Run ID: SRR11662690
Sample name:
Date: 2024-04-15T05:14:27.630287
Number of reads: 2284545
Percentage reads mapped: 21.74
Median coverage: 5.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 1.0 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.82 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | kasA | p.Arg121Lys | Mutation from literature | |
| ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | gyrB | p.Thr500Asn | Uncertain significance | Mutation from literature |
| ofloxacin | ||||
| levofloxacin | gyrB | p.Thr500Asn | Uncertain significance | Mutation from literature |
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | pepQ | c.604_606delATCinsGG | Assoc w R - Interim | |
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.634_636delCGAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| fbiC | c.550_552delCAAinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.682_684delCTCinsAG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2026_2028delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2344_2346delTCGinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | pepQ | c.604_606delATCinsGG | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV |
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| gyrB | 6738 | p.Thr500Asn | missense_variant | 0.99 | moxifloxacin | Uncertain significance | Mutation from literature |
| levofloxacin | Uncertain significance | Mutation from literature | |||||
| fgd1 | 491416 | c.634_636delCGAinsTG | frameshift_variant&stop_gained | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303480 | c.550_552delCAAinsGG | frameshift_variant&missense_variant | 0.97 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303612 | c.682_684delCTCinsAG | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1304956 | c.2026_2028delGTTinsAC | frameshift_variant&missense_variant | 0.97 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305274 | c.2344_2346delTCGinsCC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance | Mutation from literature |
| kasA | 2518476 | p.Arg121Lys | missense_variant | 0.98 | isoniazid | Mutation from literature | |
| pepQ | 2859813 | c.604_606delATCinsGG | frameshift_variant&missense_variant | 0.98 | clofazimine | Assoc w R - Interim | |
| bedaquiline | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV | |||||
| embB | 4247580 | p.Ala356Val | missense_variant | 0.95 | ethambutol | Uncertain significance | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 654 | c.654A>G | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 663 | c.663A>C | synonymous_variant | 0.94 | isoniazid | |
| dnaA | 672 | c.672T>C | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
| dnaA | 673 | p.Ala225Thr | missense_variant | 0.93 | isoniazid | Uncertain significance |
| dnaA | 678 | c.678A>G | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
| dnaA | 682 | c.682_684delTTGinsCC | frameshift_variant&missense_variant | 0.93 | isoniazid | Uncertain significance |
| dnaA | 690 | c.690G>C | synonymous_variant | 0.84 | isoniazid | |
| dnaA | 693 | c.693A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 699 | c.699G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 705 | c.705A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 720 | c.720G>A | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 723 | c.723A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 741 | c.741T>C | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 0.98 | isoniazid | |
| dnaA | 771 | c.771A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 793 | c.793_795delGTAinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 798 | c.798C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 801 | c.801G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 805 | c.805T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 864 | c.864C>T | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 876 | c.876C>G | synonymous_variant | 0.96 | isoniazid | |
| dnaA | 877 | c.877T>C | synonymous_variant | 0.96 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 897 | c.897A>G | synonymous_variant | 0.89 | isoniazid | |
| dnaA | 903 | c.903C>G | synonymous_variant | 0.84 | isoniazid | Not assoc w R - Interim |
| dnaA | 1014 | c.1014C>G | synonymous_variant | 0.83 | isoniazid | |
| dnaA | 1020 | c.1020C>G | synonymous_variant | 0.83 | isoniazid | |
| dnaA | 1023 | c.1023C>T | synonymous_variant | 0.83 | isoniazid | |
| dnaA | 1024 | c.1024T>C | synonymous_variant | 0.83 | isoniazid | |
| dnaA | 1035 | c.1035A>G | synonymous_variant | 0.85 | isoniazid | |
| dnaA | 1038 | c.1038A>G | synonymous_variant | 0.92 | isoniazid | |
| dnaA | 1050 | c.1050G>C | synonymous_variant | 0.93 | isoniazid | |
| dnaA | 1055 | p.Ala352Asp | missense_variant | 0.87 | isoniazid | |
| dnaA | 1059 | c.1059C>G | synonymous_variant | 0.87 | isoniazid | |
| dnaA | 1064 | p.Asp355Gly | missense_variant | 0.88 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 0.89 | isoniazid | |
| dnaA | 1071 | c.1071C>G | synonymous_variant | 0.91 | isoniazid | |
| dnaA | 1077 | c.1077A>G | synonymous_variant | 0.93 | isoniazid | |
| dnaA | 1080 | c.1080C>G | synonymous_variant | 0.94 | isoniazid | |
| dnaA | 1088 | p.Ser363Thr | missense_variant | 0.93 | isoniazid | Uncertain significance |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
| dnaA | 1098 | c.1098A>G | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1110 | c.1110T>C | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1140 | c.1140C>G | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1149 | c.1149C>G | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
| dnaA | 1152 | c.1152A>G | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1153 | c.1153_1155delTTGinsCC | frameshift_variant&missense_variant | 0.97 | isoniazid | Uncertain significance |
| dnaA | 1164 | c.1164A>C | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1167 | c.1167A>G | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
| dnaA | 1174 | p.Lys392Arg | missense_variant | 0.97 | isoniazid | |
| dnaA | 1191 | c.1191T>C | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1194 | c.1194G>C | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1197 | c.1197T>G | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1203 | c.1203T>C | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1220 | p.Asn407Ser | missense_variant | 0.98 | isoniazid | |
| dnaA | 1230 | c.1230A>G | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 1239 | c.1239G>C | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 1244 | p.Thr415Ile | missense_variant | 0.93 | isoniazid | |
| gyrB | 6115 | c.876A>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6123 | p.Ala295Gly | missense_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6170 | p.His311Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6203 | c.964_966delAGCinsTCG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6215 | c.976_978delTCGinsAGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6238 | c.999G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6242 | p.Arg335Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6253 | c.1014G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6283 | p.Asp348Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6298 | c.1059C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6304 | c.-998C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6307 | c.-995T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6324 | c.1085_1086insGTCC | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 6327 | c.1090_1093delGAAC | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6334 | c.-968G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6361 | c.-941G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6379 | c.-923C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6385 | c.-917G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6403 | c.-899T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6550 | c.1311A>G | synonymous_variant | 0.76 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6571 | c.-731T>C | upstream_gene_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6577 | c.1338T>C | synonymous_variant | 0.87 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6580 | c.-722C>G | upstream_gene_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6582 | p.Thr448Asn | missense_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6586 | c.-716T>C | upstream_gene_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6589 | c.-713G>C | upstream_gene_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6590 | p.Arg451Ser | missense_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6597 | p.Ser453Cys | missense_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6619 | c.-683T>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6625 | c.-677G>A | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>T | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6715 | c.1476C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6778 | c.-524C>T | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6798 | p.Gly520Ala | missense_variant | 0.99 | levofloxacin | Not assoc w R |
| moxifloxacin | Uncertain significance | |||||
| gyrB | 6811 | c.1572C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6869 | c.-433T>C | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6872 | c.-430T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6889 | c.-413G>T | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6902 | c.1663_1665delCTCinsTG | frameshift_variant&missense_variant | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 6911 | p.Asn558His | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6916 | c.-386G>A | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6919 | c.1680T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6922 | c.1683G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6926 | c.1687T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6931 | c.-371A>T | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6965 | p.Ser576Gly | missense_variant | 0.98 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrB | 6967 | c.1728_1729insTCG | conservative_inframe_insertion | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6976 | c.-326A>G | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6994 | c.-308C>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6997 | c.-305G>A | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>A | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7039 | c.-263G>A | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7047 | p.Lys603Met | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7114 | c.-188C>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7153 | c.1914G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7168 | c.-134C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7210 | p.Asp657Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7222 | c.1983C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7225 | c.-77T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7237 | c.-65C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7243 | c.-59G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7299 | c.-3T>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7313 | c.12G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7317 | c.16T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7322 | c.21G>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7325 | c.24delTinsCGGA | conservative_inframe_insertion&synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7337 | c.36C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7340 | p.Asp13Glu | missense_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7349 | c.48A>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7412 | c.111C>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7517 | c.216G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7529 | c.228G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7613 | c.312G>A | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7619 | c.318C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7673 | c.372G>A | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382A>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCT | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7745 | c.444G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7760 | c.459C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7775 | c.474C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7859 | c.558A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7874 | c.573G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7886 | c.585T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7890 | c.589C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7898 | p.Asp199Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7911 | p.Ala204Cys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7919 | p.Glu206Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7922 | c.621T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7923 | p.His208Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7942 | p.Glu214Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7951 | p.Ala217Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7958 | c.657C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7963 | p.Gly221Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7970 | c.669T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7973 | c.672A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7988 | c.687G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8247 | p.Ile316Val | missense_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8258 | c.957G>A | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8378 | c.1077C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8401 | p.Asp367Ala | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8408 | c.1107A>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8426 | c.1125G>A | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8432 | c.1131C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8465 | c.1164C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8472 | c.1171C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8492 | c.1191G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8501 | c.1200G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8529 | p.Ala410Arg | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8585 | c.1284C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8591 | c.1290C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8597 | c.1296C>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8600 | c.1299G>A | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8606 | c.1305C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8627 | c.1326C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8649 | p.Arg450Lys | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8717 | c.1416C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8731 | p.Gly477Ala | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8744 | p.Asp481Glu | missense_variant | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8761 | p.Val487Ala | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8769 | p.His490Tyr | missense_variant | 0.98 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8786 | c.1485T>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8813 | p.Asp504Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8864 | c.1563C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8942 | c.1641G>T | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9017 | c.1716C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9064 | p.Ser588Leu | missense_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9074 | c.1773G>A | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9092 | c.1791C>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9144 | p.Arg615Lys | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9147 | p.Gly616Ser | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9153 | p.Thr618Glu | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9161 | c.1860C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9167 | c.1866C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9227 | c.1926C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9248 | c.1947G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9308 | c.2007C>T | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9398 | c.2097T>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9401 | c.2100G>T | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9413 | c.2112G>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9419 | c.2118T>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9420 | p.Ile707Ala | missense_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9435 | c.2134C>T | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9440 | c.2139G>A | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9443 | c.2142G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9449 | c.2148C>G | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9452 | c.2151G>C | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9455 | c.2154T>G | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9458 | c.2157A>G | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9459 | p.Gly720Asn | missense_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491151 | c.369G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491184 | c.402A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491206 | c.424C>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491220 | c.438C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491223 | c.441C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491226 | c.444C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491229 | c.447C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491249 | p.Arg156Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491256 | c.474G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491307 | c.525C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491316 | c.534C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491340 | c.558C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491343 | c.561C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491367 | c.585G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491379 | c.597C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491382 | c.600G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491412 | c.630G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491428 | p.Ala216Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491436 | c.654T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491439 | p.Asp219Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491442 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491443 | p.Ser221Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491447 | p.Val222Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491472 | c.690A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491493 | c.711C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491499 | c.717G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491546 | p.Thr255Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491563 | c.781_782delAGinsTC | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491571 | c.789C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491595 | c.813C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491643 | c.861G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491646 | c.864G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491649 | c.867C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491661 | c.879C>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491664 | c.882C>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491673 | c.891A>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491676 | c.894T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491679 | c.897A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491688 | c.906A>G | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491694 | c.912C>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491709 | c.927A>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491712 | c.930T>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575665 | c.318G>T | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575701 | c.354G>A | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575714 | p.Tyr123Asn | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 0.98 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575770 | c.423G>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575772 | p.Val142Ala | missense_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575776 | c.429C>T | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575795 | c.448_450delATCinsGG | frameshift_variant&missense_variant | 0.99 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575803 | c.456C>T | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575818 | c.471G>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575840 | c.494dupC | frameshift_variant | 0.98 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575844 | c.498delC | frameshift_variant | 0.98 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575848 | c.501C>T | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575851 | c.504C>G | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| mshA | 575892 | p.Ala182Gly | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575899 | c.552G>A | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575905 | c.558G>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575908 | c.561A>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575916 | p.Asp190Ala | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575924 | p.Gly193Thr | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575932 | c.585G>A | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575953 | c.606G>C | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575956 | c.609G>A | synonymous_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| mshA | 575980 | c.633T>C | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575984 | c.637T>C | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 576004 | c.657T>C | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 576345 | p.His333Arg | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576347 | p.Thr334Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576352 | p.Asp335Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576362 | c.1015T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576367 | c.1020T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576376 | c.1029G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576379 | c.1032C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576380 | c.1033C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576385 | c.1038T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576406 | c.1059G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576418 | c.1071G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576421 | c.1074T>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576425 | p.Val360Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576433 | c.1086C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576436 | c.1089A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576439 | c.1092G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576445 | c.1098C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576448 | c.1101A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576457 | c.1110G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576466 | c.1119G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576469 | c.1122G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576481 | c.1134C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576484 | c.1137C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619648 | c.-243C>G | upstream_gene_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619657 | c.-234C>G | upstream_gene_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619669 | c.-222G>C | upstream_gene_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619672 | c.-219A>C | upstream_gene_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619676 | c.-215C>G | upstream_gene_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619681 | c.-210G>C | upstream_gene_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619684 | c.-207G>C | upstream_gene_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619687 | c.-204G>T | upstream_gene_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619688 | c.-203C>G | upstream_gene_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619697 | c.-194A>C | upstream_gene_variant | 0.79 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619708 | c.-183G>C | upstream_gene_variant | 0.71 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619712 | c.-179_-177delGCGinsATC | upstream_gene_variant | 0.77 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619725 | c.-165_-164delGA | upstream_gene_variant | 0.77 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619729 | c.-161delA | upstream_gene_variant | 0.77 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619735 | c.-156G>C | upstream_gene_variant | 0.77 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619744 | c.-147A>G | upstream_gene_variant | 0.77 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619762 | c.-129C>G | upstream_gene_variant | 0.83 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619766 | c.-125A>G | upstream_gene_variant | 0.83 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620247 | p.Leu119Phe | missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620257 | c.367_369delATCinsGG | frameshift_variant&missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620264 | p.Gly125Ala | missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620273 | p.Val128Ala | missense_variant | 0.9 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620275 | c.385C>T | synonymous_variant | 0.9 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | p.Ala132Pro | missense_variant | 0.9 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 0.9 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620290 | p.Tyr134His | missense_variant | 0.9 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| ccsA | 620307 | c.417C>G | synonymous_variant | 0.9 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620311 | p.Leu141Val | missense_variant | 0.9 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620335 | c.445_447delCTCinsTG | frameshift_variant&missense_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620343 | c.453G>C | synonymous_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620349 | c.459A>G | synonymous_variant | 0.93 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>A | synonymous_variant | 0.71 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 0.81 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620406 | c.516G>A | synonymous_variant | 0.81 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620409 | c.519C>G | synonymous_variant | 0.81 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 0.81 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 0.81 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620431 | p.Leu181Ile | missense_variant | 0.79 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620436 | c.546T>C | synonymous_variant | 0.79 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620439 | c.549T>G | synonymous_variant | 0.79 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 0.79 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620454 | c.564C>G | synonymous_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620460 | c.570T>C | synonymous_variant | 0.83 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620463 | c.573C>G | synonymous_variant | 0.83 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620569 | c.679_681delGGAinsCC | frameshift_variant&missense_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620577 | c.687C>G | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620580 | c.690C>T | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620586 | c.696C>G | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620592 | c.702C>T | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620598 | c.708C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620601 | c.711C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620607 | c.717T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620619 | c.729G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620631 | c.741T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620634 | c.744C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620648 | p.Glu253Gly | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620670 | c.780C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620703 | c.813G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| Rv0565c | 656292 | c.1179G>C | synonymous_variant | 0.94 | ethionamide | |
| Rv0565c | 656298 | c.1173G>C | synonymous_variant | 0.94 | ethionamide | |
| Rv0565c | 656310 | c.1161T>C | synonymous_variant | 0.95 | ethionamide | |
| Rv0565c | 656332 | p.Asp380Gly | missense_variant | 0.98 | ethionamide | Uncertain significance |
| Rv0565c | 656358 | c.1113T>C | synonymous_variant | 0.97 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656364 | c.1107T>C | synonymous_variant | 0.97 | ethionamide | |
| Rv0565c | 656366 | c.1100_1104delCTCGG | frameshift_variant | 0.97 | ethionamide | Uncertain significance |
| Rv0565c | 656375 | c.1095_1096insAAGCC | frameshift_variant | 0.97 | ethionamide | Uncertain significance |
| Rv0565c | 656383 | p.Val363Asn | missense_variant | 0.97 | ethionamide | |
| Rv0565c | 656391 | c.1080C>G | synonymous_variant | 0.97 | ethionamide | |
| Rv0565c | 656401 | p.Ala357Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656403 | c.1068C>G | synonymous_variant | 0.97 | ethionamide | |
| Rv0565c | 656412 | c.1059T>C | synonymous_variant | 0.97 | ethionamide | |
| Rv0565c | 656415 | c.1056G>A | synonymous_variant | 0.97 | ethionamide | |
| Rv0565c | 656423 | c.1048T>C | synonymous_variant | 0.97 | ethionamide | |
| Rv0565c | 656442 | c.1029C>G | synonymous_variant | 0.96 | ethionamide | |
| Rv0565c | 656448 | c.1023T>C | synonymous_variant | 0.96 | ethionamide | |
| Rv0565c | 656454 | c.1017G>C | synonymous_variant | 0.96 | ethionamide | |
| Rv0565c | 656460 | c.1011C>G | synonymous_variant | 0.94 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.93 | ethionamide | |
| Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.98 | ethionamide | |
| Rv0565c | 657708 | c.-238C>A | upstream_gene_variant | 0.98 | ethionamide | |
| Rv0565c | 657724 | c.-254A>C | upstream_gene_variant | 0.98 | ethionamide | |
| Rv0565c | 657730 | c.-260A>G | upstream_gene_variant | 0.98 | ethionamide | |
| Rv0565c | 657732 | c.-263_-262delAGinsGA | upstream_gene_variant | 0.98 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.98 | ethionamide | |
| hadA | 731723 | c.-207T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731729 | c.-201C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731753 | c.-177A>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731756 | c.-174C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731792 | c.-138G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731810 | c.-120G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731840 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731843 | c.-87T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731852 | c.-78A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731859 | c.-71G>T | upstream_gene_variant | 1.0 | isoniazid | |
| nusG | 734384 | p.Ser44Thr | missense_variant | 1.0 | rifampicin | |
| nusG | 734391 | c.138C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| nusG | 734397 | c.144C>T | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.98 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734424 | c.171G>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734472 | c.219T>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734566 | c.313C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734571 | c.318C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| nusG | 734595 | c.342C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| nusG | 734596 | c.343T>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734614 | c.361_363delGCCinsTG | frameshift_variant&missense_variant | 0.98 | rifampicin | |
| nusG | 734625 | c.372T>C | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734631 | c.378G>C | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734634 | c.381G>C | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734637 | c.384G>C | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734643 | c.390G>C | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734778 | c.525G>T | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734781 | c.528A>G | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734787 | c.534T>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734794 | p.Val181Ile | missense_variant | 0.98 | rifampicin | Uncertain significance |
| nusG | 734814 | c.561G>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734820 | c.567A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| nusG | 734826 | c.573A>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734841 | c.588G>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734859 | c.606G>C | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734863 | p.Thr204Ser | missense_variant | 0.99 | rifampicin | |
| nusG | 734889 | c.636G>A | synonymous_variant | 0.99 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734928 | c.675A>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734931 | c.678A>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734934 | c.681G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| nusG | 734940 | c.687G>A | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734950 | p.Gly233Asn | missense_variant | 0.96 | rifampicin | |
| nusG | 734955 | c.702A>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760046 | c.240G>C | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 760052 | p.Glu82Asp | missense_variant | 0.93 | rifampicin | |
| rpoB | 760059 | c.253_255delTACinsGG | frameshift_variant&missense_variant | 0.96 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760112 | c.306T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760148 | p.Asp114Glu | missense_variant | 0.99 | rifampicin | |
| rpoB | 760155 | p.Lys117Arg | missense_variant | 0.99 | rifampicin | |
| rpoB | 760172 | c.366G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760178 | c.372G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760181 | c.375T>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760235 | c.429T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760317 | c.511_512delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760337 | c.531C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760354 | p.Glu183Ala | missense_variant | 0.99 | rifampicin | |
| rpoB | 760357 | p.Thr184Ser | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 760389 | c.583_585delAGCinsTCG | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 760412 | c.606C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760415 | c.609C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760418 | c.612G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760449 | p.Thr215Leu | missense_variant | 0.99 | rifampicin | |
| rpoB | 760460 | c.654G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760463 | c.657C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760490 | c.684C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760527 | p.Gln241Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Arg | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 760587 | p.Thr261Ala | missense_variant | 0.99 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.99 | rifampicin | |
| rpoB | 760593 | p.Gly263Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 760596 | c.790_792delACCinsTT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760634 | c.828T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760649 | c.843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760718 | c.912C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760721 | c.915C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760724 | c.918T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760734 | p.Val310Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 760748 | c.942C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760880 | c.1074G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760883 | c.1077G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760887 | p.Thr361Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760916 | c.1110C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760964 | c.1158C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760965 | p.Met387Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761171 | c.1365C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761201 | c.1395G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761204 | c.1398C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761220 | c.1414_1416delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761240 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761258 | c.1452G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761318 | c.1512G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761333 | c.1527G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761357 | c.1551G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761465 | c.1659G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761471 | c.1665C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761482 | p.Ala559Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761495 | c.1689G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761502 | c.1696_1698delCCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761508 | c.1702_1704delTCTinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761516 | c.1710G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761627 | c.1821C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761654 | c.1848G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761675 | c.1869G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761705 | c.1899C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761711 | c.1905C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761712 | p.Val636Ile | missense_variant | 0.99 | rifampicin | |
| rpoB | 761723 | p.Glu639Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoB | 761724 | c.1918_1920delGAAinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761728 | p.Ser641Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761760 | p.Ile652Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761777 | c.1971C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761814 | p.Ala670Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761847 | p.Cys681Arg | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761868 | c.2062_2064delGACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761876 | c.2070C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761897 | c.2091C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761903 | c.2097T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 0.99 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762006 | c.2200_2202delCGCinsAG | frameshift_variant&missense_variant | 0.99 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762024 | p.Val740Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762209 | c.2403C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 762212 | c.2406G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762236 | c.2430G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762254 | c.2448T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762278 | c.2472C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762281 | c.2475G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762287 | c.2481C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762335 | c.2529C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762374 | c.-996G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762407 | c.-963G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762410 | c.2604T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762452 | c.2646G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762490 | p.Val895Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 762512 | c.-858C>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 762527 | c.-843G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 762575 | c.-795C>T | upstream_gene_variant | 0.98 | rifampicin | |
| rpoC | 762581 | c.-789T>C | upstream_gene_variant | 0.97 | rifampicin | |
| rpoC | 762582 | c.-788T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762710 | c.-660G>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoB | 762753 | c.2947T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 762760 | p.Cys985Ser | missense_variant | 0.98 | rifampicin | Uncertain significance |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 762788 | c.2982G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 762795 | p.Asp997Asn | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762831 | c.3025_3026delAGinsTC | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762989 | c.3183G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763013 | c.3207C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763050 | c.-320C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763053 | c.3247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763100 | c.-270G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763139 | c.-231C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763142 | c.-228C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 763203 | p.Ser1133Ala | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 763207 | p.Ser1134Lys | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 763214 | c.3408T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763227 | c.3421C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763262 | c.-108C>A | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 763265 | c.-105G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 763272 | c.3466C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763283 | c.3477T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
| rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
| rpoC | 763375 | c.6C>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763396 | c.27A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763430 | c.61A>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763447 | c.78C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763465 | c.96G>A | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763609 | c.240C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763621 | c.252C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763657 | c.288G>A | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763705 | c.336G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763709 | c.340C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763735 | c.366G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763771 | c.402C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763781 | c.412_414delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763790 | p.Glu141Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763867 | c.498C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763885 | c.516C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763918 | c.549G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763930 | c.561G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763936 | c.567C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763947 | p.Ala193Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763960 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763966 | c.597C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763969 | c.600C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763996 | c.627T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764005 | c.636G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 0.99 | rifampicin | |
| rpoC | 764029 | p.Glu220Asp | missense_variant | 0.99 | rifampicin | |
| rpoC | 764030 | p.Asp221Asn | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 764039 | p.Ser224Asp | missense_variant | 0.99 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764048 | p.Thr227Val | missense_variant | 0.99 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764085 | p.Asn239Thr | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 764087 | p.Leu240Val | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 764098 | c.729A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764104 | c.735C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764134 | c.765C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764143 | c.774G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764203 | c.834G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764207 | p.Val280Thr | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 764213 | p.Arg282Lys | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 764248 | c.879C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764254 | c.885G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764255 | c.886C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764317 | c.948C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764320 | c.951C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764410 | c.1041G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764429 | c.1060C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>A | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764548 | c.1179G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764701 | c.1332C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764713 | c.1344G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764752 | c.1383G>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764782 | c.1413C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764863 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764962 | c.1593G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764983 | c.1614T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765277 | c.1908G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765281 | p.Thr638Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765295 | c.1926G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765305 | c.1936_1938delATCinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765339 | p.Gln657Arg | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765404 | p.Leu679Thr | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 765409 | c.2040T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765445 | c.2076G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765453 | p.Ala695Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765508 | c.2139C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765526 | c.2157C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765547 | c.2178C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765548 | c.2179_2181delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765559 | c.2190G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765655 | c.2286T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765662 | c.2293_2295delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765718 | p.Asp783Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765721 | c.2352G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765724 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765742 | p.Glu791Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765790 | c.2421C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765871 | c.2502T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765961 | c.2592G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766009 | c.2640G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766043 | p.Gln892Gly | missense_variant | 0.99 | rifampicin | |
| rpoC | 766061 | p.Val898Ile | missense_variant | 0.98 | rifampicin | |
| rpoC | 766078 | c.2710_2714delCGTGC | frameshift_variant | 0.98 | rifampicin | |
| rpoC | 766087 | c.2718_2719insAGCCG | frameshift_variant | 0.98 | rifampicin | |
| rpoC | 766093 | c.2724C>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766094 | p.Thr909Ser | missense_variant | 0.98 | rifampicin | |
| rpoC | 766113 | p.Tyr915Phe | missense_variant | 0.97 | rifampicin | |
| rpoC | 766120 | c.2751A>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766249 | c.2880C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766258 | c.2889T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766270 | c.2901G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766280 | c.2911_2913delAGCinsGA | frameshift_variant&missense_variant | 0.98 | rifampicin | |
| rpoC | 766288 | c.2919C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766294 | c.2925C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766309 | c.2940G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766312 | c.2943T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766315 | c.2946C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766351 | c.2982C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766366 | c.2997C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766387 | c.3018C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766390 | c.3021C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766459 | c.3090G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766513 | c.3144C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766517 | p.Thr1050Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>A | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766530 | p.Arg1054Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766537 | c.3168G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766546 | p.Glu1059Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 766547 | p.Arg1060Lys | missense_variant | 0.99 | rifampicin | |
| rpoC | 766564 | c.3195C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | c.3238_3240delATCinsTG | frameshift_variant&missense_variant | 0.99 | rifampicin | |
| rpoC | 766610 | p.Ser1081Pro | missense_variant | 1.0 | rifampicin | |
| rpoC | 766618 | c.3249G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766661 | p.Val1098Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766702 | c.3333G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766708 | c.3339A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766747 | c.3378C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766775 | p.Arg1136Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766787 | p.Glu1140Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766807 | c.3438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | c.3514_3516delTCGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766911 | p.Ile1181Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766915 | p.Asp1182Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766931 | c.3562_3564delGCAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766942 | c.3573C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766978 | c.3609C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767032 | c.3663G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767035 | c.3666G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | c.3736_3738delAACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767152 | c.3783T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767278 | c.3909T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767284 | c.3915C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775720 | p.Val921Ile | missense_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775735 | p.Phe916Leu | missense_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775736 | c.2745C>G | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775742 | c.2739C>A | synonymous_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775747 | p.Met912Leu | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775763 | c.2718T>C | synonymous_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775770 | p.Ala904Gly | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775772 | p.Met903Ile | missense_variant | 0.96 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775778 | p.Thr901Arg | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775784 | c.2697G>A | synonymous_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775793 | c.2688C>G | synonymous_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775796 | c.2683_2685delTTTinsAG | frameshift_variant&stop_gained | 0.96 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775801 | p.Ser894Thr | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775817 | c.2664T>C | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mmpL5 | 775826 | c.2655G>A | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775829 | c.2652C>G | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775832 | c.2649C>G | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775856 | c.2625T>C | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775862 | c.2619G>C | synonymous_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775865 | c.2616T>C | synonymous_variant | 0.98 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775871 | p.Ile870Met | missense_variant | 0.96 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775880 | c.2599_2601delAACinsCT | frameshift_variant&missense_variant | 0.97 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775883 | c.2596_2598delATCinsCG | frameshift_variant&missense_variant | 0.94 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775886 | c.2595A>G | synonymous_variant | 0.97 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775904 | p.Lys859Arg | missense_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775907 | c.2574C>G | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775913 | c.2566_2568delGCCinsTG | frameshift_variant&missense_variant | 0.96 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775916 | c.2565T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775922 | c.2559G>A | synonymous_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.74 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.74 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775954 | c.2527C>T | synonymous_variant | 0.64 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.91 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775970 | c.2511G>C | synonymous_variant | 0.52 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775975 | c.2506T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781549 | c.-11A>G | upstream_gene_variant | 0.9 | streptomycin | |
| rpsL | 781571 | c.12C>T | synonymous_variant | 0.98 | streptomycin | |
| rpsL | 781595 | c.36T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781608 | c.49_51delAGTinsGC | frameshift_variant&missense_variant | 0.99 | streptomycin | Uncertain significance |
| rpsL | 781613 | c.54G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781622 | c.63C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781652 | c.93T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781724 | c.165G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781877 | c.318T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781904 | c.345C>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 0.99 | streptomycin | Uncertain significance |
| rplC | 800480 | c.-329G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800498 | c.-311G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800516 | c.-293G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.99 | linezolid | |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800558 | c.-251G>A | upstream_gene_variant | 0.99 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800570 | c.-239C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800574 | c.-235_-234delGTinsAC | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800594 | c.-215C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800597 | c.-212A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800702 | c.-107G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 0.96 | linezolid | |
| rplC | 800856 | c.48A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 0.97 | linezolid | |
| rplC | 800873 | p.Arg22Lys | missense_variant | 0.97 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 800880 | c.72A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 800886 | c.78G>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 800892 | c.84G>C | synonymous_variant | 0.95 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 800931 | c.123G>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 800950 | c.142_143delAGinsTC | synonymous_variant | 0.97 | linezolid | |
| rplC | 800964 | c.156G>C | synonymous_variant | 0.99 | linezolid | |
| rplC | 800967 | c.159C>T | synonymous_variant | 0.99 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 0.99 | linezolid | Not assoc w R - Interim |
| rplC | 800985 | c.177A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 801006 | c.198G>C | synonymous_variant | 0.96 | linezolid | |
| rplC | 801009 | c.201A>C | synonymous_variant | 0.96 | linezolid | |
| rplC | 801019 | c.211_213delACCinsGA | frameshift_variant&missense_variant | 0.96 | linezolid | |
| rplC | 801024 | c.216C>G | synonymous_variant | 0.96 | linezolid | |
| rplC | 801030 | c.222C>G | synonymous_variant | 0.96 | linezolid | |
| rplC | 801039 | c.231A>C | synonymous_variant | 0.95 | linezolid | |
| rplC | 801045 | c.237A>G | synonymous_variant | 0.96 | linezolid | |
| rplC | 801046 | p.Tyr80His | missense_variant | 0.96 | linezolid | |
| rplC | 801054 | c.246G>C | synonymous_variant | 0.93 | linezolid | |
| rplC | 801058 | c.250C>T | synonymous_variant | 0.9 | linezolid | |
| rplC | 801117 | c.309G>C | synonymous_variant | 0.94 | linezolid | |
| rplC | 801132 | c.324T>C | synonymous_variant | 0.96 | linezolid | |
| rplC | 801136 | p.Ser110Ala | missense_variant | 1.0 | linezolid | |
| rplC | 801147 | c.339T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801153 | c.345G>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 801156 | c.348T>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 801171 | c.363A>G | synonymous_variant | 0.98 | linezolid | |
| rplC | 801174 | c.366T>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 801176 | p.Phe123Tyr | missense_variant | 0.98 | linezolid | |
| rplC | 801220 | c.412_414delAGTinsGG | frameshift_variant&missense_variant | 0.99 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 0.99 | linezolid | |
| rplC | 801249 | c.441T>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 801258 | c.450C>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 801267 | c.459A>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 801271 | c.463_465delGCCinsTG | frameshift_variant&missense_variant | 0.98 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 801281 | p.Ala158Gly | missense_variant | 0.98 | linezolid | |
| rplC | 801307 | c.499_501delGCCinsTG | frameshift_variant&missense_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801330 | c.522G>C | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303455 | c.525C>T | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303464 | c.534A>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303488 | c.558G>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303492 | c.562T>C | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303500 | c.570C>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>G | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303581 | c.651G>C | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303611 | c.681G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303632 | c.702T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303641 | p.Asp237Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304845 | p.Ala639Thr | missense_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304853 | c.1923C>G | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304857 | p.Thr643Ser | missense_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304868 | c.1938G>C | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304874 | c.1944C>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304880 | c.1950C>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304915 | p.Asp662Gly | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304918 | p.Thr663Ser | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305126 | c.2196T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1305135 | c.2205C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305144 | c.2214G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305154 | c.2224T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305173 | p.Asn748Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305177 | c.2247A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305181 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305186 | c.2256C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305197 | p.Ala756Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305204 | c.2274C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305213 | c.2283C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305219 | c.2289T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305222 | c.2292C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305231 | c.2301C>T | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305237 | c.2307A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305240 | c.2310T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305243 | c.2313T>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305244 | c.2314T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305259 | c.2329T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305277 | p.His783Asn | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305297 | c.2367G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305300 | c.2370A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305303 | c.2373T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305306 | c.2376A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305310 | p.Arg794Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305339 | c.2409C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305348 | c.2418C>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305360 | c.2430G>C | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305361 | c.2431C>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305381 | c.2451G>C | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305393 | c.2463T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305399 | c.2469A>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305405 | c.2475A>G | synonymous_variant | 0.95 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305418 | p.Val830Ile | missense_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305423 | c.2493T>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305427 | c.2497C>T | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305432 | c.2502C>T | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305444 | c.2514A>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305462 | c.2532G>T | synonymous_variant | 0.9 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1305465 | c.2535C>G | synonymous_variant | 0.89 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364811 | c.399A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364826 | c.414C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364856 | c.444C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364862 | c.450C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364867 | p.Ala152Gly | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364871 | c.459C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364872 | c.460_462delATCinsGT | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364886 | c.474G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364898 | c.486C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364913 | c.501C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364926 | c.514_516delAACinsGT | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364960 | p.Gly183Asp | missense_variant | 0.94 | pyrazinamide | |
| sigE | 1364964 | c.552T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364967 | c.555C>T | synonymous_variant | 0.93 | pyrazinamide | |
| sigE | 1364976 | c.564T>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364979 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364980 | c.568T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364984 | p.Ala191Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364988 | c.576G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364989 | c.577C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364992 | p.Pro194Ala | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1365003 | c.591T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365006 | c.594T>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365009 | c.597C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365012 | c.600G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365015 | c.603G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365039 | c.627G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365042 | c.630G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365052 | p.Ile214Val | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1365057 | c.645C>G | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1461083 | c.39T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461086 | c.42A>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461107 | c.63C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461113 | c.69C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461131 | c.87T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461137 | c.93C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461140 | c.96T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461143 | c.99C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461158 | c.114T>A | synonymous_variant | 0.98 | bedaquiline | |
| atpE | 1461159 | p.Val39Ile | missense_variant | 0.98 | bedaquiline | Uncertain significance |
| atpE | 1461170 | c.126A>G | synonymous_variant | 0.99 | bedaquiline | |
| atpE | 1461179 | c.135G>T | synonymous_variant | 0.99 | bedaquiline | |
| atpE | 1461182 | c.138A>G | synonymous_variant | 0.98 | bedaquiline | |
| atpE | 1461185 | c.141G>C | synonymous_variant | 0.98 | bedaquiline | |
| atpE | 1461197 | c.153A>C | synonymous_variant | 0.99 | bedaquiline | |
| atpE | 1461212 | c.168C>G | synonymous_variant | 0.99 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 0.98 | bedaquiline | |
| atpE | 1461224 | c.180T>C | synonymous_variant | 0.98 | bedaquiline | |
| atpE | 1461233 | c.189A>C | synonymous_variant | 0.98 | bedaquiline | |
| atpE | 1461254 | c.210T>C | synonymous_variant | 0.97 | bedaquiline | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471926 | n.81C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471937 | n.93dupT | non_coding_transcript_exon_variant | 0.45 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471985 | n.140T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472042 | n.197T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472292 | n.447A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472298 | n.453G>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472302 | n.457_458insT | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472310 | n.465_466insG | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472314 | n.469A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472683 | n.838_839insTA | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473100 | n.1255G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473109 | n.1264T>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473111 | n.1266A>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473123 | n.1278A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445delCinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473668 | n.11C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473807 | n.150T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473812 | n.155G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473814 | n.157A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473815 | n.158T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473816 | n.159C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473828 | n.171_175delGGTGCinsCCGGTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1473887 | n.230delTinsAA | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474202 | n.545T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474287 | n.630_649delTCCTTTTCCTCTCCGGAGGAinsCTCGTT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474350 | n.693G>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474351 | n.694G>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474374 | n.717T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474452 | n.795C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474638 | n.981C>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474708 | n.1052dupG | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474711 | n.1054_1055insA | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1474715 | n.1061delA | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474952 | n.1296delC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474957 | n.1301_1308delACCTTGTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474968 | n.1311_1315delGGGTGinsCAGGAT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474990 | n.1333C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474991 | n.1334T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474995 | n.1338T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474997 | n.1340A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474999 | n.1342C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475008 | n.1351C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475017 | n.1360delGinsTA | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475031 | n.1374G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475037 | n.1380T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475062 | n.1405A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475120 | n.1463G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475240 | n.1583C>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475241 | n.1584C>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475242 | n.1585G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475244 | n.1587A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475252 | n.1595C>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475257 | n.1600_1614delCTTCGGGGGTGTGGAinsTTCGGGGTGCGAC | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475273 | n.1616T>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1475276 | n.1619T>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1475277 | n.1620G>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1475278 | n.1621G>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475363 | n.1706C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475375 | n.1718G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475378 | n.1721A>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475379 | n.1722G>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475380 | n.1723C>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475396 | n.1739_1740insTG | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475399 | n.1742T>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1475400 | n.1743C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1475408 | n.1752delT | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475428 | n.1771G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475433 | n.1776A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475458 | n.1801C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475460 | n.1803A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475482 | n.1825A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475603 | n.1946G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475629 | n.1972_1973insC | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475762 | n.2105_2108delGCAAinsCTTCG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476103 | n.2446C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476108 | n.2451T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476246 | n.2589G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476262 | n.2605G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476517 | n.2860C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476529 | n.2872A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476665 | n.3008T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476679 | n.3022T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476692 | n.3035T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476731 | n.3074G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476741 | n.3084G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476746 | n.3089T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476748 | n.3091A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476753 | n.3096T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476754 | n.3097G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476755 | n.3098G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476758 | n.3101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476770 | n.3113T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476771 | n.3114G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673646 | c.-556T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673649 | c.-553C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673652 | c.-550C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673657 | p.Thr73Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673660 | p.Ala74Glu | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673679 | c.-523T>C | upstream_gene_variant | 0.98 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1673685 | c.-517C>G | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673709 | c.-493C>T | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673710 | c.271_273delCTAinsAC | frameshift_variant&missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673716 | p.Ala93Lys | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673724 | c.-478A>C | upstream_gene_variant | 0.98 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1673727 | c.-475C>T | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673730 | c.-472C>G | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673748 | c.-454A>G | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673749 | p.Lys104Arg | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673757 | c.-445G>A | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673758 | p.Lys107Glu | missense_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673778 | c.-424C>G | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673787 | c.-415G>A | upstream_gene_variant | 0.98 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673796 | c.-406G>C | upstream_gene_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673799 | c.-403T>G | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673805 | c.-397G>C | upstream_gene_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673811 | c.-391G>A | upstream_gene_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673895 | c.-307C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673901 | c.-301A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673905 | p.Ser156Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673916 | c.-286A>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673917 | p.Val160Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673941 | p.Ala168Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673955 | c.-247G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673961 | c.-241A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673962 | p.Asn175Gly | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673967 | c.-235G>C | upstream_gene_variant | 1.0 | ethionamide |