TB-Profiler result

Run: b7d12098-b6b4-43f3-b667-869c7389aca4

Summary

Run ID: b7d12098-b6b4-43f3-b667-869c7389aca4

Sample name:

Date: 06-02-2023 10:10:32

Number of reads: 60777

Percentage reads mapped: 10.81

Median coverage: 4

Strain:

Spoligotype:

Drug-resistance: MDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.84
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser428Arg Assoc w R - interim
p.Ser472Ala Uncertain significance
isoniazid kasA p.Arg121Lys Uncertain significance
ethambutol embB p.Met423Ile Uncertain significance
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin
amikacin
kanamycin
capreomycin tlyA c.90delC Uncertain significance
c.93_94insC Uncertain significance
c.235delA Uncertain significance
clofazimine
ethionamide ethA c.1333delG Uncertain significance
c.372_373insG Uncertain significance
c.315_316delCA Uncertain significance
c.244delC Uncertain significance
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761090 p.Ser428Arg missense_variant 0.77 rifampicin Assoc w R - interim
rpoB 761220 p.Ser472Ala missense_variant 0.93 rifampicin Uncertain significance
tlyA 1918028 c.90delC frameshift_variant 0.86 capreomycin Uncertain significance
tlyA 1918032 c.93_94insC frameshift_variant 0.83 capreomycin Uncertain significance
tlyA 1918173 c.235delA frameshift_variant 0.9 capreomycin Uncertain significance
kasA 2518476 p.Arg121Lys missense_variant 0.97 isoniazid Uncertain significance
embB 4247782 p.Met423Ile missense_variant 0.83 ethambutol Uncertain significance
ethA 4326140 c.1333delG frameshift_variant 0.93 ethionamide Uncertain significance
ethA 4327101 c.372_373insG frameshift_variant 0.86 ethionamide Uncertain significance
ethA 4327157 c.315_316delCA frameshift_variant 0.89 ethionamide Uncertain significance
ethA 4327229 c.244delC frameshift_variant 0.91 ethionamide Uncertain significance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5199 c.-41T>G upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5211 c.-29A>C upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5214 c.-26_-25insG upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5222 c.-18G>A upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5229 c.-11G>C upstream_gene_variant 0.71 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5230 c.-10T>G upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5231 c.-9A>C upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5232 c.-8T>G upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5235 c.-5G>C upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5237 c.-2delT upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5254 c.15A>G synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5260 p.Lys7Asn missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5268 p.Asp10Ala missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5272 c.33A>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5281 c.42T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5284 c.45G>T synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5287 c.48T>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5292 p.Thr18Lys missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5294 p.Ile19Val missense_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5305 c.66G>A synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5317 c.78C>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5320 c.81C>T synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5329 c.90C>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5341 c.102T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5344 c.105C>T synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5347 c.108G>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5359 c.120C>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5363 c.124_126delTTAinsCTG synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5371 c.132T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5374 c.135C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5375 p.Ile46Val missense_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5386 c.147G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5401 c.162C>A synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5421 p.Tyr61Phe missense_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5425 c.186A>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5427 p.Thr63Ser missense_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5430 p.Thr64Lys missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5434 c.195G>C synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5435 p.Asn66Asp missense_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5446 c.207G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5449 c.210T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5461 c.222T>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5465 p.Glu76Gln missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5471 p.Ala78Thr missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 5488 c.249C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5497 c.258C>G synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5503 c.264C>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5509 c.270C>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5510 p.Ser91Thr missense_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5515 c.276C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5518 c.279A>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5530 c.291C>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5533 c.294G>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5545 p.Gln102His missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5551 c.312T>C synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5571 p.Ser111* stop_gained 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5585 p.Ile116Val missense_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5590 c.351T>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5593 c.354T>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5608 c.369C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5611 c.372C>T synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5617 c.378G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5623 c.384T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5629 c.390G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5632 c.393A>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5635 c.396C>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5653 p.Glu138Asp missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5659 c.421_423delCGC conservative_inframe_deletion 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5668 c.429G>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5679 p.Ser147Phe missense_variant 0.93 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 5684 p.Val149Thr missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5689 c.450T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5692 p.Glu151Asp missense_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5695 p.Lys152Asn missense_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5700 p.Glu154Val missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5703 c.465_467delCCT disruptive_inframe_deletion 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5724 p.Ala162Val missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5726 p.Pro163Thr missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5734 p.Lys165Asn missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5740 c.501G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5744 p.Ser169Thr missense_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5749 c.510G>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5750 p.Val171Ile missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5764 c.525C>T synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5771 p.Ala178Asn missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5776 c.537T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5782 c.543A>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5790 p.Glu184Val missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5803 c.564A>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5807 p.Val190Ile missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5815 c.576C>T synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5818 c.579G>T synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5824 c.585A>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5833 c.594G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5848 c.609G>C synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5854 c.615C>G synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5858 p.Asn207Asp missense_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 5863 c.624G>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5873 c.634A>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5879 p.Thr214Ser missense_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5884 c.645A>G synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5887 p.Asp216Glu missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5902 c.663A>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5909 p.Ser224Ala missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5915 p.Val226Thr missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5922 p.Glu228Ala missense_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5926 c.687G>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5932 c.693G>A synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5943 c.704_705insG frameshift_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5946 c.708delC frameshift_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5950 c.711A>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5956 c.717A>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5957 p.Ser240Ala missense_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5960 p.Thr241Ala missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5965 c.726A>G synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5968 c.729G>C synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5974 c.735A>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5977 c.738T>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5981 p.Ser248His missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5986 c.747C>G synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5992 c.753T>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5998 c.759T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6004 c.765T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6007 c.768C>T synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6013 c.774G>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6022 c.783G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6025 c.786A>G synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6045 p.Asn269Thr missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6052 c.813T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6055 p.His272Gln missense_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6069 c.831_832delCT frameshift_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6091 c.852G>T synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6100 c.861G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6115 c.876A>G synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6121 c.882C>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6127 c.888G>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6130 c.891T>C synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6142 c.903G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6145 c.906C>T synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6148 c.909C>G synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6160 c.921C>G synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6169 c.930C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6181 c.942C>T synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6196 c.957C>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6208 c.969G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6214 c.975G>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 6250 c.1011A>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6307 c.-995T>G upstream_gene_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6310 c.-992G>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6325 c.-977C>G upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6329 p.Glu364Gln missense_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6343 c.-959G>A upstream_gene_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6398 p.Val387Ile missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6433 c.-869C>G upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6436 c.-866C>T upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6440 p.Thr401Ala missense_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 6445 p.Asp402Glu missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 6448 c.-854G>C upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6452 p.Val405Thr missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6457 c.-845T>G upstream_gene_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6466 c.-836G>A upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6469 c.-833T>A upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6472 c.-830G>T upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6475 c.-827C>A upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6484 c.-818A>G upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6487 c.-815C>G upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6499 c.-803A>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6502 c.-800T>C upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6511 c.-791A>T upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6515 c.-787T>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6520 c.-782G>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6550 c.-752A>C upstream_gene_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6551 c.-751T>C upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6565 c.-737G>C upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6568 c.-734C>G upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6577 c.-725T>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6580 c.-722C>T upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6591 c.1353delC frameshift_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6685 c.-617C>G upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6715 c.-587C>T upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6763 c.-539G>C upstream_gene_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6775 c.-527G>C upstream_gene_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6793 c.-509T>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6797 p.Gly520Ser missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6811 c.-491C>T upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6824 c.-478C>T upstream_gene_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6841 c.-461T>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6856 c.-446T>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6859 c.-443T>C upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6865 c.-437G>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6878 c.-424T>C upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6881 c.-421T>C upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6897 p.Arg553Gln missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6905 p.Ile556Val missense_variant 0.97 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6911 p.Asn558His missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6919 c.-383T>C upstream_gene_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6920 p.Val561Ile missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6925 c.-377T>C upstream_gene_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6926 c.-376T>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6931 c.-371A>C upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6963 c.1724_1725insT frameshift_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6967 p.Ser576Arg missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6970 p.Asp577Glu missense_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6982 c.-320A>G upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7012 c.-290G>C upstream_gene_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7037 p.Lys600Arg missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7045 c.-257C>T upstream_gene_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7046 p.Lys603Val missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7057 c.-245C>T upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7060 c.-242T>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7066 c.-236G>T upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7093 c.-209T>C upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7100 c.-202T>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7135 c.-167G>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7138 c.-164G>A upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7153 c.-149G>C upstream_gene_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7156 c.-146C>T upstream_gene_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7159 c.-143C>T upstream_gene_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7198 c.-104C>T upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7213 c.-89G>C upstream_gene_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7216 c.-86G>C upstream_gene_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7222 c.-80C>T upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7231 c.-71C>G upstream_gene_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7243 c.-59G>A upstream_gene_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7246 c.-56T>C upstream_gene_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7261 c.-41T>C upstream_gene_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7264 c.-38C>T upstream_gene_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7270 c.-32C>G upstream_gene_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7299 c.-3T>C upstream_gene_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7301 c.-1G>C upstream_gene_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7307 c.6A>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7313 c.12G>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7322 c.21G>A synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7325 c.24T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7327 p.Asp9Gly missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7343 c.42G>T synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7355 c.54T>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7361 c.60C>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7362 p.Glu21Gln missense_variant 0.96 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7367 p.Gln22His missense_variant 0.94 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7394 c.93T>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7397 c.96G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7421 c.120G>T synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7436 c.135C>T synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7442 c.141G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7457 c.156T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7460 c.159C>G synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7463 c.162G>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7472 c.171T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7475 c.174A>G synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7480 p.Phe60Tyr missense_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7484 c.183T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7487 c.186C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7520 c.219G>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7523 c.222C>A synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7526 c.225G>T synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7532 c.231T>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7541 c.240C>G synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7547 c.246C>T synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7559 c.258G>A synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7569 p.Ala90Ser missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7585 p.Ser95Thr missense_variant 0.98 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7592 c.291G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7595 c.294C>G synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7614 c.313C>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7631 c.330G>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7643 c.342C>A synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7655 c.354G>A synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7658 c.357A>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7661 c.360C>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7664 c.363T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7670 c.369A>G synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7683 c.382_384delAGGinsCGT synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7694 c.393A>G synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7706 c.405C>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7710 c.409T>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7715 c.414G>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7725 c.424C>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7728 c.427A>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7754 p.Asp151Glu missense_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7763 c.462T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7784 c.483A>G synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7787 c.486G>A synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7790 c.489G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7793 c.492G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7799 c.498A>G synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7802 c.501C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7835 c.534A>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7841 c.540C>T synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7847 c.546G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7859 c.558A>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7862 c.561C>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7865 c.564T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7886 c.585T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7906 p.Phe202Tyr missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7912 c.612delG frameshift_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7919 c.618G>A synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7922 c.621T>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7928 p.Asp209Glu missense_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7934 c.633C>T synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7942 p.Glu214Ala missense_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7970 c.669T>C synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7979 c.678G>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7988 c.687G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7992 p.Ala231Ser missense_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7997 c.696A>T synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8022 p.Ala241Thr missense_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8023 c.723delT frameshift_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8027 c.726T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8035 p.Lys245Thr missense_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8039 c.738T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8054 c.753T>C synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8057 c.756A>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8066 c.765A>T synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8072 c.771T>G synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8076 p.Val259Ile missense_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8084 c.783G>A synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8087 c.786T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8088 c.787_788delTCinsAG synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8093 c.792C>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8096 c.795T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8099 c.798T>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8108 c.807G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8120 c.819G>A synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8121 c.820T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8126 c.825G>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8129 c.828T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8156 c.855T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8168 c.867A>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8174 c.873C>G synonymous_variant 0.79 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8177 c.876A>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8198 c.897T>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8207 c.906T>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8225 c.924T>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8234 c.933T>A synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8243 c.942C>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8246 c.945C>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8247 p.Ile316Val missense_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8267 c.966G>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8270 c.969G>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8288 c.987T>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8294 c.993T>C synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8337 c.1036_1038delCTAinsTTG synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8360 c.1059G>A synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8366 c.1065G>A synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8426 c.1125G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8429 c.1128C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8434 p.Thr378Ser missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8489 c.1188A>G synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8492 c.1191G>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8495 c.1194C>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8501 c.1200G>A synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8519 c.1218A>T synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8531 c.1230G>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8543 c.1242C>A synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8546 p.Asp415Glu missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8585 c.1284C>T synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8624 c.1323G>T synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8630 c.1329G>T synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8633 c.1332C>T synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8655 p.Ile452Val missense_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8738 c.1437G>T synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8750 c.1449C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8762 c.1461G>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8765 p.Asp488Glu missense_variant 0.92 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8767 p.Arg489Lys missense_variant 0.96 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8783 c.1482G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8786 c.1485T>G synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.98 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8819 c.1518C>T synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8849 c.1548C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8873 c.1572A>G synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8894 c.1593C>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8900 c.1599G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8903 c.1602T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8915 c.1614A>G synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8936 c.1635G>A synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9017 c.1716C>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9060 p.Ala587Thr missense_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9092 c.1791C>G synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9098 c.1797G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9113 c.1812C>G synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9146 c.1845C>A synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9147 c.1846_1847insA frameshift_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9191 c.1890G>T synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.74 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9208 p.Lys636Arg missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9213 p.Thr638Val missense_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9227 c.1926C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9266 p.Asp655Glu missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.76 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9304 p.Gly668Asp missense_variant 0.98 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9368 c.2067G>C synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9369 c.2068C>T synonymous_variant 0.73 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9374 c.2073G>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9383 c.2082T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9398 c.2097T>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.99 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9420 p.Ile707Glu missense_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9425 c.2124C>T synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9440 c.2139G>C synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9443 c.2142G>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9446 c.2145C>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9464 c.2163C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9476 c.2175G>T synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9482 c.2181G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9483 p.Ser728Ala missense_variant 0.94 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9500 c.2199A>G synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9503 c.2202T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9506 c.2205C>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9515 p.Glu738Asp missense_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9522 p.Pro741Thr missense_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9527 c.2226A>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9533 c.2232C>T synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9536 c.2235C>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9542 c.2241T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9548 c.2247T>C synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9549 p.Val750Ile missense_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9558 p.Val753Phe missense_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9573 p.Arg758Lys missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9578 c.2277C>T synonymous_variant 0.9 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9584 p.Arg761Ser missense_variant 0.77 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9585 c.2284T>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9590 c.2289T>C synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9593 c.2292G>A synonymous_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9597 c.2296T>C synonymous_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.97 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9608 c.2307C>T synonymous_variant 0.98 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9614 p.Asp771Glu missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9616 p.Ser772Thr missense_variant 0.75 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9626 c.2325T>C synonymous_variant 0.94 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9630 p.Val777Ile missense_variant 0.91 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9641 c.2340C>T synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9662 c.2361G>T synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9668 c.2367C>T synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9680 c.2379G>A synonymous_variant 0.84 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9683 c.2382G>T synonymous_variant 0.88 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9686 c.2385A>G synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9689 c.2388G>T synonymous_variant 0.92 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9701 c.2400T>C synonymous_variant 0.95 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9707 c.2406G>C synonymous_variant 0.89 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9716 c.2415T>C synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9738 p.Leu813Ile missense_variant 0.78 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9743 c.2442C>G synonymous_variant 0.96 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9746 c.2445C>T synonymous_variant 0.93 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9761 c.2460A>G synonymous_variant 0.81 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9776 p.Asp825Glu missense_variant 0.73 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
fgd1 491295 c.513C>G synonymous_variant 0.8 delamanid
fgd1 491462 p.Lys227Arg missense_variant 0.73 delamanid
mshA 575153 c.-195C>G upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 575154 c.-194G>C upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 575162 c.-186T>C upstream_gene_variant 0.85 ethionamide
isoniazid
mshA 575168 c.-180C>T upstream_gene_variant 0.78 ethionamide
isoniazid
mshA 575177 c.-171G>C upstream_gene_variant 0.91 ethionamide
isoniazid
mshA 575187 c.-161_-159delGGGinsAGT upstream_gene_variant 0.73 ethionamide
isoniazid
mshA 575201 c.-147G>T upstream_gene_variant 0.91 ethionamide
isoniazid
mshA 575204 c.-144C>G upstream_gene_variant 0.9 ethionamide
isoniazid
mshA 575207 c.-141A>G upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 575208 c.-140A>G upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 575213 c.-135G>T upstream_gene_variant 0.84 ethionamide
isoniazid
mshA 575219 c.-129T>C upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 575222 c.-126C>G upstream_gene_variant 0.81 ethionamide
isoniazid
mshA 575228 c.-120A>G upstream_gene_variant 0.73 ethionamide
isoniazid
mshA 575234 c.-114T>C upstream_gene_variant 0.78 ethionamide Uncertain significance
isoniazid
mshA 575238 c.-110T>A upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 575392 c.45G>A synonymous_variant 0.71 ethionamide
isoniazid
mshA 575397 c.51delT frameshift_variant 0.9 ethionamide
isoniazid
mshA 575416 c.69T>G synonymous_variant 0.84 ethionamide
isoniazid
mshA 575444 p.Pro33Thr missense_variant 0.89 ethionamide
isoniazid
mshA 575453 c.106C>A synonymous_variant 0.81 ethionamide
isoniazid
mshA 575479 c.132G>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575485 c.138G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575492 p.Leu49Val missense_variant 0.91 ethionamide
isoniazid
mshA 575495 p.Leu50Ile missense_variant 0.9 ethionamide
isoniazid
mshA 575498 p.Ala51Ser missense_variant 0.86 ethionamide
isoniazid
mshA 575503 c.156G>A synonymous_variant 0.86 ethionamide
isoniazid
mshA 575512 c.165A>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575521 c.174A>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 0.87 ethionamide
isoniazid
mshA 575548 c.201C>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575554 c.207C>T synonymous_variant 0.91 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.84 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.85 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.91 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.91 ethionamide
isoniazid
mshA 575581 p.His78Gln missense_variant 0.91 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575593 c.246G>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575597 p.Ile84Val missense_variant 0.96 ethionamide
isoniazid
mshA 575609 p.Ile88Val missense_variant 0.92 ethionamide
isoniazid
mshA 575627 p.Ala94Ser missense_variant 0.95 ethionamide
isoniazid
mshA 575633 p.Ala96Ser missense_variant 0.95 ethionamide
isoniazid
mshA 575639 p.Pro98Ala missense_variant 0.81 ethionamide
isoniazid
mshA 575652 p.Arg102Pro missense_variant 0.95 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 575669 c.322C>T synonymous_variant 0.88 ethionamide
isoniazid
mshA 575680 c.333C>T synonymous_variant 0.84 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 0.81 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575704 c.357T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575728 c.381C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.88 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.74 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.94 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.75 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.94 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575869 c.522G>T synonymous_variant 0.85 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.81 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575890 c.543C>A synonymous_variant 0.9 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575905 c.558G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575906 p.Ala187Ser missense_variant 0.96 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 0.99 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.99 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 0.95 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.78 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575977 c.630G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575983 c.636G>A synonymous_variant 0.93 ethionamide
isoniazid
mshA 575984 c.637_639delTTGinsCTC synonymous_variant 0.92 ethionamide
isoniazid
mshA 576001 p.Asp218Glu missense_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576002 p.Asp219His missense_variant 0.94 ethionamide
isoniazid
mshA 576016 c.669A>G synonymous_variant 0.88 ethionamide
isoniazid
mshA 576020 p.Ile225Val missense_variant 0.95 ethionamide
isoniazid
mshA 576031 c.684T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576032 p.Gly229His missense_variant 0.93 ethionamide
isoniazid
mshA 576045 p.Ala233Gly missense_variant 0.97 ethionamide
isoniazid
mshA 576049 c.702A>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 576055 c.708C>T synonymous_variant 0.93 ethionamide
isoniazid
mshA 576058 c.711G>A synonymous_variant 0.74 ethionamide
isoniazid
mshA 576061 c.714C>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 576070 c.723T>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 576073 c.726C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 576076 c.729T>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 576082 c.735C>T synonymous_variant 0.82 ethionamide
isoniazid
mshA 576084 p.Val246Ala missense_variant 0.83 ethionamide
isoniazid
mshA 576120 p.Ala258Val missense_variant 0.86 ethionamide
isoniazid
mshA 576124 c.777A>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 576128 c.781_783delCTAinsTTG synonymous_variant 0.87 ethionamide
isoniazid
mshA 576131 c.785_786delCA frameshift_variant 1.0 ethionamide
isoniazid
mshA 576144 p.Arg266Gln missense_variant 0.74 ethionamide
isoniazid
mshA 576154 c.807C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 576160 c.813C>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 576163 c.816A>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 576166 c.819C>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 576178 c.831G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 576184 c.837A>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 576191 p.Ile282Val missense_variant 0.88 ethionamide
isoniazid
mshA 576202 c.855T>G synonymous_variant 0.85 ethionamide
isoniazid
mshA 576205 c.858G>T synonymous_variant 0.85 ethionamide
isoniazid
mshA 576214 c.867G>A synonymous_variant 0.75 ethionamide
isoniazid
mshA 576215 c.868T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 576226 c.879G>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 576229 c.882C>G synonymous_variant 0.88 ethionamide
isoniazid
mshA 576230 p.Ile295Val missense_variant 0.85 ethionamide
isoniazid
mshA 576247 c.900A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 576250 c.903G>A synonymous_variant 0.84 ethionamide
isoniazid
mshA 576259 c.912C>T synonymous_variant 0.82 ethionamide
isoniazid
mshA 576262 c.915T>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 576269 p.Ser308Ala missense_variant 0.85 ethionamide
isoniazid
mshA 576274 c.927G>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 576278 p.Gly311Thr missense_variant 0.86 ethionamide
isoniazid
mshA 576286 c.939C>T synonymous_variant 0.82 ethionamide
isoniazid
mshA 576289 c.942G>T synonymous_variant 0.91 ethionamide
isoniazid
mshA 576292 c.945C>T synonymous_variant 0.88 ethionamide
isoniazid
mshA 576307 c.960C>T synonymous_variant 0.8 ethionamide
isoniazid
mshA 576311 p.Ser322Thr missense_variant 0.92 ethionamide
isoniazid
mshA 576315 p.Ala323Asp missense_variant 0.86 ethionamide
isoniazid
mshA 576319 c.972G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 576328 c.981T>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 576334 c.987G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 576345 p.His333Arg missense_variant 0.89 ethionamide
isoniazid
mshA 576350 c.1004delA frameshift_variant 0.96 ethionamide
isoniazid
mshA 576357 p.Ala337Val missense_variant 0.86 ethionamide
isoniazid
mshA 576360 p.Thr338Asn missense_variant 0.91 ethionamide
isoniazid
mshA 576362 p.Leu339Val missense_variant 0.98 ethionamide
isoniazid
mshA 576366 p.Phe340Tyr missense_variant 0.97 ethionamide
isoniazid
mshA 576370 c.1023G>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 576373 c.1026G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 576376 c.1029G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576379 c.1032C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 576385 c.1038T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576394 c.1047G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 576421 c.1074T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 576424 c.1077T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 576425 p.Val360Ile missense_variant 0.9 ethionamide
isoniazid
mshA 576436 c.1089A>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 576439 c.1092G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 576445 c.1098C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 576448 c.1101A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 576451 c.1104G>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 576460 c.1113C>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 576463 c.1116G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 576469 c.1122G>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576475 c.1128G>T synonymous_variant 0.97 ethionamide
isoniazid
mshA 576481 c.1134C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 576491 p.Arg382Ala missense_variant 0.86 ethionamide
isoniazid
mshA 576500 p.Ile385Val missense_variant 0.95 ethionamide
isoniazid
mshA 576504 p.Thr386Ser missense_variant 0.85 ethionamide
isoniazid
mshA 576509 p.Thr388Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid
mshA 576517 c.1170G>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 576518 p.Ser391Asp missense_variant 0.95 ethionamide
isoniazid
mshA 576523 c.1176G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 576529 p.Glu394Asp missense_variant 0.98 ethionamide
isoniazid
mshA 576534 p.Gly396Asp missense_variant 0.82 ethionamide
isoniazid
mshA 576536 p.Gln397Asp missense_variant 0.93 ethionamide
isoniazid
mshA 576544 c.1197C>G synonymous_variant 0.79 ethionamide
isoniazid
mshA 576546 p.Asp400Ala missense_variant 0.87 ethionamide
isoniazid
mshA 576557 p.His404Gly missense_variant 0.82 ethionamide
isoniazid
mshA 576560 p.Leu405Val missense_variant 0.82 ethionamide
isoniazid
mshA 576570 p.Leu408Ser missense_variant 0.75 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576572 p.Cys409Arg missense_variant 0.86 ethionamide
isoniazid
mshA 576599 p.Ser418Arg missense_variant 0.94 ethionamide
isoniazid
mshA 576607 c.1260G>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 576613 c.1266A>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 576634 c.1287G>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 576639 p.Glu431Ala missense_variant 0.92 ethionamide
isoniazid
mshA 576641 p.Asn432His missense_variant 0.88 ethionamide
isoniazid
mshA 576647 p.Thr434Val missense_variant 0.92 ethionamide
isoniazid
mshA 576655 c.1308G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 576659 c.1312T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 576662 p.Ala439Asn missense_variant 0.91 ethionamide
isoniazid
mshA 576667 c.1320T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 576673 c.1326G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 576675 p.Arg443His missense_variant 0.86 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576679 c.1332G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 576685 c.1338C>T synonymous_variant 0.73 ethionamide
isoniazid
mshA 576760 p.His471Gln missense_variant 0.79 ethionamide
isoniazid
ccsA 619696 c.-195C>T upstream_gene_variant 0.86 capreomycin
amikacin
ccsA 619697 c.-194_-192delAGGinsCGA upstream_gene_variant 0.87 capreomycin
amikacin
ccsA 619706 c.-185_-183delGTGinsATC upstream_gene_variant 0.95 capreomycin
amikacin
ccsA 619713 c.-178_-177delCGinsTT upstream_gene_variant 0.86 capreomycin
amikacin
ccsA 619725 c.-166C>T upstream_gene_variant 0.73 capreomycin
amikacin
ccsA 619726 c.-164delA upstream_gene_variant 0.95 capreomycin
amikacin
ccsA 619729 c.-162G>T upstream_gene_variant 0.9 capreomycin
amikacin
ccsA 619730 c.-161_-159delACCinsCCA upstream_gene_variant 0.89 capreomycin
amikacin
ccsA 619735 c.-156G>A upstream_gene_variant 0.88 capreomycin
amikacin
ccsA 619744 c.-147A>G upstream_gene_variant 0.92 capreomycin
amikacin
ccsA 619762 c.-129C>G upstream_gene_variant 0.8 capreomycin
amikacin
ccsA 619766 c.-125_-123delACGinsGCC upstream_gene_variant 0.9 capreomycin
amikacin
ccsA 619771 c.-120C>T upstream_gene_variant 0.8 capreomycin
amikacin
ccsA 619786 c.-105G>C upstream_gene_variant 0.9 capreomycin
amikacin
ccsA 619794 c.-97_-96delCCinsAT upstream_gene_variant 0.93 capreomycin
amikacin
ccsA 619805 c.-86_-85delCGinsAA upstream_gene_variant 0.9 capreomycin
amikacin
ccsA 619813 c.-78C>G upstream_gene_variant 0.8 capreomycin
amikacin
ccsA 619815 c.-76G>A upstream_gene_variant 0.73 capreomycin
amikacin
ccsA 619827 c.-64C>A upstream_gene_variant 0.81 capreomycin
amikacin
ccsA 619831 c.-60T>C upstream_gene_variant 0.87 capreomycin
amikacin
ccsA 619845 c.-46C>A upstream_gene_variant 0.81 capreomycin
amikacin
ccsA 619891 c.1T>G start_lost 0.83 capreomycin
amikacin
ccsA 619896 c.6C>T synonymous_variant 0.82 capreomycin
amikacin
ccsA 619899 c.9G>C synonymous_variant 0.74 capreomycin
amikacin
ccsA 619900 p.Leu4Glu missense_variant 0.82 capreomycin
amikacin
ccsA 619906 p.Val6Ile missense_variant 0.83 capreomycin
amikacin
ccsA 619909 p.Asn7Asp missense_variant 0.84 capreomycin
amikacin
ccsA 619912 p.Val8Ile missense_variant 0.83 capreomycin
amikacin
ccsA 619917 c.27C>G synonymous_variant 0.82 capreomycin
amikacin
ccsA 619920 c.30G>T synonymous_variant 0.85 capreomycin
amikacin
ccsA 619924 c.34_36delCGCinsAGG synonymous_variant 0.89 capreomycin
amikacin
ccsA 619947 c.57C>G synonymous_variant 0.87 capreomycin
amikacin
ccsA 619962 c.72G>C synonymous_variant 0.84 capreomycin
amikacin
ccsA 619970 p.Val27Gly missense_variant 0.81 capreomycin
amikacin
ccsA 619978 p.Leu30Ile missense_variant 0.84 capreomycin
amikacin
ccsA 619986 c.96G>C synonymous_variant 0.74 capreomycin
amikacin
ccsA 619989 c.99G>C synonymous_variant 0.82 capreomycin
amikacin
ccsA 619990 p.Phe34Val missense_variant 0.91 capreomycin
amikacin
ccsA 619995 c.105G>A synonymous_variant 0.91 capreomycin
amikacin
ccsA 619996 p.Phe36Leu missense_variant 0.78 capreomycin
amikacin
ccsA 620013 c.123T>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620018 p.Gly43Glu missense_variant 0.78 capreomycin
amikacin
ccsA 620020 p.Leu44Val missense_variant 0.74 capreomycin
amikacin
ccsA 620033 p.Ala48Val missense_variant 0.8 capreomycin
amikacin Uncertain significance
ccsA 620035 c.146delT frameshift_variant 0.92 capreomycin
amikacin
ccsA 620038 c.148_149insG frameshift_variant 0.9 capreomycin
amikacin
ccsA 620041 p.Ala51Thr missense_variant 0.84 capreomycin
amikacin
ccsA 620044 c.155_156delGA frameshift_variant 0.95 capreomycin
amikacin
ccsA 620052 c.163_166delGCCA frameshift_variant 0.94 capreomycin
amikacin
ccsA 620061 c.171T>C synonymous_variant 0.82 capreomycin
amikacin
ccsA 620064 c.174C>T synonymous_variant 0.81 capreomycin
amikacin
ccsA 620066 p.Ala59Val missense_variant 0.74 capreomycin
amikacin
ccsA 620076 c.186G>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620077 p.Ile63Val missense_variant 0.94 capreomycin Uncertain significance
amikacin Uncertain significance
ccsA 620082 c.192G>C synonymous_variant 0.87 capreomycin
amikacin
ccsA 620085 c.195G>C synonymous_variant 0.78 capreomycin
amikacin
ccsA 620088 p.Asp66Glu missense_variant 0.81 capreomycin
amikacin
ccsA 620089 p.Gln67Glu missense_variant 0.77 capreomycin
amikacin
ccsA 620100 c.210G>C synonymous_variant 0.73 capreomycin
amikacin
ccsA 620112 c.222A>G synonymous_variant 0.85 capreomycin
amikacin
ccsA 620115 c.225C>G synonymous_variant 0.89 capreomycin
amikacin
ccsA 620123 p.Arg78Gln missense_variant 0.89 capreomycin
amikacin
ccsA 620125 p.Gly79Thr missense_variant 0.77 capreomycin
amikacin
ccsA 620136 c.246C>G synonymous_variant 0.79 capreomycin
amikacin
ccsA 620137 p.Val83Leu missense_variant 0.86 capreomycin
amikacin
ccsA 620140 p.Ala84Thr missense_variant 0.87 capreomycin
amikacin
ccsA 620145 c.255T>C synonymous_variant 0.84 capreomycin
amikacin
ccsA 620146 p.Leu86Val missense_variant 0.75 capreomycin
amikacin
ccsA 620157 c.267G>C synonymous_variant 0.82 capreomycin
amikacin
ccsA 620158 p.Leu90Met missense_variant 0.91 capreomycin
amikacin
ccsA 620161 c.271C>T synonymous_variant 0.92 capreomycin
amikacin
ccsA 620164 p.Leu92Phe missense_variant 0.85 capreomycin
amikacin
ccsA 620168 p.Ala93Val missense_variant 0.83 capreomycin
amikacin
ccsA 620173 p.Val95Ile missense_variant 0.91 capreomycin
amikacin
ccsA 620179 c.289C>T synonymous_variant 0.93 capreomycin
amikacin
ccsA 620196 c.306C>G synonymous_variant 0.88 capreomycin
amikacin
ccsA 620197 p.Gln103Ser missense_variant 0.88 capreomycin
amikacin
ccsA 620242 p.Cys118Ser missense_variant 0.93 capreomycin
amikacin
ccsA 620247 p.Leu119Phe missense_variant 0.91 capreomycin
amikacin Uncertain significance
ccsA 620249 p.Ser120Cys missense_variant 0.88 capreomycin
amikacin Uncertain significance
ccsA 620253 c.363G>C synonymous_variant 0.89 capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 0.93 capreomycin
amikacin
ccsA 620264 p.Gly125Ala missense_variant 0.91 capreomycin
amikacin
ccsA 620282 p.Arg131His missense_variant 0.77 capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.74 capreomycin
amikacin Uncertain significance
ccsA 620288 p.Arg133Gln missense_variant 0.71 capreomycin
amikacin Uncertain significance
ccsA 620296 p.Pro136Ala missense_variant 0.83 capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.86 capreomycin
amikacin
ccsA 620311 p.Leu141Val missense_variant 0.9 capreomycin
amikacin Uncertain significance
ccsA 620319 c.429C>T synonymous_variant 0.9 capreomycin
amikacin
ccsA 620337 c.447C>G synonymous_variant 0.93 capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.89 capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.8 capreomycin
amikacin
ccsA 620349 c.459A>T synonymous_variant 0.93 capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 0.87 capreomycin
amikacin
ccsA 620362 p.Ala158Ser missense_variant 0.89 capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.96 capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.77 capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620385 c.495G>T synonymous_variant 0.87 capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.94 capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.89 capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.96 capreomycin
amikacin
ccsA 620421 c.531G>C synonymous_variant 0.87 capreomycin
amikacin
ccsA 620427 c.537C>G synonymous_variant 0.91 capreomycin
amikacin
ccsA 620436 c.546T>C synonymous_variant 0.76 capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.94 capreomycin
amikacin
ccsA 620463 c.573C>G synonymous_variant 0.94 capreomycin
amikacin
ccsA 620481 c.591T>G synonymous_variant 0.85 capreomycin
amikacin
ccsA 620482 p.Val198Leu missense_variant 0.91 capreomycin
amikacin Uncertain significance
ccsA 620485 p.Arg199Lys missense_variant 0.9 capreomycin
amikacin
ccsA 620489 p.Thr200Met missense_variant 0.89 capreomycin
amikacin
ccsA 620495 p.Arg202Pro missense_variant 0.95 capreomycin
amikacin Uncertain significance
ccsA 620502 c.612T>C synonymous_variant 0.95 capreomycin
amikacin
ccsA 620509 p.Thr207Ala missense_variant 0.77 capreomycin
amikacin
ccsA 620523 c.633G>C synonymous_variant 0.73 capreomycin
amikacin
ccsA 620524 p.Leu212Val missense_variant 0.74 capreomycin
amikacin
ccsA 620532 c.642T>G synonymous_variant 0.94 capreomycin
amikacin
ccsA 620535 p.Met215Ile missense_variant 0.91 capreomycin
amikacin
ccsA 620536 p.Val216Met missense_variant 0.78 capreomycin
amikacin
ccsA 620537 c.648delG frameshift_variant 0.96 capreomycin
amikacin
ccsA 620547 c.657C>G synonymous_variant 0.83 capreomycin
amikacin
ccsA 620553 c.663T>C synonymous_variant 0.95 capreomycin
amikacin
ccsA 620556 c.666C>G synonymous_variant 0.88 capreomycin
amikacin
ccsA 620559 c.669A>G synonymous_variant 0.88 capreomycin
amikacin
ccsA 620562 c.672C>G synonymous_variant 0.92 capreomycin
amikacin
ccsA 620569 p.Gly227Arg missense_variant 0.77 capreomycin
amikacin Uncertain significance
ccsA 620574 c.684C>T synonymous_variant 0.86 capreomycin
amikacin
ccsA 620583 c.693G>C synonymous_variant 0.92 capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 0.89 capreomycin
amikacin
ccsA 620605 p.Val239Ile missense_variant 0.77 capreomycin
amikacin Uncertain significance
ccsA 620613 c.723C>T synonymous_variant 0.88 capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 0.91 capreomycin
amikacin
ccsA 620634 c.744C>G synonymous_variant 0.93 capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.9 capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 0.94 capreomycin
amikacin
ccsA 620670 c.780C>T synonymous_variant 0.92 capreomycin
amikacin
ccsA 620676 c.786C>T synonymous_variant 0.84 capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.91 capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.93 capreomycin
amikacin Uncertain significance
ccsA 620703 c.813G>C synonymous_variant 0.95 capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.9 capreomycin
amikacin
ccsA 620724 c.834C>T synonymous_variant 0.92 capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.74 capreomycin
amikacin
ccsA 620736 c.846G>C synonymous_variant 0.81 capreomycin
amikacin