TB-Profiler result

Run: ERR3797028
Summary

Run ID: ERR3797028

Sample name:

Date: 2024-04-14T21:09:15.539820

Number of reads: 876703

Percentage reads mapped: 29.62

Median coverage: 41.0

Strain: M.canetti;lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.08
lineage4.3.2.1 Euro-American (LAM) RD761 0.06
lineage4 Euro-American None 0.74
lineage1.1.1 Indo-Oceanic RD239 0.07
lineage4.9 Euro-American (H37Rv-like) None 0.87
M.canetti M.canetti None 0.1
lineage4.6.2.1 Euro-American RD726 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.1dupG Assoc w R
c.52_54delCGAinsAG Assoc w R
kanamycin
cycloserine
ethionamide ethA c.1384_1386delCTAinsGG Assoc w R
c.1270_1272delTCAinsGC Assoc w R
c.571_573delGTGinsAC Assoc w R
clofazimine pepQ c.562_564delGTGinsAC Assoc w R - Interim
c.532_534delGCCinsTG Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1018_1020delGGCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1549_1551delCTTinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1963_1965delGGCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2479_2481delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.205_207delCTGinsTA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.358_360delCAGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.352_354delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.391_393delACCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.562_564delGTGinsAC Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
c.532_534delGCCinsTG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGT frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303948 c.1018_1020delGGCinsCG frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304479 c.1549_1551delCTTinsTG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304893 c.1963_1965delGGCinsAT frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305409 c.2479_2481delGCCinsTG frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
tlyA 1917939 c.1dupG frameshift_variant 0.92 capreomycin Assoc w R
tlyA 1917991 c.52_54delCGAinsAG frameshift_variant&synonymous_variant 0.87 capreomycin Assoc w R
katG 2155107 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.94 isoniazid Assoc w R High-level resistance
pepQ 2859855 c.562_564delGTGinsAC frameshift_variant&missense_variant 1.0 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
pepQ 2859885 c.532_534delGCCinsTG frameshift_variant&missense_variant 1.0 bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
clofazimine Assoc w R - Interim
fbiA 3640747 c.205_207delCTGinsTA frameshift_variant&stop_gained 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3640900 c.358_360delCAGinsAC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641886 c.352_354delTTAinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641925 c.391_393delACCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
ethA 4326088 c.1384_1386delCTAinsGG frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4326202 c.1270_1272delTCAinsGC frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4326901 c.571_573delGTGinsAC frameshift_variant&missense_variant 0.87 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 24 c.24C>A synonymous_variant 1.0 isoniazid
dnaA 30 c.30C>A synonymous_variant 1.0 isoniazid
dnaA 36 c.36G>T synonymous_variant 1.0 isoniazid
dnaA 42 c.42C>T synonymous_variant 1.0 isoniazid
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 567 c.567C>A synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 576 c.576G>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>C synonymous_variant 0.94 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.94 isoniazid
dnaA 600 c.600T>C synonymous_variant 0.95 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.96 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.96 isoniazid
dnaA 624 c.624C>A synonymous_variant 0.97 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.97 isoniazid
dnaA 630 c.630C>G synonymous_variant 0.97 isoniazid
dnaA 633 c.633T>C synonymous_variant 0.97 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.97 isoniazid
dnaA 663 c.663A>C synonymous_variant 0.96 isoniazid
dnaA 666 c.666C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 682 c.682T>C synonymous_variant 0.96 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.96 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.96 isoniazid
dnaA 702 c.702C>G synonymous_variant 0.97 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.97 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.97 isoniazid
dnaA 714 c.714C>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 810 c.810C>G synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.98 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.98 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.98 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.98 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.98 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.98 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.97 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.97 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.97 isoniazid
dnaA 894 c.894G>A synonymous_variant 0.97 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.97 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.97 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.97 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 930 c.930G>A synonymous_variant 0.95 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.98 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.98 isoniazid
dnaA 975 c.975G>C synonymous_variant 1.0 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 987 c.987C>T synonymous_variant 0.97 isoniazid
dnaA 990 c.990A>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>G synonymous_variant 1.0 isoniazid
dnaA 999 c.999C>G synonymous_variant 1.0 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 0.97 isoniazid
dnaA 1005 c.1005G>T synonymous_variant 0.97 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.97 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.97 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 1.0 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.97 isoniazid
dnaA 1056 c.1056G>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 0.96 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.96 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 1.0 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 1.0 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1126 c.1126C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1137 c.1137C>G synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1177 c.1177_1179delGCGinsTC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1239 c.1239G>C synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1291 c.1291_1293delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1299 c.1299G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 1.0 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 1.0 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1329 c.1329A>G synonymous_variant 1.0 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1335 c.1335G>A synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1350 c.1350G>A synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1362 c.1362C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1369 c.1369_1371delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 1.0 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1485 c.1485A>G synonymous_variant 1.0 isoniazid
gyrB 5282 c.43_45delGCGinsTA frameshift_variant&stop_gained 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5294 c.55_57delATTinsGG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5317 c.78C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5326 c.87T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5329 c.90C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5332 c.93C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5338 c.99C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5347 c.108G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5362 c.123T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6259 p.Asp340Glu missense_variant 0.93 levofloxacin
moxifloxacin
gyrB 6266 p.Pro343Ala missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6316 c.-986G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6346 c.-956C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6385 c.-917G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6592 c.-710C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6766 c.-536G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6772 c.1533C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6794 p.Ile519Leu missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6797 p.Gly520Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6937 c.-365G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6950 c.1711_1713delCTCinsTG frameshift_variant&missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7096 c.-206G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7100 c.1861T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7162 c.-140C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 7190 c.-112C>T upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7382 c.81C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7394 c.93T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7427 c.126G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7619 c.318C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7628 c.327G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7821 c.520C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7880 c.579C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7904 c.603G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 c.618G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8185 p.Lys295Arg missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8195 c.894C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8360 c.1059G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8426 c.1125G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8618 c.1317G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528_1530delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8906 c.1605C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9113 c.1812C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9137 c.1836C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9174 c.1873C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9268 p.Asn656Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9326 c.2025G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9332 c.2031C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9575 c.2274G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9597 c.2296T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9659 c.2358C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9665 c.2364A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9704 c.2403T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9727 p.Gly809Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9729 p.Asp810Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 490803 c.21T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490938 c.156G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491031 c.249C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491280 c.498C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491393 p.Thr204Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491397 p.Glu205Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491400 c.618G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 p.Glu240Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491536 c.754C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
mshA 574659 c.-689A>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574664 c.-684G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574725 c.-623G>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575492 c.145_147delCTGinsGC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575512 c.165A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575516 c.169C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575524 c.177G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575530 c.183C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575545 c.198C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575587 c.240C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575649 p.Val101Ala missense_variant 0.96 ethionamide
isoniazid
mshA 575652 p.Arg102His missense_variant 0.93 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.97 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575674 c.327G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575686 c.339G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575704 c.357T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.97 ethionamide
isoniazid
mshA 575725 c.378C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575728 c.381C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575751 p.Gly135Ala missense_variant 0.95 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.97 ethionamide
isoniazid
mshA 575785 c.438T>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575786 p.Tyr147His missense_variant 0.98 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
mshA 575806 c.459G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575887 c.540G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575899 c.552G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575920 c.573C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576004 c.657T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576011 c.664A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576017 p.Val224Leu missense_variant 1.0 ethionamide
isoniazid
mshA 576045 p.Ala233Gly missense_variant 1.0 ethionamide
isoniazid
mshA 576049 c.702A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576055 c.708C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid
mshA 576061 c.714C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576064 c.717T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576070 c.723T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576073 c.726C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576076 c.729T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576103 c.756G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576106 c.759C>G synonymous_variant 0.93 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGG upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619538 c.-353G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619544 c.-347A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619561 c.-330G>C upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619576 c.-315C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619588 c.-303C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236_-235delATinsGC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619660 c.-231G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619702 c.-189C>T upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619713 c.-178C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619715 c.-176C>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619718 c.-173A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619723 c.-168G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619727 c.-164_-163delACinsGG upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619729 c.-161_-159delACC upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619735 c.-156G>C upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619744 c.-147A>G upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619753 c.-138G>A upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619762 c.-129C>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619766 c.-125A>G upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619780 c.-111C>T upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619794 c.-97C>A upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619808 c.-83C>T upstream_gene_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 620193 c.303C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620223 c.333C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin
ccsA 620246 p.Leu119Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620275 c.385C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>G synonymous_variant 0.97 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620284 p.Ala132Pro missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>T synonymous_variant 0.94 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620412 c.522T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.93 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.96 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620439 c.549T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620449 p.Leu187Met missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620464 p.Ala192Ser missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAG frameshift_variant&missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>G synonymous_variant 0.95 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.93 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620809 c.919C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
Rv0565c 656172 c.1299A>G synonymous_variant 1.0 ethionamide
Rv0565c 656175 p.Glu432Val missense_variant 0.9 ethionamide
Rv0565c 656192 p.Asp427Asn missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656205 p.Ala422Tyr missense_variant 0.93 ethionamide
Rv0565c 656212 p.Arg420His missense_variant 0.93 ethionamide
Rv0565c 656219 p.His418Tyr missense_variant 1.0 ethionamide
Rv0565c 656220 c.1251A>C synonymous_variant 1.0 ethionamide
Rv0565c 656223 c.1248T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656238 c.1233A>G synonymous_variant 1.0 ethionamide
Rv0565c 656244 c.1227A>G synonymous_variant 1.0 ethionamide
Rv0565c 656262 c.1209C>G synonymous_variant 0.88 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 1.0 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 1.0 ethionamide
Rv0565c 656307 c.1164G>C synonymous_variant 0.95 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.94 ethionamide
Rv0565c 656334 c.1137A>G synonymous_variant 0.95 ethionamide
Rv0565c 656346 c.1125G>C synonymous_variant 0.94 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656361 c.1110C>A synonymous_variant 1.0 ethionamide
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656367 c.1104G>C synonymous_variant 1.0 ethionamide
Rv0565c 656370 p.Pro367His missense_variant 1.0 ethionamide
Rv0565c 656373 c.1098C>T synonymous_variant 1.0 ethionamide
Rv0565c 656380 p.Glu364Ala missense_variant 1.0 ethionamide
Rv0565c 656391 c.1078_1080delCTCinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656400 c.1069_1071delGCGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656412 c.1059T>C synonymous_variant 1.0 ethionamide
Rv0565c 656415 c.1056G>C synonymous_variant 1.0 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 1.0 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 1.0 ethionamide
Rv0565c 656436 c.1035C>G synonymous_variant 1.0 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656467 p.Gly335Gln missense_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 1.0 ethionamide
Rv0565c 656472 c.999C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656477 p.Lys332Glu missense_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656503 p.His323Gly missense_variant 1.0 ethionamide
Rv0565c 656505 p.Asp322Glu missense_variant 1.0 ethionamide
Rv0565c 656511 p.His320Arg missense_variant 1.0 ethionamide
Rv0565c 656540 p.Ser311Gly missense_variant 1.0 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 1.0 ethionamide
Rv0565c 656546 p.Ile309Val missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656556 c.915G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656559 c.912C>T synonymous_variant 1.0 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 1.0 ethionamide
Rv0565c 656814 c.657A>G synonymous_variant 1.0 ethionamide
Rv0565c 656820 c.651C>T synonymous_variant 1.0 ethionamide
Rv0565c 656826 c.645C>T synonymous_variant 1.0 ethionamide
Rv0565c 656829 c.642C>G synonymous_variant 1.0 ethionamide
Rv0565c 656835 c.636C>G synonymous_variant 1.0 ethionamide
Rv0565c 656838 c.633A>C synonymous_variant 1.0 ethionamide
Rv0565c 656853 c.618A>G synonymous_variant 1.0 ethionamide
Rv0565c 656865 c.606G>C synonymous_variant 1.0 ethionamide
Rv0565c 656868 p.Asp201Glu missense_variant 1.0 ethionamide
Rv0565c 656871 c.598_600delACCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656880 c.591C>G synonymous_variant 1.0 ethionamide
Rv0565c 656889 c.582A>G synonymous_variant 1.0 ethionamide
Rv0565c 656895 c.576G>C synonymous_variant 1.0 ethionamide
Rv0565c 656898 c.573C>G synonymous_variant 1.0 ethionamide
Rv0565c 656904 c.567G>C synonymous_variant 1.0 ethionamide
Rv0565c 656945 c.526C>T synonymous_variant 1.0 ethionamide
Rv0565c 656952 c.519A>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656973 c.498A>C synonymous_variant 1.0 ethionamide
Rv0565c 656976 c.495G>C synonymous_variant 1.0 ethionamide
Rv0565c 656982 p.Gly163Ala missense_variant 1.0 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656988 p.Lys161Arg missense_variant 1.0 ethionamide
Rv0565c 656991 p.Glu160Asp missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657015 c.456C>T synonymous_variant 1.0 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657056 p.Val139Leu missense_variant 1.0 ethionamide
Rv0565c 657063 c.406_408delAGCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657098 p.Phe125Val missense_variant 1.0 ethionamide
Rv0565c 657105 c.366C>G synonymous_variant 1.0 ethionamide
Rv0565c 657123 c.348A>G synonymous_variant 1.0 ethionamide
Rv0565c 657132 c.339C>T synonymous_variant 1.0 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 1.0 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 1.0 ethionamide
Rv0565c 657187 p.His95Arg missense_variant 1.0 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 1.0 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 1.0 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 1.0 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 1.0 ethionamide
Rv0565c 657207 c.264G>A synonymous_variant 1.0 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 1.0 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 1.0 ethionamide
Rv0565c 657242 p.Glu77Lys missense_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 1.0 ethionamide
Rv0565c 657297 c.174G>T synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 1.0 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 1.0 ethionamide
Rv0565c 657368 c.101_102delAG frameshift_variant 1.0 ethionamide Uncertain significance
Rv0565c 657372 c.98_99insTG frameshift_variant 1.0 ethionamide Uncertain significance
Rv0565c 657381 c.90A>G synonymous_variant 1.0 ethionamide
Rv0565c 657385 p.Ile29Ala missense_variant 1.0 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 1.0 ethionamide
Rv0565c 657405 c.64_66delCTGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657408 c.63A>C synonymous_variant 1.0 ethionamide
Rv0565c 657420 c.51C>G synonymous_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731682 c.-248C>G upstream_gene_variant 1.0 isoniazid
hadA 731687 c.-243G>A upstream_gene_variant 1.0 isoniazid
hadA 731688 c.-242C>T upstream_gene_variant 1.0 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 1.0 isoniazid
hadA 731690 c.-240A>T upstream_gene_variant 1.0 isoniazid
hadA 731694 c.-235_-234delCG upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232_-231insCCTAGAGAGC upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 1.0 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>G upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
hadA 731817 c.-113C>T upstream_gene_variant 1.0 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 732004 c.75T>C synonymous_variant 1.0 isoniazid
hadA 732010 c.81G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732016 c.87C>G synonymous_variant 0.92 isoniazid Not assoc w R - Interim
hadA 732022 c.93C>G synonymous_variant 0.92 isoniazid
hadA 732025 c.96T>G synonymous_variant 0.92 isoniazid
hadA 732029 p.Asn34His missense_variant 0.92 isoniazid
hadA 732038 c.109_111delGCGinsAC frameshift_variant&missense_variant 0.92 isoniazid Uncertain significance
hadA 732045 p.Tyr39Phe missense_variant 0.92 isoniazid
hadA 732060 p.Gly44Ala missense_variant 0.91 isoniazid
hadA 732064 c.135C>G synonymous_variant 0.91 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732112 c.183T>C synonymous_variant 1.0 isoniazid
hadA 732125 p.Lys66Gln missense_variant 1.0 isoniazid
hadA 732190 c.261A>C synonymous_variant 0.9 isoniazid Not assoc w R - Interim
hadA 732196 c.267A>G synonymous_variant 0.91 isoniazid
hadA 732205 c.276A>G synonymous_variant 0.93 isoniazid
hadA 732210 p.Glu94Ala missense_variant 0.93 isoniazid
hadA 732214 c.285A>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
hadA 732223 c.294G>C synonymous_variant 0.95 isoniazid
hadA 732226 c.297G>C synonymous_variant 0.95 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.95 isoniazid
hadA 732252 p.Tyr108Trp missense_variant 0.94 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.94 isoniazid
hadA 732268 c.339T>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
hadA 732272 p.Ala115Ser missense_variant 0.95 isoniazid
hadA 732298 c.369C>G synonymous_variant 0.93 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.96 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 c.400_402delCTCinsGG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 0.97 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.94 isoniazid
hadA 732379 c.450_451delAGinsCGGAA disruptive_inframe_insertion&synonymous_variant 1.0 isoniazid
hadA 732391 c.462T>A synonymous_variant 0.97 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 733856 c.-398T>G upstream_gene_variant 0.9 rifampicin
nusG 733859 c.-395C>G upstream_gene_variant 0.9 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.92 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.93 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.94 rifampicin
nusG 734139 c.-115C>T upstream_gene_variant 0.95 rifampicin Uncertain significance
nusG 734150 c.-104G>C upstream_gene_variant 0.95 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 0.95 rifampicin
nusG 734175 c.-79_-77delGGTinsCTG upstream_gene_variant 1.0 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734193 c.-61A>G upstream_gene_variant 1.0 rifampicin
nusG 734201 c.-53G>C upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 1.0 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 1.0 rifampicin
nusG 734226 c.-28T>C upstream_gene_variant 1.0 rifampicin
nusG 734227 c.-27C>T upstream_gene_variant 1.0 rifampicin
nusG 734232 c.-22G>T upstream_gene_variant 1.0 rifampicin
nusG 734370 c.117A>G synonymous_variant 1.0 rifampicin
nusG 734391 c.138C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734394 c.141C>G synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734415 c.162C>G synonymous_variant 1.0 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734457 c.204C>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.98 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.97 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.96 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.97 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.93 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.92 rifampicin
nusG 734637 c.384G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734640 c.387C>G synonymous_variant 0.88 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.92 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.9 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734658 c.405A>G synonymous_variant 0.89 rifampicin Not assoc w R
nusG 734661 c.408A>C synonymous_variant 0.89 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.89 rifampicin
nusG 734670 c.417G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734673 c.420A>G synonymous_variant 0.89 rifampicin
nusG 734676 c.423G>C synonymous_variant 0.89 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734682 c.429C>G synonymous_variant 0.9 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.93 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.92 rifampicin
nusG 734719 p.Ser156Ala missense_variant 0.95 rifampicin
nusG 734722 p.Thr157Ala missense_variant 0.95 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.96 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.96 rifampicin
nusG 734742 c.489T>C synonymous_variant 0.96 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.97 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.96 rifampicin
nusG 734778 c.525G>C synonymous_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734850 c.597C>G synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760088 c.282C>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760124 c.318C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.93 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.94 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.93 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.95 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.93 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.98 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.97 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760521 p.Ser239Ala missense_variant 1.0 rifampicin
rpoB 760528 p.Gln241Arg missense_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.97 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.98 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.84 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760830 c.1024_1026delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760841 c.1035T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.98 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.98 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.98 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.98 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.91 rifampicin
rpoB 761171 c.1365C>G synonymous_variant 0.96 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761301 c.1495C>A synonymous_variant 0.97 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761457 p.Pro551Gly missense_variant 0.98 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>A synonymous_variant 0.98 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.94 rifampicin
rpoB 761720 c.1914_1919delCGAAGAinsGGAG frameshift_variant&synonymous_variant 1.0 rifampicin
rpoB 761728 c.1922_1923insTC frameshift_variant 0.6 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.97 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.97 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.98 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.97 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.98 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.96 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.96 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.97 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.93 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.96 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.97 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.97 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.98 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.98 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.98 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.98 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.97 rifampicin
rpoB 761951 c.2145G>C synonymous_variant 0.98 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.98 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762161 c.2355C>G synonymous_variant 0.96 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>G synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.98 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 0.98 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.98 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.98 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762446 c.-924C>G upstream_gene_variant 1.0 rifampicin
rpoB 762485 c.2679G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 1.0 rifampicin
rpoB 762489 p.Val895Gln missense_variant 1.0 rifampicin
rpoC 762503 c.-867G>C upstream_gene_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762590 c.-780C>G upstream_gene_variant 1.0 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 1.0 rifampicin
rpoB 762599 c.2793T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762605 c.-765T>C upstream_gene_variant 1.0 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 1.0 rifampicin
rpoB 762630 p.Ala942Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 762634 p.Ala943Gly missense_variant 1.0 rifampicin
rpoC 762644 c.-726T>C upstream_gene_variant 1.0 rifampicin
rpoB 762661 p.Arg952Asn missense_variant 1.0 rifampicin
rpoC 762668 c.-702C>G upstream_gene_variant 1.0 rifampicin
rpoB 762671 p.Asp955Glu missense_variant 1.0 rifampicin
rpoB 762674 p.Glu956Asp missense_variant 1.0 rifampicin
rpoC 762680 c.-690C>G upstream_gene_variant 1.0 rifampicin
rpoB 762681 c.2875_2877delGAGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762687 p.Gln961Glu missense_variant 1.0 rifampicin
rpoC 762692 c.-678G>C upstream_gene_variant 1.0 rifampicin
rpoC 762701 c.-669T>C upstream_gene_variant 1.0 rifampicin
rpoC 762728 c.-642C>G upstream_gene_variant 1.0 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 1.0 rifampicin
rpoB 762750 c.2944C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762759 p.Cys985Ala missense_variant 0.97 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762795 p.Asp997Asn missense_variant 0.98 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.98 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762868 p.Tyr1021Phe missense_variant 0.95 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.94 rifampicin
rpoB 763184 c.3378C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 0.95 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763250 c.-120C>T upstream_gene_variant 0.96 rifampicin
rpoC 763253 c.-117G>C upstream_gene_variant 1.0 rifampicin
rpoB 763272 c.3466C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>A synonymous_variant 1.0 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>A synonymous_variant 0.97 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763729 c.360G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763791 p.Glu141Ala missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 0.98 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.98 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 c.507A>G synonymous_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.99 rifampicin
rpoC 763960 c.591T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763963 c.594C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764099 p.Leu244Ile missense_variant 1.0 rifampicin
rpoC 764113 c.744C>T synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764245 c.876C>G synonymous_variant 1.0 rifampicin
rpoC 764248 c.879C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764326 c.957G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764506 c.1137C>T synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>G synonymous_variant 1.0 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764665 c.1296C>G synonymous_variant 1.0 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 1.0 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.98 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.98 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>C synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.96 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765413 p.Pro682Ala missense_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765613 p.His748Gln missense_variant 1.0 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765691 c.2322G>C synonymous_variant 1.0 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365_2367delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>C synonymous_variant 1.0 rifampicin
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>T synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 1.0 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766087 c.2718C>G synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.98 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766489 c.3120G>A synonymous_variant 0.94 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 1.0 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.96 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766627 c.3258G>T synonymous_variant 0.98 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.98 rifampicin
rpoC 766642 c.3273C>T synonymous_variant 0.98 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.98 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.98 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.98 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766795 c.3426C>T synonymous_variant 0.98 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 0.98 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.98 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.98 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.98 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.98 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.98 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.97 rifampicin
rpoC 767152 c.3783T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.98 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767242 p.Gln1291His missense_variant 0.97 rifampicin
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>G synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
mmpL5 775851 p.Ser877Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775853 c.2628C>G synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775862 c.2619G>C synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.9 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775937 c.2542_2544delGCGinsTC frameshift_variant&missense_variant 0.77 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775966 p.Ala839Ser missense_variant 0.69 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775990 c.2491C>T synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2481G>C synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 776017 p.Ile822Val missense_variant 0.93 clofazimine
bedaquiline
mmpL5 776018 c.2463G>C synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 776033 c.2448C>T synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 776039 c.2442C>T synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 776048 c.2433G>A synonymous_variant 0.9 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.95 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781724 c.165G>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>G synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781820 c.261G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.98 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.98 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.98 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.97 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800708 c.-101C>T upstream_gene_variant 0.97 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.96 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 0.95 linezolid
rplC 800808 c.-1A>G upstream_gene_variant 0.95 linezolid
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800826 c.18T>C synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 1.0 linezolid
rplC 800877 c.69A>T synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800967 c.159C>G synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800985 c.177A>C synonymous_variant 1.0 linezolid
rplC 801004 p.Leu66Val missense_variant 1.0 linezolid
rplC 801009 c.201A>C synonymous_variant 1.0 linezolid
rplC 801024 c.216C>G synonymous_variant 0.93 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801030 c.222C>G synonymous_variant 0.93 linezolid
rplC 801039 c.231A>G synonymous_variant 0.93 linezolid
rplC 801045 c.237A>C synonymous_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801136 c.328_329delAGinsTC synonymous_variant 0.93 linezolid
rplC 801141 c.333C>T synonymous_variant 0.94 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801183 c.375C>A synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 0.98 linezolid
rplC 801249 c.441T>G synonymous_variant 0.98 linezolid
rplC 801267 c.459A>C synonymous_variant 0.98 linezolid
rplC 801270 c.462T>C synonymous_variant 0.98 linezolid
rplC 801276 c.468G>C synonymous_variant 0.98 linezolid
rplC 801312 c.504G>C synonymous_variant 0.98 linezolid
rplC 801324 c.516T>C synonymous_variant 0.98 linezolid
rplC 801339 c.531T>C synonymous_variant 0.97 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.97 linezolid
rplC 801348 c.540T>G synonymous_variant 0.97 linezolid
rplC 801349 p.Leu181Val missense_variant 0.97 linezolid
rplC 801357 c.549T>C synonymous_variant 0.97 linezolid
rplC 801360 c.552G>A synonymous_variant 0.97 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.98 linezolid
rplC 801387 c.579G>C synonymous_variant 1.0 linezolid
rplC 801393 c.585G>A synonymous_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801414 c.606C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801417 c.609T>A synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801432 c.624C>G synonymous_variant 1.0 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 1.0 linezolid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303631 p.Pro234Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303776 c.846G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303851 c.921C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303881 c.951G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303897 c.967C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303914 c.984C>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303923 c.993C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303972 p.Gly348Arg missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304025 c.1095C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304068 p.Val380Ile missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304082 c.1152C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304104 c.1174C>T synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304115 c.1185A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>C synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304161 p.Arg411Ser missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304191 p.Ala421Arg missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304223 c.1293G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304460 c.1530C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304484 c.1554C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304508 p.Glu526Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 p.Asp538Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304547 c.1617C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304616 c.1686C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304682 c.1752C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304778 p.Asp616Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304911 c.1981C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304949 c.2019C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305075 c.2145T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305114 c.2184T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305249 c.2319G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305320 p.Gln797Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305390 c.2460C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305408 c.2478G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305420 c.2490C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305431 p.Val834Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305435 c.2505G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305438 c.2508C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305453 c.2523C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305474 c.2544T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364916 c.504C>G synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 1.0 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 1.0 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365019 c.607C>T synonymous_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 1.0 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 1.0 pyrazinamide
atpE 1460804 c.-241T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460807 c.-238C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460828 c.-217C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460837 c.-208C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1461068 c.24C>T synonymous_variant 1.0 bedaquiline
atpE 1461071 c.27C>A synonymous_variant 1.0 bedaquiline
atpE 1461087 c.43_45delCTGinsAC frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 1.0 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 1.0 bedaquiline
atpE 1461107 c.63C>A synonymous_variant 1.0 bedaquiline
atpE 1461113 c.69C>A synonymous_variant 0.95 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.96 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 0.95 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.94 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.94 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.93 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.92 bedaquiline
rrs 1471508 n.-338T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471514 n.-332A>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445delCinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473417 n.-241C>T upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473419 n.-239T>C upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473667 n.10T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474018 n.361G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475018 n.1361G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475019 n.1362T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475294 n.1637T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475297 n.1640C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475758 n.2104delC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476711 n.3054G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476719 n.3062C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
inhA 1673499 c.-703T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673502 c.-700C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673505 c.-697A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673523 c.-679G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673537 p.Gln33Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673550 c.-652C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673574 c.-628C>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673592 c.-610G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 0.98 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.98 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.95 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.95 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673679 c.-523T>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673706 c.-496C>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.94 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.92 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.95 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.95 ethionamide
isoniazid
fabG1 1673767 p.Asn110Asp missense_variant 0.95 ethionamide
isoniazid
inhA 1673877 c.-325C>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.96 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.96 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673931 c.-271C>G upstream_gene_variant 0.97 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.97 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673949 c.-253G>A upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673961 c.-241A>G upstream_gene_variant 0.97 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 0.97 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673982 c.-220G>C upstream_gene_variant 0.97 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.98 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674042 c.-160G>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674108 c.-94C>T upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674111 c.-91G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674147 c.-55C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674205 p.Thr2Ala missense_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1674216 c.15G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674219 p.Asp6Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674231 c.30T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674237 c.36T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674238 c.37_38delAGinsTC synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674243 c.42A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674279 c.78A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674280 p.Arg27Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674285 c.84A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674294 c.93G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674295 p.Gln32Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674300 c.99C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674303 c.102C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674307 c.106C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674315 c.114C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674321 c.120G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674331 c.130C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674336 c.135G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid
inhA 1674363 c.162G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674368 p.Ala56Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674375 c.174C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674382 p.Leu61Ile missense_variant 1.0 ethionamide
isoniazid
inhA 1674419 p.Ser73Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674421 c.220T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674428 p.Gly76Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674438 c.237C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674440 p.Glu80Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674443 p.Ala81Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674465 c.264C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674504 c.303C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674537 c.336C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674552 c.351C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674567 c.366C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674575 p.Tyr125Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>T synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674738 c.537C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674742 p.Lys181Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674819 c.618G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674939 c.738G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674945 p.Asp248Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833250 c.-292A>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833256 c.-286C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833262 c.-280T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833265 c.-277A>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833268 c.-274C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833541 c.-1T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834170 p.Thr210Ser missense_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834258 c.717G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834459 c.918G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834558 c.1017C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834561 c.1020C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834570 c.1029C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834657 c.1116G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.98 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834753 c.1212T>G synonymous_variant 0.97 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.97 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.97 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.97 pyrazinamide
rpsA 1834775 p.Ala412Asn missense_variant 0.96 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834798 c.1257C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834840 c.1299G>A synonymous_variant 0.93 pyrazinamide
rpsA 1834849 c.1308C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834852 c.1311C>G synonymous_variant 0.91 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTC upstream_gene_variant 0.98 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 0.98 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.98 linezolid
tsnR 1853411 c.-195C>T upstream_gene_variant 0.98 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.98 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.98 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.98 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.98 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.98 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.97 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 0.97 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.97 linezolid
tsnR 1853531 c.-75A>C upstream_gene_variant 0.92 linezolid
tsnR 1853540 c.-66A>C upstream_gene_variant 0.9 linezolid
tsnR 1853968 c.363C>T synonymous_variant 1.0 linezolid
tsnR 1853978 c.373_375delGTAinsCG frameshift_variant&missense_variant 1.0 linezolid Uncertain significance
tsnR 1854004 c.399T>C synonymous_variant 1.0 linezolid
tsnR 1854007 c.402C>G synonymous_variant 1.0 linezolid
tsnR 1854009 p.Ala135Gly missense_variant 1.0 linezolid
tsnR 1854024 p.Ala140Gly missense_variant 1.0 linezolid
tsnR 1854030 p.Arg142His missense_variant 1.0 linezolid
tsnR 1854043 c.438A>G synonymous_variant 1.0 linezolid
tsnR 1854058 c.453T>C synonymous_variant 1.0 linezolid
tsnR 1854067 c.462G>C synonymous_variant 1.0 linezolid
tsnR 1854070 c.465C>G synonymous_variant 1.0 linezolid
tsnR 1854071 c.466_468delACCinsGG frameshift_variant&missense_variant 1.0 linezolid Uncertain significance
tsnR 1854076 c.471T>C synonymous_variant 1.0 linezolid
tsnR 1854086 p.Ala161Ser missense_variant 1.0 linezolid
tlyA 1917900 c.-40T>C upstream_gene_variant 0.9 capreomycin
tlyA 1917929 c.-11T>C upstream_gene_variant 0.92 capreomycin
tlyA 1917938 c.-2G>A upstream_gene_variant 0.92 capreomycin
tlyA 1917945 c.6A>G synonymous_variant 0.93 capreomycin
tlyA 1917960 c.21T>C synonymous_variant 0.87 capreomycin
tlyA 1917972 c.33A>C synonymous_variant 1.0 capreomycin
tlyA 1917978 c.39G>C synonymous_variant 0.87 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.87 capreomycin
tlyA 1917984 c.45C>G synonymous_variant 0.87 capreomycin
tlyA 1917987 c.48G>C synonymous_variant 0.87 capreomycin
tlyA 1917996 c.57A>C synonymous_variant 0.93 capreomycin
tlyA 1918026 c.87C>G synonymous_variant 0.92 capreomycin
bacA 2064882 c.-154C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064916 c.-190_-188delGATinsTG upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064927 c.-199G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064939 c.-211C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064942 c.-214G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064963 c.-235G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064966 c.-238G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064975 c.-247G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101774 c.1269T>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101808 p.Thr412Ser missense_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101812 p.Ile411Val missense_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101819 c.1224G>A synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101830 p.Ile405Val missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101837 p.Ala402Val missense_variant 1.0 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101876 c.1167C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101888 c.1153_1155delGTTinsCG frameshift_variant&missense_variant 0.98 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101891 c.1152C>G synonymous_variant 0.98 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101920 c.1123A>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101966 c.1077T>G synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101969 p.Glu358Asp missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101972 c.1071G>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101980 p.Asn355Asp missense_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101988 p.Ala352Asp missense_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2102007 p.Thr346Ala missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102009 p.Ser345Ala missense_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102011 c.1032C>G synonymous_variant 0.95 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102015 p.Val343Ala missense_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102020 c.1023A>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102023 c.1020G>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102026 c.1017G>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102065 c.978G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102068 c.975T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102077 c.966T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102246 p.Val266Thr missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102249 p.Thr265Ser missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102269 c.774C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102310 c.733C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102314 c.729C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102320 c.723G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102334 p.Gln237Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102337 c.706T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid
ndh 2102341 c.702C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102344 c.699T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102355 p.Gln230Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102356 c.687T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102366 p.Ala226Glu missense_variant 1.0 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102371 c.670_672delATGinsTC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102377 c.666A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102389 c.654G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102401 c.642T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102407 c.636T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102416 c.627G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102653 p.His130Gln missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102668 c.375T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102736 c.307T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102737 p.Glu102Asp missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102750 p.Cys98Phe missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102755 c.288G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102758 p.Ala95Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102773 c.270C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102781 p.Asn88Asp missense_variant 1.0 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102785 c.256_258delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102790 c.253C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102791 c.252A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102800 c.243T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102810 p.Lys78Arg missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102812 c.231T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102830 c.213G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102836 c.207T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102842 p.Glu67Asp missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102845 c.198A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102854 c.187_189delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102857 c.186T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102863 c.180C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102866 c.177C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102872 c.171A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102911 c.132G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
katG 2155080 c.1032G>C synonymous_variant 1.0 isoniazid
katG 2155113 c.999C>G synonymous_variant 1.0 isoniazid
katG 2155119 p.Ser331Thr missense_variant 1.0 isoniazid
katG 2155131 c.981A>G synonymous_variant 0.91 isoniazid Not assoc w R - Interim
katG 2155134 c.978G>C synonymous_variant 0.91 isoniazid
katG 2155581 c.531C>A synonymous_variant 0.91 isoniazid
katG 2155590 c.522A>G synonymous_variant 0.93 isoniazid
katG 2155596 c.516G>C synonymous_variant 0.94 isoniazid
katG 2155617 c.495T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
katG 2155626 c.486G>C synonymous_variant 0.95 isoniazid
katG 2155632 c.480A>C synonymous_variant 0.95 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.95 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.95 isoniazid Uncertain significance
katG 2155670 c.442C>T synonymous_variant 1.0 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>C synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
katG 2155740 p.Gly124Gln missense_variant 1.0 isoniazid
katG 2155743 c.369G>C synonymous_variant 1.0 isoniazid
katG 2155747 p.Ala122Gly missense_variant 1.0 isoniazid
katG 2155764 p.His116Gln missense_variant 1.0 isoniazid
katG 2155767 c.345C>T synonymous_variant 1.0 isoniazid
katG 2155785 c.327T>C synonymous_variant 1.0 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.94 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.94 isoniazid
kasA 2518162 c.48G>A synonymous_variant 1.0 isoniazid
kasA 2518174 c.60A>G synonymous_variant 1.0 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518245 p.His44Arg missense_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518255 c.141A>G synonymous_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 1.0 isoniazid
kasA 2518282 c.168A>G synonymous_variant 1.0 isoniazid
kasA 2518283 c.169_171delGCGinsCC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518297 c.183C>T synonymous_variant 1.0 isoniazid
kasA 2518300 c.186T>A synonymous_variant 1.0 isoniazid
kasA 2518312 p.Asp66Glu missense_variant 1.0 isoniazid
kasA 2518315 c.201G>C synonymous_variant 1.0 isoniazid
kasA 2518323 p.Ser70Asn missense_variant 1.0 isoniazid
kasA 2518334 c.220_222delCGAinsAG frameshift_variant&synonymous_variant 1.0 isoniazid
kasA 2518343 p.Met77Leu missense_variant 1.0 isoniazid
kasA 2518348 c.234A>C synonymous_variant 1.0 isoniazid
kasA 2518357 c.243G>C synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518513 c.399C>T synonymous_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518531 c.417G>A synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518564 c.450C>G synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518570 c.456G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518594 c.480C>G synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>C synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>A synonymous_variant 1.0 isoniazid
kasA 2518651 c.537C>G synonymous_variant 1.0 isoniazid
kasA 2518666 c.552G>A synonymous_variant 1.0 isoniazid
kasA 2518669 c.555C>T synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518696 c.582C>G synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518759 c.645C>G synonymous_variant 1.0 isoniazid
kasA 2518780 c.666G>A synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>T synonymous_variant 0.99 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>T synonymous_variant 1.0 isoniazid
kasA 2518822 c.708C>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518879 c.765A>G synonymous_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518898 c.784T>C synonymous_variant 1.0 isoniazid
kasA 2518906 c.792A>C synonymous_variant 1.0 isoniazid
kasA 2518907 c.793T>C synonymous_variant 1.0 isoniazid
kasA 2518915 c.801T>C synonymous_variant 1.0 isoniazid
kasA 2518921 c.807T>C synonymous_variant 1.0 isoniazid
folC 2746300 c.1299C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746307 p.Arg431Thr missense_variant 1.0 para-aminosalicylic_acid
folC 2746309 c.1290G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746312 c.1287G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746321 c.1278A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746331 p.Glu423Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746336 c.1263C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746339 c.1260G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746351 c.1248C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746360 c.1239T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746378 c.1221G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746408 p.Val397Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746420 c.1179A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746455 p.Leu382Met missense_variant 1.0 para-aminosalicylic_acid
folC 2746459 c.1140C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746464 p.Leu379Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2746480 c.1119A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746494 c.1103_1104delAT frameshift_variant 1.0 para-aminosalicylic_acid
folC 2746498 c.1100_1101insCG frameshift_variant 1.0 para-aminosalicylic_acid
folC 2746507 p.Gln364Arg missense_variant 1.0 para-aminosalicylic_acid
folC 2746516 c.1083T>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746519 p.Ser360Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746525 c.1074G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746531 c.1068G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746558 c.1041G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746564 c.1035A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746584 c.1015T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746588 c.1011C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746591 c.1008C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746594 c.1005T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746613 p.Gly329Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746621 c.978C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746631 p.Gly323Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2746642 c.957T>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746669 c.930G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746987 c.612T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747007 p.Ser198Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747020 c.579C>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747040 p.Ile187Val missense_variant 0.95 para-aminosalicylic_acid
folC 2747053 c.546C>T synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.95 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 0.95 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.95 para-aminosalicylic_acid
folC 2747104 p.Asp165Glu missense_variant 0.87 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 0.86 para-aminosalicylic_acid
folC 2747131 c.468C>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747239 c.360T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747245 c.354G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747248 c.351G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747261 p.Lys113Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747274 p.Ser109Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2747290 c.307_309delTCAinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747330 p.His90Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747341 c.258C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747365 c.234G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747398 c.201C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747412 p.Ser63Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747413 p.Arg62Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747425 c.174C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747443 c.156G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2747473 p.Arg42Lys missense_variant 1.0 para-aminosalicylic_acid
folC 2747479 c.120G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747482 c.117G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747500 c.99A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747503 c.96T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747509 c.90T>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782420 c.1623T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782441 c.1602G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782450 c.1593C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 p.Asp516Glu missense_variant 1.0 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782504 c.1539G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782570 c.1473C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782573 c.1470C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782579 c.1464C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782582 p.Asn487Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782586 p.Leu486Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782600 c.1443G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782606 c.1435_1437delGGTinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782612 c.1431T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782651 c.1392T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782654 c.1389G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782900 c.1143C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782960 c.1083C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782987 c.1056C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 c.973_975delGACinsCA frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783071 c.972C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783080 c.963G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783083 c.960G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783119 c.924G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783218 c.825C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783286 p.Ala253Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783287 c.756C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783407 c.636C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783432 p.Ser204Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783596 c.447C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783791 c.252C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783950 c.93C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784324 c.-282G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784327 c.-285G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784333 c.-291G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784354 c.-312T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784357 c.-316_-315delTTinsAC upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784390 c.-348G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784396 c.-354A>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784414 c.-372A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784417 c.-375C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859669 c.750T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859678 c.741A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859687 c.732C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859704 c.715T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859723 c.696T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline
pepQ 2859735 c.684G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859765 c.654G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859771 c.648T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859778 p.Val214Asp missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859780 p.Gln213Ala missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859787 p.Val211Ala missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859801 c.618G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859813 c.606C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859816 c.603G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859834 c.585T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859843 c.576G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859852 c.567A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859864 c.555T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859870 c.549T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859873 c.546T>C synonymous_variant 1.0 clofazimine
bedaquiline
Rv2681 2996587 c.-152G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996593 c.-146T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996602 c.-137G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996608 c.-131A>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996617 c.-122A>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996638 p.Asp178Glu missense_variant 1.0 capreomycin
Rv2680 2996639 c.535_537delCTGinsGC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2996647 c.-92C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996650 c.-89T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996654 p.Gln184Glu missense_variant 1.0 capreomycin Uncertain significance
Rv2680 2996668 p.Asp188Glu missense_variant 1.0 capreomycin
Rv2681 2996671 c.-68C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996683 c.-56G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996686 c.-53C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996692 c.-47G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996698 c.-41A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996699 p.Ala199Thr missense_variant 1.0 capreomycin
Rv2680 2996717 p.Gly205Ser missense_variant 1.0 capreomycin
Rv2681 2996722 c.-17G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996906 c.168A>G synonymous_variant 1.0 capreomycin
Rv2681 2996921 c.183G>A synonymous_variant 1.0 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 1.0 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 1.0 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 1.0 capreomycin
Rv2681 2996972 c.234C>G synonymous_variant 1.0 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 1.0 capreomycin
Rv2681 2996984 c.246C>G synonymous_variant 1.0 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 1.0 capreomycin
Rv2681 2996990 c.252G>C synonymous_variant 1.0 capreomycin
Rv2681 2997013 p.Gly92Ala missense_variant 1.0 capreomycin
Rv2681 2997021 c.283T>C synonymous_variant 1.0 capreomycin
Rv2681 2997028 p.Val97Ala missense_variant 1.0 capreomycin
Rv2681 2997033 p.Ala99Arg missense_variant 1.0 capreomycin
Rv2681 2997053 c.315C>G synonymous_variant 1.0 capreomycin
Rv2681 2997054 p.Ser106Gly missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997057 p.Thr107Ser missense_variant 1.0 capreomycin
Rv2681 2997060 p.Asn108Asp missense_variant 1.0 capreomycin
Rv2681 2997077 c.339C>T synonymous_variant 1.0 capreomycin
Rv2681 2997080 c.342C>G synonymous_variant 1.0 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 1.0 capreomycin
Rv2681 2997098 c.360C>G synonymous_variant 1.0 capreomycin
Rv2681 2997729 c.991_993delGCAinsCC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997751 p.Gly338Ala missense_variant 1.0 capreomycin
Rv2681 2997759 p.Val341Ser missense_variant 1.0 capreomycin
Rv2681 2997764 c.1026A>G synonymous_variant 1.0 capreomycin
Rv2681 2997767 c.1029G>C synonymous_variant 1.0 capreomycin
Rv2681 2997770 c.1032A>G synonymous_variant 1.0 capreomycin
Rv2681 2997775 p.Ala346Glu missense_variant 1.0 capreomycin
Rv2681 2997782 c.1044C>G synonymous_variant 1.0 capreomycin
Rv2681 2997785 c.1047A>G synonymous_variant 1.0 capreomycin
Rv2681 2997794 p.Asp352Glu missense_variant 1.0 capreomycin
Rv2681 2997800 c.1062G>C synonymous_variant 0.92 capreomycin
Rv2681 2997813 p.Thr359Gly missense_variant 1.0 capreomycin
Rv2681 2997825 c.1087_1089delCAAinsGG frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997834 p.Arg366Gly missense_variant 1.0 capreomycin
Rv2681 2997839 c.1101A>C synonymous_variant 1.0 capreomycin
Rv2681 2997845 c.1107C>G synonymous_variant 1.0 capreomycin
Rv2681 2997848 c.1110G>A synonymous_variant 1.0 capreomycin
Rv2752c 3065031 c.1161G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1107delGinsTGCGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065092 c.1096_1100delGCCCAinsC frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065115 c.1077C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065126 p.Ser356Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1060_1062delGCAinsTG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065133 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065146 p.Phe349Tyr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065148 c.1044C>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065288 c.904T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065292 c.900T>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065295 p.Gln299Arg missense_variant 0.9 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065298 p.Asp298Glu missense_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065311 p.Thr294Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065313 c.879A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065324 p.Ala290Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065337 c.855T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065346 p.Ala282Asp missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065352 c.840A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065355 c.837A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065358 c.834C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065361 c.831C>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065369 p.Gln275Glu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065372 c.820A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065373 c.819A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065378 p.Val272Ile missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065381 p.Arg271Gly missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065397 c.795G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065403 c.789C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065418 c.774A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065481 c.711T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065496 c.696G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065517 c.675C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065528 c.664C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065532 c.660A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065541 c.651A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065553 c.639A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065562 c.630T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065576 p.Ala206Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065577 c.615C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065610 c.580_582delACCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065619 c.573C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065625 c.567G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.543T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065666 c.526T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065667 c.525A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065697 c.493_495delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065700 c.492C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065706 c.486G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065715 c.475_477delTATinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065718 c.474G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065721 c.471G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065732 c.460T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065768 p.Glu142Gln missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065862 c.330T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065867 c.325T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065901 c.291A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065908 p.Lys95Arg missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065915 c.277C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065922 c.270T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065928 c.264G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065947 p.Gly82Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065952 c.240C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065976 p.Asp72Glu missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065988 c.204A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066027 c.165C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066071 c.121T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066141 c.51G>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066147 c.45G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066153 c.39C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066158 p.Thr12Pro missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066162 c.30C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066168 c.24A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066171 c.21G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066176 p.Pro6Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066177 c.15T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066192 c.-1A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066195 c.-4A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066196 c.-5C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066204 c.-13G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066210 c.-30_-20delTCTAAAGGTGA upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066228 c.-37T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066260 c.-69T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066264 c.-73C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066268 c.-77T>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066279 c.-88A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066285 c.-96_-94delGCCinsCG upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066290 c.-99G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066291 c.-100G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066294 c.-103C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066306 c.-115T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066309 c.-118T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066312 c.-122_-121delTCinsCG upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066315 c.-124C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066320 c.-129A>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066330 c.-139G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066335 c.-144T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066336 c.-145C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066345 c.-154C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066350 c.-159T>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066360 c.-169T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066371 c.-180A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066402 c.-211C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066452 c.-261T>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066453 c.-262G>A upstream_gene_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066456 c.-265A>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-270_-268delCTTinsTA upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-274G>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066468 c.-277C>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066476 c.-285C>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066483 c.-292T>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066513 c.-322C>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066816 c.-625G>C upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066828 c.-637C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066846 c.-655G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066858 c.-667C>G upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066888 c.-697C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066891 c.-700G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066900 c.-709A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066905 c.-714T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066906 c.-715C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066926 c.-735A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066927 c.-736A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066933 c.-743_-742delGGinsAC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066966 c.-775C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066969 c.-778G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066994 c.-804_-803delCAinsGC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066996 c.-805T>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066999 c.-808C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067006 c.-815A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067011 c.-820C>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067026 c.-837_-835delACCinsGG upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067044 c.-853C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067047 c.-856T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067051 c.-860G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067054 c.-864_-863delAGinsGC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067056 c.-865T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067059 c.-868G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067062 c.-871A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067089 c.-898A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067092 c.-901C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067098 c.-909_-907delGCAinsCC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067102 c.-911T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067232 c.714C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067244 c.702C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067250 c.696G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067271 c.675G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 1.0 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067309 p.Ile213Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067316 c.630A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067706 c.240C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067760 c.186G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067784 c.162C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067839 p.Val36Thr missense_variant 1.0 para-aminosalicylic_acid
thyX 3067841 c.105G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067847 c.99C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067859 c.87C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067901 c.45C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073860 c.612C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.94 para-aminosalicylic_acid
thyA 3073878 c.594G>A synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073893 c.579C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.95 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.92 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.91 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 0.91 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074094 c.378G>C synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074103 c.369C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074121 p.Asp117Glu missense_variant 0.95 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074147 p.Ile109Val missense_variant 0.94 para-aminosalicylic_acid
thyA 3074152 p.Glu107Ala missense_variant 0.94 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAC frameshift_variant&missense_variant 0.93 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074244 c.228A>C synonymous_variant 1.0 para-aminosalicylic_acid
ald 3086858 c.39A>G synonymous_variant 1.0 cycloserine
ald 3086862 c.43C>A synonymous_variant 1.0 cycloserine
ald 3086891 c.72G>C synonymous_variant 1.0 cycloserine
ald 3086897 c.78A>G synonymous_variant 1.0 cycloserine
ald 3086903 c.84T>C synonymous_variant 1.0 cycloserine
ald 3086905 p.Arg29His missense_variant 1.0 cycloserine
ald 3086912 c.93T>C synonymous_variant 1.0 cycloserine
ald 3086922 p.Ile35Val missense_variant 1.0 cycloserine
ald 3086930 c.111A>G synonymous_variant 1.0 cycloserine
ald 3086933 c.114T>C synonymous_variant 1.0 cycloserine
ald 3086936 c.117C>G synonymous_variant 1.0 cycloserine
ald 3086939 c.120A>C synonymous_variant 1.0 cycloserine
ald 3086942 c.123G>A synonymous_variant 1.0 cycloserine
ald 3086951 c.132T>C synonymous_variant 1.0 cycloserine
ald 3086955 p.Thr46Pro missense_variant 1.0 cycloserine
ald 3086966 p.Asp49Glu missense_variant 1.0 cycloserine
ald 3086973 p.Ala52Thr missense_variant 1.0 cycloserine
ald 3086978 c.159A>G synonymous_variant 1.0 cycloserine
ald 3087224 c.405A>G synonymous_variant 1.0 cycloserine
ald 3087233 c.414T>C synonymous_variant 1.0 cycloserine
ald 3087236 c.417A>G synonymous_variant 1.0 cycloserine
ald 3087245 c.426C>T synonymous_variant 1.0 cycloserine
ald 3087251 c.432T>G synonymous_variant 1.0 cycloserine
ald 3087254 c.435C>G synonymous_variant 1.0 cycloserine
ald 3087256 p.Ala146Gly missense_variant 1.0 cycloserine
ald 3087260 c.441C>T synonymous_variant 1.0 cycloserine
ald 3087272 c.453A>C synonymous_variant 1.0 cycloserine
ald 3087290 c.471T>C synonymous_variant 1.0 cycloserine
ald 3087294 c.475C>T synonymous_variant 1.0 cycloserine
Rv3236c 3612654 c.463C>T synonymous_variant 1.0 pyrazinamide
Rv3236c 3612667 c.450T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612685 c.432C>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612688 c.429C>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612694 c.421_423delCGTinsGC frameshift_variant&synonymous_variant 1.0 pyrazinamide Uncertain significance
Rv3236c 3612705 p.Glu138Gln missense_variant 1.0 pyrazinamide
Rv3236c 3612708 p.Leu137Val missense_variant 1.0 pyrazinamide
Rv3236c 3612712 c.405G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612721 c.396G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612724 c.393T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612730 c.387C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
Rv3236c 3612736 c.381T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612757 p.Gly120Ala missense_variant 1.0 pyrazinamide
Rv3236c 3612760 c.357C>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612769 c.348T>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612772 c.345T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612777 p.Asp114Asn missense_variant 1.0 pyrazinamide
Rv3236c 3612780 c.337T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612787 c.330T>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612796 c.321G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612805 c.312T>C synonymous_variant 1.0 pyrazinamide
lpqB 3623375 c.1536T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623379 p.Ala511Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623383 p.Ala510Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623417 c.1494A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623423 c.1488C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623428 c.1483T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623432 c.1479G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623442 p.Ser490Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623465 c.1446G>C synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623474 c.1437C>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623480 c.1431C>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623483 p.Phe476Tyr missense_variant 0.93 bedaquiline
rifampicin
lpqB 3623489 c.1422C>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623492 c.1419T>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623507 c.1404C>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623513 c.1398C>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623528 c.1383G>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623531 p.Gly460Asn missense_variant 0.9 bedaquiline
rifampicin
lpqB 3623627 c.1284T>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623639 c.1272A>G synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3623645 c.1266G>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623648 c.1263A>G synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 0.95 bedaquiline
rifampicin
lpqB 3623660 c.1251A>T synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623666 c.1245A>T synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623676 p.Val412Asn missense_variant 0.95 bedaquiline
rifampicin
lpqB 3623682 p.Thr410Asn missense_variant 0.95 bedaquiline
rifampicin
lpqB 3623684 c.1227T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623687 c.1224C>G synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623702 c.1209G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623729 c.1180_1182delTCGinsAC frameshift_variant&missense_variant 0.95 bedaquiline
rifampicin Uncertain significance
lpqB 3623756 c.1155G>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623771 c.1140C>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623782 p.Val377Ile missense_variant 0.96 bedaquiline
rifampicin
lpqB 3623788 c.1123T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623789 c.1122T>G synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3623800 p.Glu371Gln missense_variant 0.94 bedaquiline
rifampicin
lpqB 3623801 c.1110T>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623807 c.1104T>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623810 c.1101G>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3623816 c.1093_1095delGGGinsCC frameshift_variant&missense_variant 0.88 bedaquiline
rifampicin Uncertain significance
lpqB 3623834 c.1077C>G synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624008 c.903T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624014 c.897T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624032 c.879T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624037 c.874A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624041 p.Glu290Asp missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624050 c.861C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624071 c.840C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624077 c.834G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624082 c.829A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624089 c.822C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624094 c.817A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624100 c.811T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624101 c.810C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624133 c.778A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624172 p.Val247Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624173 c.738A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624176 c.735G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624188 c.723G>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624192 p.Arg240Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624194 c.717C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624200 c.711A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624204 p.Ser236Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624209 c.702A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624224 c.687T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624237 p.Arg225His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624241 c.670C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624242 c.669A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624245 c.666A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624254 c.657T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624263 c.648T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624266 c.645T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624276 p.Arg212His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624278 c.633G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624293 c.618A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624296 c.615T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624299 c.612G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624307 p.Leu202Met missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624308 c.603A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624314 c.597C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624317 c.594C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624341 c.570C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624346 p.Ser189Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624362 c.549G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624371 c.540T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624416 c.495G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624425 c.486A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624452 c.459T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624476 c.435C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624482 c.429T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624485 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624488 c.423C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624518 c.393T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624527 p.Gln128Val missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624530 c.381T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624542 c.369G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624545 c.366T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624551 c.360G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624554 c.357G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624560 c.351G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624563 c.348C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624572 c.339C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624575 c.336T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624581 c.330A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624584 c.327G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624593 p.Val106Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624603 p.Lys103Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624605 c.306G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624613 p.Ser100Gly missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624614 c.297A>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624623 c.288C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624650 c.261G>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624656 c.255C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624671 c.240C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624680 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624698 c.213G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624731 c.180C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624760 c.151C>T synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624785 c.126G>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624806 p.Val35Ala missense_variant 0.94 bedaquiline
rifampicin
lpqB 3624812 c.99T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624824 c.87A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624833 c.78A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625090 c.-180C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Gln missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625135 c.-225A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625138 c.-228C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625186 c.-276T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625258 c.-348G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>T upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625273 c.-363C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.96 bedaquiline
rifampicin
mtrB 3625312 p.Arg434Asp missense_variant 0.93 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 0.96 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625327 c.-417A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625357 c.-447T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625369 c.-459G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625372 c.-462A>G upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625386 p.Ala410Pro missense_variant 0.89 bedaquiline
rifampicin
lpqB 3625396 c.-486G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625406 p.Gln403Gly missense_variant 0.88 bedaquiline
rifampicin
mtrB 3625408 c.1206G>A synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625413 p.Ala401Ser missense_variant 0.88 bedaquiline
rifampicin
lpqB 3625414 c.-504C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625419 p.Leu399Met missense_variant 0.89 bedaquiline
rifampicin
lpqB 3625420 c.-510T>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3625427 p.Leu396Arg missense_variant 0.93 bedaquiline
rifampicin Uncertain significance
lpqB 3625431 c.-521T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625438 c.-528T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625465 c.-555T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625478 p.Asn379Ser missense_variant 0.94 bedaquiline
rifampicin
mtrB 3625480 c.1132_1134delAACinsCG frameshift_variant&missense_variant 0.93 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625483 c.-573C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625486 c.-576G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625489 c.-579A>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625497 c.1117T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625501 c.-591C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625510 c.-600T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625513 c.-603G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625518 c.-608T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625528 c.-618G>T upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625579 c.-669A>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 0.97 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625615 p.Arg333Ala missense_variant 0.96 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 0.96 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.96 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625806 c.808A>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625837 c.777C>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625891 c.-981G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625915 c.699G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625942 c.672C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625945 c.669A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625951 c.663A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625955 p.Leu220Ala missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625967 p.Ala216Ile missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625978 c.636T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625988 p.Thr209Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625993 c.621G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625999 c.615A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626006 p.Ser203Asn missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626009 p.Ala202Lys missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626029 c.585A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626035 c.577_579delCTGinsGC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626048 p.Arg189Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626053 p.Leu187Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626062 c.552T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626101 p.Gln171His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626107 c.507G>C synonymous_variant 0.91 bedaquiline
rifampicin
mtrB 3626125 c.489C>G synonymous_variant 0.91 bedaquiline
rifampicin
mtrB 3626230 c.384T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626239 c.375T>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626245 c.369C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626248 c.366C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626251 c.363T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626254 c.360G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626260 c.354T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626265 p.Pro117Thr missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626272 c.342A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626275 c.339G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626278 c.336G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626284 c.330T>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626293 c.321G>C synonymous_variant 0.94 bedaquiline
rifampicin
mtrB 3626296 c.318T>G synonymous_variant 0.94 bedaquiline
rifampicin
mtrB 3626308 c.306T>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626317 c.297A>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626323 c.291G>C synonymous_variant 0.94 bedaquiline
rifampicin
mtrB 3626326 c.288G>A synonymous_variant 0.94 bedaquiline
rifampicin
mtrB 3626332 c.282T>C synonymous_variant 0.95 bedaquiline
rifampicin
mtrB 3626349 p.Ser89Gly missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626362 c.252A>G synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626377 p.Asp79Glu missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626383 c.231G>C synonymous_variant 0.96 bedaquiline
rifampicin
mtrB 3626386 c.228G>C synonymous_variant 0.96 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626404 c.210C>G synonymous_variant 0.96 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 0.96 bedaquiline
rifampicin
mtrB 3626410 c.204T>G synonymous_variant 0.96 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626437 c.177T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626440 c.174C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626443 c.171T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626449 c.165G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626455 c.159C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626458 c.156C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626461 c.153A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626464 c.150G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626469 c.145C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626476 c.138C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626502 c.112C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626750 c.-137T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626882 c.-269G>A upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3626888 c.460_462delTTGinsCC frameshift_variant&missense_variant 0.97 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626999 c.-386G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627143 c.-530G>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627170 c.-557C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627200 c.-587C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627208 c.142C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627227 c.-614T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627233 c.-620T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627254 c.-641C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627917 c.-568G>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3627920 c.-571A>C upstream_gene_variant 0.9 bedaquiline
rifampicin
fbiB 3640719 c.-816C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640726 c.-809C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640743 c.-792T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640752 c.-783C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640755 c.-780C>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640758 c.-777G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640761 c.-774G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640767 c.-768C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640768 p.Gln76Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640776 c.-759C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640782 c.-753C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640785 p.Gln81His missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640788 c.-747T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640797 c.-738T>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640808 p.Met89Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640810 p.Gln90Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640816 c.-719C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640820 p.Val93Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640827 c.-708T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640849 p.Glu103Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640857 c.-678G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640866 c.-669T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640871 p.Ala110Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640878 c.-657T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640899 c.-636G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640914 c.-621C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640931 p.Glu130Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640935 c.-600C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640938 c.-597A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640944 c.-591T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640952 p.Gln137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640962 c.-573C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640965 c.-570C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640966 c.-569T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640974 c.432T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiB 3640989 c.-546T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641170 p.Met210Leu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3641184 c.-351T>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3641187 c.-348T>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiA 3641200 p.Ile220Val missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3641205 c.-330C>G upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3641226 c.-309G>C upstream_gene_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3641229 c.-306T>C upstream_gene_variant 0.91 clofazimine
pretomanid
delamanid
fbiA 3641234 p.Ala231Gly missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3641239 c.-296T>C upstream_gene_variant 0.9 clofazimine
pretomanid
delamanid
fbiB 3641645 c.111A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641654 c.120A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiB 3641661 p.Gly43Ser missense_variant 0.83 clofazimine
pretomanid
delamanid
fbiB 3641678 c.144T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiB 3641699 c.165A>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiB 3641708 c.174C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiB 3641711 c.177G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiB 3641834 c.300G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641840 c.306T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641846 c.312G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641864 c.330A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641879 c.345G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641880 p.Ser116Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641909 c.375T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641918 c.384T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641924 c.390A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3641928 c.394T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641935 p.Ala134Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641938 p.Gly135Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641961 p.Thr143Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641972 c.438G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641987 c.453C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641993 c.459A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642623 c.1089C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642674 c.1140C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642692 c.1158C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642707 c.1173C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642711 p.Leu393Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642731 c.1197C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642752 p.Asp406Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642753 c.1219C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
alr 3840317 c.1104G>C synonymous_variant 1.0 cycloserine
alr 3840328 c.1093T>C synonymous_variant 1.0 cycloserine
alr 3840329 c.1092T>C synonymous_variant 1.0 cycloserine
alr 3840344 c.1077A>G synonymous_variant 1.0 cycloserine
alr 3840356 c.1065T>C synonymous_variant 1.0 cycloserine
alr 3840359 p.Pro354Leu missense_variant 1.0 cycloserine
alr 3840368 c.1053C>T synonymous_variant 1.0 cycloserine
alr 3840398 c.1023C>T synonymous_variant 1.0 cycloserine
alr 3840404 c.1017G>C synonymous_variant 1.0 cycloserine
alr 3840407 p.Val338Ala missense_variant 1.0 cycloserine
alr 3840410 c.1011T>C synonymous_variant 1.0 cycloserine
alr 3840418 p.Cys335Arg missense_variant 1.0 cycloserine
alr 3840419 c.1002A>G synonymous_variant 1.0 cycloserine
alr 3840422 c.997_999delAGAinsCG frameshift_variant&missense_variant 1.0 cycloserine
alr 3840443 c.978G>C synonymous_variant 0.93 cycloserine
alr 3840461 c.960G>C synonymous_variant 0.93 cycloserine
alr 3840476 c.945A>C synonymous_variant 0.92 cycloserine
alr 3840482 c.939T>C synonymous_variant 0.91 cycloserine
alr 3840944 c.477T>C synonymous_variant 0.8 cycloserine
alr 3840956 c.465C>G synonymous_variant 0.88 cycloserine
alr 3840965 c.456G>C synonymous_variant 0.88 cycloserine
alr 3840968 c.453G>C synonymous_variant 0.88 cycloserine
alr 3840971 c.450G>C synonymous_variant 0.88 cycloserine
alr 3840974 c.447C>G synonymous_variant 0.88 cycloserine
alr 3840993 c.427_428insCG frameshift_variant 0.89 cycloserine
alr 3840996 p.Leu142Ser missense_variant 0.89 cycloserine
alr 3840999 c.420_422delACTinsG frameshift_variant&missense_variant 0.89 cycloserine
alr 3841010 c.411A>G synonymous_variant 0.9 cycloserine
alr 3841018 p.Leu135Val missense_variant 0.9 cycloserine
alr 3841033 p.Val130Ile missense_variant 0.88 cycloserine
alr 3841036 p.Gln129Glu missense_variant 0.92 cycloserine
alr 3841041 p.Asp127Gly missense_variant 0.92 cycloserine
alr 3841055 c.366C>G synonymous_variant 0.92 cycloserine
alr 3841079 c.342T>C synonymous_variant 1.0 cycloserine
alr 3841100 c.321A>C synonymous_variant 1.0 cycloserine
alr 3841106 c.315T>C synonymous_variant 1.0 cycloserine
alr 3841112 c.309T>C synonymous_variant 1.0 cycloserine
alr 3841115 c.306T>C synonymous_variant 1.0 cycloserine
alr 3841127 c.294A>G synonymous_variant 1.0 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 1.0 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 1.0 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877567 p.Ser314Thr missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.98 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.98 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 0.98 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 1.0 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877968 c.540C>G synonymous_variant 1.0 rifampicin
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 0.98 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>C synonymous_variant 0.98 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878088 c.420C>G synonymous_variant 0.98 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 1.0 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.98 rifampicin
rpoA 3878262 c.244_246delAGCinsGT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878415 c.93C>T synonymous_variant 1.0 rifampicin
rpoA 3878432 c.76C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878436 c.72A>G synonymous_variant 1.0 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 1.0 rifampicin
rpoA 3878458 p.Asn17Thr missense_variant 1.0 rifampicin
rpoA 3878472 c.36C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878490 c.18C>A synonymous_variant 1.0 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878728 c.-221G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878749 c.-242G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878785 c.-278T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878806 c.-299C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878836 c.-331_-329delAAGinsGGC upstream_gene_variant 1.0 rifampicin
rpoA 3878842 c.-335G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878845 c.-338G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878890 c.-383C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 1.0 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.98 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoA 3878926 c.-419C>G upstream_gene_variant 0.98 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.98 rifampicin
rpoA 3878962 c.-455G>C upstream_gene_variant 0.98 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.98 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 0.98 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.98 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.98 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 0.98 rifampicin
rpoA 3879079 c.-572A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.99 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.99 rifampicin
rpoA 3879130 c.-623A>G upstream_gene_variant 0.99 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.98 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.97 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.98 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.98 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.98 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.97 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.97 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.97 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.97 delamanid
pretomanid
ddn 3986646 c.-198_-196delCTCinsTG upstream_gene_variant 0.96 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.96 delamanid
pretomanid
ddn 3986696 c.-148G>C upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986963 c.120C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3986978 c.135G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987015 p.Gln58Glu missense_variant 1.0 delamanid
pretomanid
ddn 3987020 c.177G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987023 c.180G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987028 p.Asn62Ser missense_variant 1.0 delamanid
pretomanid
ddn 3987035 c.192C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987042 c.199C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987053 c.210T>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987055 p.Gly71Asp missense_variant 1.0 delamanid
pretomanid
ddn 3987062 c.219C>G synonymous_variant 0.98 delamanid
pretomanid
ddn 3987065 c.222T>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987089 c.246G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987091 p.Glu83Ala missense_variant 1.0 delamanid Uncertain significance
pretomanid
ddn 3987113 c.270C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987119 c.276C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987137 c.294T>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987143 c.300A>G synonymous_variant 1.0 delamanid Not assoc w R - Interim
pretomanid
ddn 3987155 c.312G>A synonymous_variant 1.0 delamanid
pretomanid
ddn 3987158 c.315A>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987164 c.321G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987170 c.327T>G synonymous_variant 1.0 delamanid
pretomanid
clpC1 4038271 p.Pro812Ala missense_variant 0.95 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 0.97 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038329 c.2376G>A synonymous_variant 0.97 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 1.0 pyrazinamide
clpC1 4038440 c.2265C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038461 c.2244G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Thr missense_variant 0.98 pyrazinamide
clpC1 4038488 c.2217C>G synonymous_variant 0.98 pyrazinamide
clpC1 4038498 p.Ser736Thr missense_variant 0.98 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.98 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038559 p.Ile716Val missense_variant 0.94 pyrazinamide
clpC1 4038560 p.Asp715Glu missense_variant 0.94 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.98 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.98 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038857 c.1848C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038884 c.1821C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.98 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039031 c.1674T>G synonymous_variant 0.98 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039040 c.1665C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039043 c.1662G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039100 c.1605C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.98 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039259 c.1446G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1417_1419delCTTinsAG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039316 c.1389G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039433 c.1272C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039581 p.Thr375Ser missense_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039805 c.900C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039817 c.888A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039925 c.779_780delGCinsTCGAGG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4039927 c.774_777delTAGC frameshift_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 0.98 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.97 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>A synonymous_variant 0.97 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040189 c.516C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.95 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.94 pyrazinamide
clpC1 4040219 c.486C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040222 c.483G>A synonymous_variant 0.94 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.94 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040243 c.462C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040285 c.420G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040342 c.363C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.94 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040372 c.333C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>G synonymous_variant 0.96 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.96 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.96 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.95 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040495 c.210C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040539 c.166C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040579 c.126A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.9 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.9 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040603 c.100_102delCTTinsTG frameshift_variant&synonymous_variant 0.9 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.85 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.85 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040669 c.36C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.9 pyrazinamide
clpC1 4040708 c.-4A>G upstream_gene_variant 0.88 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.89 pyrazinamide
clpC1 4040734 c.-31delT upstream_gene_variant 0.94 pyrazinamide
clpC1 4040742 c.-41_-38delGACCinsCCA upstream_gene_variant 0.94 pyrazinamide
clpC1 4040747 c.-43T>C upstream_gene_variant 0.94 pyrazinamide
clpC1 4040750 c.-46G>A upstream_gene_variant 0.94 pyrazinamide
clpC1 4040763 c.-59C>T upstream_gene_variant 0.94 pyrazinamide Uncertain significance
panD 4044024 c.258T>C synonymous_variant 1.0 pyrazinamide
panD 4044033 c.249T>C synonymous_variant 1.0 pyrazinamide
panD 4044036 c.246G>C synonymous_variant 1.0 pyrazinamide
panD 4044042 c.240T>C synonymous_variant 1.0 pyrazinamide
panD 4044050 c.232T>C synonymous_variant 1.0 pyrazinamide
panD 4044051 c.231C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044057 c.225C>G synonymous_variant 0.95 pyrazinamide
panD 4044063 c.219T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
panD 4044072 c.210C>T synonymous_variant 0.95 pyrazinamide
panD 4044075 c.207T>C synonymous_variant 0.95 pyrazinamide
panD 4044081 c.201T>G synonymous_variant 0.95 pyrazinamide
panD 4044084 p.Ser66Thr missense_variant 0.95 pyrazinamide
panD 4044120 c.162A>G synonymous_variant 0.93 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.93 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 0.93 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 0.94 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 0.91 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.9 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 0.92 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.9 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 0.84 pyrazinamide
panD 4044240 c.42G>C synonymous_variant 0.89 pyrazinamide
panD 4044249 c.33C>T synonymous_variant 0.89 pyrazinamide
panD 4044284 c.-3C>T upstream_gene_variant 0.82 pyrazinamide
panD 4044692 c.-411G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044704 c.-423G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044713 c.-432G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044744 c.-463T>A upstream_gene_variant 1.0 pyrazinamide
panD 4044746 c.-465G>T upstream_gene_variant 1.0 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044755 c.-474G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044776 c.-495G>A upstream_gene_variant 1.0 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 1.0 pyrazinamide
panD 4044785 c.-504C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.95 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.95 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.94 pyrazinamide
panD 4044848 c.-567T>C upstream_gene_variant 0.94 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.94 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 1.0 pyrazinamide
glpK 4138232 c.1524G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138238 c.1518G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138250 c.1506C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138253 c.1503C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138259 c.1497T>G synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138268 c.1488T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138273 p.Glu495Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138292 c.1464A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138298 c.1458G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138311 p.Arg482Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138337 p.Ala473Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138352 c.1404C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138360 c.1396T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138361 c.1395C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138376 p.Val460Ala missense_variant 1.0 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138382 c.1374A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138385 c.1371A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138424 c.1332T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138429 c.1327T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138433 c.1323C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138451 c.1305T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138466 c.1290C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138490 c.1266G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138495 p.Gln421Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138496 c.1260G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 c.1237_1239delGAAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138523 c.1233C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138562 c.1194G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138586 c.1170C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138628 c.1128T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138640 c.1116C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138649 c.1107C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138654 c.1102C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138655 c.1101G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138658 c.1098C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138664 c.1092G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138685 c.1071C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138706 c.1050C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138714 p.Ala348Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138733 c.1023C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.997_999delCTAinsTG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138781 c.973_975delGTGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138787 c.969C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138822 p.Asn312Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138823 c.933G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138829 c.927A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138841 c.915G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138847 c.909A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138859 c.895_897delAATinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138865 c.891A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138877 c.879A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138880 c.876T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138889 c.867G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139195 c.561G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139228 c.526_528delCCGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139231 c.525A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139240 c.514_516delTTGinsCT frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139243 c.513A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139249 c.507C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139253 p.Asn168Arg missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139255 c.501G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139265 p.Ala164Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139270 c.486C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139273 c.483A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139276 c.480T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139282 c.474T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139312 c.444T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139315 c.441C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139318 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139321 c.435T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139324 c.432A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139339 c.417G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139348 c.408C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139351 c.405C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139356 p.Leu134Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139359 p.Asn133Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139360 c.396A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139363 c.393T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139366 c.390T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139372 c.384A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139375 c.381T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139393 c.363C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139408 c.348T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139554 p.Ala68Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139567 c.189C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139573 c.183C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139576 c.180G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139594 c.162C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139600 c.156G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139630 c.126C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139642 c.114G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139653 p.His35Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139672 c.84C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139681 c.75C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139690 p.Gln22His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139693 c.63C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139705 c.49_51delATAinsGT frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139729 c.-846_26del frameshift_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
embC 4238999 c.-864C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239014 c.-849C>G upstream_gene_variant 1.0 ethambutol
embC 4239023 c.-840C>G upstream_gene_variant 1.0 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239033 c.-830C>A upstream_gene_variant 1.0 ethambutol
embC 4239057 c.-806A>G upstream_gene_variant 0.95 ethambutol
embC 4239062 c.-801C>G upstream_gene_variant 0.95 ethambutol
embC 4239066 c.-797_-795delCGAinsGC upstream_gene_variant 0.95 ethambutol
embC 4239069 c.-794_-792delTCAinsAC upstream_gene_variant 0.95 ethambutol
embC 4239076 c.-787C>T upstream_gene_variant 0.95 ethambutol
embC 4239079 c.-784_-783delCAinsGG upstream_gene_variant 0.95 ethambutol
embC 4239083 c.-780C>G upstream_gene_variant 0.96 ethambutol
embC 4239107 c.-756G>C upstream_gene_variant 0.96 ethambutol
embC 4239113 c.-750C>G upstream_gene_variant 0.95 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 0.94 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 0.9 ethambutol Uncertain significance
embC 4240459 c.597G>C synonymous_variant 0.89 ethambutol
embC 4240462 c.600G>C synonymous_variant 0.9 ethambutol
embC 4240475 p.Ala205Ser missense_variant 0.91 ethambutol Uncertain significance
embC 4240489 c.627A>G synonymous_variant 0.93 ethambutol
embC 4240495 c.633T>C synonymous_variant 0.93 ethambutol
embC 4240504 c.642C>T synonymous_variant 0.93 ethambutol
embC 4240512 p.Ser217Thr missense_variant 0.92 ethambutol
embC 4240516 c.654G>C synonymous_variant 0.93 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.93 ethambutol
embC 4240543 c.681G>C synonymous_variant 0.94 ethambutol
embC 4240544 p.Pro228Thr missense_variant 0.94 ethambutol
embC 4240547 c.685C>T synonymous_variant 0.94 ethambutol
embC 4240558 c.696C>G synonymous_variant 0.94 ethambutol
embC 4240561 c.699C>G synonymous_variant 0.94 ethambutol
embC 4240576 c.714A>G synonymous_variant 0.97 ethambutol
embC 4240578 p.Ala239Val missense_variant 0.97 ethambutol
embC 4240582 c.720C>G synonymous_variant 0.97 ethambutol
embC 4240585 c.723C>G synonymous_variant 0.94 ethambutol
embC 4240587 p.Gly242Ala missense_variant 0.97 ethambutol
embC 4240600 c.738G>C synonymous_variant 1.0 ethambutol
embC 4240603 c.741G>C synonymous_variant 1.0 ethambutol
embC 4240610 p.Ile250Val missense_variant 1.0 ethambutol
embC 4240630 c.768C>G synonymous_variant 1.0 ethambutol
embC 4240632 p.Met257Thr missense_variant 1.0 ethambutol
embC 4240642 c.780G>C synonymous_variant 1.0 ethambutol
embC 4240645 c.783G>C synonymous_variant 1.0 ethambutol
embC 4240669 c.807G>C synonymous_variant 1.0 ethambutol
embC 4240670 p.Thr270Val missense_variant 1.0 ethambutol
embC 4240675 c.813C>T synonymous_variant 0.98 ethambutol
embC 4240678 c.816T>C synonymous_variant 1.0 ethambutol
embC 4240685 p.Thr275Ala missense_variant 1.0 ethambutol
embC 4240690 c.828G>C synonymous_variant 1.0 ethambutol
embC 4240693 c.831T>C synonymous_variant 1.0 ethambutol
embC 4240707 p.Val282Ala missense_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240735 c.873C>G synonymous_variant 1.0 ethambutol
embC 4240756 c.894G>C synonymous_variant 1.0 ethambutol
embC 4240771 c.909G>C synonymous_variant 1.0 ethambutol
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 1.0 ethambutol
embC 4240828 c.966G>C synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240859 p.Leu333Val missense_variant 1.0 ethambutol
embC 4240867 c.1005T>C synonymous_variant 1.0 ethambutol
embC 4240870 c.1008T>C synonymous_variant 1.0 ethambutol
embC 4240880 p.Ala340Thr missense_variant 1.0 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 1.0 ethambutol
embC 4240897 c.1035C>G synonymous_variant 1.0 ethambutol Not assoc w R
embC 4240900 c.1038A>G synonymous_variant 1.0 ethambutol
embC 4240921 c.1059C>G synonymous_variant 1.0 ethambutol
embC 4240924 c.1062C>G synonymous_variant 1.0 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.98 ethambutol
embC 4240945 c.1083T>C synonymous_variant 0.97 ethambutol
embC 4240948 c.1086G>A synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embC 4240951 c.1089C>G synonymous_variant 0.97 ethambutol
embC 4240954 p.Ile364Met missense_variant 0.97 ethambutol
embC 4240957 c.1095C>G synonymous_variant 0.97 ethambutol
embC 4240966 c.1104G>C synonymous_variant 0.97 ethambutol
embC 4240967 p.His369Asp missense_variant 0.97 ethambutol
embC 4240972 c.1110C>G synonymous_variant 0.97 ethambutol
embC 4240979 p.Thr373Arg missense_variant 0.97 ethambutol
embC 4240983 p.Ser374Asn missense_variant 0.97 ethambutol
embC 4240990 c.1128A>G synonymous_variant 0.98 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.98 ethambutol
embC 4241023 c.1161T>C synonymous_variant 0.98 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.97 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.98 ethambutol
embC 4241084 c.1222C>T synonymous_variant 1.0 ethambutol
embC 4241101 c.1239G>C synonymous_variant 1.0 ethambutol
embC 4241104 c.1242G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>C synonymous_variant 1.0 ethambutol
embC 4241158 c.1296T>C synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>C synonymous_variant 1.0 ethambutol
embC 4241224 c.1362G>A synonymous_variant 1.0 ethambutol
embC 4241230 c.1368A>G synonymous_variant 1.0 ethambutol
embC 4241233 c.1371G>C synonymous_variant 1.0 ethambutol
embC 4241236 c.1374C>G synonymous_variant 1.0 ethambutol
embC 4241248 c.1386G>C synonymous_variant 1.0 ethambutol
embC 4241249 c.1387_1389delCGTinsAG frameshift_variant&missense_variant 1.0 ethambutol
embC 4241256 p.Arg465Lys missense_variant 1.0 ethambutol
embC 4241259 p.Arg466Leu missense_variant 1.0 ethambutol
embC 4241266 c.1404C>T synonymous_variant 1.0 ethambutol
embC 4241268 p.Val469Ala missense_variant 1.0 ethambutol
embC 4241275 c.1413A>C synonymous_variant 1.0 ethambutol
embC 4241288 c.1426_1428delATCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embC 4241301 p.Ala480Val missense_variant 0.97 ethambutol Uncertain significance
embC 4241313 p.Ala484Gly missense_variant 0.92 ethambutol
embC 4241319 p.Pro486Leu missense_variant 0.95 ethambutol
embC 4241326 c.1464T>C synonymous_variant 0.95 ethambutol
embC 4241329 c.1467T>C synonymous_variant 0.95 ethambutol
embC 4241332 c.1470T>C synonymous_variant 0.95 ethambutol
embC 4241338 c.1476C>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4241339 c.1477_1479delTTCinsCG frameshift_variant&missense_variant 0.95 ethambutol
embC 4241344 c.1482G>C synonymous_variant 0.95 ethambutol
embC 4241361 p.Asn500Thr missense_variant 0.96 ethambutol
embC 4241363 p.Leu501Ala missense_variant 0.96 ethambutol
embC 4241374 c.1512T>C synonymous_variant 0.97 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.97 ethambutol
embC 4241394 p.Lys511Ser missense_variant 0.97 ethambutol
embC 4241411 p.Ile517Leu missense_variant 0.93 ethambutol
embC 4241449 c.1587C>G synonymous_variant 1.0 ethambutol
embC 4241452 c.1590G>C synonymous_variant 1.0 ethambutol
embC 4241453 p.Ile531Val missense_variant 1.0 ethambutol
embC 4241470 c.1608C>G synonymous_variant 0.96 ethambutol
embC 4241479 c.1617C>G synonymous_variant 1.0 ethambutol
embC 4241496 p.Ala545Gly missense_variant 1.0 ethambutol
embC 4241498 c.1636_1638delGTAinsAC frameshift_variant&missense_variant 1.0 ethambutol
embC 4241501 c.1639_1641delTCGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embC 4241518 c.1656A>G synonymous_variant 1.0 ethambutol
embC 4241521 c.1659T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241545 c.1683T>C synonymous_variant 1.0 ethambutol
embC 4241548 c.1686T>C synonymous_variant 1.0 ethambutol
embC 4241551 c.1689A>G synonymous_variant 1.0 ethambutol
embC 4241560 c.1698C>G synonymous_variant 1.0 ethambutol
embC 4241567 p.Ile569Val missense_variant 1.0 ethambutol
embC 4241578 c.1716G>C synonymous_variant 1.0 ethambutol
embC 4241584 c.1722T>C synonymous_variant 1.0 ethambutol
embC 4241587 c.1725C>G synonymous_variant 1.0 ethambutol
embC 4241591 p.Leu577Val missense_variant 1.0 ethambutol
embC 4241608 c.1746C>A synonymous_variant 1.0 ethambutol
embC 4241614 c.1752A>C synonymous_variant 1.0 ethambutol
embC 4241617 c.1755G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241626 c.1764T>C synonymous_variant 1.0 ethambutol
embC 4241644 c.1782G>C synonymous_variant 1.0 ethambutol
embC 4241648 c.1786T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241653 c.1791C>G synonymous_variant 1.0 ethambutol
embC 4241656 c.1794G>A synonymous_variant 1.0 ethambutol
embC 4241657 p.Ser599Pro missense_variant 1.0 ethambutol
embC 4241665 c.1803G>T synonymous_variant 1.0 ethambutol
embC 4241671 c.1809T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embC 4241691 p.Gly610Ala missense_variant 0.97 ethambutol Uncertain significance
embC 4241695 c.1833T>G synonymous_variant 0.97 ethambutol
embC 4241704 c.1842C>G synonymous_variant 0.97 ethambutol
embC 4241713 c.1851G>C synonymous_variant 0.97 ethambutol
embC 4241719 c.1857G>C synonymous_variant 0.97 ethambutol
embC 4241741 c.1879_1881delGTCinsCG frameshift_variant&missense_variant 0.96 ethambutol
embC 4241747 p.Val629Leu missense_variant 0.96 ethambutol
embC 4241750 p.Leu630Val missense_variant 0.96 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.96 ethambutol
embC 4241756 c.1894C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embC 4241770 c.1908T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4241788 c.1926C>T synonymous_variant 0.92 ethambutol
embC 4241791 c.1929G>C synonymous_variant 0.92 ethambutol
embC 4241797 c.1935C>T synonymous_variant 0.92 ethambutol
embC 4241809 c.1947A>C synonymous_variant 0.92 ethambutol
embC 4241995 c.2133C>G synonymous_variant 1.0 ethambutol
embC 4242002 c.2140_2142delTTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embC 4242011 p.Leu717Val missense_variant 1.0 ethambutol
embC 4242104 p.Thr748Ser missense_variant 1.0 ethambutol
embC 4242112 c.2250G>C synonymous_variant 1.0 ethambutol
embC 4242121 c.2259A>G synonymous_variant 1.0 ethambutol
embC 4242138 p.Leu759Gln missense_variant 1.0 ethambutol
embC 4242142 c.2280T>C synonymous_variant 1.0 ethambutol
embC 4242151 c.2289A>C synonymous_variant 1.0 ethambutol
embC 4242166 c.2304G>C synonymous_variant 1.0 ethambutol
embC 4242171 p.Thr770Ser missense_variant 1.0 ethambutol
embC 4242175 c.2313G>C synonymous_variant 1.0 ethambutol
embC 4242176 p.Pro772Thr missense_variant 1.0 ethambutol
embC 4242179 p.Leu773Val missense_variant 1.0 ethambutol
embC 4242196 c.2334A>C synonymous_variant 1.0 ethambutol
embC 4242208 c.2346T>G synonymous_variant 1.0 ethambutol
embC 4242214 c.2352C>G synonymous_variant 1.0 ethambutol
embC 4242220 c.2358A>C synonymous_variant 1.0 ethambutol
embC 4242245 p.Thr795Arg missense_variant 1.0 ethambutol
embC 4242574 p.Glu904Asp missense_variant 1.0 ethambutol
embC 4242585 p.Ala908Gly missense_variant 1.0 ethambutol
embC 4242594 p.His911Pro missense_variant 1.0 ethambutol
embA 4242598 c.-635T>C upstream_gene_variant 1.0 ethambutol
embC 4242605 c.2743_2745delATGinsTC frameshift_variant&missense_variant 1.0 ethambutol
embC 4242608 p.Glu916Gln missense_variant 1.0 ethambutol
embC 4242611 c.2749_2751delTTCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embA 4242625 c.-608T>C upstream_gene_variant 1.0 ethambutol
embA 4242628 c.-605C>G upstream_gene_variant 1.0 ethambutol
embC 4242629 c.2767_2769delGCGinsTC frameshift_variant&missense_variant 1.0 ethambutol
embA 4242634 c.-599G>C upstream_gene_variant 1.0 ethambutol
embC 4242651 c.2790_2792delCGC disruptive_inframe_deletion 1.0 ethambutol
embC 4242657 c.2795_2796delCAinsTGGCG missense_variant&conservative_inframe_insertion 1.0 ethambutol
embA 4242673 c.-560G>C upstream_gene_variant 1.0 ethambutol
embC 4242689 p.Val943Ile missense_variant 1.0 ethambutol Uncertain significance
embA 4242694 c.-539G>C upstream_gene_variant 1.0 ethambutol
embA 4242695 c.-538T>C upstream_gene_variant 0.92 ethambutol
embA 4242739 c.-494C>G upstream_gene_variant 1.0 ethambutol
embA 4242742 c.-491C>G upstream_gene_variant 1.0 ethambutol
embA 4242745 c.-488A>G upstream_gene_variant 1.0 ethambutol
embA 4242748 c.-485A>C upstream_gene_variant 1.0 ethambutol
embC 4242762 p.Arg967Gln missense_variant 1.0 ethambutol
embC 4242764 p.Val968Leu missense_variant 1.0 ethambutol
embC 4242779 p.Asn973Asp missense_variant 1.0 ethambutol
embC 4242790 c.2928_2929delCGinsGTCC frameshift_variant&missense_variant 0.92 ethambutol
embC 4242794 c.2932_2934delGCGinsA frameshift_variant&missense_variant 0.92 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.93 ethambutol
embA 4242820 c.-413G>C upstream_gene_variant 0.89 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.95 ethambutol
embA 4242832 c.-401A>C upstream_gene_variant 0.96 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.95 ethambutol
embC 4242847 c.2985C>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4242863 p.Tyr1001Asn missense_variant 0.95 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embA 4242892 c.-341G>C upstream_gene_variant 0.95 ethambutol
embA 4242907 c.-326G>A upstream_gene_variant 0.94 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 1.0 ethambutol
embA 4242922 c.-311C>A upstream_gene_variant 1.0 ethambutol
embC 4242928 c.3066A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4242940 c.-293T>C upstream_gene_variant 1.0 ethambutol
embC 4242941 p.His1027Asn missense_variant 1.0 ethambutol
embA 4242946 c.-287T>C upstream_gene_variant 1.0 ethambutol
embA 4242949 c.-284C>G upstream_gene_variant 1.0 ethambutol
embA 4242952 c.-281T>C upstream_gene_variant 1.0 ethambutol
embC 4242965 p.Ile1035Val missense_variant 0.9 ethambutol Uncertain significance
embA 4244198 c.966C>G synonymous_variant 1.0 ethambutol
embA 4244207 c.975C>G synonymous_variant 1.0 ethambutol
embA 4244213 c.981C>G synonymous_variant 1.0 ethambutol
embA 4244216 c.984C>G synonymous_variant 1.0 ethambutol
embA 4244219 c.987C>G synonymous_variant 1.0 ethambutol
embA 4244222 c.990G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244247 p.Val339Ile missense_variant 1.0 ethambutol
embA 4244250 p.Ser340Gly missense_variant 1.0 ethambutol
embA 4244254 p.Arg341His missense_variant 1.0 ethambutol
embA 4244257 p.Phe342Trp missense_variant 1.0 ethambutol
embA 4244271 c.1039C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244282 c.1050C>G synonymous_variant 1.0 ethambutol
embA 4244284 p.Pro351Arg missense_variant 1.0 ethambutol
embA 4244291 c.1059G>C synonymous_variant 1.0 ethambutol
embA 4244298 p.Ser356Ala missense_variant 1.0 ethambutol
embA 4244309 c.1077C>G synonymous_variant 1.0 ethambutol
embA 4244312 c.1080T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244324 c.1092T>G synonymous_variant 1.0 ethambutol
embA 4244327 c.1095T>C synonymous_variant 1.0 ethambutol
embA 4244340 p.Ser370Ala missense_variant 1.0 ethambutol
embA 4244345 c.1113C>G synonymous_variant 1.0 ethambutol
embA 4244366 c.1134C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244372 c.1140T>G synonymous_variant 1.0 ethambutol
embA 4244396 c.1164T>C synonymous_variant 1.0 ethambutol
embA 4244400 p.Leu390Met missense_variant 1.0 ethambutol Uncertain significance
embA 4244404 p.Val391Ala missense_variant 1.0 ethambutol
embA 4244408 c.1176G>C synonymous_variant 1.0 ethambutol
embA 4244415 c.1183T>C synonymous_variant 1.0 ethambutol
embA 4244426 c.1194G>C synonymous_variant 1.0 ethambutol
embA 4244427 c.1195_1197delTCGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244438 c.1206C>G synonymous_variant 1.0 ethambutol
embA 4244453 c.1221G>T synonymous_variant 1.0 ethambutol
embA 4244456 c.1224C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244615 c.1383G>C synonymous_variant 1.0 ethambutol
embA 4244618 c.1386G>T synonymous_variant 1.0 ethambutol
embA 4244619 c.1387T>C synonymous_variant 1.0 ethambutol
embA 4244633 c.1401C>G synonymous_variant 1.0 ethambutol
embA 4244645 c.1413T>C synonymous_variant 1.0 ethambutol
embA 4244647 c.1416_1419delGGAC frameshift_variant 1.0 ethambutol Uncertain significance
embA 4244654 c.1422_1423insCGAA frameshift_variant 1.0 ethambutol Uncertain significance
embA 4244666 c.1434G>C synonymous_variant 1.0 ethambutol
embA 4244669 c.1437G>C synonymous_variant 1.0 ethambutol
embA 4244675 c.1443A>G synonymous_variant 1.0 ethambutol
embA 4244681 c.1449A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244708 c.1476C>G synonymous_variant 1.0 ethambutol
embA 4244799 c.1570_1572delTTG conservative_inframe_deletion 1.0 ethambutol
embA 4244810 c.1578_1579insCTG conservative_inframe_insertion 1.0 ethambutol
embA 4244822 c.1590G>C synonymous_variant 1.0 ethambutol
embA 4244823 p.Val531Met missense_variant 1.0 ethambutol
embA 4244829 c.1597_1599delTTCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244850 p.Arg540Gly missense_variant 1.0 ethambutol
embA 4244856 p.Ala542Pro missense_variant 1.0 ethambutol
embA 4244873 c.1641C>G synonymous_variant 1.0 ethambutol
embA 4244876 c.1644G>C synonymous_variant 1.0 ethambutol
embA 4244879 c.1647C>G synonymous_variant 1.0 ethambutol
embA 4244885 c.1653A>G synonymous_variant 1.0 ethambutol
embA 4244886 c.1654C>T synonymous_variant 1.0 ethambutol
embA 4244897 c.1665T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 1.0 ethambutol
embA 4244921 c.1689C>G synonymous_variant 1.0 ethambutol
embA 4244930 c.1698G>C synonymous_variant 1.0 ethambutol
embA 4244933 c.1701A>G synonymous_variant 1.0 ethambutol
embA 4244960 c.1728A>G synonymous_variant 1.0 ethambutol
embA 4244978 c.1746G>C synonymous_variant 1.0 ethambutol
embA 4244980 p.Val583Ala missense_variant 1.0 ethambutol
embA 4244982 c.1750T>C synonymous_variant 1.0 ethambutol
embA 4244987 c.1755T>C synonymous_variant 0.97 ethambutol
embA 4244996 c.1764C>T synonymous_variant 1.0 ethambutol
embA 4245008 c.1776T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245014 c.1782C>G synonymous_variant 1.0 ethambutol
embA 4245020 c.1788T>C synonymous_variant 1.0 ethambutol
embA 4245023 c.1791A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245026 c.1794T>C synonymous_variant 1.0 ethambutol
embA 4245029 c.1797T>C synonymous_variant 1.0 ethambutol
embA 4245032 c.1800A>C synonymous_variant 1.0 ethambutol
embA 4245041 c.1809C>G synonymous_variant 1.0 ethambutol
embA 4245050 c.1818C>T synonymous_variant 1.0 ethambutol
embA 4245060 c.1828T>C synonymous_variant 1.0 ethambutol
embA 4245083 c.1851A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245086 c.1854C>G synonymous_variant 1.0 ethambutol
embA 4245089 c.1857G>C synonymous_variant 1.0 ethambutol
embA 4245092 c.1860C>G synonymous_variant 1.0 ethambutol
embA 4245093 p.Ile621Val missense_variant 1.0 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245128 c.1896G>C synonymous_variant 1.0 ethambutol
embA 4245131 c.1899G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245136 p.Tyr635Trp missense_variant 1.0 ethambutol
embA 4245140 c.1908C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245152 c.1920C>G synonymous_variant 1.0 ethambutol
embA 4245158 c.1926C>G synonymous_variant 1.0 ethambutol
embA 4245164 c.1932C>T synonymous_variant 1.0 ethambutol
embA 4245182 c.1950T>C synonymous_variant 1.0 ethambutol
embA 4245189 c.1957C>T synonymous_variant 1.0 ethambutol
embA 4245200 c.1968C>G synonymous_variant 1.0 ethambutol
embA 4245206 c.1974A>G synonymous_variant 1.0 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245222 c.1990_1992delTATinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245464 c.2232C>T synonymous_variant 1.0 ethambutol
embA 4245470 c.2238T>C synonymous_variant 1.0 ethambutol
embA 4245476 c.2244C>T synonymous_variant 1.0 ethambutol
embA 4245477 p.Met749Leu missense_variant 1.0 ethambutol
embA 4245497 c.2265C>G synonymous_variant 1.0 ethambutol
embA 4245512 c.2280G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245514 p.Asp761Ala missense_variant 1.0 ethambutol
embB 4245518 c.-996A>C upstream_gene_variant 1.0 ethambutol
embA 4245519 p.Pro763Ala missense_variant 1.0 ethambutol
embA 4245524 c.2292G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245527 c.-987C>G upstream_gene_variant 1.0 ethambutol
embB 4245530 c.-984T>A upstream_gene_variant 1.0 ethambutol
embA 4245535 p.Ser768Asn missense_variant 1.0 ethambutol
embA 4245540 p.Val770Ile missense_variant 1.0 ethambutol
embB 4245560 c.-954C>G upstream_gene_variant 1.0 ethambutol
embA 4245569 p.Glu779Asp missense_variant 1.0 ethambutol
embB 4245575 c.-939C>G upstream_gene_variant 1.0 ethambutol
embA 4245577 p.Lys782Arg missense_variant 1.0 ethambutol
embB 4245581 c.-933C>G upstream_gene_variant 1.0 ethambutol
embA 4245582 p.Asp784Asn missense_variant 1.0 ethambutol Uncertain significance
embA 4245594 p.Ser788Thr missense_variant 1.0 ethambutol
embB 4245602 c.-912C>G upstream_gene_variant 1.0 ethambutol
embA 4245606 p.Leu792Val missense_variant 1.0 ethambutol
embB 4245611 c.-903C>G upstream_gene_variant 1.0 ethambutol
embB 4245614 c.-900C>T upstream_gene_variant 1.0 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 1.0 ethambutol
embB 4245629 c.-885C>G upstream_gene_variant 1.0 ethambutol
embB 4245635 c.-879A>G upstream_gene_variant 1.0 ethambutol
embA 4245641 c.2409C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245650 p.Ile806Met missense_variant 1.0 ethambutol
embA 4245652 p.Thr807Ser missense_variant 1.0 ethambutol
embB 4245671 c.-843C>G upstream_gene_variant 1.0 ethambutol
embA 4245674 c.2442A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 1.0 ethambutol
embB 4245686 c.-828G>C upstream_gene_variant 1.0 ethambutol
embB 4245692 c.-822G>C upstream_gene_variant 1.0 ethambutol
embA 4245693 c.2461_2463delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245725 c.-789A>C upstream_gene_variant 1.0 ethambutol
embA 4245726 c.2494_2496delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245734 c.-780G>C upstream_gene_variant 1.0 ethambutol
embB 4245737 c.-777A>G upstream_gene_variant 1.0 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 1.0 ethambutol
embB 4245743 c.-771C>G upstream_gene_variant 1.0 ethambutol
embB 4245746 c.-768G>A upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embA 4245771 p.Asn847Ser missense_variant 1.0 ethambutol Uncertain significance
embA 4245785 c.2553G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247404 c.891G>C synonymous_variant 1.0 ethambutol
embB 4247407 c.894G>C synonymous_variant 1.0 ethambutol
embB 4247425 c.912G>C synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.98 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247550 p.Ala346Gly missense_variant 0.97 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>A synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>C synonymous_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247593 c.1080G>C synonymous_variant 0.96 ethambutol
embB 4247621 c.1108C>T synonymous_variant 0.92 ethambutol
embB 4247626 c.1113C>G synonymous_variant 0.9 ethambutol
embB 4247629 c.1116C>G synonymous_variant 1.0 ethambutol
embB 4247875 c.1362G>C synonymous_variant 1.0 ethambutol
embB 4247881 c.1368G>C synonymous_variant 1.0 ethambutol
embB 4247887 c.1374C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247909 c.1396T>C synonymous_variant 1.0 ethambutol
embB 4247920 c.1407T>G synonymous_variant 0.97 ethambutol
embB 4247938 c.1425G>C synonymous_variant 0.93 ethambutol
embB 4247940 p.Leu476Trp missense_variant 1.0 ethambutol
embB 4247945 c.1432T>C synonymous_variant 1.0 ethambutol
embB 4247950 c.1437G>C synonymous_variant 0.93 ethambutol
embB 4247951 c.1438_1440delTCGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247956 c.1443G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247971 c.1458C>G synonymous_variant 0.92 ethambutol
embB 4247983 c.1470G>C synonymous_variant 0.93 ethambutol
embB 4248025 c.1512A>G synonymous_variant 0.93 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.97 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.97 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.97 ethambutol
embB 4248052 c.1539G>A synonymous_variant 0.94 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.95 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.98 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.98 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 1.0 ethambutol
embB 4248253 c.1740C>G synonymous_variant 0.95 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.95 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.91 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.96 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.91 ethambutol
embB 4248334 c.1821C>G synonymous_variant 0.89 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.93 ethambutol
embB 4248346 c.1833G>C synonymous_variant 0.85 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.92 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.91 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.91 ethambutol
embB 4248360 p.Pro616His missense_variant 0.82 ethambutol
embB 4248362 p.Ser617Glu missense_variant 0.91 ethambutol
embB 4249255 c.2742G>C synonymous_variant 1.0 ethambutol
embB 4249259 p.Met916Leu missense_variant 1.0 ethambutol
embB 4249268 p.Asp919Tyr missense_variant 1.0 ethambutol
embB 4249276 c.2763A>G synonymous_variant 1.0 ethambutol
embB 4249277 p.Tyr922Asn missense_variant 1.0 ethambutol
embB 4249282 c.2769A>G synonymous_variant 1.0 ethambutol
embB 4249314 p.Phe934Tyr missense_variant 1.0 ethambutol
embB 4249321 c.2808A>C synonymous_variant 1.0 ethambutol
embB 4249322 c.2809_2811delGCAinsTG frameshift_variant&stop_gained 1.0 ethambutol
embB 4249325 p.Lys938Gln missense_variant 1.0 ethambutol
embB 4249336 c.2823C>G synonymous_variant 1.0 ethambutol
embB 4249339 c.2826T>C synonymous_variant 1.0 ethambutol
embB 4249369 c.2856T>C synonymous_variant 1.0 ethambutol
embB 4249375 c.2862G>C synonymous_variant 1.0 ethambutol
embB 4249381 c.2868A>G synonymous_variant 1.0 ethambutol
embB 4249387 p.Glu958Asp missense_variant 1.0 ethambutol
embB 4249411 c.2898G>A synonymous_variant 1.0 ethambutol
embB 4249417 c.2904A>G synonymous_variant 1.0 ethambutol
embB 4249423 p.Asp970Glu missense_variant 1.0 ethambutol Uncertain significance
embB 4249432 c.2919A>G synonymous_variant 1.0 ethambutol
embB 4249441 c.2928A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 1.0 ethambutol
embB 4249447 c.2934G>C synonymous_variant 1.0 ethambutol
embB 4249454 p.Thr981Ser missense_variant 1.0 ethambutol
embB 4249457 p.Gln982Ala missense_variant 1.0 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249487 c.2974T>C synonymous_variant 1.0 ethambutol
embB 4249492 c.2979C>G synonymous_variant 1.0 ethambutol
embB 4249505 p.Gln998Lys missense_variant 1.0 ethambutol
embB 4249523 c.3010_3012delAATinsGC frameshift_variant&missense_variant 1.0 ethambutol
embB 4249529 p.Ile1006Val missense_variant 1.0 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 1.0 ethambutol
embB 4249558 c.3045A>G synonymous_variant 1.0 ethambutol
embB 4249568 p.Ser1019Asn missense_variant 1.0 ethambutol
embB 4249573 c.3060T>C synonymous_variant 1.0 ethambutol
embB 4249581 p.Leu1023Gln missense_variant 1.0 ethambutol
embB 4249594 c.3081G>C synonymous_variant 1.0 ethambutol
embB 4249600 c.3087A>G synonymous_variant 1.0 ethambutol
embB 4249607 p.Thr1032Val missense_variant 1.0 ethambutol
embB 4249624 c.3111C>G synonymous_variant 0.97 ethambutol
embB 4249627 c.3114G>C synonymous_variant 1.0 ethambutol
embB 4249640 c.3127T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249648 c.3135G>C synonymous_variant 1.0 ethambutol
embB 4249657 c.3144C>G synonymous_variant 1.0 ethambutol
embB 4249661 p.Ala1050Ser missense_variant 1.0 ethambutol
embB 4249686 p.Ala1058Gly missense_variant 1.0 ethambutol
embB 4249693 c.3180T>C synonymous_variant 1.0 ethambutol
embB 4249699 c.3186T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249702 c.3189C>G synonymous_variant 1.0 ethambutol
embB 4249717 p.Asp1068Glu missense_variant 1.0 ethambutol
embB 4249720 c.3207C>G synonymous_variant 1.0 ethambutol
embB 4249721 c.3208_3210delCTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embB 4249725 p.Val1071Ala missense_variant 1.0 ethambutol
embB 4249734 p.Pro1074Gln missense_variant 1.0 ethambutol
embB 4249741 c.3228C>G synonymous_variant 1.0 ethambutol
embB 4249750 p.Glu1079Asp missense_variant 1.0 ethambutol
embB 4249751 c.3238T>C synonymous_variant 1.0 ethambutol
embB 4249774 c.3261C>G synonymous_variant 1.0 ethambutol
embB 4249775 c.3262C>T synonymous_variant 1.0 ethambutol
aftB 4267238 c.1599C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267244 c.1593T>C synonymous_variant 1.0 ethambutol
aftB 4267253 c.1584T>C synonymous_variant 0.93 ethambutol
aftB 4267256 c.1581C>G synonymous_variant 1.0 ethambutol
aftB 4267262 c.1575T>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4267266 p.Ala524Gly missense_variant 0.93 ethambutol
aftB 4267268 c.1569T>C synonymous_variant 0.93 ethambutol
aftB 4267274 c.1563G>C synonymous_variant 0.93 ethambutol
aftB 4267290 p.Ala516Gln missense_variant 0.93 ethambutol
aftB 4267295 c.1540_1542delTTGinsCC frameshift_variant&missense_variant 0.93 ethambutol Uncertain significance
aftB 4267305 p.Val511Ala missense_variant 0.93 ethambutol
aftB 4267310 c.1527G>T synonymous_variant 0.93 ethambutol
aftB 4267316 c.1521A>G synonymous_variant 0.93 ethambutol
aftB 4267334 c.1503T>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4267355 c.1482A>C synonymous_variant 0.92 ethambutol
aftB 4267366 p.Met491Leu missense_variant 0.9 ethambutol
aftB 4267496 p.Glu447Asp missense_variant 1.0 ethambutol
aftB 4267510 p.Asn443Asp missense_variant 0.93 ethambutol
aftB 4267511 c.1326C>G synonymous_variant 0.93 ethambutol
aftB 4267514 c.1323G>C synonymous_variant 0.93 ethambutol
aftB 4267517 c.1320A>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4267520 c.1317T>G synonymous_variant 0.94 ethambutol
aftB 4267529 c.1308T>C synonymous_variant 0.94 ethambutol
aftB 4267535 c.1300_1302delCGAinsAG frameshift_variant&missense_variant 0.95 ethambutol Uncertain significance
aftB 4267544 c.1293T>C synonymous_variant 0.95 ethambutol
aftB 4267547 c.1290C>G synonymous_variant 0.95 ethambutol
aftB 4267559 c.1278C>G synonymous_variant 0.96 ethambutol
aftB 4267571 c.1266T>C synonymous_variant 0.96 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
aftB 4267619 c.1218C>A synonymous_variant 0.94 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.94 ethambutol
aftB 4267634 p.Arg401His missense_variant 0.93 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4267655 c.1182C>G synonymous_variant 0.91 ethambutol
aftB 4267658 c.1177_1179delCCGinsTC frameshift_variant&missense_variant 0.9 ethambutol Uncertain significance
aftB 4268078 c.759C>A synonymous_variant 0.9 ethambutol
aftB 4268081 c.756A>G synonymous_variant 0.91 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.92 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4268105 c.732T>C synonymous_variant 0.92 ethambutol
aftB 4268116 c.721C>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4268120 c.717C>G synonymous_variant 0.92 ethambutol
aftB 4268123 c.712_714delAGTinsGC frameshift_variant&synonymous_variant 0.92 ethambutol Uncertain significance
aftB 4268126 c.711G>C synonymous_variant 0.92 ethambutol
aftB 4268138 c.699A>G synonymous_variant 0.93 ethambutol
aftB 4268144 c.693T>C synonymous_variant 0.93 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.94 ethambutol
aftB 4268177 c.658_660delTTGinsCC frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
aftB 4268183 c.654A>G synonymous_variant 0.94 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.93 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.92 ethambutol
aftB 4268386 c.451T>C synonymous_variant 1.0 ethambutol
aftB 4268393 c.444G>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4268404 c.433T>C synonymous_variant 0.94 ethambutol
aftB 4268406 p.Val144Thr missense_variant 0.94 ethambutol
aftB 4268411 c.426G>C synonymous_variant 0.94 ethambutol
aftB 4268435 c.402C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4268441 c.396C>T synonymous_variant 0.94 ethambutol
aftB 4268444 c.393C>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4268450 c.387A>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4268455 p.Val128Leu missense_variant 0.88 ethambutol
aftB 4268462 c.375T>C synonymous_variant 0.93 ethambutol
aftB 4268465 c.372A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4268470 c.367C>T synonymous_variant 0.93 ethambutol
aftB 4268471 c.366G>C synonymous_variant 0.93 ethambutol
aftB 4268480 c.357G>C synonymous_variant 0.95 ethambutol
aftB 4268483 c.354T>G synonymous_variant 0.96 ethambutol
aftB 4268498 c.339T>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
aftB 4268513 c.324C>G synonymous_variant 1.0 ethambutol
aftB 4268516 c.321A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268524 c.313T>C synonymous_variant 1.0 ethambutol
aftB 4268525 c.312G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268533 p.Thr102Ala missense_variant 1.0 ethambutol Uncertain significance
aftB 4268534 c.303G>C synonymous_variant 1.0 ethambutol
aftB 4268543 c.294C>G synonymous_variant 1.0 ethambutol
aftB 4268548 c.289C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268550 p.Val96Ala missense_variant 1.0 ethambutol
aftB 4268554 p.Met95Val missense_variant 1.0 ethambutol
aftB 4268555 c.282A>T synonymous_variant 1.0 ethambutol
aftB 4268563 p.Leu92Val missense_variant 1.0 ethambutol
aftB 4268570 p.Val89Thr missense_variant 1.0 ethambutol
aftB 4268575 p.Met88Leu missense_variant 1.0 ethambutol
aftB 4268582 c.255C>G synonymous_variant 1.0 ethambutol
aftB 4268587 c.250T>C synonymous_variant 1.0 ethambutol
aftB 4268602 p.Leu79Met missense_variant 1.0 ethambutol
aftB 4268626 p.Gly71Ser missense_variant 1.0 ethambutol
aftB 4268630 c.207G>C synonymous_variant 1.0 ethambutol
aftB 4268955 c.-119A>G upstream_gene_variant 1.0 ethambutol
aftB 4268958 c.-122A>C upstream_gene_variant 1.0 ethambutol
aftB 4268964 c.-128G>C upstream_gene_variant 1.0 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 1.0 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
ubiA 4269003 c.831C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 1.0 ethambutol
aftB 4269009 c.-173A>G upstream_gene_variant 1.0 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 1.0 ethambutol
aftB 4269018 c.-182G>C upstream_gene_variant 1.0 ethambutol
aftB 4269027 c.-191C>G upstream_gene_variant 1.0 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 1.0 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269059 p.Ile259Val missense_variant 1.0 ethambutol Uncertain significance
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 1.0 ethambutol
ubiA 4269088 p.Ala249Val missense_variant 1.0 ethambutol Uncertain significance
ubiA 4269096 c.736_737delTC frameshift_variant 1.0 ethambutol
ubiA 4269104 c.729_730delCAinsG frameshift_variant&stop_gained&missense_variant 1.0 ethambutol
ubiA 4269107 p.Tyr243Asp missense_variant 1.0 ethambutol
ubiA 4269111 c.722_723insACA disruptive_inframe_insertion 1.0 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 1.0 ethambutol
aftB 4269143 c.-307T>C upstream_gene_variant 1.0 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
ubiA 4269164 p.Leu224Met missense_variant 1.0 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 1.0 ethambutol
aftB 4269192 c.-356C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 1.0 ethambutol
ubiA 4269243 p.His197Gln missense_variant 1.0 ethambutol
aftB 4269516 c.-680G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269521 p.Val105Leu missense_variant 1.0 ethambutol
ubiA 4269523 p.Thr104Ser missense_variant 1.0 ethambutol
aftB 4269528 c.-692G>C upstream_gene_variant 1.0 ethambutol
aftB 4269564 c.-728G>C upstream_gene_variant 1.0 ethambutol
ethA 4326073 c.1401C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
ethA 4326085 c.1389T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
ethA 4326100 c.1374T>C synonymous_variant 1.0 ethionamide
ethA 4326115 c.1359A>G synonymous_variant 1.0 ethionamide
ethA 4326118 c.1356T>C synonymous_variant 1.0 ethionamide
ethA 4326138 c.1336C>T synonymous_variant 1.0 ethionamide
ethA 4326145 c.1329G>C synonymous_variant 1.0 ethionamide
ethA 4326163 c.1311T>C synonymous_variant 1.0 ethionamide
ethA 4326166 c.1308A>C synonymous_variant 1.0 ethionamide
ethA 4326184 c.1290C>G synonymous_variant 1.0 ethionamide
ethA 4326187 c.1287G>T synonymous_variant 1.0 ethionamide
ethA 4326193 c.1281A>G synonymous_variant 1.0 ethionamide
ethA 4326199 c.1275T>C synonymous_variant 1.0 ethionamide
ethA 4326211 p.Arg421His missense_variant 1.0 ethionamide
ethA 4326217 c.1257C>G synonymous_variant 1.0 ethionamide
ethA 4326258 c.1216T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
ethA 4326261 c.1213T>C synonymous_variant 1.0 ethionamide
ethA 4326262 c.1212C>G synonymous_variant 1.0 ethionamide
ethA 4326265 c.1209T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
ethA 4326269 p.Val402Ala missense_variant 1.0 ethionamide
ethA 4326271 c.1203T>C synonymous_variant 1.0 ethionamide
ethA 4326285 c.1189C>T synonymous_variant 1.0 ethionamide
ethA 4326286 c.1188C>T synonymous_variant 1.0 ethionamide
ethA 4326304 c.1170C>G synonymous_variant 1.0 ethionamide
ethA 4326307 c.1167C>G synonymous_variant 1.0 ethionamide
ethA 4326310 c.1164T>C synonymous_variant 1.0 ethionamide
ethR 4326847 c.-702G>C upstream_gene_variant 0.85 ethionamide
ethR 4326853 c.-696G>A upstream_gene_variant 0.88 ethionamide
ethR 4326880 c.-669G>A upstream_gene_variant 0.88 ethionamide
ethR 4326883 c.-666C>G upstream_gene_variant 0.88 ethionamide
ethA 4326886 p.Asp196Glu missense_variant 0.88 ethionamide Uncertain significance
ethA 4326894 p.Leu194Met missense_variant 0.88 ethionamide
ethR 4326904 c.-645G>C upstream_gene_variant 0.87 ethionamide
ethR 4326916 c.-633C>G upstream_gene_variant 0.94 ethionamide
ethR 4326919 c.-630T>G upstream_gene_variant 0.95 ethionamide
ethR 4326925 c.-624A>G upstream_gene_variant 0.95 ethionamide
ethA 4326942 p.Ile178Val missense_variant 1.0 ethionamide Uncertain significance
ethA 4326949 p.Ala175Gly missense_variant 1.0 ethionamide
ethA 4326953 p.Asp174Ala missense_variant 1.0 ethionamide
ethR 4326985 c.-564A>G upstream_gene_variant 1.0 ethionamide
ethR 4326997 c.-552C>G upstream_gene_variant 1.0 ethionamide
ethA 4327225 c.249G>A synonymous_variant 0.93 ethionamide Not assoc w R - Interim
ethR 4327234 c.-315G>C upstream_gene_variant 0.93 ethionamide
ethA 4327237 p.Lys79Gly missense_variant 0.93 ethionamide
ethR 4327252 c.-297C>G upstream_gene_variant 0.96 ethionamide
ethR 4327258 c.-291C>G upstream_gene_variant 0.96 ethionamide
ethA 4327261 p.Gly71Glu missense_variant 0.96 ethionamide
ethR 4327270 c.-279G>C upstream_gene_variant 0.96 ethionamide
ethR 4327273 c.-276A>G upstream_gene_variant 0.96 ethionamide
ethR 4327279 c.-270T>C upstream_gene_variant 0.96 ethionamide
ethR 4327285 c.-264A>C upstream_gene_variant 0.96 ethionamide
ethR 4327288 c.-261T>C upstream_gene_variant 0.96 ethionamide
ethR 4327291 c.-258C>T upstream_gene_variant 0.96 ethionamide
ethR 4327303 c.-246G>C upstream_gene_variant 0.97 ethionamide
ethR 4327312 c.-237G>A upstream_gene_variant 0.97 ethionamide
ethR 4327315 c.-234A>G upstream_gene_variant 0.97 ethionamide
ethR 4327318 c.-231T>G upstream_gene_variant 0.97 ethionamide
ethR 4327324 c.-225A>G upstream_gene_variant 0.97 ethionamide
ethR 4327327 c.-222A>G upstream_gene_variant 0.97 ethionamide
ethR 4327336 c.-213A>G upstream_gene_variant 0.97 ethionamide
ethR 4327348 c.-201G>C upstream_gene_variant 0.97 ethionamide
ethA 4327356 p.Ser40Ala missense_variant 0.96 ethionamide
ethA 4327357 p.Glu39Ala missense_variant 0.96 ethionamide
ethR 4327360 c.-189C>T upstream_gene_variant 0.96 ethionamide
ethR 4327366 c.-183T>C upstream_gene_variant 0.96 ethionamide
ethR 4327396 c.-153A>G upstream_gene_variant 1.0 ethionamide
ethR 4327423 c.-126G>C upstream_gene_variant 1.0 ethionamide
ethR 4327426 c.-123A>G upstream_gene_variant 1.0 ethionamide
ethR 4327435 c.-114T>G upstream_gene_variant 1.0 ethionamide
ethR 4327438 c.-111A>G upstream_gene_variant 1.0 ethionamide