TB-Profiler result

Run: SRR20969677
Summary

Run ID: SRR20969677

Sample name:

Date: 2024-10-05T13:07:41.802328

Number of reads: 4122070

Percentage reads mapped: 47.68

Median coverage: 120.0

Strain: La3;lineage2

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.95
lineage4.1.2.1.1 Euro-American (Haarlem) RD182 0.12
La1.2.BCG M.bovis None 0.34
lineage6.2.3 West-Africa 2 RD702 0.25
La1.7.1 M.bovis None 0.15
La3 M.orygis None 0.3
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
p.Ala659Thr Mutation from literature
pyrazinamide panD p.Val138Ala Mutation from literature
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
gid c.115delC Assoc w R
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance Mutation from literature
katG 2155168 p.Ser315Thr missense_variant 0.63 isoniazid Assoc w R High-level resistance
panD 4043869 p.Val138Ala missense_variant 0.35 pyrazinamide Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.7 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.75 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.52 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.58 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.55 ethambutol Mutation from literature
embB 4248488 p.Ala659Thr missense_variant 0.32 ethambutol Mutation from literature
gid 4408087 c.115delC frameshift_variant 0.97 streptomycin Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 0.28 isoniazid
dnaA 42 c.42C>T synonymous_variant 0.29 isoniazid
dnaA 51 c.51C>T synonymous_variant 0.23 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>T synonymous_variant 0.28 isoniazid
dnaA 600 c.600T>G synonymous_variant 0.33 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.46 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 649 c.649C>T synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.46 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.44 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.45 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>C synonymous_variant 0.44 isoniazid
dnaA 682 c.682T>C synonymous_variant 0.45 isoniazid
dnaA 693 c.693A>G synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.42 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.42 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.43 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.42 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.4 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.4 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.39 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.42 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCTC synonymous_variant 0.46 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.48 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.47 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.48 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.49 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.49 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.49 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.5 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.51 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.5 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.53 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.52 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.51 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.51 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.52 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.52 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.52 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.52 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.51 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.5 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.49 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.49 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.52 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.54 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.55 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.55 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.55 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 0.55 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.59 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.57 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.58 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.57 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.55 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.54 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.54 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.54 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.54 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.52 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.52 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.52 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.48 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.48 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.48 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.47 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.49 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.47 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.45 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.45 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.46 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.48 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.49 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.47 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.48 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.5 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.48 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.48 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.48 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.48 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 0.46 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.46 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.47 isoniazid
dnaA 1320 c.1320G>C synonymous_variant 0.47 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.5 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.52 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.48 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.48 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.47 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.45 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.43 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.42 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.41 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.39 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.41 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.4 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.38 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.38 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.39 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.38 isoniazid
dnaA 1485 p.Lys495Asn missense_variant 0.31 isoniazid Uncertain significance
dnaA 1488 c.1488A>G synonymous_variant 0.3 isoniazid
dnaA 1497 c.1497T>C synonymous_variant 0.24 isoniazid
gyrB 6136 c.897G>A synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.51 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.43 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.46 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6868 c.-434G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>T upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6881 c.-421_-419delTTGinsCTC upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>T upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6901 c.-401G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 7015 c.-287G>A upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7093 c.-209T>G upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7102 c.-200G>A upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7210 c.-92C>T upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7763 c.462T>C synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7775 c.474C>A synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7781 c.480G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7806 c.505C>A synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7823 c.522G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7853 c.552C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8093 c.792C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8096 c.795T>A synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8186 c.885G>A synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.49 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.52 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.48 levofloxacin
moxifloxacin
gyrA 8387 c.1086C>T synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8391 p.Tyr364His missense_variant 0.46 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>A synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>A synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318_1320delTTGinsCTA synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Arg missense_variant 0.52 levofloxacin Uncertain significance
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.51 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Ser missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.44 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.46 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.41 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8837 c.1536C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.58 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.46 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.6 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9284 c.1983T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 9428 c.2127C>T synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Tyr missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 9435 c.2134C>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9443 c.2142G>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9452 c.2151G>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9458 c.2157A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9467 c.2166T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9572 c.2271C>G synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9578 c.2277C>T synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9582 c.2281A>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9611 p.Asp770Glu missense_variant 0.41 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9638 c.2337C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 9641 c.2340C>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9665 c.2364A>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9666 p.Arg789Gly missense_variant 0.43 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9674 c.2373T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9708 c.2407T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9716 c.2415T>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9725 c.2424G>A synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 9727 p.Gly809Asp missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9755 c.2454C>T synonymous_variant 0.18 levofloxacin
moxifloxacin
Rv0010c 13852 c.-296_-294delTTAinsCTG upstream_gene_variant 0.31 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 0.31 isoniazid
Rv0010c 13864 c.-306A>G upstream_gene_variant 0.33 isoniazid
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.32 isoniazid
Rv0010c 13879 c.-321T>C upstream_gene_variant 0.34 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.31 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.32 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.29 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.29 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.29 isoniazid
fgd1 490555 c.-228G>T upstream_gene_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 490782 c.-1G>C upstream_gene_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 490797 c.15G>A synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 490800 c.18A>C synonymous_variant 0.32 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 490827 c.45C>T synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 490848 c.66A>G synonymous_variant 0.46 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 490868 p.Ala29Gly missense_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>A synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 490890 c.108C>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490896 c.114C>T synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 490917 c.135C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 490921 p.Gln47Glu missense_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 490929 c.147C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 490932 c.150T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fgd1 490935 c.153C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 490948 p.Ser56Ala missense_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 490962 c.180T>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 490977 c.195C>G synonymous_variant 0.49 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fgd1 490980 p.Asn66Lys missense_variant 0.51 pretomanid
delamanid
clofazimine
fgd1 490984 p.Leu68Ile missense_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490987 p.Leu69Thr missense_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491001 c.219G>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 0.69 pretomanid
delamanid
clofazimine
fgd1 491077 p.Asn99Asp missense_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491094 c.312C>G synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fgd1 491100 c.318C>T synonymous_variant 0.68 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491106 c.324T>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fgd1 491130 c.348C>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Asp missense_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>A synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491173 c.391C>A synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491184 c.402A>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.54 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491292 c.510G>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 0.56 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491302 p.Ile174Val missense_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491307 c.525C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491313 c.531C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491319 c.537G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491325 c.543G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491337 c.555C>G synonymous_variant 0.52 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491340 c.558C>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>C synonymous_variant 0.51 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fgd1 491367 c.585G>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491472 c.690A>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491487 c.705C>T synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491496 c.714C>T synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491499 c.717G>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491500 p.Glu240Lys missense_variant 0.34 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491509 c.727T>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 0.34 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fgd1 491535 c.753G>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fgd1 491553 c.771G>A synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.49 pretomanid
delamanid
clofazimine
fgd1 491643 c.861G>A synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 491646 c.864G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491658 c.876A>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491661 c.879C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491673 c.891A>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491676 c.894T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fgd1 491679 c.897A>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491687 p.Thr302Lys missense_variant 0.49 pretomanid
delamanid
clofazimine
fgd1 491697 c.915G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fgd1 491709 c.927A>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491712 c.930T>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491718 c.936A>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fgd1 491721 c.939A>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491724 c.942A>T synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491727 c.945T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491742 c.960T>C synonymous_variant 0.99 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
fgd1 491748 p.Glu322Asp missense_variant 0.26 pretomanid
delamanid
clofazimine
mshA 574595 c.-753A>G upstream_gene_variant 0.26 isoniazid
ethionamide
mshA 574604 c.-744C>G upstream_gene_variant 0.38 isoniazid
ethionamide
mshA 574607 c.-741G>T upstream_gene_variant 0.38 isoniazid
ethionamide
mshA 574616 c.-732G>C upstream_gene_variant 0.47 isoniazid
ethionamide
mshA 574619 c.-729C>G upstream_gene_variant 0.48 isoniazid
ethionamide
mshA 574640 c.-708G>A upstream_gene_variant 0.51 isoniazid
ethionamide
mshA 574650 c.-698A>C upstream_gene_variant 0.56 isoniazid
ethionamide
mshA 574655 c.-693C>G upstream_gene_variant 0.56 isoniazid
ethionamide
mshA 574664 c.-684G>C upstream_gene_variant 0.54 isoniazid
ethionamide
mshA 574671 c.-677_-675delGCAinsCTG upstream_gene_variant 0.53 isoniazid
ethionamide
mshA 574676 c.-672G>C upstream_gene_variant 0.52 isoniazid
ethionamide
mshA 574683 c.-665T>C upstream_gene_variant 0.51 isoniazid Uncertain significance
ethionamide
mshA 574688 c.-660G>C upstream_gene_variant 0.52 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.52 isoniazid
ethionamide
mshA 574712 c.-636A>G upstream_gene_variant 0.51 isoniazid
ethionamide
mshA 574718 c.-630A>G upstream_gene_variant 0.51 isoniazid
ethionamide
mshA 574724 c.-624T>C upstream_gene_variant 0.51 isoniazid
ethionamide
mshA 574731 c.-617A>G upstream_gene_variant 0.51 isoniazid
ethionamide
mshA 574739 c.-609T>C upstream_gene_variant 0.52 isoniazid
ethionamide
mshA 574758 c.-590G>T upstream_gene_variant 0.35 isoniazid
ethionamide
mshA 574979 c.-369G>T upstream_gene_variant 0.23 isoniazid
ethionamide
mshA 574996 c.-352C>G upstream_gene_variant 0.26 isoniazid
ethionamide
mshA 575000 c.-348C>G upstream_gene_variant 0.28 isoniazid
ethionamide
mshA 575009 c.-339T>G upstream_gene_variant 0.32 isoniazid
ethionamide
mshA 575011 c.-337G>A upstream_gene_variant 0.32 isoniazid
ethionamide
mshA 575018 c.-330C>G upstream_gene_variant 0.32 isoniazid
ethionamide
mshA 575022 c.-326C>T upstream_gene_variant 0.33 isoniazid
ethionamide
mshA 575030 c.-318T>C upstream_gene_variant 0.34 isoniazid
ethionamide
mshA 575034 c.-314_-312delTTAinsATG upstream_gene_variant 0.34 isoniazid
ethionamide
mshA 575042 c.-306T>C upstream_gene_variant 0.42 isoniazid
ethionamide
mshA 575052 c.-296G>C upstream_gene_variant 0.43 isoniazid
ethionamide
mshA 575057 c.-291G>C upstream_gene_variant 0.44 isoniazid
ethionamide
mshA 575060 c.-288G>C upstream_gene_variant 0.45 isoniazid
ethionamide
mshA 575063 c.-285T>C upstream_gene_variant 0.45 isoniazid
ethionamide
mshA 575075 c.-273T>C upstream_gene_variant 0.46 isoniazid Uncertain significance
ethionamide
mshA 575084 c.-264T>C upstream_gene_variant 0.45 isoniazid
ethionamide
mshA 575117 c.-231T>C upstream_gene_variant 0.36 isoniazid
ethionamide
mshA 575118 c.-230_-228delACGinsGCC upstream_gene_variant 0.34 isoniazid
ethionamide
mshA 575124 c.-224_-222delGGGinsCGC upstream_gene_variant 0.33 isoniazid
ethionamide
mshA 575137 c.-211C>G upstream_gene_variant 0.33 isoniazid
ethionamide
mshA 575144 c.-204T>C upstream_gene_variant 0.3 isoniazid
ethionamide
mshA 575162 c.-186T>G upstream_gene_variant 0.25 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 0.27 isoniazid
ethionamide
mshA 575542 c.195C>A synonymous_variant 0.37 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 0.45 isoniazid
ethionamide
mshA 575569 c.222A>G synonymous_variant 0.44 isoniazid
ethionamide
mshA 575571 p.Ser75Thr missense_variant 0.44 isoniazid
ethionamide
mshA 575576 c.229C>T synonymous_variant 0.49 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 0.54 isoniazid
ethionamide
mshA 575587 c.240C>G synonymous_variant 0.58 isoniazid
ethionamide
mshA 575590 c.243T>C synonymous_variant 0.59 isoniazid
ethionamide
mshA 575623 c.276C>G synonymous_variant 0.68 isoniazid
ethionamide
mshA 575629 c.282A>G synonymous_variant 0.66 isoniazid
ethionamide
mshA 575632 c.285G>C synonymous_variant 0.66 isoniazid
ethionamide
mshA 575635 c.288A>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
ethionamide
mshA 575638 c.291T>C synonymous_variant 0.66 isoniazid
ethionamide
mshA 575641 c.294A>G synonymous_variant 0.67 isoniazid
ethionamide
mshA 575647 c.300G>C synonymous_variant 0.67 isoniazid
ethionamide
mshA 575649 p.Val101Ala missense_variant 0.68 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.69 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 0.67 isoniazid
ethionamide
mshA 575665 c.318G>A synonymous_variant 0.7 isoniazid
ethionamide
mshA 575674 c.327G>C synonymous_variant 0.74 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.71 isoniazid Not assoc w R - Interim
ethionamide
mshA 575701 c.354G>A synonymous_variant 0.7 isoniazid
ethionamide
mshA 575704 c.357T>G synonymous_variant 0.69 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.69 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.71 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 0.73 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.71 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.71 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.72 isoniazid
ethionamide
mshA 575752 c.405G>C synonymous_variant 0.69 isoniazid
ethionamide
mshA 575755 c.408G>A synonymous_variant 0.68 isoniazid
ethionamide
mshA 575756 c.409C>T synonymous_variant 0.68 isoniazid
ethionamide
mshA 575770 c.423G>A synonymous_variant 0.72 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 0.71 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.7 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.69 isoniazid
ethionamide
mshA 575793 p.Asp149Gly missense_variant 0.69 isoniazid
ethionamide
mshA 575809 c.462C>T synonymous_variant 0.71 isoniazid
ethionamide
mshA 575812 c.465C>T synonymous_variant 0.74 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.72 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 0.7 isoniazid
ethionamide
mshA 575830 c.483C>G synonymous_variant 0.71 isoniazid
ethionamide
mshA 575833 c.486C>G synonymous_variant 0.72 isoniazid
ethionamide
mshA 575845 c.498C>T synonymous_variant 0.78 isoniazid Not assoc w R - Interim
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.76 isoniazid
ethionamide
mshA 575887 c.540G>C synonymous_variant 0.75 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.73 isoniazid
ethionamide
mshA 575896 c.549G>C synonymous_variant 0.71 isoniazid
ethionamide
mshA 575908 c.561A>G synonymous_variant 0.7 isoniazid
ethionamide
mshA 575917 p.Asp190Glu missense_variant 0.69 isoniazid
ethionamide
mshA 575920 c.573C>G synonymous_variant 0.68 isoniazid
ethionamide
mshA 575924 p.Gly193Ser missense_variant 0.67 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.64 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.62 isoniazid
ethionamide
mshA 575965 c.618C>G synonymous_variant 0.52 isoniazid Not assoc w R - Interim
ethionamide
mshA 575977 c.630G>C synonymous_variant 0.41 isoniazid
ethionamide
mshA 575980 c.633T>C synonymous_variant 0.41 isoniazid
ethionamide
mshA 575984 c.637T>C synonymous_variant 0.41 isoniazid
ethionamide
mshA 576004 c.657T>C synonymous_variant 0.24 isoniazid
ethionamide
mshA 576184 c.837A>C synonymous_variant 0.38 isoniazid
ethionamide
mshA 576193 c.846T>C synonymous_variant 0.35 isoniazid
ethionamide
mshA 576197 c.850C>T synonymous_variant 0.34 isoniazid
ethionamide
mshA 576205 c.858G>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
ethionamide
mshA 576208 c.861C>G synonymous_variant 0.35 isoniazid
ethionamide
mshA 576211 c.864C>G synonymous_variant 0.36 isoniazid
ethionamide
mshA 576214 c.867G>A synonymous_variant 0.35 isoniazid
ethionamide
mshA 576215 c.868T>C synonymous_variant 0.36 isoniazid
ethionamide
mshA 576229 c.882C>G synonymous_variant 0.33 isoniazid
ethionamide
mshA 576233 p.Ile296Val missense_variant 0.33 isoniazid
ethionamide
mshA 576241 c.894C>G synonymous_variant 0.3 isoniazid
ethionamide
mshA 576262 c.915T>C synonymous_variant 0.26 isoniazid
ethionamide
mshA 576271 c.924A>C synonymous_variant 0.27 isoniazid
ethionamide
mshA 576281 c.934C>T synonymous_variant 0.26 isoniazid Not assoc w R - Interim
ethionamide
mshA 576289 c.942G>C synonymous_variant 0.25 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619528 c.-363C>G upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619531 c.-360T>C upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619535 c.-356_-354delCAAinsGCG upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619543 c.-348C>G upstream_gene_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 619552 c.-339A>G upstream_gene_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 619555 c.-336C>G upstream_gene_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 619561 c.-330G>C upstream_gene_variant 0.71 kanamycin
capreomycin
amikacin
ccsA 619570 c.-321G>C upstream_gene_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 619574 c.-317G>A upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 619584 c.-307A>T upstream_gene_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619594 c.-297G>T upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619609 c.-282G>C upstream_gene_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>A upstream_gene_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 619645 c.-246G>C upstream_gene_variant 0.59 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>T upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619676 c.-215C>G upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620226 c.336G>A synonymous_variant 0.51 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620265 c.375C>G synonymous_variant 0.61 kanamycin
capreomycin
amikacin
ccsA 620268 c.378G>C synonymous_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>T synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620298 c.408G>C synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620310 c.420C>T synonymous_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.78 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>T synonymous_variant 0.79 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620389 c.499C>T synonymous_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.69 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620424 c.534G>C synonymous_variant 0.66 kanamycin
capreomycin
amikacin
ccsA 620433 c.543C>G synonymous_variant 0.65 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>G synonymous_variant 0.49 kanamycin
capreomycin
amikacin
ccsA 620461 p.Val191Ile missense_variant 0.47 kanamycin
capreomycin
amikacin
ccsA 620464 p.Ala192Ser missense_variant 0.48 kanamycin
capreomycin
amikacin
ccsA 620481 c.591T>G synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620482 p.Val198Leu missense_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620490 c.600A>C synonymous_variant 0.31 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620583 c.693G>C synonymous_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620586 c.696C>G synonymous_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620601 c.711C>T synonymous_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620607 c.717T>C synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620613 c.723C>G synonymous_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620622 c.732G>C synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>G synonymous_variant 0.48 kanamycin
capreomycin
amikacin
ccsA 620646 c.756G>A synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620659 c.769_771delCGCinsAGG synonymous_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620664 c.774C>T synonymous_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 620682 c.792G>A synonymous_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 620688 c.798G>C synonymous_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.71 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.71 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.66 kanamycin
capreomycin
amikacin
ccsA 620745 c.855G>C synonymous_variant 0.66 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>A synonymous_variant 0.66 kanamycin
capreomycin
amikacin
ccsA 620763 c.873G>A synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620769 c.879C>G synonymous_variant 0.64 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 620784 c.894C>G synonymous_variant 0.59 kanamycin
capreomycin
amikacin
ccsA 620790 c.900C>T synonymous_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 620796 c.906C>G synonymous_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620809 c.919C>T synonymous_variant 0.51 kanamycin
capreomycin
amikacin
ccsA 620823 c.933C>T synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620832 c.942C>T synonymous_variant 0.25 kanamycin
capreomycin
amikacin
Rv0565c 656179 p.Asp431Thr missense_variant 0.26 ethionamide
Rv0565c 656192 p.Asp427Asn missense_variant 0.34 ethionamide Uncertain significance
Rv0565c 656196 p.Leu425Arg missense_variant 0.35 ethionamide
Rv0565c 656219 p.His418Tyr missense_variant 0.43 ethionamide
Rv0565c 656220 c.1251A>C synonymous_variant 0.44 ethionamide
Rv0565c 656223 c.1248T>C synonymous_variant 0.43 ethionamide Not assoc w R - Interim
Rv0565c 656226 p.Ala415Ser missense_variant 0.41 ethionamide
Rv0565c 656238 p.Ala411Glu missense_variant 0.41 ethionamide
Rv0565c 656243 p.Leu410Met missense_variant 0.42 ethionamide
Rv0565c 656244 c.1227A>C synonymous_variant 0.42 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.43 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.41 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.4 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.42 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.46 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.47 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 0.42 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.35 ethionamide Not assoc w R - Interim
Rv0565c 656361 c.1110C>G synonymous_variant 0.35 ethionamide
Rv0565c 656364 c.1107T>C synonymous_variant 0.35 ethionamide
Rv0565c 656367 c.1101_1104delTCGGinsGC frameshift_variant&synonymous_variant 0.35 ethionamide Uncertain significance
Rv0565c 656371 p.Pro367His missense_variant 0.33 ethionamide
Rv0565c 656375 c.1095_1096insAA frameshift_variant 0.34 ethionamide Uncertain significance
Rv0565c 656383 p.Val363Asn missense_variant 0.35 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.41 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 0.41 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.42 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.45 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.47 ethionamide
Rv0565c 656448 p.Ile341Val missense_variant 0.41 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.4 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.4 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.42 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.42 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.37 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.37 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.4 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.39 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.4 ethionamide Not assoc w R - Interim
Rv0565c 656526 p.Glu315Asp missense_variant 0.41 ethionamide
Rv0565c 656535 c.936C>G synonymous_variant 0.38 ethionamide
Rv0565c 656539 p.Ser311Ala missense_variant 0.35 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 0.34 ethionamide
Rv0565c 656550 p.Asn307Glu missense_variant 0.33 ethionamide
Rv0565c 656924 p.Ile183Val missense_variant 0.35 ethionamide
Rv0565c 656936 p.Thr179Ala missense_variant 0.37 ethionamide
Rv0565c 656940 c.531C>T synonymous_variant 0.37 ethionamide Not assoc w R - Interim
Rv0565c 656946 c.525T>C synonymous_variant 0.38 ethionamide
Rv0565c 656952 c.519A>C synonymous_variant 0.39 ethionamide Not assoc w R - Interim
Rv0565c 656967 c.504T>C synonymous_variant 0.37 ethionamide
Rv0565c 656973 c.498A>G synonymous_variant 0.37 ethionamide
Rv0565c 656978 p.Ala165Thr missense_variant 0.37 ethionamide
Rv0565c 656982 p.Gly163Gln missense_variant 0.38 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 0.38 ethionamide
Rv0565c 656990 p.Lys161Glu missense_variant 0.38 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 0.38 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 0.45 ethionamide
Rv0565c 657056 p.Val139Leu missense_variant 0.33 ethionamide
Rv0565c 657060 c.411G>C synonymous_variant 0.31 ethionamide
Rv0565c 657065 p.Ser136Gly missense_variant 0.29 ethionamide
Rv0565c 657073 p.His133Leu missense_variant 0.25 ethionamide
Rv0565c 657081 p.Val130Glu missense_variant 0.76 ethionamide
Rv0565c 657114 c.357T>C synonymous_variant 0.28 ethionamide Not assoc w R - Interim
Rv0565c 657120 p.Ser117Ala missense_variant 0.28 ethionamide
Rv0565c 657123 c.348A>C synonymous_variant 0.28 ethionamide
Rv0565c 657138 p.Ala111Ser missense_variant 0.3 ethionamide
Rv0565c 657142 p.Arg110His missense_variant 0.67 ethionamide Uncertain significance
Rv0565c 657144 c.327T>G synonymous_variant 0.34 ethionamide
Rv0565c 657155 p.Asn106Asp missense_variant 0.37 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 0.36 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 0.4 ethionamide
Rv0565c 657187 p.His95Arg missense_variant 0.3 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 0.3 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.3 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.3 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 0.3 ethionamide Uncertain significance
Rv0565c 657201 c.270C>G synonymous_variant 0.3 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.41 ethionamide
Rv0565c 657231 p.Ile80Val missense_variant 0.47 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.51 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.56 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.55 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.54 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.54 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.64 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.58 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.57 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.58 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.59 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.59 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.57 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.56 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.54 ethionamide
Rv0565c 657372 c.99G>C synonymous_variant 0.5 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.49 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.47 ethionamide
Rv0565c 657399 c.72G>C synonymous_variant 0.41 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 0.4 ethionamide
Rv0565c 657405 p.Leu22Ile missense_variant 0.4 ethionamide
Rv0565c 657408 c.63A>C synonymous_variant 0.4 ethionamide
Rv0565c 657434 p.Val13Ile missense_variant 0.22 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.31 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.38 ethionamide
Rv0565c 657600 c.-132_-131delCA upstream_gene_variant 0.4 ethionamide
Rv0565c 657606 c.-136T>G upstream_gene_variant 0.39 ethionamide
Rv0565c 657607 c.-138_-137insCA upstream_gene_variant 0.39 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.41 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.42 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.51 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.54 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.6 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.69 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.65 ethionamide
hadA 731682 c.-248C>G upstream_gene_variant 0.47 isoniazid
hadA 731687 c.-243_-242insCACAGATCTTTT upstream_gene_variant 0.47 isoniazid
hadA 731693 c.-237C>A upstream_gene_variant 0.46 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.46 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 0.45 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.45 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.44 isoniazid
hadA 731717 c.-213T>G upstream_gene_variant 0.47 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.49 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.5 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.42 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.3 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.29 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.2 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.26 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.28 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.28 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.29 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.42 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.44 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.45 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.47 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.5 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.52 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.54 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.56 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.57 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 0.39 rifampicin Uncertain significance
nusG 734093 c.-161A>C upstream_gene_variant 0.39 rifampicin
nusG 734096 c.-158C>T upstream_gene_variant 0.39 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.39 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.38 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.38 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.4 rifampicin Uncertain significance
nusG 734123 c.-131C>G upstream_gene_variant 0.38 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 0.38 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.38 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.41 rifampicin
nusG 734144 c.-110G>C upstream_gene_variant 0.45 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.45 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 0.52 rifampicin
nusG 734175 c.-79_-77delGGTinsCTG upstream_gene_variant 0.52 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 0.51 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 0.52 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.51 rifampicin Uncertain significance
nusG 734205 c.-49A>C upstream_gene_variant 0.51 rifampicin
nusG 734223 c.-30_-28delGCT upstream_gene_variant 0.32 rifampicin
nusG 734249 c.-5_-4delAAinsC upstream_gene_variant 0.3 rifampicin
nusG 734261 p.Thr3Ser missense_variant 0.31 rifampicin
nusG 734275 p.Thr8Pro missense_variant 0.22 rifampicin
nusG 734340 c.87T>C synonymous_variant 0.22 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.29 rifampicin
nusG 734360 p.Ala36Val missense_variant 0.38 rifampicin Uncertain significance
nusG 734370 c.117A>G synonymous_variant 0.46 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.52 rifampicin
nusG 734407 p.Val52Ile missense_variant 0.68 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.72 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.72 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.76 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.77 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.77 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.79 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.81 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.77 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.77 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.77 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.78 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.79 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.78 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.73 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.71 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.7 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.71 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.71 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.68 rifampicin
nusG 734658 c.405A>G synonymous_variant 0.65 rifampicin Not assoc w R
nusG 734661 c.408A>C synonymous_variant 0.63 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.63 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.61 rifampicin
nusG 734676 c.423G>C synonymous_variant 0.59 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
nusG 734680 p.Ala143Thr missense_variant 0.57 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.67 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.65 rifampicin
nusG 734715 c.462G>C synonymous_variant 0.59 rifampicin
nusG 734718 c.465G>C synonymous_variant 0.58 rifampicin
nusG 734719 p.Ser156Ala missense_variant 0.58 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.53 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.55 rifampicin
nusG 734742 c.489T>G synonymous_variant 0.44 rifampicin
nusG 734748 c.495C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
nusG 734750 p.Ser166Thr missense_variant 0.3 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.3 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.29 rifampicin
nusG 734758 p.Ala169Thr missense_variant 0.3 rifampicin
nusG 734772 c.519G>C synonymous_variant 0.42 rifampicin
nusG 734775 c.522C>G synonymous_variant 0.43 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.45 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.44 rifampicin
nusG 734787 c.534T>C synonymous_variant 0.44 rifampicin
nusG 734792 p.Val180Ala missense_variant 0.44 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.44 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.51 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.56 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>C synonymous_variant 0.44 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.4 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.39 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.38 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.38 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.37 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.37 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.31 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.3 rifampicin
nusG 734931 c.678A>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734937 c.684G>C synonymous_variant 0.29 rifampicin
nusG 734940 c.687G>A synonymous_variant 0.24 rifampicin
nusG 734941 c.688C>T synonymous_variant 0.24 rifampicin
mmaA3 738337 c.-188T>C upstream_gene_variant 0.42 isoniazid
mmaA3 738346 c.-198_-197delCTinsGC upstream_gene_variant 0.4 isoniazid
mmaA3 738348 c.-199G>C upstream_gene_variant 0.39 isoniazid
rpoB 759606 c.-201T>C upstream_gene_variant 0.3 rifampicin
rpoB 759629 c.-178T>C upstream_gene_variant 0.32 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.31 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoB 759656 c.-151delAinsCCCTAC upstream_gene_variant 0.33 rifampicin
rpoB 759667 c.-140C>T upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoB 759670 c.-137C>T upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.31 rifampicin
rpoB 759672 c.-135G>C upstream_gene_variant 0.31 rifampicin
rpoB 759683 c.-124T>C upstream_gene_variant 0.3 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 0.28 rifampicin
rpoB 760060 p.Tyr85Leu missense_variant 0.3 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.31 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.33 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.56 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.63 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.63 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.77 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.76 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.77 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.74 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.73 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.71 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.71 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.69 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.71 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.71 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760520 c.714C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.75 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.76 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.76 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.76 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760637 c.831G>C synonymous_variant 0.72 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.7 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.69 rifampicin
rpoB 760718 c.912C>T synonymous_variant 0.7 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.71 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.69 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.68 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.67 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.67 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.67 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.68 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.71 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.7 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.7 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.68 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.69 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.7 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.7 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.75 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.77 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.77 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.76 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.79 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.75 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.77 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>T synonymous_variant 0.74 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.74 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.74 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.74 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.73 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.73 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.7 rifampicin
rpoB 761372 c.1566C>T synonymous_variant 0.68 rifampicin
rpoB 761373 p.Val523His missense_variant 0.68 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.69 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.67 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.6 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.59 rifampicin
rpoB 761439 p.Asp545Lys missense_variant 0.58 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.58 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.57 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.57 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.56 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.6 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.63 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.64 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.7 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.72 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.73 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.75 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.71 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.68 rifampicin
rpoB 761720 c.1914C>G synonymous_variant 0.66 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.65 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.64 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.69 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.69 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.68 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.67 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.69 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.7 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.71 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.69 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.67 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.66 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.67 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.68 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.73 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.75 rifampicin
rpoB 761906 c.2100C>A synonymous_variant 0.73 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.72 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.73 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.74 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.74 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.78 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.81 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.81 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.81 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.8 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762170 c.2364C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.8 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.78 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.78 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.71 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.69 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.68 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.67 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.63 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.63 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.64 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762410 c.2604T>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762413 c.2607G>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.6 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.68 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.64 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.59 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.54 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.54 rifampicin Uncertain significance
rpoC 762521 c.-849C>T upstream_gene_variant 0.53 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.48 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.47 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.46 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.46 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.25 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 0.33 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 0.33 rifampicin
rpoC 762743 c.-627G>T upstream_gene_variant 0.32 rifampicin
rpoB 762744 p.Gln980Ala missense_variant 0.32 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.34 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 0.36 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.47 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.46 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.53 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.55 rifampicin Uncertain significance
rpoB 762810 p.Ala1002Ser missense_variant 0.6 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.58 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.78 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.82 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.62 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.64 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.61 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.59 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.58 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.59 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.55 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.52 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.52 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.28 rifampicin
rpoC 763352 c.-18T>A upstream_gene_variant 0.25 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 0.53 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.55 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.61 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.67 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.75 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.74 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.74 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.73 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.73 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.68 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.66 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.59 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.61 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.61 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.6 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.57 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.55 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.55 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.54 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.54 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.54 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.53 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.47 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.45 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.45 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.45 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.48 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.45 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.43 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.45 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.43 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.39 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.4 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.39 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.39 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.51 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.52 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.57 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.67 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.67 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.66 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.67 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.69 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.63 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.64 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.65 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.64 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.65 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.66 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.69 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.71 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.7 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.7 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.71 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.63 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.63 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.67 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.65 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.64 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.61 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.6 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.49 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.44 rifampicin
rpoC 765121 c.1752G>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765292 c.1923G>C synonymous_variant 0.5 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 0.52 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.53 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.65 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.65 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 0.69 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.77 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.78 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.77 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>A synonymous_variant 0.77 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.75 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.74 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.74 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.74 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.72 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.68 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.68 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.67 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.66 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.66 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.7 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.71 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.71 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.7 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.71 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.76 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.77 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.77 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.77 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.77 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.77 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.76 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.75 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.68 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.67 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.56 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.51 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 766174 p.Asn935Lys missense_variant 0.44 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.38 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.28 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 766192 c.2823T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 766193 p.Gln942Glu missense_variant 0.27 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 0.28 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 0.28 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 0.28 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.28 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.28 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.32 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.36 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.47 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.57 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.64 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.64 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.68 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.69 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.72 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.72 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.72 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.74 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.76 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.76 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.78 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.79 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.77 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.72 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.7 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.72 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.72 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.71 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.71 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.71 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.72 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.68 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.62 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.61 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.61 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.61 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.65 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.69 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.66 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.64 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.64 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.7 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.73 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.74 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.74 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.76 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.75 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.77 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.76 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.69 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.69 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.7 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.69 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.68 rifampicin
rpoC 767146 c.3777G>A synonymous_variant 0.67 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.7 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.67 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.54 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.52 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.53 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.53 rifampicin
rpoC 767288 c.3919C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775901 c.2580G>A synonymous_variant 0.55 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.6 bedaquiline
clofazimine
mmpL5 775913 c.2568C>G synonymous_variant 0.61 bedaquiline
clofazimine
mmpL5 775916 c.2565T>C synonymous_variant 0.6 bedaquiline
clofazimine
mmpL5 775921 c.2560C>T synonymous_variant 0.53 bedaquiline
clofazimine
mmpL5 775937 p.Ala848Ser missense_variant 0.46 bedaquiline
clofazimine
mmpL5 775943 c.2538C>G synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 775946 c.2535C>G synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 775955 p.Ile842Met missense_variant 0.26 bedaquiline
clofazimine
mmpL5 775961 c.2520C>G synonymous_variant 0.46 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.32 bedaquiline
clofazimine
mmpL5 775973 c.2506_2508delTTGinsCTC synonymous_variant 0.31 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.61 bedaquiline
clofazimine
mmpL5 775990 c.2491C>T synonymous_variant 0.3 bedaquiline
clofazimine
mmpL5 775991 p.Glu830Lys missense_variant 0.31 bedaquiline
clofazimine
mmpL5 775994 p.Ile829Leu missense_variant 0.3 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.31 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.32 bedaquiline
clofazimine
mmpL5 776005 p.Ile826Leu missense_variant 0.32 bedaquiline
clofazimine
mmpL5 776008 p.His825Tyr missense_variant 0.3 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.61 bedaquiline
clofazimine
mmpL5 776015 p.Ile822Leu missense_variant 0.3 bedaquiline
clofazimine
mmpL5 776018 c.2463G>C synonymous_variant 0.3 bedaquiline
clofazimine
mmpL5 776024 c.2457G>C synonymous_variant 0.3 bedaquiline
clofazimine
mmpL5 776027 c.2454G>C synonymous_variant 0.3 bedaquiline
clofazimine
mmpL5 776030 c.2451G>A synonymous_variant 0.59 bedaquiline
clofazimine
mmpL5 776036 c.2445G>C synonymous_variant 0.23 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 776056 p.Val809Leu missense_variant 0.4 bedaquiline
clofazimine
mmpL5 776060 c.2421C>G synonymous_variant 0.39 bedaquiline
clofazimine
mmpL5 776072 c.2409C>G synonymous_variant 0.34 bedaquiline
clofazimine
mmpL5 776076 p.Ala802Val missense_variant 0.3 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 777095 c.1386T>C synonymous_variant 0.29 bedaquiline
clofazimine
mmpL5 777101 c.1380C>G synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 777110 c.1371T>G synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 777115 p.Met456Leu missense_variant 0.39 bedaquiline
clofazimine
mmpL5 777116 c.1365C>T synonymous_variant 0.39 bedaquiline
clofazimine
mmpL5 777133 p.Val450Ile missense_variant 0.45 bedaquiline
clofazimine
mmpL5 777158 c.1323C>G synonymous_variant 0.46 bedaquiline
clofazimine
mmpL5 777164 c.1317C>G synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 777170 c.1311T>C synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 777176 p.Glu435Asp missense_variant 0.45 bedaquiline
clofazimine
mmpL5 777191 c.1290C>G synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 777194 c.1287A>G synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 777206 c.1275A>G synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 777212 p.Ala423Thr missense_variant 0.5 bedaquiline
clofazimine
mmpL5 777215 c.1266C>G synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 777218 c.1263G>A synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 777254 c.1227G>C synonymous_variant 0.3 bedaquiline
clofazimine
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.44 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.53 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.57 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.57 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.66 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.66 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.76 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.76 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.75 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.75 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.73 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.69 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.69 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.69 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.71 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.72 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.73 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.7 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.69 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.71 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.7 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.69 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.7 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.71 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.72 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.74 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.72 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.71 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.72 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.72 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.52 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.6 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.62 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.64 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.67 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.68 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.7 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.71 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.72 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.72 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.71 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.7 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.69 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.72 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.72 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.72 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.71 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.69 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.67 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.67 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.68 linezolid
rplC 800814 c.6A>G synonymous_variant 0.7 linezolid
rplC 800817 c.9A>T synonymous_variant 0.69 linezolid
rplC 800844 c.36T>C synonymous_variant 0.72 linezolid
rplC 800865 c.57A>G synonymous_variant 0.64 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.63 linezolid
rplC 800874 c.66A>G synonymous_variant 0.63 linezolid
rplC 800875 p.Val23Ile missense_variant 0.61 linezolid
rplC 800880 c.72A>G synonymous_variant 0.61 linezolid
rplC 800889 c.81C>G synonymous_variant 0.6 linezolid
rplC 800892 c.84G>C synonymous_variant 0.59 linezolid
rplC 800907 c.99C>G synonymous_variant 0.58 linezolid
rplC 800916 c.108A>G synonymous_variant 0.56 linezolid
rplC 800934 c.126C>G synonymous_variant 0.5 linezolid
rplC 800937 c.129A>G synonymous_variant 0.49 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.49 linezolid
rplC 800946 c.138T>C synonymous_variant 0.48 linezolid
rplC 800949 c.141T>C synonymous_variant 0.49 linezolid
rplC 800967 c.159C>G synonymous_variant 0.41 linezolid
rplC 800970 c.162T>C synonymous_variant 0.4 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.25 linezolid
rplC 801127 p.Ala107Thr missense_variant 0.25 linezolid
rplC 801156 c.348T>A synonymous_variant 0.27 linezolid
rplC 801168 c.360C>G synonymous_variant 0.29 linezolid
rplC 801171 c.363A>G synonymous_variant 0.31 linezolid
rplC 801174 c.366T>C synonymous_variant 0.33 linezolid
rplC 801180 c.372C>G synonymous_variant 0.4 linezolid
rplC 801195 c.387G>C synonymous_variant 0.46 linezolid
rplC 801207 c.399C>T synonymous_variant 0.5 linezolid
rplC 801246 c.438C>T synonymous_variant 0.65 linezolid
rplC 801249 c.441T>C synonymous_variant 0.63 linezolid
rplC 801255 c.447C>T synonymous_variant 0.65 linezolid
rplC 801264 c.456C>T synonymous_variant 0.64 linezolid
rplC 801267 c.459A>T synonymous_variant 0.62 linezolid
rplC 801270 c.462T>C synonymous_variant 0.61 linezolid
rplC 801276 c.468G>C synonymous_variant 0.61 linezolid
rplC 801279 c.471G>C synonymous_variant 0.6 linezolid
rplC 801282 c.474G>C synonymous_variant 0.61 linezolid
rplC 801285 c.477G>C synonymous_variant 0.6 linezolid
rplC 801300 c.492C>G synonymous_variant 0.66 linezolid
rplC 801309 c.501C>G synonymous_variant 0.66 linezolid
rplC 801312 c.504G>C synonymous_variant 0.67 linezolid
rplC 801321 c.513C>T synonymous_variant 0.65 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.66 linezolid
rplC 801339 c.531T>C synonymous_variant 0.64 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.64 linezolid
rplC 801348 c.540T>G synonymous_variant 0.65 linezolid
rplC 801357 c.549T>C synonymous_variant 0.62 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.61 linezolid
rplC 801402 c.594T>C synonymous_variant 0.6 linezolid
rplC 801405 c.597T>C synonymous_variant 0.62 linezolid
rplC 801423 c.615G>C synonymous_variant 0.69 linezolid
rplC 801426 c.618C>G synonymous_variant 0.68 linezolid
rplC 801427 p.Met207Val missense_variant 0.69 linezolid
rplC 801438 c.630T>C synonymous_variant 0.7 linezolid
rplC 801442 p.Ile212Val missense_variant 0.7 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
fbiC 1303455 c.525C>G synonymous_variant 0.35 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303476 c.546G>C synonymous_variant 0.4 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303480 p.Gln184Glu missense_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303489 c.559C>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303497 c.567G>A synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303501 c.571C>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303521 c.591C>T synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303530 c.600G>A synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1303539 c.609G>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303641 c.711C>T synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1303650 c.720G>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1303654 c.724C>T synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303659 c.729T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303661 p.Val244Ala missense_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303663 c.733C>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303671 c.741C>T synonymous_variant 0.48 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1303674 c.744C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303680 c.750G>A synonymous_variant 0.5 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303681 c.751T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303728 c.798G>A synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 0.58 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303761 c.831T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1303797 c.867A>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303914 c.984C>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>T synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1303944 c.1014G>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>G synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303953 p.Asp341Glu missense_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303954 p.Glu342Gln missense_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1303971 c.1041T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>A synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1304004 c.1074A>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304034 c.1104A>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304040 c.1110C>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304046 c.1116C>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304050 c.1120T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304058 c.1128G>A synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304059 c.1129C>T synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304085 c.1155C>T synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304091 p.Asp387Glu missense_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304097 c.1167G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304132 p.Ala401Gly missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304142 c.1212G>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304161 p.Arg411Ser missense_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304169 c.1239T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304174 p.Val415Ala missense_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304187 c.1257T>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304208 c.1278C>T synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304223 c.1293G>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304226 c.1296C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304227 p.Met433Leu missense_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304443 p.Ala505Thr missense_variant 0.98 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiC 1304499 c.1569T>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304511 c.1581C>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304535 c.1605G>A synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304545 p.Val539Thr missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304553 c.1623C>T synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304711 p.Ala594Glu missense_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.63 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.75 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304883 p.Glu651Asp missense_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1304943 c.2013C>A synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1305012 c.2082G>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1305030 c.2100G>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305045 c.2115A>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305063 c.2133G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305066 c.2136T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1305069 c.2139G>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1305075 c.2145T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1305078 c.2148A>G synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1305081 c.2151G>C synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1305090 c.2160C>G synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1305092 p.Ala721Gly missense_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1305114 c.2184T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1305117 c.2187T>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 0.45 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305150 c.2220C>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1305154 c.2224_2226delTTGinsCTA synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1305173 p.Asn748Ser missense_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1305177 c.2247A>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1305181 c.2251T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1305186 c.2256C>T synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1305195 c.2265T>C synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1305201 c.2271G>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1305204 c.2274C>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1305210 c.2280G>A synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1305215 p.Ser762Thr missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1305219 c.2289T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1305231 c.2301C>A synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305234 c.2304G>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1305240 c.2310T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1305243 c.2313T>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305244 c.2314T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1305252 c.2322G>A synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1305273 c.2343C>T synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1305276 c.2346G>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1305279 p.His783Gln missense_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1305282 c.2352T>C synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fbiC 1305297 c.2367G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1305300 c.2370A>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1305303 c.2373T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1305306 c.2376A>T synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1305309 c.2379G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1305310 p.Arg794Glu missense_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1305318 c.2388C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1305331 p.Glu801Asn missense_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305369 c.2439G>A synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1305372 c.2442G>A synonymous_variant 0.45 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305384 c.2454G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1305396 c.2466C>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1305405 c.2475A>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine Not assoc w R - Interim
sigE 1364802 c.390C>A synonymous_variant 0.49 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.51 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.58 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.58 pyrazinamide
sigE 1364839 c.427_429delTTGinsCTC synonymous_variant 0.58 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.58 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.57 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 0.57 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.54 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.53 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.46 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.43 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.43 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.45 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.44 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 0.36 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.36 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.25 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
sigE 1365006 c.594T>C synonymous_variant 0.27 pyrazinamide
sigE 1365009 c.597C>G synonymous_variant 0.27 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.27 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.29 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.29 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.29 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.29 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.28 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.28 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.25 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.24 pyrazinamide
atpE 1460831 c.-214T>C upstream_gene_variant 0.25 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.27 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.27 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.27 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.28 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.29 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.28 bedaquiline
atpE 1461113 c.69C>T synonymous_variant 0.24 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.31 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.35 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 0.34 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.34 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.33 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.33 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.35 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.36 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.35 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.3 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.29 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.29 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.29 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.29 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.49 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.49 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.49 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.49 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.48 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.55 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.55 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473941 n.284T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1473996 n.339C>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.69 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474952 n.1295A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.47 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
inhA 1673487 c.-715T>C upstream_gene_variant 0.24 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673490 c.-712A>G upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673523 c.-679G>T upstream_gene_variant 0.51 isoniazid
ethionamide
inhA 1673535 c.-667A>G upstream_gene_variant 0.58 isoniazid
ethionamide
inhA 1673547 c.-655T>C upstream_gene_variant 0.62 isoniazid
ethionamide
inhA 1673568 c.-634C>G upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1673574 c.-628C>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673580 c.-622T>G upstream_gene_variant 0.72 isoniazid Uncertain significance
ethionamide
inhA 1673589 c.-613A>G upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673595 c.-607A>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673596 c.-606A>G upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673602 c.-600C>T upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673607 c.-595T>C upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673615 c.-587_-586delAAinsTG upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673619 c.-583T>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673633 c.-569G>A upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1673637 c.-565C>G upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673641 c.-561G>A upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673646 c.-556T>C upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673657 c.-545C>A upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.74 isoniazid
ethionamide
inhA 1673679 c.-523T>G upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673685 c.-517C>T upstream_gene_variant 0.71 isoniazid
ethionamide
inhA 1673710 c.-492C>A upstream_gene_variant 0.58 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsAA upstream_gene_variant 0.55 isoniazid
ethionamide
inhA 1673733 c.-469G>C upstream_gene_variant 0.47 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.46 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673758 c.-444A>G upstream_gene_variant 0.54 isoniazid
ethionamide
inhA 1673797 c.-405_-403delGCTinsACC upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673805 c.-397G>C upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673808 c.-394A>C upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673809 c.-393T>G upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673829 c.-373C>A upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1673841 c.-361A>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673844 c.-358G>C upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673849 c.-353T>A upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673853 c.-349A>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673856 c.-346T>C upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673890 c.-312G>T upstream_gene_variant 0.42 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673916 c.-286A>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673940 c.-262C>T upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.47 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.54 isoniazid
ethionamide
inhA 1673985 c.-217C>G upstream_gene_variant 0.64 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1674015 c.-187C>T upstream_gene_variant 0.67 isoniazid Uncertain significance
ethionamide
inhA 1674018 c.-184G>C upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674021 c.-181G>C upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 0.68 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674037 c.-165_-164delCAinsGC upstream_gene_variant 0.66 isoniazid
ethionamide
inhA 1674042 c.-160G>C upstream_gene_variant 0.66 isoniazid Uncertain significance
ethionamide
inhA 1674049 c.-153_-151delCAAinsGAT upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 0.66 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674063 c.-139G>C upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 0.68 isoniazid
ethionamide
inhA 1674114 c.-88T>A upstream_gene_variant 0.56 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1674126 c.-76G>C upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1674136 c.-66T>G upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1674471 c.270G>C synonymous_variant 0.32 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.4 isoniazid
ethionamide
inhA 1674504 c.303C>G synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.6 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.58 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.58 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.58 isoniazid
ethionamide
inhA 1674552 c.351C>G synonymous_variant 0.58 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 0.58 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.61 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.69 isoniazid
ethionamide
inhA 1674601 p.Leu134Thr missense_variant 0.69 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674630 c.429C>G synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674672 c.471C>G synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674723 c.522C>T synonymous_variant 0.69 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674738 c.537C>G synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674741 c.540C>T synonymous_variant 0.66 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674746 p.Tyr182Phe missense_variant 0.66 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 0.65 isoniazid
ethionamide
inhA 1674753 c.552G>C synonymous_variant 0.66 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.66 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.66 isoniazid
ethionamide
inhA 1674828 c.627G>A synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.65 isoniazid
ethionamide
inhA 1674864 c.663C>T synonymous_variant 0.63 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.58 isoniazid
ethionamide
inhA 1674900 c.699G>A synonymous_variant 0.57 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.58 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.59 isoniazid
ethionamide
inhA 1674909 c.708G>A synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 0.55 isoniazid
ethionamide
inhA 1674960 c.759C>G synonymous_variant 0.49 isoniazid
ethionamide
inhA 1674966 c.765T>G synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674967 p.Asp256Thr missense_variant 0.43 isoniazid
ethionamide
inhA 1674987 c.786C>T synonymous_variant 0.32 isoniazid
ethionamide
rpsA 1833515 c.-27_-24delCAACinsAAA upstream_gene_variant 0.34 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.49 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.61 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.68 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.71 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.78 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.77 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.81 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.8 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.8 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.8 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.79 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.8 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.78 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.78 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.78 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.78 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.77 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.77 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.77 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.77 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.76 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.78 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.77 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.75 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.75 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.74 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.67 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.67 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.68 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.68 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.58 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.57 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.57 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.58 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.69 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.66 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.65 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 0.75 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.78 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834510 c.969C>T synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
rpsA 1834513 c.972C>G synonymous_variant 0.76 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.68 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.69 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.64 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.63 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.58 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.55 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.54 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.53 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.52 pyrazinamide
rpsA 1834849 c.1308C>G synonymous_variant 0.25 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.64 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.65 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.68 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.68 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.7 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.68 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.68 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.64 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.61 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.6 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.59 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.55 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 0.53 linezolid
tsnR 1853484 c.-122_-120delAGCinsGCG upstream_gene_variant 0.53 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.55 linezolid
tsnR 1853498 c.-108G>C upstream_gene_variant 0.55 linezolid
tsnR 1853517 c.-89G>A upstream_gene_variant 0.5 linezolid
tsnR 1853525 c.-81G>C upstream_gene_variant 0.42 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 0.41 linezolid
tsnR 1853540 c.-66A>G upstream_gene_variant 0.34 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917908 c.-32C>G upstream_gene_variant 0.35 capreomycin
tlyA 1917929 c.-11T>C upstream_gene_variant 0.35 capreomycin
tlyA 1917937 c.-3_-2insC upstream_gene_variant 0.36 capreomycin
tlyA 1917940 p.Val1Met missense_variant 0.35 capreomycin
tlyA 1917943 p.Ala2Ser missense_variant 0.35 capreomycin
tlyA 1917951 c.12T>C synonymous_variant 0.38 capreomycin
tlyA 1917963 c.24C>T synonymous_variant 0.4 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.4 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.43 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.46 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.47 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>G synonymous_variant 0.49 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.51 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.56 capreomycin
tlyA 1918048 p.Leu37Met missense_variant 0.53 capreomycin
tlyA 1918053 c.114G>C synonymous_variant 0.49 capreomycin
tlyA 1918057 p.Val40Arg missense_variant 0.44 capreomycin
tlyA 1918065 c.126G>C synonymous_variant 0.44 capreomycin
tlyA 1918067 p.Ala43Gly missense_variant 0.45 capreomycin
tlyA 1918077 c.138G>C synonymous_variant 0.44 capreomycin
tlyA 1918078 p.Ser47Ala missense_variant 0.44 capreomycin
tlyA 1918082 p.Asp48Val missense_variant 0.42 capreomycin
tlyA 1918087 p.Thr50Ala missense_variant 0.42 capreomycin
tlyA 1918092 c.153G>C synonymous_variant 0.43 capreomycin
tlyA 1918103 p.Val55Ala missense_variant 0.43 capreomycin
tlyA 1918111 p.Ser58Gly missense_variant 0.42 capreomycin
tlyA 1918121 p.Ala61Gly missense_variant 0.47 capreomycin
tlyA 1918128 c.189A>C synonymous_variant 0.48 capreomycin
tlyA 1918137 c.198A>C synonymous_variant 0.42 capreomycin
tlyA 1918149 c.210A>C synonymous_variant 0.36 capreomycin
tlyA 1918150 p.Val71Ile missense_variant 0.33 capreomycin
tlyA 1918155 c.216T>C synonymous_variant 0.37 capreomycin
tlyA 1918164 p.Glu75Asp missense_variant 0.34 capreomycin
tlyA 1918172 p.Ala78Gly missense_variant 0.28 capreomycin
tlyA 1918177 p.Ala80Ser missense_variant 0.28 capreomycin
tlyA 1918191 c.252G>C synonymous_variant 0.38 capreomycin
tlyA 1918197 c.258T>C synonymous_variant 0.4 capreomycin
tlyA 1918206 c.267G>C synonymous_variant 0.45 capreomycin
tlyA 1918212 c.273A>G synonymous_variant 0.46 capreomycin
tlyA 1918218 c.279C>G synonymous_variant 0.46 capreomycin
tlyA 1918221 c.282T>C synonymous_variant 0.46 capreomycin
tlyA 1918224 c.285G>C synonymous_variant 0.48 capreomycin
tlyA 1918236 c.297A>C synonymous_variant 0.52 capreomycin
tlyA 1918248 c.309T>C synonymous_variant 0.49 capreomycin
tlyA 1918258 p.His107Glu missense_variant 0.44 capreomycin
tlyA 1918271 p.Ala111Val missense_variant 0.42 capreomycin
tlyA 1918275 c.336T>C synonymous_variant 0.44 capreomycin
tlyA 1918278 c.339C>G synonymous_variant 0.46 capreomycin
tlyA 1918310 p.Asn124Ser missense_variant 0.62 capreomycin
tlyA 1918315 p.Pro126Ala missense_variant 0.63 capreomycin
tlyA 1918323 c.384G>C synonymous_variant 0.63 capreomycin
tlyA 1918326 c.387G>C synonymous_variant 0.62 capreomycin
tlyA 1918330 p.Leu131Val missense_variant 0.63 capreomycin
tlyA 1918346 p.Ala136Val missense_variant 0.56 capreomycin
tlyA 1918352 p.Gly138Asp missense_variant 0.55 capreomycin
tlyA 1918356 c.417C>G synonymous_variant 0.55 capreomycin
tlyA 1918359 c.420A>G synonymous_variant 0.56 capreomycin
tlyA 1918362 c.423G>C synonymous_variant 0.57 capreomycin
tlyA 1918377 c.438T>G synonymous_variant 0.52 capreomycin
tlyA 1918379 p.Arg147Pro missense_variant 0.53 capreomycin
tlyA 1918382 p.Val148Ala missense_variant 0.51 capreomycin
tlyA 1918389 c.450G>C synonymous_variant 0.51 capreomycin
tlyA 1918392 c.453A>C synonymous_variant 0.5 capreomycin
tlyA 1918422 c.483T>C synonymous_variant 0.44 capreomycin
tlyA 1918425 c.486C>A synonymous_variant 0.4 capreomycin
tlyA 1918434 c.495C>G synonymous_variant 0.37 capreomycin
tlyA 1918442 p.Val168Ala missense_variant 0.31 capreomycin
bacA 2063229 c.1500G>A synonymous_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063265 p.Gly488Asp missense_variant 0.22 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063283 c.1446G>A synonymous_variant 0.22 kanamycin
capreomycin
streptomycin Not assoc w R - Interim
amikacin
bacA 2064858 c.-130T>C upstream_gene_variant 0.21 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064861 c.-133A>G upstream_gene_variant 0.23 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064870 c.-142A>G upstream_gene_variant 0.27 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064873 c.-145A>T upstream_gene_variant 0.31 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064882 c.-154C>G upstream_gene_variant 0.39 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064892 c.-164A>G upstream_gene_variant 0.44 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064897 c.-169C>G upstream_gene_variant 0.46 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064903 c.-175G>A upstream_gene_variant 0.49 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064912 c.-184A>G upstream_gene_variant 0.53 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064915 c.-187G>C upstream_gene_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064933 c.-205A>G upstream_gene_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064942 c.-214G>A upstream_gene_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.65 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.66 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.68 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.7 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101783 c.1260T>A synonymous_variant 0.24 isoniazid
delamanid
ethionamide
ndh 2101804 c.1239T>G synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2101808 p.Thr412Ser missense_variant 0.41 isoniazid
delamanid
ethionamide
ndh 2101830 p.Ile405Val missense_variant 0.47 isoniazid
delamanid
ethionamide
ndh 2101837 p.Ala402Val missense_variant 0.48 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101858 p.LeuIle394PheAla missense_variant 0.45 isoniazid
delamanid
ethionamide
ndh 2101872 p.Ile391Phe missense_variant 0.45 isoniazid
delamanid
ethionamide
ndh 2101873 p.Phe390Leu missense_variant 0.45 isoniazid
delamanid
ethionamide
ndh 2101885 c.1158G>A synonymous_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2101888 c.1155T>C synonymous_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2101891 c.1152C>G synonymous_variant 0.43 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.49 isoniazid
delamanid
ethionamide
ndh 2101912 c.1131G>C synonymous_variant 0.56 isoniazid
delamanid
ethionamide
ndh 2101920 c.1123A>C synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>G synonymous_variant 0.57 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>G synonymous_variant 0.56 isoniazid
delamanid
ethionamide
ndh 2101960 c.1083A>G synonymous_variant 0.41 isoniazid
delamanid
ethionamide
ndh 2101963 c.1080G>A synonymous_variant 0.36 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101966 c.1077T>G synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2101972 c.1071G>C synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2101988 p.Ala352Asp missense_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2101990 c.1053G>C synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2101993 c.1050A>G synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102011 c.1032C>G synonymous_variant 0.36 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102014 c.1029C>G synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102020 c.1023A>G synonymous_variant 0.34 isoniazid
delamanid
ethionamide
ndh 2102023 c.1020G>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102026 c.1017G>C synonymous_variant 0.34 isoniazid
delamanid
ethionamide
ndh 2102038 c.1005C>A synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102044 c.999G>C synonymous_variant 0.22 isoniazid
delamanid
ethionamide
ndh 2102302 c.741G>C synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102305 c.738T>C synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102314 c.729C>T synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102328 p.Leu239Met missense_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2102332 p.Gln237Glu missense_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2102342 p.Ala234Asp missense_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102366 p.Ala226Glu missense_variant 0.24 isoniazid Uncertain significance
delamanid
ethionamide
ndh 2102373 p.Met224Leu missense_variant 0.24 isoniazid
delamanid
ethionamide
ndh 2102695 c.348C>T synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102700 c.343C>T synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102710 c.333C>T synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2102718 p.Gln109Glu missense_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2102728 c.315T>C synonymous_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2102737 p.Glu102Asp missense_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2102750 p.Cys98Phe missense_variant 0.31 isoniazid
delamanid
ethionamide
ndh 2102754 p.Gln97Lys missense_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2102755 c.288G>C synonymous_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2102758 c.285C>G synonymous_variant 0.34 isoniazid
delamanid
ethionamide
ndh 2102773 c.270C>G synonymous_variant 0.47 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102781 p.Asn88Asp missense_variant 0.44 isoniazid Uncertain significance
delamanid
ethionamide
ndh 2102785 c.256_258delTTGinsCTC synonymous_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2102790 c.253C>T synonymous_variant 0.41 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102791 c.252A>G synonymous_variant 0.4 isoniazid
delamanid
ethionamide
ndh 2102800 c.243T>C synonymous_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2102810 p.Lys78Arg missense_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2102812 c.231T>C synonymous_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2102830 c.213G>C synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102836 c.207T>C synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102842 p.Glu67Asp missense_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102845 c.198A>C synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102848 c.195G>A synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102854 p.Ile63Val missense_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2102857 c.186T>C synonymous_variant 0.33 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 0.33 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102863 c.180C>G synonymous_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2102866 c.177C>G synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102872 c.171A>G synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102893 c.150G>C synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102899 c.144T>C synonymous_variant 0.34 isoniazid
delamanid
ethionamide
ndh 2102902 c.141C>G synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102911 c.132G>C synonymous_variant 0.26 isoniazid
delamanid
ethionamide
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155626 c.486G>C synonymous_variant 0.24 isoniazid
katG 2155632 c.480A>C synonymous_variant 0.27 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.33 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.4 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 0.48 isoniazid
katG 2155677 c.435C>G synonymous_variant 0.51 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.53 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.51 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.52 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.56 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.56 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.56 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.55 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.53 isoniazid
katG 2155743 c.369G>C synonymous_variant 0.53 isoniazid
katG 2155782 c.330C>G synonymous_variant 0.38 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.34 isoniazid
katG 2155794 p.Ala106Ser missense_variant 0.26 isoniazid
katG 2155806 c.306T>C synonymous_variant 0.24 isoniazid
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
PPE35 2168679 p.Ser645Ile missense_variant 0.98 pyrazinamide Uncertain significance
PPE35 2170819 c.-207C>A upstream_gene_variant 0.99 pyrazinamide
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
pncA 2289880 c.-639T>C upstream_gene_variant 0.25 pyrazinamide
pncA 2289883 c.-642C>G upstream_gene_variant 0.27 pyrazinamide
pncA 2289892 c.-651C>G upstream_gene_variant 0.32 pyrazinamide
pncA 2289895 c.-654C>G upstream_gene_variant 0.32 pyrazinamide
pncA 2289906 c.-665T>C upstream_gene_variant 0.34 pyrazinamide
pncA 2289907 c.-666A>C upstream_gene_variant 0.34 pyrazinamide
pncA 2289913 c.-672T>C upstream_gene_variant 0.43 pyrazinamide
pncA 2289925 c.-684T>C upstream_gene_variant 0.49 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 0.49 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 0.51 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 0.51 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 0.52 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.54 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.53 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.52 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.54 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.54 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.54 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.55 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCAC upstream_gene_variant 0.52 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 0.51 pyrazinamide
pncA 2290038 c.-797G>A upstream_gene_variant 0.5 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 0.5 pyrazinamide
pncA 2290069 c.-830_-828delAGCinsGGA upstream_gene_variant 0.38 pyrazinamide
pncA 2290072 c.-831T>C upstream_gene_variant 0.38 pyrazinamide
pncA 2290075 c.-834C>G upstream_gene_variant 0.38 pyrazinamide
pncA 2290084 c.-843T>C upstream_gene_variant 0.37 pyrazinamide
pncA 2290087 c.-846T>C upstream_gene_variant 0.37 pyrazinamide
pncA 2290230 c.-989T>C upstream_gene_variant 0.24 pyrazinamide
pncA 2290234 c.-993T>C upstream_gene_variant 0.24 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.66 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.55 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.55 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.44 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.4 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.34 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.33 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.33 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.33 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.27 isoniazid
kasA 2518053 c.-62_-60delATTinsCTG upstream_gene_variant 0.28 isoniazid
kasA 2518059 c.-56_-54delTCGinsACC upstream_gene_variant 0.27 isoniazid
kasA 2518089 c.-26C>A upstream_gene_variant 0.25 isoniazid
kasA 2518094 c.-21G>A upstream_gene_variant 0.24 isoniazid
kasA 2518100 c.-15T>G upstream_gene_variant 0.25 isoniazid
kasA 2518103 c.-12G>A upstream_gene_variant 0.24 isoniazid
kasA 2518110 c.-5T>A upstream_gene_variant 0.25 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 0.34 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.4 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.44 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.38 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.33 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.34 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.38 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.4 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.37 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.36 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.37 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 0.32 isoniazid
kasA 2518263 p.Phe50Tyr missense_variant 0.29 isoniazid
kasA 2518265 p.Val51Ile missense_variant 0.28 isoniazid
kasA 2518413 p.Ser100Asn missense_variant 0.28 isoniazid
kasA 2518421 p.Val103Leu missense_variant 0.38 isoniazid
kasA 2518429 c.315A>C synonymous_variant 0.4 isoniazid
kasA 2518439 p.Ala109Ser missense_variant 0.4 isoniazid
kasA 2518444 c.330T>C synonymous_variant 0.39 isoniazid
kasA 2518447 c.333T>G synonymous_variant 0.4 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.51 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.51 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.57 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.6 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.63 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.65 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.68 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.69 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.71 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.73 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.75 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.74 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.74 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.74 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.74 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.74 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.77 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.75 isoniazid
kasA 2518603 c.489G>C synonymous_variant 0.77 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.77 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.76 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.76 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.77 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.79 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.78 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.76 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.76 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.76 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.76 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.77 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.76 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.78 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.78 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.79 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.79 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.79 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.78 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.78 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.76 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.76 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.76 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.75 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.76 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.75 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.72 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.69 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.69 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.67 isoniazid
kasA 2518927 c.813C>G synonymous_variant 0.66 isoniazid
kasA 2518930 c.816G>C synonymous_variant 0.66 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.66 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.65 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.67 isoniazid
kasA 2518951 c.837G>C synonymous_variant 0.67 isoniazid
kasA 2518954 c.840C>G synonymous_variant 0.68 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.71 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.7 isoniazid
kasA 2518975 c.861C>G synonymous_variant 0.67 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.67 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.67 isoniazid
kasA 2518993 c.879C>G synonymous_variant 0.66 isoniazid
kasA 2518999 c.885G>A synonymous_variant 0.65 isoniazid
kasA 2519008 c.894C>G synonymous_variant 0.64 isoniazid
kasA 2519017 c.903G>C synonymous_variant 0.59 isoniazid
kasA 2519020 c.906G>C synonymous_variant 0.59 isoniazid
kasA 2519021 p.Ala303Lys missense_variant 0.59 isoniazid
kasA 2519027 p.Ile305Val missense_variant 0.59 isoniazid
kasA 2519050 c.936C>G synonymous_variant 0.66 isoniazid
kasA 2519053 c.939G>C synonymous_variant 0.66 isoniazid
kasA 2519056 c.942G>C synonymous_variant 0.65 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.66 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.67 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.69 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.61 isoniazid
kasA 2519108 p.Asp332Gln missense_variant 0.61 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.65 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.64 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.63 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.65 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.67 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.69 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 0.64 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 0.65 isoniazid
kasA 2519218 c.1104G>A synonymous_variant 0.63 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 0.64 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 0.63 isoniazid
kasA 2519230 c.1116C>T synonymous_variant 0.62 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 0.63 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.63 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 0.62 isoniazid
kasA 2519260 c.1146T>G synonymous_variant 0.59 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 0.58 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 0.57 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 0.57 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 0.57 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 0.56 isoniazid
kasA 2519295 p.Tyr394Phe missense_variant 0.49 isoniazid
kasA 2519299 c.1185C>T synonymous_variant 0.45 isoniazid
kasA 2519305 c.1191A>G synonymous_variant 0.46 isoniazid
kasA 2519306 p.Val398Ile missense_variant 0.47 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 0.39 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.39 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.4 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.4 isoniazid
ahpC 2726322 p.Pro44Ala missense_variant 0.41 isoniazid
ahpC 2726330 c.138G>A synonymous_variant 0.4 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 0.39 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.38 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.36 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 0.33 isoniazid
ahpC 2726378 c.186T>G synonymous_variant 0.27 isoniazid
ahpC 2726387 c.195C>T synonymous_variant 0.27 isoniazid
ahpC 2726390 c.198G>C synonymous_variant 0.27 isoniazid
ahpC 2726393 c.201G>C synonymous_variant 0.27 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 0.27 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 0.25 isoniazid
ahpC 2726468 c.276G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726528 c.336C>G synonymous_variant 0.3 isoniazid
ahpC 2726540 c.348C>G synonymous_variant 0.29 isoniazid
ahpC 2726543 c.351A>G synonymous_variant 0.29 isoniazid
ahpC 2726546 c.354C>G synonymous_variant 0.29 isoniazid
ahpC 2726551 p.Gln120Leu missense_variant 0.28 isoniazid
ahpC 2726556 p.Ala122Thr missense_variant 0.27 isoniazid Uncertain significance
ahpC 2726564 c.372C>G synonymous_variant 0.32 isoniazid Not assoc w R - Interim
ahpC 2726591 c.399C>G synonymous_variant 0.38 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.38 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.41 isoniazid
ahpC 2726601 p.Ile137Leu missense_variant 0.4 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.36 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.35 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.3 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.28 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.28 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.27 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.27 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.27 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.27 isoniazid
folC 2746285 c.1314T>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746308 p.Arg431Ser missense_variant 0.49 para-aminosalicylic_acid
folC 2746321 c.1278A>G synonymous_variant 0.57 para-aminosalicylic_acid
folC 2746328 p.Arg424Thr missense_variant 0.57 para-aminosalicylic_acid
folC 2746335 p.Gly422Arg missense_variant 0.58 para-aminosalicylic_acid
folC 2746336 c.1263C>G synonymous_variant 0.58 para-aminosalicylic_acid
folC 2746345 c.1254G>C synonymous_variant 0.59 para-aminosalicylic_acid
folC 2746351 p.Ala416Ser missense_variant 0.56 para-aminosalicylic_acid
folC 2746354 c.1245G>A synonymous_variant 0.62 para-aminosalicylic_acid
folC 2746363 p.Leu412Val missense_variant 0.65 para-aminosalicylic_acid
folC 2746375 c.1224G>C synonymous_variant 0.66 para-aminosalicylic_acid
folC 2746390 c.1209G>C synonymous_variant 0.66 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2746401 p.Ser400Ala missense_variant 0.65 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.65 para-aminosalicylic_acid
folC 2746414 p.Glu395Gln missense_variant 0.56 para-aminosalicylic_acid
folC 2746420 c.1179A>C synonymous_variant 0.52 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.56 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.58 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.53 para-aminosalicylic_acid
folC 2746471 c.1128C>A synonymous_variant 0.48 para-aminosalicylic_acid
folC 2746478 p.Phe374Tyr missense_variant 0.45 para-aminosalicylic_acid
folC 2746480 c.1119A>C synonymous_variant 0.47 para-aminosalicylic_acid
folC 2746492 c.1107G>A synonymous_variant 0.41 para-aminosalicylic_acid
folC 2746495 p.His368Gly missense_variant 0.41 para-aminosalicylic_acid
folC 2746507 c.1092A>G synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746510 c.1089A>G synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746516 c.1083T>G synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746519 p.Ser360Ala missense_variant 0.38 para-aminosalicylic_acid
folC 2746522 c.1077G>C synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746525 c.1074G>T synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746531 c.1068G>C synonymous_variant 0.41 para-aminosalicylic_acid
folC 2746534 c.1065T>C synonymous_variant 0.43 para-aminosalicylic_acid
folC 2746558 c.1041G>T synonymous_variant 0.42 para-aminosalicylic_acid
folC 2746564 c.1035A>G synonymous_variant 0.44 para-aminosalicylic_acid
folC 2746576 c.1023C>G synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746584 c.1015T>C synonymous_variant 0.32 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 0.24 para-aminosalicylic_acid
folC 2746651 c.948T>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.32 para-aminosalicylic_acid
folC 2746677 p.Ser308Ala missense_variant 0.27 para-aminosalicylic_acid
folC 2746678 c.921T>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746681 c.918C>G synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746687 c.912C>G synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746690 p.Val303Ala missense_variant 0.27 para-aminosalicylic_acid
folC 2746696 c.903C>T synonymous_variant 0.26 para-aminosalicylic_acid
folC 2746714 c.885T>A synonymous_variant 0.26 para-aminosalicylic_acid
folC 2746741 c.858C>T synonymous_variant 0.26 para-aminosalicylic_acid
folC 2746771 c.828A>G synonymous_variant 0.24 para-aminosalicylic_acid
folC 2747021 p.Val193Ala missense_variant 0.32 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 0.32 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 0.33 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 0.32 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.35 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.34 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.36 para-aminosalicylic_acid
folC 2747071 c.528C>G synonymous_variant 0.33 para-aminosalicylic_acid
folC 2747239 c.360T>C synonymous_variant 0.4 para-aminosalicylic_acid
folC 2747248 c.351G>C synonymous_variant 0.47 para-aminosalicylic_acid
folC 2747264 p.Gly112Ala missense_variant 0.53 para-aminosalicylic_acid
folC 2747266 c.333C>T synonymous_variant 0.53 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.55 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.55 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.55 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 0.55 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.57 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.61 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.63 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.63 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.64 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 0.53 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.51 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 0.45 para-aminosalicylic_acid
folC 2747410 c.187_188delAG frameshift_variant 0.44 para-aminosalicylic_acid
folC 2747415 c.184delCinsTTG frameshift_variant&missense_variant 0.43 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.42 para-aminosalicylic_acid
folC 2747422 c.177G>A synonymous_variant 0.42 para-aminosalicylic_acid
folC 2747425 c.174C>T synonymous_variant 0.42 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.43 para-aminosalicylic_acid
Rv2477c 2782396 c.1647G>A synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782423 c.1620C>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782432 p.Val537Ile missense_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782441 c.1602G>A synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782450 c.1593C>A synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782513 c.1530G>T synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782816 c.1227T>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782822 c.1221G>A synonymous_variant 0.3 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782828 c.1215T>C synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782841 p.Thr401Asn missense_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 0.5 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782894 c.1149C>G synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782930 c.1113G>A synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.62 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.6 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.63 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>A synonymous_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783047 p.Asp332Gly missense_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.66 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783107 c.936G>A synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.72 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.72 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.73 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.66 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Ala missense_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 0.52 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783431 c.610_612delAGCinsTCA synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783482 c.561C>T synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783497 c.544_546delTTGinsCTC synonymous_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.62 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.68 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783650 c.393C>T synonymous_variant 0.74 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783656 c.387G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>A synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783790 p.Val85Ile missense_variant 0.24 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Not assoc w R
amikacin Uncertain significance
Rv2477c 2783797 p.Asp82Glu missense_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.81 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.81 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.83 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.83 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.73 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.69 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.67 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784051 c.-9C>A upstream_gene_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784052 c.-10A>C upstream_gene_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784311 c.-269T>G upstream_gene_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784312 c.-270T>C upstream_gene_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784321 c.-279A>C upstream_gene_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784324 c.-282G>C upstream_gene_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784327 c.-285G>C upstream_gene_variant 0.34 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784345 c.-303G>A upstream_gene_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784354 c.-312T>C upstream_gene_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784357 c.-316_-315delTTinsAC upstream_gene_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784366 c.-324G>C upstream_gene_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784390 c.-348G>C upstream_gene_variant 0.61 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784435 c.-393C>G upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784507 c.-465C>G upstream_gene_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784511 c.-470_-469delAGinsGC upstream_gene_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784513 c.-471C>G upstream_gene_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784540 c.-498G>C upstream_gene_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
ribD 2986959 p.Leu41Val missense_variant 0.21 para-aminosalicylic_acid
ribD 2986978 p.Ser47Thr missense_variant 0.28 para-aminosalicylic_acid
ribD 2986983 p.Leu49Val missense_variant 0.29 para-aminosalicylic_acid
ribD 2986997 c.159T>C synonymous_variant 0.29 para-aminosalicylic_acid
ribD 2987001 p.Val55Ser missense_variant 0.29 para-aminosalicylic_acid
ribD 2987005 p.Asp56Gly missense_variant 0.29 para-aminosalicylic_acid
ribD 2987011 p.Thr58Ser missense_variant 0.29 para-aminosalicylic_acid
ribD 2987026 p.Ala63Gly missense_variant 0.28 para-aminosalicylic_acid
ribD 2987033 c.195C>G synonymous_variant 0.28 para-aminosalicylic_acid
ribD 2987042 c.204A>G synonymous_variant 0.27 para-aminosalicylic_acid
ribD 2987046 p.Val70Ile missense_variant 0.28 para-aminosalicylic_acid
ribD 2987058 c.220T>C synonymous_variant 0.28 para-aminosalicylic_acid
ribD 2987066 c.228A>G synonymous_variant 0.28 para-aminosalicylic_acid
ribD 2987069 c.231T>C synonymous_variant 0.29 para-aminosalicylic_acid
ribD 2987092 p.Val85Ala missense_variant 0.31 para-aminosalicylic_acid
ribD 2987105 c.267C>G synonymous_variant 0.2 para-aminosalicylic_acid
Rv2681 2996227 c.-512A>G upstream_gene_variant 0.3 capreomycin
Rv2680 2996233 c.129A>G synonymous_variant 0.31 capreomycin Not assoc w R - Interim
Rv2681 2996236 c.-503C>G upstream_gene_variant 0.3 capreomycin
Rv2681 2996239 c.-500C>T upstream_gene_variant 0.31 capreomycin
Rv2681 2996242 c.-497T>G upstream_gene_variant 0.3 capreomycin
Rv2681 2996248 c.-491A>G upstream_gene_variant 0.3 capreomycin
Rv2681 2996257 c.-482G>A upstream_gene_variant 0.36 capreomycin
Rv2681 2996260 c.-479G>C upstream_gene_variant 0.37 capreomycin
Rv2681 2996263 c.-476A>C upstream_gene_variant 0.37 capreomycin
Rv2681 2996269 c.-470G>C upstream_gene_variant 0.42 capreomycin
Rv2680 2996270 p.Tyr56His missense_variant 0.44 capreomycin
Rv2681 2996278 c.-461T>C upstream_gene_variant 0.48 capreomycin
Rv2681 2996287 c.-452A>C upstream_gene_variant 0.54 capreomycin
Rv2680 2996294 p.Ile64Val missense_variant 0.57 capreomycin
Rv2680 2996308 p.Glu68Asp missense_variant 0.58 capreomycin
Rv2680 2996310 p.Leu69Arg missense_variant 0.56 capreomycin
Rv2680 2996314 p.Asp70Glu missense_variant 0.57 capreomycin
Rv2680 2996315 p.Val71Ile missense_variant 0.58 capreomycin
Rv2681 2996320 c.-419T>C upstream_gene_variant 0.57 capreomycin
Rv2681 2996323 c.-416G>C upstream_gene_variant 0.57 capreomycin
Rv2681 2996326 c.-413G>A upstream_gene_variant 0.59 capreomycin
Rv2681 2996329 c.-410T>G upstream_gene_variant 0.6 capreomycin
Rv2680 2996335 p.Glu77Asp missense_variant 0.64 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.6 capreomycin
Rv2681 2996368 c.-371T>C upstream_gene_variant 0.57 capreomycin
Rv2681 2996374 c.-365G>C upstream_gene_variant 0.53 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 0.51 capreomycin
Rv2681 2996380 c.-359C>G upstream_gene_variant 0.53 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 0.53 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 0.51 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>G upstream_gene_variant 0.5 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.47 capreomycin
Rv2681 2996404 c.-335T>C upstream_gene_variant 0.47 capreomycin
Rv2680 2996408 p.Leu102Met missense_variant 0.45 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.42 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.41 capreomycin
Rv2681 2996434 c.-305G>C upstream_gene_variant 0.3 capreomycin
Rv2680 2996438 p.Ser112Pro missense_variant 0.28 capreomycin
Rv2681 2996443 c.-296T>C upstream_gene_variant 0.27 capreomycin
Rv2681 2996455 c.-284C>T upstream_gene_variant 0.26 capreomycin
Rv2681 2996473 c.-266G>A upstream_gene_variant 0.21 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 0.24 capreomycin Not assoc w R - Interim
Rv2681 2997137 c.399C>T synonymous_variant 0.24 capreomycin
Rv2681 2997149 c.411T>C synonymous_variant 0.25 capreomycin
Rv2681 2997152 c.414C>G synonymous_variant 0.25 capreomycin
Rv2681 2997155 c.417G>C synonymous_variant 0.29 capreomycin
Rv2681 2997173 p.Asp145Glu missense_variant 0.35 capreomycin
Rv2681 2997176 c.438A>C synonymous_variant 0.35 capreomycin
Rv2681 2997188 c.450G>C synonymous_variant 0.28 capreomycin
Rv2681 2997189 p.Ala151Thr missense_variant 0.28 capreomycin
Rv2681 2997242 c.504C>G synonymous_variant 0.43 capreomycin
Rv2681 2997260 c.522G>C synonymous_variant 0.38 capreomycin
Rv2681 2997263 c.525A>G synonymous_variant 0.36 capreomycin
Rv2681 2997267 p.Ser177Ala missense_variant 0.36 capreomycin
Rv2681 2997271 p.Ala178Glu missense_variant 0.36 capreomycin
Rv2681 2997278 c.540G>C synonymous_variant 0.36 capreomycin
Rv2681 2997287 c.549G>C synonymous_variant 0.35 capreomycin
Rv2681 2997291 c.553T>C synonymous_variant 0.35 capreomycin
Rv2681 2997317 c.579A>G synonymous_variant 0.28 capreomycin
Rv2681 2997330 p.Ser198Ala missense_variant 0.29 capreomycin
Rv2681 2997333 p.Arg199Glu missense_variant 0.29 capreomycin
Rv2681 2997338 c.600G>C synonymous_variant 0.27 capreomycin
Rv2681 2997346 p.Glu203Gly missense_variant 0.26 capreomycin
Rv2681 2997368 c.630T>C synonymous_variant 0.26 capreomycin
Rv2681 2997371 c.633G>A synonymous_variant 0.24 capreomycin
Rv2752c 3064860 c.1332G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064863 c.1329G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064872 c.1320T>G synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064877 p.Ser439Ala missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064881 p.Ser437Ala missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064887 c.1305A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064896 c.1296T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064914 c.1278T>G synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064926 c.1264_1266delTTGinsCTC synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064932 c.1260T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064935 c.1257A>G synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064941 p.Gln417Glu missense_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064947 c.1245A>G synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064956 p.Ser412Arg missense_variant 0.47 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3064962 c.1230C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064973 p.Ala407Ser missense_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064974 c.1218T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064995 c.1197C>G synonymous_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064998 c.1194A>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065007 c.1185G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065013 c.1179G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065018 p.Asn392His missense_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065022 c.1170G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065028 p.Val388Ile missense_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065040 c.1152C>G synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065052 c.1140G>A synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065082 c.1110G>T synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCGC synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065115 c.1077C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065126 p.Ser356Ala missense_variant 0.45 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065127 c.1065G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065131 p.Ala354Glu missense_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065133 c.1059T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065142 c.1050A>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065151 c.1041G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065166 c.1026C>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065183 p.Ser337Ala missense_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065186 c.1006T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065190 p.Ile334Val missense_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065196 c.996T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065202 c.990T>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065205 c.987T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065210 c.982T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065223 c.969T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065229 c.963G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065232 c.960T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065421 c.771G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065442 c.750T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065451 c.741G>A synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065457 c.735A>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065463 c.729T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065481 c.711T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065487 c.705T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065490 c.702A>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065493 c.699G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065496 c.696G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065499 c.693A>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065502 p.Asp230Glu missense_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065508 c.684T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065517 c.675C>G synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065520 c.672G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065532 c.660A>G synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065535 c.657C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065538 c.654G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065541 c.651A>G synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065553 c.639A>G synonymous_variant 0.49 levofloxacin
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065562 c.630T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065569 p.Ile208His missense_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065580 c.612G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065586 c.606C>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065607 c.585C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065612 p.Thr194Ala missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065616 c.576C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065622 c.570G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065625 c.567G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065634 c.558G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065637 c.555A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065640 c.552T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065646 c.546C>G synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065649 c.543T>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065659 p.Pro178Leu missense_variant 0.35 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065664 c.526_528delTTGinsCTT synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065667 c.525A>G synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065675 p.Phe173Leu missense_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065697 p.Ile165Val missense_variant 0.35 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065700 c.492C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065715 p.Tyr159His missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065901 c.291A>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065916 c.276T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065946 p.Gly82Ala missense_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065979 c.213T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065988 c.204A>G synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 0.58 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3066002 p.Met64Leu missense_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066003 c.189C>T synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid
rifampicin
ethambutol
Rv2752c 3066009 c.183G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066045 c.147T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066118 p.Asn25Ser missense_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066150 c.42C>A synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066249 c.-58C>T upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066261 c.-70G>C upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066270 c.-79G>A upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066276 c.-85G>A upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066282 c.-91G>T upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066291 c.-100G>A upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066351 c.-160G>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066357 c.-166G>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066360 c.-169T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066369 c.-180_-178delAGCinsGCG upstream_gene_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066435 c.-246_-244delGGTinsAAC upstream_gene_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066452 c.-261T>A upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066561 c.-370A>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066572 c.-381G>A upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066638 c.-447T>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066641 c.-450G>T upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066642 c.-451G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066645 c.-454G>A upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066657 c.-466C>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066665 c.-474G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066672 c.-483_-481delGTGinsATC upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066676 c.-485C>T upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066684 c.-495_-493delGGGinsCCC upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066696 c.-505T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066704 c.-513C>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066707 c.-516A>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066713 c.-522C>T upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066714 c.-523G>A upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066734 c.-543G>A upstream_gene_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066744 c.-553C>G upstream_gene_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066747 c.-558_-556delCAAinsATC upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066756 c.-567_-565delCGGinsAGC upstream_gene_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066762 c.-571G>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066768 c.-577G>A upstream_gene_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.52 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.55 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066855 c.-664T>C upstream_gene_variant 0.51 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066954 c.-763G>A upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066969 c.-778G>C upstream_gene_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066981 c.-790T>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066987 c.-796C>T upstream_gene_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067223 c.723G>C synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067232 c.714C>G synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067246 p.Thr234Ala missense_variant 0.54 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 0.55 para-aminosalicylic_acid
thyX 3067250 p.Val232Ile missense_variant 0.55 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067281 p.Val222Ala missense_variant 0.54 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.55 para-aminosalicylic_acid
thyX 3067286 c.660C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067313 c.633G>T synonymous_variant 0.63 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.68 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067462 c.484C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.75 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067490 p.Ala152Glu missense_variant 0.75 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067510 c.436C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.76 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.74 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.73 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.73 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.74 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.77 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.77 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067598 c.348C>T synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.73 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.76 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067665 p.Ile94Thr missense_variant 0.74 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067691 p.Ile85Leu missense_variant 0.72 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.75 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.76 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.67 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067877 c.69G>C synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.59 para-aminosalicylic_acid
thyX 3067935 p.Thr4Ile missense_variant 0.36 para-aminosalicylic_acid
thyX 3067951 c.-6A>G upstream_gene_variant 0.22 para-aminosalicylic_acid
thyA 3073815 c.657G>A synonymous_variant 0.27 para-aminosalicylic_acid
thyA 3073824 c.648A>G synonymous_variant 0.32 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3073872 p.Ile200Val missense_variant 0.43 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.44 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.46 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073941 c.531C>T synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3074100 p.Asp124Asn missense_variant 0.28 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074109 c.363C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3074147 p.Ile109Val missense_variant 0.36 para-aminosalicylic_acid
thyA 3074157 p.Ser105Thr missense_variant 0.33 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074163 p.Ala103Thr missense_variant 0.34 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.38 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074262 p.Gly70Ala missense_variant 0.32 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.3 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.3 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087649 p.Gly277Asp missense_variant 0.25 cycloserine
ald 3087656 c.837A>G synonymous_variant 0.26 cycloserine
ald 3087672 p.His285Asp missense_variant 0.36 cycloserine
ald 3087680 c.861G>C synonymous_variant 0.41 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.42 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.43 cycloserine
ald 3087726 p.Ala303Ser missense_variant 0.36 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.36 cycloserine
ald 3087737 c.918G>C synonymous_variant 0.36 cycloserine
ald 3087749 c.930C>G synonymous_variant 0.37 cycloserine
ald 3087750 p.Tyr311Val missense_variant 0.37 cycloserine
ald 3087761 c.942C>G synonymous_variant 0.37 cycloserine
ald 3087770 c.951G>C synonymous_variant 0.38 cycloserine
ald 3087787 p.Glu323Ala missense_variant 0.27 cycloserine
ald 3087791 c.972T>C synonymous_variant 0.27 cycloserine
ald 3087799 p.His327Arg missense_variant 0.26 cycloserine
ald 3087809 c.990G>T synonymous_variant 0.26 cycloserine
whiB7 3569181 c.-502C>T upstream_gene_variant 0.27 kanamycin
amikacin
streptomycin
whiB7 3569197 c.-518C>A upstream_gene_variant 0.23 kanamycin
amikacin
streptomycin
lpqB 3623393 c.1518A>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623411 c.1500T>C synonymous_variant 0.43 rifampicin
bedaquiline
lpqB 3623417 c.1494A>C synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3623423 c.1488C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623428 c.1483T>C synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623441 p.Ser490Asn missense_variant 0.41 rifampicin
bedaquiline
lpqB 3623444 c.1467T>C synonymous_variant 0.41 rifampicin
bedaquiline
lpqB 3623449 c.1462C>T synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623456 c.1455T>C synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623465 c.1446G>C synonymous_variant 0.41 rifampicin
bedaquiline
lpqB 3623468 c.1443T>A synonymous_variant 0.41 rifampicin
bedaquiline
lpqB 3623471 c.1440C>T synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3623474 c.1437C>G synonymous_variant 0.41 rifampicin
bedaquiline
lpqB 3623477 c.1434G>C synonymous_variant 0.4 rifampicin
bedaquiline
lpqB 3623480 c.1431C>G synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3623484 p.Phe476Tyr missense_variant 0.45 rifampicin
bedaquiline
lpqB 3623492 c.1419T>C synonymous_variant 0.51 rifampicin
bedaquiline
lpqB 3623512 p.Gly467Ser missense_variant 0.55 rifampicin
bedaquiline
lpqB 3623531 c.1380T>C synonymous_variant 0.56 rifampicin
bedaquiline
lpqB 3623549 c.1362C>G synonymous_variant 0.43 rifampicin
bedaquiline
lpqB 3623555 p.Gly452Ser missense_variant 0.44 rifampicin
bedaquiline
lpqB 3623561 c.1350T>C synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623570 c.1341A>G synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623573 c.1338T>G synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623576 c.1335T>C synonymous_variant 0.45 rifampicin
bedaquiline
lpqB 3623580 p.Asn444Thr missense_variant 0.44 rifampicin
bedaquiline
lpqB 3623587 p.Ala442Pro missense_variant 0.44 rifampicin
bedaquiline
lpqB 3623597 c.1314C>G synonymous_variant 0.47 rifampicin
bedaquiline
lpqB 3623601 p.Ser437Thr missense_variant 0.5 rifampicin
bedaquiline
lpqB 3623612 p.Thr433Val missense_variant 0.52 rifampicin
bedaquiline
lpqB 3623630 c.1281G>C synonymous_variant 0.56 rifampicin
bedaquiline
lpqB 3623648 c.1263A>G synonymous_variant 0.44 rifampicin
bedaquiline
lpqB 3623654 p.Asp419Glu missense_variant 0.42 rifampicin
bedaquiline
lpqB 3623660 c.1251A>C synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3623666 c.1245A>G synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623669 c.1242G>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623676 p.Val412Asn missense_variant 0.34 rifampicin
bedaquiline
lpqB 3623682 p.Thr410Gly missense_variant 0.34 rifampicin
bedaquiline
lpqB 3623684 c.1227T>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623703 p.Ala403Val missense_variant 0.38 rifampicin
bedaquiline
lpqB 3623720 p.Ser397Thr missense_variant 0.39 rifampicin
bedaquiline
lpqB 3623726 c.1185G>A synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3623942 c.969A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623953 c.958T>C synonymous_variant 0.46 rifampicin
bedaquiline
lpqB 3623962 c.949T>C synonymous_variant 0.47 rifampicin
bedaquiline
lpqB 3623966 c.945G>C synonymous_variant 0.5 rifampicin
bedaquiline
lpqB 3623970 p.Ala314Gly missense_variant 0.51 rifampicin
bedaquiline
lpqB 3623972 c.939C>G synonymous_variant 0.5 rifampicin
bedaquiline
lpqB 3623975 c.936T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623987 c.924G>C synonymous_variant 0.51 rifampicin
bedaquiline
lpqB 3623990 c.921G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3623993 c.918C>T synonymous_variant 0.54 rifampicin
bedaquiline
lpqB 3624014 c.897T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624026 p.Glu295Asp missense_variant 0.56 rifampicin
bedaquiline
lpqB 3624030 p.Ala294Arg missense_variant 0.58 rifampicin
bedaquiline
lpqB 3624032 c.879T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624035 c.874_876delAGGinsCGA synonymous_variant 0.6 rifampicin
bedaquiline
lpqB 3624041 p.Glu290Asp missense_variant 0.62 rifampicin
bedaquiline
lpqB 3624050 c.861C>G synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624077 c.834G>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624082 c.829A>C synonymous_variant 0.72 rifampicin
bedaquiline
lpqB 3624092 c.817_819delAGGinsCGC synonymous_variant 0.68 rifampicin
bedaquiline
lpqB 3624100 c.811T>C synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624101 c.810C>G synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624116 c.795A>G synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624119 c.792C>G synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624124 p.Leu263Val missense_variant 0.67 rifampicin
bedaquiline
lpqB 3624125 c.786A>G synonymous_variant 0.67 rifampicin
bedaquiline
lpqB 3624143 c.768T>C synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624166 p.Met249Leu missense_variant 0.69 rifampicin
bedaquiline
lpqB 3624167 c.744C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624173 c.738A>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624179 c.732C>G synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624185 c.726C>T synonymous_variant 0.69 rifampicin
bedaquiline
lpqB 3624194 c.717C>G synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624200 c.711A>G synonymous_variant 0.63 rifampicin
bedaquiline
lpqB 3624204 p.Ser236Asn missense_variant 0.61 rifampicin
bedaquiline
lpqB 3624209 c.702A>C synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624224 c.687T>C synonymous_variant 0.52 rifampicin
bedaquiline
lpqB 3624242 c.669A>G synonymous_variant 0.45 rifampicin
bedaquiline
lpqB 3624245 c.666A>G synonymous_variant 0.45 rifampicin
bedaquiline
lpqB 3624254 c.657T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624263 c.648T>C synonymous_variant 0.35 rifampicin
bedaquiline
lpqB 3624266 c.645T>C synonymous_variant 0.35 rifampicin
bedaquiline
lpqB 3624269 c.642G>C synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3624276 p.Arg212His missense_variant 0.34 rifampicin
bedaquiline
lpqB 3624339 p.Arg191His missense_variant 0.36 rifampicin
bedaquiline
lpqB 3624346 p.Ser189Pro missense_variant 0.39 rifampicin
bedaquiline
lpqB 3624356 c.555C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624371 c.540T>C synonymous_variant 0.58 rifampicin
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 0.63 rifampicin
bedaquiline
lpqB 3624404 c.507G>T synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624407 c.504C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624410 c.501C>T synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624416 c.495G>A synonymous_variant 0.6 rifampicin
bedaquiline
lpqB 3624422 c.489G>C synonymous_variant 0.6 rifampicin
bedaquiline
lpqB 3624425 p.Glu162Ala missense_variant 0.6 rifampicin
bedaquiline
lpqB 3624428 c.483A>G synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624437 c.474G>A synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624461 c.450C>G synonymous_variant 0.7 rifampicin
bedaquiline
lpqB 3624464 c.447A>G synonymous_variant 0.68 rifampicin
bedaquiline
lpqB 3624470 c.441T>C synonymous_variant 0.66 rifampicin
bedaquiline
lpqB 3624482 c.429T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624485 p.Asp142Gly missense_variant 0.55 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3624491 c.420G>C synonymous_variant 0.52 rifampicin
bedaquiline
lpqB 3624512 c.399C>G synonymous_variant 0.35 rifampicin
bedaquiline
lpqB 3624515 c.396G>C synonymous_variant 0.3 rifampicin
bedaquiline
lpqB 3624632 c.279G>C synonymous_variant 0.3 rifampicin
bedaquiline
lpqB 3624646 c.265T>C synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3624656 c.255C>T synonymous_variant 0.45 rifampicin
bedaquiline
lpqB 3624671 p.Ala80Ser missense_variant 0.47 rifampicin
bedaquiline
lpqB 3624680 c.231T>G synonymous_variant 0.48 rifampicin
bedaquiline
lpqB 3624686 p.Glu75Gln missense_variant 0.48 rifampicin
bedaquiline
lpqB 3624689 c.222C>T synonymous_variant 0.49 rifampicin
bedaquiline
lpqB 3624701 c.210T>C synonymous_variant 0.51 rifampicin
bedaquiline
lpqB 3624704 c.207G>C synonymous_variant 0.52 rifampicin
bedaquiline
lpqB 3624707 c.204G>C synonymous_variant 0.57 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.64 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 0.65 rifampicin
bedaquiline
lpqB 3624770 c.141T>C synonymous_variant 0.64 rifampicin
bedaquiline
lpqB 3624776 c.135T>C synonymous_variant 0.62 rifampicin
bedaquiline
lpqB 3624783 p.Ser43Thr missense_variant 0.58 rifampicin
bedaquiline
lpqB 3624788 c.123A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 0.51 rifampicin
bedaquiline
lpqB 3624807 p.Val35Ala missense_variant 0.45 rifampicin
bedaquiline
lpqB 3624812 c.99T>G synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3624815 c.96A>G synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3624824 c.87A>C synonymous_variant 0.38 rifampicin
bedaquiline
lpqB 3624830 c.81C>G synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3624833 c.78A>G synonymous_variant 0.35 rifampicin
bedaquiline
lpqB 3624839 c.72C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624847 p.Thr22Ser missense_variant 0.25 rifampicin
bedaquiline
lpqB 3624848 c.63C>T synonymous_variant 0.25 rifampicin
bedaquiline
lpqB 3625051 c.-141C>T upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625057 c.-147C>G upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625060 c.-150G>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3625069 c.-159T>G upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrB 3625087 p.Ala509Ser missense_variant 0.46 rifampicin
bedaquiline
mtrB 3625093 p.Glu507Asp missense_variant 0.48 rifampicin
bedaquiline
lpqB 3625099 c.-189C>G upstream_gene_variant 0.52 rifampicin
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.57 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.56 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrB 3625135 c.1479A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 0.54 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 0.58 rifampicin
bedaquiline
lpqB 3625153 c.-243C>T upstream_gene_variant 0.58 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625165 c.-255G>C upstream_gene_variant 0.63 rifampicin
bedaquiline
lpqB 3625186 c.-276T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.64 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625206 p.Ser470Ala missense_variant 0.63 rifampicin
bedaquiline
lpqB 3625218 c.-308C>A upstream_gene_variant 0.59 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625225 c.-315G>C upstream_gene_variant 0.58 rifampicin
bedaquiline
lpqB 3625240 c.-330T>C upstream_gene_variant 0.54 rifampicin
bedaquiline
lpqB 3625243 c.-333T>G upstream_gene_variant 0.54 rifampicin
bedaquiline
lpqB 3625246 c.-336G>C upstream_gene_variant 0.55 rifampicin
bedaquiline
lpqB 3625255 c.-345T>C upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3625261 c.1353C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 0.46 rifampicin
bedaquiline
lpqB 3625279 c.-369C>G upstream_gene_variant 0.48 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrB 3625301 p.Ala438Gly missense_variant 0.42 rifampicin
bedaquiline
lpqB 3625510 c.-600T>C upstream_gene_variant 0.37 rifampicin
bedaquiline
lpqB 3625513 c.-603G>C upstream_gene_variant 0.39 rifampicin
bedaquiline
lpqB 3625518 c.-608T>C upstream_gene_variant 0.42 rifampicin
bedaquiline
lpqB 3625525 c.-615G>C upstream_gene_variant 0.49 rifampicin
bedaquiline
lpqB 3625528 c.-618G>T upstream_gene_variant 0.52 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 0.56 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 0.6 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.68 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.71 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.75 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.77 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 0.76 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrB 3625636 c.978C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.76 rifampicin
bedaquiline
lpqB 3625696 c.-786A>G upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3625705 c.909C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625714 c.-804C>T upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625749 c.-839C>T upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.72 rifampicin Uncertain significance
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625792 c.-882G>A upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3625797 p.Val273Met missense_variant 0.74 rifampicin Uncertain significance
bedaquiline Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625848 c.766C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625849 c.-939T>C upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625876 c.738G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625882 c.732G>A synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625900 c.-990G>C upstream_gene_variant 0.51 rifampicin
bedaquiline
lpqB 3625903 c.-993G>C upstream_gene_variant 0.47 rifampicin
bedaquiline
lpqB 3625909 c.-999T>C upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3625918 c.696G>T synonymous_variant 0.35 rifampicin
bedaquiline
mtrB 3625923 c.691C>T synonymous_variant 0.31 rifampicin
bedaquiline
mtrB 3625927 c.687T>C synonymous_variant 0.25 rifampicin
bedaquiline
mtrB 3625930 c.684C>G synonymous_variant 0.24 rifampicin
bedaquiline
mtrB 3625936 c.678C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626048 p.Arg189Gln missense_variant 0.36 rifampicin
bedaquiline
mtrB 3626053 p.Leu187Ser missense_variant 0.37 rifampicin
bedaquiline
mtrB 3626058 p.Thr186Ala missense_variant 0.37 rifampicin
bedaquiline
mtrB 3626062 c.552T>C synonymous_variant 0.37 rifampicin
bedaquiline
mtrB 3626065 c.549G>C synonymous_variant 0.37 rifampicin
bedaquiline
mtrB 3626070 p.Ile182Val missense_variant 0.42 rifampicin
bedaquiline
mtrB 3626077 c.537C>G synonymous_variant 0.43 rifampicin
bedaquiline
mtrB 3626083 c.531G>C synonymous_variant 0.44 rifampicin
bedaquiline
mtrB 3626086 c.528C>G synonymous_variant 0.45 rifampicin
bedaquiline
mtrB 3626092 c.522T>G synonymous_variant 0.49 rifampicin
bedaquiline
mtrB 3626095 p.Glu173Asp missense_variant 0.51 rifampicin
bedaquiline
mtrB 3626101 p.Gln171His missense_variant 0.51 rifampicin
bedaquiline
mtrB 3626107 c.507G>A synonymous_variant 0.52 rifampicin
bedaquiline
mtrB 3626110 c.504C>G synonymous_variant 0.53 rifampicin
bedaquiline
mtrB 3626122 p.Ala164Ser missense_variant 0.53 rifampicin
bedaquiline
mtrB 3626154 c.460C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626155 p.Ala153Ser missense_variant 0.48 rifampicin
bedaquiline
mtrB 3626158 c.456C>T synonymous_variant 0.47 rifampicin
bedaquiline
mtrB 3626170 c.444T>C synonymous_variant 0.47 rifampicin
bedaquiline
mtrB 3626179 c.435A>C synonymous_variant 0.44 rifampicin
bedaquiline
mtrB 3626185 c.429T>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626188 p.Ser142Thr missense_variant 0.32 rifampicin
bedaquiline
mtrB 3626194 c.420T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626203 c.411G>A synonymous_variant 0.31 rifampicin
bedaquiline
mtrB 3626206 c.408T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626209 c.405T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626687 c.-74G>T upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.57 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626840 c.-227C>G upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrA 3626869 c.481C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3626912 c.-299T>G upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3626927 c.-314G>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrA 3626939 c.411A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3626945 c.-332C>T upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3627065 c.-452G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627071 c.279G>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627074 c.-461G>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrA 3627146 c.204C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTA upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.59 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.53 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3627375 c.-762C>G upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrB 3627377 c.-764G>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3627380 c.-767T>C upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrA 3627837 c.-488G>C upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrA 3627839 c.-490T>C upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrA 3627857 c.-508G>C upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrA 3627860 c.-511G>C upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrA 3627872 c.-523T>C upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrA 3627875 c.-526G>C upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrA 3627881 c.-532G>C upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrA 3627884 c.-535A>G upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrA 3627887 c.-538C>G upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrA 3627893 c.-544T>G upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrA 3627917 c.-568G>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrA 3627920 c.-571A>G upstream_gene_variant 0.32 rifampicin
bedaquiline
fbiB 3640839 c.-696C>G upstream_gene_variant 0.3 pretomanid
delamanid
clofazimine
fbiA 3640850 p.Glu103Gly missense_variant 0.4 pretomanid
delamanid
clofazimine
fbiB 3640857 c.-678G>C upstream_gene_variant 0.44 pretomanid
delamanid
clofazimine
fbiB 3640866 c.-669T>C upstream_gene_variant 0.45 pretomanid
delamanid
clofazimine
fbiA 3640871 p.Ala110Gly missense_variant 0.43 pretomanid
delamanid
clofazimine
fbiB 3640878 c.-657T>C upstream_gene_variant 0.42 pretomanid
delamanid
clofazimine
fbiB 3640899 c.-636G>C upstream_gene_variant 0.4 pretomanid
delamanid
clofazimine
fbiA 3640900 p.Gln120Asn missense_variant 0.4 pretomanid
delamanid
clofazimine
fbiB 3640914 c.-621C>G upstream_gene_variant 0.39 pretomanid
delamanid
clofazimine
fbiB 3640920 c.-615A>G upstream_gene_variant 0.4 pretomanid
delamanid
clofazimine
fbiA 3640930 p.Glu130Thr missense_variant 0.36 pretomanid
delamanid
clofazimine
fbiB 3640935 c.-600C>G upstream_gene_variant 0.36 pretomanid
delamanid
clofazimine
fbiB 3640938 c.-597A>G upstream_gene_variant 0.35 pretomanid
delamanid
clofazimine
fbiA 3640943 p.Asp134Ala missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiB 3640962 c.-573C>G upstream_gene_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3640965 c.-570C>G upstream_gene_variant 0.25 pretomanid
delamanid
clofazimine
fbiA 3640976 p.Ala145Val missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiB 3641178 c.-357G>C upstream_gene_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3641184 c.-351T>G upstream_gene_variant 0.28 pretomanid
delamanid
clofazimine
fbiB 3641196 c.-339C>G upstream_gene_variant 0.32 pretomanid
delamanid
clofazimine
fbiA 3641200 p.Ile220Val missense_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3641217 c.-318C>G upstream_gene_variant 0.36 pretomanid
delamanid
clofazimine
fbiB 3641226 c.-309G>C upstream_gene_variant 0.35 pretomanid
delamanid
clofazimine
fbiA 3641227 p.Ile229Val missense_variant 0.36 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiA 3641234 p.Ala231Gly missense_variant 0.36 pretomanid
delamanid
clofazimine
fbiB 3641239 c.-296T>C upstream_gene_variant 0.36 pretomanid
delamanid
clofazimine
fbiA 3641246 p.Glu235Ala missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiB 3641250 c.-285A>G upstream_gene_variant 0.35 pretomanid
delamanid
clofazimine
fbiA 3641252 p.Thr237Lys missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiB 3641256 c.-279A>C upstream_gene_variant 0.35 pretomanid
delamanid
clofazimine
fbiA 3641260 p.Ile240Val missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiA 3641286 c.744C>T synonymous_variant 0.38 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiA 3641288 p.Glu249Gly missense_variant 0.38 pretomanid
delamanid
clofazimine
fbiA 3641314 p.Thr258Ala missense_variant 0.26 pretomanid
delamanid
clofazimine
fbiB 3641840 c.306T>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiB 3641846 c.312G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3641852 c.318C>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiB 3641864 c.330A>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3641876 c.342C>G synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3641879 c.345G>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiB 3641880 p.Ser116Asp missense_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3641888 c.354A>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3641891 c.357G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3641900 c.366G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3641906 c.372T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3641909 c.375T>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiB 3641914 p.Ala127Gly missense_variant 0.34 pretomanid
delamanid
clofazimine
fbiB 3641918 c.384T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3641924 c.390A>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3641927 c.393C>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3641928 c.394T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3641938 p.Gly135Ala missense_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3641961 p.Thr143Glu missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3641972 c.438G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3642542 c.1008A>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiB 3642560 c.1026T>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiB 3642566 c.1032A>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiB 3642581 c.1047A>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiB 3642587 p.Met351Ile missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiB 3642593 c.1059G>T synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiB 3642602 c.1068A>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiB 3642605 c.1071A>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiB 3642609 c.1075_1076delAGinsTC synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiB 3642614 c.1080C>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiB 3642617 c.1083C>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiB 3642620 c.1086T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiB 3642656 c.1122G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiB 3642659 c.1125C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiB 3642668 c.1134A>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiB 3642671 c.1137G>A synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiB 3642677 c.1143A>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiB 3642680 c.1146A>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiB 3642684 c.1150T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiB 3642701 c.1167C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiB 3642719 c.1185T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiB 3642731 c.1197C>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiB 3642743 c.1209T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiB 3642749 c.1215T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiB 3642758 c.1224C>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiB 3642763 p.Asp410Ala missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiB 3642770 c.1236G>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiB 3642779 c.1245A>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiB 3642781 p.Val416Ala missense_variant 0.39 pretomanid
delamanid
clofazimine
fbiB 3642809 c.1275G>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
alr 3840926 c.495T>C synonymous_variant 0.21 cycloserine
alr 3840944 c.477T>C synonymous_variant 0.34 cycloserine
alr 3840947 c.474G>C synonymous_variant 0.38 cycloserine
alr 3840959 c.462G>C synonymous_variant 0.46 cycloserine
alr 3840968 c.453G>C synonymous_variant 0.44 cycloserine
alr 3840980 c.441G>C synonymous_variant 0.43 cycloserine
alr 3840989 c.432G>C synonymous_variant 0.43 cycloserine
alr 3840994 p.His143Asp missense_variant 0.43 cycloserine
alr 3840995 c.424_426delTTGinsCTC synonymous_variant 0.43 cycloserine
alr 3841001 c.420A>G synonymous_variant 0.45 cycloserine
alr 3841010 c.411A>G synonymous_variant 0.46 cycloserine
alr 3841017 p.Leu135Glu missense_variant 0.45 cycloserine
alr 3841022 c.399C>G synonymous_variant 0.45 cycloserine
alr 3841028 c.393G>C synonymous_variant 0.44 cycloserine
alr 3841033 p.Val130Ile missense_variant 0.44 cycloserine
alr 3841037 c.384G>C synonymous_variant 0.43 cycloserine
alr 3841059 p.Gly121Ala missense_variant 0.41 cycloserine
alr 3841069 p.Ile118Phe missense_variant 0.39 cycloserine
alr 3841079 c.342T>C synonymous_variant 0.31 cycloserine
rpoA 3877482 c.1026C>G synonymous_variant 0.36 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 0.41 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.5 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.53 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.57 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.69 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.71 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.76 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.78 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.76 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.76 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.74 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.71 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.71 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.7 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.69 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.71 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.71 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.71 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.72 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.69 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.7 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.72 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.69 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.68 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 0.65 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.64 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.63 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.62 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.62 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.61 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.63 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878094 c.414C>G synonymous_variant 0.65 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.63 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.61 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.62 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.61 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.61 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.62 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.65 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.68 rifampicin
rpoA 3878181 c.327C>T synonymous_variant 0.71 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.71 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.71 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.73 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.72 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.73 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.75 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.74 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878340 c.168C>T synonymous_variant 0.72 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 0.74 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.72 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.72 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.74 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.72 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.71 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.72 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.68 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.66 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.64 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.62 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.59 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.57 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.55 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.56 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.55 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.49 rifampicin
rpoA 3878672 c.-165A>T upstream_gene_variant 0.37 rifampicin
rpoA 3878683 c.-176G>C upstream_gene_variant 0.52 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 0.62 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.66 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.63 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.63 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.65 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.65 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.66 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.67 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.69 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.74 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.74 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.75 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.75 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.76 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.73 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.72 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.74 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.74 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.76 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.77 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.76 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.77 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.75 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.76 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 0.77 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.76 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.77 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.78 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.79 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.78 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.79 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.75 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.75 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.73 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.72 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.7 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.63 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.61 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.55 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.53 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.47 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.46 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.46 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.46 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.57 pretomanid
delamanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.51 pretomanid
delamanid
ddn 3986646 c.-198_-196delCTCinsTTG upstream_gene_variant 0.51 pretomanid
delamanid
ddn 3986665 c.-179G>C upstream_gene_variant 0.39 pretomanid
delamanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.37 pretomanid
delamanid
ddn 3986672 c.-172G>A upstream_gene_variant 0.35 pretomanid
delamanid
ddn 3986673 c.-171C>T upstream_gene_variant 0.35 pretomanid
delamanid
ddn 3986681 c.-163C>G upstream_gene_variant 0.35 pretomanid
delamanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.34 pretomanid
delamanid
ddn 3986696 c.-148G>C upstream_gene_variant 0.34 pretomanid
delamanid
clpC1 4038212 c.2493T>C synonymous_variant 0.33 pyrazinamide
clpC1 4038239 c.2466T>C synonymous_variant 0.57 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 0.56 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.57 pyrazinamide
clpC1 4038272 p.Gly811Ser missense_variant 0.57 pyrazinamide
clpC1 4038275 c.2430A>G synonymous_variant 0.58 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.6 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.65 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.66 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.66 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.66 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.66 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.65 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.68 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.67 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.66 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.64 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.65 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.67 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.68 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.64 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.65 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.65 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.65 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.7 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.7 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.67 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.65 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.63 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.62 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.67 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.68 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.72 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.68 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.73 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.73 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.72 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.71 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.75 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.74 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.74 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.74 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038749 c.1956C>A synonymous_variant 0.74 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.75 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.74 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.75 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.77 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4038893 c.1812C>T synonymous_variant 0.74 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.74 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.75 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.75 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.72 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.75 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.73 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.75 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4039229 c.1476C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.74 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.7 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.68 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.69 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.69 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.68 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.61 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.62 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.61 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.6 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.56 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.56 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.59 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.6 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.64 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.61 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.64 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.65 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.67 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.63 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.67 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.68 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.67 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.66 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.62 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.71 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.77 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4039988 c.717C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.75 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.76 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.69 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.72 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.69 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.7 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.65 pyrazinamide
clpC1 4040210 c.495G>C synonymous_variant 0.65 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.66 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.7 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.71 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.73 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.72 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.76 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 0.67 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.71 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.69 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.67 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.67 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.66 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.68 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.66 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.61 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.62 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.65 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.68 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.69 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.68 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.66 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.66 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.65 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.65 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>T synonymous_variant 0.69 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.68 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.64 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.56 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.52 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.5 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.37 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.36 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.38 pyrazinamide
clpC1 4040596 c.109C>T synonymous_variant 0.38 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.37 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.38 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.37 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.37 pyrazinamide
clpC1 4040841 c.-138delG upstream_gene_variant 0.98 pyrazinamide
panD 4043865 p.Gly139Arg missense_variant 0.35 pyrazinamide Uncertain significance
panD 4043872 p.Gly137Val missense_variant 0.36 pyrazinamide Uncertain significance
panD 4043876 p.Leu136Ile missense_variant 0.36 pyrazinamide
panD 4043883 c.399C>T synonymous_variant 0.36 pyrazinamide
panD 4043886 c.396A>G synonymous_variant 0.37 pyrazinamide
panD 4043896 p.Gly129Ala missense_variant 0.37 pyrazinamide
panD 4043903 p.Asn127Asp missense_variant 0.36 pyrazinamide
panD 4043913 c.369T>C synonymous_variant 0.35 pyrazinamide
panD 4043916 c.366A>G synonymous_variant 0.35 pyrazinamide
panD 4043922 c.360T>C synonymous_variant 0.36 pyrazinamide
panD 4043931 p.Met117Leu missense_variant 0.36 pyrazinamide
panD 4043939 p.Ile115Val missense_variant 0.37 pyrazinamide
panD 4043951 p.Tyr111Asp missense_variant 0.35 pyrazinamide
panD 4043952 c.330T>C synonymous_variant 0.35 pyrazinamide
panD 4043961 c.321T>C synonymous_variant 0.32 pyrazinamide
panD 4043964 c.318G>C synonymous_variant 0.32 pyrazinamide
panD 4044057 c.225C>A synonymous_variant 0.2 pyrazinamide
panD 4044072 c.210C>G synonymous_variant 0.37 pyrazinamide
panD 4044075 c.207T>C synonymous_variant 0.38 pyrazinamide
panD 4044081 c.201T>C synonymous_variant 0.42 pyrazinamide
panD 4044084 c.198T>C synonymous_variant 0.44 pyrazinamide
panD 4044105 c.177G>C synonymous_variant 0.46 pyrazinamide
panD 4044117 c.165G>C synonymous_variant 0.44 pyrazinamide
panD 4044120 c.162A>C synonymous_variant 0.44 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.44 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 0.43 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 0.5 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.49 pyrazinamide
panD 4044174 c.108C>G synonymous_variant 0.46 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
panD 4044188 c.94T>C synonymous_variant 0.46 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.46 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.46 pyrazinamide
panD 4044213 c.69C>G synonymous_variant 0.34 pyrazinamide
panD 4044635 c.-354G>C upstream_gene_variant 0.46 pyrazinamide
panD 4044643 c.-362G>T upstream_gene_variant 0.45 pyrazinamide
panD 4044647 c.-366C>G upstream_gene_variant 0.44 pyrazinamide
panD 4044650 c.-369G>C upstream_gene_variant 0.44 pyrazinamide
panD 4044662 c.-381C>G upstream_gene_variant 0.46 pyrazinamide
panD 4044668 c.-387G>C upstream_gene_variant 0.45 pyrazinamide
panD 4044672 c.-392_-391delGCinsCA upstream_gene_variant 0.43 pyrazinamide
panD 4044675 c.-394T>C upstream_gene_variant 0.44 pyrazinamide
panD 4044677 c.-396T>C upstream_gene_variant 0.45 pyrazinamide
panD 4044682 c.-401C>A upstream_gene_variant 0.49 pyrazinamide
panD 4044688 c.-407T>C upstream_gene_variant 0.52 pyrazinamide
panD 4044692 c.-411G>C upstream_gene_variant 0.51 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 0.55 pyrazinamide
panD 4044704 c.-423G>C upstream_gene_variant 0.57 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.58 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.62 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.69 pyrazinamide
panD 4044746 c.-467_-465delGTGinsATC upstream_gene_variant 0.67 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.68 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.62 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.61 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.61 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.6 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.6 pyrazinamide
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 0.6 pyrazinamide
panD 4044823 c.-542G>C upstream_gene_variant 0.6 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.63 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.68 pyrazinamide
panD 4044848 c.-567T>A upstream_gene_variant 0.67 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.68 pyrazinamide
panD 4044860 c.-579C>G upstream_gene_variant 0.7 pyrazinamide
panD 4044872 c.-591C>G upstream_gene_variant 0.69 pyrazinamide
panD 4044890 c.-609G>C upstream_gene_variant 0.64 pyrazinamide
panD 4044895 c.-614A>G upstream_gene_variant 0.65 pyrazinamide
panD 4044896 c.-615T>G upstream_gene_variant 0.65 pyrazinamide
panD 4044902 c.-623_-621delACGinsGCC upstream_gene_variant 0.63 pyrazinamide
panD 4044908 c.-628_-627delCTinsTC upstream_gene_variant 0.61 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 0.67 pyrazinamide
panD 4044926 c.-645C>A upstream_gene_variant 0.67 pyrazinamide
panD 4044929 c.-648G>C upstream_gene_variant 0.67 pyrazinamide
panD 4044935 c.-655_-654delAAinsTG upstream_gene_variant 0.67 pyrazinamide
panD 4044941 c.-660G>C upstream_gene_variant 0.68 pyrazinamide
panD 4044954 c.-674_-673delCCinsAT upstream_gene_variant 0.73 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.72 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 0.73 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.73 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.71 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.7 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 0.69 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.68 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.68 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.68 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.67 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.62 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.63 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.63 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.63 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 0.59 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.58 pyrazinamide
panD 4045105 c.-824T>C upstream_gene_variant 0.57 pyrazinamide
panD 4045112 c.-831A>G upstream_gene_variant 0.52 pyrazinamide
panD 4045115 c.-834G>C upstream_gene_variant 0.51 pyrazinamide
panD 4045125 c.-844T>A upstream_gene_variant 0.43 pyrazinamide
panD 4045127 c.-846A>C upstream_gene_variant 0.43 pyrazinamide
panD 4045133 c.-852A>C upstream_gene_variant 0.38 pyrazinamide
panD 4045139 c.-858T>C upstream_gene_variant 0.35 pyrazinamide
panD 4045145 c.-864T>C upstream_gene_variant 0.28 pyrazinamide
panD 4045150 c.-869G>A upstream_gene_variant 0.23 pyrazinamide
glpK 4138409 c.1347G>T synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138418 c.1338T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138424 c.1332T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138429 c.1327T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138451 c.1305T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138460 c.1296C>T synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138472 c.1284G>T synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138475 c.1281C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138478 c.1278T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138490 c.1266G>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138495 p.Gln421Glu missense_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138496 c.1260G>T synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138502 c.1254T>G synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138511 c.1245C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138514 c.1242A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138517 p.Glu413Ala missense_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138523 c.1233C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138529 c.1227G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138535 c.1221T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138565 c.1191G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138568 c.1188A>C synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138571 c.1185C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138574 c.1182G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138580 c.1176C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138598 c.1158G>A synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138601 c.1155G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138610 c.1146C>G synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138622 c.1134C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138625 c.1131G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>A synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138643 c.1113A>C synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138646 c.1110G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138654 c.1102C>T synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 0.67 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138695 p.Pro354Asp missense_variant 0.66 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138721 c.1035G>A synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.7 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138763 c.993G>A synonymous_variant 0.69 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138769 c.987G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138774 p.Ser328Ala missense_variant 0.65 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138778 c.978C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138796 c.960A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138802 c.954G>A synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138808 c.948G>T synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138817 c.939T>C synonymous_variant 0.61 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138822 p.Asn312Asp missense_variant 0.59 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138829 c.927A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138838 c.918G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138841 c.915G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138847 c.909A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138853 c.903C>G synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138859 p.Asn299Asp missense_variant 0.51 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138862 c.894G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138865 c.891A>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138877 c.879A>G synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138880 c.876T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138892 c.864G>A synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138898 c.858T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138910 c.846G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139183 c.561_573delGCCGCGGGGGGGTinsTCCGCGGGGCGGC synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139207 c.549T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139231 c.525A>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139243 c.513A>G synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4240060 c.198G>C synonymous_variant 0.29 ethambutol
embC 4240065 p.Ala68Gly missense_variant 0.3 ethambutol
embC 4240069 c.207T>C synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embC 4240078 c.216A>G synonymous_variant 0.39 ethambutol
embC 4240081 c.219G>C synonymous_variant 0.43 ethambutol
embC 4240087 c.225T>C synonymous_variant 0.43 ethambutol
embC 4240090 c.228C>T synonymous_variant 0.43 ethambutol
embC 4240105 c.243C>T synonymous_variant 0.4 ethambutol
embC 4240123 c.261C>G synonymous_variant 0.41 ethambutol
embC 4240126 c.264C>T synonymous_variant 0.4 ethambutol
embC 4240141 c.279A>G synonymous_variant 0.32 ethambutol
embC 4240145 p.Ala95Thr missense_variant 0.32 ethambutol Uncertain significance
embC 4240149 c.288_289delAT frameshift_variant 0.32 ethambutol
embC 4240154 p.Gln98Gly missense_variant 0.3 ethambutol
embC 4240157 c.295_298delAACAinsGTAACG frameshift_variant&missense_variant 0.31 ethambutol
embC 4240178 c.316T>C synonymous_variant 0.52 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.55 ethambutol
embC 4240204 c.342T>C synonymous_variant 0.52 ethambutol Not assoc w R - Interim
embC 4240216 c.354T>C synonymous_variant 0.45 ethambutol
embC 4240219 c.357C>G synonymous_variant 0.43 ethambutol
embC 4240222 c.360G>C synonymous_variant 0.43 ethambutol
embC 4240229 p.Leu123Ile missense_variant 0.43 ethambutol
embC 4240232 p.Gln124Val missense_variant 0.42 ethambutol
embC 4240249 p.Asp129Glu missense_variant 0.44 ethambutol
embC 4240258 c.396T>G synonymous_variant 0.42 ethambutol
embC 4240267 c.405T>C synonymous_variant 0.43 ethambutol
embC 4240270 c.408T>C synonymous_variant 0.43 ethambutol
embC 4240277 p.Leu139Val missense_variant 0.43 ethambutol
embC 4240282 c.420C>G synonymous_variant 0.43 ethambutol
embC 4240284 p.Thr141Ser missense_variant 0.45 ethambutol
embC 4240288 c.426C>G synonymous_variant 0.45 ethambutol
embC 4240297 c.435T>C synonymous_variant 0.44 ethambutol
embC 4240313 p.Thr151Ala missense_variant 0.39 ethambutol
embC 4240318 c.456T>C synonymous_variant 0.33 ethambutol
embC 4240325 c.463T>C synonymous_variant 0.22 ethambutol
embC 4240484 p.Ala208Thr missense_variant 0.26 ethambutol
embC 4240489 c.627A>G synonymous_variant 0.28 ethambutol
embC 4240492 c.630G>C synonymous_variant 0.28 ethambutol
embC 4240495 c.633T>G synonymous_variant 0.31 ethambutol
embC 4240505 p.Ser215Ala missense_variant 0.4 ethambutol Uncertain significance
embC 4240512 p.Ser217Thr missense_variant 0.4 ethambutol
embC 4240516 c.654G>C synonymous_variant 0.42 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.44 ethambutol
embC 4240543 c.681G>C synonymous_variant 0.57 ethambutol
embC 4240558 c.696C>G synonymous_variant 0.58 ethambutol
embC 4240561 c.699C>G synonymous_variant 0.58 ethambutol
embC 4240570 c.708C>G synonymous_variant 0.58 ethambutol
embC 4240574 p.Val238Leu missense_variant 0.58 ethambutol
embC 4240578 p.Ala239Val missense_variant 0.58 ethambutol
embC 4240582 c.720C>G synonymous_variant 0.6 ethambutol
embC 4240587 p.Gly242Ala missense_variant 0.6 ethambutol
embC 4240592 p.Ala244Ser missense_variant 0.61 ethambutol
embC 4240600 c.738G>C synonymous_variant 0.64 ethambutol
embC 4240610 p.Ile250Arg missense_variant 0.64 ethambutol
embC 4240615 c.753G>C synonymous_variant 0.64 ethambutol
embC 4240632 p.Met257Thr missense_variant 0.63 ethambutol
embC 4240642 c.780G>C synonymous_variant 0.67 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.68 ethambutol
embC 4240669 c.807G>C synonymous_variant 0.67 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.66 ethambutol Not assoc w R
embC 4240677 p.Gly272Ala missense_variant 0.66 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.71 ethambutol
embC 4240693 c.831T>G synonymous_variant 0.7 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.7 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.73 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.73 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.73 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.77 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.75 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.74 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.65 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.62 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.62 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.59 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.59 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.6 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.6 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTTG synonymous_variant 0.58 ethambutol
embC 4240903 c.1041C>G synonymous_variant 0.59 ethambutol
embC 4240909 c.1047G>C synonymous_variant 0.59 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.59 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.57 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.58 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.57 ethambutol
embC 4240945 c.1083T>G synonymous_variant 0.54 ethambutol
embC 4240954 p.Ile364Met missense_variant 0.49 ethambutol
embC 4240960 c.1098G>C synonymous_variant 0.41 ethambutol
embC 4240966 c.1104G>C synonymous_variant 0.34 ethambutol
embC 4240969 c.1107C>T synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embC 4240972 c.1110C>G synonymous_variant 0.29 ethambutol
embC 4240980 p.Thr373Lys missense_variant 0.24 ethambutol
embC 4240987 c.1125G>C synonymous_variant 0.32 ethambutol
embC 4240990 c.1128A>G synonymous_variant 0.37 ethambutol
embC 4240996 c.1134G>C synonymous_variant 0.42 ethambutol
embC 4241002 c.1140G>C synonymous_variant 0.48 ethambutol
embC 4241013 p.Met384Thr missense_variant 0.57 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.57 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.58 ethambutol
embC 4241032 c.1170G>C synonymous_variant 0.6 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.63 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.66 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.67 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.67 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.74 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.74 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.74 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.75 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.73 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.72 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.7 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.69 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.64 ethambutol
embC 4241206 c.1344G>C synonymous_variant 0.61 ethambutol Not assoc w R - Interim
embC 4241218 c.1356G>C synonymous_variant 0.53 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.37 ethambutol
embC 4241233 c.1371G>C synonymous_variant 0.33 ethambutol
embC 4241301 p.Ala480Val missense_variant 0.29 ethambutol Uncertain significance
embC 4241314 c.1452G>C synonymous_variant 0.31 ethambutol
embC 4241319 p.Pro486Leu missense_variant 0.3 ethambutol
embC 4241326 c.1464T>C synonymous_variant 0.27 ethambutol
embC 4241344 c.1482G>C synonymous_variant 0.29 ethambutol
embC 4241351 p.Ile497Val missense_variant 0.32 ethambutol
embC 4241361 p.Asn500Thr missense_variant 0.33 ethambutol
embC 4241363 p.Leu501Met missense_variant 0.33 ethambutol
embC 4241374 c.1512T>C synonymous_variant 0.4 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.46 ethambutol
embC 4241383 c.1521G>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embC 4241394 p.Lys511Ser missense_variant 0.55 ethambutol
embC 4241412 p.Ile517Thr missense_variant 0.65 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.7 ethambutol
embC 4241453 p.Ile531Val missense_variant 0.69 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.74 ethambutol
embC 4241480 c.1618T>C synonymous_variant 0.74 ethambutol
embC 4241488 c.1626G>C synonymous_variant 0.75 ethambutol
embC 4241494 c.1632C>G synonymous_variant 0.74 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.73 ethambutol
embC 4241500 c.1638A>C synonymous_variant 0.72 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.72 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.71 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.71 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.71 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>G synonymous_variant 0.67 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.66 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.66 ethambutol Not assoc w R - Interim
embC 4241545 c.1683T>C synonymous_variant 0.65 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.64 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.64 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.6 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.59 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.53 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.49 ethambutol
embC 4241591 p.Leu577Val missense_variant 0.52 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.44 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.43 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.42 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.43 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.39 ethambutol
embC 4241648 c.1786_1788delTTGinsCTC synonymous_variant 0.44 ethambutol
embC 4241657 p.Ser599Pro missense_variant 0.45 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.42 ethambutol
embC 4241671 c.1809T>C synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embC 4241689 c.1827G>C synonymous_variant 0.41 ethambutol
embC 4241691 p.Gly610Ala missense_variant 0.38 ethambutol Uncertain significance
embC 4241694 p.Ala611Val missense_variant 0.38 ethambutol
embC 4241698 c.1836G>C synonymous_variant 0.38 ethambutol
embC 4241704 c.1842C>G synonymous_variant 0.38 ethambutol
embC 4241713 c.1851G>C synonymous_variant 0.39 ethambutol
embC 4241719 c.1857G>C synonymous_variant 0.39 ethambutol
embC 4241727 p.Phe622Tyr missense_variant 0.38 ethambutol
embC 4241741 p.Val627Leu missense_variant 0.29 ethambutol
embC 4241747 p.Val629Leu missense_variant 0.29 ethambutol
embC 4241750 p.Leu630Val missense_variant 0.3 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.3 ethambutol
embC 4241995 c.2133C>G synonymous_variant 0.3 ethambutol
embC 4242002 p.Leu714Val missense_variant 0.3 ethambutol
embC 4242007 c.2145G>A synonymous_variant 0.3 ethambutol
embC 4242011 p.Leu717Val missense_variant 0.3 ethambutol
embC 4242024 p.Val721Ala missense_variant 0.28 ethambutol
embC 4242036 p.Gln725Leu missense_variant 0.3 ethambutol
embC 4242045 p.Ile728Thr missense_variant 0.3 ethambutol
embC 4242047 p.Ser729Asp missense_variant 0.3 ethambutol
embC 4242055 c.2193C>T synonymous_variant 0.31 ethambutol
embC 4242061 c.2199G>C synonymous_variant 0.33 ethambutol
embC 4242070 c.2208T>C synonymous_variant 0.31 ethambutol
embC 4242076 c.2214G>C synonymous_variant 0.31 ethambutol
embC 4242079 c.2217T>C synonymous_variant 0.32 ethambutol
embC 4242085 c.2223A>G synonymous_variant 0.32 ethambutol
embC 4242091 c.2229T>G synonymous_variant 0.31 ethambutol
embC 4242092 c.2230T>C synonymous_variant 0.31 ethambutol
embC 4242095 p.Ala745Thr missense_variant 0.33 ethambutol Uncertain significance
embC 4242106 c.2244C>G synonymous_variant 0.37 ethambutol
embC 4242121 c.2259A>G synonymous_variant 0.35 ethambutol
embC 4242138 p.Leu759Gln missense_variant 0.26 ethambutol
embC 4242161 p.Ala767Ser missense_variant 0.25 ethambutol
embC 4242170 p.Thr770Gly missense_variant 0.26 ethambutol
embC 4242176 p.Pro772Ser missense_variant 0.26 ethambutol Uncertain significance
embC 4242179 p.Leu773Val missense_variant 0.26 ethambutol
embC 4242193 c.2331G>C synonymous_variant 0.27 ethambutol
embC 4242196 c.2334A>C synonymous_variant 0.27 ethambutol
embC 4242208 c.2346T>G synonymous_variant 0.26 ethambutol
embC 4242220 c.2358A>G synonymous_variant 0.26 ethambutol
embC 4242229 c.2367C>A synonymous_variant 0.27 ethambutol
embC 4242552 p.Arg897Gln missense_variant 0.22 ethambutol
embC 4242629 p.Ala923Ser missense_variant 0.23 ethambutol
embC 4242643 c.2781C>T synonymous_variant 0.76 ethambutol Not assoc w R
embA 4242691 c.-542C>T upstream_gene_variant 0.22 ethambutol
embC 4242710 p.Gln950Glu missense_variant 0.38 ethambutol
embC 4242715 c.2853T>C synonymous_variant 0.42 ethambutol Not assoc w R - Interim
embA 4242742 c.-491C>G upstream_gene_variant 0.58 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.6 ethambutol
embA 4242754 c.-479G>C upstream_gene_variant 0.62 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.65 ethambutol
embA 4242772 c.-461G>C upstream_gene_variant 0.67 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.66 ethambutol
embC 4242791 p.Ala977Ser missense_variant 0.66 ethambutol
embA 4242796 c.-437G>C upstream_gene_variant 0.66 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.65 ethambutol
embA 4242802 c.-431G>C upstream_gene_variant 0.66 ethambutol
embA 4242820 c.-413G>C upstream_gene_variant 0.67 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.68 ethambutol
embA 4242832 c.-401A>C upstream_gene_variant 0.69 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.67 ethambutol
embC 4242841 c.2979C>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embA 4242844 c.-389A>G upstream_gene_variant 0.64 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.65 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.61 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 0.6 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.61 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embA 4242892 c.-341G>C upstream_gene_variant 0.5 ethambutol
embA 4242901 c.-332G>C upstream_gene_variant 0.46 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.32 ethambutol
embC 4242941 p.His1027Asn missense_variant 0.22 ethambutol
embA 4244447 c.1215G>C synonymous_variant 0.35 ethambutol Not assoc w R - Interim
embA 4244462 c.1230A>G synonymous_variant 0.52 ethambutol
embA 4244478 p.Thr416Leu missense_variant 0.55 ethambutol
embA 4244483 c.1251T>G synonymous_variant 0.55 ethambutol
embA 4244485 p.Thr418Ser missense_variant 0.54 ethambutol
embA 4244498 c.1266A>G synonymous_variant 0.53 ethambutol
embA 4244507 c.1275G>T synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embA 4244508 c.1276T>C synonymous_variant 0.54 ethambutol
embA 4244516 c.1284G>C synonymous_variant 0.53 ethambutol
embA 4244517 p.Leu429Val missense_variant 0.54 ethambutol
embA 4244523 p.Pro431Ala missense_variant 0.61 ethambutol
embA 4244534 c.1302T>C synonymous_variant 0.62 ethambutol
embA 4244537 c.1305T>G synonymous_variant 0.62 ethambutol
embA 4244543 c.1311C>G synonymous_variant 0.62 ethambutol
embA 4244547 p.Ile439Val missense_variant 0.63 ethambutol
embA 4244557 p.Arg442Thr missense_variant 0.65 ethambutol
embA 4244582 c.1350T>C synonymous_variant 0.67 ethambutol
embA 4244585 c.1353A>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embA 4244611 p.Ala460Gly missense_variant 0.62 ethambutol
embA 4244616 p.Ala462Ser missense_variant 0.61 ethambutol
embA 4244619 c.1387_1389delTTGinsCTC synonymous_variant 0.59 ethambutol
embA 4244625 p.Leu465Val missense_variant 0.58 ethambutol
embA 4244631 p.Thr467Leu missense_variant 0.58 ethambutol
embA 4244645 c.1413T>C synonymous_variant 0.54 ethambutol
embA 4244648 c.1416G>C synonymous_variant 0.53 ethambutol
embA 4244649 p.Asp473Ser missense_variant 0.53 ethambutol
embA 4244670 p.Ala480Leu missense_variant 0.39 ethambutol
embA 4244675 c.1443A>G synonymous_variant 0.41 ethambutol
embA 4244678 c.1446G>C synonymous_variant 0.41 ethambutol
embA 4244681 c.1449A>C synonymous_variant 0.41 ethambutol
embA 4244690 c.1458G>A synonymous_variant 0.42 ethambutol Not assoc w R - Interim
embA 4244702 c.1470C>G synonymous_variant 0.39 ethambutol
embA 4244708 c.1476C>G synonymous_variant 0.37 ethambutol
embA 4245041 c.1809C>G synonymous_variant 0.3 ethambutol
embA 4245044 c.1812G>C synonymous_variant 0.32 ethambutol
embA 4245053 c.1821G>C synonymous_variant 0.42 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.49 ethambutol
embA 4245083 c.1851A>C synonymous_variant 0.6 ethambutol
embA 4245089 c.1857G>C synonymous_variant 0.62 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.68 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.74 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.76 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.76 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.75 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.76 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.75 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.74 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.73 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.72 ethambutol
embA 4245222 p.Tyr664Gln missense_variant 0.69 ethambutol
embA 4245248 c.2016G>C synonymous_variant 0.7 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.72 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.71 ethambutol Not assoc w R - Interim
embA 4245282 p.Ile684Val missense_variant 0.63 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.63 ethambutol
embA 4245290 c.2058C>G synonymous_variant 0.63 ethambutol
embA 4245293 c.2061T>G synonymous_variant 0.64 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.63 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.63 ethambutol
embA 4245315 p.Val695Thr missense_variant 0.53 ethambutol
embA 4245328 p.Ala699Val missense_variant 0.56 ethambutol
embA 4245335 c.2103A>G synonymous_variant 0.57 ethambutol
embA 4245340 p.Gly703Ala missense_variant 0.61 ethambutol
embA 4245345 p.Met705Leu missense_variant 0.62 ethambutol
embA 4245348 p.Ala706Thr missense_variant 0.6 ethambutol
embA 4245355 p.Ala708Gly missense_variant 0.62 ethambutol
embA 4245368 c.2136T>C synonymous_variant 0.58 ethambutol
embA 4245377 c.2145T>C synonymous_variant 0.51 ethambutol
embA 4245388 p.Ala719Gly missense_variant 0.45 ethambutol
embA 4245401 c.2169G>C synonymous_variant 0.3 ethambutol
embA 4245402 p.Thr724Ala missense_variant 0.29 ethambutol
embA 4245408 p.Leu726Ile missense_variant 0.27 ethambutol
embA 4245413 c.2181C>T synonymous_variant 0.27 ethambutol
embA 4245414 p.Thr728Ser missense_variant 0.27 ethambutol
embA 4245419 c.2187G>C synonymous_variant 0.28 ethambutol
embA 4245431 c.2199T>C synonymous_variant 0.36 ethambutol Not assoc w R - Interim
embA 4245434 c.2202G>C synonymous_variant 0.36 ethambutol
embA 4245470 c.2238T>C synonymous_variant 0.31 ethambutol
embA 4245473 c.2241C>G synonymous_variant 0.31 ethambutol
embA 4245491 c.2259T>A synonymous_variant 0.25 ethambutol
embA 4245501 p.Ala757Thr missense_variant 0.24 ethambutol
embA 4245535 p.Ser768Asn missense_variant 0.25 ethambutol
embB 4245557 c.-957G>A upstream_gene_variant 0.31 ethambutol
embB 4245575 c.-939C>G upstream_gene_variant 0.28 ethambutol
embA 4245576 p.Lys782Gln missense_variant 0.27 ethambutol
embB 4245593 c.-921C>G upstream_gene_variant 0.3 ethambutol
embA 4245594 p.Ser788Thr missense_variant 0.28 ethambutol
embB 4245605 c.-909G>A upstream_gene_variant 0.29 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 0.37 ethambutol
embA 4245623 c.2391G>C synonymous_variant 0.37 ethambutol Not assoc w R - Interim
embB 4245626 c.-888G>C upstream_gene_variant 0.36 ethambutol
embB 4245629 c.-885C>G upstream_gene_variant 0.36 ethambutol
embB 4245635 c.-879A>G upstream_gene_variant 0.37 ethambutol
embB 4245638 c.-876C>G upstream_gene_variant 0.36 ethambutol
embA 4245643 p.Ala804Val missense_variant 0.34 ethambutol
embA 4245648 p.Ile806Tyr missense_variant 0.35 ethambutol
embA 4245652 p.Thr807Ser missense_variant 0.38 ethambutol
embB 4245659 c.-855C>G upstream_gene_variant 0.46 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.46 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.43 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.38 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.38 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.53 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.54 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.58 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.58 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.58 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.58 ethambutol
embA 4245785 c.2553G>C synonymous_variant 0.66 ethambutol Not assoc w R - Interim
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.66 ethambutol
embB 4245812 c.-702G>C upstream_gene_variant 0.67 ethambutol
embA 4245813 p.Pro861Ala missense_variant 0.67 ethambutol
embA 4245820 p.Ser863Thr missense_variant 0.65 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 0.67 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 0.68 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 0.66 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 0.65 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.65 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.62 ethambutol
embA 4245885 p.Asp885Thr missense_variant 0.46 ethambutol
embA 4245892 p.Ile887Thr missense_variant 0.46 ethambutol Uncertain significance
embA 4245899 c.2667C>G synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embB 4245902 c.-612G>A upstream_gene_variant 0.46 ethambutol
embB 4245905 c.-609C>G upstream_gene_variant 0.44 ethambutol
embB 4245911 c.-603A>G upstream_gene_variant 0.45 ethambutol
embB 4245917 c.-597G>A upstream_gene_variant 0.44 ethambutol
embA 4245930 p.Gly900Arg missense_variant 0.41 ethambutol
embB 4245983 c.-531A>C upstream_gene_variant 0.23 ethambutol
embA 4246041 p.Asp937Asn missense_variant 0.26 ethambutol
embA 4246055 c.2823T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4246064 c.-450T>C upstream_gene_variant 0.49 ethambutol
embA 4246080 p.Pro950Ser missense_variant 0.56 ethambutol
embA 4246088 c.2856A>G synonymous_variant 1.0 ethambutol Not assoc w R
embB 4246097 c.-417C>G upstream_gene_variant 0.6 ethambutol
embA 4246103 c.2871C>G synonymous_variant 0.59 ethambutol Not assoc w R - Interim
embB 4246109 c.-405C>G upstream_gene_variant 0.57 ethambutol
embB 4246115 c.-399T>G upstream_gene_variant 0.54 ethambutol
embA 4246128 p.Ser966Thr missense_variant 0.51 ethambutol
embA 4246138 p.Arg969Gln missense_variant 0.52 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 0.52 ethambutol
embA 4246143 p.Ile971Val missense_variant 0.51 ethambutol
embA 4246151 c.2919A>G synonymous_variant 0.52 ethambutol Not assoc w R - Interim
embA 4246152 p.Ala974Gln missense_variant 0.52 ethambutol
embB 4246157 c.-357A>G upstream_gene_variant 0.53 ethambutol
embA 4246164 c.2932T>C synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embB 4246184 c.-330A>C upstream_gene_variant 0.58 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 0.59 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.6 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.57 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.53 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.49 ethambutol
embA 4246227 p.Ile999Val missense_variant 0.49 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.48 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.55 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.57 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.6 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.61 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.69 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.68 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.68 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.67 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.67 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.64 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.61 ethambutol
embA 4246359 p.Ala1043Ser missense_variant 0.57 ethambutol
embB 4246367 c.-147C>T upstream_gene_variant 0.57 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.58 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.58 ethambutol
embA 4246379 c.3147C>T synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embB 4246400 c.-114G>C upstream_gene_variant 0.46 ethambutol
embA 4246413 p.His1061Phe missense_variant 0.31 ethambutol
embA 4246419 c.3187C>T synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embB 4247355 p.Ala281Val missense_variant 0.26 ethambutol Uncertain significance
embB 4247358 p.Val282Ala missense_variant 0.31 ethambutol Uncertain significance
embB 4247365 c.852A>C synonymous_variant 0.4 ethambutol
embB 4247371 c.858C>G synonymous_variant 0.46 ethambutol
embB 4247375 p.Leu288Val missense_variant 0.48 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.51 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.52 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.56 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.59 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.61 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.69 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.69 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.68 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.69 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.73 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.74 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.77 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.78 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.79 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.81 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.79 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.78 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.76 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.75 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.77 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.74 ethambutol
embB 4247611 c.1098G>T synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4247614 c.1101T>C synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.71 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.68 ethambutol
embB 4247638 c.1125G>T synonymous_variant 0.66 ethambutol
embB 4247646 p.Glu378Ala missense_variant 0.59 ethambutol Not assoc w R
embB 4247656 c.1143A>G synonymous_variant 0.57 ethambutol
embB 4247659 c.1146C>G synonymous_variant 0.55 ethambutol
embB 4247662 c.1149C>G synonymous_variant 0.51 ethambutol
embB 4247683 c.1170C>G synonymous_variant 0.61 ethambutol
embB 4247692 c.1179C>G synonymous_variant 0.59 ethambutol
embB 4247716 c.1203C>T synonymous_variant 0.56 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.57 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.57 ethambutol
embB 4247729 p.Gly406Pro missense_variant 0.57 ethambutol
embB 4247746 c.1233C>T synonymous_variant 0.63 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.63 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.64 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.65 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.73 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.72 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.73 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.72 ethambutol
embB 4247819 p.Val436Ile missense_variant 0.72 ethambutol Uncertain significance
embB 4247830 c.1317A>G synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.74 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.73 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.73 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.72 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.75 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.73 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.72 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.73 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.74 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.76 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.75 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.74 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.69 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.69 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.69 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.7 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.68 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.68 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.68 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.68 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.66 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.65 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.65 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.65 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.64 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.64 ethambutol
embB 4248145 p.Leu544Phe missense_variant 0.64 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.68 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.68 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.68 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.67 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.68 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 0.72 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.72 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.74 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.72 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.67 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.67 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.67 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.64 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.63 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.63 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.64 ethambutol
embB 4248382 c.1869C>G synonymous_variant 0.62 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.61 ethambutol
embB 4248407 p.Leu632Val missense_variant 0.5 ethambutol
embB 4248410 p.Phe633Leu missense_variant 0.5 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.5 ethambutol
embB 4248425 c.1912T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 0.51 ethambutol
embB 4248432 p.Trp640Phe missense_variant 0.51 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.43 ethambutol
embB 4248472 c.1959T>C synonymous_variant 0.36 ethambutol
embB 4248475 c.1962G>C synonymous_variant 0.36 ethambutol
embB 4248504 p.Asp664Gly missense_variant 0.32 ethambutol Uncertain significance
embB 4248508 c.1995G>A synonymous_variant 0.32 ethambutol Not assoc w R - Interim
embB 4248512 p.Thr667Ser missense_variant 0.29 ethambutol
embB 4249268 p.Asp919Tyr missense_variant 0.33 ethambutol
embB 4249276 c.2763A>G synonymous_variant 0.37 ethambutol
embB 4249277 p.Tyr922Asn missense_variant 0.37 ethambutol
embB 4249282 c.2769A>C synonymous_variant 0.4 ethambutol
embB 4249291 c.2778C>A synonymous_variant 0.35 ethambutol
embB 4249297 c.2784G>C synonymous_variant 0.38 ethambutol
embB 4249312 c.2799C>T synonymous_variant 0.36 ethambutol
embB 4249321 c.2808A>C synonymous_variant 0.36 ethambutol
embB 4249322 p.Ala937Ser missense_variant 0.36 ethambutol
embB 4249325 p.Lys938Asp missense_variant 0.36 ethambutol
embB 4249333 c.2820C>G synonymous_variant 0.35 ethambutol
embB 4249336 c.2823C>G synonymous_variant 0.34 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.34 ethambutol
embB 4249342 c.2829C>G synonymous_variant 0.37 ethambutol
embB 4249348 c.2835G>C synonymous_variant 0.4 ethambutol
embB 4249351 c.2838C>G synonymous_variant 0.43 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.55 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.58 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.6 ethambutol
embB 4249384 c.2871G>T synonymous_variant 0.61 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.54 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.5 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.51 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.52 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.52 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.57 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.64 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.65 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.66 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.56 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.52 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.51 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.51 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.51 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.51 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.55 ethambutol
embB 4249568 p.Ser1019Thr missense_variant 0.54 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.56 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.53 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.52 ethambutol
embB 4249606 c.3093C>A synonymous_variant 0.42 ethambutol
embB 4249609 c.3096T>C synonymous_variant 0.41 ethambutol
embB 4249615 c.3102C>G synonymous_variant 0.41 ethambutol
embB 4249618 c.3105C>G synonymous_variant 0.41 ethambutol
embB 4249624 c.3111C>G synonymous_variant 0.4 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.41 ethambutol
aftB 4267200 p.Trp546Val missense_variant 0.23 ethambutol
aftB 4267214 c.1623A>C synonymous_variant 0.43 ethambutol
aftB 4267241 c.1596G>C synonymous_variant 0.54 ethambutol
aftB 4267244 c.1593T>C synonymous_variant 0.54 ethambutol
aftB 4267256 c.1581C>G synonymous_variant 0.54 ethambutol
aftB 4267262 c.1575T>C synonymous_variant 0.53 ethambutol
aftB 4267266 p.Ala524Gly missense_variant 0.52 ethambutol
aftB 4267268 c.1569T>C synonymous_variant 0.52 ethambutol
aftB 4267274 c.1563G>C synonymous_variant 0.51 ethambutol
aftB 4267289 p.Ala516Gln missense_variant 0.52 ethambutol
aftB 4267292 c.1545C>G synonymous_variant 0.53 ethambutol
aftB 4267297 c.1540T>C synonymous_variant 0.51 ethambutol
aftB 4267301 c.1536C>T synonymous_variant 0.51 ethambutol
aftB 4267304 p.Val511Ala missense_variant 0.51 ethambutol
aftB 4267316 c.1521A>G synonymous_variant 0.52 ethambutol
aftB 4267325 c.1512G>C synonymous_variant 0.53 ethambutol
aftB 4267334 c.1503T>C synonymous_variant 0.51 ethambutol Not assoc w R - Interim
aftB 4267355 p.Leu494Val missense_variant 0.32 ethambutol
aftB 4267364 p.Met491Leu missense_variant 0.28 ethambutol
aftB 4267571 c.1266T>C synonymous_variant 0.33 ethambutol
aftB 4267574 c.1263G>A synonymous_variant 0.33 ethambutol
aftB 4267580 c.1257G>T synonymous_variant 0.35 ethambutol
aftB 4267647 p.Asp397Gly missense_variant 0.85 ethambutol Not assoc w R
aftB 4268066 p.Val257Leu missense_variant 0.27 ethambutol
aftB 4268081 c.756A>G synonymous_variant 0.49 ethambutol
aftB 4268084 c.753G>C synonymous_variant 0.52 ethambutol
aftB 4268096 c.741C>G synonymous_variant 0.58 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.57 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.57 ethambutol Not assoc w R - Interim
aftB 4268117 c.720G>C synonymous_variant 0.61 ethambutol
aftB 4268123 p.Ser238Gly missense_variant 0.62 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.6 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.63 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.62 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.6 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.61 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.61 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
aftB 4268182 p.Phe219Leu missense_variant 0.58 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.58 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.58 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.55 ethambutol
aftB 4268213 c.624T>G synonymous_variant 0.55 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.47 ethambutol
aftB 4268236 c.601T>C synonymous_variant 0.3 ethambutol
ubiA 4268928 c.906C>T synonymous_variant 0.23 ethambutol Not assoc w R
aftB 4268940 c.-104T>C upstream_gene_variant 0.3 ethambutol
aftB 4268946 c.-110G>A upstream_gene_variant 0.29 ethambutol
ubiA 4268951 p.Val295Ile missense_variant 0.3 ethambutol
aftB 4268952 c.-116G>C upstream_gene_variant 0.29 ethambutol
aftB 4268958 c.-122A>C upstream_gene_variant 0.33 ethambutol
ubiA 4268969 p.Leu289Val missense_variant 0.33 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 0.31 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 0.31 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.31 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.31 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.3 ethambutol
ubiA 4269027 c.807C>T synonymous_variant 0.32 ethambutol Not assoc w R - Interim
aftB 4269033 c.-197T>C upstream_gene_variant 0.33 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.34 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.34 ethambutol
ubiA 4269075 p.Ile253Val missense_variant 0.31 ethambutol
ubiA 4269131 c.703C>T synonymous_variant 0.25 ethambutol Not assoc w R - Interim
aftB 4269138 c.-302C>T upstream_gene_variant 0.25 ethambutol
aftB 4269159 c.-323G>C upstream_gene_variant 0.3 ethambutol
ubiA 4269164 p.Leu224Met missense_variant 0.29 ethambutol
aftB 4269165 c.-329G>C upstream_gene_variant 0.29 ethambutol
aftB 4269179 c.-343C>A upstream_gene_variant 0.29 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.29 ethambutol
aftB 4269186 c.-350C>G upstream_gene_variant 0.28 ethambutol
aftB 4269249 c.-413G>A upstream_gene_variant 0.26 ethambutol
aftB 4269342 c.-506G>C upstream_gene_variant 0.29 ethambutol
ubiA 4269357 p.Ile159Leu missense_variant 0.29 ethambutol
aftB 4269362 c.-526T>C upstream_gene_variant 0.29 ethambutol
aftB 4269363 c.-527T>C upstream_gene_variant 0.29 ethambutol
aftB 4269372 c.-536G>A upstream_gene_variant 0.29 ethambutol
ubiA 4269380 p.Val152Ile missense_variant 0.3 ethambutol
ubiA 4269387 p.Glu149Asp missense_variant 0.28 ethambutol Not assoc w R
aftB 4269390 c.-554G>T upstream_gene_variant 0.25 ethambutol
aftB 4269411 c.-575T>A upstream_gene_variant 0.28 ethambutol
aftB 4269414 c.-578T>C upstream_gene_variant 0.32 ethambutol
aftB 4269420 c.-584T>C upstream_gene_variant 0.39 ethambutol
aftB 4269428 c.-592T>C upstream_gene_variant 0.45 ethambutol
ubiA 4269436 p.Ala133Gly missense_variant 0.48 ethambutol
ubiA 4269448 p.Val129Ala missense_variant 0.51 ethambutol
aftB 4269453 c.-617A>G upstream_gene_variant 0.51 ethambutol
aftB 4269458 c.-622C>T upstream_gene_variant 0.51 ethambutol
aftB 4269459 c.-623G>C upstream_gene_variant 0.52 ethambutol
aftB 4269471 c.-635C>G upstream_gene_variant 0.48 ethambutol
ubiA 4269476 p.Leu120Val missense_variant 0.49 ethambutol
ubiA 4269486 p.Gly116Ile missense_variant 0.44 ethambutol
ubiA 4269490 p.Ala115Gly missense_variant 0.45 ethambutol
ubiA 4269498 p.Thr112Ala missense_variant 0.48 ethambutol
ubiA 4269502 p.Val111Ala missense_variant 0.46 ethambutol
aftB 4269504 c.-668A>T upstream_gene_variant 0.48 ethambutol
ubiA 4269510 p.Val108Leu missense_variant 0.48 ethambutol
ubiA 4269521 p.Val105Leu missense_variant 0.55 ethambutol
ubiA 4269524 p.Thr104Ala missense_variant 0.56 ethambutol Uncertain significance
aftB 4269528 c.-692G>C upstream_gene_variant 0.55 ethambutol
ubiA 4269552 c.282C>G synonymous_variant 0.52 ethambutol Not assoc w R - Interim
aftB 4269555 c.-719C>G upstream_gene_variant 0.53 ethambutol
aftB 4269564 c.-728G>C upstream_gene_variant 0.49 ethambutol
aftB 4269573 c.-737A>G upstream_gene_variant 0.41 ethambutol
ubiA 4269585 c.249G>A synonymous_variant 0.33 ethambutol Not assoc w R - Interim
aftB 4269588 c.-752G>C upstream_gene_variant 0.33 ethambutol
aftB 4269594 c.-758A>C upstream_gene_variant 0.31 ethambutol
ubiA 4269606 c.228T>C synonymous_variant 0.29 ethambutol Not assoc w R
aftB 4269612 c.-776T>C upstream_gene_variant 0.29 ethambutol
aftB 4269621 c.-785C>G upstream_gene_variant 0.29 ethambutol
ubiA 4269624 c.210C>T synonymous_variant 0.28 ethambutol Not assoc w R - Interim
ubiA 4269627 p.Val69Ile missense_variant 0.28 ethambutol
ubiA 4269632 p.Ala68Ser missense_variant 0.27 ethambutol
aftB 4269636 c.-800C>G upstream_gene_variant 0.26 ethambutol
aftB 4269639 c.-803C>G upstream_gene_variant 0.26 ethambutol
ethR 4328190 p.Glu214Asp missense_variant 1.0 ethionamide
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R