Run ID: ERR4811105
Sample name:
Date: 2024-04-16T12:32:21.435538
Number of reads: 2440453
Percentage reads mapped: 26.95
Median coverage: 101.0
Strain: La3;lineage2.1;lineage4.9;lineage6.3
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage1.2.2 | Indo-Oceanic | RD239 | 0.12 |
| lineage6.2.2 | West-Africa 2 | RD702 | 0.1 |
| lineage6.1.1 | West-Africa 2 | RD702 | 0.18 |
| lineage6.3 | West-Africa 2 | RD702 | 0.14 |
| lineage4.6.2.2 | Euro-American (Cameroon) | RD726 | 0.23 |
| lineage4.1.2.1.1 | Euro-American (Haarlem) | RD182 | 0.24 |
| La1.2.BCG | M.bovis | None | 0.41 |
| lineage2.1 | East-Asian (non-Beijing) | None | 0.29 |
| lineage1.1.1 | Indo-Oceanic | RD239 | 0.13 |
| lineage6.2.3 | West-Africa 2 | RD702 | 0.33 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.56 |
| La1.7.1 | M.bovis | None | 0.13 |
| La3 | M.orygis | None | 0.45 |
| lineage4.6.2.1 | Euro-American | RD726 | 0.11 |
| lineage6.2.1 | West-Africa 2 | RD702 | 0.34 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | p.Ile335Thr | Mutation from literature | |
| p.Ile317Leu | Mutation from literature | |||
| c.922_924delACCinsTG | Assoc w R | High-level resistance | ||
| ethambutol | embB | p.His312Arg | Mutation from literature | |
| p.Tyr384Asn | Mutation from literature | |||
| p.Ala388Gly | Mutation from literature | |||
| p.Asn399Asp | Mutation from literature | |||
| pyrazinamide | panD | p.Val138Ala | Mutation from literature | |
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | tlyA | c.4_6delGCAinsTT | Assoc w R | |
| c.172_174delAGTinsGC | Assoc w R | |||
| c.238_240delGCGinsTC | Assoc w R | |||
| c.319_321delCACinsGA | Assoc w R | |||
| c.376_378delCCTinsGG | Assoc w R | |||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | pepQ | c.520_522delCGCinsAG | Assoc w R - Interim | |
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.202_204delCTGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.412_414delCTAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.718_720delGAGinsAA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.730_732delAACinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiC | c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2224_2226delTTGinsCA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiA | c.358_360delCAGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.772_774delACGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | pepQ | c.520_522delCGCinsAG | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV |
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 490984 | c.202_204delCTGinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491194 | c.412_414delCTAinsTG | frameshift_variant&stop_gained | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491500 | c.718_720delGAGinsAA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491512 | c.730_732delAACinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 0.99 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305154 | c.2224_2226delTTGinsCA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| tlyA | 1917943 | c.4_6delGCAinsTT | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
| tlyA | 1918111 | c.172_174delAGTinsGC | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
| tlyA | 1918177 | c.238_240delGCGinsTC | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
| tlyA | 1918258 | c.319_321delCACinsGA | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
| tlyA | 1918315 | c.376_378delCCTinsGG | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
| katG | 2155107 | p.Ile335Thr | missense_variant | 1.0 | isoniazid | Mutation from literature | |
| katG | 2155163 | p.Ile317Leu | missense_variant | 1.0 | isoniazid | Mutation from literature | |
| katG | 2155188 | c.922_924delACCinsTG | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
| pepQ | 2859897 | c.520_522delCGCinsAG | frameshift_variant&missense_variant | 1.0 | bedaquiline | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV |
| clofazimine | Assoc w R - Interim | ||||||
| fbiA | 3640900 | c.358_360delCAGinsAC | frameshift_variant&missense_variant | 0.98 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiA | 3641314 | c.772_774delACGinsGC | frameshift_variant&missense_variant | 0.96 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| panD | 4043869 | p.Val138Ala | missense_variant | 1.0 | pyrazinamide | Mutation from literature | |
| embB | 4247448 | p.His312Arg | missense_variant | 1.0 | ethambutol | Mutation from literature | |
| embB | 4247663 | p.Tyr384Asn | missense_variant | 1.0 | ethambutol | Mutation from literature | |
| embB | 4247676 | p.Ala388Gly | missense_variant | 1.0 | ethambutol | Mutation from literature | |
| embB | 4247708 | p.Asn399Asp | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 30 | c.30C>G | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 42 | c.42C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 51 | c.51C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 57 | c.57A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 60 | c.60T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 504 | c.504T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 510 | c.510T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 519 | c.519C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
| dnaA | 522 | c.522T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 525 | c.525T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 534 | c.534T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 558 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 561 | c.561C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 567 | c.567C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 571 | c.571T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 582 | c.582A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 585 | c.585A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 588 | c.588A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 591 | c.591C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 600 | c.600T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 627 | c.627G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 645 | c.645A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 649 | c.649C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 654 | c.654A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 660 | c.660G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 663 | c.663A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 669 | c.669C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 672 | c.672T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 675 | c.675C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 678 | c.678A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 681 | c.681G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 682 | c.682T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 693 | c.693A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 705 | c.705A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 768 | c.768C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 771 | c.771A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 777 | c.777A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 786 | c.786C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 792 | c.792C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 795 | c.795A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 805 | c.805_807delTTGinsCC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 813 | c.813C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 819 | c.819C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 837 | c.837A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 876 | c.876C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 877 | c.877T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 909 | c.909A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 912 | c.912T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 918 | c.918C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 921 | c.921A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 942 | c.942C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 945 | c.945G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 955 | c.955A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 960 | c.960C>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 963 | c.963C>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 966 | c.966T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 969 | c.969G>A | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 975 | c.975G>T | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 984 | c.984T>C | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
| dnaA | 990 | c.990A>G | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
| dnaA | 993 | c.993A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 996 | c.996A>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
| dnaA | 999 | c.999C>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1008 | c.1008G>A | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
| dnaA | 1014 | c.1014C>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1024 | c.1024T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1038 | c.1038A>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1047 | c.1047A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
| dnaA | 1098 | c.1098A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1110 | c.1110T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1113 | c.1113A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1125 | c.1125G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1137 | c.1137C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1143 | c.1143G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1152 | c.1152A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1153 | c.1153T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1164 | c.1164A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1167 | c.1167A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1176 | c.1176A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1188 | c.1188G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1197 | c.1197T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1204 | c.1204C>T | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1220 | p.Asn407Ser | missense_variant | 0.99 | isoniazid | |
| dnaA | 1230 | c.1230A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1236 | c.1236C>T | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1242 | c.1242G>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1245 | c.1245G>C | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
| dnaA | 1254 | c.1254T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1278 | c.1278T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1284 | c.1284C>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1290 | c.1290G>A | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1293 | c.1293T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1299 | c.1299G>C | synonymous_variant | 0.98 | isoniazid | Not assoc w R - Interim |
| dnaA | 1302 | c.1302C>G | synonymous_variant | 0.98 | isoniazid | |
| dnaA | 1311 | c.1311C>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1314 | c.1314A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1317 | c.1317A>G | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1320 | c.1320G>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1332 | c.1332A>C | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
| dnaA | 1338 | c.1338T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1353 | c.1353T>C | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1371 | c.1371T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1375 | c.1375T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1383 | c.1383A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1389 | c.1389C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1392 | c.1392A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1395 | c.1395G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1404 | c.1404T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1407 | c.1407T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1416 | c.1416C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1428 | c.1428C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1449 | c.1449G>A | synonymous_variant | 0.99 | isoniazid | |
| dnaA | 1461 | c.1461C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1470 | c.1470C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1485 | c.1485A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1488 | c.1488A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1497 | c.1497T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1506 | c.1506T>G | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 5809 | c.570C>G | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5812 | c.573C>G | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5824 | c.585A>G | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5827 | c.588G>A | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5849 | c.610C>T | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5863 | c.624G>C | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6082 | c.843G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6086 | p.Thr283Pro | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6091 | c.852G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6123 | p.Ala295Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6136 | c.897G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6139 | c.900G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6238 | c.999G>A | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6242 | p.Arg335Lys | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6256 | c.1017G>A | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6268 | c.1029C>G | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6289 | c.1050C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6415 | c.-887G>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6427 | c.-875T>C | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6430 | c.-872A>G | upstream_gene_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6440 | c.1201_1203delACCinsGG | frameshift_variant&missense_variant | 0.97 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6448 | c.-854G>C | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6451 | c.-851A>G | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6454 | c.-848C>G | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6457 | c.-845T>G | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6460 | c.-842G>C | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6469 | c.-833T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6475 | c.-827C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6484 | c.-818A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6490 | c.-812T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6496 | c.-806G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6499 | c.-803A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6502 | c.-800T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6508 | c.-794A>G | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6523 | c.-779G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6526 | c.-776T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6541 | c.1302C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6542 | c.1303_1305delATCinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6547 | c.-755T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6550 | c.1311A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6551 | c.1312T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6565 | c.-737G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6568 | c.-734C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6571 | c.-731T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6577 | c.1338T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6580 | c.-722C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6598 | c.-704C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6646 | c.-656C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6680 | c.1441C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6763 | c.1524G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6775 | c.1536G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Thr | missense_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6811 | c.1572C>T | synonymous_variant | 0.99 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642_1644delTTGinsCC | frameshift_variant&missense_variant | 0.99 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6889 | c.-413G>T | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6901 | c.-401G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6910 | c.-392G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6916 | c.-386G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6919 | c.1680T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6931 | c.1692A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.99 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7015 | p.Glu592Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7075 | c.-227T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7093 | c.-209T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7114 | c.-188C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7124 | c.1885_1887delTCGinsAC | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7165 | c.-137C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7186 | c.1947C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7216 | c.1977G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 7234 | c.1995C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7246 | c.2007T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7252 | c.-50G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7256 | c.2017_2019delCTGinsTA | frameshift_variant&stop_gained | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7301 | c.-1G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7307 | c.6A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7313 | c.12G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7317 | c.16T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7324 | c.23_24insAGG | disruptive_inframe_insertion | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7334 | c.33G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7335 | p.Leu12Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7347 | c.46_48delGAAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7361 | c.60C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7424 | c.123G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7505 | c.204C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7625 | c.324G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7626 | c.325C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7775 | c.474C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7781 | c.480G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7790 | c.489G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7823 | c.522G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7853 | c.552C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7859 | c.558A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7886 | c.585T>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8051 | c.750C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8054 | c.753T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8057 | c.756A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8069 | c.768T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8078 | c.777A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8090 | c.789C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8096 | c.795T>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8099 | c.798T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8111 | c.810G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8121 | c.820T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8129 | c.828T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8135 | c.834C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8234 | c.933T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8247 | c.946_948delATCinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8270 | c.969G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8276 | c.975G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8330 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8372 | c.1071G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8387 | c.1086C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8401 | p.Asp367Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8405 | c.1104C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8442 | c.1141C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8465 | c.1164C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8472 | c.1171C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8528 | c.1227G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8543 | c.1242C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8552 | c.1251C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8576 | c.1275C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8579 | c.1278C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8597 | c.1296C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8619 | c.1318_1320delTTGinsCA | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8696 | c.1395G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8730 | p.Gly477Arg | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 8740 | p.Arg480His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8750 | c.1449C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8751 | p.Ala484Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8780 | p.Asp493Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8807 | c.1506C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8816 | c.1515C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8837 | c.1536C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8918 | c.1617C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8933 | c.1632G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8967 | p.Ala556Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9017 | c.1716C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9035 | c.1734G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9122 | c.1821C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9152 | c.1851C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9153 | p.Thr618Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9158 | c.1857C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9161 | c.1860C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9191 | c.1890G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9224 | c.1923C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9239 | c.1938C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9291 | c.1990C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9299 | c.1998G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9300 | p.Ala667Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 0.99 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9365 | c.2064G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9374 | c.2073G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9398 | c.2097T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9413 | c.2112G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9419 | c.2118T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9566 | c.2265C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9572 | c.2271C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9578 | c.2277C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9582 | c.2281A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9585 | c.2284T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9590 | c.2289T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9593 | c.2292G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9602 | c.2301T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9611 | p.Asp770Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9626 | c.2325T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9629 | c.2328C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9630 | p.Val777Ile | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9638 | c.2337C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9641 | c.2340C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9644 | c.2343T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9650 | c.2349G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9656 | c.2355C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9665 | c.2364A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9666 | p.Arg789Gly | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9674 | c.2373T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9704 | c.2403T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9708 | c.2407T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9716 | c.2415T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9725 | c.2424G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9727 | p.Gly809Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9729 | p.Asp810Asn | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9734 | c.2433A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| Rv0010c | 13852 | c.-296_-294delTTAinsCG | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13860 | c.-302A>G | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13864 | c.-306A>G | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13876 | c.-318G>C | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13879 | c.-321T>C | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13890 | c.-332T>C | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13893 | c.-335T>G | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13897 | c.-339C>T | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 1.0 | isoniazid | |
| fgd1 | 490555 | c.-228G>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490782 | c.-1G>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490797 | c.15G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490800 | c.18A>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 490803 | c.21T>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490812 | c.30A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490815 | c.33G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490827 | c.45C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490848 | c.66A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 490851 | c.69A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490868 | p.Ala29Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490887 | c.105G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490890 | c.108C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490896 | c.114C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490911 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490917 | c.135C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490929 | c.147C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490935 | c.153C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490962 | c.180T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490974 | c.192T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490977 | c.195C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490980 | p.Asn66Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490987 | p.Leu69Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490998 | c.216T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491001 | c.219G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491077 | p.Asn99Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491082 | c.300T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491091 | c.309T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491094 | c.312C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491097 | c.315G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491100 | c.318C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491130 | c.348C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491151 | c.369G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491173 | c.391C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491184 | c.402A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491289 | c.507C>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491292 | c.510G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 0.99 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491302 | p.Ile174Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491307 | c.525C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491313 | c.531C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491319 | c.537G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491325 | c.543G>C | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491337 | c.555C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491340 | c.558C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491367 | c.585G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491453 | p.Gly224Asp | missense_variant | 1.0 | clofazimine | Uncertain significance |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fgd1 | 491472 | c.690A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491487 | c.705C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491496 | c.714C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491499 | c.717G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491535 | c.753G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491553 | c.771G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491643 | c.861G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491646 | c.864G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491649 | c.867C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491661 | c.879C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491673 | c.891A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491676 | c.894T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491679 | c.897A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491687 | p.Thr302Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491697 | c.915G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491709 | c.927A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491712 | c.930T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491718 | c.936A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491721 | c.939A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491724 | c.942A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491727 | c.945T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491748 | p.Glu322Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 574595 | c.-753A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574604 | c.-744C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574607 | c.-741G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574616 | c.-732G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574619 | c.-729C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574640 | c.-708G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574650 | c.-698A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574655 | c.-693C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574664 | c.-684G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574671 | c.-677_-675delGCAinsCTG | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574676 | c.-672G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574683 | c.-665T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574688 | c.-660G>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 574694 | c.-654C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574712 | c.-636A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574718 | c.-630A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574724 | c.-624T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574731 | c.-617A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574739 | c.-609T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574758 | c.-590G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574970 | c.-378A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574979 | c.-369G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574985 | c.-363G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574988 | c.-360G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574996 | c.-352C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575000 | c.-348C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575009 | c.-339T>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575011 | c.-337G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575018 | c.-330C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575022 | c.-326C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575030 | c.-318T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575034 | c.-314_-312delTTAinsAG | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575042 | c.-306T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575052 | c.-296G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575057 | c.-291G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575060 | c.-288G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575063 | c.-285T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575075 | c.-273T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 575084 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575117 | c.-231T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575118 | c.-230_-228delACGinsGC | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575124 | c.-224_-222delGGGinsCC | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575137 | c.-211C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575144 | c.-204T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575154 | c.-194_-192delGTGinsCC | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575161 | c.-187_-186delTTinsCG | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575536 | c.189T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575542 | c.195C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575561 | p.Met72Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575569 | c.222A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575571 | p.Ser75Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575576 | c.229C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575581 | c.234C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575587 | c.240C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575590 | c.243T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575623 | c.276C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575629 | c.282A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575632 | c.285G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575635 | c.288A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575638 | c.291T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575641 | c.294A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575649 | p.Val101Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575662 | c.315C>G | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575665 | c.318G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575674 | c.327G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575701 | c.354G>A | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575704 | c.357T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575752 | c.405G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575755 | c.408G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575770 | c.423G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575809 | c.462C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575812 | c.465C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 0.99 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575830 | c.483C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575833 | c.486C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575845 | c.498C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575884 | c.537G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575887 | c.540G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575917 | p.Asp190Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575920 | c.573C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575924 | p.Gly193Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575950 | c.603C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575965 | c.618C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575977 | c.630G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575980 | c.633T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575984 | c.637T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576004 | c.657T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576007 | c.660A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576163 | c.816A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576166 | c.819C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576184 | c.837A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576193 | c.846T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576197 | c.850C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576205 | c.858G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 576208 | c.861C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576211 | c.864C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576214 | c.867G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576215 | c.868T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576229 | c.882C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576233 | p.Ile296Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576241 | c.894C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576262 | c.915T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576271 | c.924A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576281 | c.934C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 576285 | p.Val313Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576289 | c.942G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576292 | c.945C>G | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| mshA | 576301 | c.954A>G | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619507 | c.-384A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619528 | c.-363C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619531 | c.-360T>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619543 | c.-348C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619552 | c.-339A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619609 | c.-282G>C | upstream_gene_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619634 | c.-257T>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619645 | c.-246G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619654 | c.-237A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619668 | c.-223_-222delCGinsGC | upstream_gene_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619672 | c.-219A>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619676 | c.-215C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619697 | c.-194_-192delAGGinsCC | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619705 | c.-186G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620196 | c.306C>G | synonymous_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620197 | p.Gln103Val | missense_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620226 | c.336G>A | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620265 | c.375C>G | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620268 | c.378G>C | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | c.394_396delGCGinsCC | frameshift_variant&missense_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620295 | c.405G>T | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620298 | c.408G>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620310 | c.420C>T | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620346 | c.456C>G | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620376 | c.486G>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620389 | c.499C>T | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 0.98 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620421 | c.531G>C | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620424 | c.534G>C | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620433 | c.543C>G | synonymous_variant | 0.97 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620436 | c.546T>A | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620439 | c.549T>C | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620460 | c.570T>G | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620461 | p.Val191Ile | missense_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620481 | c.591T>G | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620482 | p.Val198Leu | missense_variant | 0.93 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620490 | c.600A>C | synonymous_variant | 0.92 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620569 | c.679_681delGGAinsCC | frameshift_variant&missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620583 | c.693G>C | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620586 | c.696C>G | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620598 | c.708C>G | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620601 | c.711C>T | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620607 | c.717T>C | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620613 | c.723C>G | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620622 | c.732G>C | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620631 | c.741T>G | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620646 | c.756G>A | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620659 | c.769_771delCGCinsAG | frameshift_variant&missense_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620664 | c.774C>T | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620682 | c.792G>A | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620688 | c.798G>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620710 | c.820_822delGTGinsAA | frameshift_variant&missense_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620742 | c.852G>C | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620745 | c.855G>C | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>A | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620763 | c.873G>A | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620769 | c.879C>G | synonymous_variant | 0.99 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 0.99 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620784 | c.894C>G | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620790 | c.900C>T | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620796 | c.906C>G | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620809 | c.919C>T | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620823 | c.933C>T | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620832 | c.942C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| Rv0565c | 656166 | c.1305C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656172 | c.1299A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656179 | p.Asp431Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656192 | p.Asp427Asn | missense_variant | 0.98 | ethionamide | Uncertain significance |
| Rv0565c | 656196 | p.Leu425Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656219 | p.His418Tyr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656220 | c.1251A>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656223 | c.1248T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656226 | c.1243_1245delGCCinsTT | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656238 | p.Ala411Glu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656243 | p.Leu410Met | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656244 | c.1227A>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656265 | c.1206G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656268 | p.Met401Ile | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656277 | c.1194C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656289 | c.1182C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656298 | c.1173G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656304 | c.1167T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656325 | c.1146C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656358 | c.1113T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656361 | c.1110C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656364 | c.1107T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656367 | c.1101_1104delTCGGinsGC | frameshift_variant&synonymous_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656371 | p.Pro367His | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656375 | c.1095_1096insAA | frameshift_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656383 | p.Val363Asn | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656391 | c.1080C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656402 | p.Ala357Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656412 | c.1059T>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656418 | c.1053A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656423 | c.1048T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656448 | c.1021_1023delATTinsGC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656454 | c.1017G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656457 | c.1014T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656469 | c.1002T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656475 | c.996A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656484 | c.987T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656487 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656493 | c.978C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656502 | c.969C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656511 | c.960T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656526 | p.Glu315Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656535 | c.936C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656539 | p.Ser311Ala | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656542 | p.Thr310Ser | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656550 | c.919_921delAACinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656568 | c.903G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656582 | p.Leu297Met | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656583 | c.888A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656589 | c.882T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656595 | c.876G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656611 | p.Thr287Lys | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656892 | c.579C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656901 | c.570C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656904 | c.567G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656924 | p.Ile183Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656936 | p.Thr179Ala | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656940 | c.531C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656946 | c.525T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656952 | c.519A>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656967 | c.504T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656973 | c.498A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656978 | p.Ala165Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656982 | p.Gly163Gln | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656985 | c.486T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656990 | p.Lys161Glu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657000 | p.Gly157Pro | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657027 | c.444T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657056 | p.Val139Leu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657060 | c.411G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657065 | p.Ser136Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657073 | p.His133Leu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657076 | p.Lys132Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657079 | p.His131Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657082 | p.Val130Glu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657084 | c.387C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657088 | p.Asn128Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657093 | c.378G>A | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657098 | p.Phe125Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657105 | c.366C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657114 | c.357T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 657120 | c.349_351delTCCinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657123 | c.348A>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657138 | c.331_333delGCAinsTG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657144 | c.327T>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657155 | p.Asn106Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657160 | p.Glu104Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657171 | c.300T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657187 | p.His95Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657189 | c.282C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657192 | p.Met93Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657196 | p.Asp92Ala | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657200 | p.Thr91Ala | missense_variant | 0.97 | ethionamide | Uncertain significance |
| Rv0565c | 657201 | c.270C>G | synonymous_variant | 0.97 | ethionamide | |
| Rv0565c | 657219 | p.Ala84Val | missense_variant | 0.97 | ethionamide | |
| Rv0565c | 657231 | c.238_240delATCinsGG | frameshift_variant&missense_variant | 0.98 | ethionamide | Uncertain significance |
| Rv0565c | 657237 | c.234A>G | synonymous_variant | 0.98 | ethionamide | |
| Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.99 | ethionamide | |
| Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657327 | c.144C>G | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657337 | p.Arg45Gln | missense_variant | 0.98 | ethionamide | Uncertain significance |
| Rv0565c | 657342 | c.129T>C | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657347 | c.124A>C | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657348 | c.123A>G | synonymous_variant | 0.99 | ethionamide | |
| Rv0565c | 657356 | p.Ile39Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657372 | c.99G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657375 | c.96C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657385 | p.Ile29Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657399 | c.72G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657403 | p.Gly23Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657405 | c.64_66delCTGinsAT | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657408 | c.63A>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657434 | p.Val13Ile | missense_variant | 0.95 | ethionamide | |
| Rv0565c | 657560 | c.-90G>C | upstream_gene_variant | 0.96 | ethionamide | |
| Rv0565c | 657563 | c.-93T>C | upstream_gene_variant | 0.96 | ethionamide | |
| Rv0565c | 657571 | c.-101T>C | upstream_gene_variant | 0.97 | ethionamide | |
| Rv0565c | 657572 | c.-102A>G | upstream_gene_variant | 0.97 | ethionamide | |
| Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657592 | c.-122A>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657600 | c.-132_-131delCA | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657606 | c.-136T>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657607 | c.-138_-137insCA | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731682 | c.-248C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731687 | c.-243_-242insCACAGATCTTTT | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731693 | c.-237C>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731696 | c.-233_-232delTT | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731708 | c.-222G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731710 | c.-220A>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731711 | c.-219T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731717 | c.-213T>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731732 | c.-198G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.98 | isoniazid | |
| hadA | 731792 | c.-138G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731801 | c.-129C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731816 | c.-114G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731840 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731843 | c.-87T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731849 | c.-81C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731852 | c.-78A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731864 | c.-66C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 732238 | c.309G>C | synonymous_variant | 0.95 | isoniazid | |
| hadA | 732253 | c.324T>C | synonymous_variant | 0.96 | isoniazid | |
| hadA | 732259 | c.330T>C | synonymous_variant | 0.96 | isoniazid | |
| hadA | 732268 | c.339T>G | synonymous_variant | 0.96 | isoniazid | |
| hadA | 732270 | p.Glu114Val | missense_variant | 0.96 | isoniazid | |
| hadA | 732272 | p.Ala115Ser | missense_variant | 0.96 | isoniazid | |
| hadA | 732295 | c.366G>C | synonymous_variant | 0.97 | isoniazid | |
| hadA | 732305 | p.Ile126Val | missense_variant | 0.97 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 0.96 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 0.98 | isoniazid | |
| hadA | 732329 | p.Leu134Val | missense_variant | 0.98 | isoniazid | Uncertain significance |
| hadA | 732337 | c.408G>A | synonymous_variant | 0.98 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.98 | isoniazid | |
| hadA | 732396 | p.Gly156Ala | missense_variant | 0.99 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 0.99 | isoniazid | |
| nusG | 734078 | c.-176C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734093 | c.-161A>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734102 | c.-152G>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734111 | c.-143A>G | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734114 | c.-140A>G | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.97 | rifampicin | Uncertain significance |
| nusG | 734123 | c.-131C>G | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734132 | c.-122G>C | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734135 | c.-119G>C | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734144 | c.-110G>C | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734173 | c.-81C>G | upstream_gene_variant | 0.98 | rifampicin | |
| nusG | 734175 | c.-79_-77delGGTinsCTG | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734180 | c.-74T>G | upstream_gene_variant | 0.95 | rifampicin | Uncertain significance |
| nusG | 734183 | c.-71C>T | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734186 | c.-68G>C | upstream_gene_variant | 0.98 | rifampicin | Uncertain significance |
| nusG | 734205 | c.-49A>C | upstream_gene_variant | 0.97 | rifampicin | |
| nusG | 734223 | c.-30_-28delGCT | upstream_gene_variant | 0.9 | rifampicin | |
| nusG | 734230 | c.-24_-23insCGACGCCGCTGTGAAA | upstream_gene_variant | 0.9 | rifampicin | |
| nusG | 734247 | c.-7_-6delGAinsC | upstream_gene_variant | 0.8 | rifampicin | |
| nusG | 734250 | c.-4A>C | upstream_gene_variant | 0.82 | rifampicin | |
| nusG | 734261 | p.Thr3Ser | missense_variant | 0.82 | rifampicin | |
| nusG | 734275 | p.Thr8Pro | missense_variant | 0.9 | rifampicin | |
| nusG | 734340 | c.87T>C | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734352 | c.99T>C | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734360 | p.Ala36Val | missense_variant | 0.98 | rifampicin | Uncertain significance |
| nusG | 734370 | c.117A>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734376 | c.123G>A | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734457 | c.204C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734556 | c.303C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734601 | c.348C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734610 | c.357C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734625 | c.372T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734631 | c.378G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734634 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734637 | c.384G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734643 | c.390G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734652 | c.399T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734658 | c.405A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| nusG | 734661 | c.408A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734664 | c.411T>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734673 | c.420A>G | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734676 | c.423G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734679 | c.426C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734680 | c.427_429delGCCinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734703 | c.450T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734709 | c.456T>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734715 | c.462G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734718 | c.465G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734719 | p.Ser156Ala | missense_variant | 1.0 | rifampicin | |
| nusG | 734726 | p.Arg158Lys | missense_variant | 1.0 | rifampicin | |
| nusG | 734733 | c.480T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734742 | c.489T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734748 | c.495C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734750 | p.Ser166Thr | missense_variant | 1.0 | rifampicin | |
| nusG | 734754 | c.501G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734757 | c.504T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734758 | p.Ala169Thr | missense_variant | 0.97 | rifampicin | |
| nusG | 734772 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734775 | c.522C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734781 | c.528A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734784 | c.531G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734787 | c.534T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734792 | p.Val180Ala | missense_variant | 1.0 | rifampicin | |
| nusG | 734794 | p.Val181Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734814 | c.561G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734826 | c.573A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734829 | c.576C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734841 | c.588G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734850 | c.597C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734882 | p.Ala210Gly | missense_variant | 1.0 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734913 | c.660C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734931 | c.678A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734937 | c.684G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734940 | c.687G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734941 | c.688C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734949 | c.696T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734950 | p.Gly233Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 759587 | c.-220T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759606 | c.-201T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759629 | c.-178T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759644 | c.-163T>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759647 | c.-160T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759655 | c.-152C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759656 | c.-151A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759657 | c.-150G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759659 | c.-148T>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759660 | c.-147T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759662 | c.-145C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759667 | c.-140C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759670 | c.-137C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759671 | c.-136G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759672 | c.-135G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759683 | c.-124T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759701 | c.-106A>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759715 | c.-91delA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759725 | c.-82A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759728 | c.-78_-77delTA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 760040 | c.234T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760046 | c.240G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760060 | p.Tyr85Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760067 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760412 | c.606C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760715 | c.909C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760718 | c.912C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760751 | c.945G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760757 | c.951T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760759 | p.Val318Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760769 | c.963C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760775 | c.969G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760845 | p.Thr347Pro | missense_variant | 1.0 | rifampicin | |
| rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760869 | p.Val355Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761006 | c.1200C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761129 | c.1323G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761153 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761213 | c.1407G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761219 | c.1413G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761306 | c.1500C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761411 | c.1605G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761438 | c.1632G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761439 | c.1633_1635delGACinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761447 | c.1641C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761452 | p.Val549Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761457 | p.Pro551Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761465 | c.1659G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761477 | c.1671C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761531 | c.1725C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761588 | c.1782C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761720 | c.1914C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761815 | p.Ala670Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 0.99 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 0.99 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 0.99 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762206 | c.2400C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762246 | c.2440C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762410 | c.2604T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762413 | c.2607G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762419 | c.-951C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762467 | c.-903C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762488 | c.2682G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762489 | p.Val895Gln | missense_variant | 0.99 | rifampicin | |
| rpoC | 762512 | c.-858C>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 762521 | c.-849C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762581 | c.-789T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762582 | c.-788T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762729 | p.Gln975Lys | missense_variant | 1.0 | rifampicin | |
| rpoB | 762736 | p.Ala977Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 762743 | c.-627G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762744 | p.Gln980Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 762750 | p.Leu982Met | missense_variant | 1.0 | rifampicin | |
| rpoB | 762753 | c.2947T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762758 | c.-612G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762788 | c.2982G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762810 | c.3004_3006delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763013 | c.-357C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 763214 | c.3408T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.99 | rifampicin | |
| rpoB | 763227 | c.3421C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.98 | rifampicin | |
| rpoB | 763268 | c.3462C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 763283 | c.3477T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763284 | c.-86C>T | upstream_gene_variant | 0.97 | rifampicin | |
| rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.95 | rifampicin | Uncertain significance |
| rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.96 | rifampicin | Uncertain significance |
| rpoC | 763402 | c.33C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763411 | c.42T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763492 | c.123G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763657 | c.288G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763738 | c.369G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 763853 | p.Val162Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763945 | c.576T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763951 | c.582G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763960 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763987 | c.618C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764102 | p.Val245Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 764112 | p.Tyr248Phe | missense_variant | 1.0 | rifampicin | |
| rpoC | 764116 | c.747C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764215 | c.846A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764236 | c.867G>A | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764248 | c.879C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764353 | c.984G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.99 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764419 | c.1050C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764489 | c.1120C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764548 | c.1179G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764551 | c.1182G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765011 | c.1642_1643delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765055 | c.1686C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765292 | c.1923G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765298 | c.1929G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Ala | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 765404 | p.Leu679Val | missense_variant | 0.99 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765451 | c.2082C>A | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765559 | c.2190G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765580 | c.2211G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765613 | p.His748Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765947 | c.2578T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766054 | c.2685C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766082 | p.Ala905Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766096 | c.2727G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766135 | c.2766G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766142 | c.2773C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766174 | p.Asn935Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766178 | p.Ile937Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 766185 | p.Glu939Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766189 | c.2820T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766192 | c.2823T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766193 | c.2824_2826delCAAinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766204 | c.2835C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766207 | c.2838T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766216 | c.2847T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766219 | p.Asp950Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766222 | c.2853T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766226 | c.2857T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766231 | c.2862T>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 766234 | c.2865T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766237 | c.2868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766240 | c.2871T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766243 | c.2874C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766258 | c.2889T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766273 | c.2904T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766274 | p.Ala969Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766280 | p.Ser971Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766288 | c.2919C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766303 | c.2934C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766312 | c.2943T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766327 | c.2958C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766357 | c.2988C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766366 | c.2997C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766390 | c.3021C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766462 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766673 | p.Gly1102Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767014 | c.3645G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767264 | p.Ala1299Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767275 | c.3906T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767278 | c.3909T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767284 | c.3915C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767288 | c.3919C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775901 | c.2580G>A | synonymous_variant | 0.95 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775909 | p.Leu858Phe | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775913 | c.2568C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775916 | c.2565T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775921 | c.2560C>T | synonymous_variant | 0.86 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775937 | c.2542_2544delGCGinsTC | frameshift_variant&missense_variant | 0.63 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.62 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775946 | c.2535C>G | synonymous_variant | 0.43 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775955 | c.2524_2526delATCinsCG | frameshift_variant&missense_variant | 0.44 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.52 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.51 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775973 | c.2506_2508delTTGinsCC | frameshift_variant&missense_variant | 0.51 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775981 | p.Leu834Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775990 | c.2491C>T | synonymous_variant | 0.48 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775991 | c.2488_2490delGAGinsAA | frameshift_variant&synonymous_variant | 0.52 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775994 | c.2485_2487delATCinsTG | frameshift_variant&missense_variant | 0.48 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775997 | c.2484T>C | synonymous_variant | 0.52 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776000 | c.2479_2481delCTGinsAC | frameshift_variant&missense_variant | 0.52 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776005 | p.Ile826Leu | missense_variant | 0.52 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776008 | p.His825Tyr | missense_variant | 0.48 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776009 | c.2472A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776015 | c.2464_2466delATCinsTA | frameshift_variant&synonymous_variant | 0.48 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776018 | c.2463G>C | synonymous_variant | 0.48 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776024 | c.2457G>C | synonymous_variant | 0.48 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776027 | c.2454G>C | synonymous_variant | 0.48 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776030 | c.2451G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776036 | c.2445G>C | synonymous_variant | 0.41 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776053 | c.2428T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776056 | p.Val809Leu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776060 | c.2421C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776072 | c.2409C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776076 | p.Ala802Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777085 | p.Asn466Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777095 | c.1386T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777101 | c.1380C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777110 | c.1371T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777115 | p.Met456Leu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777116 | c.1365C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777133 | p.Val450Ile | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777158 | c.1323C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777164 | c.1317C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777170 | c.1311T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777176 | p.Glu435Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777191 | c.1290C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777194 | c.1287A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777206 | c.1275A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777212 | c.1267_1269delGCCinsAG | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 777215 | c.1266C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777218 | c.1263G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777251 | c.1230C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777254 | c.1227G>C | synonymous_variant | 0.71 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781700 | c.141G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781703 | c.144G>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781772 | c.213C>A | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 0.99 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 0.99 | streptomycin | Uncertain significance |
| rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800627 | c.-182C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.99 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.99 | linezolid | |
| rplC | 800794 | c.-15A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800796 | c.-13A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800817 | c.9A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 0.99 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 0.99 | linezolid | |
| rplC | 800874 | c.66A>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 800875 | c.67_69delGTAinsAT | frameshift_variant&missense_variant | 0.99 | linezolid | |
| rplC | 800880 | c.72A>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 800892 | c.84G>C | synonymous_variant | 0.99 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 0.98 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 0.98 | linezolid | |
| rplC | 800939 | p.Arg44Gln | missense_variant | 0.98 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 800967 | c.159C>G | synonymous_variant | 0.98 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 0.98 | linezolid | Not assoc w R - Interim |
| rplC | 800982 | c.174C>T | synonymous_variant | 0.97 | linezolid | |
| rplC | 800985 | c.177A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 801004 | p.Leu66Val | missense_variant | 1.0 | linezolid | |
| rplC | 801009 | c.201A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801019 | c.211_213delACCinsGG | frameshift_variant&missense_variant | 1.0 | linezolid | |
| rplC | 801027 | c.219C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801039 | c.231A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801114 | c.306C>G | synonymous_variant | 0.88 | linezolid | |
| rplC | 801117 | c.309G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801127 | p.Ala107Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801132 | c.324T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801147 | c.339T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801150 | c.342G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801153 | c.345G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801156 | c.348T>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801168 | c.360C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801171 | c.363A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801174 | c.366T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801180 | c.372C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801195 | c.387G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801201 | c.393C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801207 | c.399C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801246 | c.438C>T | synonymous_variant | 0.99 | linezolid | |
| rplC | 801249 | c.441T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801267 | c.459A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801279 | c.471G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801282 | c.474G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801285 | c.477G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801300 | c.492C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801309 | c.501C>G | synonymous_variant | 0.99 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 0.99 | linezolid | |
| rplC | 801321 | c.513C>T | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801339 | c.531T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 0.99 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801427 | p.Met207Val | missense_variant | 1.0 | linezolid | |
| rplC | 801438 | c.630T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801442 | p.Ile212Val | missense_variant | 1.0 | linezolid | |
| fbiC | 1303431 | c.501T>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303434 | c.504C>T | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303437 | c.507C>G | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303441 | c.511T>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303455 | c.525C>G | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303464 | c.534A>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303476 | c.546G>C | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303480 | p.Gln184Glu | missense_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303489 | c.559C>T | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303497 | c.567G>A | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303501 | c.571C>T | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303521 | c.591C>T | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303530 | c.600G>A | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303539 | c.609G>C | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 0.99 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303614 | c.684C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid |