tyr missense_variant 0.93 ethionamide
isoniazid
mshA 576370 c.1023G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 576373 c.1026G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 576376 c.1029G>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576379 c.1032C>T synonymous_variant 0.93 ethionamide
isoniazid
mshA 576385 c.1038T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576394 c.1047G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 576421 c.1074T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 576424 c.1077T>G synonymous_variant 0.88 ethionamide
isoniazid
mshA 576425 p.Val360Ile missense_variant 0.9 ethionamide
isoniazid
mshA 576436 c.1089A>G synonymous_variant 0.83 ethionamide
isoniazid
mshA 576439 c.1092G>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 576445 c.1098C>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 576448 c.1101A>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 576460 c.1113C>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 576463 c.1116G>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 576469 c.1122G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 576475 c.1128G>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 576481 c.1134C>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 576491 p.Arg382Ala missense_variant 0.86 ethionamide
isoniazid
mshA 576500 p.Ile385Val missense_variant 0.88 ethionamide
isoniazid
mshA 576504 p.Thr386Ser missense_variant 0.92 ethionamide
isoniazid
mshA 576509 p.Thr388Ala missense_variant 0.91 ethionamide Uncertain significance
isoniazid
mshA 576517 c.1170G>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 576518 p.Ser391Asp missense_variant 0.88 ethionamide
isoniazid
mshA 576523 c.1176G>A synonymous_variant 0.88 ethionamide
isoniazid
mshA 576529 p.Glu394Asp missense_variant 0.89 ethionamide
isoniazid
mshA 576534 p.Gly396Asp missense_variant 0.82 ethionamide
isoniazid
mshA 576536 p.Gln397Asp missense_variant 0.8 ethionamide
isoniazid
mshA 576544 c.1197C>G synonymous_variant 0.76 ethionamide
isoniazid
mshA 576546 p.Asp400Ala missense_variant 0.84 ethionamide
isoniazid
mshA 576572 p.Cys409Arg missense_variant 0.86 ethionamide
isoniazid
mshA 576582 p.Pro412Gln missense_variant 0.88 ethionamide
isoniazid
mshA 576599 p.Ser418Arg missense_variant 0.93 ethionamide
isoniazid
mshA 576613 c.1266A>G synonymous_variant 0.86 ethionamide
isoniazid
mshA 576634 c.1287G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 576639 p.Glu431Ala missense_variant 0.93 ethionamide
isoniazid
mshA 576641 p.Asn432His missense_variant 0.93 ethionamide
isoniazid
mshA 576647 p.Thr434Val missense_variant 0.94 ethionamide
isoniazid
mshA 576655 c.1308G>C synonymous_variant 0.84 ethionamide
isoniazid
mshA 576659 c.1312T>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 576662 p.Ala439Asn missense_variant 0.84 ethionamide
isoniazid
mshA 576667 c.1320T>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 576671 p.Arg442Ala missense_variant 0.8 ethionamide
isoniazid
mshA 576675 p.Arg443His missense_variant 0.86 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576679 c.1332G>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 576682 p.Ile445Met missense_variant 0.81 ethionamide
isoniazid
mshA 576748 c.1402_1403delAA frameshift_variant 0.89 ethionamide
isoniazid
ccsA 619696 c.-195C>T upstream_gene_variant 0.85 capreomycin
amikacin
ccsA 619697 c.-194_-192delAGGinsCGA upstream_gene_variant 0.92 capreomycin
amikacin
ccsA 619706 c.-185_-183delGTGinsATC upstream_gene_variant 0.89 capreomycin
amikacin
ccsA 619713 c.-178_-177delCGinsTT upstream_gene_variant 0.81 capreomycin
amikacin
ccsA 619722 c.-169C>A upstream_gene_variant 0.77 capreomycin
amikacin
ccsA 619725 c.-166C>T upstream_gene_variant 0.79 capreomycin
amikacin
ccsA 619726 c.-164delA upstream_gene_variant 0.91 capreomycin
amikacin
ccsA 619729 c.-162G>T upstream_gene_variant 0.91 capreomycin
amikacin
ccsA 619730 c.-161_-159delACCinsCCA upstream_gene_variant 0.88 capreomycin
amikacin
ccsA 619735 c.-156G>A upstream_gene_variant 0.83 capreomycin
amikacin
ccsA 619744 c.-147A>G upstream_gene_variant 0.89 capreomycin
amikacin
ccsA 619762 c.-129C>G upstream_gene_variant 0.81 capreomycin
amikacin
ccsA 619766 c.-125_-123delACGinsGCC upstream_gene_variant 0.88 capreomycin
amikacin
ccsA 619771 c.-120C>T upstream_gene_variant 0.8 capreomycin
amikacin
ccsA 619786 c.-105G>C upstream_gene_variant 0.88 capreomycin
amikacin
ccsA 619794 c.-97_-96delCCinsAT upstream_gene_variant 0.93 capreomycin
amikacin
ccsA 619805 c.-86_-85delCGinsAA upstream_gene_variant 0.87 capreomycin
amikacin
ccsA 619815 c.-76G>A upstream_gene_variant 0.74 capreomycin
amikacin
ccsA 619827 c.-64C>A upstream_gene_variant 0.87 capreomycin
amikacin
ccsA 619831 c.-60T>C upstream_gene_variant 0.91 capreomycin
amikacin
ccsA 619874 c.-16_-14delCCG upstream_gene_variant 0.88 capreomycin
amikacin
ccsA 619887 c.-4T>G upstream_gene_variant 0.81 capreomycin
amikacin
ccsA 619891 c.1T>G start_lost 0.89 capreomycin
amikacin
ccsA 619896 c.6C>T synonymous_variant 0.86 capreomycin
amikacin
ccsA 619899 c.9G>C synonymous_variant 0.85 capreomycin
amikacin
ccsA 619900 p.Leu4Glu missense_variant 0.85 capreomycin
amikacin
ccsA 619906 p.Val6Ile missense_variant 0.87 capreomycin
amikacin
ccsA 619909 p.Asn7Asp missense_variant 0.85 capreomycin
amikacin
ccsA 619912 p.Val8Ile missense_variant 0.85 capreomycin
amikacin
ccsA 619917 c.27C>G synonymous_variant 0.78 capreomycin
amikacin
ccsA 619920 c.30G>T synonymous_variant 0.85 capreomycin
amikacin
ccsA 619924 c.34_36delCGCinsAGG synonymous_variant 0.9 capreomycin
amikacin
ccsA 619947 c.57C>G synonymous_variant 0.86 capreomycin
amikacin
ccsA 619951 p.Ala21Ser missense_variant 0.74 capreomycin
amikacin
ccsA 619961 p.Ala24Val missense_variant 0.74 capreomycin
amikacin
ccsA 619970 p.Val27Gly missense_variant 0.89 capreomycin
amikacin
ccsA 619978 p.Leu30Ile missense_variant 0.86 capreomycin
amikacin
ccsA 619986 c.96G>C synonymous_variant 0.82 capreomycin
amikacin
ccsA 619989 c.99G>C synonymous_variant 0.82 capreomycin
amikacin
ccsA 619990 p.Phe34Val missense_variant 0.88 capreomycin
amikacin
ccsA 619995 c.105G>A synonymous_variant 0.86 capreomycin
amikacin
ccsA 619996 p.Phe36Leu missense_variant 0.82 capreomycin
amikacin
ccsA 620001 c.111_112insTA frameshift_variant 0.89 capreomycin
amikacin
ccsA 620013 c.123T>C synonymous_variant 0.9 capreomycin
amikacin
ccsA 620017 p.Gly43Lys missense_variant 0.88 capreomycin
amikacin
ccsA 620020 p.Leu44Val missense_variant 0.91 capreomycin
amikacin
ccsA 620033 p.Ala48Val missense_variant 0.8 capreomycin
amikacin Uncertain significance
ccsA 620035 c.146delT frameshift_variant 0.97 capreomycin
amikacin
ccsA 620038 c.148_149insG frameshift_variant 0.97 capreomycin
amikacin
ccsA 620041 p.Ala51Thr missense_variant 0.8 capreomycin
amikacin
ccsA 620044 c.155_156delGA frameshift_variant 0.94 capreomycin
amikacin
ccsA 620052 c.163_166delGCCA frameshift_variant 0.95 capreomycin
amikacin
ccsA 620061 c.171T>C synonymous_variant 0.9 capreomycin
amikacin
ccsA 620064 c.174C>T synonymous_variant 0.83 capreomycin
amikacin
ccsA 620066 p.Ala59Val missense_variant 0.8 capreomycin
amikacin
ccsA 620076 c.186G>C synonymous_variant 0.93 capreomycin
amikacin
ccsA 620077 p.Ile63Val missense_variant 0.95 capreomycin Uncertain significance
amikacin Uncertain significance
ccsA 620082 c.192G>C synonymous_variant 0.95 capreomycin
amikacin
ccsA 620096 p.His69Arg missense_variant 0.84 capreomycin
amikacin Uncertain significance
ccsA 620112 c.222A>G synonymous_variant 0.95 capreomycin
amikacin
ccsA 620115 c.225C>G synonymous_variant 0.9 capreomycin
amikacin
ccsA 620123 p.Arg78Gln missense_variant 0.81 capreomycin
amikacin
ccsA 620126 p.Gly79Ala missense_variant 0.89 capreomycin
amikacin
ccsA 620136 c.246C>G synonymous_variant 0.74 capreomycin
amikacin
ccsA 620137 p.Val83Leu missense_variant 0.87 capreomycin
amikacin
ccsA 620140 p.Ala84Thr missense_variant 0.95 capreomycin
amikacin
ccsA 620145 c.255T>C synonymous_variant 0.84 capreomycin
amikacin
ccsA 620146 p.Leu86Val missense_variant 0.92 capreomycin
amikacin
ccsA 620157 c.267G>C synonymous_variant 0.8 capreomycin
amikacin
ccsA 620158 p.Leu90Met missense_variant 0.89 capreomycin
amikacin
ccsA 620161 c.271C>T synonymous_variant 0.92 capreomycin
amikacin
ccsA 620164 p.Leu92Phe missense_variant 0.87 capreomycin
amikacin
ccsA 620168 p.Ala93Val missense_variant 0.82 capreomycin
amikacin
ccsA 620173 p.Val95Ile missense_variant 0.87 capreomycin
amikacin
ccsA 620179 c.289C>T synonymous_variant 0.88 capreomycin
amikacin
ccsA 620196 c.306C>G synonymous_variant 0.8 capreomycin
amikacin
ccsA 620197 p.Gln103Ser missense_variant 0.8 capreomycin
amikacin
ccsA 620242 p.Cys118Ser missense_variant 0.98 capreomycin
amikacin
ccsA 620247 p.Leu119Phe missense_variant 0.9 capreomycin
amikacin Uncertain significance
ccsA 620249 p.Ser120Cys missense_variant 0.84 capreomycin
amikacin Uncertain significance
ccsA 620256 c.366C>G synonymous_variant 0.88 capreomycin
amikacin
ccsA 620264 p.Gly125Ala missense_variant 0.92 capreomycin
amikacin
ccsA 620282 p.Arg131His missense_variant 0.8 capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.76 capreomycin
amikacin Uncertain significance
ccsA 620289 c.399A>G synonymous_variant 0.98 capreomycin
amikacin
ccsA 620295 c.405G>C synonymous_variant 0.73 capreomycin
amikacin
ccsA 620296 p.Pro136Val missense_variant 0.86 capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.85 capreomycin
amikacin
ccsA 620311 p.Leu141Val missense_variant 0.89 capreomycin
amikacin Uncertain significance
ccsA 620319 c.429C>T synonymous_variant 0.88 capreomycin
amikacin
ccsA 620337 c.447C>G synonymous_variant 0.9 capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.92 capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.86 capreomycin
amikacin
ccsA 620349 c.459A>T synonymous_variant 0.89 capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 0.9 capreomycin
amikacin
ccsA 620362 p.Ala158Ser missense_variant 0.87 capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.79 capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.85 capreomycin
amikacin
ccsA 620385 c.495G>T synonymous_variant 0.93 capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.91 capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.9 capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620421 c.531G>C synonymous_variant 0.92 capreomycin
amikacin
ccsA 620427 c.537C>G synonymous_variant 0.87 capreomycin
amikacin
ccsA 620436 c.546T>C synonymous_variant 0.77 capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.92 capreomycin
amikacin
ccsA 620463 c.573C>G synonymous_variant 0.89 capreomycin
amikacin
ccsA 620481 c.591T>G synonymous_variant 0.8 capreomycin
amikacin
ccsA 620482 p.Val198Leu missense_variant 0.92 capreomycin
amikacin Uncertain significance
ccsA 620485 p.Arg199Lys missense_variant 0.86 capreomycin
amikacin
ccsA 620489 p.Thr200Met missense_variant 0.86 capreomycin
amikacin
ccsA 620495 p.Arg202Pro missense_variant 0.9 capreomycin
amikacin Uncertain significance
ccsA 620502 c.612T>C synonymous_variant 0.96 capreomycin
amikacin
ccsA 620509 p.Thr207Ala missense_variant 0.87 capreomycin
amikacin
ccsA 620524 p.Leu212Val missense_variant 0.81 capreomycin
amikacin
ccsA 620530 p.Gly214Arg missense_variant 0.75 capreomycin
amikacin Uncertain significance
ccsA 620535 p.Met215Ile missense_variant 0.91 capreomycin
amikacin
ccsA 620536 p.Val216Met missense_variant 0.77 capreomycin
amikacin
ccsA 620537 c.648delG frameshift_variant 0.92 capreomycin
amikacin
ccsA 620547 c.657C>G synonymous_variant 0.8 capreomycin
amikacin
ccsA 620553 c.663T>C synonymous_variant 0.89 capreomycin
amikacin
ccsA 620556 c.666C>G synonymous_variant 0.91 capreomycin
amikacin
ccsA 620559 c.669A>G synonymous_variant 0.92 capreomycin
amikacin
ccsA 620562 c.672C>G synonymous_variant 0.89 capreomycin
amikacin
ccsA 620569 p.Gly227Arg missense_variant 0.82 capreomycin
amikacin Uncertain significance
ccsA 620574 c.684C>T synonymous_variant 0.8 capreomycin
amikacin
ccsA 620583 c.693G>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 0.9 capreomycin
amikacin
ccsA 620605 p.Val239Ile missense_variant 0.82 capreomycin
amikacin Uncertain significance
ccsA 620613 c.723C>T synonymous_variant 0.91 capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620634 c.744C>G synonymous_variant 0.94 capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.88 capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 0.95 capreomycin
amikacin
ccsA 620670 c.780C>T synonymous_variant 0.88 capreomycin
amikacin
ccsA 620676 c.786C>T synonymous_variant 0.8 capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.93 capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.95 capreomycin
amikacin Uncertain significance
ccsA 620703 c.813G>C synonymous_variant 0.97 capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.92 capreomycin
amikacin
ccsA 620724 c.834C>T synonymous_variant 0.84 capreomycin
amikacin
ccsA 620736 c.846G>C synonymous_variant 0.87 capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.93 capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.9 capreomycin
amikacin
ccsA 620764 p.Ala292Ser missense_variant 0.8 capreomycin
amikacin
ccsA 620769 c.879C>T synonymous_variant 0.92 capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 0.92 capreomycin
amikacin
ccsA 620781 c.891C>G synonymous_variant 0.89 capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 0.94 capreomycin
amikacin Uncertain significance
ccsA 620787 c.897C>T synonymous_variant 0.9 capreomycin
amikacin
ccsA 620793 c.903G>C synonymous_variant 0.93 capreomycin
amikacin
ccsA 620796 c.906C>G synonymous_variant 0.95 capreomycin
amikacin
ccsA 620802 c.912C>G synonymous_variant 0.95 capreomycin
amikacin
ccsA 620808 c.918T>C synonymous_variant 0.93 capreomycin
amikacin
ccsA 620818 p.Val310Ile missense_variant 0.9 capreomycin
amikacin
ccsA 620835 c.945C>G synonymous_variant 0.88 capreomycin
amikacin
ccsA 620838 c.948C>T synonymous_variant 0.87 capreomycin
amikacin
ccsA 620844 c.954C>T synonymous_variant 0.83 capreomycin
amikacin
ccsA 620856 c.966C>G synonymous_variant 0.77 capreomycin
amikacin
ccsA 620859 c.969G>T synonymous_variant 0.83 capreomycin
amikacin
rpoB 759689 c.-118A>G upstream_gene_variant 0.75 rifampicin
rpoB 759711 c.-96G>A upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoB 759761 c.-46C>T upstream_gene_variant 0.73 rifampicin
rpoB 759788 c.-19A>G upstream_gene_variant 0.83 rifampicin
rpoB 759814 p.Asp3Val missense_variant 0.76 rifampicin
rpoB 759818 c.12C>T synonymous_variant 0.86 rifampicin
rpoB 759862 p.Gln19Leu missense_variant 0.76 rifampicin
rpoB 759870 p.Ser22Thr missense_variant 0.71 rifampicin
rpoB 759884 c.78A>C synonymous_variant 0.88 rifampicin
rpoB 759887 c.81C>A synonymous_variant 0.78 rifampicin
rpoB 759893 c.87G>A synonymous_variant 0.86 rifampicin
rpoB 759896 c.90A>G synonymous_variant 0.82 rifampicin
rpoB 759905 c.99C>T synonymous_variant 0.82 rifampicin
rpoB 759908 c.102C>A synonymous_variant 0.85 rifampicin
rpoB 759911 c.105C>T synonymous_variant 0.86 rifampicin
rpoB 759914 c.108T>C synonymous_variant 0.89 rifampicin
rpoB 759920 c.114G>C synonymous_variant 0.85 rifampicin
rpoB 759929 c.123A>G synonymous_variant 0.9 rifampicin
rpoB 759944 c.138A>G synonymous_variant 0.89 rifampicin
rpoB 759947 c.141C>A synonymous_variant 0.81 rifampicin
rpoB 759956 c.150C>T synonymous_variant 0.78 rifampicin
rpoB 759962 c.156C>G synonymous_variant 0.83 rifampicin
rpoB 759968 c.162G>C synonymous_variant 0.83 rifampicin
rpoB 759974 p.Glu56Asp missense_variant 0.83 rifampicin
rpoB 759981 p.Ile59Val missense_variant 0.8 rifampicin
rpoB 759986 c.180T>A synonymous_variant 0.85 rifampicin
rpoB 759987 p.Ser61Ala missense_variant 0.85 rifampicin
rpoB 759990 p.Pro62Thr missense_variant 0.75 rifampicin
rpoB 760012 p.Ala69Val missense_variant 0.79 rifampicin
rpoB 760016 p.Glu70Asp missense_variant 0.74 rifampicin
rpoB 760043 c.237C>T synonymous_variant 0.84 rifampicin
rpoB 760046 c.240G>C synonymous_variant 0.82 rifampicin
rpoB 760059 p.Tyr85Glu missense_variant 0.9 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.85 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.83 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.71 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.76 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.79 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.93 rifampicin
rpoB 760121 c.315T>C synonymous_variant 0.89 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 0.91 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.91 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.91 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.97 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.91 rifampicin
rpoB 760196 c.390C>G synonymous_variant 0.91 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.96 rifampicin
rpoB 760244 c.438G>C synonymous_variant 0.89 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.91 rifampicin
rpoB 760298 c.492G>C synonymous_variant 0.98 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.78 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.92 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.95 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.81 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.95 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.79 rifampicin
rpoB 760357 p.Thr184Ser missense_variant 0.9 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.95 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.95 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.86 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.98 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.98 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.91 rifampicin
rpoB 760478 c.672C>T synonymous_variant 0.77 rifampicin
rpoB 760481 c.675G>T synonymous_variant 0.96 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.96 rifampicin
rpoB 760502 c.696C>G synonymous_variant 0.93 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.92 rifampicin
rpoB 760533 p.Val243Thr missense_variant 0.93 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.98 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.98 rifampicin
rpoB 760561 c.757_758delCG frameshift_variant 0.89 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.91 rifampicin
rpoB 760574 c.768G>C synonymous_variant 0.75 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.96 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.97 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.96 rifampicin
rpoB 760625 c.819C>G synonymous_variant 0.93 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.88 rifampicin