TB-Profiler result

Run: ERR3797028

Summary

Run ID: ERR3797028

Sample name:

Date: 2024-04-14T21:09:15.539820

Number of reads: 876703

Percentage reads mapped: 29.62

Median coverage: 41.0

Strain: M.canetti;lineage4.9

Spoligotype:

Drug-resistance: HR-TB


Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.08
lineage4.3.2.1 Euro-American (LAM) RD761 0.06
lineage4 Euro-American None 0.74
lineage1.1.1 Indo-Oceanic RD239 0.07
lineage4.9 Euro-American (H37Rv-like) None 0.87
M.canetti M.canetti None 0.1
lineage4.6.2.1 Euro-American RD726 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.1dupG Assoc w R
c.52_54delCGAinsAG Assoc w R
kanamycin
cycloserine
ethionamide ethA c.1384_1386delCTAinsGG Assoc w R
c.1270_1272delTCAinsGC Assoc w R
c.571_573delGTGinsAC Assoc w R
clofazimine pepQ c.562_564delGTGinsAC Assoc w R - Interim
c.532_534delGCCinsTG Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1018_1020delGGCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1549_1551delCTTinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1963_1965delGGCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2479_2481delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.205_207delCTGinsTA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.358_360delCAGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.352_354delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.391_393delACCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.562_564delGTGinsAC Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.532_534delGCCinsTG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGT frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303948 c.1018_1020delGGCinsCG frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304479 c.1549_1551delCTTinsTG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304893 c.1963_1965delGGCinsAT frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305409 c.2479_2481delGCCinsTG frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
tlyA 1917939 c.1dupG frameshift_variant 0.92 capreomycin Assoc w R
tlyA 1917991 c.52_54delCGAinsAG frameshift_variant&synonymous_variant 0.87 capreomycin Assoc w R
katG 2155107 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.94 isoniazid Assoc w R High-level resistance
pepQ 2859855 c.562_564delGTGinsAC frameshift_variant&missense_variant 1.0 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
pepQ 2859885 c.532_534delGCCinsTG frameshift_variant&missense_variant 1.0 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
fbiA 3640747 c.205_207delCTGinsTA frameshift_variant&stop_gained 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3640900 c.358_360delCAGinsAC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641886 c.352_354delTTAinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641925 c.391_393delACCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
ethA 4326088 c.1384_1386delCTAinsGG frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4326202 c.1270_1272delTCAinsGC frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4326901 c.571_573delGTGinsAC frameshift_variant&missense_variant 0.87 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 24 c.24C>A synonymous_variant 1.0 isoniazid
dnaA 30 c.30C>A synonymous_variant 1.0 isoniazid
dnaA 36 c.36G>T synonymous_variant 1.0 isoniazid
dnaA 42 c.42C>T synonymous_variant 1.0 isoniazid
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 567 c.567C>A synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 576 c.576G>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>C synonymous_variant 0.94 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.94 isoniazid
dnaA 600 c.600T>C synonymous_variant 0.95 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.96 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.96 isoniazid
dnaA 624 c.624C>A synonymous_variant 0.97 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.97 isoniazid
dnaA 630 c.630C>G synonymous_variant 0.97 isoniazid
dnaA 633 c.633T>C synonymous_variant 0.97 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.97 isoniazid
dnaA 663 c.663A>C synonymous_variant 0.96 isoniazid
dnaA 666 c.666C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 682 c.682T>C synonymous_variant 0.96 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.96 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.96 isoniazid
dnaA 702 c.702C>G synonymous_variant 0.97 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.97 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.97 isoniazid
dnaA 714 c.714C>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 810 c.810C>G synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.98 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.98 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.98 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.98 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.98 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.98 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.97 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.97 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.97 isoniazid
dnaA 894 c.894G>A synonymous_variant 0.97 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.97 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.97 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.97 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 930 c.930G>A synonymous_variant 0.95 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.98 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.98 isoniazid
dnaA 975 c.975G>C synonymous_variant 1.0 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 987 c.987C>T synonymous_variant 0.97 isoniazid
dnaA 990 c.990A>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>G synonymous_variant 1.0 isoniazid
dnaA 999 c.999C>G synonymous_variant 1.0 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 0.97 isoniazid
dnaA 1005 c.1005G>T synonymous_variant 0.97 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.97 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.97 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 1.0 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.97 isoniazid
dnaA 1056 c.1056G>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 0.96 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.96 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 1.0 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 1.0 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1126 c.1126C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1137 c.1137C>G synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1177 c.1177_1179delGCGinsTC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1239 c.1239G>C synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1291 c.1291_1293delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1299 c.1299G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 1.0 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 1.0 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1329 c.1329A>G synonymous_variant 1.0 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1335 c.1335G>A synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1350 c.1350G>A synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1362 c.1362C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1369 c.1369_1371delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 1.0 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1485 c.1485A>G synonymous_variant 1.0 isoniazid
gyrB 5282 c.43_45delGCGinsTA frameshift_variant&stop_gained 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5294 c.55_57delATTinsGG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5317 c.78C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5326 c.87T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5329 c.90C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5332 c.93C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5338 c.99C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5347 c.108G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5362 c.123T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6259 p.Asp340Glu missense_variant 0.93 levofloxacin
moxifloxacin
gyrB 6266 p.Pro343Ala missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6316 c.-986G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6346 c.-956C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6385 c.-917G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6592 c.-710C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6766 c.-536G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6772 c.1533C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6794 p.Ile519Leu missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6797 p.Gly520Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6937 c.-365G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6950 c.1711_1713delCTCinsTG frameshift_variant&missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7096 c.-206G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7100 c.1861T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7162 c.-140C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 7190 c.-112C>T upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7382 c.81C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7394 c.93T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7427 c.126G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7619 c.318C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7628 c.327G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7821 c.520C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7880 c.579C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7904 c.603G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 c.618G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8185 p.Lys295Arg missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8195 c.894C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8360 c.1059G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8426 c.1125G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8618 c.1317G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528_1530delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8906 c.1605C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9113 c.1812C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9137 c.1836C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9174 c.1873C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9268 p.Asn656Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9326 c.2025G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9332 c.2031C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9575 c.2274G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9597 c.2296T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9659 c.2358C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9665 c.2364A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9704 c.2403T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9727 p.Gly809Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9729 p.Asp810Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 490803 c.21T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490938 c.156G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491031 c.249C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491280 c.498C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491393 p.Thr204Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491397 p.Glu205Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491400 c.618G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 p.Glu240Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491536 c.754C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
mshA 574659 c.-689A>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574664 c.-684G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574725 c.-623G>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575492 c.145_147delCTGinsGC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575512 c.165A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575516 c.169C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575524 c.177G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575530 c.183C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575545 c.198C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575587 c.240C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575649 p.Val101Ala missense_variant 0.96 ethionamide
isoniazid
mshA 575652 p.Arg102His missense_variant 0.93 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.97 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575674 c.327G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575686 c.339G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575704 c.357T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.97 ethionamide
isoniazid
mshA 575725 c.378C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575728 c.381C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575751 p.Gly135Ala missense_variant 0.95 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.97 ethionamide
isoniazid
mshA 575785 c.438T>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575786 p.Tyr147His missense_variant 0.98 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
mshA 575806 c.459G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575887 c.540G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575899 c.552G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575920 c.573C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576004 c.657T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576011 c.664A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576017 p.Val224Leu missense_variant 1.0 ethionamide
isoniazid
mshA 576045 p.Ala233Gly missense_variant 1.0 ethionamide
isoniazid
mshA 576049 c.702A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576055 c.708C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid
mshA 576061 c.714C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576064 c.717T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576070 c.723T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576073 c.726C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576076 c.729T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576103 c.756G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576106 c.759C>G synonymous_variant 0.93 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGG upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619538 c.-353G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619544 c.-347A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619561 c.-330G>C upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619576 c.-315C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619588 c.-303C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236_-235delATinsGC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619660 c.-231G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619702 c.-189C>T upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619713 c.-178C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619715 c.-176C>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619718 c.-173A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619723 c.-168G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619727 c.-164_-163delACinsGG upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619729 c.-161_-159delACC upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619735 c.-156G>C upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619744 c.-147A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619753 c.-138G>A upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619762 c.-129C>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619766 c.-125A>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619780 c.-111C>T upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619794 c.-97C>A upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619808 c.-83C>T upstream_gene_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620193 c.303C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620223 c.333C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin
ccsA 620246 p.Leu119Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620275 c.385C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>G synonymous_variant 0.97 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620284 p.Ala132Pro missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>T synonymous_variant 0.94 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620412 c.522T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.93 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.96 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620439 c.549T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620449 p.Leu187Met missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620464 p.Ala192Ser missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAG frameshift_variant&missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>G synonymous_variant 0.95 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.93 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620809 c.919C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
Rv0565c 656172 c.1299A>G synonymous_variant 1.0 ethionamide
Rv0565c 656175 p.Glu432Val missense_variant 0.9 ethionamide
Rv0565c 656192 p.Asp427Asn missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656205 p.Ala422Tyr missense_variant 0.93 ethionamide
Rv0565c 656212 p.Arg420His missense_variant 0.93 ethionamide
Rv0565c 656219 p.His418Tyr missense_variant 1.0 ethionamide
Rv0565c 656220 c.1251A>C synonymous_variant 1.0 ethionamide
Rv0565c 656223 c.1248T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656238 c.1233A>G synonymous_variant 1.0 ethionamide
Rv0565c 656244 c.1227A>G synonymous_variant 1.0 ethionamide
Rv0565c 656262 c.1209C>G synonymous_variant 0.88 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 1.0 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 1.0 ethionamide
Rv0565c 656307 c.1164G>C synonymous_variant 0.95 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.94 ethionamide
Rv0565c 656334 c.1137A>G synonymous_variant 0.95 ethionamide
Rv0565c 656346 c.1125G>C synonymous_variant 0.94 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656361 c.1110C>A synonymous_variant 1.0 ethionamide
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656367 c.1104G>C synonymous_variant 1.0 ethionamide
Rv0565c 656370 p.Pro367His missense_variant 1.0 ethionamide
Rv0565c 656373 c.1098C>T synonymous_variant 1.0 ethionamide
Rv0565c 656380 p.Glu364Ala missense_variant 1.0 ethionamide
Rv0565c 656391 c.1078_1080delCTCinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656400 c.1069_1071delGCGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656412 c.1059T>C synonymous_variant 1.0 ethionamide
Rv0565c 656415 c.1056G>C synonymous_variant 1.0 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 1.0 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 1.0 ethionamide
Rv0565c 656436 c.1035C>G synonymous_variant 1.0 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656467 p.Gly335Gln missense_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 1.0 ethionamide
Rv0565c 656472 c.999C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656477 p.Lys332Glu missense_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656503 p.His323Gly missense_variant 1.0 ethionamide
Rv0565c 656505 p.Asp322Glu missense_variant 1.0 ethionamide
Rv0565c 656511 p.His320Arg missense_variant 1.0 ethionamide
Rv0565c 656540 p.Ser311Gly missense_variant 1.0 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 1.0 ethionamide
Rv0565c 656546 p.Ile309Val missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656556 c.915G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656559 c.912C>T synonymous_variant 1.0 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 1.0 ethionamide
Rv0565c 656814 c.657A>G synonymous_variant 1.0 ethionamide
Rv0565c 656820 c.651C>T synonymous_variant 1.0 ethionamide
Rv0565c 656826 c.645C>T synonymous_variant 1.0 ethionamide
Rv0565c 656829 c.642C>G synonymous_variant 1.0 ethionamide
Rv0565c 656835 c.636C>G synonymous_variant 1.0 ethionamide
Rv0565c 656838 c.633A>C synonymous_variant 1.0 ethionamide
Rv0565c 656853 c.618A>G synonymous_variant 1.0 ethionamide
Rv0565c 656865 c.606G>C synonymous_variant 1.0 ethionamide
Rv0565c 656868 p.Asp201Glu missense_variant 1.0 ethionamide
Rv0565c 656871 c.598_600delACCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656880 c.591C>G synonymous_variant 1.0 ethionamide
Rv0565c 656889 c.582A>G synonymous_variant 1.0 ethionamide
Rv0565c 656895 c.576G>C synonymous_variant 1.0 ethionamide
Rv0565c 656898 c.573C>G synonymous_variant 1.0 ethionamide
Rv0565c 656904 c.567G>C synonymous_variant 1.0 ethionamide
Rv0565c 656945 c.526C>T synonymous_variant 1.0 ethionamide
Rv0565c 656952 c.519A>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656973 c.498A>C synonymous_variant 1.0 ethionamide
Rv0565c 656976 c.495G>C synonymous_variant 1.0 ethionamide
Rv0565c 656982 p.Gly163Ala missense_variant 1.0 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656988 p.Lys161Arg missense_variant 1.0 ethionamide
Rv0565c 656991 p.Glu160Asp missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657015 c.456C>T synonymous_variant 1.0 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657056 p.Val139Leu missense_variant 1.0 ethionamide
Rv0565c 657063 c.406_408delAGCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657098 p.Phe125Val missense_variant 1.0 ethionamide
Rv0565c 657105 c.366C>G synonymous_variant 1.0 ethionamide
Rv0565c 657123 c.348A>G synonymous_variant 1.0 ethionamide
Rv0565c 657132 c.339C>T synonymous_variant 1.0 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 1.0 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 1.0 ethionamide
Rv0565c 657187 p.His95Arg missense_variant 1.0 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 1.0 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 1.0 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 1.0 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 1.0 ethionamide
Rv0565c 657207 c.264G>A synonymous_variant 1.0 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 1.0 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 1.0 ethionamide
Rv0565c 657242 p.Glu77Lys missense_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 1.0 ethionamide
Rv0565c 657297 c.174G>T synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 1.0 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 1.0 ethionamide
Rv0565c 657368 c.101_102delAG frameshift_variant 1.0 ethionamide Uncertain significance
Rv0565c 657372 c.98_99insTG frameshift_variant 1.0 ethionamide Uncertain significance
Rv0565c 657381 c.90A>G synonymous_variant 1.0 ethionamide
Rv0565c 657385 p.Ile29Ala missense_variant 1.0 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 1.0 ethionamide
Rv0565c 657405 c.64_66delCTGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657408 c.63A>C synonymous_variant 1.0 ethionamide
Rv0565c 657420 c.51C>G synonymous_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731682 c.-248C>G upstream_gene_variant 1.0 isoniazid
hadA 731687 c.-243G>A upstream_gene_variant 1.0 isoniazid
hadA 731688 c.-242C>T upstream_gene_variant 1.0 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 1.0 isoniazid
hadA 731690 c.-240A>T upstream_gene_variant 1.0 isoniazid
hadA 731694 c.-235_-234delCG upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232_-231insCCTAGAGAGC upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 1.0 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>G upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
hadA 731817 c.-113C>T upstream_gene_variant 1.0 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 732004 c.75T>C synonymous_variant 1.0 isoniazid
hadA 732010 c.81G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732016 c.87C>G synonymous_variant 0.92 isoniazid Not assoc w R - Interim
hadA 732022 c.93C>G synonymous_variant 0.92 isoniazid
hadA 732025 c.96T>G synonymous_variant 0.92 isoniazid
hadA 732029 p.Asn34His missense_variant 0.92 isoniazid
hadA 732038 c.109_111delGCGinsAC frameshift_variant&missense_variant 0.92 isoniazid Uncertain significance
hadA 732045 p.Tyr39Phe missense_variant 0.92 isoniazid
hadA 732060 p.Gly44Ala missense_variant 0.91 isoniazid
hadA 732064 c.135C>G synonymous_variant 0.91 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732112 c.183T>C synonymous_variant 1.0 isoniazid
hadA 732125 p.Lys66Gln missense_variant 1.0 isoniazid
hadA 732190 c.261A>C synonymous_variant 0.9 isoniazid Not assoc w R - Interim
hadA 732196 c.267A>G synonymous_variant 0.91 isoniazid
hadA 732205 c.276A>G synonymous_variant 0.93 isoniazid
hadA 732210 p.Glu94Ala missense_variant 0.93 isoniazid
hadA 732214 c.285A>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
hadA 732223 c.294G>C synonymous_variant 0.95 isoniazid
hadA 732226 c.297G>C synonymous_variant 0.95 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.95 isoniazid
hadA 732252 p.Tyr108Trp missense_variant 0.94 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.94 isoniazid
hadA 732268 c.339T>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
hadA 732272 p.Ala115Ser missense_variant 0.95 isoniazid
hadA 732298 c.369C>G synonymous_variant 0.93 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.96 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 c.400_402delCTCinsGG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 0.97 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.94 isoniazid
hadA 732379 c.450_451delAGinsCGGAA disruptive_inframe_insertion&synonymous_variant 1.0 isoniazid
hadA 732391 c.462T>A synonymous_variant 0.97 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 733856 c.-398T>G upstream_gene_variant 0.9 rifampicin
nusG 733859 c.-395C>G upstream_gene_variant 0.9 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.92 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.93 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.94 rifampicin
nusG 734139 c.-115C>T upstream_gene_variant 0.95 rifampicin Uncertain significance
nusG 734150 c.-104G>C upstream_gene_variant 0.95 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 0.95 rifampicin
nusG 734175 c.-79_-77delGGTinsCTG upstream_gene_variant 1.0 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734193 c.-61A>G upstream_gene_variant 1.0 rifampicin
nusG 734201 c.-53G>C upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 1.0 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 1.0 rifampicin
nusG 734226 c.-28T>C upstream_gene_variant 1.0 rifampicin
nusG 734227 c.-27C>T upstream_gene_variant 1.0 rifampicin
nusG 734232 c.-22G>T upstream_gene_variant 1.0 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734391 c.138C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734394 c.141C>G synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734415 c.162C>G synonymous_variant 1.0 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734457 c.204C>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.98 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.97 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.96 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.97 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.93 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.92 rifampicin
nusG 734637 c.384G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734640 c.387C>G synonymous_variant 0.88 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.92 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.9 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734658 c.405A>G synonymous_variant 0.89 rifampicin Not assoc w R
nusG 734661 c.408A>C synonymous_variant 0.89 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.89 rifampicin
nusG 734670 c.417G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734673 c.420A>G synonymous_variant 0.89 rifampicin
nusG 734676 c.423G>C synonymous_variant 0.89 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734682 c.429C>G synonymous_variant 0.9 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.93 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.92 rifampicin
nusG 734719 p.Ser156Ala missense_variant 0.95 rifampicin
nusG 734722 p.Thr157Ala missense_variant 0.95 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.96 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.96 rifampicin
nusG 734742 c.489T>C synonymous_variant 0.96 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.97 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.96 rifampicin
nusG 734778 c.525G>C synonymous_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734850 c.597C>G synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760088 c.282C>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760124 c.318C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.93 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.94 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.93 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.95 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.93 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.98 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.97 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760521 p.Ser239Ala missense_variant 1.0 rifampicin
rpoB 760528 p.Gln241Arg missense_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.97 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.98 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.84 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760830 c.1024_1026delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760841 c.1035T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.98 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.98 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.98 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.98 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.91 rifampicin
rpoB 761171 c.1365C>G synonymous_variant 0.96 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761301 c.1495C>A synonymous_variant 0.97 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761457 p.Pro551Gly missense_variant 0.98 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>A synonymous_variant 0.98 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.94 rifampicin
rpoB 761720 c.1914_1919delCGAAGAinsGGAG frameshift_variant&synonymous_variant 1.0 rifampicin
rpoB 761728 c.1922_1923insTC frameshift_variant 0.6 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.97 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.97 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.98 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.97 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.98 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.96 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.96 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.97 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.93 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.96 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.97 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.97 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.98 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.98 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.98 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.98 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.97 rifampicin
rpoB 761951 c.2145G>C synonymous_variant 0.98 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.98 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762161 c.2355C>G synonymous_variant 0.96 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>G synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.98 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 0.98 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.98 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.98 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762446 c.-924C>G upstream_gene_variant 1.0 rifampicin
rpoB 762485 c.2679G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 1.0 rifampicin
rpoB 762489 p.Val895Gln missense_variant 1.0 rifampicin
rpoC 762503 c.-867G>C upstream_gene_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762590 c.-780C>G upstream_gene_variant 1.0 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 1.0 rifampicin
rpoB 762599 c.2793T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762605 c.-765T>C upstream_gene_variant 1.0 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 1.0 rifampicin
rpoB 762630 p.Ala942Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 762634 p.Ala943Gly missense_variant 1.0 rifampicin
rpoC 762644 c.-726T>C upstream_gene_variant 1.0 rifampicin
rpoB 762661 p.Arg952Asn missense_variant 1.0 rifampicin
rpoC 762668 c.-702C>G upstream_gene_variant 1.0 rifampicin
rpoB 762671 p.Asp955Glu missense_variant 1.0 rifampicin
rpoB 762674 p.Glu956Asp missense_variant 1.0 rifampicin
rpoC 762680 c.-690C>G upstream_gene_variant 1.0 rifampicin
rpoB 762681 c.2875_2877delGAGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762687 p.Gln961Glu missense_variant 1.0 rifampicin
rpoC 762692 c.-678G>C upstream_gene_variant 1.0 rifampicin
rpoC 762701 c.-669T>C upstream_gene_variant 1.0 rifampicin
rpoC 762728 c.-642C>G upstream_gene_variant 1.0 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 1.0 rifampicin
rpoB 762750 c.2944C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762759 p.Cys985Ala missense_variant 0.97 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762795 p.Asp997Asn missense_variant 0.98 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.98 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762868 p.Tyr1021Phe missense_variant 0.95 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.94 rifampicin
rpoB 763184 c.3378C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 0.95 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763250 c.-120C>T upstream_gene_variant 0.96 rifampicin
rpoC 763253 c.-117G>C upstream_gene_variant 1.0 rifampicin
rpoB 763272 c.3466C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>A synonymous_variant 1.0 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>A synonymous_variant 0.97 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763729 c.360G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763791 p.Glu141Ala missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 0.98 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.98 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 c.507A>G synonymous_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.99 rifampicin
rpoC 763960 c.591T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763963 c.594C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764099 p.Leu244Ile missense_variant 1.0 rifampicin
rpoC 764113 c.744C>T synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764245 c.876C>G synonymous_variant 1.0 rifampicin
rpoC 764248 c.879C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764326 c.957G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764506 c.1137C>T synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>G synonymous_variant 1.0 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764665 c.1296C>G synonymous_variant 1.0 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 1.0 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.98 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.98 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>C synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.96 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765413 p.Pro682Ala missense_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765613 p.His748Gln missense_variant 1.0 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765691 c.2322G>C synonymous_variant 1.0 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365_2367delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>C synonymous_variant 1.0 rifampicin
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>T synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766087 c.2718C>G synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.98 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766489 c.3120G>A synonymous_variant 0.94 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 1.0 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.96 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766627 c.3258G>T synonymous_variant 0.98 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.98 rifampicin
rpoC 766642 c.3273C>T synonymous_variant 0.98 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.98 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.98 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.98 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766795 c.3426C>T synonymous_variant 0.98 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 0.98 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.98 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.98 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.98 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.98 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.98 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.97 rifampicin
rpoC 767152 c.3783T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.98 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767242 p.Gln1291His missense_variant 0.97 rifampicin
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>G synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
mmpL5 775851 p.Ser877Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775853 c.2628C>G synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775862 c.2619G>C synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.9 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775937 c.2542_2544delGCGinsTC frameshift_variant&missense_variant 0.77 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775966 p.Ala839Ser missense_variant 0.69 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775990 c.2491C>T synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2481G>C synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 776017 p.Ile822Val missense_variant 0.93 clofazimine
bedaquiline
mmpL5 776018 c.2463G>C synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 776033 c.2448C>T synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 776039 c.2442C>T synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 776048 c.2433G>A synonymous_variant 0.9 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.95 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781724 c.165G>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>G synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781820 c.261G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.98 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.98 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.98 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.97 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800708 c.-101C>T upstream_gene_variant 0.97 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.96 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 0.95 linezolid
rplC 800808 c.-1A>G upstream_gene_variant 0.95 linezolid
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800826 c.18T>C synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 1.0 linezolid
rplC 800877 c.69A>T synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800967 c.159C>G synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800985 c.177A>C synonymous_variant 1.0 linezolid
rplC 801004 p.Leu66Val missense_variant 1.0 linezolid
rplC 801009 c.201A>C synonymous_variant 1.0 linezolid
rplC 801024 c.216C>G synonymous_variant 0.93 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801030 c.222C>G synonymous_variant 0.93 linezolid
rplC 801039 c.231A>G synonymous_variant 0.93 linezolid
rplC 801045 c.237A>C synonymous_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801136 c.328_329delAGinsTC synonymous_variant 0.93 linezolid
rplC 801141 c.333C>T synonymous_variant 0.94 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801183 c.375C>A synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 0.98 linezolid
rplC 801249 c.441T>G synonymous_variant 0.98 linezolid
rplC 801267 c.459A>C synonymous_variant 0.98 linezolid
rplC 801270 c.462T>C synonymous_variant 0.98 linezolid
rplC 801276 c.468G>C synonymous_variant 0.98 linezolid
rplC 801312 c.504G>C synonymous_variant 0.98 linezolid
rplC 801324 c.516T>C synonymous_variant 0.98 linezolid
rplC 801339 c.531T>C synonymous_variant 0.97 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.97 linezolid
rplC 801348 c.540T>G synonymous_variant 0.97 linezolid
rplC 801349 p.Leu181Val missense_variant 0.97 linezolid
rplC 801357 c.549T>C synonymous_variant 0.97 linezolid
rplC 801360 c.552G>A synonymous_variant 0.97 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.98 linezolid
rplC 801387 c.579G>C synonymous_variant 1.0 linezolid
rplC 801393 c.585G>A synonymous_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801414 c.606C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801417 c.609T>A synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801432 c.624C>G synonymous_variant 1.0 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 1.0 linezolid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303631 p.Pro234Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303776 c.846G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303851 c.921C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303881 c.951G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303914 c.984C>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303923 c.993C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303972 p.Gly348Arg missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304025 c.1095C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304068 p.Val380Ile missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304082 c.1152C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304104 c.1174C>T synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304115 c.1185A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>C synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304161 p.Arg411Ser missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304191 p.Ala421Arg missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304223 c.1293G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304460 c.1530C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304484 c.1554C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304508 p.Glu526Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 p.Asp538Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304547 c.1617C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304616 c.1686C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304682 c.1752C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304778 p.Asp616Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304911 c.1981C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304949 c.2019C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305075 c.2145T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305114 c.2184T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305249 c.2319G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305320 p.Gln797Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305390 c.2460C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305408 c.2478G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305420 c.2490C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305431 p.Val834Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305435 c.2505G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305438 c.2508C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305453 c.2523C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305474 c.2544T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364916 c.504C>G synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 1.0 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 1.0 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365019 c.607C>T synonymous_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 1.0 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 1.0 pyrazinamide
atpE 1460804 c.-241T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460807 c.-238C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460828 c.-217C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460837 c.-208C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1461068 c.24C>T synonymous_variant 1.0 bedaquiline
atpE 1461071 c.27C>A synonymous_variant 1.0 bedaquiline
atpE 1461087 c.43_45delCTGinsAC frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 1.0 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 1.0 bedaquiline
atpE 1461107 c.63C>A synonymous_variant 1.0 bedaquiline