TB-Profiler

TB-Profiler result

Run: ERR4811493

This average coverage of the target regions is below the recommended 30x. Some mutations may not be detected due to low coverage.

Summary

Run ID: ERR4811493

Sample name:

Date: 2024-04-15T13:59:32.143810

Number of reads: 1891505

Percentage reads mapped: 20.06

Median coverage: 4.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs

Lineage	Family	RDs	Frequency
lineage6.1.3	West-Africa 2	RD702	0.08
lineage4.9	Euro-American (H37Rv-like)	None	0.74

Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin
isoniazid	kasA	p.Arg121Lys		Mutation from literature
ethambutol	embB	p.Ala356Val	Uncertain significance	Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin	gyrB	p.Thr500Asn	Uncertain significance	Mutation from literature
ofloxacin
levofloxacin	gyrB	p.Thr500Asn	Uncertain significance	Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid	fgd1	c.895_897delCAAinsGG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
delamanid	fbiC	c.550_552delCAAinsGG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC	fbiC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.1549_1551delCTTinsTG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.2344_2346delTCGinsCC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.2371_2373delCTTinsTG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiA	c.166_168delCTGinsGA	Assoc w R - Interim	Confers DLM-PMD cross-resistance
bedaquiline
linezolid

Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
gyrB	6738	p.Thr500Asn	missense_variant	1.0	levofloxacin	Uncertain significance	Mutation from literature
gyrB	6738	p.Thr500Asn	missense_variant	1.0	moxifloxacin	Uncertain significance	Mutation from literature
fgd1	491677	c.895_897delCAAinsGG	frameshift_variant&missense_variant	0.95	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491677	c.895_897delCAAinsGG	frameshift_variant&missense_variant	0.95	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1303480	c.550_552delCAAinsGG	frameshift_variant&missense_variant	1.0	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1303480	c.550_552delCAAinsGG	frameshift_variant&missense_variant	1.0	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1303969	c.1039_1041delGTTinsAC	frameshift_variant&missense_variant	0.95	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1303969	c.1039_1041delGTTinsAC	frameshift_variant&missense_variant	0.95	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304479	c.1549_1551delCTTinsTG	frameshift_variant&missense_variant	0.93	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304479	c.1549_1551delCTTinsTG	frameshift_variant&missense_variant	0.93	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1305274	c.2344_2346delTCGinsCC	frameshift_variant&missense_variant	0.96	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1305274	c.2344_2346delTCGinsCC	frameshift_variant&missense_variant	0.96	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1305301	c.2371_2373delCTTinsTG	frameshift_variant&missense_variant	0.97	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1305301	c.2371_2373delCTTinsTG	frameshift_variant&missense_variant	0.97	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1305331	c.2401_2403delGAAinsAC	frameshift_variant&missense_variant	0.99	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1305331	c.2401_2403delGAAinsAC	frameshift_variant&missense_variant	0.99	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
kasA	2518476	p.Arg121Lys	missense_variant	1.0	isoniazid		Mutation from literature
fbiA	3640708	c.166_168delCTGinsGA	frameshift_variant&missense_variant	0.7	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiA	3640708	c.166_168delCTGinsGA	frameshift_variant&missense_variant	0.7	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
embB	4247580	p.Ala356Val	missense_variant	0.99	ethambutol	Uncertain significance	Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
dnaA	504	c.504T>C	synonymous_variant	1.0	isoniazid
dnaA	510	c.510T>G	synonymous_variant	1.0	isoniazid
dnaA	516	c.516C>T	synonymous_variant	1.0	isoniazid
dnaA	522	c.522T>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	525	c.525T>C	synonymous_variant	1.0	isoniazid
dnaA	528	c.528G>C	synonymous_variant	1.0	isoniazid
dnaA	534	c.534T>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	541	c.541_543delGCCinsAG	frameshift_variant&missense_variant	1.0	isoniazid	Uncertain significance
dnaA	558	c.558G>C	synonymous_variant	1.0	isoniazid
dnaA	570	c.570C>G	synonymous_variant	1.0	isoniazid
dnaA	571	c.571T>C	synonymous_variant	1.0	isoniazid
dnaA	576	c.576G>C	synonymous_variant	1.0	isoniazid
dnaA	582	c.582A>C	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
dnaA	591	c.591C>G	synonymous_variant	0.97	isoniazid
dnaA	594	c.594C>A	synonymous_variant	0.98	isoniazid	Not assoc w R - Interim
dnaA	600	c.600T>C	synonymous_variant	0.98	isoniazid
dnaA	624	c.624C>T	synonymous_variant	0.98	isoniazid	Not assoc w R - Interim
dnaA	627	c.627G>A	synonymous_variant	0.98	isoniazid
dnaA	636	c.636C>G	synonymous_variant	0.98	isoniazid
dnaA	639	c.639C>T	synonymous_variant	0.98	isoniazid
dnaA	645	c.645A>T	synonymous_variant	0.98	isoniazid
dnaA	654	c.654A>G	synonymous_variant	0.98	isoniazid
dnaA	663	c.663A>C	synonymous_variant	0.96	isoniazid
dnaA	672	c.672T>C	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
dnaA	673	p.Ala225Thr	missense_variant	0.95	isoniazid	Uncertain significance
dnaA	678	c.678A>G	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
dnaA	682	c.682T>C	synonymous_variant	0.95	isoniazid
dnaA	687	c.687C>T	synonymous_variant	0.95	isoniazid
dnaA	690	c.690G>C	synonymous_variant	0.95	isoniazid
dnaA	693	c.693A>G	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
dnaA	699	c.699G>C	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
dnaA	705	c.705A>G	synonymous_variant	0.95	isoniazid
dnaA	708	c.708T>C	synonymous_variant	0.95	isoniazid
dnaA	720	c.720G>A	synonymous_variant	0.95	isoniazid
dnaA	723	c.723A>G	synonymous_variant	0.95	isoniazid
dnaA	741	c.741T>C	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.85	levofloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.85	moxifloxacin	Not assoc w R - Interim
gyrB	6242	p.Arg335Lys	missense_variant	0.85	levofloxacin
gyrB	6242	p.Arg335Lys	missense_variant	0.85	moxifloxacin
gyrB	6250	c.1011A>G	synonymous_variant	0.87	levofloxacin	Not assoc w R - Interim
gyrB	6250	c.1011A>G	synonymous_variant	0.87	moxifloxacin	Not assoc w R - Interim
gyrB	6253	c.1014G>C	synonymous_variant	0.93	levofloxacin
gyrB	6253	c.1014G>C	synonymous_variant	0.93	moxifloxacin
gyrB	6256	c.1017G>A	synonymous_variant	0.9	levofloxacin
gyrB	6256	c.1017G>A	synonymous_variant	0.9	moxifloxacin
gyrB	6265	c.1026C>T	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6265	c.1026C>T	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6286	c.1047T>C	synonymous_variant	0.94	levofloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.94	moxifloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.94	levofloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.94	moxifloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.94	levofloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.94	moxifloxacin
gyrB	6299	c.1060C>T	synonymous_variant	0.94	levofloxacin
gyrB	6299	c.1060C>T	synonymous_variant	0.94	moxifloxacin
gyrB	6307	c.1068T>G	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrB	6307	c.1068T>G	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	6310	c.-992G>C	upstream_gene_variant	0.94	levofloxacin
gyrA	6310	c.-992G>C	upstream_gene_variant	0.94	moxifloxacin
gyrB	6324	c.1085_1086insGTCC	frameshift_variant	0.97	levofloxacin	Uncertain significance
gyrB	6324	c.1085_1086insGTCC	frameshift_variant	0.97	moxifloxacin
gyrB	6327	c.1090_1093delGAAC	frameshift_variant	0.94	levofloxacin	Uncertain significance
gyrB	6327	c.1090_1093delGAAC	frameshift_variant	0.94	moxifloxacin
gyrA	6346	c.-956C>G	upstream_gene_variant	0.94	levofloxacin
gyrA	6346	c.-956C>G	upstream_gene_variant	0.94	moxifloxacin
gyrA	6361	c.-941G>A	upstream_gene_variant	0.94	levofloxacin
gyrA	6361	c.-941G>A	upstream_gene_variant	0.94	moxifloxacin
gyrA	6362	c.-940T>C	upstream_gene_variant	0.94	levofloxacin
gyrA	6362	c.-940T>C	upstream_gene_variant	0.94	moxifloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	0.92	levofloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	0.92	moxifloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	0.96	levofloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	0.96	moxifloxacin
gyrA	6610	c.-692C>G	upstream_gene_variant	0.88	levofloxacin
gyrA	6610	c.-692C>G	upstream_gene_variant	0.88	moxifloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	0.88	levofloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	0.88	moxifloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.92	levofloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.92	moxifloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	0.92	levofloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	0.92	moxifloxacin
gyrA	6625	c.-677G>A	upstream_gene_variant	0.92	levofloxacin
gyrA	6625	c.-677G>A	upstream_gene_variant	0.92	moxifloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	0.92	levofloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	0.92	moxifloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	0.92	levofloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	0.92	moxifloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	0.92	levofloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	0.92	moxifloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.92	levofloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.92	moxifloxacin
gyrA	6646	c.-656C>T	upstream_gene_variant	0.93	levofloxacin
gyrA	6646	c.-656C>T	upstream_gene_variant	0.93	moxifloxacin
gyrA	6649	c.-653T>C	upstream_gene_variant	0.96	levofloxacin
gyrA	6649	c.-653T>C	upstream_gene_variant	0.96	moxifloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	0.98	moxifloxacin
gyrA	6700	c.-602T>C	upstream_gene_variant	0.99	levofloxacin
gyrA	6700	c.-602T>C	upstream_gene_variant	0.99	moxifloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6724	c.1485G>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6724	c.1485G>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6730	c.-572A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6730	c.-572A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6763	c.-539G>T	upstream_gene_variant	1.0	levofloxacin
gyrA	6763	c.-539G>T	upstream_gene_variant	1.0	moxifloxacin
gyrA	6775	c.-527G>T	upstream_gene_variant	1.0	levofloxacin
gyrA	6775	c.-527G>T	upstream_gene_variant	1.0	moxifloxacin
gyrA	6778	c.-524C>T	upstream_gene_variant	1.0	levofloxacin
gyrA	6778	c.-524C>T	upstream_gene_variant	1.0	moxifloxacin
gyrB	6793	c.1554T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6797	p.Gly520Ser	missense_variant	1.0	levofloxacin
gyrB	6797	p.Gly520Ser	missense_variant	1.0	moxifloxacin
gyrB	6811	c.1572C>T	synonymous_variant	1.0	levofloxacin
gyrB	6811	c.1572C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6841	c.1602T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6841	c.1602T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6844	c.-458T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6844	c.-458T>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6856	c.1617T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6856	c.1617T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6869	c.-433T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6869	c.-433T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6872	c.1633_1635delTTGinsCC	frameshift_variant&missense_variant	1.0	levofloxacin	Uncertain significance
gyrB	6872	c.1633_1635delTTGinsCC	frameshift_variant&missense_variant	1.0	moxifloxacin
gyrA	6877	c.-425G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6877	c.-425G>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6878	c.1639T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6878	c.1639T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6881	c.1642T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6881	c.1642T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6889	c.-413G>T	upstream_gene_variant	1.0	levofloxacin
gyrA	6889	c.-413G>T	upstream_gene_variant	1.0	moxifloxacin
gyrA	6904	c.-398C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6904	c.-398C>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6905	c.1666_1668delATCinsGG	frameshift_variant&missense_variant	1.0	levofloxacin	Uncertain significance
gyrB	6905	c.1666_1668delATCinsGG	frameshift_variant&missense_variant	1.0	moxifloxacin
gyrB	6911	p.Asn558His	missense_variant	1.0	levofloxacin
gyrB	6911	p.Asn558His	missense_variant	1.0	moxifloxacin
gyrA	6916	c.-386G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6916	c.-386G>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6919	c.1680T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6919	c.1680T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6925	c.-377T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6925	c.-377T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6931	c.1692A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6931	c.1692A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6934	c.-368A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6934	c.-368A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6949	c.-353A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6949	c.-353A>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6962	c.1725_1726insGGC	conservative_inframe_insertion	0.62	levofloxacin
gyrB	6962	c.1725_1726insGGC	conservative_inframe_insertion	0.62	moxifloxacin
gyrB	6966	p.Ser576Asn	missense_variant	0.94	levofloxacin
gyrB	6966	p.Ser576Asn	missense_variant	0.94	moxifloxacin
gyrB	6971	c.1732_1734delCCGinsGC	frameshift_variant&missense_variant	0.94	levofloxacin	Uncertain significance
gyrB	6971	c.1732_1734delCCGinsGC	frameshift_variant&missense_variant	0.94	moxifloxacin
gyrA	6982	c.-320A>C	upstream_gene_variant	0.95	levofloxacin
gyrA	6982	c.-320A>C	upstream_gene_variant	0.95	moxifloxacin
gyrA	6997	c.-305G>A	upstream_gene_variant	0.95	levofloxacin
gyrA	6997	c.-305G>A	upstream_gene_variant	0.95	moxifloxacin
gyrB	7012	c.1773G>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrB	7012	c.1773G>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	7015	c.-287G>A	upstream_gene_variant	0.95	levofloxacin
gyrA	7015	c.-287G>A	upstream_gene_variant	0.95	moxifloxacin
gyrA	7018	c.-284G>C	upstream_gene_variant	0.95	levofloxacin
gyrA	7018	c.-284G>C	upstream_gene_variant	0.95	moxifloxacin
gyrB	7021	c.1782_1784delGCTinsC	frameshift_variant&synonymous_variant	0.95	levofloxacin	Uncertain significance
gyrB	7021	c.1782_1784delGCTinsC	frameshift_variant&synonymous_variant	0.95	moxifloxacin
gyrA	7024	c.-278G>A	upstream_gene_variant	0.95	levofloxacin
gyrA	7024	c.-278G>A	upstream_gene_variant	0.95	moxifloxacin
gyrB	7027	c.1788_1789insCC	frameshift_variant	0.95	levofloxacin	Uncertain significance
gyrB	7027	c.1788_1789insCC	frameshift_variant	0.95	moxifloxacin
gyrA	7033	c.-269G>C	upstream_gene_variant	0.96	levofloxacin
gyrA	7033	c.-269G>C	upstream_gene_variant	0.96	moxifloxacin
gyrB	7047	p.Lys603Met	missense_variant	0.92	levofloxacin
gyrB	7047	p.Lys603Met	missense_variant	0.92	moxifloxacin
gyrB	7051	p.Glu604Asp	missense_variant	0.96	levofloxacin
gyrB	7051	p.Glu604Asp	missense_variant	0.96	moxifloxacin
gyrA	7066	c.-236G>C	upstream_gene_variant	0.96	levofloxacin
gyrA	7066	c.-236G>C	upstream_gene_variant	0.96	moxifloxacin
gyrA	7078	c.-224A>C	upstream_gene_variant	0.93	levofloxacin
gyrA	7078	c.-224A>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	7084	c.-218A>G	upstream_gene_variant	0.88	levofloxacin
gyrA	7084	c.-218A>G	upstream_gene_variant	0.88	moxifloxacin
gyrB	7093	c.1854T>C	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrB	7093	c.1854T>C	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	7114	c.-188C>G	upstream_gene_variant	0.9	levofloxacin
gyrA	7114	c.-188C>G	upstream_gene_variant	0.9	moxifloxacin
gyrA	7313	c.12G>C	synonymous_variant	0.94	levofloxacin
gyrA	7313	c.12G>C	synonymous_variant	0.94	moxifloxacin
gyrA	7317	c.16T>C	synonymous_variant	0.94	levofloxacin
gyrA	7317	c.16T>C	synonymous_variant	0.94	moxifloxacin
gyrA	7322	c.21G>A	synonymous_variant	0.94	levofloxacin
gyrA	7322	c.21G>A	synonymous_variant	0.94	moxifloxacin
gyrA	7325	c.24delTinsCGGA	conservative_inframe_insertion&synonymous_variant	0.94	levofloxacin
gyrA	7325	c.24delTinsCGGA	conservative_inframe_insertion&synonymous_variant	0.94	moxifloxacin
gyrA	7335	c.34_36delCTCinsGA	frameshift_variant&missense_variant	0.96	levofloxacin
gyrA	7335	c.34_36delCTCinsGA	frameshift_variant&missense_variant	0.96	moxifloxacin
gyrA	7355	c.54T>C	synonymous_variant	0.96	levofloxacin
gyrA	7355	c.54T>C	synonymous_variant	0.96	moxifloxacin
gyrA	7362	p.Glu21Gln	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7362	p.Glu21Gln	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7394	c.93T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7394	c.93T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7397	c.96G>C	synonymous_variant	0.97	levofloxacin
gyrA	7397	c.96G>C	synonymous_variant	0.97	moxifloxacin
gyrA	7412	c.111C>G	synonymous_variant	0.98	levofloxacin
gyrA	7412	c.111C>G	synonymous_variant	0.98	moxifloxacin
gyrA	7418	c.117C>T	synonymous_variant	0.98	levofloxacin
gyrA	7418	c.117C>T	synonymous_variant	0.98	moxifloxacin
gyrA	7421	c.120G>A	synonymous_variant	0.98	levofloxacin
gyrA	7421	c.120G>A	synonymous_variant	0.98	moxifloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.98	levofloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.98	moxifloxacin
gyrA	7436	c.135C>T	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	7436	c.135C>T	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	7442	c.141G>T	synonymous_variant	0.98	levofloxacin
gyrA	7442	c.141G>T	synonymous_variant	0.98	moxifloxacin
gyrA	7451	c.150C>G	synonymous_variant	0.98	levofloxacin
gyrA	7451	c.150C>G	synonymous_variant	0.98	moxifloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.99	levofloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.99	moxifloxacin
gyrA	7463	c.162G>C	synonymous_variant	0.99	levofloxacin
gyrA	7463	c.162G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7472	c.171T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7472	c.171T>C	synonymous_variant	0.99	moxifloxacin
gyrA	7475	c.174A>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7475	c.174A>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7480	p.Phe60Tyr	missense_variant	0.99	levofloxacin
gyrA	7480	p.Phe60Tyr	missense_variant	0.99	moxifloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.99	levofloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.99	moxifloxacin
gyrA	7490	c.189C>G	synonymous_variant	0.99	levofloxacin
gyrA	7490	c.189C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7496	c.195C>T	synonymous_variant	0.99	levofloxacin
gyrA	7496	c.195C>T	synonymous_variant	0.99	moxifloxacin
gyrA	7499	c.198G>C	synonymous_variant	0.99	levofloxacin
gyrA	7499	c.198G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7514	c.213C>G	synonymous_variant	0.99	levofloxacin
gyrA	7514	c.213C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7517	c.216G>A	synonymous_variant	0.99	levofloxacin
gyrA	7517	c.216G>A	synonymous_variant	0.99	moxifloxacin
gyrA	7520	c.219G>C	synonymous_variant	0.99	levofloxacin
gyrA	7520	c.219G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7523	c.222C>A	synonymous_variant	0.99	levofloxacin
gyrA	7523	c.222C>A	synonymous_variant	0.99	moxifloxacin
gyrA	7541	c.240C>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7547	c.246C>T	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7547	c.246C>T	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7571	c.270G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7571	c.270G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7585	p.Ser95Thr	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7585	p.Ser95Thr	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7592	c.291G>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7592	c.291G>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7595	c.294C>G	synonymous_variant	0.99	levofloxacin
gyrA	7595	c.294C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7607	c.306C>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7607	c.306C>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7619	c.318C>T	synonymous_variant	0.99	levofloxacin
gyrA	7619	c.318C>T	synonymous_variant	0.99	moxifloxacin
gyrA	7631	c.330G>C	synonymous_variant	1.0	levofloxacin
gyrA	7631	c.330G>C	synonymous_variant	1.0	moxifloxacin
gyrA	7652	c.351C>T	synonymous_variant	1.0	levofloxacin
gyrA	7652	c.351C>T	synonymous_variant	1.0	moxifloxacin
gyrA	7658	c.357A>G	synonymous_variant	1.0	levofloxacin
gyrA	7658	c.357A>G	synonymous_variant	1.0	moxifloxacin
gyrA	7670	c.369A>C	synonymous_variant	0.99	levofloxacin
gyrA	7670	c.369A>C	synonymous_variant	0.99	moxifloxacin
gyrA	7671	p.Pro124Ala	missense_variant	0.99	levofloxacin
gyrA	7671	p.Pro124Ala	missense_variant	0.99	moxifloxacin
gyrA	7676	c.375G>C	synonymous_variant	0.99	levofloxacin
gyrA	7676	c.375G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7679	c.378G>C	synonymous_variant	0.99	levofloxacin
gyrA	7679	c.378G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7683	c.382_384delAGGinsCT	frameshift_variant&missense_variant	0.99	levofloxacin
gyrA	7683	c.382_384delAGGinsCT	frameshift_variant&missense_variant	0.99	moxifloxacin
gyrA	7694	c.393A>G	synonymous_variant	1.0	levofloxacin
gyrA	7694	c.393A>G	synonymous_variant	1.0	moxifloxacin
gyrA	7710	c.409T>C	synonymous_variant	1.0	levofloxacin
gyrA	7710	c.409T>C	synonymous_variant	1.0	moxifloxacin
gyrA	7715	c.414G>C	synonymous_variant	1.0	levofloxacin
gyrA	7715	c.414G>C	synonymous_variant	1.0	moxifloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.99	levofloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.99	moxifloxacin
gyrA	7745	c.444G>A	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7745	c.444G>A	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7758	p.Ile153Val	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	7758	p.Ile153Val	missense_variant	1.0	moxifloxacin
gyrA	7763	c.462T>G	synonymous_variant	1.0	levofloxacin
gyrA	7763	c.462T>G	synonymous_variant	1.0	moxifloxacin
gyrA	7797	c.496_498delCTAinsTG	frameshift_variant&stop_gained	1.0	levofloxacin
gyrA	7797	c.496_498delCTAinsTG	frameshift_variant&stop_gained	1.0	moxifloxacin
gyrA	7802	c.501C>G	synonymous_variant	1.0	levofloxacin
gyrA	7802	c.501C>G	synonymous_variant	1.0	moxifloxacin
gyrA	7814	c.513C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7814	c.513C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7832	c.531G>T	synonymous_variant	0.99	levofloxacin
gyrA	7832	c.531G>T	synonymous_variant	0.99	moxifloxacin
gyrA	7835	c.534A>C	synonymous_variant	0.99	levofloxacin
gyrA	7835	c.534A>C	synonymous_variant	0.99	moxifloxacin
gyrA	7841	c.540C>T	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7841	c.540C>T	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7847	c.546G>A	synonymous_variant	0.99	levofloxacin
gyrA	7847	c.546G>A	synonymous_variant	0.99	moxifloxacin
gyrA	7853	c.552C>T	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7853	c.552C>T	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7859	c.558A>G	synonymous_variant	0.98	levofloxacin
gyrA	7859	c.558A>G	synonymous_variant	0.98	moxifloxacin
gyrA	7865	c.564T>C	synonymous_variant	0.98	levofloxacin
gyrA	7865	c.564T>C	synonymous_variant	0.98	moxifloxacin
gyrA	7886	c.585T>C	synonymous_variant	0.97	levofloxacin
gyrA	7886	c.585T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7889	c.588G>A	synonymous_variant	0.97	levofloxacin
gyrA	7889	c.588G>A	synonymous_variant	0.97	moxifloxacin
gyrA	7892	c.591G>C	synonymous_variant	0.97	levofloxacin
gyrA	7892	c.591G>C	synonymous_variant	0.97	moxifloxacin
gyrA	7898	p.Asp199Glu	missense_variant	0.97	levofloxacin
gyrA	7898	p.Asp199Glu	missense_variant	0.97	moxifloxacin
gyrA	7911	p.Ala204Cys	missense_variant	0.96	levofloxacin
gyrA	7911	p.Ala204Cys	missense_variant	0.96	moxifloxacin
gyrA	7919	p.Glu206Asp	missense_variant	0.96	levofloxacin
gyrA	7919	p.Glu206Asp	missense_variant	0.96	moxifloxacin
gyrA	7922	c.621T>C	synonymous_variant	0.96	levofloxacin
gyrA	7922	c.621T>C	synonymous_variant	0.96	moxifloxacin
gyrA	7928	p.Asp209Glu	missense_variant	0.96	levofloxacin
gyrA	7928	p.Asp209Glu	missense_variant	0.96	moxifloxacin
gyrA	7941	p.Glu214Thr	missense_variant	0.92	levofloxacin
gyrA	7941	p.Glu214Thr	missense_variant	0.92	moxifloxacin
gyrA	7951	p.Ala217Glu	missense_variant	0.92	levofloxacin
gyrA	7951	p.Ala217Glu	missense_variant	0.92	moxifloxacin
gyrA	7958	c.657C>G	synonymous_variant	0.92	levofloxacin
gyrA	7958	c.657C>G	synonymous_variant	0.92	moxifloxacin
gyrA	7963	p.Gly221Glu	missense_variant	0.92	levofloxacin
gyrA	7963	p.Gly221Glu	missense_variant	0.92	moxifloxacin
gyrA	7970	c.669T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	7970	c.669T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	7973	c.672A>G	synonymous_variant	0.92	levofloxacin
gyrA	7973	c.672A>G	synonymous_variant	0.92	moxifloxacin
gyrA	7979	c.678G>C	synonymous_variant	0.92	levofloxacin
gyrA	7979	c.678G>C	synonymous_variant	0.92	moxifloxacin
gyrA	7988	c.687G>C	synonymous_variant	0.89	levofloxacin	Not assoc w R - Interim
gyrA	7988	c.687G>C	synonymous_variant	0.89	moxifloxacin	Not assoc w R - Interim
gyrA	7992	p.Ala231Ser	missense_variant	0.84	levofloxacin
gyrA	7992	p.Ala231Ser	missense_variant	0.84	moxifloxacin
gyrA	7997	c.696A>C	synonymous_variant	0.84	levofloxacin
gyrA	7997	c.696A>C	synonymous_variant	0.84	moxifloxacin
gyrA	8009	c.708A>T	synonymous_variant	0.79	levofloxacin
gyrA	8009	c.708A>T	synonymous_variant	0.79	moxifloxacin
gyrA	8012	c.711C>G	synonymous_variant	0.67	levofloxacin
gyrA	8012	c.711C>G	synonymous_variant	0.67	moxifloxacin
gyrA	8247	p.Ile316Val	missense_variant	0.94	levofloxacin
gyrA	8247	p.Ile316Val	missense_variant	0.94	moxifloxacin
gyrA	8264	c.963T>C	synonymous_variant	0.94	levofloxacin
gyrA	8264	c.963T>C	synonymous_variant	0.94	moxifloxacin
gyrA	8283	c.982_984delATCinsCG	frameshift_variant&missense_variant	0.93	levofloxacin
gyrA	8283	c.982_984delATCinsCG	frameshift_variant&missense_variant	0.93	moxifloxacin
gyrA	8288	c.987T>C	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	8288	c.987T>C	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.91	moxifloxacin	Not assoc w R - Interim
gyrA	8310	c.1009C>T	synonymous_variant	0.91	levofloxacin
gyrA	8310	c.1009C>T	synonymous_variant	0.91	moxifloxacin
gyrA	8324	c.1023T>C	synonymous_variant	0.93	levofloxacin
gyrA	8324	c.1023T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8339	c.1038A>C	synonymous_variant	0.93	levofloxacin
gyrA	8339	c.1038A>C	synonymous_variant	0.93	moxifloxacin
gyrA	8340	p.Ala347Ser	missense_variant	0.93	levofloxacin	Uncertain significance
gyrA	8340	p.Ala347Ser	missense_variant	0.93	moxifloxacin	Uncertain significance
gyrA	8366	c.1065G>C	synonymous_variant	0.95	levofloxacin
gyrA	8366	c.1065G>C	synonymous_variant	0.95	moxifloxacin
gyrA	8378	c.1077C>T	synonymous_variant	0.95	levofloxacin
gyrA	8378	c.1077C>T	synonymous_variant	0.95	moxifloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.95	levofloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.95	moxifloxacin
gyrA	8393	c.1092T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8393	c.1092T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	8471	c.1170T>C	synonymous_variant	0.95	levofloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.95	moxifloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.96	levofloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.96	moxifloxacin
gyrA	8486	c.1185T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8486	c.1185T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8492	c.1191G>T	synonymous_variant	0.97	levofloxacin
gyrA	8492	c.1191G>T	synonymous_variant	0.97	moxifloxacin
gyrA	8498	c.1197C>T	synonymous_variant	0.97	levofloxacin
gyrA	8498	c.1197C>T	synonymous_variant	0.97	moxifloxacin
gyrA	8504	c.1203G>C	synonymous_variant	0.97	levofloxacin
gyrA	8504	c.1203G>C	synonymous_variant	0.97	moxifloxacin
gyrA	8513	c.1212C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8513	c.1212C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8516	c.1215T>C	synonymous_variant	0.97	levofloxacin
gyrA	8516	c.1215T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8519	c.1218A>C	synonymous_variant	0.97	levofloxacin
gyrA	8519	c.1218A>C	synonymous_variant	0.97	moxifloxacin
gyrA	8522	c.1221G>C	synonymous_variant	0.97	levofloxacin
gyrA	8522	c.1221G>C	synonymous_variant	0.97	moxifloxacin
gyrA	8531	c.1230G>A	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrA	8531	c.1230G>A	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	8535	p.Glu412Gln	missense_variant	0.95	levofloxacin
gyrA	8535	p.Glu412Gln	missense_variant	0.95	moxifloxacin
gyrA	8546	c.1245T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	8552	c.1251C>T	synonymous_variant	0.95	levofloxacin
gyrA	8552	c.1251C>T	synonymous_variant	0.95	moxifloxacin
gyrA	8585	c.1284C>T	synonymous_variant	0.98	levofloxacin
gyrA	8585	c.1284C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8588	p.Glu429Asp	missense_variant	0.98	levofloxacin
gyrA	8588	p.Glu429Asp	missense_variant	0.98	moxifloxacin
gyrA	8591	c.1290C>T	synonymous_variant	0.98	levofloxacin
gyrA	8591	c.1290C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8597	c.1296C>A	synonymous_variant	0.98	levofloxacin
gyrA	8597	c.1296C>A	synonymous_variant	0.98	moxifloxacin
gyrA	8600	c.1299G>A	synonymous_variant	0.98	levofloxacin
gyrA	8600	c.1299G>A	synonymous_variant	0.98	moxifloxacin
gyrA	8603	c.1302A>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8603	c.1302A>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8619	c.1318T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8619	c.1318T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>C	synonymous_variant	0.95	levofloxacin
gyrA	8624	c.1323G>C	synonymous_variant	0.95	moxifloxacin
gyrA	8627	c.1326C>G	synonymous_variant	0.94	levofloxacin
gyrA	8627	c.1326C>G	synonymous_variant	0.94	moxifloxacin
gyrA	8633	c.1332C>G	synonymous_variant	0.91	levofloxacin
gyrA	8633	c.1332C>G	synonymous_variant	0.91	moxifloxacin
gyrA	8636	c.1335A>G	synonymous_variant	0.91	levofloxacin
gyrA	8636	c.1335A>G	synonymous_variant	0.91	moxifloxacin
gyrA	8649	p.Arg450Lys	missense_variant	0.9	levofloxacin
gyrA	8649	p.Arg450Lys	missense_variant	0.9	moxifloxacin
gyrA	8660	c.1359C>T	synonymous_variant	0.9	levofloxacin	Not assoc w R - Interim
gyrA	8660	c.1359C>T	synonymous_variant	0.9	moxifloxacin	Not assoc w R - Interim
gyrA	8663	p.Asp454Glu	missense_variant	0.9	levofloxacin
gyrA	8663	p.Asp454Glu	missense_variant	0.9	moxifloxacin
gyrA	8664	c.1363C>T	synonymous_variant	0.9	levofloxacin
gyrA	8664	c.1363C>T	synonymous_variant	0.9	moxifloxacin
gyrA	8672	c.1371A>G	synonymous_variant	0.9	levofloxacin	Not assoc w R - Interim
gyrA	8672	c.1371A>G	synonymous_variant	0.9	moxifloxacin	Not assoc w R - Interim
gyrA	8786	c.1485T>C	synonymous_variant	1.0	levofloxacin
gyrA	8786	c.1485T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8792	c.1491G>A	synonymous_variant	1.0	levofloxacin
gyrA	8792	c.1491G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8801	c.1500G>C	synonymous_variant	1.0	levofloxacin
gyrA	8801	c.1500G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8810	c.1509A>G	synonymous_variant	1.0	levofloxacin
gyrA	8810	c.1509A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8817	p.Ser506Ala	missense_variant	1.0	levofloxacin
gyrA	8817	p.Ser506Ala	missense_variant	1.0	moxifloxacin
gyrA	8825	c.1524G>A	synonymous_variant	0.99	levofloxacin
gyrA	8825	c.1524G>A	synonymous_variant	0.99	moxifloxacin
gyrA	8829	c.1528T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8829	c.1528T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8840	c.1539C>T	synonymous_variant	0.99	levofloxacin
gyrA	8840	c.1539C>T	synonymous_variant	0.99	moxifloxacin
gyrA	8849	c.1548C>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8849	c.1548C>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8852	c.1551T>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8852	c.1551T>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8858	c.1557T>C	synonymous_variant	0.99	levofloxacin
gyrA	8858	c.1557T>C	synonymous_variant	0.99	moxifloxacin
gyrA	8867	c.1566A>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8867	c.1566A>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8915	c.1614A>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8915	c.1614A>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8924	c.1623C>T	synonymous_variant	0.98	levofloxacin
gyrA	8924	c.1623C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8930	c.1629C>T	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8930	c.1629C>T	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8933	c.1632G>A	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8933	c.1632G>A	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8939	c.1638T>C	synonymous_variant	0.98	levofloxacin
gyrA	8939	c.1638T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.98	levofloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.98	moxifloxacin
gyrA	8945	c.1644G>C	synonymous_variant	0.98	levofloxacin
gyrA	8945	c.1644G>C	synonymous_variant	0.98	moxifloxacin
gyrA	8946	c.1645_1647delTTGinsCC	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8946	c.1645_1647delTTGinsCC	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8981	c.1680G>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8981	c.1680G>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8990	c.1689C>G	synonymous_variant	0.99	levofloxacin
gyrA	8990	c.1689C>G	synonymous_variant	0.99	moxifloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.99	levofloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.99	moxifloxacin
gyrA	8998	p.Leu566Trp	missense_variant	0.99	levofloxacin	Uncertain significance
gyrA	8998	p.Leu566Trp	missense_variant	0.99	moxifloxacin	Uncertain significance
gyrA	9008	c.1707C>T	synonymous_variant	0.99	levofloxacin
gyrA	9008	c.1707C>T	synonymous_variant	0.99	moxifloxacin
gyrA	9017	c.1716C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9017	c.1716C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9029	c.1728T>G	synonymous_variant	1.0	levofloxacin
gyrA	9029	c.1728T>G	synonymous_variant	1.0	moxifloxacin
gyrA	9032	c.1731T>C	synonymous_variant	1.0	levofloxacin
gyrA	9032	c.1731T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9035	c.1734G>A	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9035	c.1734G>A	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9056	c.1755C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9056	c.1755C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9062	c.1761C>G	synonymous_variant	0.97	levofloxacin
gyrA	9062	c.1761C>G	synonymous_variant	0.97	moxifloxacin
gyrA	9064	p.Ser588Leu	missense_variant	0.99	levofloxacin
gyrA	9064	p.Ser588Leu	missense_variant	0.99	moxifloxacin
gyrA	9068	c.1767G>C	synonymous_variant	0.99	levofloxacin
gyrA	9068	c.1767G>C	synonymous_variant	0.99	moxifloxacin
gyrA	9071	c.1770G>C	synonymous_variant	0.99	levofloxacin
gyrA	9071	c.1770G>C	synonymous_variant	0.99	moxifloxacin
gyrA	9074	c.1773G>A	synonymous_variant	0.99	levofloxacin
gyrA	9074	c.1773G>A	synonymous_variant	0.99	moxifloxacin
gyrA	9080	c.1779G>C	synonymous_variant	0.99	levofloxacin
gyrA	9080	c.1779G>C	synonymous_variant	0.99	moxifloxacin
gyrA	9089	c.1788G>C	synonymous_variant	0.99	levofloxacin
gyrA	9089	c.1788G>C	synonymous_variant	0.99	moxifloxacin
gyrA	9099	c.1798_1800delTTAinsCG	frameshift_variant&missense_variant	0.99	levofloxacin
gyrA	9099	c.1798_1800delTTAinsCG	frameshift_variant&missense_variant	0.99	moxifloxacin
gyrA	9116	c.1815G>A	synonymous_variant	0.99	levofloxacin
gyrA	9116	c.1815G>A	synonymous_variant	0.99	moxifloxacin
gyrA	9119	c.1818A>G	synonymous_variant	0.99	levofloxacin
gyrA	9119	c.1818A>G	synonymous_variant	0.99	moxifloxacin
gyrA	9128	c.1827C>T	synonymous_variant	0.98	levofloxacin
gyrA	9128	c.1827C>T	synonymous_variant	0.98	moxifloxacin
gyrA	9143	c.1842T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R
gyrA	9143	c.1842T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R
gyrA	9144	p.Arg615Lys	missense_variant	0.97	levofloxacin
gyrA	9144	p.Arg615Lys	missense_variant	0.97	moxifloxacin
gyrA	9147	p.Gly616Ser	missense_variant	0.97	levofloxacin
gyrA	9147	p.Gly616Ser	missense_variant	0.97	moxifloxacin
gyrA	9153	p.Thr618Glu	missense_variant	0.94	levofloxacin
gyrA	9153	p.Thr618Glu	missense_variant	0.94	moxifloxacin
gyrA	9161	c.1860C>G	synonymous_variant	0.95	levofloxacin
gyrA	9161	c.1860C>G	synonymous_variant	0.95	moxifloxacin
gyrA	9167	c.1866C>T	synonymous_variant	0.95	levofloxacin
gyrA	9167	c.1866C>T	synonymous_variant	0.95	moxifloxacin
gyrA	9174	c.1873C>T	synonymous_variant	0.96	levofloxacin
gyrA	9174	c.1873C>T	synonymous_variant	0.96	moxifloxacin
gyrA	9182	c.1881T>C	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	9182	c.1881T>C	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	9191	c.1890G>T	synonymous_variant	0.97	levofloxacin
gyrA	9191	c.1890G>T	synonymous_variant	0.97	moxifloxacin
gyrA	9197	c.1896G>C	synonymous_variant	0.97	levofloxacin
gyrA	9197	c.1896G>C	synonymous_variant	0.97	moxifloxacin
gyrA	9200	c.1899A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	9200	c.1899A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	9230	c.1929T>C	synonymous_variant	0.98	levofloxacin
gyrA	9230	c.1929T>C	synonymous_variant	0.98	moxifloxacin
gyrA	9233	c.1932C>G	synonymous_variant	0.99	levofloxacin
gyrA	9233	c.1932C>G	synonymous_variant	0.99	moxifloxacin
gyrA	9236	c.1935G>C	synonymous_variant	0.99	levofloxacin
gyrA	9236	c.1935G>C	synonymous_variant	0.99	moxifloxacin
gyrA	9242	c.1941A>C	synonymous_variant	0.99	levofloxacin
gyrA	9242	c.1941A>C	synonymous_variant	0.99	moxifloxacin
gyrA	9245	c.1944C>T	synonymous_variant	0.99	levofloxacin
gyrA	9245	c.1944C>T	synonymous_variant	0.99	moxifloxacin
gyrA	9248	c.1947G>C	synonymous_variant	0.99	levofloxacin
gyrA	9248	c.1947G>C	synonymous_variant	0.99	moxifloxacin
gyrA	9252	p.Val651Ile	missense_variant	0.99	levofloxacin	Uncertain significance
gyrA	9252	p.Val651Ile	missense_variant	0.99	moxifloxacin	Uncertain significance
gyrA	9267	p.Asn656Gly	missense_variant	0.99	levofloxacin
gyrA	9267	p.Asn656Gly	missense_variant	0.99	moxifloxacin
gyrA	9275	c.1974G>A	synonymous_variant	0.99	levofloxacin
gyrA	9275	c.1974G>A	synonymous_variant	0.99	moxifloxacin
gyrA	9281	c.1980C>G	synonymous_variant	0.99	levofloxacin
gyrA	9281	c.1980C>G	synonymous_variant	0.99	moxifloxacin
gyrA	9284	c.1983T>C	synonymous_variant	0.99	levofloxacin
gyrA	9284	c.1983T>C	synonymous_variant	0.99	moxifloxacin
gyrA	9296	c.1995T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	9296	c.1995T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	9299	c.1998G>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	9299	c.1998G>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	9304	p.Gly668Glu	missense_variant	0.99	levofloxacin
gyrA	9304	p.Gly668Glu	missense_variant	0.99	moxifloxacin
gyrA	9308	p.Asp669Glu	missense_variant	1.0	levofloxacin
gyrA	9308	p.Asp669Glu	missense_variant	1.0	moxifloxacin
gyrA	9323	c.2022C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9323	c.2022C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9329	c.2028C>G	synonymous_variant	1.0	levofloxacin
gyrA	9329	c.2028C>G	synonymous_variant	1.0	moxifloxacin
gyrA	9335	c.2034G>T	synonymous_variant	1.0	levofloxacin
gyrA	9335	c.2034G>T	synonymous_variant	1.0	moxifloxacin
gyrA	9345	c.2044A>C	synonymous_variant	1.0	levofloxacin
gyrA	9345	c.2044A>C	synonymous_variant	1.0	moxifloxacin
gyrA	9365	p.Glu688Asp	missense_variant	1.0	levofloxacin
gyrA	9365	p.Glu688Asp	missense_variant	1.0	moxifloxacin
gyrA	9377	c.2076A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9377	c.2076A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9383	c.2082T>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9383	c.2082T>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9386	c.2085T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9386	c.2085T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9395	c.2094G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	9395	c.2094G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	9419	c.2118T>C	synonymous_variant	0.96	levofloxacin
gyrA	9419	c.2118T>C	synonymous_variant	0.96	moxifloxacin
gyrA	9420	p.Ile707Ala	missense_variant	0.96	levofloxacin
gyrA	9420	p.Ile707Ala	missense_variant	0.96	moxifloxacin
gyrA	9425	c.2124C>T	synonymous_variant	0.96	levofloxacin
gyrA	9425	c.2124C>T	synonymous_variant	0.96	moxifloxacin
gyrA	9443	c.2142G>C	synonymous_variant	0.89	levofloxacin	Not assoc w R - Interim
gyrA	9443	c.2142G>C	synonymous_variant	0.89	moxifloxacin	Not assoc w R - Interim
gyrA	9449	c.2148C>G	synonymous_variant	0.87	levofloxacin
gyrA	9449	c.2148C>G	synonymous_variant	0.87	moxifloxacin
gyrA	9452	c.2151G>C	synonymous_variant	0.87	levofloxacin
gyrA	9452	c.2151G>C	synonymous_variant	0.87	moxifloxacin
gyrA	9455	c.2154T>C	synonymous_variant	0.85	levofloxacin
gyrA	9455	c.2154T>C	synonymous_variant	0.85	moxifloxacin
gyrA	9458	c.2157A>G	synonymous_variant	0.85	levofloxacin
gyrA	9458	c.2157A>G	synonymous_variant	0.85	moxifloxacin
gyrA	9460	p.Gly720Asp	missense_variant	0.85	levofloxacin
gyrA	9460	p.Gly720Asp	missense_variant	0.85	moxifloxacin
gyrA	9464	c.2163C>T	synonymous_variant	0.79	levofloxacin
gyrA	9464	c.2163C>T	synonymous_variant	0.79	moxifloxacin
fgd1	491171	p.Ala130Gly	missense_variant	0.93	clofazimine
					pretomanid
					delamanid
fgd1	491191	p.Gly137Arg	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491196	c.414A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491202	c.420G>T	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491203	p.Gln141Glu	missense_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491212	p.Ser144Arg	missense_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491217	c.435T>C	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491223	c.441C>A	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491226	c.444C>G	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491244	c.462T>C	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491248	p.Arg156Lys	missense_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491259	c.477T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491280	c.498C>G	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491283	p.Asp167Glu	missense_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491284	p.Gly168Ser	missense_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491295	c.513C>G	synonymous_variant	0.99	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fgd1	491307	c.525C>G	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491316	c.534C>G	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491328	c.546C>G	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fgd1	491340	c.558C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491345	p.Ala188Val	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491355	c.573C>T	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491364	c.582T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491367	c.585G>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491472	c.690A>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491487	c.705C>T	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491493	c.711C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491496	c.714C>T	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491499	c.717G>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491502	p.Glu240Asp	missense_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491508	c.726A>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491509	c.727T>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491523	c.741G>A	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491526	c.744T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491536	c.754C>T	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491541	c.759G>A	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491547	c.765A>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491550	c.768T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491563	c.781_782delAGinsTC	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491574	c.792C>T	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491601	c.819T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491610	c.828A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491616	c.834A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491628	c.846G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491640	c.858G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491643	c.861G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491652	c.870C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491658	c.876A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	491661	c.879C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491664	c.882C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491667	c.885A>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491673	c.891A>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491676	c.894T>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491686	p.Thr302His	missense_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491709	c.927A>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491712	c.930T>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
mshA	575665	c.318G>C	synonymous_variant	0.79	ethionamide	Not assoc w R - Interim
mshA	575665	c.318G>C	synonymous_variant	0.79	isoniazid	Not assoc w R - Interim
mshA	575689	c.342G>C	synonymous_variant	0.93	ethionamide
mshA	575689	c.342G>C	synonymous_variant	0.93	isoniazid
mshA	575695	c.348C>G	synonymous_variant	0.93	ethionamide
mshA	575695	c.348C>G	synonymous_variant	0.93	isoniazid	Not assoc w R - Interim
mshA	575701	c.354G>A	synonymous_variant	0.93	ethionamide
mshA	575701	c.354G>A	synonymous_variant	0.93	isoniazid
mshA	575704	c.357T>C	synonymous_variant	0.93	ethionamide
mshA	575704	c.357T>C	synonymous_variant	0.93	isoniazid
mshA	575705	c.358_360delTTGinsCC	frameshift_variant&missense_variant	0.93	ethionamide	Uncertain significance
mshA	575705	c.358_360delTTGinsCC	frameshift_variant&missense_variant	0.93	isoniazid	Uncertain significance
mshA	575714	p.Tyr123Asn	missense_variant	0.94	ethionamide
mshA	575714	p.Tyr123Asn	missense_variant	0.94	isoniazid
mshA	575734	c.387T>G	synonymous_variant	0.95	ethionamide
mshA	575734	c.387T>G	synonymous_variant	0.95	isoniazid
mshA	575737	c.390T>C	synonymous_variant	0.96	ethionamide
mshA	575737	c.390T>C	synonymous_variant	0.96	isoniazid
mshA	575746	c.399C>T	synonymous_variant	0.96	ethionamide
mshA	575746	c.399C>T	synonymous_variant	0.96	isoniazid
mshA	575767	c.420G>A	synonymous_variant	0.97	ethionamide
mshA	575767	c.420G>A	synonymous_variant	0.97	isoniazid
mshA	575770	c.423G>C	synonymous_variant	0.97	ethionamide
mshA	575770	c.423G>C	synonymous_variant	0.97	isoniazid
mshA	575772	p.Val142Ala	missense_variant	0.97	ethionamide
mshA	575772	p.Val142Ala	missense_variant	0.97	isoniazid
mshA	575779	c.432A>G	synonymous_variant	0.97	ethionamide
mshA	575779	c.432A>G	synonymous_variant	0.97	isoniazid
mshA	575782	c.435G>C	synonymous_variant	0.97	ethionamide
mshA	575782	c.435G>C	synonymous_variant	0.97	isoniazid
mshA	575785	c.438T>C	synonymous_variant	0.97	ethionamide
mshA	575785	c.438T>C	synonymous_variant	0.97	isoniazid
mshA	575795	p.Ile150Val	missense_variant	0.98	ethionamide
mshA	575795	p.Ile150Val	missense_variant	0.98	isoniazid
mshA	575803	c.456C>T	synonymous_variant	0.98	ethionamide
mshA	575803	c.456C>T	synonymous_variant	0.98	isoniazid	Not assoc w R - Interim
mshA	575840	c.494dupC	frameshift_variant	0.98	ethionamide	Uncertain significance
mshA	575840	c.494dupC	frameshift_variant	0.98	isoniazid	Uncertain significance
mshA	575844	c.498delC	frameshift_variant	0.98	ethionamide	Uncertain significance
mshA	575844	c.498delC	frameshift_variant	0.98	isoniazid	Uncertain significance
mshA	575848	c.501C>T	synonymous_variant	0.97	ethionamide
mshA	575848	c.501C>T	synonymous_variant	0.97	isoniazid
mshA	575851	c.504C>G	synonymous_variant	0.98	ethionamide
mshA	575851	c.504C>G	synonymous_variant	0.98	isoniazid
mshA	575864	c.517T>C	synonymous_variant	0.98	ethionamide
mshA	575864	c.517T>C	synonymous_variant	0.98	isoniazid
mshA	575878	c.531A>G	synonymous_variant	0.97	ethionamide
mshA	575878	c.531A>G	synonymous_variant	0.97	isoniazid
mshA	575884	c.537G>C	synonymous_variant	0.97	ethionamide
mshA	575884	c.537G>C	synonymous_variant	0.97	isoniazid
mshA	575890	c.543C>G	synonymous_variant	0.97	ethionamide
mshA	575890	c.543C>G	synonymous_variant	0.97	isoniazid
mshA	575892	p.Ala182Gly	missense_variant	0.97	ethionamide
mshA	575892	p.Ala182Gly	missense_variant	0.97	isoniazid
mshA	575905	c.558G>C	synonymous_variant	0.96	ethionamide
mshA	575905	c.558G>C	synonymous_variant	0.96	isoniazid
mshA	575908	c.561A>G	synonymous_variant	0.96	ethionamide
mshA	575908	c.561A>G	synonymous_variant	0.96	isoniazid
mshA	575916	p.Asp190Ala	missense_variant	0.96	ethionamide
mshA	575916	p.Asp190Ala	missense_variant	0.96	isoniazid
mshA	575920	c.573C>G	synonymous_variant	0.95	ethionamide
mshA	575920	c.573C>G	synonymous_variant	0.95	isoniazid
mshA	575925	p.Gly193Ala	missense_variant	0.93	ethionamide
mshA	575925	p.Gly193Ala	missense_variant	0.93	isoniazid
mshA	575929	c.582C>G	synonymous_variant	0.93	ethionamide
mshA	575929	c.582C>G	synonymous_variant	0.93	isoniazid
mshA	575932	c.585G>A	synonymous_variant	0.95	ethionamide
mshA	575932	c.585G>A	synonymous_variant	0.95	isoniazid
mshA	575944	c.597T>C	synonymous_variant	0.94	ethionamide
mshA	575944	c.597T>C	synonymous_variant	0.94	isoniazid
mshA	575950	c.603C>T	synonymous_variant	0.92	ethionamide
mshA	575950	c.603C>T	synonymous_variant	0.92	isoniazid
mshA	575953	c.606G>C	synonymous_variant	0.92	ethionamide
mshA	575953	c.606G>C	synonymous_variant	0.92	isoniazid
mshA	575971	c.624C>T	synonymous_variant	0.85	ethionamide
mshA	575971	c.624C>T	synonymous_variant	0.85	isoniazid
mshA	575973	p.Glu209Ala	missense_variant	0.84	ethionamide
mshA	575973	p.Glu209Ala	missense_variant	0.84	isoniazid
mshA	575980	c.633T>C	synonymous_variant	0.84	ethionamide
mshA	575980	c.633T>C	synonymous_variant	0.84	isoniazid
mshA	575984	c.637T>C	synonymous_variant	0.84	ethionamide
mshA	575984	c.637T>C	synonymous_variant	0.84	isoniazid
mshA	576004	c.657T>C	synonymous_variant	0.85	ethionamide
mshA	576004	c.657T>C	synonymous_variant	0.85	isoniazid
ccsA	620307	c.417C>G	synonymous_variant	0.82	capreomycin
					amikacin
					kanamycin
ccsA	620311	p.Leu141Val	missense_variant	0.75	capreomycin
					amikacin
					kanamycin
ccsA	620337	c.447C>G	synonymous_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620340	c.450C>G	synonymous_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620343	c.453G>T	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620349	c.459A>G	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620366	p.Asn159Thr	missense_variant	0.92	capreomycin
					amikacin
					kanamycin
ccsA	620373	c.483C>G	synonymous_variant	0.92	capreomycin
					amikacin
					kanamycin
ccsA	620379	c.489G>C	synonymous_variant	0.92	capreomycin
					amikacin
					kanamycin
ccsA	620385	c.495G>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620388	c.498A>G	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620409	c.519C>G	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620412	c.522T>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620415	c.525T>C	synonymous_variant	0.93	capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
ccsA	620418	c.528G>A	synonymous_variant	0.93	capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
ccsA	620431	p.Leu181Ile	missense_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620436	c.546T>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620439	c.549T>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620445	c.555A>G	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620454	c.564C>G	synonymous_variant	0.9	capreomycin
					amikacin
					kanamycin
ccsA	620460	c.570T>G	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620463	c.573C>G	synonymous_variant	0.85	capreomycin
					amikacin
					kanamycin
ccsA	620598	c.708C>G	synonymous_variant	0.87	capreomycin
					amikacin
					kanamycin
ccsA	620604	c.714C>G	synonymous_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	620607	c.717T>G	synonymous_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	620613	c.723C>T	synonymous_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	620619	c.729G>T	synonymous_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	620625	c.735A>C	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620631	c.741T>C	synonymous_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	620634	c.744C>G	synonymous_variant	0.92	capreomycin
					amikacin
					kanamycin
ccsA	620648	p.Glu253Gly	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620676	c.786C>T	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620691	c.801G>T	synonymous_variant	0.81	capreomycin
					amikacin
					kanamycin
ccsA	620694	c.804C>G	synonymous_variant	0.8	capreomycin
					amikacin
					kanamycin
ccsA	620698	p.Val270Ile	missense_variant	0.8	capreomycin
					amikacin
					kanamycin
ccsA	620703	c.813G>C	synonymous_variant	0.8	capreomycin
					amikacin
					kanamycin
ccsA	620709	c.819G>C	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620712	c.822G>C	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620718	c.828G>C	synonymous_variant	0.83	capreomycin
					amikacin
					kanamycin
hadA	731726	c.-204C>T	upstream_gene_variant	1.0	isoniazid
hadA	731729	c.-201C>T	upstream_gene_variant	1.0	isoniazid
hadA	731747	c.-183T>C	upstream_gene_variant	0.94	isoniazid
hadA	731753	c.-177A>C	upstream_gene_variant	0.94	isoniazid
hadA	731756	c.-174C>T	upstream_gene_variant	0.94	isoniazid
hadA	731774	c.-156T>C	upstream_gene_variant	0.94	isoniazid
hadA	731789	c.-141A>G	upstream_gene_variant	0.94	isoniazid
hadA	731801	c.-129C>T	upstream_gene_variant	0.94	isoniazid
hadA	731810	c.-120G>C	upstream_gene_variant	0.94	isoniazid
hadA	731831	c.-99G>A	upstream_gene_variant	0.94	isoniazid
hadA	731840	c.-90G>C	upstream_gene_variant	0.88	isoniazid
hadA	731843	c.-87T>C	upstream_gene_variant	0.94	isoniazid
hadA	731852	c.-78A>G	upstream_gene_variant	0.94	isoniazid
hadA	731856	c.-74C>G	upstream_gene_variant	0.94	isoniazid
hadA	731859	c.-71G>T	upstream_gene_variant	0.94	isoniazid
nusG	734367	c.114C>G	synonymous_variant	1.0	rifampicin
nusG	734373	c.120G>C	synonymous_variant	1.0	rifampicin
nusG	734383	c.130_131delAGinsTC	synonymous_variant	1.0	rifampicin
nusG	734391	c.138C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734407	c.154_156delGTTinsAC	frameshift_variant&missense_variant	1.0	rifampicin
nusG	734421	c.168A>G	synonymous_variant	1.0	rifampicin
nusG	734439	c.186C>G	synonymous_variant	1.0	rifampicin
nusG	734442	c.189G>A	synonymous_variant	1.0	rifampicin
nusG	734451	c.198G>C	synonymous_variant	1.0	rifampicin
nusG	734454	c.201A>G	synonymous_variant	1.0	rifampicin
nusG	734460	c.207G>C	synonymous_variant	1.0	rifampicin
nusG	734472	c.219T>C	synonymous_variant	1.0	rifampicin
nusG	734475	c.222T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734502	c.249G>A	synonymous_variant	1.0	rifampicin
nusG	734532	c.279A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734541	c.288A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734559	c.306T>C	synonymous_variant	1.0	rifampicin
nusG	734571	c.318C>G	synonymous_variant	1.0	rifampicin
nusG	734580	c.327T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734586	c.333G>T	synonymous_variant	0.98	rifampicin
nusG	734596	c.343T>C	synonymous_variant	1.0	rifampicin
nusG	734614	p.Ala121Ser	missense_variant	1.0	rifampicin
nusG	734794	p.Val181Ile	missense_variant	0.95	rifampicin	Uncertain significance
nusG	734805	c.552C>T	synonymous_variant	0.95	rifampicin
nusG	734814	c.561G>T	synonymous_variant	0.95	rifampicin
nusG	734820	c.567A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
nusG	734826	c.573A>C	synonymous_variant	0.96	rifampicin
nusG	734829	c.576C>A	synonymous_variant	0.96	rifampicin
nusG	734841	c.588G>C	synonymous_variant	0.96	rifampicin
nusG	734847	c.594T>C	synonymous_variant	0.97	rifampicin
nusG	734854	c.601T>C	synonymous_variant	0.94	rifampicin
nusG	734859	c.606G>C	synonymous_variant	0.94	rifampicin
nusG	734863	p.Thr204Ser	missense_variant	0.94	rifampicin
nusG	734886	c.633A>G	synonymous_variant	0.94	rifampicin
nusG	734910	c.657C>G	synonymous_variant	0.93	rifampicin
nusG	734922	c.669C>T	synonymous_variant	0.93	rifampicin
nusG	734928	c.675A>G	synonymous_variant	0.93	rifampicin
nusG	734934	c.681G>A	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
nusG	734937	c.684G>C	synonymous_variant	0.88	rifampicin
rpoB	760076	c.270C>T	synonymous_variant	1.0	rifampicin
rpoB	760091	c.285G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760101	c.295T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760112	c.306T>C	synonymous_variant	0.99	rifampicin
rpoB	760118	c.312T>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	760121	c.315T>G	synonymous_variant	0.99	rifampicin
rpoB	760124	c.318C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	760130	p.Asp108Glu	missense_variant	0.99	rifampicin	Uncertain significance
rpoB	760139	c.333A>C	synonymous_variant	0.99	rifampicin
rpoB	760142	c.336C>G	synonymous_variant	0.99	rifampicin
rpoB	760148	p.Asp114Glu	missense_variant	0.99	rifampicin
rpoB	760155	p.Lys117Arg	missense_variant	0.99	rifampicin
rpoB	760172	c.366G>C	synonymous_variant	0.99	rifampicin
rpoB	760181	c.375T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	760184	c.378A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	760199	c.393C>G	synonymous_variant	0.99	rifampicin
rpoB	760202	c.396G>A	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	760223	c.417T>C	synonymous_variant	0.99	rifampicin
rpoB	760235	c.429T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760283	c.477G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760298	c.492G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760307	c.501T>G	synonymous_variant	1.0	rifampicin
rpoB	760317	c.511_512delAGinsTC	synonymous_variant	1.0	rifampicin
rpoB	760340	c.534G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760354	p.Glu183Ala	missense_variant	0.99	rifampicin
rpoB	760357	p.Thr184Asn	missense_variant	1.0	rifampicin
rpoB	760361	c.555T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760376	p.Asp190Glu	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	760389	c.583_585delAGCinsTCG	synonymous_variant	1.0	rifampicin
rpoB	760394	c.588C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760407	p.Ser201Gly	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	760412	c.606C>T	synonymous_variant	1.0	rifampicin
rpoB	760418	c.612G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760424	c.618C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760430	c.624T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760449	p.Thr215Leu	missense_variant	0.97	rifampicin
rpoB	760460	c.654G>T	synonymous_variant	0.98	rifampicin
rpoB	760463	c.657C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760475	c.669A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760481	c.675G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760484	c.678A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760494	c.688_690delGTGinsAC	frameshift_variant&missense_variant	0.99	rifampicin
rpoB	760514	c.708C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760521	c.715_716delAGinsTC	synonymous_variant	0.96	rifampicin
rpoB	760532	c.726T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760533	p.Val243Arg	missense_variant	0.95	rifampicin
rpoB	760538	c.732G>A	synonymous_variant	0.95	rifampicin
rpoB	760541	c.735G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760547	c.741G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760563	p.Arg253Met	missense_variant	0.97	rifampicin	Uncertain significance
rpoB	760587	p.Thr261Ala	missense_variant	0.96	rifampicin
rpoB	760591	p.Val262Ala	missense_variant	0.97	rifampicin
rpoB	760593	p.Gly263Ser	missense_variant	0.97	rifampicin
rpoB	760596	p.Thr264Pro	missense_variant	0.97	rifampicin
rpoB	760611	c.805T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760634	c.828T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760649	c.843G>C	synonymous_variant	0.93	rifampicin
rpoB	760655	c.849A>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760658	c.852G>A	synonymous_variant	0.94	rifampicin
rpoB	760661	c.855A>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760670	c.864G>T	synonymous_variant	0.95	rifampicin
rpoB	760674	c.868T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760679	c.873A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760683	c.877T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760715	c.909C>G	synonymous_variant	0.86	rifampicin
rpoB	760718	c.912C>G	synonymous_variant	0.84	rifampicin
rpoB	760721	c.915C>G	synonymous_variant	0.82	rifampicin
rpoB	760724	c.918T>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	760730	c.924T>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	760734	p.Val310Ile	missense_variant	0.85	rifampicin
rpoB	760916	c.1110C>G	synonymous_variant	0.98	rifampicin
rpoB	760919	c.1113C>G	synonymous_variant	0.98	rifampicin
rpoB	760925	c.1119T>C	synonymous_variant	0.98	rifampicin
rpoB	760928	c.1122G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	760931	c.1125C>G	synonymous_variant	0.98	rifampicin
rpoB	760934	c.1128C>T	synonymous_variant	0.98	rifampicin
rpoB	760946	c.1140A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	760964	c.1158C>A	synonymous_variant	0.99	rifampicin
rpoB	760965	p.Met387Leu	missense_variant	0.99	rifampicin	Uncertain significance
rpoB	760973	c.1167G>C	synonymous_variant	0.99	rifampicin
rpoB	760979	c.1173G>A	synonymous_variant	0.99	rifampicin
rpoB	760982	c.1176G>T	synonymous_variant	0.99	rifampicin
rpoB	760985	c.1179G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	760988	c.1182C>T	synonymous_variant	0.99	rifampicin
rpoB	760994	c.1188G>A	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761006	c.1200C>T	synonymous_variant	0.99	rifampicin
rpoB	761015	c.1209G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761021	c.1215G>C	synonymous_variant	1.0	rifampicin
rpoB	761027	c.1221A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761036	c.1230G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761037	c.1231T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761051	c.1245G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761054	c.1248G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761096	c.1290G>C	synonymous_variant	1.0	rifampicin
rpoB	761097	c.1291_1292delAGinsTC	synonymous_variant	1.0	rifampicin
rpoB	761102	c.1296A>G	synonymous_variant	1.0	rifampicin
rpoB	761124	c.1318C>T	synonymous_variant	1.0	rifampicin
rpoB	761132	c.1326G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761133	c.1327T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761168	c.1362C>G	synonymous_variant	1.0	rifampicin
rpoB	761171	c.1365C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761180	c.1374A>G	synonymous_variant	1.0	rifampicin
rpoB	761189	c.1383T>G	synonymous_variant	1.0	rifampicin
rpoB	761195	c.1389G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761201	c.1395G>A	synonymous_variant	1.0	rifampicin
rpoB	761204	c.1398C>T	synonymous_variant	1.0	rifampicin
rpoB	761207	c.1401C>T	synonymous_variant	1.0	rifampicin
rpoB	761222	c.1416G>C	synonymous_variant	1.0	rifampicin
rpoB	761240	c.1434C>T	synonymous_variant	1.0	rifampicin
rpoB	761249	c.1443A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761255	c.1449T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761258	c.1452G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761261	c.1455G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761282	c.1476C>A	synonymous_variant	1.0	rifampicin
rpoB	761300	c.1494G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761318	c.1512G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761327	c.1521A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761330	c.1524G>C	synonymous_variant	1.0	rifampicin
rpoB	761345	c.1539G>C	synonymous_variant	1.0	rifampicin
rpoB	761346	p.Val514Asn	missense_variant	0.99	rifampicin
rpoB	761354	c.1548C>T	synonymous_variant	1.0	rifampicin
rpoB	761360	c.1554T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761369	p.Glu521Asp	missense_variant	1.0	rifampicin
rpoB	761374	p.Val523Glu	missense_variant	1.0	rifampicin
rpoB	761408	c.1602G>T	synonymous_variant	0.97	rifampicin
rpoB	761414	c.1608A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761423	c.1617T>C	synonymous_variant	0.95	rifampicin
rpoB	761489	c.1683G>A	synonymous_variant	0.75	rifampicin	Not assoc w R
rpoB	761492	c.1686G>C	synonymous_variant	0.82	rifampicin
rpoB	761502	c.1696_1698delCCCinsTG	frameshift_variant&missense_variant	0.93	rifampicin
rpoB	761510	c.1704T>C	synonymous_variant	0.95	rifampicin
rpoB	761516	c.1710G>C	synonymous_variant	0.96	rifampicin
rpoB	761537	c.1731C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	761561	c.1755C>G	synonymous_variant	0.98	rifampicin
rpoB	761564	c.1758G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	761573	c.1767C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>T	synonymous_variant	0.98	rifampicin
rpoB	761606	c.1800C>G	synonymous_variant	0.99	rifampicin
rpoB	761612	c.1806G>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761615	c.1809A>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761627	c.1821C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761636	c.1830G>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761645	c.1839C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761648	c.1842T>C	synonymous_variant	0.99	rifampicin
rpoB	761657	c.1851C>A	synonymous_variant	0.99	rifampicin
rpoB	761669	c.1863C>T	synonymous_variant	0.98	rifampicin
rpoB	761675	c.1869G>C	synonymous_variant	0.98	rifampicin
rpoB	761687	c.1881C>T	synonymous_variant	0.98	rifampicin
rpoB	761690	c.1884G>C	synonymous_variant	0.99	rifampicin
rpoB	761711	c.1905C>G	synonymous_variant	0.99	rifampicin
rpoB	761712	p.Val636Ile	missense_variant	0.98	rifampicin
rpoB	761723	p.Glu639Asp	missense_variant	0.98	rifampicin	Not assoc w R
rpoB	761724	c.1918_1920delGAAinsAG	frameshift_variant&missense_variant	0.98	rifampicin
rpoB	761728	p.Ser641Thr	missense_variant	0.98	rifampicin
rpoB	761732	c.1926C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	761741	c.1935G>A	synonymous_variant	0.98	rifampicin
rpoB	761750	c.1944G>T	synonymous_variant	0.99	rifampicin
rpoB	761760	p.Ile652Val	missense_variant	0.98	rifampicin
rpoB	761765	c.1959T>G	synonymous_variant	0.98	rifampicin
rpoB	761772	p.His656Ala	missense_variant	0.98	rifampicin
rpoB	761777	c.1971C>T	synonymous_variant	0.98	rifampicin
rpoB	761778	p.Asn658Asp	missense_variant	0.98	rifampicin
rpoB	761791	p.Arg662Gln	missense_variant	0.98	rifampicin
rpoB	761813	c.2007T>C	synonymous_variant	0.99	rifampicin
rpoB	761814	p.Ala670Asn	missense_variant	0.99	rifampicin
rpoB	761834	c.2028T>C	synonymous_variant	0.99	rifampicin
rpoB	761847	c.2041_2043delTGCinsCT	frameshift_variant&missense_variant	0.99	rifampicin
rpoB	761852	c.2046C>G	synonymous_variant	0.99	rifampicin
rpoB	761858	c.2052G>C	synonymous_variant	0.99	rifampicin
rpoB	761864	c.2058G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761868	c.2062_2064delGACinsCG	frameshift_variant&missense_variant	0.99	rifampicin
rpoB	761873	c.2067A>T	synonymous_variant	0.99	rifampicin
rpoB	761885	c.2079T>C	synonymous_variant	0.98	rifampicin
rpoB	761903	c.2097T>A	synonymous_variant	0.99	rifampicin
rpoB	761906	c.2100C>G	synonymous_variant	0.99	rifampicin
rpoB	761912	c.2106T>C	synonymous_variant	0.99	rifampicin
rpoB	761916	p.Asp704Asn	missense_variant	1.0	rifampicin
rpoB	761930	c.2124G>C	synonymous_variant	1.0	rifampicin
rpoB	761948	c.2142G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761954	c.2148C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761969	c.2163G>A	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	761972	c.2166C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762006	c.2200_2202delCGCinsAG	frameshift_variant&missense_variant	1.0	rifampicin
rpoB	762024	p.Val740Thr	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	762029	c.2223C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762053	c.2247T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762062	c.2256T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762101	c.2295C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762114	p.Ile770Val	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	762131	c.2325C>G	synonymous_variant	1.0	rifampicin
rpoB	762134	c.2328C>T	synonymous_variant	1.0	rifampicin
rpoB	762140	c.2334G>C	synonymous_variant	1.0	rifampicin
rpoB	762143	c.2337T>C	synonymous_variant	1.0	rifampicin
rpoB	762149	c.2343G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762158	c.2352G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762167	c.2361T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762176	c.2370T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762185	c.2379G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762212	c.2406G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762236	c.2430G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762254	c.2448T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762257	c.2451C>G	synonymous_variant	1.0	rifampicin
rpoB	762266	c.2460T>C	synonymous_variant	1.0	rifampicin
rpoB	762281	c.2475G>A	synonymous_variant	1.0	rifampicin
rpoB	762284	c.2478G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762293	c.2487T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762314	c.2508C>T	synonymous_variant	1.0	rifampicin
rpoB	762317	c.2511A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762329	c.2523G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762338	c.2532T>C	synonymous_variant	1.0	rifampicin
rpoB	762347	c.2541T>C	synonymous_variant	1.0	rifampicin
rpoB	762362	p.Glu852Asp	missense_variant	1.0	rifampicin
rpoB	762369	c.2563T>C	synonymous_variant	1.0	rifampicin
rpoC	762374	c.-996G>C	upstream_gene_variant	0.99	rifampicin
rpoC	762380	c.-990T>G	upstream_gene_variant	0.99	rifampicin
rpoC	762398	c.-972T>C	upstream_gene_variant	0.99	rifampicin
rpoC	762401	c.-969G>C	upstream_gene_variant	0.99	rifampicin
rpoB	762404	c.2598T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	762407	c.-963G>C	upstream_gene_variant	0.99	rifampicin
rpoB	762410	c.2604T>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762416	c.2610A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	762449	c.-921C>T	upstream_gene_variant	0.99	rifampicin
rpoC	762452	c.-918G>T	upstream_gene_variant	0.99	rifampicin
rpoB	762470	c.2664G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762490	p.Val895Ala	missense_variant	1.0	rifampicin
rpoC	762509	c.-861T>G	upstream_gene_variant	0.95	rifampicin
rpoB	762510	c.2704_2706delGCCinsCG	frameshift_variant&missense_variant	0.95	rifampicin
rpoC	762527	c.-843G>C	upstream_gene_variant	1.0	rifampicin
rpoC	762533	c.-837T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762536	c.-834T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762537	c.-833T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762551	c.-819C>T	upstream_gene_variant	1.0	rifampicin
rpoC	762560	c.-810A>T	upstream_gene_variant	1.0	rifampicin
rpoC	762563	c.-807G>T	upstream_gene_variant	1.0	rifampicin
rpoC	762575	c.-795C>T	upstream_gene_variant	1.0	rifampicin
rpoC	762581	c.-789T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762582	c.-788T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762587	c.-783G>A	upstream_gene_variant	1.0	rifampicin
rpoC	762710	c.-660G>T	upstream_gene_variant	0.93	rifampicin
rpoB	762725	c.2919C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	762728	c.-642C>G	upstream_gene_variant	0.96	rifampicin
rpoB	762730	p.Gln975Arg	missense_variant	0.97	rifampicin
rpoC	762743	c.-627G>A	upstream_gene_variant	0.98	rifampicin
rpoB	762753	c.2947T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	762758	c.-612G>C	upstream_gene_variant	0.98	rifampicin
rpoB	762760	p.Cys985Ser	missense_variant	0.98	rifampicin	Uncertain significance
rpoB	762768	p.Pro988Ala	missense_variant	0.99	rifampicin	Uncertain significance
rpoB	762782	c.2976T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762785	p.Asp993Glu	missense_variant	0.99	rifampicin	Uncertain significance
rpoB	762788	c.2982G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762789	p.Leu995Met	missense_variant	0.99	rifampicin	Uncertain significance
rpoB	762795	p.Asp997Asn	missense_variant	0.99	rifampicin	Uncertain significance
rpoB	762799	p.Ala998Gly	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	762812	c.3006C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762818	c.3012C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	762827	c.-543G>T	upstream_gene_variant	0.99	rifampicin
rpoB	762831	c.3025_3026delAGinsTC	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762836	c.3030C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762857	c.3051C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762860	c.3054G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762917	c.3111C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762920	c.3114C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoB	762929	c.3123G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762995	c.3189G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763031	c.3225T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763034	c.3228C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763040	c.3234C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763050	c.-320C>T	upstream_gene_variant	1.0	rifampicin
rpoB	763053	c.3247T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763058	c.-312C>G	upstream_gene_variant	1.0	rifampicin
rpoB	763070	c.3264T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763076	c.-294C>G	upstream_gene_variant	1.0	rifampicin
rpoB	763085	c.3279C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763094	c.3288G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763115	c.3309T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763127	c.3321G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763136	c.3330C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763142	c.-228C>G	upstream_gene_variant	1.0	rifampicin
rpoC	763148	c.-222G>C	upstream_gene_variant	1.0	rifampicin
rpoC	763169	c.-201A>G	upstream_gene_variant	1.0	rifampicin
rpoC	763193	c.-177C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763202	c.-168A>G	upstream_gene_variant	1.0	rifampicin
rpoB	763203	p.Ser1133Ala	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	763207	p.Ser1134Lys	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	763227	c.3421C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763238	c.3432T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763262	c.-108C>A	upstream_gene_variant	1.0	rifampicin
rpoC	763265	c.-105G>C	upstream_gene_variant	1.0	rifampicin
rpoB	763283	c.3477T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	763304	c.-66A>T	upstream_gene_variant	0.92	rifampicin
rpoC	763351	c.-19T>C	upstream_gene_variant	0.96	rifampicin	Uncertain significance
rpoC	763352	c.-18T>A	upstream_gene_variant	0.97	rifampicin	Uncertain significance
rpoC	763396	c.27A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763408	c.39T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763411	c.42T>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763414	c.45T>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763430	c.61A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763441	c.72C>T	synonymous_variant	0.99	rifampicin
rpoC	763444	c.75T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763447	c.78C>T	synonymous_variant	1.0	rifampicin
rpoC	763456	c.87A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763465	c.96G>A	synonymous_variant	0.99	rifampicin
rpoC	763486	c.117T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763492	c.123G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763528	c.159G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763546	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763594	c.225C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763603	c.234C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763618	c.249C>T	synonymous_variant	1.0	rifampicin
rpoC	763633	c.264T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763657	c.288G>A	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763660	c.291T>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	763666	c.297G>T	synonymous_variant	0.98	rifampicin
rpoC	763669	c.300C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	763696	c.327T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	763702	c.333C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	763708	c.339G>C	synonymous_variant	0.96	rifampicin
rpoC	763709	c.340C>T	synonymous_variant	0.96	rifampicin
rpoC	763714	c.345G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	763717	c.348T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	763732	c.363C>G	synonymous_variant	0.96	rifampicin
rpoC	763735	c.366G>C	synonymous_variant	0.97	rifampicin
rpoC	763744	c.375G>C	synonymous_variant	0.96	rifampicin
rpoC	763747	c.378G>A	synonymous_variant	0.94	rifampicin
rpoC	763765	c.396T>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	763876	p.Glu169Asp	missense_variant	0.94	rifampicin
rpoC	763879	c.510A>G	synonymous_variant	0.96	rifampicin
rpoC	763888	c.519G>C	synonymous_variant	0.96	rifampicin
rpoC	763891	c.522G>C	synonymous_variant	0.96	rifampicin
rpoC	763894	c.525A>G	synonymous_variant	0.96	rifampicin
rpoC	763900	c.531G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763933	c.564C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	763936	c.567C>G	synonymous_variant	0.98	rifampicin
rpoC	763939	c.570G>A	synonymous_variant	0.98	rifampicin
rpoC	763947	p.Ala193Val	missense_variant	0.94	rifampicin	Uncertain significance
rpoC	763951	c.582G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	763978	c.609C>T	synonymous_variant	0.99	rifampicin
rpoC	763987	c.618C>T	synonymous_variant	0.99	rifampicin
rpoC	763991	c.622_624delATCinsCG	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	763996	c.627T>C	synonymous_variant	0.99	rifampicin
rpoC	764002	c.633C>T	synonymous_variant	0.99	rifampicin
rpoC	764005	c.636G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764023	c.654G>C	synonymous_variant	1.0	rifampicin
rpoC	764024	c.655_657delTTGinsCC	frameshift_variant&missense_variant	1.0	rifampicin
rpoC	764029	p.Glu220Asp	missense_variant	1.0	rifampicin
rpoC	764030	p.Asp221Asn	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	764039	p.Ser224Asp	missense_variant	1.0	rifampicin
rpoC	764044	c.675T>C	synonymous_variant	1.0	rifampicin
rpoC	764048	p.Thr227Val	missense_variant	1.0	rifampicin
rpoC	764059	c.690G>T	synonymous_variant	1.0	rifampicin
rpoC	764083	c.714A>G	synonymous_variant	1.0	rifampicin
rpoC	764085	p.Asn239Thr	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	764087	p.Leu240Val	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	764098	c.729A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764101	c.732C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764104	c.735C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764110	c.741C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764140	c.771C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764143	c.774G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764161	c.792G>C	synonymous_variant	1.0	rifampicin
rpoC	764169	p.Asn267Thr	missense_variant	1.0	rifampicin
rpoC	764188	c.819A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764195	p.Ser276Leu	missense_variant	1.0	rifampicin
rpoC	764203	c.834G>C	synonymous_variant	1.0	rifampicin
rpoC	764206	c.837T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764207	p.Val280Ile	missense_variant	0.99	rifampicin
rpoC	764213	p.Arg282Lys	missense_variant	0.99	rifampicin	Uncertain significance
rpoC	764242	c.873C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764245	c.876C>T	synonymous_variant	0.99	rifampicin
rpoC	764254	c.885G>C	synonymous_variant	0.99	rifampicin
rpoC	764257	c.888G>C	synonymous_variant	0.99	rifampicin
rpoC	764266	c.897T>C	synonymous_variant	0.98	rifampicin
rpoC	764269	c.900G>C	synonymous_variant	0.98	rifampicin
rpoC	764272	c.903G>C	synonymous_variant	0.98	rifampicin
rpoC	764278	c.909A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764287	c.918C>T	synonymous_variant	0.98	rifampicin
rpoC	764293	c.924G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764317	c.948C>G	synonymous_variant	0.97	rifampicin
rpoC	764320	c.951C>G	synonymous_variant	0.97	rifampicin
rpoC	764344	c.975C>T	synonymous_variant	0.97	rifampicin
rpoC	764365	c.996C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764368	c.999C>T	synonymous_variant	0.99	rifampicin
rpoC	764371	c.1002G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764377	c.1008C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764380	c.1011G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764387	c.1018_1020delTTGinsCC	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	764405	c.1036A>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764410	c.1041G>C	synonymous_variant	0.99	rifampicin
rpoC	764429	c.1060C>T	synonymous_variant	1.0	rifampicin
rpoC	764434	c.1065A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764435	c.1066_1068delAGGinsCT	frameshift_variant&missense_variant	1.0	rifampicin
rpoC	764446	c.1077T>C	synonymous_variant	1.0	rifampicin
rpoC	764449	c.1080G>C	synonymous_variant	1.0	rifampicin
rpoC	764452	c.1083T>C	synonymous_variant	1.0	rifampicin
rpoC	764455	c.1086G>C	synonymous_variant	1.0	rifampicin
rpoC	764458	c.1089G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764461	c.1092A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764497	c.1128A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764503	c.1134G>C	synonymous_variant	0.99	rifampicin
rpoC	764521	c.1152T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764527	c.1158C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764539	c.1170C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764548	c.1179G>A	synonymous_variant	0.99	rifampicin
rpoC	764566	c.1197C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764573	c.1204_1206delCTTinsTG	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	764576	c.1207_1208delTCinsAG	synonymous_variant	0.99	rifampicin
rpoC	764581	c.1212T>C	synonymous_variant	0.99	rifampicin
rpoC	764611	c.1242G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764626	c.1257C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764656	c.1287C>G	synonymous_variant	0.99	rifampicin
rpoC	764695	c.1326T>C	synonymous_variant	0.99	rifampicin
rpoC	764716	c.1347G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764719	c.1350G>A	synonymous_variant	0.99	rifampicin
rpoC	764746	c.1377G>A	synonymous_variant	0.98	rifampicin
rpoC	764752	c.1383G>T	synonymous_variant	0.98	rifampicin
rpoC	764764	c.1395T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764791	c.1422C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764803	c.1434C>G	synonymous_variant	0.99	rifampicin
rpoC	764815	c.1446A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764824	c.1455T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764827	c.1458G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764851	c.1482C>T	synonymous_variant	0.99	rifampicin
rpoC	764858	c.1489T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764863	c.1494G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764869	c.1500C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764878	c.1509C>G	synonymous_variant	0.99	rifampicin
rpoC	764887	c.1518G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764888	c.1519T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764896	c.1527C>T	synonymous_variant	0.99	rifampicin
rpoC	764911	c.1542A>G	synonymous_variant	0.98	rifampicin
rpoC	764912	p.Met515Gln	missense_variant	0.98	rifampicin	Uncertain significance
rpoC	764948	c.1579T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	764962	c.1593G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764968	c.1599T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765007	c.1638T>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765008	c.1639T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765019	c.1650A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765034	c.1665T>C	synonymous_variant	0.98	rifampicin
rpoC	765040	c.1671T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765041	c.1672T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765047	c.1678T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765052	c.1683C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765053	c.1684_1685delTCinsAG	synonymous_variant	0.97	rifampicin
rpoC	765076	c.1707A>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765079	c.1710T>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765082	c.1713G>T	synonymous_variant	0.97	rifampicin
rpoC	765089	c.1720T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	765100	c.1731G>C	synonymous_variant	0.97	rifampicin
rpoC	765103	c.1734G>A	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765115	c.1746G>T	synonymous_variant	0.98	rifampicin
rpoC	765121	c.1752G>T	synonymous_variant	0.98	rifampicin
rpoC	765199	c.1830T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	765202	c.1833C>G	synonymous_variant	0.83	rifampicin
rpoC	765208	c.1839T>C	synonymous_variant	0.83	rifampicin
rpoC	765220	c.1851A>G	synonymous_variant	0.77	rifampicin
rpoC	765232	c.1863G>C	synonymous_variant	0.77	rifampicin
rpoC	765234	p.Ala622Val	missense_variant	0.77	rifampicin
rpoC	765277	c.1908G>T	synonymous_variant	0.91	rifampicin
rpoC	765281	p.Thr638Asp	missense_variant	0.91	rifampicin	Uncertain significance
rpoC	765300	p.Val644Ala	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	765305	c.1936_1938delATCinsGG	frameshift_variant&missense_variant	0.95	rifampicin
rpoC	765311	p.Ala648Thr	missense_variant	0.93	rifampicin	Uncertain significance
rpoC	765319	c.1950A>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	765326	c.1957_1959delCACinsGG	frameshift_variant&missense_variant	0.93	rifampicin
rpoC	765330	p.Ser654Asn	missense_variant	0.93	rifampicin	Uncertain significance
rpoC	765339	p.Gln657Arg	missense_variant	0.94	rifampicin	Uncertain significance
rpoC	765348	p.Asp660Gly	missense_variant	0.94	rifampicin
rpoC	765350	c.1981_1983delGCGinsTC	frameshift_variant&missense_variant	0.94	rifampicin
rpoC	765358	p.Met663Ile	missense_variant	0.96	rifampicin	Uncertain significance
rpoC	765370	c.2001G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765383	p.Met672Leu	missense_variant	0.99	rifampicin	Uncertain significance
rpoC	765404	p.Leu679Thr	missense_variant	0.99	rifampicin	Uncertain significance
rpoC	765409	c.2040T>C	synonymous_variant	0.99	rifampicin
rpoC	765412	c.2043T>C	synonymous_variant	0.99	rifampicin
rpoC	765421	c.2052C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765445	c.2076G>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765453	p.Ala695Val	missense_variant	0.99	rifampicin	Uncertain significance
rpoC	765478	c.2109T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765533	p.Tyr722His	missense_variant	0.98	rifampicin	Uncertain significance
rpoC	765547	c.2178C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765548	c.2179_2181delAGCinsTCG	synonymous_variant	0.98	rifampicin
rpoC	765553	c.2184C>A	synonymous_variant	0.97	rifampicin
rpoC	765556	c.2187G>C	synonymous_variant	0.97	rifampicin
rpoC	765562	c.2193G>C	synonymous_variant	0.97	rifampicin
rpoC	765565	c.2196G>C	synonymous_variant	0.97	rifampicin
rpoC	765611	p.His748Ser	missense_variant	0.97	rifampicin	Uncertain significance
rpoC	765625	c.2256C>T	synonymous_variant	0.97	rifampicin
rpoC	765628	c.2259G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765635	c.2266_2268delGTCinsCG	frameshift_variant&missense_variant	0.98	rifampicin
rpoC	765640	c.2271A>G	synonymous_variant	0.98	rifampicin
rpoC	765661	c.2292T>G	synonymous_variant	0.97	rifampicin
rpoC	765662	c.2293_2295delTTGinsCC	frameshift_variant&missense_variant	0.97	rifampicin
rpoC	765669	p.His767Arg	missense_variant	0.97	rifampicin
rpoC	765673	p.Asp768Glu	missense_variant	0.97	rifampicin
rpoC	765700	c.2331T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765718	p.Asp783Glu	missense_variant	0.98	rifampicin	Uncertain significance
rpoC	765721	c.2352G>A	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765724	c.2355C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765734	c.2365T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765739	c.2370G>T	synonymous_variant	0.98	rifampicin
rpoC	765742	p.Glu791Asp	missense_variant	0.98	rifampicin	Uncertain significance
rpoC	765751	c.2382C>G	synonymous_variant	0.99	rifampicin
rpoC	765753	p.Asp795Ala	missense_variant	0.99	rifampicin	Uncertain significance
rpoC	765772	c.2403C>G	synonymous_variant	0.99	rifampicin
rpoC	765787	c.2418C>T	synonymous_variant	0.99	rifampicin
rpoC	765790	c.2421C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765793	c.2424C>G	synonymous_variant	0.99	rifampicin
rpoC	765796	c.2427C>T	synonymous_variant	0.99	rifampicin
rpoC	765811	c.2442T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765814	c.2445A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765826	c.2457T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765835	c.2466C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765871	c.2502T>C	synonymous_variant	1.0	rifampicin
rpoC	765875	p.Val836Ile	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	765898	c.2529C>T	synonymous_variant	0.99	rifampicin
rpoC	765904	c.2535C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765908	c.2539C>T	synonymous_variant	0.99	rifampicin
rpoC	765937	c.2568T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765962	c.2593T>C	synonymous_variant	0.99	rifampicin
rpoC	765967	c.2598C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765973	c.2604C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765979	c.2610C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765982	c.2613C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765991	c.2622C>G	synonymous_variant	0.98	rifampicin
rpoC	765994	c.2625A>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766003	c.2634G>C	synonymous_variant	0.97	rifampicin
rpoC	766009	c.2640G>T	synonymous_variant	0.97	rifampicin
rpoC	766012	c.2643C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766043	p.Gln892Gly	missense_variant	0.93	rifampicin
rpoC	766061	p.Val898Ile	missense_variant	0.93	rifampicin
rpoC	766069	p.Glu900Asp	missense_variant	0.8	rifampicin
rpoC	766070	c.2701C>T	synonymous_variant	0.79	rifampicin	Not assoc w R
rpoC	766270	c.2901G>C	synonymous_variant	1.0	rifampicin
rpoC	766273	c.2904T>C	synonymous_variant	1.0	rifampicin
rpoC	766280	c.2911_2913delAGCinsGA	frameshift_variant&missense_variant	1.0	rifampicin
rpoC	766288	c.2919C>G	synonymous_variant	1.0	rifampicin
rpoC	766291	c.2922G>T	synonymous_variant	1.0	rifampicin
rpoC	766297	c.2928G>C	synonymous_variant	1.0	rifampicin
rpoC	766309	c.2940G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766312	c.2943T>A	synonymous_variant	1.0	rifampicin
rpoC	766315	c.2946C>G	synonymous_variant	1.0	rifampicin
rpoC	766348	c.2979A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766351	c.2982C>G	synonymous_variant	1.0	rifampicin
rpoC	766363	c.2994G>T	synonymous_variant	1.0	rifampicin
rpoC	766381	c.3012C>T	synonymous_variant	1.0	rifampicin
rpoC	766384	c.3015A>G	synonymous_variant	1.0	rifampicin
rpoC	766390	c.3021C>T	synonymous_variant	1.0	rifampicin
rpoC	766393	c.3024C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766408	c.3039C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766426	c.3057C>T	synonymous_variant	1.0	rifampicin
rpoC	766435	p.Glu1022Asp	missense_variant	0.99	rifampicin	Uncertain significance
rpoC	766456	c.3087C>G	synonymous_variant	0.99	rifampicin
rpoC	766459	c.3090G>T	synonymous_variant	0.99	rifampicin
rpoC	766484	c.3115_3117delGTAinsAT	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	766517	c.3148_3150delACCinsGT	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	766522	c.3153C>A	synonymous_variant	0.99	rifampicin
rpoC	766528	c.3159T>G	synonymous_variant	0.99	rifampicin
rpoC	766530	p.Arg1054Gln	missense_variant	0.99	rifampicin
rpoC	766537	c.3168G>A	synonymous_variant	0.99	rifampicin
rpoC	766540	p.Asp1057Glu	missense_variant	0.99	rifampicin
rpoC	766547	p.Arg1060Lys	missense_variant	0.99	rifampicin
rpoC	766564	c.3195C>G	synonymous_variant	0.99	rifampicin
rpoC	766570	c.3201T>G	synonymous_variant	0.99	rifampicin
rpoC	766573	c.3204T>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766576	c.3207C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766582	c.3213C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766585	c.3216T>C	synonymous_variant	0.99	rifampicin
rpoC	766607	c.3238_3240delATCinsCG	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	766610	p.Ser1081Pro	missense_variant	0.99	rifampicin
rpoC	766618	c.3249G>T	synonymous_variant	0.99	rifampicin
rpoC	766630	c.3261G>T	synonymous_variant	0.99	rifampicin
rpoC	766645	c.3276A>G	synonymous_variant	0.98	rifampicin
rpoC	766651	c.3282T>C	synonymous_variant	0.98	rifampicin
rpoC	766654	c.3285C>G	synonymous_variant	0.98	rifampicin
rpoC	766657	c.3288A>G	synonymous_variant	0.98	rifampicin
rpoC	766661	p.Val1098Leu	missense_variant	0.98	rifampicin
rpoC	766666	c.3297C>G	synonymous_variant	0.98	rifampicin
rpoC	766672	c.3303T>C	synonymous_variant	0.98	rifampicin
rpoC	766690	c.3321G>T	synonymous_variant	0.98	rifampicin
rpoC	766702	c.3333G>C	synonymous_variant	0.98	rifampicin
rpoC	766708	c.3339A>G	synonymous_variant	0.98	rifampicin
rpoC	766711	c.3342C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766726	c.3357T>C	synonymous_variant	0.99	rifampicin
rpoC	766738	c.3369G>T	synonymous_variant	0.98	rifampicin
rpoC	766750	c.3381C>G	synonymous_variant	0.98	rifampicin
rpoC	766753	c.3384C>T	synonymous_variant	0.98	rifampicin
rpoC	766765	c.3396A>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766771	c.3402G>C	synonymous_variant	0.98	rifampicin
rpoC	766774	c.3405T>C	synonymous_variant	0.98	rifampicin
rpoC	766775	p.Arg1136Asn	missense_variant	0.98	rifampicin
rpoC	766787	p.Glu1140Gln	missense_variant	0.98	rifampicin	Uncertain significance
rpoC	766804	c.3435A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766843	c.3474T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766846	c.3477C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766883	c.3514_3516delTCGinsGC	frameshift_variant&missense_variant	0.98	rifampicin
rpoC	766894	c.3525T>C	synonymous_variant	0.99	rifampicin
rpoC	766895	c.3526T>C	synonymous_variant	0.99	rifampicin
rpoC	766900	c.3531T>C	synonymous_variant	0.99	rifampicin
rpoC	766903	c.3534C>T	synonymous_variant	0.99	rifampicin
rpoC	766911	p.Ile1181Thr	missense_variant	0.99	rifampicin
rpoC	766915	p.Asp1182Glu	missense_variant	0.99	rifampicin
rpoC	766921	c.3552G>C	synonymous_variant	0.99	rifampicin
rpoC	766931	c.3562_3564delGCAinsAC	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	766935	p.Glu1189Ala	missense_variant	0.99	rifampicin
rpoC	766942	c.3573C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766945	c.3576A>T	synonymous_variant	0.99	rifampicin
rpoC	766961	p.Gly1198Leu	missense_variant	0.99	rifampicin
rpoC	766978	c.3609C>A	synonymous_variant	0.99	rifampicin
rpoC	766996	c.3627C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767002	c.3633G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767041	c.3672G>T	synonymous_variant	0.99	rifampicin
rpoC	767044	c.3675G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767059	c.3690T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767068	c.3699G>T	synonymous_variant	0.99	rifampicin
rpoC	767098	c.3729T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767104	c.3735C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767105	c.3736_3738delAACinsCG	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	767110	c.3741T>C	synonymous_variant	0.99	rifampicin
rpoC	767119	c.3750A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767128	c.3759C>T	synonymous_variant	1.0	rifampicin
rpoC	767152	c.3783T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767158	c.3789T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767167	c.3798C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	767182	c.3813G>C	synonymous_variant	0.99	rifampicin
rpoC	767197	c.3828G>A	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	767206	c.3837C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	767209	c.3840T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	767212	c.3843G>T	synonymous_variant	0.95	rifampicin
rpoC	767221	c.3852C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	767230	c.3861G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	767233	c.3864T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	767263	c.3894T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	767266	c.3897G>C	synonymous_variant	0.95	rifampicin
rpoC	767278	c.3909T>C	synonymous_variant	0.94	rifampicin
rpoC	767281	c.3912C>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	767284	c.3915C>T	synonymous_variant	0.93	rifampicin
rpoC	767302	c.3933C>G	synonymous_variant	0.92	rifampicin
mmpL5	775829	c.2652C>G	synonymous_variant	0.42	clofazimine
mmpL5	775829	c.2652C>G	synonymous_variant	0.42	bedaquiline
mmpL5	775832	c.2647_2649delGCCinsTG	frameshift_variant&missense_variant	0.56	clofazimine	Uncertain significance
mmpL5	775832	c.2647_2649delGCCinsTG	frameshift_variant&missense_variant	0.56	bedaquiline	Uncertain significance
mmpL5	775835	c.2646C>G	synonymous_variant	0.47	clofazimine
mmpL5	775835	c.2646C>G	synonymous_variant	0.47	bedaquiline
mmpL5	775838	c.2643G>C	synonymous_variant	0.38	clofazimine
mmpL5	775838	c.2643G>C	synonymous_variant	0.38	bedaquiline
mmpL5	775845	p.Ser879Lys	missense_variant	0.6	clofazimine
mmpL5	775845	p.Ser879Lys	missense_variant	0.6	bedaquiline
mmpL5	775851	p.Ser877Thr	missense_variant	0.67	clofazimine
mmpL5	775851	p.Ser877Thr	missense_variant	0.67	bedaquiline
mmpL5	775856	c.2625T>C	synonymous_variant	1.0	clofazimine
mmpL5	775856	c.2625T>C	synonymous_variant	1.0	bedaquiline
mmpL5	775865	c.2616T>C	synonymous_variant	1.0	clofazimine
mmpL5	775865	c.2616T>C	synonymous_variant	1.0	bedaquiline
mmpL5	775880	c.2599_2601delAACinsCT	frameshift_variant&missense_variant	0.92	clofazimine	Uncertain significance
mmpL5	775880	c.2599_2601delAACinsCT	frameshift_variant&missense_variant	0.92	bedaquiline	Uncertain significance
mmpL5	775883	c.2596_2598delATCinsCA	frameshift_variant&missense_variant	0.78	clofazimine	Uncertain significance
mmpL5	775883	c.2596_2598delATCinsCA	frameshift_variant&missense_variant	0.78	bedaquiline	Uncertain significance
mmpL5	775886	c.2595A>C	synonymous_variant	0.87	clofazimine
mmpL5	775886	c.2595A>C	synonymous_variant	0.87	bedaquiline
mmpL5	775904	c.2577G>A	synonymous_variant	0.71	clofazimine
mmpL5	775904	c.2577G>A	synonymous_variant	0.71	bedaquiline
mmpL5	775909	p.Leu858Phe	missense_variant	0.76	clofazimine
mmpL5	775909	p.Leu858Phe	missense_variant	0.76	bedaquiline
mmpL5	775915	p.Ala856Ser	missense_variant	0.45	clofazimine
mmpL5	775915	p.Ala856Ser	missense_variant	0.45	bedaquiline
mmpL5	775916	c.2565T>G	synonymous_variant	0.75	clofazimine
mmpL5	775916	c.2565T>G	synonymous_variant	0.75	bedaquiline
mmpL5	775921	c.2560C>T	synonymous_variant	0.58	clofazimine
mmpL5	775921	c.2560C>T	synonymous_variant	0.58	bedaquiline
mmpL5	775922	c.2559G>A	synonymous_variant	0.68	clofazimine
mmpL5	775922	c.2559G>A	synonymous_variant	0.68	bedaquiline
mmpL5	775937	c.2542_2544delGCGinsTC	frameshift_variant&missense_variant	0.71	clofazimine	Uncertain significance
mmpL5	775937	c.2542_2544delGCGinsTC	frameshift_variant&missense_variant	0.71	bedaquiline	Uncertain significance
mmpL5	775940	c.2541C>T	synonymous_variant	0.32	clofazimine
mmpL5	775940	c.2541C>T	synonymous_variant	0.32	bedaquiline
mmpL5	775943	c.2538C>G	synonymous_variant	0.75	clofazimine
mmpL5	775943	c.2538C>G	synonymous_variant	0.75	bedaquiline
mmpL5	775946	c.2535C>G	synonymous_variant	0.82	clofazimine
mmpL5	775946	c.2535C>G	synonymous_variant	0.82	bedaquiline
mmpL5	775966	p.Ala839Ser	missense_variant	0.77	clofazimine
mmpL5	775966	p.Ala839Ser	missense_variant	0.77	bedaquiline
mmpL5	775971	p.Ala837Val	missense_variant	0.56	clofazimine
mmpL5	775971	p.Ala837Val	missense_variant	0.56	bedaquiline
mmpL5	775975	c.2506T>C	synonymous_variant	0.92	clofazimine
mmpL5	775975	c.2506T>C	synonymous_variant	0.92	bedaquiline
mmpL5	775992	p.Glu830Pro	missense_variant	0.43	clofazimine
mmpL5	775992	p.Glu830Pro	missense_variant	0.43	bedaquiline
mmpL5	775994	c.2487C>T	synonymous_variant	0.75	clofazimine
mmpL5	775994	c.2487C>T	synonymous_variant	0.75	bedaquiline
mmpL5	775997	c.2484T>C	synonymous_variant	0.85	clofazimine
mmpL5	775997	c.2484T>C	synonymous_variant	0.85	bedaquiline
mmpL5	776036	c.2445G>A	synonymous_variant	0.32	clofazimine
mmpL5	776036	c.2445G>A	synonymous_variant	0.32	bedaquiline
rpsL	781571	c.12C>T	synonymous_variant	0.91	streptomycin
rpsL	781586	c.27C>T	synonymous_variant	0.97	streptomycin
rpsL	781592	c.33T>C	synonymous_variant	0.97	streptomycin
rpsL	781595	c.36T>C	synonymous_variant	0.97	streptomycin
rpsL	781598	c.39G>C	synonymous_variant	0.97	streptomycin
rpsL	781605	p.Ile16Val	missense_variant	0.97	streptomycin	Uncertain significance
rpsL	781608	p.Ser17Ala	missense_variant	0.97	streptomycin
rpsL	781616	c.57C>G	synonymous_variant	0.95	streptomycin
rpsL	781628	c.69T>C	synonymous_variant	0.95	streptomycin	Not assoc w R - Interim
rpsL	781631	c.72G>C	synonymous_variant	0.95	streptomycin
rpsL	781649	c.90T>A	synonymous_variant	0.97	streptomycin
rpsL	781652	c.93T>G	synonymous_variant	0.97	streptomycin
rpsL	781655	c.96T>C	synonymous_variant	0.97	streptomycin
rpsL	781658	c.99A>G	synonymous_variant	0.97	streptomycin
rpsL	781682	c.123T>C	synonymous_variant	0.98	streptomycin
rpsL	781709	c.150G>C	synonymous_variant	0.98	streptomycin	Not assoc w R - Interim
rpsL	781715	c.156T>G	synonymous_variant	0.97	streptomycin
rpsL	781718	c.159C>G	synonymous_variant	0.98	streptomycin
rpsL	781724	c.165G>C	synonymous_variant	0.98	streptomycin
rpsL	781728	c.169T>C	synonymous_variant	0.98	streptomycin
rpsL	781733	c.174G>C	synonymous_variant	0.98	streptomycin
rpsL	781736	c.177T>C	synonymous_variant	0.98	streptomycin
rpsL	781742	c.183C>G	synonymous_variant	0.98	streptomycin
rpsL	781748	c.189C>G	synonymous_variant	0.98	streptomycin
rpsL	781751	c.192G>C	synonymous_variant	0.98	streptomycin
rpsL	781754	c.195G>C	synonymous_variant	0.98	streptomycin
rpsL	781760	c.201T>C	synonymous_variant	0.98	streptomycin
rpsL	781763	c.204C>G	synonymous_variant	0.98	streptomycin
rpsL	781766	c.207C>T	synonymous_variant	0.99	streptomycin	Not assoc w R - Interim
rpsL	781772	c.213C>T	synonymous_variant	0.99	streptomycin	Not assoc w R - Interim
rpsL	781805	c.246G>T	synonymous_variant	0.99	streptomycin
rpsL	781808	c.249C>T	synonymous_variant	0.99	streptomycin
rpsL	781811	c.252C>T	synonymous_variant	0.99	streptomycin
rpsL	781814	c.255C>T	synonymous_variant	0.99	streptomycin
rpsL	781817	c.258G>T	synonymous_variant	0.99	streptomycin
rpsL	781832	c.273T>G	synonymous_variant	0.99	streptomycin
rpsL	781859	c.300T>C	synonymous_variant	0.98	streptomycin	Not assoc w R - Interim
rpsL	781868	c.309T>C	synonymous_variant	0.98	streptomycin
rpsL	781871	c.312G>C	synonymous_variant	0.98	streptomycin
rpsL	781877	c.318T>A	synonymous_variant	0.99	streptomycin
rpsL	781892	c.333A>G	synonymous_variant	0.98	streptomycin
rpsL	781898	c.339A>C	synonymous_variant	0.98	streptomycin
rpsL	781907	c.348T>C	synonymous_variant	0.98	streptomycin
rpsL	781916	c.357T>G	synonymous_variant	0.98	streptomycin
rpsL	781929	p.Gly124Ser	missense_variant	0.97	streptomycin	Uncertain significance
rplC	800609	c.-200G>A	upstream_gene_variant	0.77	linezolid
rplC	800612	c.-197A>G	upstream_gene_variant	0.82	linezolid
rplC	800618	c.-191T>C	upstream_gene_variant	0.84	linezolid
rplC	800621	c.-188G>A	upstream_gene_variant	0.89	linezolid
rplC	800639	c.-170C>T	upstream_gene_variant	0.93	linezolid
rplC	800645	c.-164C>G	upstream_gene_variant	0.94	linezolid
rplC	800648	c.-161A>C	upstream_gene_variant	0.94	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	0.94	linezolid
rplC	800693	c.-116A>C	upstream_gene_variant	0.92	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	0.92	linezolid
rplC	800715	c.-94A>C	upstream_gene_variant	0.92	linezolid
rplC	800744	c.-65G>T	upstream_gene_variant	0.92	linezolid
rplC	800745	c.-64_-62delCTCinsTG	upstream_gene_variant	0.94	linezolid
rplC	800759	c.-50C>T	upstream_gene_variant	0.93	linezolid
rplC	800762	c.-47T>G	upstream_gene_variant	0.93	linezolid
rplC	800783	c.-26C>T	upstream_gene_variant	0.87	linezolid
rplC	800789	c.-20G>A	upstream_gene_variant	0.75	linezolid
fbiC	1303425	c.495G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303435	c.505_506delTCinsAG	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303441	c.511T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303444	p.Ser172Ala	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303452	c.522G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303455	c.525C>G	synonymous_variant	1.0	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1303464	c.534A>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303469	p.Arg180Leu	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303488	c.558G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303492	c.562T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303509	c.579G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303512	c.582T>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303545	c.615A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303575	c.645G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303581	c.651G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303587	c.657G>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303590	c.660A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303602	c.672A>G	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fbiC	1303608	c.678G>A	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1303611	c.681G>A	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1303614	c.684C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1303617	c.687C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1303632	c.702T>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1303638	c.708A>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1303646	p.Ala239Val	missense_variant	0.93	clofazimine
					pretomanid
					delamanid
fbiC	1303653	c.723G>C	synonymous_variant	0.87	clofazimine
					pretomanid
					delamanid
fbiC	1303947	c.1017T>G	synonymous_variant	0.88	clofazimine
					pretomanid
					delamanid
fbiC	1303949	p.Gly340Ala	missense_variant	0.89	clofazimine
					pretomanid
					delamanid
fbiC	1303953	p.Asp341Glu	missense_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1303961	p.Arg344Leu	missense_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1303998	c.1068T>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304001	c.1071C>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304004	c.1074A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304008	c.1078T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304013	c.1083G>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304022	c.1092T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304028	c.1098C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304034	c.1104A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304046	c.1116C>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304049	c.1119T>A	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304050	c.1120T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304058	p.Glu376Asp	missense_variant	0.98	clofazimine
					pretomanid
					delamanid	Uncertain significance
fbiC	1304064	c.1134G>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304068	p.Val380Ile	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304075	p.Ala382Glu	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304077	p.Glu383Gln	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304092	p.Met388Leu	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304106	c.1176G>T	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304112	c.1182G>T	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304465	p.Gly512Ala	missense_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304478	c.1548G>A	synonymous_variant	0.93	clofazimine
					pretomanid
					delamanid
fbiC	1304490	c.1560C>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304496	c.1566T>A	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304499	c.1569T>G	synonymous_variant	0.94	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid
fbiC	1304502	c.1572G>T	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304503	p.Leu525Met	missense_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiC	1304508	p.Glu526Asp	missense_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304526	c.1596T>C	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304529	c.1599T>C	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304533	c.1603T>C	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304538	c.1608C>T	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304546	p.Val539Ala	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304559	p.Glu543Asp	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304567	p.Phe546Tyr	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304580	c.1650T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304608	p.Thr560Val	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304613	c.1683T>C	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304625	c.1695C>T	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304640	c.1710A>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304646	c.1716T>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1305126	c.2196T>C	synonymous_variant	1.0	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1305135	c.2205C>T	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1305147	c.2217C>T	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1305150	c.2220C>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305168	c.2238C>T	synonymous_variant	0.98	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1305173	p.Asn748Ser	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1305177	c.2247A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1305181	c.2251T>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1305195	c.2265T>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1305197	p.Ala756Gly	missense_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1305204	c.2274C>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305210	c.2280G>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1305213	c.2283C>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305216	c.2286C>T	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305237	c.2307A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305240	c.2310T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305243	c.2313T>G	synonymous_variant	0.98	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid
fbiC	1305270	c.2340C>T	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1305277	p.His783Asn	missense_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1305282	c.2352T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305297	c.2367G>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305300	c.2370A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305310	p.Arg794Glu	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305339	c.2409C>A	synonymous_variant	0.99	clofazimine
					pretomanid
					delamanid
fbiC	1305393	c.2463T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305399	c.2469A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1305417	c.2487C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1305418	p.Val830Ile	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1305423	c.2493T>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1305443	p.Glu838Ala	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1305456	c.2526C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1305462	c.2532G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
sigE	1364772	c.360G>A	synonymous_variant	0.94	pyrazinamide
sigE	1364784	c.372C>G	synonymous_variant	0.96	pyrazinamide
sigE	1364787	p.Gln125His	missense_variant	0.96	pyrazinamide
sigE	1364790	c.378T>C	synonymous_variant	0.96	pyrazinamide
sigE	1364799	c.387G>C	synonymous_variant	1.0	pyrazinamide
sigE	1364802	c.390C>A	synonymous_variant	1.0	pyrazinamide
sigE	1364814	c.402C>T	synonymous_variant	1.0	pyrazinamide
sigE	1364818	c.406_408delCTAinsTG	frameshift_variant&stop_gained	1.0	pyrazinamide	Uncertain significance
sigE	1364835	c.423C>G	synonymous_variant	1.0	pyrazinamide
sigE	1364839	c.427T>C	synonymous_variant	1.0	pyrazinamide
sigE	1364856	c.444C>G	synonymous_variant	1.0	pyrazinamide
sigE	1364860	c.448_450delCGCinsAG	frameshift_variant&missense_variant	1.0	pyrazinamide	Uncertain significance
sigE	1364865	c.453G>C	synonymous_variant	1.0	pyrazinamide
sigE	1364867	p.Ala152Gly	missense_variant	1.0	pyrazinamide
sigE	1364871	c.459C>G	synonymous_variant	1.0	pyrazinamide
sigE	1364872	p.Ile154Val	missense_variant	1.0	pyrazinamide
sigE	1364877	c.465G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
sigE	1364887	c.475_477delTTAinsCG	frameshift_variant&missense_variant	0.99	pyrazinamide	Uncertain significance
sigE	1364892	c.480C>G	synonymous_variant	0.99	pyrazinamide
sigE	1364919	c.507T>C	synonymous_variant	0.99	pyrazinamide
sigE	1364925	c.513C>G	synonymous_variant	0.99	pyrazinamide
sigE	1364926	p.Asn172Asp	missense_variant	0.99	pyrazinamide
sigE	1364960	p.Gly183Asp	missense_variant	0.98	pyrazinamide
sigE	1364964	c.552T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
sigE	1364976	c.564T>G	synonymous_variant	0.97	pyrazinamide
sigE	1364979	c.567C>G	synonymous_variant	0.97	pyrazinamide
sigE	1364984	p.Ala191Asp	missense_variant	0.97	pyrazinamide
sigE	1364992	p.Pro194Ala	missense_variant	0.97	pyrazinamide
sigE	1365003	c.591T>C	synonymous_variant	0.97	pyrazinamide
sigE	1365006	c.594T>G	synonymous_variant	0.97	pyrazinamide
sigE	1365015	c.603G>C	synonymous_variant	0.97	pyrazinamide
sigE	1365024	c.612T>C	synonymous_variant	0.97	pyrazinamide
sigE	1365033	c.621G>A	synonymous_variant	0.96	pyrazinamide
sigE	1365042	c.630G>C	synonymous_variant	0.98	pyrazinamide
sigE	1365048	c.636G>A	synonymous_variant	0.97	pyrazinamide
sigE	1365052	p.Ile214Val	missense_variant	0.97	pyrazinamide	Uncertain significance
sigE	1365057	c.645C>T	synonymous_variant	0.95	pyrazinamide
sigE	1365063	c.651A>C	synonymous_variant	0.95	pyrazinamide
sigE	1365066	c.654G>T	synonymous_variant	0.93	pyrazinamide
sigE	1365069	c.657C>T	synonymous_variant	0.93	pyrazinamide
atpE	1461086	c.42A>T	synonymous_variant	0.9	bedaquiline
atpE	1461089	c.45G>C	synonymous_variant	0.92	bedaquiline
atpE	1461097	p.Ala18Gly	missense_variant	0.95	bedaquiline
atpE	1461101	c.57T>C	synonymous_variant	0.96	bedaquiline
atpE	1461104	c.60C>T	synonymous_variant	0.96	bedaquiline
atpE	1461132	p.Val30Ile	missense_variant	1.0	bedaquiline
atpE	1461149	c.105T>G	synonymous_variant	1.0	bedaquiline
atpE	1461153	p.Ser37Ala	missense_variant	1.0	bedaquiline	Uncertain significance
atpE	1461159	p.Val39Ile	missense_variant	1.0	bedaquiline	Uncertain significance
atpE	1461167	c.123G>T	synonymous_variant	1.0	bedaquiline
atpE	1461170	c.126A>G	synonymous_variant	1.0	bedaquiline
atpE	1461176	c.132G>A	synonymous_variant	1.0	bedaquiline
atpE	1461179	c.135G>T	synonymous_variant	0.97	bedaquiline
atpE	1461182	c.138A>G	synonymous_variant	1.0	bedaquiline
atpE	1461185	c.141G>T	synonymous_variant	1.0	bedaquiline
atpE	1461188	c.144G>C	synonymous_variant	1.0	bedaquiline
atpE	1461197	c.153A>C	synonymous_variant	1.0	bedaquiline
atpE	1461212	c.168C>G	synonymous_variant	1.0	bedaquiline
atpE	1461215	c.171C>T	synonymous_variant	0.97	bedaquiline
atpE	1461219	c.175T>C	synonymous_variant	0.97	bedaquiline
atpE	1461224	c.180T>C	synonymous_variant	0.97	bedaquiline
atpE	1461227	c.183G>A	synonymous_variant	0.97	bedaquiline
atpE	1461233	c.189A>C	synonymous_variant	0.97	bedaquiline
atpE	1461251	c.207G>C	synonymous_variant	0.86	bedaquiline
atpE	1461254	c.210T>C	synonymous_variant	0.82	bedaquiline
rrs	1471845	n.-1G>T	upstream_gene_variant	0.87	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471923	n.78T>C	non_coding_transcript_exon_variant	0.97	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471925	n.80T>C	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471932	n.87A>G	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471934	n.89A>G	non_coding_transcript_exon_variant	0.98	streptomycin	Uncertain significance
					kanamycin
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471986	n.141C>T	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472019	n.174G>A	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472031	n.186G>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472033	n.188A>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472035	n.190G>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472040	n.195T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472041	n.196C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472042	n.197T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472053	n.211_212delGC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472061	n.216A>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472106	n.261G>A	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472286	n.441C>G	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472287	n.442C>T	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472292	n.447A>G	non_coding_transcript_exon_variant	0.98	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472298	n.453G>C	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472302	n.457_462delGGGTTCinsAGGATTCT	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472311	n.466C>T	non_coding_transcript_exon_variant	0.98	streptomycin	Uncertain significance
					kanamycin
					capreomycin
					amikacin
rrs	1472314	n.469A>G	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472315	n.470T>G	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472327	n.482G>A	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472328	n.483G>C	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin
					capreomycin
					amikacin
rrs	1472431	n.586G>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472438	n.593T>C	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472446	n.601T>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472452	n.607G>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472464	n.619A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472489	n.644A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472498	n.653C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472683	n.838_839insTA	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472847	n.1002G>C	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472848	n.1003T>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472849	n.1004C>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472858	n.1013G>T	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472859	n.1014G>C	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472860	n.1015C>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472973	n.1128A>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473100	n.1255G>C	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473109	n.1264T>G	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473111	n.1266A>T	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473123	n.1278A>T	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473276	n.1431A>G	non_coding_transcript_exon_variant	0.98	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473290	n.1445C>T	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473291	n.1446_1447insT	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473301	n.1456T>C	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1473717	n.60G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473717	n.60G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473746	n.89T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473746	n.89T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473811	n.154C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473811	n.154C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473812	n.155G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473812	n.155G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473814	n.157A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473814	n.157A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473815	n.158T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473815	n.158T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473816	n.159C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473816	n.159C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473822	n.165A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473822	n.165A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473839	n.182G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473839	n.182G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1473887	n.230delTinsAA	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473887	n.230delTinsAA	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1473899	n.242A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473899	n.242A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1473916	n.259C>A	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473916	n.259C>A	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1473922	n.265A>G	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1473922	n.265A>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473923	n.266C>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473923	n.266C>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1473924	n.267_268insT	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1473924	n.267_268insT	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473935	n.278C>T	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1473935	n.278C>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473937	n.280C>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473937	n.280C>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473945	n.288T>A	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473945	n.288T>A	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473946	n.289A>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473946	n.289A>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473982	n.325_326delGAinsTGT	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1473982	n.325_326delGAinsTGT	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1473984	n.327T>C	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1473984	n.327T>C	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1473991	n.334_335delCAinsG	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1473991	n.334_335delCAinsG	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1473994	n.337C>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1473994	n.337C>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Not assoc w R
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	0.96	linezolid	Not assoc w R
rrl	1474005	n.348T>C	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1474005	n.348T>C	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1474006	n.350delA	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1474006	n.350delA	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1474011	n.354_355insA	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474011	n.354_355insA	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474016	n.359C>G	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1474016	n.359C>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474026	n.369C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474026	n.369C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474045	n.388C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474045	n.388C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474054	n.397T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474054	n.397T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474083	n.426C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474083	n.426C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474094	n.437C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474094	n.437C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474100	n.443C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474100	n.443C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474105	n.448_449insG	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474105	n.448_449insG	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474108	n.451C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474108	n.451C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474110	n.453A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474110	n.453A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474181	n.524C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474181	n.524C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474263	n.606G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474263	n.606G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474284	n.629dupC	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1474284	n.629dupC	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474290	n.633T>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474290	n.633T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474292	n.636_644delTCCTCTCCG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474292	n.636_644delTCCTCTCCG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474303	n.646A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474303	n.646A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474306	n.649A>T	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1474306	n.649A>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474308	n.653_654delTG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474308	n.653_654delTG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474350	n.693G>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474350	n.693G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474351	n.694G>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474351	n.694G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474353	n.696A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474353	n.696A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474413	n.756A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474413	n.756A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474414	n.757C>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474414	n.757C>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474415	n.758C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474415	n.758C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474420	n.763C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474420	n.763C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474421	n.764G>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474421	n.764G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474423	n.767_768delCA	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474423	n.767_768delCA	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474427	n.770A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474427	n.770A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474428	n.771C>G	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474428	n.771C>G	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474430	n.773C>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474430	n.773C>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474432	n.775C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474432	n.775C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474437	n.781_782delAA	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474437	n.781_782delAA	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474452	n.795C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474452	n.795C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474552	n.895C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474552	n.895C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474638	n.981C>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474638	n.981C>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474639	n.982G>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474639	n.982G>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474708	n.1052dupG	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474708	n.1052dupG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474711	n.1054_1055insA	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474711	n.1054_1055insA	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474715	n.1061delA	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474715	n.1061delA	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474794	n.1137C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474794	n.1137C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474830	n.1173A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474830	n.1173A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474831	n.1174A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474831	n.1174A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475062	n.1405A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475062	n.1405A>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475120	n.1463G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475120	n.1463G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475202	n.1545G>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475202	n.1545G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475209	n.1552G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475209	n.1552G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475221	n.1564C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475221	n.1564C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475240	n.1583C>G	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1475240	n.1583C>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1475241	n.1584C>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475241	n.1584C>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475242	n.1585G>T	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475242	n.1585G>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475244	n.1587A>G	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475244	n.1587A>G	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475252	n.1595C>A	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475252	n.1595C>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475253	n.1600delC	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475253	n.1600delC	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475265	n.1608_1609delGTinsAGC	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475265	n.1608_1609delGTinsAGC	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475268	n.1611T>A	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475268	n.1611T>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475269	n.1612G>C	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475269	n.1612G>C	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475272	n.1615G>C	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475272	n.1615G>C	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475274	n.1617T>G	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475274	n.1617T>G	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475276	n.1622_1623delGG	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475276	n.1622_1623delGG	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475375	n.1718G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475375	n.1718G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475376	n.1719A>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475376	n.1719A>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475378	n.1721A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475378	n.1721A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475379	n.1722G>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475379	n.1722G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475396	n.1739_1740insTG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475396	n.1739_1740insTG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475399	n.1742T>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475399	n.1742T>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475400	n.1743C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475400	n.1743C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475401	n.1745delC	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475401	n.1745delC	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475406	n.1749T>G	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475406	n.1749T>G	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475407	n.1750C>T	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1475407	n.1750C>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1475409	n.1752T>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475409	n.1752T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475433	n.1776A>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475433	n.1776A>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475460	n.1803A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475460	n.1803A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475480	n.1823A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475480	n.1823A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475573	n.1916G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475573	n.1916G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475603	n.1946G>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475603	n.1946G>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475612	n.1955G>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475612	n.1955G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475614	n.1957A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475614	n.1957A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475615	n.1958C>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475615	n.1958C>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475619	n.1962C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475619	n.1962C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475621	n.1964T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475621	n.1964T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475626	n.1969delTinsCC	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475626	n.1969delTinsCC	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475629	n.1972G>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475629	n.1972G>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475753	n.2096C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475753	n.2096C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475762	n.2105G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475762	n.2105G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475763	n.2106C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475763	n.2106C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475764	n.2107A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475764	n.2107A>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475765	n.2108A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475765	n.2108A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475775	n.2118G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475775	n.2118G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475997	n.2340A>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475997	n.2340A>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476086	n.2429G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476086	n.2429G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476095	n.2438C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476095	n.2438C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476103	n.2446C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476103	n.2446C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476108	n.2451T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476108	n.2451T>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476110	n.2453G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476110	n.2453G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476246	n.2589G>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476246	n.2589G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476256	n.2599A>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476256	n.2599A>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476262	n.2605G>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476262	n.2605G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476529	n.2872A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476529	n.2872A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476616	n.2959A>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476616	n.2959A>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476665	n.3008T>A	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476665	n.3008T>A	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476679	n.3022T>A	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476679	n.3022T>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1476717	n.3060C>T	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1476717	n.3060C>T	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476725	n.3068C>T	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1476725	n.3068C>T	non_coding_transcript_exon_variant	0.88	linezolid	Uncertain significance
rrl	1476726	n.3069A>G	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476726	n.3069A>G	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476746	n.3089T>A	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476746	n.3089T>A	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476748	n.3091A>C	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476748	n.3091A>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476753	n.3096T>G	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476753	n.3096T>G	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476755	n.3098G>T	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476755	n.3098G>T	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	0.91	linezolid
fabG1	1673633	p.Ser65Asn	missense_variant	0.8	ethionamide
fabG1	1673633	p.Ser65Asn	missense_variant	0.8	isoniazid
inhA	1673646	c.-556T>C	upstream_gene_variant	0.95	ethionamide
inhA	1673646	c.-556T>C	upstream_gene_variant	0.95	isoniazid
fabG1	1673657	p.Thr73Lys	missense_variant	0.92	ethionamide
fabG1	1673657	p.Thr73Lys	missense_variant	0.92	isoniazid
fabG1	1673660	p.Ala74Glu	missense_variant	0.92	ethionamide
fabG1	1673660	p.Ala74Glu	missense_variant	0.92	isoniazid
inhA	1673664	c.-538A>C	upstream_gene_variant	0.92	ethionamide
inhA	1673664	c.-538A>C	upstream_gene_variant	0.92	isoniazid
inhA	1673667	c.-535A>G	upstream_gene_variant	0.92	ethionamide
inhA	1673667	c.-535A>G	upstream_gene_variant	0.92	isoniazid
inhA	1673682	c.-520G>C	upstream_gene_variant	0.97	ethionamide	Uncertain significance
inhA	1673682	c.-520G>C	upstream_gene_variant	0.97	isoniazid	Uncertain significance
inhA	1673691	c.-511G>A	upstream_gene_variant	0.97	ethionamide
inhA	1673691	c.-511G>A	upstream_gene_variant	0.97	isoniazid	Uncertain significance
fabG1	1673698	p.Ser87Ala	missense_variant	0.95	ethionamide
fabG1	1673698	p.Ser87Ala	missense_variant	0.95	isoniazid
fabG1	1673710	c.271_273delCTAinsAC	frameshift_variant&missense_variant	0.93	ethionamide
fabG1	1673710	c.271_273delCTAinsAC	frameshift_variant&missense_variant	0.93	isoniazid
fabG1	1673716	p.Ala93Lys	missense_variant	0.93	ethionamide
fabG1	1673716	p.Ala93Lys	missense_variant	0.93	isoniazid
inhA	1673724	c.-478A>G	upstream_gene_variant	0.93	ethionamide
inhA	1673724	c.-478A>G	upstream_gene_variant	0.93	isoniazid
inhA	1673730	c.-472C>G	upstream_gene_variant	0.93	ethionamide
inhA	1673730	c.-472C>G	upstream_gene_variant	0.93	isoniazid
inhA	1673748	c.-454A>G	upstream_gene_variant	0.95	ethionamide
inhA	1673748	c.-454A>G	upstream_gene_variant	0.95	isoniazid
fabG1	1673749	p.Lys104Arg	missense_variant	0.95	ethionamide
fabG1	1673749	p.Lys104Arg	missense_variant	0.95	isoniazid
inhA	1673757	c.-445G>A	upstream_gene_variant	0.93	ethionamide
inhA	1673757	c.-445G>A	upstream_gene_variant	0.93	isoniazid
fabG1	1673758	p.Lys107Glu	missense_variant	0.93	ethionamide
fabG1	1673758	p.Lys107Glu	missense_variant	0.93	isoniazid
inhA	1673784	c.-418G>A	upstream_gene_variant	0.9	ethionamide
inhA	1673784	c.-418G>A	upstream_gene_variant	0.9	isoniazid
inhA	1673787	c.-415G>T	upstream_gene_variant	0.89	ethionamide
inhA	1673787	c.-415G>T	upstream_gene_variant	0.89	isoniazid	Uncertain significance
inhA	1673796	c.-406G>C	upstream_gene_variant	0.86	ethionamide
inhA	1673796	c.-406G>C	upstream_gene_variant	0.86	isoniazid
fabG1	1673797	c.358_360delGCTinsAG	frameshift_variant&missense_variant	0.86	ethionamide
fabG1	1673797	c.358_360delGCTinsAG	frameshift_variant&missense_variant	0.86	isoniazid
inhA	1673802	c.-400A>G	upstream_gene_variant	0.86	ethionamide
inhA	1673802	c.-400A>G	upstream_gene_variant	0.86	isoniazid
inhA	1673808	c.-394A>C	upstream_gene_variant	0.9	ethionamide
inhA	1673808	c.-394A>C	upstream_gene_variant	0.9	isoniazid
inhA	1674387	c.186A>G	synonymous_variant	0.91	ethionamide
inhA	1674387	c.186A>G	synonymous_variant	0.91	isoniazid
inhA	1674399	c.198A>G	synonymous_variant	0.92	ethionamide
inhA	1674399	c.198A>G	synonymous_variant	0.92	isoniazid
inhA	1674416	p.Ala72Gly	missense_variant	0.92	ethionamide
inhA	1674416	p.Ala72Gly	missense_variant	0.92	isoniazid
inhA	1674418	c.217_219delAGCinsTCG	synonymous_variant	0.92	ethionamide
inhA	1674418	c.217_219delAGCinsTCG	synonymous_variant	0.92	isoniazid
inhA	1674426	c.225C>T	synonymous_variant	0.89	ethionamide
inhA	1674426	c.225C>T	synonymous_variant	0.89	isoniazid
inhA	1674428	p.Gly76Glu	missense_variant	0.89	ethionamide
inhA	1674428	p.Gly76Glu	missense_variant	0.89	isoniazid
inhA	1674432	c.231G>C	synonymous_variant	0.92	ethionamide
inhA	1674432	c.231G>C	synonymous_variant	0.92	isoniazid
inhA	1674435	c.234G>C	synonymous_variant	0.92	ethionamide
inhA	1674435	c.234G>C	synonymous_variant	0.92	isoniazid
inhA	1674443	p.Ala81Val	missense_variant	0.93	ethionamide
inhA	1674443	p.Ala81Val	missense_variant	0.93	isoniazid
inhA	1674450	c.249G>C	synonymous_variant	0.93	ethionamide
inhA	1674450	c.249G>C	synonymous_variant	0.93	isoniazid
inhA	1674452	p.Ala84Glu	missense_variant	0.93	ethionamide
inhA	1674452	p.Ala84Glu	missense_variant	0.93	isoniazid
inhA	1674462	c.261G>A	synonymous_variant	0.95	ethionamide
inhA	1674462	c.261G>A	synonymous_variant	0.95	isoniazid
inhA	1674480	c.279T>C	synonymous_variant	0.95	ethionamide
inhA	1674480	c.279T>C	synonymous_variant	0.95	isoniazid
inhA	1674483	c.282G>C	synonymous_variant	0.95	ethionamide
inhA	1674483	c.282G>C	synonymous_variant	0.95	isoniazid
inhA	1674486	c.285T>C	synonymous_variant	0.95	ethionamide
inhA	1674486	c.285T>C	synonymous_variant	0.95	isoniazid
inhA	1674489	c.288G>C	synonymous_variant	0.95	ethionamide
inhA	1674489	c.288G>C	synonymous_variant	0.95	isoniazid
inhA	1674507	c.306G>C	synonymous_variant	0.97	ethionamide
inhA	1674507	c.306G>C	synonymous_variant	0.97	isoniazid
inhA	1674534	c.333G>C	synonymous_variant	0.97	ethionamide
inhA	1674534	c.333G>C	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
inhA	1674542	p.Ala114Glu	missense_variant	0.97	ethionamide
inhA	1674542	p.Ala114Glu	missense_variant	0.97	isoniazid
inhA	1674546	c.345T>C	synonymous_variant	0.96	ethionamide
inhA	1674546	c.345T>C	synonymous_variant	0.96	isoniazid
inhA	1674549	c.348G>C	synonymous_variant	0.96	ethionamide
inhA	1674549	c.348G>C	synonymous_variant	0.96	isoniazid
inhA	1674550	p.Ser117Ala	missense_variant	0.96	ethionamide
inhA	1674550	p.Ser117Ala	missense_variant	0.96	isoniazid
inhA	1674573	c.372G>C	synonymous_variant	0.98	ethionamide
inhA	1674573	c.372G>C	synonymous_variant	0.98	isoniazid
inhA	1674576	c.375T>C	synonymous_variant	0.98	ethionamide
inhA	1674576	c.375T>C	synonymous_variant	0.98	isoniazid
inhA	1674579	c.378G>C	synonymous_variant	0.98	ethionamide
inhA	1674579	c.378G>C	synonymous_variant	0.98	isoniazid
inhA	1674585	c.384T>C	synonymous_variant	0.98	ethionamide
inhA	1674585	c.384T>C	synonymous_variant	0.98	isoniazid
inhA	1674589	p.Met130Leu	missense_variant	0.98	ethionamide
inhA	1674589	p.Met130Leu	missense_variant	0.98	isoniazid
inhA	1674594	c.393C>T	synonymous_variant	0.97	ethionamide
inhA	1674594	c.393C>T	synonymous_variant	0.97	isoniazid
inhA	1674597	c.396G>A	synonymous_variant	0.97	ethionamide
inhA	1674597	c.396G>A	synonymous_variant	0.97	isoniazid
inhA	1674601	c.400_402delCTGinsGT	frameshift_variant&missense_variant	0.98	ethionamide
inhA	1674601	c.400_402delCTGinsGT	frameshift_variant&missense_variant	0.98	isoniazid
inhA	1674624	c.423A>C	synonymous_variant	0.98	ethionamide
inhA	1674624	c.423A>C	synonymous_variant	0.98	isoniazid
inhA	1674627	c.426T>C	synonymous_variant	0.98	ethionamide
inhA	1674627	c.426T>C	synonymous_variant	0.98	isoniazid
inhA	1674628	p.Ser143Gly	missense_variant	0.98	ethionamide
inhA	1674628	p.Ser143Gly	missense_variant	0.98	isoniazid
inhA	1674656	p.Ser152Thr	missense_variant	0.98	ethionamide
inhA	1674656	p.Ser152Thr	missense_variant	0.98	isoniazid
inhA	1674663	c.462G>A	synonymous_variant	0.98	ethionamide
inhA	1674663	c.462G>A	synonymous_variant	0.98	isoniazid
inhA	1674690	c.489C>G	synonymous_variant	0.98	ethionamide
inhA	1674690	c.489C>G	synonymous_variant	0.98	isoniazid
inhA	1674699	c.498C>T	synonymous_variant	0.99	ethionamide
inhA	1674699	c.498C>T	synonymous_variant	0.99	isoniazid
inhA	1674702	c.501G>C	synonymous_variant	0.99	ethionamide
inhA	1674702	c.501G>C	synonymous_variant	0.99	isoniazid
inhA	1674703	c.502T>C	synonymous_variant	0.99	ethionamide
inhA	1674703	c.502T>C	synonymous_variant	0.99	isoniazid
inhA	1674714	c.513C>G	synonymous_variant	0.98	ethionamide
inhA	1674714	c.513C>G	synonymous_variant	0.98	isoniazid
inhA	1674718	c.517A>C	synonymous_variant	0.98	ethionamide
inhA	1674718	c.517A>C	synonymous_variant	0.98	isoniazid
inhA	1674745	p.Tyr182Val	missense_variant	0.99	ethionamide
inhA	1674745	p.Tyr182Val	missense_variant	0.99	isoniazid
inhA	1674750	c.549T>A	synonymous_variant	0.99	ethionamide	Not assoc w R - Interim
inhA	1674750	c.549T>A	synonymous_variant	0.99	isoniazid	Not assoc w R - Interim
inhA	1674756	c.555T>A	synonymous_variant	0.99	ethionamide
inhA	1674756	c.555T>A	synonymous_variant	0.99	isoniazid
inhA	1674765	c.564C>G	synonymous_variant	0.99	ethionamide
inhA	1674765	c.564C>G	synonymous_variant	0.99	isoniazid
inhA	1674771	c.570C>G	synonymous_variant	0.98	ethionamide
inhA	1674771	c.570C>G	synonymous_variant	0.98	isoniazid
inhA	1674774	c.573A>C	synonymous_variant	0.98	ethionamide
inhA	1674774	c.573A>C	synonymous_variant	0.98	isoniazid
inhA	1674777	c.576C>G	synonymous_variant	0.98	ethionamide
inhA	1674777	c.576C>G	synonymous_variant	0.98	isoniazid
inhA	1674780	c.579T>G	synonymous_variant	0.98	ethionamide
inhA	1674780	c.579T>G	synonymous_variant	0.98	isoniazid
inhA	1674801	c.600T>C	synonymous_variant	0.98	ethionamide
inhA	1674801	c.600T>C	synonymous_variant	0.98	isoniazid
inhA	1674804	c.603G>C	synonymous_variant	0.98	ethionamide	Not assoc w R - Interim
inhA	1674804	c.603G>C	synonymous_variant	0.98	isoniazid
inhA	1674810	c.609C>G	synonymous_variant	0.98	ethionamide
inhA	1674810	c.609C>G	synonymous_variant	0.98	isoniazid
inhA	1674819	c.618G>C	synonymous_variant	0.98	ethionamide
inhA	1674819	c.618G>C	synonymous_variant	0.98	isoniazid
inhA	1674825	c.624C>T	synonymous_variant	0.97	ethionamide
inhA	1674825	c.624C>T	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
inhA	1674828	c.627G>A	synonymous_variant	0.98	ethionamide
inhA	1674828	c.627G>A	synonymous_variant	0.98	isoniazid
inhA	1674830	p.Glu210Gly	missense_variant	0.98	ethionamide
inhA	1674830	p.Glu210Gly	missense_variant	0.98	isoniazid
inhA	1674839	p.Ala213Glu	missense_variant	0.98	ethionamide
inhA	1674839	p.Ala213Glu	missense_variant	0.98	isoniazid
inhA	1674848	p.Gln216Arg	missense_variant	0.97	ethionamide
inhA	1674848	p.Gln216Arg	missense_variant	0.97	isoniazid	Uncertain significance
inhA	1674855	c.654C>G	synonymous_variant	0.96	ethionamide
inhA	1674855	c.654C>G	synonymous_variant	0.96	isoniazid	Not assoc w R - Interim
inhA	1674858	c.657G>A	synonymous_variant	0.96	ethionamide
inhA	1674858	c.657G>A	synonymous_variant	0.96	isoniazid
inhA	1674870	c.669T>C	synonymous_variant	0.96	ethionamide
inhA	1674870	c.669T>C	synonymous_variant	0.96	isoniazid
inhA	1674876	c.675C>G	synonymous_variant	0.96	ethionamide
inhA	1674876	c.675C>G	synonymous_variant	0.96	isoniazid
inhA	1674879	c.678T>C	synonymous_variant	0.95	ethionamide
inhA	1674879	c.678T>C	synonymous_variant	0.95	isoniazid
inhA	1674892	p.Asn231Asp	missense_variant	0.94	ethionamide	Uncertain significance
inhA	1674892	p.Asn231Asp	missense_variant	0.94	isoniazid	Uncertain significance
inhA	1674903	c.702T>C	synonymous_variant	0.91	ethionamide
inhA	1674903	c.702T>C	synonymous_variant	0.91	isoniazid
inhA	1674904	p.Ala235Pro	missense_variant	0.9	ethionamide
inhA	1674904	p.Ala235Pro	missense_variant	0.9	isoniazid
inhA	1674915	c.714C>G	synonymous_variant	0.89	ethionamide
inhA	1674915	c.714C>G	synonymous_variant	0.89	isoniazid
inhA	1674924	c.723G>C	synonymous_variant	0.91	ethionamide
inhA	1674924	c.723G>C	synonymous_variant	0.91	isoniazid
inhA	1674927	c.726G>C	synonymous_variant	0.9	ethionamide
inhA	1674927	c.726G>C	synonymous_variant	0.9	isoniazid
rpsA	1833540	c.-2_-1delATinsC	upstream_gene_variant	1.0	pyrazinamide
rpsA	1833547	c.6G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1833589	c.48A>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833595	c.54T>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833596	p.Ser19Ala	missense_variant	1.0	pyrazinamide
rpsA	1833616	c.75A>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833619	c.78A>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833661	c.120A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833664	c.123C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833667	c.126C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833676	c.135A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833679	c.138G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833694	c.153G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833697	c.156C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833709	c.168C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833724	c.183C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833734	p.Ala65Ser	missense_variant	1.0	pyrazinamide
rpsA	1833770	p.Asn77His	missense_variant	1.0	pyrazinamide
rpsA	1833778	c.237C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833781	c.240T>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833793	c.252C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833802	c.261A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833811	c.270G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833814	c.273C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833820	c.279G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1833835	c.294C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833838	c.297G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833862	c.321G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1833886	c.345C>G	synonymous_variant	0.99	pyrazinamide
rpsA	1833892	c.351G>A	synonymous_variant	0.99	pyrazinamide
rpsA	1833894	p.Ala118Glu	missense_variant	0.99	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1833949	c.408T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1833970	c.429G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833988	c.447C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834015	c.474G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834042	c.501G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1834051	c.510G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1834105	c.564C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834150	c.609G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834153	c.612T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834154	c.613_615delAACinsCG	frameshift_variant&missense_variant	0.99	pyrazinamide	Uncertain significance
rpsA	1834157	c.616T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834162	c.621A>G	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
rpsA	1834165	c.624A>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834169	p.Thr210Ala	missense_variant	0.99	pyrazinamide	Uncertain significance
rpsA	1834172	p.Ile211Val	missense_variant	0.99	pyrazinamide
rpsA	1834177	c.636A>C	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
rpsA	1834189	c.648G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834222	c.681T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834225	c.684C>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834240	c.699T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834264	c.723G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834294	c.753G>T	synonymous_variant	0.99	pyrazinamide
rpsA	1834297	c.756C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834303	c.762T>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834361	c.820T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834366	c.825A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834375	c.834G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834396	c.855G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834411	c.870T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834423	c.882G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834432	c.891G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834456	c.915T>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834468	c.927A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834489	c.948T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834498	c.957C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834522	c.981C>T	synonymous_variant	0.99	pyrazinamide
rpsA	1834527	p.Arg329His	missense_variant	0.99	pyrazinamide
rpsA	1834540	c.999G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834543	c.1002C>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834546	c.1005T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834552	c.1011G>T	synonymous_variant	0.99	pyrazinamide
rpsA	1834573	c.1032G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834603	p.Glu354Asp	missense_variant	0.99	pyrazinamide
rpsA	1834609	c.1068T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834619	c.1078T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834622	c.1081_1083delTCGinsAGC	synonymous_variant	0.99	pyrazinamide
rpsA	1834633	c.1092A>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834639	c.1098T>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834666	c.1125G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834667	p.Ala376Ser	missense_variant	1.0	pyrazinamide
rpsA	1834690	c.1149T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834732	c.1191T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834738	c.1197A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834747	c.1206A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834751	c.1210_1212delCTTinsAC	frameshift_variant&missense_variant	1.0	pyrazinamide	Uncertain significance
rpsA	1834756	c.1215G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1834759	c.1218A>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834765	p.Glu408Asp	missense_variant	1.0	pyrazinamide
rpsA	1834775	p.Ala412Thr	missense_variant	1.0	pyrazinamide
rpsA	1834780	c.1239A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834786	c.1245A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834789	c.1248T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834792	c.1251G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834810	c.1269C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834813	c.1272G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834852	c.1311C>T	synonymous_variant	1.0	pyrazinamide
tsnR	1853361	c.-245T>C	upstream_gene_variant	0.98	linezolid
tsnR	1853370	c.-236_-234delGCAinsTC	upstream_gene_variant	0.98	linezolid
tsnR	1853375	c.-231G>C	upstream_gene_variant	0.98	linezolid
tsnR	1853387	c.-219T>G	upstream_gene_variant	0.98	linezolid
tsnR	1853390	c.-216G>C	upstream_gene_variant	0.97	linezolid
tsnR	1853394	c.-212_-211delCTinsGC	upstream_gene_variant	0.97	linezolid
tsnR	1853420	c.-186T>G	upstream_gene_variant	0.97	linezolid
tsnR	1853429	c.-177G>C	upstream_gene_variant	0.98	linezolid
tsnR	1853432	c.-174G>C	upstream_gene_variant	0.98	linezolid
tsnR	1853435	c.-171G>A	upstream_gene_variant	0.98	linezolid
tsnR	1853444	c.-162C>T	upstream_gene_variant	0.98	linezolid
tsnR	1853459	c.-147G>C	upstream_gene_variant	0.97	linezolid
tsnR	1853462	c.-144A>G	upstream_gene_variant	0.97	linezolid
tsnR	1853474	c.-132C>G	upstream_gene_variant	0.96	linezolid
tsnR	1853477	c.-129T>C	upstream_gene_variant	0.96	linezolid
tsnR	1853480	c.-126G>C	upstream_gene_variant	0.96	linezolid
tsnR	1853481	c.-125A>G	upstream_gene_variant	0.96	linezolid
tsnR	1853490	c.-116C>G	upstream_gene_variant	0.96	linezolid
tsnR	1853495	c.-111G>T	upstream_gene_variant	0.96	linezolid
tsnR	1853498	c.-108G>A	upstream_gene_variant	0.96	linezolid
tsnR	1853516	c.-90C>G	upstream_gene_variant	0.91	linezolid
tsnR	1853522	c.-84C>T	upstream_gene_variant	0.91	linezolid
tsnR	1853528	c.-78G>C	upstream_gene_variant	0.88	linezolid
tsnR	1853531	c.-75A>G	upstream_gene_variant	0.86	linezolid
tsnR	1853540	c.-66A>G	upstream_gene_variant	0.83	linezolid
tsnR	1853543	c.-63C>T	upstream_gene_variant	0.8	linezolid
ndh	2102302	c.741G>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102308	c.735G>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102317	c.726A>G	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102328	p.Leu239Met	missense_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102337	c.706T>C	synonymous_variant	0.95	ethionamide	Not assoc w R - Interim
					delamanid
					isoniazid
ndh	2102341	p.Ala234Glu	missense_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102344	c.699T>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102347	c.696G>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102353	p.Gln230Arg	missense_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102356	c.687T>A	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102359	c.684C>G	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102365	p.Ala226Glu	missense_variant	0.95	ethionamide
					delamanid
					isoniazid	Uncertain significance
ndh	2102377	c.666A>G	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102386	c.657G>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102389	c.654G>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102392	c.651C>G	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102401	c.642T>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid	Not assoc w R - Interim
ndh	2102407	c.636T>C	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
ndh	2102419	c.624G>A	synonymous_variant	0.95	ethionamide
					delamanid
					isoniazid
kasA	2517917	c.-198G>T	upstream_gene_variant	1.0	isoniazid
kasA	2517926	c.-189G>A	upstream_gene_variant	1.0	isoniazid
kasA	2517941	c.-174C>G	upstream_gene_variant	0.99	isoniazid
kasA	2517950	c.-165C>G	upstream_gene_variant	0.99	isoniazid
kasA	2517974	c.-141T>C	upstream_gene_variant	0.97	isoniazid
kasA	2517989	c.-126T>G	upstream_gene_variant	0.96	isoniazid
kasA	2517992	c.-123C>G	upstream_gene_variant	0.96	isoniazid
kasA	2517994	c.-121C>G	upstream_gene_variant	0.96	isoniazid
kasA	2518219	c.105T>C	synonymous_variant	0.94	isoniazid
kasA	2518220	c.106C>T	synonymous_variant	0.94	isoniazid
kasA	2518223	c.109_111delTTGinsCC	frameshift_variant&missense_variant	0.94	isoniazid
kasA	2518231	c.117C>T	synonymous_variant	0.96	isoniazid
kasA	2518243	c.129C>T	synonymous_variant	0.97	isoniazid
kasA	2518248	p.Ala45Val	missense_variant	0.97	isoniazid
kasA	2518269	p.Thr52Ser	missense_variant	0.97	isoniazid
kasA	2518279	c.165T>C	synonymous_variant	0.97	isoniazid
kasA	2518282	c.168A>G	synonymous_variant	0.97	isoniazid
kasA	2518283	p.Ala57Pro	missense_variant	0.97	isoniazid
kasA	2518300	c.186T>C	synonymous_variant	0.98	isoniazid
kasA	2518304	c.190_192delCTCinsTG	frameshift_variant&missense_variant	0.97	isoniazid
kasA	2518322	p.Ser70Asp	missense_variant	0.98	isoniazid
kasA	2518336	c.222A>G	synonymous_variant	0.98	isoniazid
kasA	2518339	c.225C>G	synonymous_variant	0.98	isoniazid
kasA	2518357	c.243G>C	synonymous_variant	0.97	isoniazid
kasA	2518374	p.Gly87Ala	missense_variant	0.96	isoniazid
kasA	2518379	c.265T>C	synonymous_variant	0.93	isoniazid
kasA	2518462	c.348A>G	synonymous_variant	1.0	isoniazid
kasA	2518465	c.351T>C	synonymous_variant	0.93	isoniazid
kasA	2518468	c.354A>T	synonymous_variant	1.0	isoniazid
kasA	2518470	p.Ala119Gly	missense_variant	1.0	isoniazid
kasA	2518480	c.366T>C	synonymous_variant	1.0	isoniazid
kasA	2518488	p.Ser125Thr	missense_variant	0.98	isoniazid
kasA	2518492	c.378C>T	synonymous_variant	0.98	isoniazid
kasA	2518504	c.390T>C	synonymous_variant	0.98	isoniazid
kasA	2518506	p.Ala131Glu	missense_variant	0.98	isoniazid
kasA	2518519	c.405G>C	synonymous_variant	0.99	isoniazid
kasA	2518528	c.414C>G	synonymous_variant	0.99	isoniazid
kasA	2518564	c.450C>G	synonymous_variant	0.99	isoniazid
kasA	2518567	c.453G>C	synonymous_variant	0.99	isoniazid
kasA	2518574	p.Ile154Val	missense_variant	0.99	isoniazid
kasA	2518579	c.465T>C	synonymous_variant	0.99	isoniazid
kasA	2518588	c.474T>C	synonymous_variant	0.99	isoniazid
kasA	2518591	c.477G>C	synonymous_variant	0.99	isoniazid
kasA	2518594	c.480C>T	synonymous_variant	0.99	isoniazid
kasA	2518606	c.492G>C	synonymous_variant	0.99	isoniazid
kasA	2518609	p.Met165Ile	missense_variant	0.99	isoniazid
kasA	2518636	c.522C>T	synonymous_variant	1.0	isoniazid
kasA	2518642	c.528A>G	synonymous_variant	1.0	isoniazid
kasA	2518648	c.534C>T	synonymous_variant	1.0	isoniazid
kasA	2518651	c.537C>G	synonymous_variant	1.0	isoniazid
kasA	2518672	c.558G>C	synonymous_variant	0.99	isoniazid
kasA	2518684	c.570C>G	synonymous_variant	0.99	isoniazid
kasA	2518688	p.Val192Phe	missense_variant	0.99	isoniazid
kasA	2518693	c.579C>G	synonymous_variant	0.99	isoniazid
kasA	2518714	c.600A>C	synonymous_variant	0.99	isoniazid
kasA	2518715	p.Pro201Gly	missense_variant	0.99	isoniazid
kasA	2518726	c.612G>A	synonymous_variant	0.99	isoniazid
kasA	2518732	c.618C>G	synonymous_variant	0.99	isoniazid
kasA	2518747	c.633C>G	synonymous_variant	0.99	isoniazid
kasA	2518756	c.642G>C	synonymous_variant	0.99	isoniazid
kasA	2518759	c.645C>G	synonymous_variant	0.99	isoniazid
kasA	2518780	p.Glu222Asp	missense_variant	0.98	isoniazid
kasA	2518783	c.669T>C	synonymous_variant	0.98	isoniazid
kasA	2518787	c.673_675delCGGinsGT	frameshift_variant&missense_variant	0.98	isoniazid
kasA	2518792	c.678C>G	synonymous_variant	0.98	isoniazid
kasA	2518795	c.681C>G	synonymous_variant	0.98	isoniazid
kasA	2518811	p.Asp233Asn	missense_variant	0.98	isoniazid
kasA	2518816	c.702C>G	synonymous_variant	0.98	isoniazid
kasA	2518825	c.711T>C	synonymous_variant	0.98	isoniazid
kasA	2518828	c.714G>C	synonymous_variant	0.98	isoniazid
kasA	2518834	c.720C>T	synonymous_variant	0.98	isoniazid
kasA	2518837	c.723G>A	synonymous_variant	0.97	isoniazid
kasA	2518843	c.729T>C	synonymous_variant	0.97	isoniazid
kasA	2518853	p.Leu247Ile	missense_variant	0.97	isoniazid
kasA	2518864	c.750G>C	synonymous_variant	0.96	isoniazid
kasA	2518879	c.765A>G	synonymous_variant	0.97	isoniazid
kasA	2518882	c.768C>A	synonymous_variant	0.96	isoniazid
kasA	2518885	c.771T>C	synonymous_variant	0.96	isoniazid
kasA	2518898	c.784T>C	synonymous_variant	0.94	isoniazid
ahpC	2726564	c.372C>G	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
ahpC	2726571	p.Ala127Ser	missense_variant	1.0	isoniazid
ahpC	2726579	c.387T>C	synonymous_variant	1.0	isoniazid
ahpC	2726582	c.390G>C	synonymous_variant	1.0	isoniazid
ahpC	2726591	c.399C>G	synonymous_variant	1.0	isoniazid
ahpC	2726593	p.Val134Ala	missense_variant	1.0	isoniazid
ahpC	2726600	c.408T>C	synonymous_variant	1.0	isoniazid
ahpC	2726604	p.Val138Ile	missense_variant	1.0	isoniazid
ahpC	2726624	c.432C>T	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
ahpC	2726638	p.Ala149Val	missense_variant	0.9	isoniazid
ahpC	2726642	c.450C>G	synonymous_variant	0.9	isoniazid
ahpC	2726645	c.453C>G	synonymous_variant	0.9	isoniazid
ahpC	2726657	c.465A>C	synonymous_variant	0.9	isoniazid	Not assoc w R - Interim
ahpC	2726669	c.477T>C	synonymous_variant	0.9	isoniazid
ahpC	2726675	c.483A>G	synonymous_variant	0.9	isoniazid
ahpC	2726681	c.489A>G	synonymous_variant	0.9	isoniazid
ahpC	2726687	c.495C>G	synonymous_variant	0.9	isoniazid
ahpC	2726696	c.504C>G	synonymous_variant	0.9	isoniazid
folC	2746987	c.612T>C	synonymous_variant	0.92	para-aminosalicylic_acid
folC	2746999	c.600T>C	synonymous_variant	0.96	para-aminosalicylic_acid
folC	2747002	c.597T>C	synonymous_variant	0.97	para-aminosalicylic_acid
folC	2747007	p.Ser198Gly	missense_variant	0.97	para-aminosalicylic_acid
folC	2747032	c.567A>T	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747037	p.Asn188Asp	missense_variant	0.98	para-aminosalicylic_acid
folC	2747038	c.559_561delATCinsGG	frameshift_variant&missense_variant	0.98	para-aminosalicylic_acid
folC	2747041	c.558G>C	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747059	c.540T>C	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747062	c.537A>T	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747074	c.525G>C	synonymous_variant	0.96	para-aminosalicylic_acid
folC	2747077	c.522G>A	synonymous_variant	0.96	para-aminosalicylic_acid
folC	2747080	c.519C>G	synonymous_variant	0.96	para-aminosalicylic_acid
folC	2747083	c.514_516delGTGinsAT	frameshift_variant&missense_variant	0.96	para-aminosalicylic_acid
folC	2747086	c.513A>C	synonymous_variant	0.96	para-aminosalicylic_acid
folC	2747089	c.510G>C	synonymous_variant	0.96	para-aminosalicylic_acid
folC	2747101	c.498G>C	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747107	c.492G>C	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747110	c.489T>C	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747113	c.486C>G	synonymous_variant	0.98	para-aminosalicylic_acid
folC	2747129	p.Ala157Gly	missense_variant	0.98	para-aminosalicylic_acid
folC	2747140	c.459G>A	synonymous_variant	0.97	para-aminosalicylic_acid
Rv2477c	2782431	p.Glu538Gln	missense_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782453	c.1590C>T	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782483	c.1560G>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782522	c.1521G>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782528	c.1515G>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782537	c.1506T>C	synonymous_variant	0.95	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782540	c.1503T>C	synonymous_variant	0.95	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782549	c.1494T>C	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2782555	c.1486_1488delTCGinsAGC	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782558	c.1485T>C	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782561	c.1482G>C	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782582	c.1459_1461delAACinsCG	frameshift_variant&missense_variant	0.94	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2782586	p.Leu486Glu	missense_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782588	c.1455G>C	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782591	c.1452T>C	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782594	c.1449T>C	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782606	c.1437T>C	synonymous_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782609	c.1434G>C	synonymous_variant	0.86	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2782612	c.1431T>A	synonymous_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782615	c.1428G>A	synonymous_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782633	c.1410G>C	synonymous_variant	0.84	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782894	c.1149C>G	synonymous_variant	0.77	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782903	c.1140C>A	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782912	p.Ser377Thr	missense_variant	0.87	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782927	p.Thr372Glu	missense_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782930	c.1113G>A	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782933	c.1110C>G	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782936	c.1107G>T	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782945	c.1098C>G	synonymous_variant	0.81	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2782948	c.1095A>G	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782957	c.1086A>G	synonymous_variant	0.81	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2782960	c.1083C>G	synonymous_variant	0.76	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782969	c.1074A>C	synonymous_variant	0.76	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782972	c.1071G>C	synonymous_variant	0.76	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782981	c.1062G>C	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782984	c.1059T>C	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782987	c.1056C>G	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783002	c.1041T>C	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783008	c.1035C>G	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783013	c.1030T>C	synonymous_variant	0.81	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783014	p.Ser343Thr	missense_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783299	c.744A>G	synonymous_variant	0.91	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783302	c.741A>G	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783311	c.732T>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783317	c.726G>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783332	c.711T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783350	c.693T>C	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783353	c.690T>C	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783371	c.672A>G	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783374	c.669G>C	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783386	c.657G>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783413	c.630G>C	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2783419	c.624G>C	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783422	c.621T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783425	c.618C>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783432	c.610_611delAGinsTC	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783440	c.603T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783446	c.597A>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783456	p.Gln196Leu	missense_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783461	c.582T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783464	c.579A>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783467	c.576G>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783473	c.570A>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783494	c.549C>G	synonymous_variant	0.95	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783497	c.544_546delTTGinsCC	frameshift_variant&missense_variant	0.95	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2783502	c.541T>C	synonymous_variant	0.99	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783509	c.534C>T	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783512	c.531A>G	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783516	c.526_527delTCinsAG	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783520	c.523T>C	synonymous_variant	0.99	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2783527	c.516A>G	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783545	c.498C>G	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783548	c.495T>C	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783563	c.480A>C	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783568	p.Asn159His	missense_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783572	c.471A>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783575	c.468G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783593	c.450T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783605	c.438T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783611	c.432C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783617	c.426G>A	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783628	p.Ala139Ser	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783634	p.Leu137Ile	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783641	c.402G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783651	p.His131Ala	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783656	c.387G>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783659	c.384A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783665	c.378A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783672	p.Arg124Lys	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783674	c.369T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783683	c.360A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783718	c.325T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783719	c.324A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783805	p.Asn80Asp	missense_variant	0.87	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783815	c.228A>G	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783821	p.Gln74Leu	missense_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783833	c.210G>C	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783836	c.207C>G	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783847	p.Thr66Pro	missense_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783848	c.195C>G	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783857	c.186C>T	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783860	c.183T>C	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783874	p.Pro57Ala	missense_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783883	c.160T>C	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783884	c.159T>G	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783887	c.156C>T	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783901	c.142T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783908	c.135G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783917	c.126C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783920	c.123G>T	synonymous_variant	0.98	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2783953	c.90G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783956	p.Tyr29Leu	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783962	p.Ser27Asn	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783967	c.76T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783971	c.72G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783986	c.57G>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783989	c.54G>A	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783992	c.51T>C	synonymous_variant	0.98	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2784001	c.42G>A	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784004	c.39G>A	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784010	c.33C>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784047	c.-5G>C	upstream_gene_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784053	c.-11A>G	upstream_gene_variant	0.8	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2752c	3065052	c.1140G>A	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065055	c.1137T>C	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065060	p.Ala378Ser	missense_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065064	c.1128G>C	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065070	c.1122C>G	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065082	c.1110G>T	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065085	c.1105_1107delAGGinsCC	frameshift_variant&missense_variant	0.92	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065088	c.1104A>G	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065091	c.1101A>G	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065097	c.1095C>T	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065106	c.1086C>G	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065109	c.1081_1083delAGAinsCG	frameshift_variant&missense_variant	0.92	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065115	c.1077C>T	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065126	p.Ser356Ala	missense_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065133	c.1059T>C	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065136	p.Ile352Met	missense_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065139	c.1053C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065142	c.1050A>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065146	p.Phe349Tyr	missense_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065151	c.1041G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065154	c.1038G>A	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065169	c.1023C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065972	p.Ile74Val	missense_variant	0.96	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065979	c.213T>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065990	p.Glu68Gln	missense_variant	0.97	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065993	p.Val67Ile	missense_variant	0.97	ethambutol	Uncertain significance
					moxifloxacin
					levofloxacin
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065994	c.198T>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065997	c.195C>G	synonymous_variant	0.97	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066000	p.Met64Ile	missense_variant	0.97	ethambutol	Uncertain significance
					moxifloxacin
					levofloxacin
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3066018	c.174T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066024	c.168T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066042	c.150T>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066045	c.147T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066050	c.142T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066054	c.138T>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066066	c.126T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066071	c.121T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066075	c.117A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066078	c.114C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066081	c.111G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066087	c.105A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3066096	c.96G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066118	p.Asn25Ser	missense_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066123	c.69C>T	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3066129	c.63G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066141	c.51G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066146	c.46T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
thyX	3067355	c.591A>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067373	c.573C>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067382	c.564C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067388	c.558C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067400	c.546C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067406	c.540A>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067427	c.519G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067430	c.516C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067433	c.513C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067457	c.489C>G	synonymous_variant	0.98	para-aminosalicylic_acid
thyX	3067463	c.481_483delATCinsGG	frameshift_variant&missense_variant	0.98	para-aminosalicylic_acid
thyX	3067469	c.477C>T	synonymous_variant	0.98	para-aminosalicylic_acid
thyX	3067475	c.471A>G	synonymous_variant	0.98	para-aminosalicylic_acid
thyX	3067481	c.465C>A	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067487	c.459G>A	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067496	c.450G>A	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067500	p.Lys149Arg	missense_variant	0.94	para-aminosalicylic_acid
thyX	3067799	c.147G>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067802	c.144C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067814	c.132T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067826	c.120C>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067838	c.108C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067843	c.103C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067844	c.102G>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067847	c.97_99delCCCinsTG	frameshift_variant&missense_variant	1.0	para-aminosalicylic_acid
thyX	3067850	c.96A>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067869	p.Thr26Ser	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067874	c.72C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067883	c.63C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067886	c.60A>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067889	c.55_57delGCCinsCG	frameshift_variant&synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067892	p.Leu18Ser	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067898	p.Asp16Glu	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067910	c.36C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067934	c.12C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067949	c.-4C>T	upstream_gene_variant	1.0	para-aminosalicylic_acid
thyA	3073845	c.627C>T	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073863	c.609T>C	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3073881	c.591C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073887	p.Ser195Gly	missense_variant	0.97	para-aminosalicylic_acid
thyA	3073892	c.580T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073893	c.579C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073896	c.576C>T	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073902	c.570C>G	synonymous_variant	0.98	para-aminosalicylic_acid
thyA	3073920	c.552C>G	synonymous_variant	0.98	para-aminosalicylic_acid
thyA	3073925	c.547T>C	synonymous_variant	0.98	para-aminosalicylic_acid
thyA	3073947	c.525G>A	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073953	c.519T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073956	c.516G>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073959	c.513T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073971	c.501C>T	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073977	c.495A>G	synonymous_variant	0.98	para-aminosalicylic_acid
thyA	3073980	c.492C>T	synonymous_variant	0.98	para-aminosalicylic_acid
thyA	3073989	c.483T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073993	c.478_479delAGinsTC	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3073999	p.Arg158Lys	missense_variant	0.97	para-aminosalicylic_acid
thyA	3074004	c.468T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3074013	c.459C>T	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3074025	c.445_447delTTCinsCG	frameshift_variant&missense_variant	0.97	para-aminosalicylic_acid
thyA	3074031	c.441T>C	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074040	c.430_432delCCGinsGC	frameshift_variant&missense_variant	0.94	para-aminosalicylic_acid
thyA	3074052	c.419_420insA	frameshift_variant	0.87	para-aminosalicylic_acid
thyA	3074055	c.416delA	frameshift_variant	0.85	para-aminosalicylic_acid
thyA	3074061	c.411A>G	synonymous_variant	0.88	para-aminosalicylic_acid
thyA	3074263	p.Gly70Ala	missense_variant	0.91	para-aminosalicylic_acid
thyA	3074268	c.204T>C	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074274	c.198T>C	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074277	c.195C>T	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074285	c.187T>C	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074305	p.Ala56Ile	missense_variant	0.94	para-aminosalicylic_acid
thyA	3074307	c.165A>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074313	c.159A>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074318	p.Phe52Leu	missense_variant	0.94	para-aminosalicylic_acid
thyA	3074319	c.153T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3074322	c.150C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3074325	c.147A>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3074334	c.138T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyA	3074339	p.Leu45Ile	missense_variant	1.0	para-aminosalicylic_acid
thyA	3074349	c.123T>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074355	c.115_117delTCGinsGC	frameshift_variant&missense_variant	1.0	para-aminosalicylic_acid
thyA	3074360	c.112T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074361	c.111T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074372	p.Met34Leu	missense_variant	1.0	para-aminosalicylic_acid
thyA	3074376	p.Gln32His	missense_variant	1.0	para-aminosalicylic_acid
thyA	3074397	c.75A>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074409	c.63C>T	synonymous_variant	1.0	para-aminosalicylic_acid
lpqB	3624331	c.580C>T	synonymous_variant	0.75	bedaquiline
lpqB	3624331	c.580C>T	synonymous_variant	0.75	rifampicin
lpqB	3624339	p.Arg191Pro	missense_variant	0.83	bedaquiline
lpqB	3624339	p.Arg191Pro	missense_variant	0.83	rifampicin
lpqB	3624341	c.570C>T	synonymous_variant	0.85	bedaquiline
lpqB	3624341	c.570C>T	synonymous_variant	0.85	rifampicin
lpqB	3624353	c.558C>T	synonymous_variant	0.92	bedaquiline
lpqB	3624353	c.558C>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
lpqB	3624362	c.549G>C	synonymous_variant	0.93	bedaquiline
lpqB	3624362	c.549G>C	synonymous_variant	0.93	rifampicin
lpqB	3624377	c.534C>G	synonymous_variant	0.95	bedaquiline
lpqB	3624377	c.534C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
lpqB	3624380	c.531G>A	synonymous_variant	0.93	bedaquiline
lpqB	3624380	c.531G>A	synonymous_variant	0.93	rifampicin
lpqB	3624389	c.522C>G	synonymous_variant	0.95	bedaquiline
lpqB	3624389	c.522C>G	synonymous_variant	0.95	rifampicin
lpqB	3624392	c.519C>T	synonymous_variant	0.95	bedaquiline	Not assoc w R - Interim
lpqB	3624392	c.519C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
lpqB	3624396	p.Ala172Val	missense_variant	0.93	bedaquiline
lpqB	3624396	p.Ala172Val	missense_variant	0.93	rifampicin
lpqB	3624401	c.510C>T	synonymous_variant	0.93	bedaquiline
lpqB	3624401	c.510C>T	synonymous_variant	0.93	rifampicin
lpqB	3624404	c.507G>C	synonymous_variant	0.93	bedaquiline
lpqB	3624404	c.507G>C	synonymous_variant	0.93	rifampicin
lpqB	3624407	c.504C>G	synonymous_variant	0.93	bedaquiline
lpqB	3624407	c.504C>G	synonymous_variant	0.93	rifampicin
lpqB	3624422	c.489G>C	synonymous_variant	0.93	bedaquiline
lpqB	3624422	c.489G>C	synonymous_variant	0.93	rifampicin
lpqB	3624425	p.Glu162Ala	missense_variant	0.9	bedaquiline
lpqB	3624425	p.Glu162Ala	missense_variant	0.9	rifampicin
lpqB	3624428	c.483A>G	synonymous_variant	0.93	bedaquiline
lpqB	3624428	c.483A>G	synonymous_variant	0.93	rifampicin
lpqB	3624452	c.459T>G	synonymous_variant	0.93	bedaquiline
lpqB	3624452	c.459T>G	synonymous_variant	0.93	rifampicin
lpqB	3624464	c.447A>G	synonymous_variant	0.9	bedaquiline
lpqB	3624464	c.447A>G	synonymous_variant	0.9	rifampicin
lpqB	3624467	c.444C>G	synonymous_variant	0.9	bedaquiline
lpqB	3624467	c.444C>G	synonymous_variant	0.9	rifampicin
lpqB	3624470	c.441T>C	synonymous_variant	0.9	bedaquiline
lpqB	3624470	c.441T>C	synonymous_variant	0.9	rifampicin
lpqB	3624482	c.429T>G	synonymous_variant	0.85	bedaquiline
lpqB	3624482	c.429T>G	synonymous_variant	0.85	rifampicin
lpqB	3624485	c.426T>C	synonymous_variant	0.81	bedaquiline
lpqB	3624485	c.426T>C	synonymous_variant	0.81	rifampicin
lpqB	3624491	c.420G>C	synonymous_variant	0.78	bedaquiline
lpqB	3624491	c.420G>C	synonymous_variant	0.78	rifampicin
lpqB	3624499	p.Val138Leu	missense_variant	0.62	bedaquiline
lpqB	3624499	p.Val138Leu	missense_variant	0.62	rifampicin
lpqB	3624502	c.409T>C	synonymous_variant	0.47	bedaquiline
lpqB	3624502	c.409T>C	synonymous_variant	0.47	rifampicin
lpqB	3624503	c.408G>A	synonymous_variant	0.47	bedaquiline
lpqB	3624503	c.408G>A	synonymous_variant	0.47	rifampicin
lpqB	3625027	c.-117C>G	upstream_gene_variant	0.9	bedaquiline
lpqB	3625027	c.-117C>G	upstream_gene_variant	0.9	rifampicin
lpqB	3625057	c.-147C>T	upstream_gene_variant	0.91	bedaquiline
lpqB	3625057	c.-147C>T	upstream_gene_variant	0.91	rifampicin
mtrB	3625065	p.Met517Leu	missense_variant	1.0	bedaquiline	Uncertain significance
mtrB	3625065	p.Met517Leu	missense_variant	1.0	rifampicin	Not assoc w R
lpqB	3625069	c.-159T>G	upstream_gene_variant	0.91	bedaquiline
lpqB	3625069	c.-159T>G	upstream_gene_variant	0.91	rifampicin
lpqB	3625072	c.-162G>C	upstream_gene_variant	0.91	bedaquiline
lpqB	3625072	c.-162G>C	upstream_gene_variant	0.91	rifampicin
lpqB	3625090	c.-180C>G	upstream_gene_variant	0.91	bedaquiline
lpqB	3625090	c.-180C>G	upstream_gene_variant	0.91	rifampicin
mtrB	3625095	p.Glu507Lys	missense_variant	0.91	bedaquiline
mtrB	3625095	p.Glu507Lys	missense_variant	0.91	rifampicin
lpqB	3625099	c.-189C>G	upstream_gene_variant	0.91	bedaquiline
lpqB	3625099	c.-189C>G	upstream_gene_variant	0.91	rifampicin
lpqB	3625102	c.-192A>G	upstream_gene_variant	0.91	bedaquiline
lpqB	3625102	c.-192A>G	upstream_gene_variant	0.91	rifampicin
lpqB	3625111	c.-201G>C	upstream_gene_variant	0.91	bedaquiline
lpqB	3625111	c.-201G>C	upstream_gene_variant	0.91	rifampicin
lpqB	3625114	c.-204G>A	upstream_gene_variant	0.91	bedaquiline
lpqB	3625114	c.-204G>A	upstream_gene_variant	0.91	rifampicin
lpqB	3625117	c.-207T>G	upstream_gene_variant	0.94	bedaquiline
lpqB	3625117	c.-207T>G	upstream_gene_variant	0.94	rifampicin
lpqB	3625123	c.-213T>C	upstream_gene_variant	0.94	bedaquiline
lpqB	3625123	c.-213T>C	upstream_gene_variant	0.94	rifampicin
lpqB	3625134	c.-224T>C	upstream_gene_variant	0.94	bedaquiline
lpqB	3625134	c.-224T>C	upstream_gene_variant	0.94	rifampicin
mtrB	3625135	c.1479A>G	synonymous_variant	0.94	bedaquiline	Not assoc w R - Interim
mtrB	3625135	c.1479A>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
lpqB	3625141	c.-231T>C	upstream_gene_variant	0.94	bedaquiline
lpqB	3625141	c.-231T>C	upstream_gene_variant	0.94	rifampicin
lpqB	3625147	c.-237C>G	upstream_gene_variant	0.94	bedaquiline
lpqB	3625147	c.-237C>G	upstream_gene_variant	0.94	rifampicin
lpqB	3625161	c.-251T>C	upstream_gene_variant	0.94	bedaquiline
lpqB	3625161	c.-251T>C	upstream_gene_variant	0.94	rifampicin
lpqB	3625162	c.-252T>G	upstream_gene_variant	0.94	bedaquiline
lpqB	3625162	c.-252T>G	upstream_gene_variant	0.94	rifampicin
lpqB	3625174	c.-264C>G	upstream_gene_variant	0.86	bedaquiline
lpqB	3625174	c.-264C>G	upstream_gene_variant	0.86	rifampicin
mtrB	3625177	c.1437C>T	synonymous_variant	0.83	bedaquiline	Not assoc w R - Interim
mtrB	3625177	c.1437C>T	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
lpqB	3625282	c.-372C>G	upstream_gene_variant	0.73	bedaquiline
lpqB	3625282	c.-372C>G	upstream_gene_variant	0.73	rifampicin
lpqB	3625291	c.-381A>G	upstream_gene_variant	0.73	bedaquiline
lpqB	3625291	c.-381A>G	upstream_gene_variant	0.73	rifampicin
lpqB	3625309	c.-399C>T	upstream_gene_variant	0.75	bedaquiline
lpqB	3625309	c.-399C>T	upstream_gene_variant	0.75	rifampicin
mtrB	3625313	p.Arg434Val	missense_variant	0.75	bedaquiline
mtrB	3625313	p.Arg434Val	missense_variant	0.75	rifampicin
mtrB	3625321	c.1293A>G	synonymous_variant	0.75	bedaquiline	Not assoc w R - Interim
mtrB	3625321	c.1293A>G	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
lpqB	3625327	c.-417A>G	upstream_gene_variant	0.75	bedaquiline
lpqB	3625327	c.-417A>G	upstream_gene_variant	0.75	rifampicin
lpqB	3625345	c.-435T>C	upstream_gene_variant	0.8	bedaquiline
lpqB	3625345	c.-435T>C	upstream_gene_variant	0.8	rifampicin
lpqB	3625528	c.-618G>C	upstream_gene_variant	0.94	bedaquiline
lpqB	3625528	c.-618G>C	upstream_gene_variant	0.94	rifampicin
lpqB	3625537	c.-627T>C	upstream_gene_variant	0.97	bedaquiline
lpqB	3625537	c.-627T>C	upstream_gene_variant	0.97	rifampicin
mtrB	3625570	c.1042_1044delACGinsTT	frameshift_variant&missense_variant	0.98	bedaquiline	Uncertain significance
mtrB	3625570	c.1042_1044delACGinsTT	frameshift_variant&missense_variant	0.98	rifampicin	Uncertain significance
lpqB	3625579	c.-669A>G	upstream_gene_variant	0.98	bedaquiline
lpqB	3625579	c.-669A>G	upstream_gene_variant	0.98	rifampicin
lpqB	3625587	c.-677C>T	upstream_gene_variant	0.98	bedaquiline
lpqB	3625587	c.-677C>T	upstream_gene_variant	0.98	rifampicin
lpqB	3625594	c.-684T>C	upstream_gene_variant	0.98	bedaquiline
lpqB	3625594	c.-684T>C	upstream_gene_variant	0.98	rifampicin
mtrB	3625599	p.Met339Leu	missense_variant	0.98	bedaquiline
mtrB	3625599	p.Met339Leu	missense_variant	0.98	rifampicin	Uncertain significance
lpqB	3625602	c.-692T>C	upstream_gene_variant	0.98	bedaquiline
lpqB	3625602	c.-692T>C	upstream_gene_variant	0.98	rifampicin
lpqB	3625603	c.-693G>A	upstream_gene_variant	0.98	bedaquiline
lpqB	3625603	c.-693G>A	upstream_gene_variant	0.98	rifampicin
lpqB	3625606	c.-696C>A	upstream_gene_variant	0.98	bedaquiline
lpqB	3625606	c.-696C>A	upstream_gene_variant	0.98	rifampicin
lpqB	3625609	c.-699C>G	upstream_gene_variant	0.98	bedaquiline
lpqB	3625609	c.-699C>G	upstream_gene_variant	0.98	rifampicin
lpqB	3625612	c.-702G>C	upstream_gene_variant	0.98	bedaquiline
lpqB	3625612	c.-702G>C	upstream_gene_variant	0.98	rifampicin
mtrB	3625623	p.Thr331Ser	missense_variant	0.99	bedaquiline
mtrB	3625623	p.Thr331Ser	missense_variant	0.99	rifampicin
lpqB	3625624	c.-714C>T	upstream_gene_variant	0.99	bedaquiline
lpqB	3625624	c.-714C>T	upstream_gene_variant	0.99	rifampicin
mtrB	3625627	p.Asp329Glu	missense_variant	0.99	bedaquiline
mtrB	3625627	p.Asp329Glu	missense_variant	0.99	rifampicin
mtrB	3625636	p.Ala326Glu	missense_variant	0.99	bedaquiline
mtrB	3625636	p.Ala326Glu	missense_variant	0.99	rifampicin
mtrB	3625648	c.964_966delTATinsCC	frameshift_variant&missense_variant	0.98	bedaquiline	Uncertain significance
mtrB	3625648	c.964_966delTATinsCC	frameshift_variant&missense_variant	0.98	rifampicin	Uncertain significance
mtrB	3625656	c.958T>C	synonymous_variant	0.98	bedaquiline	Not assoc w R - Interim
mtrB	3625656	c.958T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.99	bedaquiline
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.99	rifampicin
lpqB	3625675	c.-765G>C	upstream_gene_variant	0.99	bedaquiline
lpqB	3625675	c.-765G>C	upstream_gene_variant	0.99	rifampicin
lpqB	3625683	c.-773C>T	upstream_gene_variant	0.99	bedaquiline
lpqB	3625683	c.-773C>T	upstream_gene_variant	0.99	rifampicin
lpqB	3625687	c.-777G>C	upstream_gene_variant	0.99	bedaquiline
lpqB	3625687	c.-777G>C	upstream_gene_variant	0.99	rifampicin
lpqB	3625690	c.-780T>C	upstream_gene_variant	0.99	bedaquiline
lpqB	3625690	c.-780T>C	upstream_gene_variant	0.99	rifampicin
mtrB	3625729	c.885A>G	synonymous_variant	1.0	bedaquiline
mtrB	3625729	c.885A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3625747	c.867G>C	synonymous_variant	1.0	bedaquiline
mtrB	3625747	c.867G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3625755	p.Ala287Thr	missense_variant	1.0	bedaquiline
mtrB	3625755	p.Ala287Thr	missense_variant	1.0	rifampicin	Uncertain significance
mtrB	3625761	p.Gln285Glu	missense_variant	1.0	bedaquiline
mtrB	3625761	p.Gln285Glu	missense_variant	1.0	rifampicin	Uncertain significance
mtrB	3625762	c.852A>T	synonymous_variant	1.0	bedaquiline
mtrB	3625762	c.852A>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3625765	c.849C>G	synonymous_variant	1.0	bedaquiline
mtrB	3625765	c.849C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
lpqB	3625768	c.-858G>C	upstream_gene_variant	1.0	bedaquiline
lpqB	3625768	c.-858G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3625806	c.808A>C	synonymous_variant	1.0	bedaquiline
mtrB	3625806	c.808A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3625819	c.795G>A	synonymous_variant	0.99	bedaquiline
mtrB	3625819	c.795G>A	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
mtrB	3625837	c.777C>G	synonymous_variant	0.99	bedaquiline
mtrB	3625837	c.777C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
lpqB	3625852	c.-942A>T	upstream_gene_variant	0.99	bedaquiline
lpqB	3625852	c.-942A>T	upstream_gene_variant	0.99	rifampicin
lpqB	3625861	c.-951C>T	upstream_gene_variant	0.98	bedaquiline
lpqB	3625861	c.-951C>T	upstream_gene_variant	0.98	rifampicin
mtrB	3625867	c.747A>G	synonymous_variant	0.97	bedaquiline
mtrB	3625867	c.747A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
lpqB	3625882	c.-972G>T	upstream_gene_variant	0.96	bedaquiline
lpqB	3625882	c.-972G>T	upstream_gene_variant	0.96	rifampicin
mtrB	3625899	p.Val239Leu	missense_variant	0.94	bedaquiline
mtrB	3625899	p.Val239Leu	missense_variant	0.94	rifampicin
lpqB	3625909	c.-999T>G	upstream_gene_variant	0.94	bedaquiline
lpqB	3625909	c.-999T>G	upstream_gene_variant	0.94	rifampicin
mtrB	3626696	c.-83T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626696	c.-83T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626711	c.-98T>A	upstream_gene_variant	1.0	bedaquiline
mtrB	3626711	c.-98T>A	upstream_gene_variant	1.0	rifampicin
mtrB	3626723	c.-110C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626723	c.-110C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626726	c.-113T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626726	c.-113T>C	upstream_gene_variant	1.0	rifampicin
mtrA	3626729	c.619_621delAAGinsCA	frameshift_variant&missense_variant	1.0	bedaquiline
mtrA	3626729	c.619_621delAAGinsCA	frameshift_variant&missense_variant	1.0	rifampicin
mtrB	3626732	c.-119A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626732	c.-119A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626735	c.-122C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626735	c.-122C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626750	c.-137T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626750	c.-137T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626756	c.-143C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3626756	c.-143C>T	upstream_gene_variant	1.0	rifampicin
mtrA	3626759	c.591T>C	synonymous_variant	1.0	bedaquiline
mtrA	3626759	c.591T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3626774	c.574_576delAGGinsCA	frameshift_variant&missense_variant	1.0	bedaquiline
mtrA	3626774	c.574_576delAGGinsCA	frameshift_variant&missense_variant	1.0	rifampicin
mtrB	3626780	c.-167T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626780	c.-167T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626783	c.-170C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626783	c.-170C>G	upstream_gene_variant	1.0	rifampicin
mtrA	3626786	c.564A>G	synonymous_variant	1.0	bedaquiline
mtrA	3626786	c.564A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3626789	c.561C>T	synonymous_variant	1.0	bedaquiline
mtrA	3626789	c.561C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3626792	c.-179G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626792	c.-179G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626795	c.-182C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3626795	c.-182C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3626798	c.-185T>A	upstream_gene_variant	1.0	bedaquiline
mtrB	3626798	c.-185T>A	upstream_gene_variant	1.0	rifampicin
mtrB	3626804	c.-191A>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626804	c.-191A>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626816	c.-203G>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3626816	c.-203G>T	upstream_gene_variant	1.0	rifampicin
mtrA	3626822	p.Asp176Glu	missense_variant	1.0	bedaquiline
mtrA	3626822	p.Asp176Glu	missense_variant	1.0	rifampicin
mtrB	3626840	c.-227C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626840	c.-227C>G	upstream_gene_variant	1.0	rifampicin
mtrA	3626846	c.504G>A	synonymous_variant	1.0	bedaquiline
mtrA	3626846	c.504G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3626852	c.-239G>A	upstream_gene_variant	0.93	bedaquiline
mtrB	3626852	c.-239G>A	upstream_gene_variant	0.93	rifampicin
mtrB	3626857	c.-244T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626857	c.-244T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626858	c.-245A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626858	c.-245A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626861	c.-248C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626861	c.-248C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626866	c.-253T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626866	c.-253T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626876	c.-263A>G	upstream_gene_variant	0.96	bedaquiline
mtrB	3626876	c.-263A>G	upstream_gene_variant	0.96	rifampicin
mtrB	3626885	c.-272A>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3626885	c.-272A>C	upstream_gene_variant	0.95	rifampicin
mtrB	3626890	c.-277T>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3626890	c.-277T>C	upstream_gene_variant	0.95	rifampicin
mtrB	3626891	c.-278G>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3626891	c.-278G>C	upstream_gene_variant	0.95	rifampicin
mtrA	3626907	p.Asn148Gly	missense_variant	0.95	bedaquiline
mtrA	3626907	p.Asn148Gly	missense_variant	0.95	rifampicin
mtrA	3626909	c.441C>G	synonymous_variant	0.95	bedaquiline
mtrA	3626909	c.441C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
mtrA	3626912	p.Thr146Ser	missense_variant	0.95	bedaquiline
mtrA	3626912	p.Thr146Ser	missense_variant	0.95	rifampicin
mtrB	3626915	c.-302C>G	upstream_gene_variant	0.97	bedaquiline
mtrB	3626915	c.-302C>G	upstream_gene_variant	0.97	rifampicin
mtrB	3626930	c.-317A>G	upstream_gene_variant	0.98	bedaquiline
mtrB	3626930	c.-317A>G	upstream_gene_variant	0.98	rifampicin
mtrA	3626939	p.Glu137Asp	missense_variant	0.99	bedaquiline
mtrA	3626939	p.Glu137Asp	missense_variant	0.99	rifampicin
mtrA	3626942	c.406_408delGTAinsAC	frameshift_variant&missense_variant	0.99	bedaquiline
mtrA	3626942	c.406_408delGTAinsAC	frameshift_variant&missense_variant	0.99	rifampicin
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.99	bedaquiline
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.99	rifampicin
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.99	bedaquiline
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.99	rifampicin
mtrB	3626969	c.-356C>G	upstream_gene_variant	0.97	bedaquiline
mtrB	3626969	c.-356C>G	upstream_gene_variant	0.97	rifampicin
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.97	bedaquiline
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.97	rifampicin
mtrB	3626996	c.-383G>A	upstream_gene_variant	0.98	bedaquiline
mtrB	3626996	c.-383G>A	upstream_gene_variant	0.98	rifampicin
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.98	bedaquiline
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.98	rifampicin
mtrB	3627011	c.-398T>G	upstream_gene_variant	0.96	bedaquiline
mtrB	3627011	c.-398T>G	upstream_gene_variant	0.96	rifampicin
mtrA	3627029	c.321C>T	synonymous_variant	0.97	bedaquiline	Not assoc w R - Interim
mtrA	3627029	c.321C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
mtrB	3627059	c.-446G>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3627059	c.-446G>C	upstream_gene_variant	0.96	rifampicin
mtrB	3627062	c.-449G>A	upstream_gene_variant	0.96	bedaquiline
mtrB	3627062	c.-449G>A	upstream_gene_variant	0.96	rifampicin
mtrA	3627068	c.282T>G	synonymous_variant	0.96	bedaquiline
mtrA	3627068	c.282T>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3627071	c.-458G>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3627071	c.-458G>C	upstream_gene_variant	0.96	rifampicin
mtrA	3627080	c.270T>C	synonymous_variant	0.96	bedaquiline
mtrA	3627080	c.270T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.96	rifampicin
mtrA	3627098	c.252A>C	synonymous_variant	0.95	bedaquiline
mtrA	3627098	c.252A>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
mtrB	3627119	c.-506T>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3627119	c.-506T>C	upstream_gene_variant	0.95	rifampicin
mtrB	3627122	c.-509T>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3627122	c.-509T>G	upstream_gene_variant	0.95	rifampicin
mtrB	3627128	c.-515T>C	upstream_gene_variant	0.94	bedaquiline
mtrB	3627128	c.-515T>C	upstream_gene_variant	0.94	rifampicin
mtrA	3627131	p.Ala73Lys	missense_variant	0.94	bedaquiline
mtrA	3627131	p.Ala73Lys	missense_variant	0.94	rifampicin
mtrB	3627139	c.-526T>C	upstream_gene_variant	0.92	bedaquiline
mtrB	3627139	c.-526T>C	upstream_gene_variant	0.92	rifampicin
mtrA	3627146	c.204C>T	synonymous_variant	0.94	bedaquiline
mtrA	3627146	c.204C>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
mtrB	3627149	c.-536G>C	upstream_gene_variant	0.94	bedaquiline
mtrB	3627149	c.-536G>C	upstream_gene_variant	0.94	rifampicin
mtrB	3627167	c.-554T>C	upstream_gene_variant	0.97	bedaquiline
mtrB	3627167	c.-554T>C	upstream_gene_variant	0.97	rifampicin
mtrA	3627175	c.175C>T	synonymous_variant	0.96	bedaquiline
mtrA	3627175	c.175C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3627181	c.-568T>C	upstream_gene_variant	0.91	bedaquiline
mtrB	3627181	c.-568T>C	upstream_gene_variant	0.91	rifampicin
mtrB	3627182	c.-569T>C	upstream_gene_variant	0.89	bedaquiline
mtrB	3627182	c.-569T>C	upstream_gene_variant	0.89	rifampicin
mtrA	3627187	c.163T>C	synonymous_variant	0.89	bedaquiline
mtrA	3627187	c.163T>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
mtrA	3627188	c.160_162delTTAinsCG	frameshift_variant&missense_variant	0.89	bedaquiline
mtrA	3627188	c.160_162delTTAinsCG	frameshift_variant&missense_variant	0.89	rifampicin
mtrB	3627197	c.-584T>C	upstream_gene_variant	0.9	bedaquiline
mtrB	3627197	c.-584T>C	upstream_gene_variant	0.9	rifampicin
mtrB	3627203	c.-590C>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3627203	c.-590C>G	upstream_gene_variant	0.95	rifampicin
mtrB	3627206	c.-593G>T	upstream_gene_variant	0.95	bedaquiline
mtrB	3627206	c.-593G>T	upstream_gene_variant	0.95	rifampicin
mtrA	3627213	p.Arg46His	missense_variant	0.95	bedaquiline
mtrA	3627213	p.Arg46His	missense_variant	0.95	rifampicin
mtrB	3627224	c.-611G>C	upstream_gene_variant	0.91	bedaquiline
mtrB	3627224	c.-611G>C	upstream_gene_variant	0.91	rifampicin
fbiA	3640692	c.150C>T	synonymous_variant	0.64	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiA	3640701	p.Ile53Met	missense_variant	0.64	clofazimine
					pretomanid
					delamanid
fbiB	3640722	c.-813G>C	upstream_gene_variant	0.79	clofazimine
					pretomanid
					delamanid
fbiB	3640743	c.-792T>C	upstream_gene_variant	0.88	clofazimine
					pretomanid
					delamanid
fbiB	3640758	c.-777G>C	upstream_gene_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiB	3640764	c.-771C>T	upstream_gene_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiA	3640765	p.Pro75Ala	missense_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiA	3640768	p.Gln76Glu	missense_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiB	3640782	c.-753C>A	upstream_gene_variant	0.86	clofazimine
					pretomanid
					delamanid
fbiA	3640785	p.Gln81His	missense_variant	0.86	clofazimine
					pretomanid
					delamanid
fbiB	3640788	c.-747T>C	upstream_gene_variant	0.86	clofazimine
					pretomanid
					delamanid
fbiB	3640797	c.-738T>C	upstream_gene_variant	0.82	clofazimine
					pretomanid
					delamanid
fbiB	3640803	c.-732C>T	upstream_gene_variant	0.86	clofazimine
					pretomanid
					delamanid
fbiA	3640810	p.Gln90Glu	missense_variant	0.86	clofazimine
					pretomanid
					delamanid
fbiB	3640815	c.-720A>G	upstream_gene_variant	0.82	clofazimine
					pretomanid
					delamanid
fbiB	3640816	c.-719C>T	upstream_gene_variant	0.81	clofazimine
					pretomanid
					delamanid
fbiA	3640820	p.Val93Ala	missense_variant	0.81	clofazimine
					pretomanid
					delamanid
fbiB	3640827	c.-708T>C	upstream_gene_variant	0.76	clofazimine
					pretomanid
					delamanid
fbiB	3640830	c.-705C>G	upstream_gene_variant	0.76	clofazimine
					pretomanid
					delamanid
fbiA	3640831	p.Val97Met	missense_variant	0.76	clofazimine
					pretomanid
					delamanid
fbiB	3640839	c.-696C>G	upstream_gene_variant	0.76	clofazimine
					pretomanid
					delamanid
fbiA	3640850	p.Glu103Gly	missense_variant	0.76	clofazimine
					pretomanid
					delamanid
fbiB	3640857	c.-678G>C	upstream_gene_variant	0.76	clofazimine
					pretomanid
					delamanid
fbiB	3640866	c.-669T>C	upstream_gene_variant	0.76	clofazimine
					pretomanid
					delamanid
rpoA	3877473	c.1035A>G	synonymous_variant	0.83	rifampicin
rpoA	3877500	c.1008C>T	synonymous_variant	0.91	rifampicin
rpoA	3877503	p.Ala335Gly	missense_variant	0.89	rifampicin
rpoA	3877507	p.Gly334Ala	missense_variant	0.89	rifampicin
rpoA	3877509	p.Glu333Asp	missense_variant	0.9	rifampicin
rpoA	3877514	p.Thr332Ala	missense_variant	0.91	rifampicin	Uncertain significance
rpoA	3877527	c.981C>T	synonymous_variant	0.96	rifampicin
rpoA	3877533	c.975C>T	synonymous_variant	0.96	rifampicin
rpoA	3877548	c.960C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877553	p.Glu319Gln	missense_variant	0.98	rifampicin
rpoA	3877557	c.951C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877569	c.937_939delCCGinsGC	frameshift_variant&missense_variant	0.99	rifampicin
rpoA	3877587	c.921A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877596	c.912G>C	synonymous_variant	0.99	rifampicin
rpoA	3877613	p.Ile299Val	missense_variant	0.98	rifampicin
rpoA	3877617	c.891G>C	synonymous_variant	0.98	rifampicin
rpoA	3877638	c.870T>G	synonymous_variant	0.98	rifampicin
rpoA	3877656	c.852T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877665	c.843C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877668	c.840A>G	synonymous_variant	0.98	rifampicin
rpoA	3877677	c.831G>T	synonymous_variant	0.98	rifampicin
rpoA	3877680	c.828G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877685	c.823C>T	synonymous_variant	0.97	rifampicin
rpoA	3877686	c.822A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877689	c.819C>G	synonymous_variant	0.97	rifampicin
rpoA	3877692	c.816G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877695	c.813C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877704	c.804G>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877737	c.771G>C	synonymous_variant	0.98	rifampicin
rpoA	3877743	c.765T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877764	c.744C>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3877770	c.738A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3877773	c.735G>C	synonymous_variant	0.98	rifampicin
rpoA	3877776	c.732T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3877782	c.726T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3877785	c.723C>A	synonymous_variant	0.99	rifampicin
rpoA	3877803	c.705G>C	synonymous_variant	0.99	rifampicin
rpoA	3877818	c.690A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3877848	c.660C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877856	c.652T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877866	c.642G>C	synonymous_variant	1.0	rifampicin
rpoA	3877872	c.636C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877875	c.633T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877881	c.627G>C	synonymous_variant	1.0	rifampicin
rpoA	3877893	c.615C>G	synonymous_variant	0.99	rifampicin
rpoA	3877905	c.603A>C	synonymous_variant	0.99	rifampicin
rpoA	3877908	c.600T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3877929	c.577_579delATCinsGG	frameshift_variant&missense_variant	0.99	rifampicin
rpoA	3877962	c.546G>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3877968	c.540C>G	synonymous_variant	0.99	rifampicin
rpoA	3877971	p.Asp179Glu	missense_variant	1.0	rifampicin	Uncertain significance
rpoA	3877974	c.534G>C	synonymous_variant	0.98	rifampicin
rpoA	3877989	c.519A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3878001	c.507A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoA	3878082	c.426T>C	synonymous_variant	0.9	rifampicin
rpoA	3878093	p.Val139Ile	missense_variant	0.95	rifampicin
rpoA	3878094	c.414C>G	synonymous_variant	0.95	rifampicin
rpoA	3878103	c.405A>G	synonymous_variant	0.98	rifampicin
rpoA	3878106	c.402G>C	synonymous_variant	0.98	rifampicin
rpoA	3878118	c.390T>C	synonymous_variant	0.98	rifampicin
rpoA	3878127	c.381G>C	synonymous_variant	1.0	rifampicin
rpoA	3878143	p.Gly122Asp	missense_variant	1.0	rifampicin	Uncertain significance
rpoA	3878157	c.351C>G	synonymous_variant	1.0	rifampicin
rpoA	3878160	c.348C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878175	c.333G>C	synonymous_variant	1.0	rifampicin
rpoA	3878184	c.324C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878187	c.321C>G	synonymous_variant	1.0	rifampicin
rpoA	3878193	c.315T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878197	p.Glu104Ala	missense_variant	1.0	rifampicin	Uncertain significance
rpoA	3878205	c.303T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878217	c.291A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878244	c.264G>A	synonymous_variant	1.0	rifampicin
rpoA	3878247	c.261G>C	synonymous_variant	1.0	rifampicin
rpoA	3878250	c.258C>G	synonymous_variant	1.0	rifampicin
rpoA	3878253	c.255G>C	synonymous_variant	0.99	rifampicin
rpoA	3878264	p.Ser82Gly	missense_variant	1.0	rifampicin
rpoA	3878271	c.237T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3878283	p.Glu75Asp	missense_variant	0.99	rifampicin	Uncertain significance
rpoA	3878298	c.210A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3878304	c.204G>C	synonymous_variant	0.99	rifampicin
rpoA	3878310	c.198G>C	synonymous_variant	0.99	rifampicin
rpoA	3878322	c.186A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3878331	c.177A>G	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3878337	c.171T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoA	3878346	c.162T>C	synonymous_variant	0.99	rifampicin
rpoA	3878358	c.150C>G	synonymous_variant	0.99	rifampicin
rpoA	3878364	c.144A>C	synonymous_variant	0.99	rifampicin
rpoA	3878394	c.114G>T	synonymous_variant	0.98	rifampicin
rpoA	3878400	c.108T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3878403	c.105C>T	synonymous_variant	0.99	rifampicin
rpoA	3878415	c.93C>T	synonymous_variant	0.99	rifampicin
rpoA	3878442	c.66G>C	synonymous_variant	0.98	rifampicin
rpoA	3878451	c.57C>G	synonymous_variant	0.97	rifampicin
rpoA	3878454	c.54A>G	synonymous_variant	0.97	rifampicin
rpoA	3878460	p.Asp16Glu	missense_variant	0.97	rifampicin
rpoA	3878465	p.Thr15Ala	missense_variant	1.0	rifampicin
rpoA	3878466	c.40_42delCTCinsGG	frameshift_variant&missense_variant	1.0	rifampicin
rpoA	3878472	p.Asp12Glu	missense_variant	1.0	rifampicin
rpoA	3878475	c.33G>A	synonymous_variant	1.0	rifampicin
rpoA	3878487	c.21C>G	synonymous_variant	1.0	rifampicin
rpoA	3878490	c.18C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878496	c.12A>G	synonymous_variant	1.0	rifampicin
rpoA	3878818	c.-311G>T	upstream_gene_variant	0.88	rifampicin
rpoA	3878830	c.-325_-323delCTGinsAC	upstream_gene_variant	0.88	rifampicin
rpoA	3878833	c.-326C>G	upstream_gene_variant	0.88	rifampicin
rpoA	3878843	c.-337_-336delCGinsAA	upstream_gene_variant	0.88	rifampicin
rpoA	3878845	c.-338G>C	upstream_gene_variant	0.89	rifampicin
rpoA	3878853	c.-346G>A	upstream_gene_variant	0.95	rifampicin
rpoA	3878873	c.-366G>A	upstream_gene_variant	0.98	rifampicin
rpoA	3878878	c.-371T>C	upstream_gene_variant	0.98	rifampicin	Uncertain significance
rpoA	3878884	c.-377C>G	upstream_gene_variant	0.98	rifampicin
rpoA	3878889	c.-382A>G	upstream_gene_variant	0.98	rifampicin
rpoA	3878893	c.-388_-386delCACinsAG	upstream_gene_variant	0.98	rifampicin
rpoA	3878899	c.-392C>T	upstream_gene_variant	0.98	rifampicin
rpoA	3878909	c.-402A>C	upstream_gene_variant	0.98	rifampicin
rpoA	3878914	c.-407T>C	upstream_gene_variant	0.98	rifampicin	Uncertain significance
rpoA	3878917	c.-410G>C	upstream_gene_variant	0.98	rifampicin
rpoA	3878935	c.-428C>T	upstream_gene_variant	1.0	rifampicin
rpoA	3878938	c.-431T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878947	c.-440G>C	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878956	c.-449G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878962	c.-455G>C	upstream_gene_variant	0.97	rifampicin
rpoA	3878965	c.-458C>T	upstream_gene_variant	0.97	rifampicin	Uncertain significance
rpoA	3878968	c.-461T>C	upstream_gene_variant	0.93	rifampicin	Uncertain significance
rpoA	3878974	c.-469_-467delATCinsGT	upstream_gene_variant	0.93	rifampicin
rpoA	3878977	c.-470C>G	upstream_gene_variant	0.93	rifampicin
rpoA	3878995	c.-488A>G	upstream_gene_variant	0.82	rifampicin
rpoA	3879046	c.-539G>A	upstream_gene_variant	0.94	rifampicin
rpoA	3879049	c.-542A>G	upstream_gene_variant	0.96	rifampicin
rpoA	3879061	c.-554C>T	upstream_gene_variant	0.98	rifampicin
rpoA	3879073	c.-566A>G	upstream_gene_variant	0.98	rifampicin
rpoA	3879079	c.-572A>G	upstream_gene_variant	0.98	rifampicin
rpoA	3879088	c.-581A>C	upstream_gene_variant	0.98	rifampicin
rpoA	3879094	c.-587T>C	upstream_gene_variant	0.98	rifampicin
rpoA	3879097	c.-590C>G	upstream_gene_variant	0.98	rifampicin
rpoA	3879121	c.-614T>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879125	c.-618T>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879127	c.-620T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879136	c.-629A>G	upstream_gene_variant	0.99	rifampicin
rpoA	3879160	c.-653A>G	upstream_gene_variant	0.97	rifampicin
rpoA	3879178	c.-671T>C	upstream_gene_variant	0.97	rifampicin
rpoA	3879184	c.-677G>A	upstream_gene_variant	0.97	rifampicin
rpoA	3879190	c.-683C>A	upstream_gene_variant	0.97	rifampicin
rpoA	3879202	c.-695T>C	upstream_gene_variant	0.96	rifampicin
rpoA	3879229	c.-722A>C	upstream_gene_variant	0.8	rifampicin
rpoA	3879232	c.-725A>G	upstream_gene_variant	0.83	rifampicin
ddn	3986633	c.-211C>G	upstream_gene_variant	0.97	delamanid
ddn	3986633	c.-211C>G	upstream_gene_variant	0.97	pretomanid
ddn	3986636	c.-208C>G	upstream_gene_variant	0.97	delamanid
ddn	3986636	c.-208C>G	upstream_gene_variant	0.97	pretomanid
ddn	3986661	c.-183C>A	upstream_gene_variant	0.97	delamanid
ddn	3986661	c.-183C>A	upstream_gene_variant	0.97	pretomanid
ddn	3986663	c.-180_-177delAGCC	upstream_gene_variant	0.98	delamanid
ddn	3986663	c.-180_-177delAGCC	upstream_gene_variant	0.98	pretomanid
ddn	3986687	c.-157C>T	upstream_gene_variant	0.97	delamanid
ddn	3986687	c.-157C>T	upstream_gene_variant	0.97	pretomanid
ddn	3986696	c.-148G>A	upstream_gene_variant	0.96	delamanid
ddn	3986696	c.-148G>A	upstream_gene_variant	0.96	pretomanid
ddn	3986699	c.-145C>G	upstream_gene_variant	0.96	delamanid
ddn	3986699	c.-145C>G	upstream_gene_variant	0.96	pretomanid
clpC1	4038290	p.Asp805Glu	missense_variant	0.88	pyrazinamide
clpC1	4038293	c.2412G>C	synonymous_variant	0.88	pyrazinamide
clpC1	4038310	p.Val799Leu	missense_variant	0.9	pyrazinamide
clpC1	4038314	c.2391T>C	synonymous_variant	0.9	pyrazinamide
clpC1	4038317	c.2388G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4038320	c.2385G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4038323	c.2380_2382delGTCinsTG	frameshift_variant&synonymous_variant	0.9	pyrazinamide
clpC1	4038329	c.2376G>A	synonymous_variant	0.9	pyrazinamide
clpC1	4038335	c.2370C>G	synonymous_variant	0.93	pyrazinamide
clpC1	4038350	c.2355C>G	synonymous_variant	0.9	pyrazinamide
clpC1	4038356	c.2349T>C	synonymous_variant	0.91	pyrazinamide
clpC1	4038368	c.2337T>C	synonymous_variant	0.88	pyrazinamide
clpC1	4038388	c.2317T>C	synonymous_variant	0.89	pyrazinamide
clpC1	4038392	c.2313C>T	synonymous_variant	0.89	pyrazinamide
clpC1	4038395	c.2310C>G	synonymous_variant	0.89	pyrazinamide
clpC1	4038398	c.2307G>T	synonymous_variant	0.89	pyrazinamide
clpC1	4038419	c.2286T>C	synonymous_variant	0.92	pyrazinamide
clpC1	4038434	c.2269_2271delGCGinsTA	frameshift_variant&missense_variant	0.89	pyrazinamide
clpC1	4038474	p.Ser744Ala	missense_variant	0.94	pyrazinamide
clpC1	4038485	p.Gly740Lys	missense_variant	0.94	pyrazinamide
clpC1	4038491	c.2214C>G	synonymous_variant	0.96	pyrazinamide
clpC1	4038499	p.Ser736Gly	missense_variant	0.98	pyrazinamide
clpC1	4038509	c.2196C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4038519	p.Arg729Glu	missense_variant	1.0	pyrazinamide
clpC1	4038530	c.2175G>A	synonymous_variant	1.0	pyrazinamide
clpC1	4038533	p.Arg724Lys	missense_variant	1.0	pyrazinamide
clpC1	4038539	c.2166G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038563	c.2142C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038575	c.2130C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038584	c.2121G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038596	c.2109A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038602	c.2103G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038620	p.Gln695Leu	missense_variant	0.99	pyrazinamide
clpC1	4038623	c.2082A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4038640	p.Asp689Asn	missense_variant	0.99	pyrazinamide
clpC1	4038647	c.2058T>G	synonymous_variant	0.99	pyrazinamide
clpC1	4038653	c.2052C>T	synonymous_variant	0.97	pyrazinamide
clpC1	4038658	p.Lys683Gln	missense_variant	0.97	pyrazinamide
clpC1	4038659	c.2044_2046delTCCinsAT	frameshift_variant&missense_variant	0.97	pyrazinamide
clpC1	4038662	c.2043T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038671	c.2034T>A	synonymous_variant	0.98	pyrazinamide
clpC1	4038679	p.Pro676Ala	missense_variant	0.98	pyrazinamide
clpC1	4038683	c.2022T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4038698	c.2007C>T	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4038704	c.2001T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038710	c.1995G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038713	c.1992T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038721	c.1984C>T	synonymous_variant	0.97	pyrazinamide
clpC1	4038726	p.Thr660Cys	missense_variant	0.98	pyrazinamide
clpC1	4038773	c.1932T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038782	c.1923G>T	synonymous_variant	0.98	pyrazinamide
clpC1	4038790	c.1915C>T	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4038809	p.Gln632Ala	missense_variant	0.94	pyrazinamide
clpC1	4038812	c.1893T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038815	c.1890G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4038838	c.1867C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4038875	c.1830C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038878	c.1827A>G	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4038881	c.1824C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4038890	c.1815G>A	synonymous_variant	0.96	pyrazinamide
clpC1	4038905	c.1800A>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038908	c.1797C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038911	c.1794G>T	synonymous_variant	0.97	pyrazinamide
clpC1	4038914	c.1791G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038917	c.1788C>T	synonymous_variant	0.97	pyrazinamide
clpC1	4038923	c.1782A>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038941	c.1764G>A	synonymous_variant	0.98	pyrazinamide
clpC1	4038953	c.1752A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4038956	c.1749T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038965	c.1740T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038971	c.1734T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038989	c.1716T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038997	c.1708T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4039001	c.1702_1704delAACinsGG	frameshift_variant&missense_variant	0.98	pyrazinamide
clpC1	4039022	c.1683A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039070	c.1635G>T	synonymous_variant	0.98	pyrazinamide
clpC1	4039073	c.1632C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039085	c.1620A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039090	c.1615C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4039097	c.1608G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039112	c.1593C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039119	c.1585_1586delTCinsAG	synonymous_variant	0.98	pyrazinamide
clpC1	4039121	c.1584T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039124	c.1581C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039133	c.1572C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039142	c.1563A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039145	c.1560G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039169	p.Glu512Asp	missense_variant	0.99	pyrazinamide
clpC1	4039183	c.1522T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039187	c.1518G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039243	c.1462C>T	synonymous_variant	0.99	pyrazinamide
clpC1	4039274	c.1431G>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4039277	c.1428C>T	synonymous_variant	0.97	pyrazinamide
clpC1	4039280	c.1425G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039292	c.1413C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039295	c.1410A>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039298	c.1407T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039313	c.1392C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039316	c.1389G>A	synonymous_variant	0.98	pyrazinamide
clpC1	4039319	c.1386T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4039322	c.1383T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039328	c.1377A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039334	c.1371G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039338	p.Thr456Gln	missense_variant	0.98	pyrazinamide
clpC1	4039349	c.1356C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4039352	c.1353C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039364	c.1341C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039382	c.1323C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039391	c.1314T>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039394	c.1311G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039397	c.1308A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039409	c.1296T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039412	c.1293T>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039415	p.Glu430Asp	missense_variant	0.99	pyrazinamide	Uncertain significance
clpC1	4039430	c.1275T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039439	c.1266C>T	synonymous_variant	0.99	pyrazinamide
clpC1	4039442	c.1263A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039454	c.1251A>G	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
clpC1	4039463	c.1242C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039466	c.1239T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039469	c.1236T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039472	c.1233G>A	synonymous_variant	0.98	pyrazinamide
clpC1	4039487	c.1218G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039517	c.1188C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039556	c.1149G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039559	c.1146C>A	synonymous_variant	0.98	pyrazinamide
clpC1	4039562	c.1143C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039568	p.Met379Ile	missense_variant	0.98	pyrazinamide	Uncertain significance
clpC1	4039576	p.Ala377Ser	missense_variant	0.98	pyrazinamide
clpC1	4039577	c.1128T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4039581	p.Thr375Ser	missense_variant	0.98	pyrazinamide
clpC1	4039589	c.1116G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039601	c.1104G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039610	c.1095G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039622	c.1083C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039649	c.1056G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039652	c.1053G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039655	c.1050G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039664	c.1041G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039682	c.1023C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039724	c.981A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039733	c.972G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039736	c.969C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039748	c.957G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039751	c.954A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039766	c.939T>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039769	c.936C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039778	c.927A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039781	c.924G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039793	c.912C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039814	c.891C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039817	c.888A>T	synonymous_variant	0.98	pyrazinamide
clpC1	4039820	c.885T>G	synonymous_variant	0.99	pyrazinamide
clpC1	4039826	c.879C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039831	c.874T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039840	c.865C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4039850	c.855T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039865	c.840T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039871	c.834C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4039898	c.807C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039904	c.801A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039925	c.780C>T	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039931	c.774T>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039934	c.771G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039946	c.759A>T	synonymous_variant	0.99	pyrazinamide
clpC1	4039952	c.753T>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039958	c.747G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4039991	c.714G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039997	c.708C>T	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4040001	p.His235Ala	missense_variant	0.98	pyrazinamide
clpC1	4040021	c.684A>T	synonymous_variant	0.98	pyrazinamide
clpC1	4040024	c.681A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4040030	c.675C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4040033	c.672G>T	synonymous_variant	0.98	pyrazinamide
clpC1	4040057	c.648C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4040090	c.613_615delTCTinsAGC	synonymous_variant	0.99	pyrazinamide
clpC1	4040093	c.610_612delCTCinsTG	frameshift_variant&synonymous_variant	0.98	pyrazinamide
clpC1	4040138	c.567G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4040144	c.561G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4040147	c.558A>G	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
clpC1	4040153	c.552A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4040159	c.546G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040162	c.543G>T	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4040168	c.537G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040171	c.534C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4040180	c.525C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4040192	c.513C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4040348	c.357G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4040351	c.354C>T	synonymous_variant	0.91	pyrazinamide
clpC1	4040354	c.351A>G	synonymous_variant	0.92	pyrazinamide
clpC1	4040363	c.342A>T	synonymous_variant	0.97	pyrazinamide
clpC1	4040369	c.336C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4040375	c.330G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4040380	c.325T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4040387	c.318A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4040393	c.312G>C	synonymous_variant	0.95	pyrazinamide	Not assoc w R - Interim
clpC1	4040402	c.303C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4040411	c.294T>C	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
clpC1	4040423	c.282A>G	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
clpC1	4040431	c.274T>C	synonymous_variant	0.99	pyrazinamide
clpC1	4040441	c.264C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4040444	c.261C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4040450	c.255A>G	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4040456	c.249C>T	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4040459	c.246C>A	synonymous_variant	0.98	pyrazinamide
clpC1	4040465	c.240T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4040471	c.234T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4040522	c.183T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4040531	c.174T>G	synonymous_variant	0.99	pyrazinamide
clpC1	4040539	c.166C>T	synonymous_variant	0.99	pyrazinamide
clpC1	4040540	c.165G>T	synonymous_variant	0.99	pyrazinamide
clpC1	4040546	c.159G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4040551	c.154T>C	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
clpC1	4040552	c.153G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4040561	c.144A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4040573	c.132T>A	synonymous_variant	0.99	pyrazinamide
clpC1	4040582	c.123G>T	synonymous_variant	0.96	pyrazinamide
clpC1	4040585	c.120A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4040588	c.117T>C	synonymous_variant	0.99	pyrazinamide
clpC1	4040600	c.103_105delTTAinsCG	frameshift_variant&missense_variant	0.99	pyrazinamide
clpC1	4040603	c.102T>G	synonymous_variant	0.99	pyrazinamide
clpC1	4040606	c.99T>C	synonymous_variant	0.98	pyrazinamide
clpC1	4040618	c.87C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4040644	c.61A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040654	c.51G>A	synonymous_variant	1.0	pyrazinamide
clpC1	4040657	c.48T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040669	c.36C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4040681	c.24T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040695	c.10C>A	synonymous_variant	0.96	pyrazinamide
clpC1	4040696	c.9A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040708	c.-4A>G	upstream_gene_variant	0.93	pyrazinamide
panD	4044072	c.210C>A	synonymous_variant	1.0	pyrazinamide
panD	4044075	c.207T>C	synonymous_variant	1.0	pyrazinamide
panD	4044078	c.204G>C	synonymous_variant	1.0	pyrazinamide
panD	4044084	c.198T>C	synonymous_variant	1.0	pyrazinamide
panD	4044090	c.192C>G	synonymous_variant	1.0	pyrazinamide
panD	4044093	c.189A>G	synonymous_variant	1.0	pyrazinamide
panD	4044105	c.177G>C	synonymous_variant	1.0	pyrazinamide
panD	4044120	c.162A>C	synonymous_variant	1.0	pyrazinamide
panD	4044123	c.159T>C	synonymous_variant	1.0	pyrazinamide
panD	4044126	c.156T>C	synonymous_variant	1.0	pyrazinamide
panD	4044138	c.144T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
panD	4044147	c.135C>G	synonymous_variant	1.0	pyrazinamide
panD	4044150	c.132A>C	synonymous_variant	1.0	pyrazinamide
panD	4044156	c.126A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
panD	4044159	c.123C>T	synonymous_variant	1.0	pyrazinamide
panD	4044162	c.120A>G	synonymous_variant	1.0	pyrazinamide
panD	4044165	c.117G>C	synonymous_variant	1.0	pyrazinamide
panD	4044174	c.108C>T	synonymous_variant	1.0	pyrazinamide
panD	4044177	c.105C>T	synonymous_variant	1.0	pyrazinamide
panD	4044188	c.94T>C	synonymous_variant	1.0	pyrazinamide
panD	4044189	c.93C>T	synonymous_variant	1.0	pyrazinamide
panD	4044195	c.87T>C	synonymous_variant	1.0	pyrazinamide
panD	4044216	c.66C>T	synonymous_variant	1.0	pyrazinamide
panD	4044228	c.54C>T	synonymous_variant	1.0	pyrazinamide
panD	4044231	p.Cys17His	missense_variant	1.0	pyrazinamide
panD	4044234	c.48C>T	synonymous_variant	1.0	pyrazinamide
panD	4044237	c.45G>C	synonymous_variant	1.0	pyrazinamide
panD	4044246	c.36C>T	synonymous_variant	1.0	pyrazinamide
panD	4044264	c.18G>C	synonymous_variant	1.0	pyrazinamide
panD	4044276	p.Leu2Phe	missense_variant	1.0	pyrazinamide
glpK	4138454	c.1302G>A	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138457	c.1299C>T	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138460	c.1296C>T	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138464	p.Gly431Ala	missense_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138472	c.1284G>T	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138478	c.1278T>C	synonymous_variant	0.88	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138481	c.1275G>C	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138490	c.1266G>T	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138494	p.Gln421Gly	missense_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138496	c.1260G>T	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138500	p.Arg419His	missense_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138502	c.1254T>G	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138511	c.1245C>T	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138514	c.1242A>C	synonymous_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138523	c.1233C>T	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138526	p.Asp410Glu	missense_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138529	p.Val409Ala	missense_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138550	c.1206C>T	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138568	c.1188A>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138571	c.1185C>G	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138574	c.1182G>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138580	c.1176C>T	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138589	c.1167C>T	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138598	c.1158G>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138601	c.1155G>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138606	c.1150T>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138610	c.1146C>G	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138615	p.Ile381Val	missense_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138622	c.1134C>T	synonymous_variant	0.99	ethambutol	Not assoc w R
					moxifloxacin	Not assoc w R
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R
					rifampicin	Not assoc w R
					isoniazid	Not assoc w R
glpK	4138631	c.1125C>G	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138634	c.1122G>T	synonymous_variant	0.99	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138643	c.1113A>G	synonymous_variant	0.99	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138654	c.1102C>T	synonymous_variant	0.98	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138658	c.1098C>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138661	c.1095T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138676	c.1080T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138682	c.1074C>G	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138696	p.Pro354Ser	missense_variant	0.96	ethambutol	Uncertain significance
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
glpK	4138703	c.1053C>G	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138712	p.Ala348Ser	missense_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138718	p.Ser346Val	missense_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138726	p.Ala344Thr	missense_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138751	c.1005T>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138757	c.997_999delCTAinsTG	frameshift_variant&synonymous_variant	0.98	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
glpK	4138772	c.984G>T	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138775	c.981C>T	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138781	c.975G>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138793	c.963T>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138796	c.960A>G	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138799	c.957T>G	synonymous_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138805	c.951C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
embC	4240702	c.840G>C	synonymous_variant	1.0	ethambutol
embC	4240708	c.846G>C	synonymous_variant	1.0	ethambutol
embC	4240717	c.855T>C	synonymous_variant	0.96	ethambutol
embC	4240726	c.864G>C	synonymous_variant	0.96	ethambutol	Not assoc w R - Interim
embC	4240736	c.874_875delTCinsAG	synonymous_variant	0.96	ethambutol
embC	4240765	c.903C>G	synonymous_variant	0.96	ethambutol
embC	4240769	c.907_909delGTGinsAC	frameshift_variant&missense_variant	0.96	ethambutol
embC	4240783	c.921G>C	synonymous_variant	0.96	ethambutol
embC	4240789	c.927T>C	synonymous_variant	0.96	ethambutol
embC	4240800	p.Tyr313Phe	missense_variant	0.96	ethambutol
embC	4240819	c.957A>C	synonymous_variant	0.95	ethambutol
embC	4240831	c.969T>G	synonymous_variant	0.95	ethambutol
embC	4240855	c.993G>C	synonymous_variant	0.89	ethambutol
embC	4240859	p.Leu333Val	missense_variant	0.88	ethambutol
embC	4240912	c.1050G>C	synonymous_variant	0.9	ethambutol
embC	4240921	c.1059C>G	synonymous_variant	0.87	ethambutol
embC	4240922	p.Thr354Ala	missense_variant	0.87	ethambutol
embC	4240934	c.1072_1074delGTAinsCG	frameshift_variant&missense_variant	0.9	ethambutol
embC	4240945	c.1083T>A	synonymous_variant	0.91	ethambutol
embC	4240951	c.1089C>G	synonymous_variant	0.91	ethambutol
embC	4240954	c.1092T>C	synonymous_variant	0.9	ethambutol
embC	4240966	c.1104G>C	synonymous_variant	0.95	ethambutol
embC	4240978	c.1116G>A	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embC	4240979	p.Thr373His	missense_variant	0.94	ethambutol
embC	4240990	c.1128A>G	synonymous_variant	0.96	ethambutol
embC	4240996	c.1134G>C	synonymous_variant	0.95	ethambutol
embC	4241002	c.1140G>C	synonymous_variant	0.98	ethambutol
embC	4241008	c.1146G>C	synonymous_variant	0.98	ethambutol
embC	4241017	c.1155T>C	synonymous_variant	0.98	ethambutol
embC	4241023	c.1161T>G	synonymous_variant	0.98	ethambutol
embC	4241024	p.Val388Phe	missense_variant	0.98	ethambutol
embC	4241030	c.1168C>T	synonymous_variant	0.98	ethambutol
embC	4241039	p.Asp393Asn	missense_variant	0.98	ethambutol
embC	4241047	c.1185C>G	synonymous_variant	0.98	ethambutol
embC	4241050	c.1188T>G	synonymous_variant	0.98	ethambutol
embC	4241053	c.1191G>T	synonymous_variant	0.98	ethambutol
embC	4241071	c.1209C>G	synonymous_variant	0.99	ethambutol
embC	4241084	p.Leu408Ala	missense_variant	0.99	ethambutol
embC	4241135	p.Val425Leu	missense_variant	0.99	ethambutol
embC	4241140	c.1278A>G	synonymous_variant	0.99	ethambutol	Not assoc w R - Interim
embC	4241158	c.1296T>C	synonymous_variant	0.99	ethambutol
embC	4241161	c.1299C>G	synonymous_variant	0.99	ethambutol	Not assoc w R - Interim
embC	4241162	p.Leu434Met	missense_variant	0.99	ethambutol
embC	4241167	c.1305C>G	synonymous_variant	0.99	ethambutol
embC	4241168	c.1306C>T	synonymous_variant	0.99	ethambutol	Not assoc w R - Interim
embC	4241185	c.1323G>C	synonymous_variant	0.98	ethambutol
embC	4241188	c.1326C>G	synonymous_variant	0.99	ethambutol
embC	4241194	c.1332C>G	synonymous_variant	0.99	ethambutol
embC	4241215	c.1353C>G	synonymous_variant	0.97	ethambutol
embC	4241224	c.1362G>T	synonymous_variant	0.98	ethambutol
embC	4241230	c.1368A>G	synonymous_variant	0.98	ethambutol
embC	4241233	c.1371G>C	synonymous_variant	0.97	ethambutol
embC	4241240	c.1378C>T	synonymous_variant	0.97	ethambutol
embC	4241251	c.1389T>C	synonymous_variant	0.94	ethambutol
embC	4241256	p.Arg465Lys	missense_variant	0.93	ethambutol
embC	4241259	p.Arg466Gln	missense_variant	0.92	ethambutol	Uncertain significance
embA	4244669	c.1437G>C	synonymous_variant	0.92	ethambutol
embA	4244681	c.1449A>C	synonymous_variant	0.95	ethambutol
embA	4244694	p.Lys488Val	missense_variant	0.91	ethambutol
embA	4244702	c.1470C>T	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
embA	4244726	p.Asp498Glu	missense_variant	0.96	ethambutol
embA	4244735	c.1503C>G	synonymous_variant	0.96	ethambutol
embA	4244747	c.1515T>G	synonymous_variant	0.95	ethambutol
embA	4244765	c.1533T>C	synonymous_variant	0.95	ethambutol
embA	4244768	p.Glu512Asp	missense_variant	0.95	ethambutol
embA	4244770	p.Gly513Ala	missense_variant	0.95	ethambutol
embA	4244775	p.Met515Leu	missense_variant	0.95	ethambutol
embA	4244778	p.Ser516Thr	missense_variant	0.95	ethambutol
embA	4244792	c.1560G>C	synonymous_variant	0.97	ethambutol
embA	4244802	c.1570T>C	synonymous_variant	0.98	ethambutol
embA	4244814	p.Leu528Met	missense_variant	0.98	ethambutol
embA	4244821	p.Gly530Ala	missense_variant	0.96	ethambutol
embA	4244823	p.Val531Met	missense_variant	0.94	ethambutol
embA	4244829	c.1597_1599delTTCinsGG	frameshift_variant&missense_variant	0.97	ethambutol	Uncertain significance
embA	4244853	c.1621_1623delGTGinsAC	frameshift_variant&missense_variant	0.97	ethambutol	Uncertain significance
embA	4244856	p.Ala542Asn	missense_variant	0.97	ethambutol
embA	4244862	p.Leu544Val	missense_variant	0.98	ethambutol
embA	4244885	c.1653A>G	synonymous_variant	0.97	ethambutol
embA	4244894	c.1662C>A	synonymous_variant	0.96	ethambutol
embA	4244895	c.1663_1665delACTinsTC	frameshift_variant&missense_variant	0.97	ethambutol	Uncertain significance
embA	4244900	c.1668G>C	synonymous_variant	0.97	ethambutol
embA	4244906	c.1674C>G	synonymous_variant	0.97	ethambutol
embA	4244919	c.1687_1689delCTCinsTG	frameshift_variant&missense_variant	0.96	ethambutol	Uncertain significance
embA	4244930	c.1698G>C	synonymous_variant	0.95	ethambutol
embA	4244933	c.1701A>G	synonymous_variant	0.95	ethambutol
embA	4244945	c.1713C>G	synonymous_variant	0.93	ethambutol
embA	4244959	p.Ala576Gly	missense_variant	0.91	ethambutol
embA	4244980	p.Val583Ala	missense_variant	0.9	ethambutol
embA	4244982	c.1750T>C	synonymous_variant	0.89	ethambutol
embA	4244986	p.Gly585Ala	missense_variant	0.89	ethambutol
embA	4244991	p.Val587Leu	missense_variant	0.89	ethambutol
embA	4245008	c.1776T>C	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
embA	4245015	p.Ile595Val	missense_variant	0.89	ethambutol	Uncertain significance
embA	4245020	c.1788T>G	synonymous_variant	0.87	ethambutol
embA	4245023	c.1791A>G	synonymous_variant	0.87	ethambutol	Not assoc w R - Interim
embA	4245026	c.1794T>C	synonymous_variant	0.87	ethambutol
embA	4245029	c.1797T>C	synonymous_variant	0.84	ethambutol
embA	4245039	c.1807_1809delCTCinsAG	frameshift_variant&missense_variant	0.84	ethambutol	Uncertain significance
embA	4245044	c.1812G>C	synonymous_variant	0.84	ethambutol
embA	4245050	c.1818C>T	synonymous_variant	0.82	ethambutol
embA	4245059	c.1827G>A	synonymous_variant	0.73	ethambutol
embA	4245060	c.1828T>C	synonymous_variant	0.73	ethambutol
embA	4245069	p.Val613Leu	missense_variant	0.71	ethambutol
embB	4247365	c.852A>C	synonymous_variant	0.6	ethambutol
embB	4247371	c.858C>A	synonymous_variant	0.84	ethambutol
embB	4247384	c.871_873delCATinsTC	frameshift_variant&missense_variant	0.92	ethambutol
embB	4247389	c.876C>G	synonymous_variant	0.92	ethambutol
embB	4247395	c.882C>G	synonymous_variant	0.9	ethambutol
embB	4247401	c.888T>C	synonymous_variant	0.9	ethambutol
embB	4247404	c.891G>C	synonymous_variant	0.91	ethambutol
embB	4247407	c.894G>C	synonymous_variant	0.91	ethambutol
embB	4247428	c.915C>G	synonymous_variant	0.91	ethambutol
embB	4247437	c.924A>G	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
embB	4247446	c.933C>T	synonymous_variant	0.92	ethambutol
embB	4247462	c.949_950delTCinsAG	synonymous_variant	0.95	ethambutol
embB	4247470	c.957T>C	synonymous_variant	0.96	ethambutol
embB	4247491	c.978G>C	synonymous_variant	0.99	ethambutol
embB	4247494	c.981G>A	synonymous_variant	0.99	ethambutol
embB	4247497	c.984T>C	synonymous_variant	0.99	ethambutol
embB	4247500	c.987C>G	synonymous_variant	0.99	ethambutol
embB	4247512	c.999T>C	synonymous_variant	0.99	ethambutol
embB	4247536	c.1023C>G	synonymous_variant	0.98	ethambutol
embB	4247539	c.1026T>C	synonymous_variant	0.98	ethambutol
embB	4247543	c.1030_1031delAGinsTC	synonymous_variant	0.99	ethambutol
embB	4247554	c.1041T>C	synonymous_variant	0.99	ethambutol
embB	4247555	c.1042_1044delCTGinsAC	frameshift_variant&missense_variant	0.99	ethambutol
embB	4247563	p.Met350Ile	missense_variant	0.99	ethambutol
embB	4247566	c.1053C>G	synonymous_variant	0.99	ethambutol
embB	4247572	c.1059A>G	synonymous_variant	0.99	ethambutol
embB	4247587	c.1074G>T	synonymous_variant	0.99	ethambutol
embB	4247590	c.1077A>G	synonymous_variant	0.99	ethambutol	Not assoc w R - Interim
embB	4247609	c.1096_1098delTCGinsAGC	synonymous_variant	0.98	ethambutol
embB	4247629	c.1116C>G	synonymous_variant	0.97	ethambutol
embB	4247630	p.Leu373Phe	missense_variant	0.97	ethambutol
embB	4247635	c.1122G>C	synonymous_variant	0.97	ethambutol
embB	4247638	c.1125G>C	synonymous_variant	0.97	ethambutol
embB	4247646	p.Glu378Ala	missense_variant	0.93	ethambutol	Not assoc w R
embB	4247656	c.1143A>G	synonymous_variant	0.86	ethambutol
embB	4247857	c.1344C>G	synonymous_variant	0.58	ethambutol
embB	4247866	c.1353G>A	synonymous_variant	0.76	ethambutol
embB	4247879	p.Val456Leu	missense_variant	0.81	ethambutol
embB	4247893	c.1380C>T	synonymous_variant	0.81	ethambutol
embB	4247897	p.Met462Leu	missense_variant	0.81	ethambutol
embB	4247908	c.1395C>T	synonymous_variant	0.82	ethambutol
embB	4247909	c.1396T>C	synonymous_variant	0.82	ethambutol
embB	4247923	c.1410T>C	synonymous_variant	0.86	ethambutol
embB	4247927	c.1414_1416delCTGinsAT	frameshift_variant&missense_variant	0.86	ethambutol
embB	4247930	p.Val473His	missense_variant	0.82	ethambutol
embB	4247938	c.1425G>C	synonymous_variant	0.83	ethambutol
embB	4247940	p.Leu476Trp	missense_variant	0.83	ethambutol
embB	4247945	c.1432T>C	synonymous_variant	0.89	ethambutol
embB	4247951	p.Ser480Ala	missense_variant	0.9	ethambutol
embB	4247957	c.1444_1446delATGinsCA	frameshift_variant&missense_variant	0.91	ethambutol
embB	4247972	c.1459_1461delACCinsGG	frameshift_variant&missense_variant	0.95	ethambutol
embB	4247977	c.1464C>G	synonymous_variant	0.96	ethambutol
embB	4247996	p.Ala495Ser	missense_variant	0.96	ethambutol
embB	4248037	c.1524T>C	synonymous_variant	0.93	ethambutol
embB	4248041	p.Ala510Thr	missense_variant	0.93	ethambutol	Uncertain significance
embB	4248044	p.Lys511Ala	missense_variant	0.93	ethambutol
embB	4248052	c.1539G>C	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embB	4248055	c.1542G>C	synonymous_variant	0.94	ethambutol
embB	4248064	c.1551G>C	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
embB	4248070	c.1557T>C	synonymous_variant	0.95	ethambutol
embB	4248085	c.1572T>C	synonymous_variant	0.97	ethambutol
embB	4248097	c.1584C>G	synonymous_variant	0.98	ethambutol
embB	4248106	c.1593C>G	synonymous_variant	0.98	ethambutol
embB	4248118	c.1605T>C	synonymous_variant	0.97	ethambutol
embB	4248121	c.1608G>A	synonymous_variant	0.97	ethambutol
embB	4248133	c.1620C>G	synonymous_variant	0.96	ethambutol
embB	4248139	c.1626C>T	synonymous_variant	0.96	ethambutol
embB	4248142	c.1629T>C	synonymous_variant	0.96	ethambutol
embB	4248143	c.1630T>C	synonymous_variant	0.95	ethambutol
embB	4248149	p.Thr546Cys	missense_variant	0.95	ethambutol
embB	4248157	c.1644A>G	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
embB	4248173	p.Val554Met	missense_variant	0.95	ethambutol
embB	4248199	c.1686A>T	synonymous_variant	0.97	ethambutol
embB	4248200	p.Ile563Val	missense_variant	0.97	ethambutol
embB	4248206	p.Ser565Gly	missense_variant	0.97	ethambutol	Uncertain significance
embB	4248211	c.1698G>C	synonymous_variant	0.96	ethambutol
embB	4248215	p.Arg568Ser	missense_variant	0.95	ethambutol
embB	4248225	p.Ala571Val	missense_variant	0.94	ethambutol	Uncertain significance
embB	4248248	c.1735_1737delTTCinsCG	frameshift_variant&missense_variant	0.9	ethambutol
embB	4248252	p.Gly580Ala	missense_variant	0.9	ethambutol
embB	4248264	p.Phe584Ser	missense_variant	0.9	ethambutol
embB	4248275	p.Thr588Ala	missense_variant	0.91	ethambutol
embB	4248316	c.1803C>G	synonymous_variant	0.79	ethambutol
embB	4248318	c.1806_1807delAG	frameshift_variant	0.75	ethambutol
embB	4248323	p.Ala604Pro	missense_variant	0.75	ethambutol
embB	4248325	c.1813_1814insAG	frameshift_variant	0.75	ethambutol
embB	4248334	c.1821C>G	synonymous_variant	0.75	ethambutol
embB	4248343	c.1830G>C	synonymous_variant	0.75	ethambutol
embB	4248457	c.1944T>C	synonymous_variant	0.89	ethambutol
embB	4248460	c.1947C>G	synonymous_variant	0.89	ethambutol
embB	4248463	c.1950C>G	synonymous_variant	0.89	ethambutol
embB	4248469	c.1956C>T	synonymous_variant	0.89	ethambutol
embB	4248472	c.1959T>C	synonymous_variant	0.89	ethambutol
embB	4248485	p.Ser658Ala	missense_variant	0.88	ethambutol
embB	4248489	p.Ala659Asp	missense_variant	0.88	ethambutol
embB	4248497	p.Lys662Arg	missense_variant	0.88	ethambutol
embB	4248504	p.Asp664Gly	missense_variant	0.88	ethambutol	Uncertain significance
embB	4248514	c.2001A>C	synonymous_variant	0.88	ethambutol
embB	4248527	c.2014_2016delTTTinsCG	frameshift_variant&missense_variant	0.88	ethambutol
embB	4248541	c.2028T>C	synonymous_variant	0.94	ethambutol
embB	4248544	c.2031G>C	synonymous_variant	0.94	ethambutol
embB	4248545	p.Ile678Val	missense_variant	0.94	ethambutol
embB	4248550	c.2037C>G	synonymous_variant	0.94	ethambutol
embB	4248556	c.2043C>T	synonymous_variant	0.94	ethambutol
embB	4248558	p.Tyr682Trp	missense_variant	0.94	ethambutol
embB	4248565	c.2052C>G	synonymous_variant	0.94	ethambutol